Ken Mackie

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TOP 3
Diane A Lane; June Chan; Megan L Fitzgerald; Chris S Kearn; Ken Mackie; Virginia M Pickel
Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting.
Pál Pacher; Ken Mackie
Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration.
Alex Straiker; Jim Wager-Miller; Jacqueline Hutchens; Ken Mackie
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.

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All Publications

2012: Diane A Lane; June Chan; Megan L Fitzgerald; Chris S Kearn; Ken Mackie; Virginia M Pickel
Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting.
Psychopharmacology 2012;221(1):101-13.
2012: Pál Pacher; Ken Mackie
Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration.
Journal of molecular medicine (Berlin, Germany) 2012;90(4):347-51.
2012: Alex Straiker; Jim Wager-Miller; Jacqueline Hutchens; Ken Mackie
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.
British journal of pharmacology 2012;165(8):2660-71.
2012: Alex Straiker; Jim Wager-Miller; Ken Mackie
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.
British journal of pharmacology 2012;165(8):2652-9.
2012: Daniel J Morgan; Charles H Muller; Natalia A Murataeva; Brian J Davis; Ken Mackie
Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.
British journal of pharmacology 2012;165(8):2575-83.
2012: Mohanraj Rajesh; Sándor Bátkai; Malek Kechrid; Partha Mukhopadhyay; Wen-Shin Lee; Béla Horváth; Eileen Holovac; Resat Cinar; Lucas Liaudet; Ken Mackie; et al.
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy.
Diabetes 2012;61(3):716-27.
2012: I M Hons; M A Storr; K Mackie; B Lutz; Q J Pittman; G M Mawe; K A Sharkey
Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012;24(3):e113-24.
2012: M Bashashati; M A Storr; S P Nikas; J T Wood; G Godlewski; J Liu; W Ho; C M Keenan; H Zhang; S O Alapafuja; et al.
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.
British journal of pharmacology 2012;165(5):1556-71.
2012: Erik Keimpema; Alex Straiker; Ken Mackie; Tibor Harkany; Jens Hjerling-Leffler
Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells.
The Journal of physiology 2012;590(Pt 4):703-14.
2012: Brady K Atwood; James Wager-Miller; Christopher Haskins; Alex Straiker; Ken Mackie
Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.
Molecular pharmacology 2012;81(2):250-63.
2011: A Straiker; J Wager-Miller; S S Hu; J L Blankman; B F Cravatt; K Mackie
COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation.
British journal of pharmacology 2011;164(6):1672-83.
2011: Erik Keimpema; Ken Mackie; Tibor Harkany
Molecular model of cannabis sensitivity in developing neuronal circuits.
Trends in pharmacological sciences 2011;32(9):551-61.
2011: Matthew N Hill; Ryan J McLaughlin; Bin Pan; Megan L Fitzgerald; Christopher J Roberts; Tiffany T-Y Lee; Ilia N Karatsoreos; Ken Mackie; Victor Viau; Virginia M Pickel; et al.
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(29):10506-15.
2011: Brady K Atwood; Donghoon Lee; Alex Straiker; Theodore S Widlanski; Ken Mackie
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists.
European journal of pharmacology 2011;659(2-3):139-45.
2011: Jan Mulder; Misha Zilberter; Susana J Pasquaré; Alán Alpár; Gunnar Schulte; Samira G Ferreira; Attila Köfalvi; Ana M Martín-Moreno; Erik Keimpema; Heikki Tanila; et al.
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease.
Brain : a journal of neurology 2011;134(Pt 4):1041-60.
2011: Alicia L Richards; Christopher B Lietz; James B Wager-Miller; Ken Mackie; Sarah Trimpin
Imaging mass spectrometry in transmission geometry.
Rapid communications in mass spectrometry : RCM 2011;25(6):815-20.
2011: A Ludányi; S S-J Hu; M Yamazaki; A Tanimura; D Piomelli; M Watanabe; M Kano; K Sakimura; Z Maglóczky; K Mackie; et al.
Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus.
Neuroscience 2011;174():50-63.
2011: Ellen D Inutan; Alicia L Richards; James Wager-Miller; Ken Mackie; Charles N McEwen; Sarah Trimpin
Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation.
Molecular & cellular proteomics : MCP 2011;10(2):M110.000760.
2011: Brady K Atwood; Jacqueline Lopez; James Wager-Miller; Ken Mackie; Alex Straiker
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
BMC genomics 2011;12():14.
2011: Carina Halleskog; Jan Mulder; Jenny Dahlström; Ken Mackie; Tibor Hortobágyi; Heikki Tanila; Lakshman Kumar Puli; Katrin Färber; Tibor Harkany; Gunnar Schulte
WNT signaling in activated microglia is proinflammatory.
Glia 2011;59(1):119-31.
2010: R G Pertwee; A C Howlett; M E Abood; S P H Alexander; V Di Marzo; M R Elphick; P J Greasley; H S Hansen; G Kunos; K Mackie; et al.
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂.
Pharmacological reviews 2010;62(4):588-631.
2010: Sherry Shu-Jung Hu; Andy Arnold; Jacqueline M Hutchens; Josh Radicke; Benjamin F Cravatt; Jim Wager-Miller; Ken Mackie; Alex Straiker
Architecture of cannabinoid signaling in mouse retina.
The Journal of comparative neurology 2010;518(18):3848-66.
2010: Zsófia Maglóczky; Kinga Tóth; Rita Karlócai; Sára Nagy; Loránd Eross; Sándor Czirják; János Vajda; György Rásonyi; Anna Kelemen; Vera Juhos; et al.
Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans.
Epilepsia 2010;51 Suppl 3():115-20.
2010: M A Storr; M Bashashati; C Hirota; V K Vemuri; C M Keenan; M Duncan; B Lutz; K Mackie; A Makriyannis; W K Macnaughton; et al.
Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(7):787-96, e223.
2010: Bani Mukhopadhyay; Jie Liu; Douglas Osei-Hyiaman; Grzegorz Godlewski; Partha Mukhopadhyay; Lei Wang; Won-Il Jeong; Bin Gao; Gregg Duester; Ken Mackie; et al.
Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma.
The Journal of biological chemistry 2010;285(25):19002-11.
2010: Mohanraj Rajesh; Partha Mukhopadhyay; György Haskó; Lucas Liaudet; Ken Mackie; Pál Pacher
Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.
British journal of pharmacology 2010;160(3):688-700.
2010: Partha Mukhopadhyay; Hao Pan; Mohanraj Rajesh; Sándor Bátkai; Vivek Patel; Judith Harvey-White; Bani Mukhopadhyay; György Haskó; Bin Gao; Ken Mackie; et al.
CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model.
British journal of pharmacology 2010;160(3):657-68.
2010: Brady K Atwood; Ken Mackie
CB2: a cannabinoid receptor with an identity crisis.
British journal of pharmacology 2010;160(3):467-79.
2010: Brady K Atwood; John Huffman; Alex Straiker; Ken Mackie
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist.
British journal of pharmacology 2010;160(3):585-93.
2010: Federico Massa; Giacomo Mancini; Helmut Schmidt; Frauke Steindel; Ken Mackie; Carlo Angioni; Stéphane H R Oliet; Gerd Geisslinger; Beat Lutz
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(18):6273-81.
2010: Partha Mukhopadhyay; Mohanraj Rajesh; Sándor Bátkai; Vivek Patel; Yoshihiro Kashiwaya; Lucas Liaudet; Oleg V Evgenov; Ken Mackie; György Haskó; Pál Pacher
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Cardiovascular research 2010;85(4):773-84.
2010: Jillian L Scavone; Ken Mackie; Elisabeth J Van Bockstaele
Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors.
Brain research 2010;1312():18-31.
2010: Sarah Trimpin; Thushani N Herath; Ellen D Inutan; Jim Wager-Miller; Paul Kowalski; Emmanuelle Claude; J Michael Walker; Ken Mackie
Automated solvent-free matrix deposition for tissue imaging by mass spectrometry.
Analytical chemistry 2010;82(1):359-67.
2009: Alex Straiker; Sherry Shu-Jung Hu; Jonathan Z Long; Andy Arnold; Jim Wager-Miller; Benjamin F Cravatt; Ken Mackie
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
Molecular pharmacology 2009;76(6):1220-7.
2009: A Straiker; K Mackie
Cannabinoid signaling in inhibitory autaptic hippocampal neurons.
Neuroscience 2009;163(1):190-201.
2009: Lauren S Whyte; Erik Ryberg; Natalie A Sims; Susan A Ridge; Ken Mackie; Peter J Greasley; Ruth A Ross; Michael J Rogers
The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16511-6.
2009: Ken Mackie; István Katona
Get stoned in GABAergic synapses.
Nature neuroscience 2009;12(9):1081-3.
2009: Sarah Trimpin; Thushani N Herath; Ellen D Inutan; S Alexandru Cernat; James B Miller; Ken Mackie; J Michael Walker
Field-free transmission geometry atmospheric pressure matrix-assisted laser desorption/ionization for rapid analysis of unadulterated tissue samples.
Rapid communications in mass spectrometry : RCM 2009;23(18):3023-7.
2009: Ryan Kellogg; Ken Mackie; Alex Straiker
Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons.
Journal of neurophysiology 2009;102(2):1160-71.
2009: E Trabucco; G Acone; A Marenna; R Pierantoni; G Cacciola; T Chioccarelli; K Mackie; S Fasano; N Colacurci; R Meccariello; et al.
Endocannabinoid system in first trimester placenta: low FAAH and high CB1 expression characterize spontaneous miscarriage.
Placenta 2009;30(6):516-22.
2009: Rita Nyilas; Laura C Gregg; Ken Mackie; Masahiko Watanabe; Andreas Zimmer; Andrea G Hohmann; István Katona
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia.
The European journal of neuroscience 2009;29(10):1964-78.
2009: Erika Cottone; Alda Guastalla; Valentina Pomatto; Ezio Campantico; Francesco Palermo; Alberta Maria Polzonetti Magni; Ken Mackie; Maria Fosca Franzoni
Interplay of the endocannabinoid system with neuropeptide Y and corticotropin-releasing factor in the goldfish forebrain.
Annals of the New York Academy of Sciences 2009;1163():372-5.
2009: Sergi Ferré; Ruben Baler; Michel Bouvier; Marc G Caron; Lakshmi A Devi; Thierry Durroux; Kjell Fuxe; Susan R George; Jonathan A Javitch; Martin J Lohse; et al.
Building a new conceptual framework for receptor heteromers.
Nature chemical biology 2009;5(3):131-4.
2009: G Acone; E Trabucco; N Colacurci; L Cobellis; K Mackie; R Meccariello; G Cacciola; T Chioccarelli; S Fasano; R Pierantoni; et al.
Low type I cannabinoid receptor levels characterize placental villous in labouring delivery.
Placenta 2009;30(2):203-5.
2009: Xiaofei Sun; Haibin Wang; Masaru Okabe; Kenneth Mackie; Philip J Kingsley; Lawrence J Marnett; Benjamin F Cravatt; Sudhansu K Dey
Genetic loss of Faah compromises male fertility in mice.
Biology of reproduction 2009;80(2):235-42.
2008: Giovanna Cacciola; Teresa Chioccarelli; Ken Mackie; Rosaria Meccariello; Catherine Ledent; Silvia Fasano; Riccardo Pierantoni; Gilda Cobellis
Expression of type-1 cannabinoid receptor during rat postnatal testicular development: possible involvement in adult leydig cell differentiation.
Biology of reproduction 2008;79(4):758-65.
2008: Juan Suárez; Francisco Javier Bermúdez-Silva; Ken Mackie; Catherine Ledent; Andreas Zimmer; Benjamin F Cravatt; Fernando Rodríguez de Fonseca
Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei.
The Journal of comparative neurology 2008;509(4):400-21.
2008: Arieh Moussaieff; Neta Rimmerman; Tatiana Bregman; Alex Straiker; Christian C Felder; Shai Shoham; Yoel Kashman; Susan M Huang; Hyosang Lee; Esther Shohami; et al.
Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):3024-34.
2008: Marnie Duncan; Abdeslam Mouihate; Ken Mackie; Catherine M Keenan; Nancy E Buckley; Joseph S Davison; Kamala D Patel; Quentin J Pittman; Keith A Sharkey
Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(1):G78-G87.
2008: Tanya L Daigle; Mary Lee Kwok; Ken Mackie
Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism.
Journal of neurochemistry 2008;106(1):70-82.
2008: Jan Mulder; Tania Aguado; Erik Keimpema; Klaudia Barabás; Carlos J Ballester Rosado; Laurent Nguyen; Krisztina Monory; Giovanni Marsicano; Vincenzo Di Marzo; Yasmin L Hurd; et al.
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8760-5.
2008: Tibor Harkany; Ken Mackie; Patrick Doherty
Wiring and firing neuronal networks: endocannabinoids take center stage.
Current opinion in neurobiology 2008;18(3):338-45.
2008: Resat Cinar; Tamas F Freund; Istvan Katona; Ken Mackie; Maria Szucs
Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes.
Neurochemistry international 2008;52(8):1402-9.
2008: K Mackie
Cannabinoid receptors: where they are and what they do.
Journal of neuroendocrinology 2008;20 Suppl 1():10-4.
2008: E Cottone; A Guastalla; K Mackie; M F Franzoni
Endocannabinoids affect the reproductive functions in teleosts and amphibians.
Molecular and cellular endocrinology 2008;286(1-2 Suppl 1):S41-5.
2008: Ken Mackie
Signaling via CNS cannabinoid receptors.
Molecular and cellular endocrinology 2008;286(1-2 Suppl 1):S60-5.
2008: D T Malone; C S Kearn; L Chongue; K Mackie; D A Taylor
Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats.
Neuroscience 2008;152(1):265-72.
2008: Jane E Lauckner; Jill B Jensen; Huei-Ying Chen; Hui-Chen Lu; Bertil Hille; Ken Mackie
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2699-704.
2008: Rita Nyilas; Barna Dudok; Gabriella M Urbán; Ken Mackie; Masahiko Watanabe; Benjamin F Cravatt; Tamás F Freund; István Katona
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(5):1058-63.
2008: M Rajesh; P Mukhopadhyay; G Haskó; J W Huffman; K Mackie; P Pacher
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration.
British journal of pharmacology 2008;153(2):347-57.
2008: N Rimmerman; H V Hughes; H B Bradshaw; M X Pazos; K Mackie; A L Prieto; J M Walker
Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line.
British journal of pharmacology 2008;153(2):380-9.
2008: Tanya L Daigle; Christopher S Kearn; Ken Mackie
Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling.
Neuropharmacology 2008;54(1):36-44.
2008: Ferenc Mátyás; Gabriella M Urbán; Masahiko Watanabe; Ken Mackie; Andreas Zimmer; Tamás F Freund; István Katona
Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area.
Neuropharmacology 2008;54(1):95-107.
2007: Roger Cachope; Ken Mackie; Antoine Triller; John O'Brien; Alberto E Pereda
Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids.
Neuron 2007;56(6):1034-47.
2007: Ken Mackie
Understanding cannabinoid psychoactivity with mouse genetic models.
PLoS biology 2007;5(10):e280.
2007: Mohanraj Rajesh; Partha Mukhopadhyay; Sándor Bátkai; György Haskó; Lucas Liaudet; John W Huffman; Anna Csiszar; Zoltan Ungvari; Ken Mackie; Subroto Chatterjee; et al.
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2210-8.
2007: Kwang-Mook Jung; Giuseppe Astarita; Chenggang Zhu; Matthew Wallace; Ken Mackie; Daniele Piomelli
A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.
Molecular pharmacology 2007;72(3):612-21.
2007: Ken Mackie
From active ingredients to the discovery of the targets: the cannabinoid receptors.
Chemistry & biodiversity 2007;4(8):1693-706.
2007: Nitin Agarwal; Pal Pacher; Irmgard Tegeder; Fumimasa Amaya; Cristina E Constantin; Gary J Brenner; Tiziana Rubino; Christoph W Michalski; Giovanni Marsicano; Krisztina Monory; et al.
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Nature neuroscience 2007;10(7):870-9.
2007: M P Castelli; A P Piras; T Melis; S Succu; F Sanna; M R Melis; S Collu; M Grazia Ennas; G Diaz; K Mackie; et al.
Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies.
Neuroscience 2007;147(1):197-206.
2007: Paul Berghuis; Ann M Rajnicek; Yury M Morozov; Ruth A Ross; Jan Mulder; Gabriella M Urbán; Krisztina Monory; Giovanni Marsicano; Michela Matteoli; Alison Canty; et al.
Hardwiring the brain: endocannabinoids shape neuronal connectivity.
Science (New York, N.Y.) 2007;316(5828):1212-6.
2007: Somsak Mitrirattanakul; Héctor E López-Valdés; Jing Liang; Yoshizo Matsuka; Ken Mackie; Kym F Faull; Igor Spigelman
Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence.
Alcoholism, clinical and experimental research 2007;31(5):855-67.
2007: Anke Tappe-Theodor; Nitin Agarwal; István Katona; Tiziana Rubino; Lene Martini; Jakub Swiercz; Ken Mackie; Hannah Monyer; Daniela Parolaro; Jennifer Whistler; et al.
A molecular basis of analgesic tolerance to cannabinoids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(15):4165-77.
2007: Ferenc Mátyás; Masahiko Watanabe; Ken Mackie; István Katona; Tamás F Freund
Molecular architecture of the cannabinoid signaling system in the core of the nucleus accumbens.
Ideggyógyászati szemle 2007;60(3-4):187-91.
2007: S Deshmukh; K Onozuka; K J Bender; V A Bender; B Lutz; K Mackie; D E Feldman
Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex.
Neuroscience 2007;145(1):279-87.
2007: João M N Duarte; Célia Nogueira; Ken Mackie; Catarina R Oliveira; Rodrigo A Cunha; Attila Köfalvi
Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats.
Experimental neurology 2007;204(1):479-84.
2007: Tibor Harkany; Manuel Guzmán; Ismael Galve-Roperh; Paul Berghuis; Lakshmi A Devi; Ken Mackie
The emerging functions of endocannabinoid signaling during CNS development.
Trends in pharmacological sciences 2007;28(2):83-92.
2007: Alex Straiker; Ken Mackie
Metabotropic suppression of excitation in murine autaptic hippocampal neurons.
The Journal of physiology 2007;578(Pt 3):773-85.
2007: Jin Fu; Giuseppe Astarita; Silvana Gaetani; Janet Kim; Benjamin F Cravatt; Ken Mackie; Daniele Piomelli
Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine.
The Journal of biological chemistry 2007;282(2):1518-28.
2007: Veronica C Oropeza; Kenneth Mackie; Elisabeth J Van Bockstaele
Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex.
Brain research 2007;1127(1):36-44.
2007: Kang Chen; Axel Neu; Allyson L Howard; Csaba Földy; Julio Echegoyen; Lutz Hilgenberg; Martin Smith; Ken Mackie; Ivan Soltesz
Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(1):46-58.
2006: Somsak Mitrirattanakul; Navapoln Ramakul; Andre V Guerrero; Yoshizo Matsuka; Takeshi Ono; Hirotate Iwase; Ken Mackie; Kym F Faull; Igor Spigelman
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain.
Pain 2006;126(1-3):102-14.
2006: Gabriele Cenni; Patrizio Blandina; Ken Mackie; Daniele Nosi; Lucia Formigli; Patrizia Giannoni; Chiara Ballini; Laura Della Corte; Pier Francesco Mannaioni; M Beatrice Passani
Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain.
The European journal of neuroscience 2006;24(6):1633-44.
2006: Joseph Tam; Orr Ofek; Ester Fride; Catherine Ledent; Yankel Gabet; Ralph Müller; Andreas Zimmer; Ken Mackie; Raphael Mechoulam; Esther Shohami; et al.
Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling.
Molecular pharmacology 2006;70(3):786-92.
2006: Krisztina Monory; Federico Massa; Michaela Egertová; Matthias Eder; Heike Blaudzun; Ruth Westenbroek; Wolfgang Kelsch; Wolfgang Jacob; Rudolf Marsch; Marc Ekker; et al.
The endocannabinoid system controls key epileptogenic circuits in the hippocampus.
Neuron 2006;51(4):455-66.
2006: Sebastian Schuchmann; Dietmar Schmitz; Claudio Rivera; Sampsa Vanhatalo; Benedikt Salmen; Ken Mackie; Sampsa T Sipilä; Juha Voipio; Kai Kaila
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.
Nature medicine 2006;12(7):817-23.
2006: Gilda Cobellis; Giovanna Cacciola; Donatella Scarpa; Rosaria Meccariello; Rosanna Chianese; Maria Fosca Franzoni; Ken Mackie; Riccardo Pierantoni; Silvia Fasano
Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells.
Biology of reproduction 2006;75(1):82-9.
2006: István Katona; Gabriella M Urbán; Matthew Wallace; Catherine Ledent; Kwang-Mook Jung; Daniele Piomelli; Ken Mackie; Tamás F Freund
Molecular composition of the endocannabinoid system at glutamatergic synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(21):5628-37.
2006: K Mackie
Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength.
International journal of obesity (2005) 2006;30 Suppl 1():S19-23.
2006: Virgina M Pickel; Jane Chan; Christopher S Kearn; Kenneth Mackie
Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens.
The Journal of comparative neurology 2006;495(3):299-313.
2006: Ken Mackie; Nephi Stella
Cannabinoid receptors and endocannabinoids: evidence for new players.
The AAPS journal 2006;8(2):E298-306.
2006: Alex Straiker; Ken Mackie
Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years.
The AAPS journal 2006;8(2):E272-6.
2006: Ken Mackie
Cannabinoid receptors as therapeutic targets.
Annual review of pharmacology and toxicology 2006;46():101-22.
2006: F Mátyás; Y Yanovsky; K Mackie; W Kelsch; U Misgeld; T F Freund
Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia.
Neuroscience 2006;137(1):337-61.
2005: Jane E Lauckner; Bertil Hille; Ken Mackie
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):19144-9.
2005: Paul Berghuis; Marton B Dobszay; Xinyu Wang; Sabrina Spano; Fernanda Ledda; Kyle M Sousa; Gunnar Schulte; Patrik Ernfors; Ken Mackie; Gustavo Paratcha; et al.
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):19115-20.
2005: Alex Straiker; Ken Mackie
Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones.
The Journal of physiology 2005;569(Pt 2):501-17.
2005: Kwang-Mook Jung; Regina Mangieri; Christopher Stapleton; Janet Kim; Darren Fegley; Matthew Wallace; Ken Mackie; Daniele Piomelli
Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors.
Molecular pharmacology 2005;68(5):1196-202.
2005: Marja D Van Sickle; Marnie Duncan; Philip J Kingsley; Abdeslam Mouihate; Paolo Urbani; Ken Mackie; Nephi Stella; Alexandros Makriyannis; Daniele Piomelli; Joseph S Davison; et al.
Identification and functional characterization of brainstem cannabinoid CB2 receptors.
Science (New York, N.Y.) 2005;310(5746):329-32.
2005: Lisa F Horowitz; Wiebke Hirdes; Byung-Chang Suh; Donald W Hilgemann; Ken Mackie; Bertil Hille
Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.
The Journal of general physiology 2005;126(3):243-62.
2005: Ken Mackie
Cannabinoid receptor homo- and heterodimerization.
Life sciences 2005;77(14):1667-73.
2005: Agnes L Bodor; István Katona; Gábor Nyíri; Ken Mackie; Catherine Ledent; Norbert Hájos; Tamás F Freund
Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(29):6845-56.
2005: Gábor Nyíri; Eszter Szabadits; Csaba Cserép; Ken Mackie; Ryuichi Shigemoto; Tamás F Freund
GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons.
The European journal of neuroscience 2005;21(11):3034-42.
2005: Erika Cottone; Sarah Forno; Ezio Campantico; Alda Guastalla; Laura Viltono; Ken Mackie; Maria Fosca Franzoni
Expression and distribution of CB1 cannabinoid receptors in the central nervous system of the African cichlid fish Pelvicachromis pulcher.
The Journal of comparative neurology 2005;485(4):293-303.
2005: Douglas Osei-Hyiaman; Michael DePetrillo; Pál Pacher; Jie Liu; Svetlana Radaeva; Sándor Bátkai; Judith Harvey-White; Ken Mackie; László Offertáler; Lei Wang; et al.
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity.
The Journal of clinical investigation 2005;115(5):1298-305.
2005: Christopher S Kearn; Katherine Blake-Palmer; Emma Daniel; Ken Mackie; Michelle Glass
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?
Molecular pharmacology 2005;67(5):1697-704.
2005: Attila Köfalvi; Ricardo J Rodrigues; Catherine Ledent; Ken Mackie; E Sylvester Vizi; Rodrigo A Cunha; Beáta Sperlágh
Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(11):2874-84.
2005: Cristina Benito; Woong-Ki Kim; Wong-Ki Kim; Iván Chavarría; Ceceila J Hillard; Ken Mackie; Rosa M Tolón; Kenneth Williams; Ken Williams; Julián Romero
A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2530-6.
2005: K Mackie
Distribution of cannabinoid receptors in the central and peripheral nervous system.
Handbook of experimental pharmacology 2005;(168):299-325.
2005: G Nyíri; C Cserép; E Szabadits; K Mackie; T F Freund
CB1 cannabinoid receptors are enriched in the perisynaptic annulus and on preterminal segments of hippocampal GABAergic axons.
Neuroscience 2005;136(3):811-22.
2005: Douglas Osei-Hyiaman; Michael Depetrillo; Judith Harvey-White; Anthony W Bannon; Benjamin F Cravatt; Michael J Kuhar; Ken Mackie; Miklós Palkovits; George Kunos
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
Neuroendocrinology 2005;81(4):273-82.
2005: T Harkany; M B Dobszay; F Cayetanot; W Härtig; T Siegemund; F Aujard; K Mackie
Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat.
Neuroscience 2005;135(2):595-609.
2004: Sándor Bátkai; Pál Pacher; Douglas Osei-Hyiaman; Svetlana Radaeva; Jie Liu; Judith Harvey-White; László Offertáler; Ken Mackie; M Audrey Rudd; Richard D Bukoski; et al.
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Circulation 2004;110(14):1996-2002.
2004: Michiru Hirasawa; Yannick Schwab; Sirajedin Natah; Cecilia J Hillard; Ken Mackie; Keith A Sharkey; Quentin J Pittman
Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain.
The Journal of physiology 2004;559(Pt 2):611-24.
2004: Byung-Chang Suh; Lisa F Horowitz; Wiebke Hirdes; Ken Mackie; Bertil Hille
Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.
The Journal of general physiology 2004;123(6):663-83.
2004: Terry Luk; Wenzhen Jin; Alexander Zvonok; Dai Lu; Xin-Zhong Lin; Charles Chavkin; Alexandros Makriyannis; Ken Mackie
Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist.
British journal of pharmacology 2004;142(3):495-500.
2004: Tibor Harkany; Carl Holmgren; Wolfgang Härtig; Tayyaba Qureshi; Farrukh A Chaudhry; Jon Storm-Mathisen; Marton B Dobszay; Paul Berghuis; Gunnar Schulte; Kyle M Sousa; et al.
Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(21):4978-88.
2004: Wallace K MacNaughton; Marja D Van Sickle; Catherine M Keenan; Kelly Cushing; Ken Mackie; Keith A Sharkey
Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(5):G863-71.
2004: V M Pickel; J Chan; T L Kash; J J Rodríguez; K MacKie
Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens.
Neuroscience 2004;127(1):101-12.
2003: Tibor Harkany; Wolfgang Härtig; Paul Berghuis; Marton B Dobszay; Yuri Zilberter; Robert H Edwards; Ken Mackie; Patrik Ernfors
Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons.
The European journal of neuroscience 2003;18(7):1979-92.
2003: Jay P McLaughlin; Mei Xu; Ken Mackie; Charles Chavkin
Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization.
The Journal of biological chemistry 2003;278(36):34631-40.
2003: Marja D Van Sickle; Lorraine D Oland; Ken Mackie; Joseph S Davison; Keith A Sharkey
Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(3):G566-76.
2003: Kang Chen; Anna Ratzliff; Lutz Hilgenberg; Attila Gulyás; Tamás F Freund; Martin Smith; Thien P Dinh; Daniele Piomelli; Ken Mackie; Ivan Soltesz
Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures.
Neuron 2003;39(4):599-611.
2003: Lisa Walter; Allyn Franklin; Anke Witting; Christian Wade; Yiheng Xie; George Kunos; Ken Mackie; Nephi Stella
Nonpsychotropic cannabinoid receptors regulate microglial cell migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(4):1398-405.
2002: James Wager-Miller; Ruth Westenbroek; Ken Mackie
Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example.
Chemistry and physics of lipids 2002;121(1-2):83-9.
2002: John P Roche; Ruth Westenbroek; Abraham J Sorom; Bertil Hille; Ken Mackie; Mark S Shapiro
Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels.
British journal of pharmacology 2002;137(8):1173-86.
2002: Sean M Brown; James Wager-Miller; Ken Mackie
Cloning and molecular characterization of the rat CB2 cannabinoid receptor.
Biochimica et biophysica acta 2002;1576(3):255-64.
2002: Angela A Coutts; Andrew J Irving; Ken Mackie; Roger G Pertwee; Sharon Anavi-Goffer
Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus.
The Journal of comparative neurology 2002;448(4):410-22.
2002: A C Howlett; F Barth; T I Bonner; G Cabral; P Casellas; W A Devane; C C Felder; M Herkenham; K Mackie; B R Martin; et al.
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors.
Pharmacological reviews 2002;54(2):161-202.
2002: R Cesa; A Guastalla; E Cottone; K Mackie; M Beltramo; M F Franzoni
Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study.
General and comparative endocrinology 2002;125(1):17-24.
2002: Marco A Diana; Carole Levenes; Ken Mackie; Alain Marty
Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(1):200-8.
2001: C Salio; J Fischer; M F Franzoni; K Mackie; T Kaneko; M Conrath
CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn.
Neuroreport 2001;12(17):3689-92.
2001: R Cesa; K Mackie; M Beltramo; M F Franzoni
Cannabinoid receptor CB1-like and glutamic acid decarboxylase-like immunoreactivities in the brain of Xenopus laevis.
Cell and tissue research 2001;306(3):391-8.
2001: I Katona; E A Rancz; L Acsady; C Ledent; K Mackie; N Hajos; T F Freund
Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(23):9506-18.
2001: M D Van Sickle; L D Oland; W Ho; C J Hillard; K Mackie; J S Davison; K A Sharkey
Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret.
Gastroenterology 2001;121(4):767-74.
2001: A A Coutts; S Anavi-Goffer; R A Ross; D J MacEwan; K Mackie; R G Pertwee; A J Irving
Agonist-induced internalization and trafficking of cannabinoid CB1 receptors in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(7):2425-33.
2001: J J Rodriguez; K Mackie; V M Pickel
Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(3):823-33.
2000: A Calignano; I Kátona; F Désarnaud; A Giuffrida; G La Rana; K Mackie; T F Freund; D Piomelli
Bidirectional control of airway responsiveness by endogenous cannabinoids.
Nature 2000;408(6808):96-101.
2000: N Hájos; I Katona; S S Naiem; K MacKie; C Ledent; I Mody; T F Freund
Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations.
The European journal of neuroscience 2000;12(9):3239-49.
2000: M S Shapiro; J P Roche; E J Kaftan; H Cruzblanca; K Mackie; B Hille
Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(5):1710-21.
2000: M Hernández; F Berrendero; I Suárez; L García-Gil; M Cebeira; K Mackie; J A Ramos; J Fernández-Ruiz
Cannabinoid CB(1) receptors colocalize with tyrosine hydroxylase in cultured fetal mesencephalic neurons and their activation increases the levels of this enzyme.
Brain research 2000;857(1-2):56-65.
2000: M C Sañudo-Peña; K Tsou; J Romero; K Mackie; J M Walker
Role of the superior colliculus in the motor effects of cannabinoids and dopamine.
Brain research 2000;853(2):207-14.
2000: I Katona; B Sperlágh; Z Maglóczky; E Sántha; A Köfalvi; S Czirják; K Mackie; E S Vizi; T F Freund
GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus.
Neuroscience 2000;100(4):797-804.
2000: A J Irving; A A Coutts; J Harvey; M G Rae; K Mackie; G S Bewick; R G Pertwee
Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons.
Neuroscience 2000;98(2):253-62.
1999: A Straiker; N Stella; D Piomelli; K Mackie; H J Karten; G Maguire
Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14565-70.
1999: M C Sañudo-Peña; N M Strangman; K Mackie; J M Walker; K Tsou
CB1 receptor localization in rat spinal cord and roots, dorsal root ganglion, and peripheral nerve.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1999;20(12):1115-20.
1999: X R Lu; W Y Ong; K Mackie
A light and electron microscopic study of the CB1 cannabinoid receptor in monkey basal forebrain.
Journal of neurocytology 1999;28(12):1045-51.
1999: A J Straiker; G Maguire; K Mackie; J Lindsey
Localization of cannabinoid CB1 receptors in the human anterior eye and retina.
Investigative ophthalmology & visual science 1999;40(10):2442-8.
1999: J P Roche; S Bounds; S Brown; K Mackie
A mutation in the second transmembrane region of the CB1 receptor selectively disrupts G protein signaling and prevents receptor internalization.
Molecular pharmacology 1999;56(3):611-8.
1999: C Hsieh; S Brown; C Derleth; K Mackie
Internalization and recycling of the CB1 cannabinoid receptor.
Journal of neurochemistry 1999;73(2):493-501.
1999: I Katona; B Sperlágh; A Sík; A Käfalvi; E S Vizi; K Mackie; T F Freund
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4544-58.
1999: W Jin; S Brown; J P Roche; C Hsieh; J P Celver; A Kovoor; C Chavkin; K Mackie
Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(10):3773-80.
1999: W Y Ong; K Mackie
A light and electron microscopic study of the CB1 cannabinoid receptor in the primate spinal cord.
Journal of neurocytology 1999;28(1):39-45.
1999: K Tsou; K Mackie; M C Sañudo-Peña; J M Walker
Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation.
Neuroscience 1999;93(3):969-75.
1999: W Y Ong; K Mackie
A light and electron microscopic study of the CB1 cannabinoid receptor in primate brain.
Neuroscience 1999;92(4):1177-91.
1998: D E García; B Li; R E García-Ferreiro; E O Hernández-Ochoa; K Yan; N Gautam; W A Catterall; K Mackie; B Hille
G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9163-70.
1998: D E Garcia; S Brown; B Hille; K Mackie
Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(8):2834-41.
1998: K Tsou; S Brown; M C Sañudo-Peña; K Mackie; J M Walker
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system.
Neuroscience 1998;83(2):393-411.
1998: C C Felder; K E Joyce; E M Briley; M Glass; K P Mackie; K J Fahey; G J Cullinan; D C Hunden; D W Johnson; M O Chaney; et al.
LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation.
The Journal of pharmacology and experimental therapeutics 1998;284(1):291-7.
1997: W Twitchell; S Brown; K Mackie
Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons.
Journal of neurophysiology 1997;78(1):43-50.
1997: W A Baguley; W T Hay; K P Mackie; F W Cheney; B F Cullen
Cardiac dysrhythmias associated with the intravenous administration of ondansetron and metoclopramide.
Anesthesia and analgesia 1997;84(6):1380-1.
1996: S Herlitze; D E Garcia; K Mackie; B Hille; T Scheuer; W A Catterall
Modulation of Ca2+ channels by G-protein beta gamma subunits.
Nature 1996;380(6571):258-62.
1995: K Mackie; Y Lai; R Westenbroek; R Mitchell
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(10):6552-61.
1995: C C Felder; K E Joyce; E M Briley; J Mansouri; K Mackie; O Blond; Y Lai; A L Ma; R L Mitchell
Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.
Molecular pharmacology 1995;48(3):443-50.
1995: J Priller; E M Briley; J Mansouri; W A Devane; K Mackie; C C Felder
Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors.
Molecular pharmacology 1995;48(2):288-92.
1993: K Mackie; W A Devane; B Hille
Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells.
Molecular pharmacology 1993;44(3):498-503.
1993: C C Felder; E M Briley; J Axelrod; J T Simpson; K Mackie; W A Devane
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7656-60.
1992: K Mackie; B Hille
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):3825-9.
1991: K Mackie; A Lam
Epinephrine-containing test dose during beta-blockade.
Journal of clinical monitoring 1991;7(3):213-6.
1990: K Mackie; E G Pavlin
Recurrent paralysis following piperacillin administration.
Anesthesiology 1990;72(3):561-3.
1989: K Mackie; B C Sorkin; A C Nairn; P Greengard; G M Edelman; B A Cunningham
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):1883-96.
1989: K P Mackie; A C Nairn; G Hampel; G Lam; E A Jaffe
Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells.
The Journal of biological chemistry 1989;264(3):1748-53.
1986: K Mackie; M DePasquale; H F Cserr
Increased permeability of a glial blood-brain barrier during acute hyperosmotic stress.
The American journal of physiology 1986;251(6 Pt 2):R1186-92.
1986: K Mackie; Y Lai; A C Nairn; P Greengard; B R Pitt; J S Lazo
Protein phosphorylation in cultured endothelial cells.
Journal of cellular physiology 1986;128(3):367-74.