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Jacques Young

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Veronique Pingault; Odile Vérier-Mine; Yuli Watanabe; Jacques Young; Françoise Archambeaud; Viviane Baral; Jérôme Bertherat; Virginie Bodereau; Asma Chaoui; Catherine Dodé; Delphine Dupin-Deguine; Corinne Fouveaut; Christine Francannet; Michel Goossens; Jean-Pierre Hardelin; François-Joseph Kurtz; Chrystel Leroy; Severine Marcos; Sandrine Marlin; Nadege Bondurand
Loss-of-Function Mutations in SOX10 Cause Kallmann Syndrome with Deafness.
Charlotte Sonigo; Jacques Young; Nadine Binart
[Hyperprolactinemia and infertility: a new physiopathological approach].
Frédéric Brioude; Laurent Combettes; Jérôme Fagart; Bruno Francou; Marc Lombès; Ronan Roussel; say viengchareun; Jacques Young; Jérôme BOULIGAND; Sylvie Brailly-Tabard; Anne Guiochon-Mantel
Two families with normosmic congenital hypogonadotropic hypogonadism and biallelic mutations in KISS1R (KISS1 receptor): clinical evaluation and molecular characterization of a novel mutation.

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All Publications

2013: Veronique Pingault; Odile Vérier-Mine; Yuli Watanabe; Jacques Young; Françoise Archambeaud; Viviane Baral; Jérôme Bertherat; Virginie Bodereau; Asma Chaoui; Catherine Dodé; Delphine Dupin-Deguine; Corinne Fouveaut; Christine Francannet; Michel Goossens; Jean-Pierre Hardelin; François-Joseph Kurtz; Chrystel Leroy; Severine Marcos; Sandrine Marlin; Nadege Bondurand
Loss-of-Function Mutations in SOX10 Cause Kallmann Syndrome with Deafness.
American journal of human genetics 2013;92(5):707-24.
2013: Charlotte Sonigo; Jacques Young; Nadine Binart
[Hyperprolactinemia and infertility: a new physiopathological approach].
Médecine sciences : M/S 2013;29(3):242-4.
2013: Frédéric Brioude; Laurent Combettes; Jérôme Fagart; Bruno Francou; Marc Lombès; Ronan Roussel; say viengchareun; Jacques Young; Jérôme BOULIGAND; Sylvie Brailly-Tabard; Anne Guiochon-Mantel
Two families with normosmic congenital hypogonadotropic hypogonadism and biallelic mutations in KISS1R (KISS1 receptor): clinical evaluation and molecular characterization of a novel mutation.
PloS one 2013;8(1):e53896.
2013: Jacques Young; Javier Tello; Richard A Anderson; Jérôme BOULIGAND; Sylvie Brailly-Tabard; Bruno Francou; Jyothis T George; Anne Guiochon-Mantel; Robert P Millar
Kisspeptin restores pulsatile LH secretion in patients with neurokinin B signaling deficiencies: physiological, pathophysiological and therapeutic implications.
Neuroendocrinology 2013;97(2):193-202.
2012: Nathalie Massin; Yves Morel; Lavinia Vija; Hélène Bry; Frank Claessens; Elisabeth Constancis; Bassam Haddad; Luigi Maione; Jacques Young
Healthy birth after testicular extraction of sperm and ICSI from an azoospermic man with mild androgen insensitivity syndrome caused by an androgen receptor partial loss-of-function mutation.
Clinical endocrinology 2012;77(4):593-8.
2012: Luigi Maione; Patrick Maison; Sylvie Salenave; Jacques Young; Patrick Assayag; Amir Bouchachi; Cyril Garcia; Nozha Kallel; Philippe Chanson
No evidence of a detrimental effect of cabergoline therapy on cardiac valves in patients with acromegaly.
The Journal of clinical endocrinology and metabolism 2012;97(9):E1714-9.
2012: Sylvie Salenave; Sévérine Trabado; Sylvie Brailly-Tabard; Luigi Maione; Jacques Young
Male acquired hypogonadotropic hypogonadism: diagnosis and treatment.
Annales d'endocrinologie 2012;73(2):141-6.
2012: Laure Cazabat; Michèle Bernier; Jérôme BOULIGAND; Stephan Gaillard; Anne Guiochon-Mantel; Fabrice Parker; Sylvie Salenave; Jacques Young; Philippe Chanson
Germline AIP mutations in apparently sporadic pituitary adenomas: prevalence in a prospective single-center cohort of 443 patients.
The Journal of clinical endocrinology and metabolism 2012;97(4):E663-70.
2012: Jacques Young
Approach to the male patient with congenital hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 2012;97(3):707-18.
2012: Claire Bouvattier; Catherine Dodé; Anne Guiochon-Mantel; Luigi Maione; Jérôme BOULIGAND; Jacques Young
Neonatal gonadotropin therapy in male congenital hypogonadotropic hypogonadism.
Nature reviews. Endocrinology 2012;8(3):172-82.
2012: Sophie Mauclère-Denost; Angelo Paci; Martin Schlumberger; Antoine Tabarin; Jacques Young; Isabelle Borget; Philippe Chanson; Desiree Deandreis; Laurence Drouard; sophie leboulleux; Abir Al Ghuzlan; Eric Baudin
High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up.
European journal of endocrinology / European Federation of Endocrine Societies 2012;166(2):261-8.
2012: Javier Tello; Jérôme BOULIGAND; Anne Guiochon-Mantel; Robert P Millar; Claire L Newton; Jacques Young
Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling.
PloS one 2012;7(6):e38456.
2011: J Sarfati; S Trabado; B Betari-Tabet; D Mallet; Y Morel; L Rocher; Jacques Young
Pelvic MRI in a 17-year-old XY girl with 5-alpha reductase deficiency and a homozygous Gly115Asp mutation in SRD5A2.
Annales d'endocrinologie 2011;72(4):310-3.
2011: Séverine Trabado; Luigi Maione; Sylvie Salenave; Stéphanie Baron; Françoise Galland; Hélène Bry-Gauillard; Anne Guiochon-Mantel; Philippe Chanson; Nelly Pitteloud; Antonio Agostino Sinisi; Sylvie Brailly-Tabard; Jacques Young
Estradiol levels in men with congenital hypogonadotropic hypogonadism and the effects of different modalities of hormonal treatment.
Fertility and sterility 2011;95(7):2324-9, 2329.e1-3.
2010: Jérôme BOULIGAND; Cristina Ghervan; Séverine Trabado; Sylvie Brailly-Tabard; Anne Guiochon-Mantel; Jacques Young
Genetics defects in GNRH1: a paradigm of hypothalamic congenital gonadotropin deficiency.
Brain research 2010;1364():3-9.
2010: Michaël Grynberg; Sylvie Salenave; Jacques Young; Philippe Chanson
Female gonadal function before and after treatment of acromegaly.
The Journal of clinical endocrinology and metabolism 2010;95(10):4518-25.
2010: J Sarfati; Jacques Young; S Christin-Maitre
[Obesity and female reproduction].
Annales d'endocrinologie 2010;71 Suppl 1():S49-53.
2010: J Sarfati; Jacques Young; S Christin-Maitre
[The adult ovary is not in sleepiness: major role of forkhead proteins].
Annales d'endocrinologie 2010;71 Suppl 1():S42-8.
2010: sophie leboulleux; D Deandreis; A Al Ghuzlan; Anne Aupérin; D Goéré; Clarisse Dromain; D Elias; Bernard Caillou; Jean-Paul Travagli; T De Baere; Jean Lumbroso; Jacques Young; Martin Schlumberger; Eric Baudin
Adrenocortical carcinoma: is the surgical approach a risk factor of peritoneal carcinomatosis?
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(6):1147-53.
2010: H Bry-Gauillard; S Trabado; Jérôme BOULIGAND; J Sarfati; B Francou; Sylvie Salenave; Philippe Chanson; S Brailly-Tabard; A Guiochon-Mantel; Jacques Young
Congenital hypogonadotropic hypogonadism in females: clinical spectrum, evaluation and genetics.
Annales d'endocrinologie 2010;71(3):158-62.
2010: Philippe Chanson; Sylvie Salenave; Jacques Young
Ovarian dysfunction by activating mutation of GS alpha: McCune-Albright syndrome as a model.
Annales d'endocrinologie 2010;71(3):210-3.
2010: Frédéric Brioude; Jérôme BOULIGAND; Séverine Trabado; Bruno Francou; Sylvie Salenave; Peter Kamenicky; Sylvie Brailly-Tabard; Philippe Chanson; Anne Guiochon-Mantel; Jacques Young
Non-syndromic congenital hypogonadotropic hypogonadism: clinical presentation and genotype-phenotype relationships.
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(5):835-51.
2010: Jacques Young; Jérôme BOULIGAND; Bruno Francou; Marie-Laure Raffin-Sanson; Stéphanie Gaillez; Marc Jeanpierre; Michael Grynberg; Peter Kamenicky; Philippe Chanson; Sylvie Brailly-Tabard; Anne Guiochon-Mantel
TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans.
The Journal of clinical endocrinology and metabolism 2010;95(5):2287-95.
2010: Marie-Laure Kottler; Yen-Yin Chou; Olivier Chabre; Nicolas RICHARD; Camille Polge; Sylvie Brailly-Tabard; Philippe Chanson; Anne Guiochon-Mantel; Ilpo Huhtaniemi; Jacques Young
A new FSHbeta mutation in a 29-year-old woman with primary amenorrhea and isolated FSH deficiency: functional characterization and ovarian response to human recombinant FSH.
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(3):633-41.
2010: Jérôme BOULIGAND; Brigitte Delemer; Annie-Claude Hecart; Geri Meduri; say viengchareun; Larbi Amazit; Séverine Trabado; Bruno Fève; Anne Guiochon-Mantel; Jacques Young; Marc Lombès
Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess.
PloS one 2010;5(10):e13563.
2010: Julie Sarfati; Catherine Dodé; Jacques Young
Kallmann syndrome caused by mutations in the PROK2 and PROKR2 genes: pathophysiology and genotype-phenotype correlations.
Frontiers of hormone research 2010;39():121-32.
2010: Jérôme BOULIGAND; Cristina Ghervan; Anne Guiochon-Mantel; Jacques Young
Hypogonadotropic hypogonadism and GNRH1 mutations in mice and humans.
Frontiers of hormone research 2010;39():111-20.
2009: Philippe Chanson; Sylvie Salenave; Peter Kamenicky; Laure Cazabat; Jacques Young
Pituitary tumours: acromegaly.
Best practice & research. Clinical endocrinology & metabolism 2009;23(5):555-74.
2009: Jérôme BOULIGAND; Cristina Ghervan; Javier Tello; Sylvie Brailly-Tabard; Sylvie Salenave; Philippe Chanson; Marc Lombès; Robert P Millar; Anne Guiochon-Mantel; Jacques Young
Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation.
The New England journal of medicine 2009;360(26):2742-8.
2008: Helene Bry-Gauillard; Geri Meduri; Fadi Abirached; Elisabeth Constancis; Sylvie Brailly; Philippe Chanson; Jacques Young
Primary amenorrhea revealing an occult progesterone-secreting ovarian tumor.
Fertility and sterility 2008;90(4):1198.e1-5.
2008: Sylvie Salenave; Philippe Chanson; Hélène Bry; Michel Pugeat; Sylvie Cabrol; Jean Claude Carel; Arnaud Murat; Pierre Lecomte; Sylvie Brailly; Jean-Pierre Hardelin; Catherine Dodé; Jacques Young
Kallmann's syndrome: a comparison of the reproductive phenotypes in men carrying KAL1 and FGFR1/KAL2 mutations.
The Journal of clinical endocrinology and metabolism 2008;93(3):758-63.
2007: Jacques Young
[Endocrine consequences of hemochromatosis].
Presse médicale (Paris, France : 1983) 2007;36(9 Pt 2):1319-25.
2007: Peter Kamenicky; Laurence Houdoin; Sophie Ferlicot; Sylvie Salenave; Sylvie Brailly; Stéphane Droupy; Geri Meduri; Hironobu Sasano; Takashi Suzuki; Jacques Young; Philippe Chanson
Benign cortisol-secreting adrenocortical adenomas produce small amounts of androgens.
Clinical endocrinology 2007;66(6):778-88.
2006: Françoise Galland; Peter Kamenicky; Hélène Affres; Yves Reznik; Dominique Pontvert; Yves Le Bouc; Jacques Young; Philippe Chanson
McCune-Albright syndrome and acromegaly: effects of hypothalamopituitary radiotherapy and/or pegvisomant in somatostatin analog-resistant patients.
The Journal of clinical endocrinology and metabolism 2006;91(12):4957-61.
2006: Mariagiovanna Filippella; Françoise Galland; Michèle Kujas; Jacques Young; Antongiulio Faggiano; Gaetano Lombardi; Annamaria Colao; Geri Meduri; Philippe Chanson
Pituitary tumour transforming gene (PTTG) expression correlates with the proliferative activity and recurrence status of pituitary adenomas: a clinical and immunohistochemical study.
Clinical endocrinology 2006;65(4):536-43.
2005: Jacques Young; Louise Morbois-Trabut; Béatrice Couzinet; Olivier Lascols; Elisabeth Dion; Véronique Béréziat; Bruno Fève; Isabelle Richard; Jacqueline Capeau; Philippe Chanson; Corinne Vigouroux
Type A insulin resistance syndrome revealing a novel lamin A mutation.
Diabetes 2005;54(6):1873-8.
2005: Jacques Young
[Menopause: a different challenge for each woman].
La Revue du praticien 2005;55(4):361-2.
2005: Jacques Young; Philippe Chanson; Sylvie Salenave; Michèle Noël; Sylvie Brailly; Martín O'Flaherty; Gilbert Schaison; Rodolfo Rey
Testicular anti-mullerian hormone secretion is stimulated by recombinant human FSH in patients with congenital hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 2005;90(2):724-8.
2004: Hélène Bihan; Consuelo Espinosa; Hernan Valdes-Socin; Sylvie Salenave; Jacques Young; Suzanne Levasseur; Patrick Assayag; Albert Beckers; Philippe Chanson
Long-term outcome of patients with acromegaly and congestive heart failure.
The Journal of clinical endocrinology and metabolism 2004;89(11):5308-13.
2004: Sylvie Salenave; Blandine Gatta; Sylvie Pecheur; François San-Galli; André Visot; Pierre Lasjaunias; Patrick Roger; Jérôme Berge; Jacques Young; Antoine Tabarin; Philippe Chanson
Pituitary magnetic resonance imaging findings do not influence surgical outcome in adrenocorticotropin-secreting microadenomas.
The Journal of clinical endocrinology and metabolism 2004;89(7):3371-6.
2003: Jacques Young; Rodolfo Rey; Gilbert Schaison; Philippe Chanson
Hypogonadotropic hypogonadism as a model of post-natal testicular anti-Müllerian hormone secretion in humans.
Molecular and cellular endocrinology 2003;211(1-2):51-4.
2003: Ilinca-Lucia Gussi; Jacques Young; Eric Baudin; Jean-Michel Bidart; Philippe Chanson
Chromogranin A as serum marker of pituitary adenomas.
Clinical endocrinology 2003;59(5):644-8.
2003: Jacques Young
[Prescribing DHEA?].
La Revue du praticien 2003;53(10):1049-53.
2003: Sylvie Salenave; Stéphane Droupy; Jacques Young
[Andropause].
La Revue du praticien 2003;53(9):1015-9.
2001: Béatrice Couzinet; Geri Meduri; M G Lecce; Jacques Young; Sylvie Brailly; Hugues Loosfelt; Edwin Milgrom; Gilbert Schaison
The postmenopausal ovary is not a major androgen-producing gland.
The Journal of clinical endocrinology and metabolism 2001;86(10):5060-6.
2001: Philippe Chanson; F Daujat; Jacques Young; A Bellucci; Michèle Kujas; D Doyon; Gilbert Schaison
Normal pituitary hypertrophy as a frequent cause of pituitary incidentaloma: a follow-up study.
The Journal of clinical endocrinology and metabolism 2001;86(7):3009-15.
2001: Jacques Young; G Schaison
[Intracytoplasmic sperm microinjection].
La Revue du praticien 2001;51(8):817-9.
2000: Jacques Young; Béatrice Couzinet; Philippe Chanson; Sylvie Brailly; E Loumaye; Gilbert Schaison
Effects of human recombinant luteinizing hormone and follicle-stimulating hormone in patients with acquired hypogonadotropic hypogonadism: study of Sertoli and Leydig cell secretions and interactions.
The Journal of clinical endocrinology and metabolism 2000;85(9):3239-44.
2000: Béatrice Couzinet; J Pantel; Philippe Chanson; Jacques Young; Sylvie Brailly; I T Huhtaniemi; Jean-Michel Bidart; Gilbert Schaison
Measurement of plasma free luteinizing hormone beta-subunit in women.
The Journal of clinical endocrinology and metabolism 2000;85(6):2293-8.
1999: Béatrice Couzinet; Jacques Young; Michèle Kujas; Geri Meduri; Sylvie Brailly; J L Thomas; Philippe Chanson; Gilbert Schaison
The antigonadotropic activity of a 19-nor-progesterone derivative is exerted both at the hypothalamic and pituitary levels in women.
The Journal of clinical endocrinology and metabolism 1999;84(11):4191-6.
1999: Jacques Young; Rodolfo Rey; Béatrice Couzinet; Philippe Chanson; Nathalie Josso; Gilbert Schaison
Antimüllerian hormone in patients with hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 1999;84(8):2696-9.
1999: Jacques Young; G Schaison
[Diagnosis and treatment of hypogonadotropism in males and females].
La Revue du praticien 1999;49(12):1283-9.
1999: Béatrice Couzinet; Jacques Young; Sylvie Brailly; Yves Le Bouc; Philippe Chanson; Gilbert Schaison
Functional hypothalamic amenorrhoea: a partial and reversible gonadotrophin deficiency of nutritional origin.
Clinical endocrinology 1999;50(2):229-35.
1998: Philippe Chanson; Nicolas de Roux; Jacques Young; Jean-Michel Bidart; P Jacquet; Micheline Misrahi; Edwin Milgrom; Gilbert Schaison
Absence of activating mutations in the GnRH receptor gene in human pituitary gonadotroph adenomas.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(2):157-60.
1998: Jacques Young; C Deneux; M Grino; C Oliver; Philippe Chanson; Gilbert Schaison
Pitfall of petrosal sinus sampling in a Cushing's syndrome secondary to ectopic adrenocorticotropin-corticotropin releasing hormone (ACTH-CRH) secretion.
The Journal of clinical endocrinology and metabolism 1998;83(2):305-8.
1997: Jacques Young; Béatrice Couzinet; K Nahoul; Sylvie Brailly; Philippe Chanson; Etienne Baulieu; Gilbert Schaison
Panhypopituitarism as a model to study the metabolism of dehydroepiandrosterone (DHEA) in humans.
The Journal of clinical endocrinology and metabolism 1997;82(8):2578-85.
1997: Philippe Chanson; J Pantel; Jacques Young; Béatrice Couzinet; Jean-Michel Bidart; Gilbert Schaison
Free luteinizing-hormone beta-subunit in normal subjects and patients with pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1997;82(5):1397-402.
1996: Béatrice Couzinet; Jacques Young; Sylvie Brailly; Philippe Chanson; J L Thomas; Gilbert Schaison
The antigonadotropic activity of progestins (19-nortestosterone and 19-norprogesterone derivatives) is not mediated through the androgen receptor.
The Journal of clinical endocrinology and metabolism 1996;81(12):4218-23.
1996: Jacques Young; Serdar E Bulun; V Agarwal; Béatrice Couzinet; C R Mendelson; E R Simpson; Gilbert Schaison
Aromatase expression in a feminizing adrenocortical tumor.
The Journal of clinical endocrinology and metabolism 1996;81(9):3173-6.
1996: P Rodien; F Mebarki; Irène Mowszowicz; J L Chaussain; Jacques Young; Yves Morel; Gilbert Schaison
Different phenotypes in a family with androgen insensitivity caused by the same M780I point mutation in the androgen receptor gene.
The Journal of clinical endocrinology and metabolism 1996;81(8):2994-8.
1995: Béatrice Couzinet; Jacques Young; Sylvie Brailly; Philippe Chanson; Gilbert Schaison
Even after priming with ovarian steroids or pulsatile gonadotropin-releasing hormone administration, naltrexone is unable to induce ovulation in women with functional hypothalamic amenorrhea.
The Journal of clinical endocrinology and metabolism 1995;80(7):2102-7.
1994: M Pholsena; Jacques Young; Béatrice Couzinet; Gilbert Schaison
Primary adrenal and thyroid insufficiencies associated with hypopituitarism: a diagnostic challenge.
Clinical endocrinology 1994;40(5):693-5.
1994: Jacques Young; Béatrice Couzinet; M Pholsena; K Nahoul; F Labrie; Gilbert Schaison
Plasma 3 beta-hydroxy-delta 5-steroids in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 1994;78(2):299-304.
1993: Gilbert Schaison; Jacques Young; M Pholsena; K Nahoul; Béatrice Couzinet
Failure of combined follicle-stimulating hormone-testosterone administration to initiate and/or maintain spermatogenesis in men with hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 1993;77(6):1545-9.
1993: Béatrice Couzinet; M Pholsena; Jacques Young; Gilbert Schaison
The impact of a pure anti-androgen (flutamide) on LH, FSH, androgens and clinical status in idiopathic hirsutism.
Clinical endocrinology 1993;39(2):157-62.