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Mauro Gobbini

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Chemicals & Drugs

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Mauro Gobbini; Silvia Armaroli; Leonardo Banfi; Alessandra Benicchio; Giulio Carzana; Patrizia Ferrari; Giuseppe Giacalone; Giuseppe Marazzi; Barbara Moro; Rosella Micheletti; Simona Sputore; Marco Torri; Maria Pia Zappavigna; Alberto Cerri
Novel analogues of Istaroxime, a potent inhibitor of Na(+),K(+)-ATPase: Synthesis, structure-activity relationship and 3D-quantitative structure-activity relationship of derivatives at position 6 on the androstane scaffold.
Mauro Gobbini; Silvia Armaroli; Leonardo Banfi; Alessandra Benicchio; Giulio Carzana; G Fedrizzi; Patrizia Ferrari; Giuseppe Giacalone; Michele Giubileo; Giuseppe Marazzi; Rosella Micheletti; Barbara Moro; Marco Pozzi; Piero Enrico Scotti; Marco Torri; Alberto Cerri
Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationship.
Mauro Gobbini; Alberto Cerri
Digitalis-like compounds: the discovery of the O-aminoalkyloxime group as a very powerful substitute for the unsaturated gamma-butyrolactone moiety.

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All Publications

2010: Mauro Gobbini; Silvia Armaroli; Leonardo Banfi; Alessandra Benicchio; Giulio Carzana; Patrizia Ferrari; Giuseppe Giacalone; Giuseppe Marazzi; Barbara Moro; Rosella Micheletti; Simona Sputore; Marco Torri; Maria Pia Zappavigna; Alberto Cerri
Novel analogues of Istaroxime, a potent inhibitor of Na(+),K(+)-ATPase: Synthesis, structure-activity relationship and 3D-quantitative structure-activity relationship of derivatives at position 6 on the androstane scaffold.
Bioorganic & medicinal chemistry 2010;18(12):4275-99.
2008: Mauro Gobbini; Silvia Armaroli; Leonardo Banfi; Alessandra Benicchio; Giulio Carzana; G Fedrizzi; Patrizia Ferrari; Giuseppe Giacalone; Michele Giubileo; Giuseppe Marazzi; Rosella Micheletti; Barbara Moro; Marco Pozzi; Piero Enrico Scotti; Marco Torri; Alberto Cerri
Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationship.
Journal of medicinal chemistry 2008;51(15):4601-8.
2005: Mauro Gobbini; Alberto Cerri
Digitalis-like compounds: the discovery of the O-aminoalkyloxime group as a very powerful substitute for the unsaturated gamma-butyrolactone moiety.
Current medicinal chemistry 2005;12(20):2343-55.
2003: Sergio De Munari; Alberto Cerri; Mauro Gobbini; Nicoletta Almirante; Leonardo Banfi; Giulio Carzana; Patrizia Ferrari; Giuseppe Marazzi; Rosella Micheletti; Antonio Schiavone; Simona Sputore; Marco Torri; Maria Pia Zappavigna; Piero Melloni
Structure-based design and synthesis of novel potent Na+,K+ -ATPase inhibitors derived from a 5alpha,14alpha-androstane scaffold as positive inotropic compounds.
Journal of medicinal chemistry 2003;46(17):3644-54.
2003: Alberto Cerri; Mauro Gobbini
Simplified digitalis-like compounds acting on Na(+), K(+)-ATPase.
Journal of enzyme inhibition and medicinal chemistry 2003;18(4):289-95.
2001: Mauro Gobbini; Paolo Barassi; Alberto Cerri; Sergio De Munari; G Fedrizzi; M Santagostino; Antonio Schiavone; Marco Torri; Piero Melloni
17 alpha-O-(aminoalkyl)oxime derivatives of 3 beta,14 beta-dihydroxy-5 beta-androstane and 3 beta-hydroxy-14-oxoseco-D-5 beta-androstane as inhibitors of Na(+),K(+)-ATPase at the digitalis receptor.
Journal of medicinal chemistry 2001;44(23):3821-30.
1998: L Quadri; Mauro Gobbini; L Monti
Recent advances in antihypertensive therapy.
Current pharmaceutical design 1998;4(6):489-512.
1998: Mauro Gobbini; Giuseppe Marazzi; Gloria Padoani; L Quadri; L Valentino; Maria Pia Zappavigna; Piero Melloni
Synthesis and biological evaluation of 2-hydroxy derivatives of digitoxigenin and 3-epidigitoxigenin.
Bioorganic & medicinal chemistry 1998;6(10):1889-94.
1998: Sergio De Munari; Paolo Barassi; Alberto Cerri; G Fedrizzi; Mauro Gobbini; M Mabilia; Piero Melloni
A new approach to the design of novel inhibitors of Na+,K+-ATPase: 17alpha-substituted seco-D 5beta-androstane as cassaine analogues.
Journal of medicinal chemistry 1998;41(16):3033-40.
1997: L Quadri; Giuseppe Bianchi; Alberto Cerri; G Fedrizzi; Patrizia Ferrari; Mauro Gobbini; Piero Melloni; S Sputore; Marco Torri
17 beta-(3-furyl)-5 beta-androstane-3 beta, 14 beta, 17 alpha-triol (PST 2238). A very potent antihypertensive agent with a novel mechanism of action.
Journal of medicinal chemistry 1997;40(11):1561-4.
1996: Mauro Gobbini; A Benicchio; G Marazzi; Gloria Padoani; M Torri; Piero Melloni
Digitalis-like compounds: synthesis and biological evaluation of seco-D and D-homo derivatives.
Steroids 1996;61(10):572-82.