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Gérard Lizard

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Luigi Iuliano; Gérard Lizard
Oxysterols and related sterols in chemistry, biology and medicine: a dynamic European field of investigation.
Thomas Nury; Jean-Marc Riedinger; Mohammad Samadi; Alexis Varin; Anne Vejux; Amira Zarrouk; Mohamed Boumhras; Tatiana Lopez; David Masson; Gérard Lizard
Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α-hydroxycholesterol, on oligodendrocytes: effects on cell growth and viability, oxidative and inflammatory status.
Nicolas Isambert; Jean-François Jeannin; Gérard Lizard; Catherine Paul; Kevin Ragot; Sylvie Zanetta; Jacques Bauer; Christophe Ferrand; Pierre Fumoleau; Marc Bardou
Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors.

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All Publications

2013: Luigi Iuliano; Gérard Lizard
Oxysterols and related sterols in chemistry, biology and medicine: a dynamic European field of investigation.
Biochimie 2013;95(3):445-7.
2013: Thomas Nury; Jean-Marc Riedinger; Mohammad Samadi; Alexis Varin; Anne Vejux; Amira Zarrouk; Mohamed Boumhras; Tatiana Lopez; David Masson; Gérard Lizard
Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α-hydroxycholesterol, on oligodendrocytes: effects on cell growth and viability, oxidative and inflammatory status.
Biochimie 2013;95(3):518-30.
2013: Nicolas Isambert; Jean-François Jeannin; Gérard Lizard; Catherine Paul; Kevin Ragot; Sylvie Zanetta; Jacques Bauer; Christophe Ferrand; Pierre Fumoleau; Marc Bardou
Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors.
BMC cancer 2013;13():172.
2012: Flore Geillon; Catherine Gondcaille; Gérard Lizard; Doriane Trompier; Stéphane Savary
[Peroxisomal ABC transporters and X-linked adrenoleukodystrophy].
Médecine sciences : M/S 2012;28(12):1087-94.
2012: Stéphane Savary; Doriane Trompier; Pierre Andréoletti; Jean Demarquoy; Françoise Le Borgne; Gérard Lizard
Fatty acids - induced lipotoxicity and inflammation.
Current drug metabolism 2012;13(10):1358-70.
2012: Romain Guerreiro; Gérard Lizard; Kévin Ragot; Jerome Bellenger; Anne A Besson; Bruno Faivre; Gabriele Sorci
Correlational selection on pro- and anti-inflammatory effectors.
Evolution; international journal of organic evolution 2012;66(11):3615-23.
2012: mauhamad baarine; G Bessede; Mustapha Cherkaoui Malki; Z Kattan; T Nury; K Ragot; Jean-Marc Riedinger; Stéphane Savary; Doriane Trompier; Anne Vejux; A Zarrouk; P Andréoletti; Anne Athias; Gérard Lizard
Evidence of oxidative stress in very long chain fatty acid--treated oligodendrocytes and potentialization of ROS production using RNA interference-directed knockdown of ABCD1 and ACOX1 peroxisomal proteins.
Neuroscience 2012;213():1-18.
2012: H I El Hajj; S Kersten; Gérard Lizard; Stéphane Mandard; K Ragot; Janardan K Reddy; A Vluggens; R J A Wanders; H R Waterham; P Andreoletti; Mustapha Cherkaoui Malki
The inflammatory response in acyl-CoA oxidase 1 deficiency (pseudoneonatal adrenoleukodystrophy).
Endocrinology 2012;153(6):2568-75.
2012: Anne Vejux; Amira Zarrouk; Lucy Martine; Thomas Montange; Jean-Marc Riedinger; Gérard Lizard
Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols.
Journal of agricultural and food chemistry 2012;60(16):4060-6.
2012: mauhamad baarine; Marc Bardou; Emmanuelle C Genin; Zilal Kattan; Franck Ménétrier; Thomas Nury; Kévin Ragot; Jean-Marc Riedinger; Pierre Andreoletti; Anne Athias; Gérard Lizard
Incidence of Abcd1 level on the induction of cell death and organelle dysfunctions triggered by very long chain fatty acids and TNF-α on oligodendrocytes and astrocytes.
Neurotoxicology 2012;33(2):212-28.
2012: Jean-Pierre Rifler; Philippe d'Athis; Dominique Delmas; Philippe Durand; Bernard Hudelot; Emeric Limagne; Gérard Lizard; Fanny Lorcerie; Frédéric Mazué; Michel Prost; Kévin Ragot; Jean-Marc Riedinger; Norbert Latruffe
A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients.
Molecular nutrition & food research 2012;56(2):345-51.
2012: Edmond Kahn; Nicolas Tissot; Claude-Marie Bachelet; Mohamed Boumhras; Aurélien Dauphin; Perrine Frere; Frédérique Frouin; Gérard Lizard
Fluorescence excitation analysis by two-photon confocal laser scanning microscopy: a new method to identify fluorescent nanoparticles on histological tissue sections.
International journal of nanomedicine 2012;7():5545-54.
2012: Amira Zarrouk; Thomas Nury; Jean-Marc Riedinger; Anne Vejux; Mustapha Cherkaoui Malki; Hammam I El Hajj; Madouda Haddad; Mohamed Hammami; Gérard Lizard
Induction of mitochondrial changes associated with oxidative stress on very long chain fatty acids (C22:0, C24:0, or C26:0)-treated human neuronal cells (SK-NB-E).
Oxidative medicine and cellular longevity 2012;2012():623257.
2012: Gérard Lizard; Olivier Rouaud; Mustapha Cherkaoui Malki; Jean Demarquoy; Luigi Iuliano
Potential roles of peroxisomes in Alzheimer's disease and in dementia of the Alzheimer's type.
Journal of Alzheimer's disease : JAD 2012;29(2):241-54.
2011: Nicolas Coant; Jacques Devière; Magali Fasseu; Sonia Gandoura; Thierry Gustot; Didier Lebrec; Philippe Lettéron; Gérard Lizard; Eric Ogier-Denis; Romy Ouziel; Kévin Ragot; Marika Simon-Rudler; Zéra Tellier; Dominique Thabut; Waël Abdel-Razek; Richard Moreau
Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis.
Journal of hepatology 2011;55(4):784-93.
2011: Gerd Schmitz; Gérard Lizard; Luigi Iuliano
Special issue to LipidomicNet and ENOR Joint Workshop (19-20 November 2010; Munich, Germany) "Analysis and function of oxysterols and other regulatory and lipotoxic molecular lipid species".
Chemistry and physics of lipids 2011;164(6):409-10.
2011: Kévin Ragot; Thomas Nury; Anne Athias; mauhamad baarine; Dominique Delmas; Gérard Lizard
α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes.
Chemistry and physics of lipids 2011;164(6):469-78.
2011: Didier Colin; Anne Athias; Philippe Gambert; Aziz Hichami; Arnaud Jacquel; Sylvie Jeanningros; Norbert Latruffe; Emeric Limagne; Gérard Lizard; Eric Solary; Dominique Delmas
Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Cancer prevention research (Philadelphia, Pa.) 2011;4(7):1095-106.
2011: mauhamad baarine; Sijo Joseph Thandapilly; Xavier Lieben Louis; Frédéric Mazué; Liping Yu; Dominique Delmas; Thomas Netticadan; Gérard Lizard; Norbert Latruffe
Pro-apoptotic versus anti-apoptotic properties of dietary resveratrol on tumoral and normal cardiac cells.
Genes & nutrition 2011;6(2):161-9.
2011: Edmond Kahn; mauhamad baarine; Aurélien Dauphin; Kévin Ragot; Nicolas Tissot; Alix Seguin; Franck Ménétrier; Zilal Kattan; Claude-Marie Bachelet; Frédérique Frouin; Gérard Lizard
Impact of 7-ketocholesterol and very long chain fatty acids on oligodendrocyte lipid membrane organization: evaluation via LAURDAN and FAMIS spectral image analysis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(4):293-305.
2011: Marc Labenne; Gérard Lizard; Thomas Montange; Francesco Bonsante; Cyril Ferdynus; Silvia Iacobelli; Jean-Bernard Gouyon
A clinic-biological score for diagnosing early-onset neonatal infection in critically ill preterm infants.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2011;12(2):203-9.
2011: Anne Vejux; Mohammad Samadi; Gérard Lizard
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments.
Journal of ophthalmology 2011;2011():471947.
2010: Jean-Francis Maillefert; Xavier Puéchal; Géraldine Falgarone; Gérard Lizard; Paul Ornetti; Elisabeth Solau; Virginie Legré; Frédéric Lioté; Jean Sibilia; Jacques Morel; Marc Maynadié
Prediction of response to disease modifying antirheumatic drugs in rheumatoid arthritis.
Joint, bone, spine : revue du rhumatisme 2010;77(6):558-63.
2010: B Dugas; S Charbonnier; mauhamad baarine; K Ragot; Dominique Delmas; Franck Ménétrier; Jeannine Lherminier; Laure Malvitte; T Khalfaoui; Alain Bron; Catherine Creuzot-Garcher; Norbert Latruffe; Gérard Lizard
Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.
European journal of nutrition 2010;49(7):435-46.
2010: Edmond Kahn; mauhamad baarine; Sophie Pelloux; Jean-Marc Riedinger; Frédérique Frouin; Yves Tourneur; Gérard Lizard
Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells.
International journal of nanomedicine 2010;5():185-95.
2009: Edmond Kahn; Sophie Pelloux; mauhamad baarine; Taoufik Khalfaoui; Kévin Ragot; Frédérique Frouin; Jean-Marc Riedinger; Yves Tourneur; Gérard Lizard
Analysis of the capture and influence of nanoparticles on the cytotoxic effects of 7-ketocholesterol on cardiac cells: investigation by flow cytometry and by dynamic and spectral imaging microscopy associated with factor analysis of medical image sequences.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2009;31(6):380-94.
2009: Corinne Joffre; M Souchier; L Leclere; B Buteau; S Grégoire; Gérard Lizard; T Montange; Niyazi Acar; Alain Bron; Catherine Creuzot-Garcher; Y Diebold; Lionel Bretillon
Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells.
The British journal of ophthalmology 2009;93(10):1391-5.
2009: Didier Colin; Amandine Gimazane; Gérard Lizard; Jean-Claude Izard; Eric Solary; Norbert Latruffe; Dominique Delmas
Effects of resveratrol analogs on cell cycle progression, cell cycle associated proteins and 5fluoro-uracil sensitivity in human derived colon cancer cells.
International journal of cancer. Journal international du cancer 2009;124(12):2780-8.
2009: Carole Elbim; Gérard Lizard
Flow cytometric investigation of neutrophil oxidative burst and apoptosis in physiological and pathological situations.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(6):475-81.
2009: Anne Vejux; Gérard Lizard
Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.
Molecular aspects of medicine 2009;30(3):153-70.
2009: Stéphanie Lemaire-Ewing; Arnaud Berthier; Marie Charlotte Royer; Emmanuelle Logette; Laurent Corcos; André Bouchot; Serge Monier; Céline Prunet; Magalie Raveneau; Cédric Rébé; Catherine Desrumaux; Gérard Lizard; Dominique Néel
7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent.
Cell biology and toxicology 2009;25(2):127-39.
2009: Gérard Lizard
Diagnosing HIV infection using flow cytometry: From antigenic analyses to a specifically dedicated bead-based assay to measure viral load.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(3):172-4.
2009: Anne Vejux; Stéphane Guyot; Thomas Montange; Jean-Marc Riedinger; Edmond Kahn; Gérard Lizard
Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.
The Journal of nutritional biochemistry 2009;20(1):45-61.
2008: Gérard Lizard
Phytosterols: to be or not to be toxic; that is the question.
The British journal of nutrition 2008;100(6):1150-1.
2008: Didier Colin; Allan Lancon; Dominique Delmas; Gérard Lizard; Jessica Abrossinow; Edmond Kahn; Brigitte Jannin; Norbert Latruffe
Antiproliferative activities of resveratrol and related compounds in human hepatocyte derived HepG2 cells are associated with biochemical cell disturbance revealed by fluorescence analyses.
Biochimie 2008;90(11-12):1674-84.
2008: Laure Malvitte; Thomas Montange; Anne Vejux; Corinne Joffre; Alain Bron; Catherine Creuzot-Garcher; Gérard Lizard
Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol.
Current eye research 2008;33(9):769-81.
2008: Anna-Kristina Marel; Gérard Lizard; Jean-Claude Izard; Norbert Latruffe; Dominique Delmas
Inhibitory effects of trans-resveratrol analogs molecules on the proliferation and the cell cycle progression of human colon tumoral cells.
Molecular nutrition & food research 2008;52(5):538-48.
2008: Taoufik Khalfaoui; Gérard Lizard; Amel Ouertani-Meddeb
Adhesion molecules (ICAM-1 and VCAM-1) and diabetic retinopathy in type 2 diabetes.
Journal of molecular histology 2008;39(2):243-9.
2007: Gérard Lizard
Flow cytometry analyses and bioinformatics: interest in new softwares to optimize novel technologies and to favor the emergence of innovative concepts in cell research.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(9):646-7.
2007: Anne Vejux; Gérard Lizard; Yves Tourneur; Jean-Marc Riedinger; Frédérique Frouin; Edmond Kahn
Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(8):550-62.
2007: Anne Vejux; Edmond Kahn; Franck Ménétrier; Thomas Montange; Jeannine Lherminier; Jean-Marc Riedinger; Gérard Lizard
Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation.
Histochemistry and cell biology 2007;127(6):609-24.
2007: Allan Lancon; Nathalie Hanet; Brigitte Jannin; Dominique Delmas; Jean-Marie Heydel; Gérard Lizard; Marie-Christine Chagnon; Yves Artur; Norbert Latruffe
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(5):699-703.
2007: Corinne Joffre; Laurent Leclère; Bénédicte Buteau; Lucy Martine; Stéphanie Cabaret; Laure Malvitte; Niyazi Acar; Gérard Lizard; Alain Bron; Catherine Creuzot-Garcher; Lionel Bretillon
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
Current eye research 2007;32(3):271-80.
2007: Laure Malvitte; Thomas Montange; Anne Vejux; Christophe Baudouin; Alain M Bron; Catherine Creuzot-Garcher; Gérard Lizard
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.
The British journal of ophthalmology 2007;91(1):29-32.
2006: Edmond Kahn; Franck Ménétrier; Anne Vejux; Thomas Montange; Dominique Dumas; Jean-Marc Riedinger; Frédérique Frouin; Yves Tourneur; Frédéric Brau; Jean-François Stoltz; Gérard Lizard
Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2006;28(6):316-30.
2006: Gérard Lizard
Oxysterol mixtures, a promising approach to investigate the biological effects of oxysterols: a commentary on "Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects," by Larsson, Baird, Diinga Nyhalah, Yuan, and Li.
Free radical biology & medicine 2006;41(6):872-3.
2006: Cécile Guichard; Eric Pedruzzi; Michèle Fay; Jean-Claude Marie; Françoise Braut-Boucher; Fanny Daniel; Alain Grodet; Marie-Anne Gougerot-Pocidalo; Eric Chastre; Larissa Kotelevets; Gérard Lizard; Alain Vandewalle; Fathi Driss; Eric Ogier-Denis
Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.
Carcinogenesis 2006;27(9):1812-27.
2006: Laure Malvitte; Thomas Montange; Corinne Joffre; Anne Vejux; C Maïza; Alain Bron; Catherine Creuzot-Garcher; Gérard Lizard
[Analogies between atherosclerosis and age-related maculopathy: expected roles of oxysterols].
Journal français d'ophtalmologie 2006;29(5):570-8.
2006: Céline Prunet; Thomas Montange; Anne Véjux; Aline Laubriet; Jean-François Rohmer; Jean-Marc Riedinger; Anne Athias; Stéphanie Lemaire-Ewing; Dominique Néel; Jean Michel Petit; Eric Steinmetz; Roger Brenot; Philippe Gambert; Gérard Lizard
Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(5):359-73.
2006: Edmond Kahn; Anne Vejux; Franck Ménétrier; Christophe Maiza; Arlette Hammann; Anabelle Sequeira-Le Grand; Frédérique Frouin; Yves Tourneur; Frédéric Brau; Jean-Marc Riedinger; Eric Steinmetz; Andrew Todd-Pokropek; Gérard Lizard
Analysis of CD36 expression on human monocytic cells and atherosclerotic tissue sections with quantum dots: investigation by flow cytometry and spectral imaging microscopy.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2006;28(1):14-26.
2006: Céline Prunet; Jean Michel Petit; A Ecarnot-Laubriet; Anne Athias; C Miguet-Alfonsi; Jean-François Rohmer; Eric Steinmetz; Dominique Néel; Philippe Gambert; Gérard Lizard
High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy.
Pathologie-biologie 2006;54(1):22-32.
2005: Arnaud Berthier; Stéphanie Lemaire-Ewing; Céline Prunet; Thomas Montange; Anne Vejux; Jean-Paul Pais de Barros; Serge Monier; Philippe Gambert; Gérard Lizard; Dominique Néel
7-Ketocholesterol-induced apoptosis. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways.
The FEBS journal 2005;272(12):3093-104.
2005: Anne Vejux; Edmond Kahn; Dominique Dumas; Ginette Bessède; Franck Ménétrier; Anne Athias; Jean-Marc Riedinger; Frédérique Frouin; Jean-François Stoltz; Eric Ogier-Denis; Andrew Todd-Pokropek; Gérard Lizard
7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2005;64(2):87-100.
2005: Stéphanie Lemaire-Ewing; Céline Prunet; Thomas Montange; Anne Vejux; Arnaud Berthier; Ginette Bessède; Laurent Corcos; Philippe Gambert; Dominique Néel; Gérard Lizard
Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols.
Cell biology and toxicology 2005;21(2):97-114.
2005: Céline Prunet; Stéphanie Lemaire-Ewing; Franck Ménétrier; Dominique Néel; Gérard Lizard
Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study.
Journal of biochemical and molecular toxicology 2005;19(5):311-26.
2004: Edmond Kahn; Anne Vejux; Dominique Dumas; Thomas Montange; Frédérique Frouin; Vincent Robert; Jean-Marc Riedinger; Jean-François Stoltz; Philippe Gambert; Andrew Todd-Pokropek; Gérard Lizard
FRET multiphoton spectral imaging microscopy of 7-ketocholesterol and Nile Red in U937 monocytic cells loaded with 7-ketocholesterol.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2004;26(6):304-13.
2004: Eric Pedruzzi; Cécile Guichard; Véronique Ollivier; Fathi Driss; Michèle Fay; Céline Prunet; Jean-Claude Marie; Cécile Pouzet; Mohammad Samadi; Carole Elbim; Yvonne O'Dowd; Marcelle Bens; Alain Vandewalle; Marie-Anne Gougerot-Pocidalo; Gérard Lizard; Eric Ogier-Denis
NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells.
Molecular and cellular biology 2004;24(24):10703-17.
2004: Edmond Kahn; Gérard Lizard; Dominique Dumas; Frédérique Frouin; Franck Ménétrier; Jean-François Stoltz; Andrew Todd-Pokropek
Analysis of fluorescent MRI contrast agent behavior in the liver and thoracic aorta of mice.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2004;26(4):233-8.
2004: Arnaud Berthier; Stéphanie Lemaire-Ewing; Céline Prunet; Serge Monier; Anne Athias; Ginette Bessède; Jean-Paul Pais de Barros; Aline Laubriet; Philippe Gambert; Gérard Lizard; Dominique Néel
Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis.
Cell death and differentiation 2004;11(8):897-905.
2004: Edmond Kahn; Anne Vejux; Gérard Lizard; Ginette Bessède; Frédérique Frouin; Céline Prunet; Jean-Claude Bernengo; Frédéric Brau; Andrew Todd-Pokropek; Philippe Gambert
Analysis of the fluorescence of monodansylcadaverine-positive cytoplasmic structures during 7-ketocholesterol-induced cell death.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2004;26(1):47-56.
2004: Laurence Duvillard; Philippe Gambert; Gérard Lizard
[Flow cytometric study of low density lipoprotein receptors: biological and clinical interest].
Annales de biologie clinique 2004;62(1):87-91.
2004: Gérard Lizard; Serge Monier; Céline Prunet; Laurence Duvillard; Philippe Gambert
[Microspheres, nanospheres and flow cytometry: from cellular to molecular analysis].
Annales de biologie clinique 2004;62(1):47-52.
2003: Gérard Lizard; Laurence Duvillard; Niels Wedemeyer; C Muller; F Ghiringhelli; A Cesbron; P Poncelet; F Gallet; E Kahn; Philippe Gambert; Wolfgang Göhde
[Microbeads, nanobeads and cytometry: applications to the analysis and purification of cells and biomolecules].
Pathologie-biologie 2003;51(7):418-27.
2003: Gérard Lizard
[Flow cytometry, nanobeads and microbeads: powerful tools for multiplexed molecular analyses].
Pathologie-biologie 2003;51(7):416-7.
2003: Laurence Duvillard; Emmanuel FLORENTIN; Gérard Lizard; Jean Michel Petit; Françoise Galland; Serge Monier; Philippe Gambert; Bruno Vergès
Cell surface expression of LDL receptor is decreased in type 2 diabetic patients and is normalized by insulin therapy.
Diabetes care 2003;26(5):1540-4.
2003: Serge Monier; Mohammad Samadi; Céline Prunet; Mikeäl Denance; Aline Laubriet; Anne Athias; Arnaud Berthier; Eric Steinmetz; Günter Jürgens; Anne Nègre-Salvayre; Ginette Bessède; Stéphanie Lemaire-Ewing; Dominique Néel; Philippe Gambert; Gérard Lizard
Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate.
Biochemical and biophysical research communications 2003;303(3):814-24.
2003: Jean-Marie Zahm; Sonia Baconnais; Serge Monier; Noël Bonnet; Ginette Bessède; Philippe Gambert; Edith Puchelle; Gérard Lizard
Chronology of cellular alterations during 7-ketocholesterol-induced cell death on A7R5 rat smooth muscle cells: analysis by time lapse-video microscopy and conventional fluorescence microscopy.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;52(2):57-69.
2003: Edmond Kahn; C Tessier; Gérard Lizard; Anne Petiet; Jean-Claude Bernengo; Dominique Coulaud; C Fourré; Frédérique Frouin; Olivier Clément; J-R Jourdain; Etienne Delain; Françoise Guiraud-Vitaux; Nicole Colas-Linhart; Nathalie Siauve; Charles A Cuenod; Guy Frija; Andrew Todd-Pokropek
Analysis of the distribution of MRI contrast agents in the livers of small animals by means of complementary microscopies.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;51(2):97-106.
2002: Edmond Kahn; Gérard Lizard; Serge Monier; Ginette Bessède; Frédérique Frouin; Philippe Gambert; Andrew Todd-Pokropek
Flow cytometry and factor analysis evaluation of confocal image sequences of morphologic and functional changes occurring at the mitochondrial level during 7-ketocholesterol-induced cell death.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2002;24(6):355-62.
2002: Valérie Deckert; Linda Duverneuil; Sandrine Poupon; Serge Monier; Naig Le Guern; Gérard Lizard; David Masson; Laurent Lagrost
The impairment of endothelium-dependent arterial relaxation by 7-ketocholesterol is associated with an early activation of protein kinase C.
British journal of pharmacology 2002;137(5):655-62.
2002: Edmond Kahn; Christine Tessier; Gérard Lizard; Anne Petiet; Frédéric Brau; Olivier Clément; Frédérique Frouin; Jean-René Jourdain; Françoise Guiraud-Vitaux; Nicole Colas-Linhart; Nathalie Siauve; Charles A Cuenod; Guy Frija; Andrew Todd-Pokropek
Distribution of injected MRI contrast agents in mouse livers studied by confocal and SIMS microscopy.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2002;24(5):295-302.
2002: Carole Miguet-Alfonsi; Céline Prunet; Serge Monier; Ginette Bessède; Stéphanie Lemaire-Ewing; Arnaud Berthier; Franck Ménétrier; Dominique Néel; Philippe Gambert; Gérard Lizard
Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals.
Biochemical pharmacology 2002;64(3):527-41.
2002: Jean Michel Petit; Michel Duong; Laurence Duvillard; Emmanuel FLORENTIN; Henri Portier; Gérard Lizard; Jean-Marcel Brun; Philippe Gambert; Bruno Verges
LDL-receptors expression in HIV-infected patients: relations to antiretroviral therapy, hormonal status, and presence of lipodystrophy.
European journal of clinical investigation 2002;32(5):354-9.
2002: Maria-Cristina Plotkowski; Helvécio C C Póvoa; Jean-Marie Zahm; Gérard Lizard; Geraldo Pereira; Jean-Marie Tournier; Edith Puchelle
Early mitochondrial dysfunction, superoxide anion production, and DNA degradation are associated with non-apoptotic death of human airway epithelial cells induced by Pseudomonas aeruginosa exotoxin A.
American journal of respiratory cell and molecular biology 2002;26(5):617-26.
2001: G Bessede; C Miguet; Philippe Gambert; D Neel; Gérard Lizard
Efficiency of homocysteine plus copper in inducing apoptosis is inversely proportional to gamma-glutamyl transpeptidase activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):1927-40.
2001: Olivier Sordet; Cédric Rébé; I Leroy; Jean-Marie Bruey; Carmen Garrido; C Miguet; Gérard Lizard; Stéphanie Plenchette; Laurent Corcos; Eric Solary
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.
Blood 2001;97(12):3931-40.
2001: Edmond Kahn; Gérard Lizard; Frédérique Frouin; Catherine Souchier; Jean-Claude Bernengo; H Siitari; Charles A Cuenod; Olivier Clément; Guy Frija; Philippe Gambert; Andrew Todd-Pokropek
Confocal image characterization of human papillomavirus DNA sequences revealed with Eu in HeLa cell nuclei stained with Hoechst 33342.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2001;23(2):101-8.
2001: Edmond Kahn; Gérard Lizard; Frédérique Frouin; Jean-Claude Bernengo; Catherine Souchier; Ginette Bessède; Olivier Clément; H Siitari; Philippe Gambert; Guy Frija; Andrew Todd-Pokropek
Confocal analysis of phosphatidylserine externalization with the use of biotinylated annexin V revealed with streptavidin-FITC, -europium, -phycoerythrin or -Texas Red in oxysterol-treated apoptotic cells.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2001;23(1):47-55.
2001: Gérard Lizard; M J Démares-Poulet; P Roignot; P Gambert
In situ hybridization detection of single-copy human papillomavirus on isolated cells, using a catalyzed signal amplification system: GenPoint.
Diagnostic cytopathology 2001;24(2):112-6.
2001: C Miguet; Serge Monier; A Bettaieb; Anne Athias; G Besséde; Aline Laubriet; S Lemaire; Dominique Néel; Philippe Gambert; Gérard Lizard
Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death.
Cell death and differentiation 2001;8(1):83-99.
2000: Edmond Kahn; Gérard Lizard; Frédérique Frouin; P Roignot; Y Chardonnet; R Di Paola
Factor analysis of confocal image sequences of human papillomavirus DNA revealed with fast red in cervical tissue sections stained with TOTO-iodide.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2000;22(2):168-74.
2000: Gérard Lizard; C Miguet; G Besséde; Serge Monier; S Gueldry; D Neel; Philippe Gambert
Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis.
Free radical biology & medicine 2000;28(5):743-53.
1999: Valérie Deckert; Gérard Lizard; Nicolas Duverger; Anne Athias; Viviane Palleau; Florence Emmanuel; M Moisant; Philippe Gambert; C Lallemant; Laurent Lagrost
Impairment of endothelium-dependent arterial relaxation by high-fat feeding in ApoE-deficient mice: toward normalization by human ApoA-I expression.
Circulation 1999;100(11):1230-5.
1999: Gérard Lizard; Serge Monier; C Cordelet; L Gesquière; Valérie Deckert; S Gueldry; Laurent Lagrost; Philippe Gambert
Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1190-200.
1999: Catherine Desrumaux; Valérie Deckert; Anne Athias; David Masson; Gérard Lizard; Viviane Palleau; Philippe Gambert; Laurent Lagrost
Plasma phospholipid transfer protein prevents vascular endothelium dysfunction by delivering alpha-tocopherol to endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):883-92.
1999: Edmond Kahn; Gérard Lizard; M Pélégrini; Frédérique Frouin; P Roignot; Y Chardonnet; R Di Paola
Four-dimensional factor analysis of confocal image sequences (4D-FAMIS) to detect and characterize low copy numbers of human papillomavirus DNA by FISH in HeLa and SiHa cells.
Journal of microscopy 1999;193(Pt 3):227-43.
1998: S Lemaire; Gérard Lizard; Serge Monier; C Miguet; S Gueldry; F Volot; Philippe Gambert; Dominique Néel
Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol.
FEBS letters 1998;440(3):434-9.
1998: Gérard Lizard; S Gueldry; Olivier Sordet; Serge Monier; Anne Athias; C Miguet; G Bessede; S Lemaire; Eric Solary; Philippe Gambert
Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(15):1651-63.
1998: Gérard Lizard; P Roignot; P Brunet-Lecomte; Y Chardonnet
Morphological analysis of in situ hybridization signals in cervical intraepithelial neoplasia containing human papillomavirus type 16 or 18: relationship with histological grade and DNA content.
Cytometry 1998;34(4):180-6.
1998: Valérie Deckert; Annie Brunet; frederique LANTOINE-ADAM; Gérard Lizard; Elisabeth Millanvoye-Van Brussel; Serge Monier; Laurent Lagrost; Monique David-Dufilho; Philippe Gambert; Marie-Aude Devynck
Inhibition by cholesterol oxides of NO release from human vascular endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(7):1054-60.
1998: Gérard Lizard; MC Chignol; Catherine Souchier; P Roignot; Y Chardonnet; D Schmitt
Detection of low copy numbers of HPV DNA by fluorescent in situ hybridization combined with confocal microscopy as an alternative to in situ polymerase chain reaction.
Journal of virological methods 1998;72(1):15-25.
1997: Gérard Lizard; S Lemaire; Serge Monier; S Gueldry; Dominique Néel; Philippe Gambert
Induction of apoptosis and of interleukin-1beta secretion by 7beta-hydroxycholesterol and 7-ketocholesterol: partial inhibition by Bcl-2 overexpression.
FEBS letters 1997;419(2-3):276-80.
1997: Gérard Lizard; M Moisant; C Cordelet; Serge Monier; Philippe Gambert; Laurent Lagrost
Induction of similar features of apoptosis in human and bovine vascular endothelial cells treated by 7-ketocholesterol.
The Journal of pathology 1997;183(3):330-8.
1997: Sarab Lizard-Nacol; Jean-Marc Riedinger; Gérard Lizard; A L Glasser; N Coudray; Gilles Chaplain; J Guerrin
Loss of heterozygosity at the TP53 gene: independent occurrence from genetic instability events in node-negative breast cancer.
International journal of cancer. Journal international du cancer 1997;72(4):599-603.
1997: Edmond Kahn; Gérard Lizard; Frédérique Frouin; P Roignot; Y Chardonnet; R Di Paola
Laser scanning confocal microscopy and factor analysis of biomedical image sequences (FAMIS) to detect and characterise HPV DNA sequences by FISH in HeLa cells.
Cytometry 1997;28(4):269-79.
1997: Gérard Lizard; MC Chignol; P Roignot; Catherine Souchier; Y Chardonnet; D Schmitt
Detection of human papillomavirus DNA in genital lesions by enzymatic in situ hybridization with Fast Red and laser scanning confocal microscopy.
The Histochemical journal 1997;29(7):545-54.
1997: Gérard Lizard; S Gueldry; Valérie Deckert; Philippe Gambert; Laurent Lagrost
Evaluation of the cytotoxic effects of some oxysterols and of cholesterol on endothelial cell growth: methodological aspects.
Pathologie-biologie 1997;45(4):281-90.
1997: Gérard Lizard; C Miguet; S Gueldry; Serge Monier; Philippe Gambert
[Flow cytometry measurement of DNA fragmentation in the course of cell death via apoptosis. New techniques for evaluation of DNA status for the pathologist].
Annales de pathologie 1997;17(1):61-6.
1997: Valérie Deckert; Laurence Perségol; L Viens; Gérard Lizard; Anne Athias; C Lallemant; Philippe Gambert; Laurent Lagrost
Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation.
Circulation 1997;95(3):723-31.
1997: A V Marionnet; Gérard Lizard; Y Chardonnet; D Schmitt
Comparative evaluation of the antiproliferative effect of cyclosporin A and gamma-interferon on normal and HPV-transformed keratinocytes by cell counting, MTT assay and tritiated thymidine incorporation.
Cell biology and toxicology 1997;13(2):115-23.
1997: F Morlevat; P Roignot; Sarab Lizard-Nacol; P Brunet-Lecomte; Gérard Lizard
[Quantification of protein p53 expression by image analysis in 58 cases of colon carcinoma. Study of correlations between sex, age, histology, Dukes stage, DNA content and lymph node invasion].
Archives d'anatomie et de cytologie pathologiques 1997;45(1):13-21.
1996: L Viens; Anne Athias; Gérard Lizard; G Simard; S Gueldry; Sylvie Braschi; Philippe Gambert; C Lallemant; Laurent Lagrost
Effect of lipid transfer activity and lipolysis on low density lipoprotein (LDL) oxidizability: evidence for lipolysis-generated non-esterified fatty acids as inhibitors of LDL oxidation.
Journal of lipid research 1996;37(10):2179-92.
1996: Gérard Lizard; Valérie Deckert; L Dubrez; M Moisant; Philippe Gambert; Laurent Lagrost
Induction of apoptosis in endothelial cells treated with cholesterol oxides.
The American journal of pathology 1996;148(5):1625-38.
1996: A V Marionnet; Gérard Lizard; MC Chignol; Y Chardonnet; D Schmitt
Differences in reactivity to cyclosporin A and interferon-gamma of normal and HPV-transformed keratinocytes.
Anticancer research 1996;16(1):257-67.
1996: Gérard Lizard; MC Chignol; Y Chardonnet; D Schmitt
Differences of reactivity to interferon gamma in HeLa and CaSki cells: a combined immunocytochemical and flow-cytometric study.
Journal of cancer research and clinical oncology 1996;122(4):223-30.
1995: Gérard Lizard; Sylvie Fournel; Laurent Genestier; N Dhedin; C Chaput; Monique Flacher; M Mutin; G Panaye; Jean-Pierre Revillard
Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis.
Cytometry 1995;21(3):275-83.
1995: Sylvie Fournel; Laurent Genestier; J P Rouault; Gérard Lizard; Monique Flacher; O Assossou; Jean-Pierre Revillard
Apoptosis without decrease of cell DNA content.
FEBS letters 1995;367(2):188-92.
1995: Gérard Lizard; Marc Maynadié; P Roignot; Sarab Lizard-Nacol; M F Poupon
Evaluation of multidrug resistant phenotype by flow cytometry with monoclonal antibodies and functional tests.
Bulletin du cancer 1995;82(3):211-7.
1995: Y Chardonnet; Gérard Lizard; MC Chignol; D Schmitt
Analytical methods for evaluation on whole cells of human papillomavirus infection.
Bulletin du cancer 1995;82(2):107-13.
1995: Gérard Lizard; P Roignot; Marc Maynadie; Sarab Lizard-Nacol; M F Poupon; M Bordes
Flow cytometry evaluation of the multidrug-resistant phenotype with functional tests involving uptake of daunorubicin, Hoechst 33342, or rhodamine 123: a comparative study.
Cancer detection and prevention 1995;19(6):527-34.
1995: B Munsch; Gérard Lizard; S Gueldry; Philippe Gambert
[Agents inducing cell death of the vascular wall].
Annales de biologie clinique 1995;53(9):473-80.
1994: Gérard Lizard; MC Chignol; Y Chardonnet; D Schmitt
Active cell membrane mechanisms involved in the exclusion of Rh 123 allow distinction between normal and tumoral cells.
Cell biology and toxicology 1994;10(5-6):399-406.
1994: Marc Maynadie; Gérard Lizard; Eric Solary; P Roignot; Paule-Marie Carli
Multidrug resistance phenotype evaluation by immunofluorescence and functional tests: comparison of two monoclonal antibodies and three fluorescent dyes in three cells lines.
Anticancer research 1994;14(6B):2605-9.
1994: Gérard Lizard; Y Usson; MC Chignol; Y Chardonnet
Improvements in visualisation and localisation of human papillomavirus DNA in CaSki cells by fluorescence in situ hybridization, laser scanning confocal microscopy and three-dimensional image reconstruction.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1994;7(1):53-61.
1994: Y Chardonnet; F Dijoud; Gérard Lizard; MC Chignol; C Soler; D Schmitt
[Detection of human papillomavirus DNA by in situ hybridization and gene amplification].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1994;317(7):659-68.
1994: Marc Maynadié; Gérard Lizard; Eric Solary; C Parmeland; Paule-Marie Carli
[Value of rhodamine 123 in the detection of minor amounts of multidrug resistant cells].
Bulletin du cancer 1994;81(5):409-13.
1994: Laurent Genestier; M T Dearden-Badet; Nathalie Bonnefoy-Berard; Gérard Lizard; Jean-Pierre Revillard
Cyclosporin A and FK506 inhibit activation-induced cell death in the murine WEHI-231 B cell line.
Cellular immunology 1994;155(2):283-91.
1994: Gérard Lizard; MC Chignol; Catherine Souchier; Daniel Schmitt; Y Chardonnet
Laser scanning confocal microscopy and quantitative microscopy with a charge coupled device camera improve detection of human papillomavirus DNA revealed by fluorescence in situ hybridization.
Histochemistry 1994;101(4):303-10.
1994: N Bonnefoy-Bérard; Laurent Genestier; Monique Flacher; J P Rouault; Gérard Lizard; M Mutin; Jean-Pierre Revillard
Apoptosis induced by polyclonal antilymphocyte globulins in human B-cell lines.
Blood 1994;83(4):1051-9.
1994: Tony Petrella; P Rat; Gérard Lizard; L Dusserre-Guion; G Poulard; R Michiels
[Papillary and cystic tumor of the pancreas. Histological, immunohistochemical and flow cytometric study].
Gastroentérologie clinique et biologique 1994;18(11):1021-7.
1993: S Oudard; Gérard Lizard; P Roignot; M F Poupon
[Cancers of the kidney: multiple drug resistance].
Bulletin du cancer 1993;80(10):866-75.
1993: Sylvie Fournel; P Morel; Jean-Pierre Revillard; Gérard Lizard; Nathalie Bonnefoy-Berard
Inhibition of human T cell response to staphylococcal enterotoxin B by prior ligation of surface CD4 molecules.
Cellular immunology 1993;150(1):194-204.
1993: Gérard Lizard; MC Chignol; Y Chardonnet; Catherine Souchier; M Bordes; Daniel Schmitt; J P Revillard
Detection of human papillomavirus DNA in CaSki and HeLa cells by fluorescent in situ hybridization. Analysis by flow cytometry and confocal laser scanning microscopy.
Journal of immunological methods 1993;157(1-2):31-8.
1993: Gérard Lizard; L Dusserre-Guion; P Proignot; J C Tremeaux; F Bejui-Thivolet
[Value of cytological study by flow cytometry or analysis of image as a complement to macroscopic study by cytoscopy. Apropos of therapeutic follow-up of a case of tumor of the bladder].
Archives d'anatomie et de cytologie pathologiques 1993;41(1):38-44.
1992: Sarab Lizard-Nacol; C Volk; Gérard Lizard; C Turc-Carel
Abnormal expression of neurofilament proteins in Ewing's sarcoma cell cultures.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1992;13(1-2):36-43.
1992: Gérard Lizard; P Roignot; L Dusserre-Guion; F Morlevat; D Michiels-Marzais; N Ferry; J C Trémeaux
Characterization of seven kidney tumors by flow cytometry: analysis of cell cycle, DNA content and P-glycoprotein expression.
European urology 1992;21 Suppl 1():39-42.
1991: Gérard Lizard; Y Chardonnet; MC Chignol; J Thivolet
Cell fusion of human and mouse cells as a source for new cells retaining human markers. Analysis of DNA content, membrane and cytoplasmic antigen expression.
Virchows Archiv. B, Cell pathology including molecular pathology 1991;60(5):301-6.
1990: Gérard Lizard; Y Chardonnet; MC Chignol; J Thivolet
Evaluation of mitochondrial content and activity with nonyl-acridine orange and rhodamine 123: flow cytometric analysis and comparison with quantitative morphometry. Comparative analysis by flow cytometry and quantitative morphometry of mitochondrial content and activity.
Cytotechnology 1990;3(2):179-88.
1989: Sarab Lizard-Nacol; Gérard Lizard; E Justrabo; C Turc-Carel
Immunologic characterization of Ewing's sarcoma using mesenchymal and neural markers.
The American journal of pathology 1989;135(5):847-55.
1989: Gérard Lizard; Y Chardonnet; MC Chignol; Daniel Schmitt; M Lenne; J Thivolet
Ultrastructural characteristics of hybrids derived from normal and hand wart keratinocytes after serial passages.
Cell biology international reports 1989;13(8):711-8.