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Todd Brusko

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Roniel Cabrera; Lung-Ji Chang; Chen Liu; Miguel Ararat; Mark A Atkinson; Todd Brusko; clive wasserfall; Yiling Xu; David R Nelson
Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma.
James A Thompson; Daniel Perry; Todd Brusko
Autologous regulatory T cells for the treatment of type 1 diabetes.
Michael J Haller; Maigan A Hulme; Kieran M McGrail; Jonathan J Shuster; Theresa M Sumrall; Douglas W Theriaque; Clive H Wasserfall; John R Wingard; Mark A Atkinson; Todd Brusko; Miriam Cintron; Desmond A Schatz
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide.

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2013: Roniel Cabrera; Lung-Ji Chang; Chen Liu; Miguel Ararat; Mark A Atkinson; Todd Brusko; clive wasserfall; Yiling Xu; David R Nelson
Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma.
Cancer immunology, immunotherapy : CII 2013;62(4):737-46.
2012: James A Thompson; Daniel Perry; Todd Brusko
Autologous regulatory T cells for the treatment of type 1 diabetes.
Current diabetes reports 2012;12(5):623-32.
2011: Michael J Haller; Maigan A Hulme; Kieran M McGrail; Jonathan J Shuster; Theresa M Sumrall; Douglas W Theriaque; Clive H Wasserfall; John R Wingard; Mark A Atkinson; Todd Brusko; Miriam Cintron; Desmond A Schatz
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide.
Diabetes care 2011;34(12):2567-9.
2011: Stephanie A McClymont; Amy L Putnam; Michael R Lee; Jonathan Esensten; Weihong Liu; Maigan A Hulme; Ulrich Hoffmüller; Udo Baron; Sven Olek; Jeffrey A Bluestone; Todd Brusko
Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):3918-26.
2011: Eric S Sobel; Westley H Reeves; Ariana N Abid; Todd Brusko; Edward J Butfiloski; Carla Cuda; Wei Hou; Shiwu Li; Laurence Morel
Defective response of CD4(+) T cells to retinoic acid and TGFβ in systemic lupus erythematosus.
Arthritis research & therapy 2011;13(3):R106.
2011: Tatiana N Golovina; Tatiana Mikheeva; Todd Brusko; Bruce R Blazar; Jeffrey A Bluestone; James L Riley
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.
PloS one 2011;6(1):e15868.
2010: Todd Brusko; Richard C Koya; Shirley Zhu; Michael R Lee; Amy L Putnam; Stephanie A McClymont; Michael I Nishimura; Shuhong Han; Lung-Ji Chang; Mark A Atkinson; Antoni Ribas; Jeffrey A Bluestone
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
PloS one 2010;5(7):e11726.
2009: Michael J Haller; clive wasserfall; Kieran M McGrail; Miriam Cintron; Todd Brusko; John R Wingard; Susan S Kelly; Jonathan J Shuster; Mark A Atkinson; Desmond A Schatz
Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.
Diabetes care 2009;32(11):2041-6.
2009: Todd Brusko
Mesenchymal stem cells: a potential border patrol for transplanted islets?
Diabetes 2009;58(8):1728-9.
2008: James F George; Andrea Braun; Todd Brusko; Reny Joseph; Subhashini Bolisetty; clive wasserfall; Mark A Atkinson; Anupam Agarwal; Matthias H Kapturczak
Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells.
The American journal of pathology 2008;173(1):154-60.
2008: Todd Brusko; Amy L Putnam; Jeffrey A Bluestone
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities.
Immunological reviews 2008;223():371-90.
2008: Michael J Haller; Hilla-Lee Viener; clive wasserfall; Todd Brusko; Mark A Atkinson; Desmond A Schatz
Autologous umbilical cord blood infusion for type 1 diabetes.
Experimental hematology 2008;36(6):710-5.
2008: Todd Brusko; Jeffrey Bluestone
Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation.
European journal of immunology 2008;38(4):931-4.
2008: Greg Simon; Matthew Parker; Vijayakumar Ramiya; clive wasserfall; Yanfei Huang; Damien Bresson; R Fletcher Schwartz; Martha Campbell-Thompson; Lauren Tenace; Todd Brusko; Song Xue; Abraham Scaria; Michael Lukason; Scott Eisenbeis; John Williams; Michael J Clare-Salzler; Desmond Schatz; Bruce Kaplan; Matthias von Herrath; Karl L Womer; Mark A Atkinson
Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.
Diabetes 2008;57(2):405-14.
2007: Christopher E Lowe; Jason D Cooper; Todd Brusko; Neil M Walker; Deborah J Smyth; Rebecca Bailey; Kirsi Bourget; Vincent Plagnol; Sarah Field; Mark Atkinson; David G Clayton; Linda S Wicker; John A Todd
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.
Nature genetics 2007;39(9):1074-82.
2007: Todd Brusko; clive wasserfall; Kieran McGrail; Richard Schatz; Hilla Lee Viener; Desmond Schatz; Michael J Haller; Jennifer Rockell; Peter Gottlieb; Michael J Clare-Salzler; Mark Atkinson
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes.
Diabetes 2007;56(3):604-12.
2007: David A Ostrov; C L Barnes; L E Smith; S Binns; Todd Brusko; Aaron Clifford Brown; Patrick Quint; Sally A Litherland; D C Roopenian; Kenneth A Iczkowski
Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex.
Tissue antigens 2007;69(2):181-8.
2007: Todd Brusko; Maigan A Hulme; Courtney B Myhr; Michael J Haller; Mark A Atkinson
Assessing the in vitro suppressive capacity of regulatory T cells.
Immunological investigations 2007;36(5-6):607-28.
2007: Todd Brusko; Mark Atkinson
Treg in type 1 diabetes.
Cell biochemistry and biophysics 2007;48(2-3):165-75.
2006: Philip O Scumpia; Matthew J Delano; Kindra M Kelly; Kerri A O'Malley; Philip A Efron; Priscilla F McAuliffe; Todd Brusko; Ricardo Ungaro; Tolga Barker; James L Wynn; Mark A Atkinson; Westley H Reeves; Michael J Clare Salzler; Lyle L Moldawer
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):7943-9.
2006: Carlos E Araya; clive wasserfall; Todd Brusko; Wei Mu; Mark S Segal; Richard J Johnson; Eduardo H Garin
A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) 2006;21(5):603-10.
2006: Brant R Burkhardt; Scott R Greene; Peter White; Ryan K Wong; John E Brestelli; Jichun Yang; Claudia E Robert; Todd Brusko; clive wasserfall; Jianmei Wu; Mark A Atkinson; Zhiyong Gao; Klaus kaestner; Bryan A Wolf
PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21).
Gene 2006;369():134-41.
2005: Todd Brusko; clive wasserfall; Michael J Clare-Salzler; Desmond A Schatz; Mark A Atkinson
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes.
Diabetes 2005;54(5):1407-14.
2005: Todd Brusko; clive wasserfall; Anupam Agarwal; Matthias H Kapturczak; Mark A Atkinson
An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5181-6.
2004: Michael J Haller; Margaret Samyn; Wilmer W Nichols; Todd Brusko; clive wasserfall; R Fletcher Schwartz; Mark Atkinson; Jonathan J Shuster; Gary L Pierce; Janet H Silverstein
Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes.
Diabetes care 2004;27(12):2911-7.
2004: Sylvaine You; Cyndi Chen; Wen-Hui Lee; Todd Brusko; Mark Atkinson; Chih-Pin Liu
Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6777-85.
2004: Matthias H Kapturczak; clive wasserfall; Todd Brusko; Martha Campbell-Thompson; Tamir M Ellis; Mark A Atkinson; Anupam Agarwal
Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse.
The American journal of pathology 2004;165(3):1045-53.
2004: Alba Morales; clive wasserfall; Todd Brusko; Carolyn Carter; Desmond Schatz; Janet Silverstein; Tamir Ellis; Mark Atkinson
Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes.
Diabetes care 2004;27(8):2010-4.
2004: Dehuang Guo; Manyu Li; Yan Zhang; Ping Yang; Sarah Eckenrode; Diane Hopkins; Weipeng Zheng; Sharad Purohit; Robert Podolsky; Andrew Muir; Jinzhao Wang; Zheng Dong; Todd Brusko; Mark Atkinson; Paolo Pozzilli; Adina Zeidler; Leslie J Raffel; Chaim O Jacob; Yongsoo Park; Manuel Serrano-Rios; Maria T Martinez Larrad; Zixin Zhang; Henri-Jean Garchon; Jean-Francois Bach; Jerome I Rotter; Jin-Xiong She; Cong-Yi Wang
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.
Nature genetics 2004;36(8):837-41.
2004: Y Clare Zhang; Matthew Powers; clive wasserfall; Todd Brusko; Sihong Song; Terence Flotte; Richard O Snyder; Mark Potter; Marda Scott-Jorgensen; Martha Campbell-Thompson; James M Crawford; Harry S Nick; Anupam Agarwal; Tamir M Ellis; Mark A Atkinson
Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunity.
Gene therapy 2004;11(3):233-40.
2003: Kevin S Goudy; Brant R Burkhardt; clive wasserfall; Sihong Song; Martha Campbell-Thompson; Todd Brusko; Matthew A Powers; Michael J Clare-Salzler; Eric S Sobel; Tamir M Ellis; Terence R Flotte; Mark A Atkinson
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2270-8.
2003: Y Clare Zhang; Antonello Pileggi; Anupam Agarwal; R. Damaris Molano; Matthew Powers; Todd Brusko; clive wasserfall; Kevin S Goudy; Elsie Zahr; Raffaella Poggioli; Marda Scott-Jorgensen; Martha Campbell-Thompson; James M Crawford; Harry S Nick; Terence Flotte; Tamir M Ellis; Camillo Ricordi; Luca Inverardi; Mark A Atkinson
Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.
Diabetes 2003;52(3):708-16.