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Genevieve Sparagna

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Janice V Huang; Li Lu; Jane E B Reusch; Mohammad Sarraf; Bryan C Bergman; Clifford Greyson; Genevieve C Sparagna; Shuyu Ye; Gregory G Schwartz
Impaired contractile recovery after low-flow myocardial ischemia in a porcine model of metabolic syndrome.
Soledad Bazán; Philip Heacock; Venkata K P S Mallampalli; Eugenia Mileykovskaya; Genevieve C Sparagna; William Dowhan
Cardiolipin-dependent reconstitution of respiratory supercomplexes from purified Saccharomyces cerevisiae complexes III and IV.
Eugenia Mileykovskaya; Pawel A Penczek; Genevieve C Sparagna; Jia Fang; Venkata K P S Mallampalli; William Dowhan
Arrangement of the respiratory chain complexes in Saccharomyces cerevisiae supercomplex III2IV2 revealed by single particle cryo-electron microscopy.

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All Publications

2013: Janice V Huang; Li Lu; Jane E B Reusch; Mohammad Sarraf; Bryan C Bergman; Clifford Greyson; Genevieve C Sparagna; Shuyu Ye; Gregory G Schwartz
Impaired contractile recovery after low-flow myocardial ischemia in a porcine model of metabolic syndrome.
American journal of physiology. Heart and circulatory physiology 2013;304(6):H861-73.
2013: Soledad Bazán; Philip Heacock; Venkata K P S Mallampalli; Eugenia Mileykovskaya; Genevieve C Sparagna; William Dowhan
Cardiolipin-dependent reconstitution of respiratory supercomplexes from purified Saccharomyces cerevisiae complexes III and IV.
The Journal of biological chemistry 2013;288(1):401-11.
2012: Eugenia Mileykovskaya; Pawel A Penczek; Genevieve C Sparagna; Jia Fang; Venkata K P S Mallampalli; William Dowhan
Arrangement of the respiratory chain complexes in Saccharomyces cerevisiae supercomplex III2IV2 revealed by single particle cryo-electron microscopy.
The Journal of biological chemistry 2012;287(27):23095-103.
2012: Christopher M Mulligan; Robert C Murphy; Melissa A Routh; Genevieve C Sparagna; Fred Y Xu; Simona Zarini; Anthony B De Mooy; Grant M Hatch; Diane L Hickson-Bick; Michael G Holmes; Catherine H Le; Sylvia A McCune; Russell L Moore; Adam J Chicco
Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart.
Cardiovascular research 2012;94(3):460-8.
2012: William A Taylor; Patrick C Choy; Edgard M Mejia; Ryan W Mitchell; Genevieve C Sparagna; Grant M Hatch
Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation.
PloS one 2012;7(11):e48628.
2011: Harjot K Saini-Chohan; Garry X Shen; Genevieve C Sparagna; William A Taylor; Shyamala Dakshinamurti; Robert Murphy; Grant M Hatch
Persistent pulmonary hypertension results in reduced tetralinoleoyl-cardiolipin and mitochondrial complex II + III during the development of right ventricular hypertrophy in the neonatal pig heart.
American journal of physiology. Heart and circulatory physiology 2011;301(4):H1415-24.
2010: Ramzi J Khairallah; Genevieve C Sparagna; Nishanth Khanna; Karen M O'Shea; Peter A Hecker; Tibor Kristian; Gary Fiskum; Christine Des Rosiers; Brian M Polster; William C Stanley
Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.
Biochimica et biophysica acta 2010;1797(8):1555-62.
2010: Derek K Zachman; Adam J Chicco; Sylvia A McCune; Robert C Murphy; Russell L Moore; Genevieve C Sparagna
The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart.
Journal of lipid research 2010;51(3):525-34.
2009: Karen M O'Shea; Ramzi J Khairallah; Genevieve C Sparagna; Wenhong Xu; Peter A Hecker; Isabelle Robillard-Frayne; Christine Des Rosiers; Tibor Kristian; Robert C Murphy; Gary Fiskum; William C Stanley
Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.
Journal of molecular and cellular cardiology 2009;47(6):819-27.
2009: Keyur B Shah; Monika K Duda; Karen M O'Shea; Genevieve C Sparagna; David J Chess; Ramzi J Khairallah; Isabelle Robillard-Frayne; Wenhong Xu; Robert C Murphy; Christine Des Rosiers; William C Stanley
The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling.
Hypertension 2009;54(3):605-11.
2009: Harjot K Saini-Chohan; Michael G Holmes; Adam J Chicco; William A Taylor; Russell L Moore; Sylvia A McCune; Diane L Hickson-Bick; Grant M Hatch; Genevieve C Sparagna
Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure.
Journal of lipid research 2009;50(8):1600-8.
2009: Genevieve C Sparagna; Edward J Lesnefsky
Cardiolipin remodeling in the heart.
Journal of cardiovascular pharmacology 2009;53(4):290-301.
2008: Eric Gumpricht; Michael W Devereaux; Rolf Dahl; Jason S Soden; Genevieve C Sparagna; Scott W Leonard; Maret G Traber; Ronald Sokol
Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol.
Pediatric research 2008;64(5):498-504.
2008: Adam J Chicco; Genevieve C Sparagna; Sylvia A McCune; Christopher A Johnson; Robert C Murphy; David A Bolden; Meredith L Rees; Ryan T Gardner; Russell L Moore
Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets.
Hypertension 2008;52(3):549-55.
2008: Adam J Chicco; Sylvia A McCune; Craig A Emter; Genevieve C Sparagna; Meredith L Rees; David A Bolden; Kurt D Marshall; Robert C Murphy; Russell L Moore
Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats.
Hypertension 2008;51(4):1096-102.
2007: Genevieve C Sparagna; Adam J Chicco; Robert C Murphy; Michael R Bristow; Christopher A Johnson; Meredith L Rees; Melissa L Maxey; Sylvia A McCune; Russell L Moore
Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure.
Journal of lipid research 2007;48(7):1559-70.
2007: Peter A Watson; Jane E B Reusch; Sylvia A McCune; Leslie A Leinwand; Stephen W Luckey; John P Konhilas; David A Brown; Adam J Chicco; Genevieve C Sparagna; Carlin S Long; Russell L Moore
Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H246-59.
2007: Adam J Chicco; Genevieve C Sparagna
Role of cardiolipin alterations in mitochondrial dysfunction and disease.
American journal of physiology. Cell physiology 2007;292(1):C33-44.
2005: Craig A Emter; Sylvia A McCune; Genevieve C Sparagna; M Judith Radin; Russell L Moore
Low-intensity exercise training delays onset of decompensated heart failure in spontaneously hypertensive heart failure rats.
American journal of physiology. Heart and circulatory physiology 2005;289(5):H2030-8.
2005: Genevieve C Sparagna; Chris A Johnson; Sylvia A McCune; Russell L Moore; Robert C Murphy
Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry.
Journal of lipid research 2005;46(6):1196-204.
2004: Genevieve C Sparagna; Chad E Jones; Diane L M Hickson-Bick
Attenuation of fatty acid-induced apoptosis by low-dose alcohol in neonatal rat cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2209-15.
2003: David A Brown; Korinne N Jew; Genevieve C Sparagna; Timothy I Musch; Russell L Moore
Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(6):2510-8.
2002: Diane L M Hickson-Bick; Genevieve C Sparagna; L Maximilian Buja; Jeanie B McMillin
Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H656-64.
2001: Darin Bruce Ostrander; Genevieve C Sparagna; Andrew A Amoscato; Jeanie B McMillin; William Dowhan
Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis.
The Journal of biological chemistry 2001;276(41):38061-7.
2001: Genevieve C Sparagna; Diane L M Hickson-Bick; L Maximilian Buja; Jeanie B McMillin
Fatty acid-induced apoptosis in neonatal cardiomyocytes: redox signaling.
Antioxidants & redox signaling 2001;3(1):71-9.
2000: Genevieve C Sparagna; Diane L M Hickson-Bick; L Maximilian Buja; Jeanie B McMillin
A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis.
American journal of physiology. Heart and circulatory physiology 2000;279(5):H2124-32.
1999: Genevieve C Sparagna; Diane L M Hickson-Bick
Cardiac fatty acid metabolism and the induction of apoptosis.
The American journal of the medical sciences 1999;318(1):15-21.