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Giuseppe Zanotti

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X Ray Crystallography

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TOP 3
Md Munan Shaik; Giuseppe Zanotti; Laura Cendron
The crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase (HP0859) from Helicobacter pylori.
Laura Cendron; Ileana Ramazzina; Riccardo Percudani; Claudia Rasore; Giuseppe Zanotti; Rodolfo Berni
Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
Laura Cendron; Daniele Veggi; Enrico Girardi; Giuseppe Zanotti
Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).

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All Publications

2011: Md Munan Shaik; Giuseppe Zanotti; Laura Cendron
The crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase (HP0859) from Helicobacter pylori.
Biochimica et biophysica acta 2011;1814(12):1641-7.
2011: Laura Cendron; Ileana Ramazzina; Riccardo Percudani; Claudia Rasore; Giuseppe Zanotti; Rodolfo Berni
Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
Journal of molecular biology 2011;409(4):504-12.
2011: Laura Cendron; Daniele Veggi; Enrico Girardi; Giuseppe Zanotti
Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 5):531-5.
2011: Laura Cendron; Giuseppe Zanotti
Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island.
The FEBS journal 2011;278(8):1223-31.
2011: Md Munan Shaik; Laura Cendron; Riccardo Percudani; Giuseppe Zanotti
The structure of Helicobacter pylori HP0310 reveals an atypical peptidoglycan deacetylase.
PloS one 2011;6(4):e19207.
2011: Stefania Sarno; Elena Papinutto; C Franchin; Jenny Bain; Martin Elliott; Flavio Meggio; Zygmunt Kazimierczuk; A Orzeszko; Giuseppe Zanotti; Roberto Battistutta; Lorenzo A Pinna
ATP site-directed inhibitors of protein kinase CK2: an update.
Current topics in medicinal chemistry 2011;11(11):1340-51.
2010: Gaia Codolo; Elena Papinutto; Alessandra Polenghi; Mario Milco D'Elios; Giuseppe Zanotti; Marina de Bernard
Structure and immunomodulatory property relationship in NapA of Borrelia burgdorferi.
Biochimica et biophysica acta 2010;1804(12):2191-7.
2010: Ileana Ramazzina; Roberto Costa; Laura Cendron; Rodolfo Berni; Alessio Peracchi; Giuseppe Zanotti; Riccardo Percudani
An aminotransferase branch point connects purine catabolism to amino acid recycling.
Nature chemical biology 2010;6(11):801-6.
2010: Giuseppe Zanotti; Laura Cendron
Functional and structural aspects of Helicobacter pylori acidic stress response factors.
IUBMB life 2010;62(10):715-23.
2010: Lorenza Sisinni; Laura Cendron; Gabriella Favaro; Giuseppe Zanotti
Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding specificity.
The FEBS journal 2010;277(8):1896-905.
2009: Nicola Barison; Laura Cendron; Alberto Trento; Alessandro Angelini; Giuseppe Zanotti
Structural and mutational analysis of TenA protein (HP1287) from the Helicobacter pylori thiamin salvage pathway - evidence of a different substrate specificity.
The FEBS journal 2009;276(21):6227-35.
2009: Laura Cendron; Antonio Trovato; Flavio Seno; Claudia Folli; Beatrice Alfieri; Giuseppe Zanotti; Rodolfo Berni
Amyloidogenic potential of transthyretin variants: insights from structural and computational analyses.
The Journal of biological chemistry 2009;284(38):25832-41.
2009: Mario Milco D'Elios; Gaia Codolo; Amedeo Amedei; Paola Mazzi; Giorgio Berton; Giuseppe Zanotti; Gianfranco Del Prete; Marina de Bernard
Helicobacter pylori, asthma and allergy.
FEMS immunology and medical microbiology 2009;56(1):1-8.
2009: Laura Cendron; Marc Couturier; Alessandro Angelini; Nicola Barison; Markus Stein; Giuseppe Zanotti
The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
Journal of molecular biology 2009;386(1):204-17.
2008: Giuseppe Zanotti; Claudia Folli; Laura Cendron; Beatrice Alfieri; Sonia K Nishida; F Gliubich; Nicola Pasquato; Alessandro Negro; Rodolfo Berni
Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
The FEBS journal 2008;275(23):5841-54.
2008: Gaia Codolo; Amedeo Amedei; Allen C Steere; Elena Papinutto; Andrea Cappon; Alessandra Polenghi; Marisa Benagiano; Silvia Rossi Paccani; vittorio sambri; Gianfranco Del Prete; Cosima T Baldari; Giuseppe Zanotti; Cesare Montecucco; Mario Milco D'Elios; Marina de Bernard
Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis.
Arthritis and rheumatism 2008;58(11):3609-17.
2008: Ileana Ramazzina; Laura Cendron; Claudia Folli; Rodolfo Berni; Daniela Monteverdi; Giuseppe Zanotti; Riccardo Percudani
Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases.
The Journal of biological chemistry 2008;283(34):23295-304.
2008: Andrew Holt; David J Smith; Laura Cendron; Giuseppe Zanotti; Adelio Rigo; Maria Luisa Di Paolo
Multiple binding sites for substrates and modulators of semicarbazide-sensitive amine oxidases: kinetic consequences.
Molecular pharmacology 2008;73(2):525-38.
2007: Laura Cendron; Elisabetta Tasca; Tommaso Seraglio; Anke Seydel; Alessandro Angelini; Roberto Battistutta; Cesare Montecucco; Giuseppe Zanotti
The crystal structure of CagS from the Helicobacter pylori pathogenicity island.
Proteins 2007;69(2):440-3.
2007: Roberto Battistutta; Marco Mazzorana; Laura Cendron; Andrea Bortolato; Stefania Sarno; Zygmunt Kazimierczuk; Giuseppe Zanotti; Stefano Moro; Lorenzo A Pinna
The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules.
Chembiochem : a European journal of chemical biology 2007;8(15):1804-9.
2007: Laura Cendron; Rodolfo Berni; Claudia Folli; Ileana Ramazzina; Riccardo Percudani; Giuseppe Zanotti
The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
The Journal of biological chemistry 2007;282(25):18182-9.
2007: Nicola Pasquato; Rodolfo Berni; Claudia Folli; Beatrice Alfieri; Laura Cendron; Giuseppe Zanotti
Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
Journal of molecular biology 2007;366(3):711-9.
2006: Giuseppe Zanotti; Laura Cendron; Ileana Ramazzina; Claudia Folli; Riccardo Percudani; Rodolfo Berni
Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter.
Journal of molecular biology 2006;363(1):1-9.
2006: Anton Thumiger; Alessandra Polenghi; Elena Papinutto; Roberto Battistutta; Cesare Montecucco; Giuseppe Zanotti
Crystal structure of antigen TpF1 from Treponema pallidum.
Proteins 2006;62(3):827-30.
2006: Nicola Pasquato; Rodolfo Berni; Claudia Folli; Silvia Folloni; Michele Cianci; Sergio Pantano; John R Helliwell; Giuseppe Zanotti
Crystal structure of peach Pru p 3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens.
Journal of molecular biology 2006;356(3):684-94.
2005: Stefania Sarno; Mauro Salvi; Roberto Battistutta; Giuseppe Zanotti; Lorenzo A Pinna
Features and potentials of ATP-site directed CK2 inhibitors.
Biochimica et biophysica acta 2005;1754(1-2):263-70.
2005: Elena Papinutto; Henry J Windle; Laura Cendron; Roberto Battistutta; Dermot Kelleher; Giuseppe Zanotti
Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori.
Biochimica et biophysica acta 2005;1753(2):240-6.
2005: Roberto Battistutta; Marco Mazzorana; Stefania Sarno; Zygmunt Kazimierczuk; Giuseppe Zanotti; Lorenzo A Pinna
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole.
Chemistry & biology 2005;12(11):1211-9.
2005: Michele Lunelli; Maria Luisa Di Paolo; Marianna Biadene; Vito Calderone; Roberto Battistutta; Marina Scarpa; Adelio Rigo; Giuseppe Zanotti
Crystal structure of amine oxidase from bovine serum.
Journal of molecular biology 2005;346(4):991-1004.
2004: Laura Cendron; Anke Seydel; Alessandro Angelini; Roberto Battistutta; Giuseppe Zanotti
Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system.
Journal of molecular biology 2004;340(4):881-9.
2004: Matteo Comin; Concettina Guerra; Giuseppe Zanotti
PROuST: a comparison method of three-dimensional structures of proteins using indexing techniques.
Journal of computational biology : a journal of computational molecular cell biology 2004;11(6):1061-72.
2004: Giuseppe Zanotti; Rodolfo Berni
Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin.
Vitamins and hormones 2004;69():271-95.
2003: Claudia Folli; Nicola Pasquato; Ileana Ramazzina; Roberto Battistutta; Giuseppe Zanotti; Rodolfo Berni
Distinctive binding and structural properties of piscine transthyretin.
FEBS letters 2003;555(2):279-84.
2003: Ambra De Gregorio; Roberto Battistutta; Nicoletta Arena; Manuela Panzalorto; Pietro Francescato; Giovanna Valentini; Giuseppe Bruno; Giuseppe Zanotti
Functional and structural characterization of ovine ornithine transcarbamoylase.
Organic & biomolecular chemistry 2003;1(18):3178-85.
2003: Stefania Sarno; Erika De Moliner; Maria Ruzzene; Mario Angelo Pagano; Roberto Battistutta; Jenny Bain; Doriano Fabbro; Joseph Schoepfer; Matthew Elliott; Pascal Furet; Flavio Meggio; Giuseppe Zanotti; Lorenzo A Pinna
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
The Biochemical journal 2003;374(Pt 3):639-46.
2003: Vito Calderone; Michela Trabucco; Andreja Vujicić; Roberto Battistutta; Giorgio Mario Giacometti; Flora Andreucci; Roberto Barbato; Giuseppe Zanotti
Crystal structure of the PsbQ protein of photosystem II from higher plants.
EMBO reports 2003;4(9):900-5.
2003: Vito Calderone; Rodolfo Berni; Giuseppe Zanotti
High-resolution structures of retinol-binding protein in complex with retinol: pH-induced protein structural changes in the crystal state.
Journal of molecular biology 2003;329(4):841-50.
2003: Vito Calderone; Maria Luisa Di Paolo; Michela Trabucco; Marianna Biadene; Roberto Battistutta; Adelio Rigo; Giuseppe Zanotti
Crystallization and preliminary X-ray data of amine oxidase from bovine serum.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 4):727-9.
2003: Erika De Moliner; Stefano Moro; Stefania Sarno; Giuseppe Zagotto; Giuseppe Zanotti; Lorenzo A Pinna; Roberto Battistutta
Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.
The Journal of biological chemistry 2003;278(3):1831-6.
2003: Giuseppe Zanotti; Concettina Guerra
Is tensegrity a unifying concept of protein folds?
FEBS letters 2003;534(1-3):7-10.
2002: Claudia Folli; Vito Calderone; Ileana Ramazzina; Giuseppe Zanotti; Rodolfo Berni
Ligand binding and structural analysis of a human putative cellular retinol-binding protein.
The Journal of biological chemistry 2002;277(44):41970-7.
2002: Giuseppe Zanotti; Elena Papinutto; William G Dundon; Roberto Battistutta; Michela Seveso; Giuseppe Giudice; Rino Rappuoli; Cesare Montecucco
Structure of the neutrophil-activating protein from Helicobacter pylori.
Journal of molecular biology 2002;323(1):125-30.
2002: Vito Calderone; Claudia Folli; Alessio Marchesani; Rodolfo Berni; Giuseppe Zanotti
Identification and structural analysis of a zebrafish apo and holo cellular retinol-binding protein.
Journal of molecular biology 2002;321(3):527-35.
2002: Vito Calderone; Michela Trabucco; Valentina Menin; Alessandro Negro; Giuseppe Zanotti
Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+.
Biochimica et biophysica acta 2002;1596(2):283-92.
2002: Elena Papinutto; William G Dundon; Nea Pitulis; Roberto Battistutta; Cesare Montecucco; Giuseppe Zanotti
Structure of two iron-binding proteins from Bacillus anthracis.
The Journal of biological chemistry 2002;277(17):15093-8.
2002: Stefania Sarno; Stefano Moro; Flavio Meggio; Giuseppe Zagotto; Diego Dal Ben; Paola Ghisellini; Roberto Battistutta; Giuseppe Zanotti; Lorenzo A Pinna
Toward the rational design of protein kinase casein kinase-2 inhibitors.
Pharmacology & therapeutics 2002;93(2-3):159-68.
2002: William G Dundon; Hiroaki Nishioka; Alessandra Polenghi; Elena Papinutto; Giuseppe Zanotti; Pasqualina Montemurro; Giudice Giuseppe Del; Rino Rappuoli; Cesare Montecucco
The neutrophil-activating protein of Helicobacter pylori.
International journal of medical microbiology : IJMM 2002;291(6-7):545-50.
2001: Giuseppe Zanotti; Vito Calderone; M Beda; G Malpeli; Claudia Folli; Rodolfo Berni
Structure of chicken plasma retinol-binding protein.
Biochimica et biophysica acta 2001;1550(1):64-9.
2001: Roberto Battistutta; Erika De Moliner; Stefania Sarno; Giuseppe Zanotti; Lorenzo A Pinna
Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole.
Protein science : a publication of the Protein Society 2001;10(11):2200-6.
2001: Claudia Folli; Vito Calderone; Simone Ottonello; Angelo Bolchi; Giuseppe Zanotti; Monica Stoppini; Rodolfo Berni
Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3710-5.
2000: Roberto Battistutta; Alessandro Negro; Giuseppe Zanotti
Crystal structure and refolding properties of the mutant F99S/M153T/V163A of the green fluorescent protein.
Proteins 2000;41(4):429-37.
2000: Roberto Battistutta; Stefania Sarno; Erika De Moliner; Elena Papinutto; Giuseppe Zanotti; Lorenzo A Pinna
The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
The Journal of biological chemistry 2000;275(38):29618-22.
2000: Michele Cianci; F Gliubich; Giuseppe Zanotti; Rodolfo Berni
Specific interaction of lipoate at the active site of rhodanese.
Biochimica et biophysica acta 2000;1481(1):103-8.
2000: Roberto Battistutta; Stefania Sarno; Erika De Moliner; Oriano Marin; Olaf-Georg Issinger; Giuseppe Zanotti; Lorenzo A Pinna
The crystal structure of the complex of Zea mays alpha subunit with a fragment of human beta subunit provides the clue to the architecture of protein kinase CK2 holoenzyme.
European journal of biochemistry / FEBS 2000;267(16):5184-90.
2000: Giuseppe Zanotti; A Bassetto; Roberto Battistutta; Claudia Folli; Patrizia Arcidiaco; Monica Stoppini; Rodolfo Berni
Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochimica et biophysica acta 2000;1478(2):232-8.
1999: Giuseppe Zanotti
Muscle fatty acid-binding protein.
Biochimica et biophysica acta 1999;1441(2-3):94-105.
1999: R J Trevino; F Gliubich; Rodolfo Berni; Michele Cianci; JM Chirgwin; Giuseppe Zanotti; Paul M Horowitz
NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
The Journal of biological chemistry 1999;274(20):13938-47.
1999: D Matković-Calogović; Arianna Loregian; M R D'Acunto; Roberto Battistutta; A Tossi; Giorgio Palù; Giuseppe Zanotti
Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
The Journal of biological chemistry 1999;274(13):8764-9.
1999: G Malpeli; Giuseppe Zanotti; F Gliubich; A Rizzotto; S K Nishida; Claudia Folli; Rodolfo Berni
Crystallization and preliminary X-ray data for the human transthyretin-retinol-binding protein (RBP) complex bound to an anti-RBP Fab.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 1):276-8.
1998: Giuseppe Zanotti; M Panzalorto; A Marcato; G Malpeli; Claudia Folli; Rodolfo Berni
Structure of pig plasma retinol-binding protein at 1.65 A resolution.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):1049-52.
1998: F Gliubich; Rodolfo Berni; M Colapietro; L Barba; Giuseppe Zanotti
Structure of sulfur-substituted rhodanese at 1.36 A resolution.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 4):481-6.
1998: Giuseppe Zanotti; G Malpeli; F Gliubich; Claudia Folli; Monica Stoppini; L Olivi; A Savoia; Rodolfo Berni
Structure of the trigonal crystal form of bovine annexin IV.
The Biochemical journal 1998;329 ( Pt 1)():101-6.
1996: F Gliubich; M Gazerro; Giuseppe Zanotti; S Delbono; G Bombieri; Rodolfo Berni
Active site structural features for chemically modified forms of rhodanese.
The Journal of biological chemistry 1996;271(35):21054-61.
1995: Giuseppe Zanotti; M R D'Acunto; G Malpeli; Claudia Folli; Rodolfo Berni
Crystal structure of the transthyretin--retinoic-acid complex.
European journal of biochemistry / FEBS 1995;234(2):563-9.
1994: Alessandro Vindigni; Vincenzo De Filippis; Giuseppe Zanotti; C Visco; G Orsini; Angelo Fontana
Probing the structure of hirudin from Hirudinaria manillensis by limited proteolysis. Isolation, characterization and thrombin-inhibitory properties of N-terminal fragments.
European journal of biochemistry / FEBS 1994;226(2):323-33.
1994: Giuseppe Zanotti; M Marcello; G Malpeli; Claudia Folli; Geppo Sartori; Rodolfo Berni
Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
The Journal of biological chemistry 1994;269(47):29613-20.
1994: Giuseppe Zanotti; L Feltre; Paola Spadon
A possible route for the release of fatty acid from fatty acid-binding protein.
The Biochemical journal 1994;301 ( Pt 2)():459-63.
1994: Elisabetta Schievano; D Quarzago; Paola Spadon; H L Monaco; Giuseppe Zanotti; Evaristo Peggion
Conformational and binding properties of chicken liver basic fatty acid binding protein in solution.
Biopolymers 1994;34(7):879-87.
1993: Giuseppe Zanotti; G Malpeli; Rodolfo Berni
The interaction of N-ethyl retinamide with plasma retinol-binding protein (RBP) and the crystal structure of the retinoid-RBP complex at 1.9-A resolution.
The Journal of biological chemistry 1993;268(33):24873-9.
1993: Giuseppe Zanotti; Rodolfo Berni; H L Monaco
Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein.
The Journal of biological chemistry 1993;268(15):10728-38.
1993: Giuseppe Zanotti; Simone Ottonello; Rodolfo Berni; H L Monaco
Crystal structure of the trigonal form of human plasma retinol-binding protein at 2.5 A resolution.
Journal of molecular biology 1993;230(2):613-24.
1992: M C Zapponi; Giuseppe Zanotti; Monica Stoppini; Rodolfo Berni
The primary structure of piscine (Oncorhynchus mykiss) retinol-binding protein and a comparison with the three-dimensional structure of mammalian retinol-binding protein.
European journal of biochemistry / FEBS 1992;210(3):937-43.
1992: Giuseppe Zanotti; Giovanna Scapin; Paola Spadon; J H Veerkamp; James C Sacchettini
Three-dimensional structure of recombinant human muscle fatty acid-binding protein.
The Journal of biological chemistry 1992;267(26):18541-50.
1992: H L Monaco; Giuseppe Zanotti
Three-dimensional structure and active site of three hydrophobic molecule-binding proteins with significant amino acid sequence similarity.
Biopolymers 1992;32(4):457-65.
1990: Giovanna Scapin; Paola Spadon; M Mammi; Giuseppe Zanotti; H L Monaco
Crystal structure of chicken liver basic fatty acid-binding protein at 2.7 A resolution.
Molecular and cellular biochemistry 1990;98(1-2):95-9.
1990: Rodolfo Berni; Monica Stoppini; M C Zapponi; M L Meloni; H L Monaco; Giuseppe Zanotti
The bovine plasma retinol-binding protein. Amino acid sequence, interaction with transthyretin, crystallization and preliminary X-ray data.
European journal of biochemistry / FEBS 1990;192(2):507-13.
1988: Giovanna Scapin; Paola Spadon; L Pengo; M Mammi; Giuseppe Zanotti; H L Monaco
Chicken liver basic fatty acid-binding protein (pI = 9.0). Purification, crystallization and preliminary X-ray data.
FEBS letters 1988;240(1-2):196-200.
1987: H L Monaco; Giuseppe Zanotti; Paola Spadon; M Bolognesi; Lindsay Sawyer; E E Eliopoulos
Crystal structure of the trigonal form of bovine beta-lactoglobulin and of its complex with retinol at 2.5 A resolution.
Journal of molecular biology 1987;197(4):695-706.
1984: D Zanette; H L Monaco; Giuseppe Zanotti; Paola Spadon
Crystallization of hen eggwhite riboflavin-binding protein.
Journal of molecular biology 1984;180(4):1185-7.
1984: H L Monaco; Giuseppe Zanotti; Simone Ottonello; Rodolfo Berni
Crystallization of human plasma apo-retinol-binding protein.
Journal of molecular biology 1984;178(2):477-9.
1983: Simone Ottonello; G Maraini; M Mammi; H L Monaco; Paola Spadon; Giuseppe Zanotti
Crystallization and preliminary X-ray data of human plasma retinol-binding protein.
Journal of molecular biology 1983;163(4):679-81.