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Laetitia Devy

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TOP 3
Laetitia Devy; Daniel T Dransfield
New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies.
Laetitia Devy; Lili Huang; Laurent Naa; Niranjan Yanamandra; Henk Pieters; Nicolas Frans; Edward Chang; Qingfeng Tao; Marc Vanhove; Annabelle Lejeune; Reinoud van Gool; Daniel J Sexton; Guannan Kuang; Douglas Rank; Shannon Hogan; Csaba Pazmany; Yu Lu Ma; Sonia Schoonbroodt; Andrew E Nixon; Robert C Ladner; Rene Hoet; Paula Henderikx; Chris Tenhoor; Shafaat A Rabbani; Maria Luisa Valentino; Clive R Wood; Daniel T Dransfield
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
Laetitia Devy; Shafaat A Rabbani; Mark Stochl; Mary Ruskowski; Ian Mackie; Laurent Naa; Mark Toews; Reinoud Van Gool; Jie Chen; Art Ley; Robert C Ladner; Daniel T Dransfield; Paula Maria Henderikx
PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor.

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All Publications

2011: Laetitia Devy; Daniel T Dransfield
New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies.
Biochemistry research international 2011;2011():191670.
2009: Laetitia Devy; Lili Huang; Laurent Naa; Niranjan Yanamandra; Henk Pieters; Nicolas Frans; Edward Chang; Qingfeng Tao; Marc Vanhove; Annabelle Lejeune; Reinoud van Gool; Daniel J Sexton; Guannan Kuang; Douglas Rank; Shannon Hogan; Csaba Pazmany; Yu Lu Ma; Sonia Schoonbroodt; Andrew E Nixon; Robert C Ladner; Rene Hoet; Paula Henderikx; Chris Tenhoor; Shafaat A Rabbani; Maria Luisa Valentino; Clive R Wood; Daniel T Dransfield
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
Cancer research 2009;69(4):1517-26.
2007: Laetitia Devy; Shafaat A Rabbani; Mark Stochl; Mary Ruskowski; Ian Mackie; Laurent Naa; Mark Toews; Reinoud Van Gool; Jie Chen; Art Ley; Robert C Ladner; Daniel T Dransfield; Paula Maria Henderikx
PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor.
Neoplasia (New York, N.Y.) 2007;9(11):927-37.
2005: Xuri Li; Marc Tjwa; Lieve Moons; Pierre Fons; Agnès Noel; Annelii Ny; Jian Min Zhou; Johan Lennartsson; Hong Li; Aernout Luttun; Annica Pontén; Laetitia Devy; Ann Bouché; Hideyasu Oh; Ann Manderveld; Silvia Blacher; David Communi; Pierre Savi; Françoise Bono; Mieke Dewerchin; Jean-Michel Foidart; Monica Autiero; Jean-Marc Herbert; Désiré Collen; Carl-Henrik Heldin; Ulf Eriksson; Peter Carmeliet
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.
The Journal of clinical investigation 2005;115(1):118-27.
2004: Els Van Valckenborgh; Peter I Croucher; Hendrik De Raeve; Chris Carron; Evy De Leenheer; Silvia Blacher; Laetitia Devy; Agnès Noël; Elke De Bruyne; Kewal Asosingh; Ivan Van Riet; Ben Van Camp; Karin Vanderkerken
Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model.
The American journal of pathology 2004;165(3):869-78.
2004: Erik Maquoi; Nor Eddine SOUNNI; Laetitia Devy; Fabrice Olivier; Francis Frankenne; Hans-Willi Krell; Frank Grams; Jean-Michel Foidart; Agnès Noël
Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4038-47.
2004: Laetitia Devy; Franciscus M H de Groot; Silvia Blacher; Amin Hajitou; Patrick H Beusker; Hans W Scheeren; Jean-Michel Foidart; Agnès Noël
Plasmin-activated doxorubicin prodrugs containing a spacer reduce tumor growth and angiogenesis without systemic toxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(3):565-7.
2003: Jean-Marie Rakic; Vincent Lambert; Laetitia Devy; Aernout Luttun; Peter Carmeliet; Carel Claes; Laurent Nguyen; Jean-Michel Foidart; Agnès Noël; Carine Munaut
Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization.
Investigative ophthalmology & visual science 2003;44(7):3186-93.
2003: Jean-Marie Rakic; Catherine Maillard; Maud Jost; Khalid Bajou; Véronique Masson; Laetitia Devy; Vincent Lambert; Jean-Michel Foidart; Agnès Noël
Role of plasminogen activator-plasmin system in tumor angiogenesis.
Cellular and molecular life sciences : CMLS 2003;60(3):463-73.
2002: Amin Hajitou; Christine Grignet; Laetitia Devy; Sarah Berndt; Silvia Blacher; Christophe Deroanne; Khalid Bajou; Timothy Fong; Yawen Chiang; Jean-Michel Foidart; Agnès Noël
The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1802-4.
2002: Jeanette Wood; Karine Bonjean; Stephan Ruetz; Akeila Bellahcène; Laetitia Devy; Jean-Michel Foidart; Vincent Castronovo; Jonathan R Green
Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid.
The Journal of pharmacology and experimental therapeutics 2002;302(3):1055-61.
2002: Nor Eddine SOUNNI; Laetitia Devy; Amin Hajitou; Francis Frankenne; Carine Munaut; Christine Gilles; Christophe Deroanne; Erik W Thompson; Jean-Michel Foidart; Agnès Noel
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):555-64.
2002: Els Van Valckenborgh; Hendrik De Raeve; Laetitia Devy; Silvia Blacher; Carine Munaut; Agnès Noël; E Van Marck; Ivan Van Riet; Ben Van Camp; Karin Vanderkerken
Murine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo.
British journal of cancer 2002;86(5):796-802.
2002: Laetitia Devy; Silvia Blacher; Christine Grignet-Debrus; Khalid Bajou; Véronique Masson; Robert D Gerard; Ann Gils; Geert Carmeliet; Peter Carmeliet; Paul J Declerck; Agnès Nöel; Jean-Michel Foidart
The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):147-54.
2002: Christophe Deroanne; Karine Bonjean; Sandrine Servotte; Laetitia Devy; Alain Colige; Nathalie Clausse; Silvia Blacher; Eric Verdin; Jean-Michel Foidart; Betty Nusgens; Vincent Castronovo
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling.
Oncogene 2002;21(3):427-36.
2002: Laetitia Devy; Patrick Hollender; Carine Munaut; Alain Colige; Roselyne Garnotel; Jean-Michel Foidart; Agnès Noël; Pierre Jeannesson
Matrix and serine protease expression during leukemic cell differentiation induced by aclacinomycin and all-trans-retinoic acid.
Biochemical pharmacology 2002;63(2):179-89.
2001: Khalid Bajou; Laetitia Devy; Véronique Masson; V Albert; Francis Frankenne; Agnès Noël; Jean-Michel Foidart
[Role of plasminogen activator inhibitor type 1 in tumor angiogenesis].
Thérapie 2001;56(5):465-72.
2001: Peter Carmeliet; Lieve Moons; Aernout Luttun; V Vincenti; Veerle Compernolle; Maria De Mol; Y Wu; Françoise Bono; Laetitia Devy; Heike Beck; Dimitri Scholz; Till Acker; T DiPalma; Mieke Dewerchin; Agnès Noel; Ingeborg Stalmans; A Barra; Silvia Blacher; Thierry VandenDriessche; A Ponten; Ulf Eriksson; Karl H Plate; Jean-Michel Foidart; Wolfgang Schaper; D S Charnock-Jones; Daniel J Hicklin; Jean-Marc Herbert; Désiré Collen; M Graziella Persico
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Nature medicine 2001;7(5):575-83.
2001: Amin Hajitou; Nor Eddine SOUNNI; Laetitia Devy; Christine Grignet-Debrus; Jean-Marc Lewalle; H Li; Christophe Deroanne; H Lu; Alain Colige; Betty Nusgens; Francis Frankenne; Anne Maron; Patrice Yeh; Michel Perricaudet; Y Chang; Claudine Soria; CM Calberg-Bacq; Jean-Michel Foidart; Agnès Noël
Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis.
Cancer research 2001;61(8):3450-7.
2001: Agnès Noel; V Albert; Khalid Bajou; Christèle Bisson; Laetitia Devy; Francis Frankenne; Erik Maquoi; Véronique Masson; Nor Eddine SOUNNI; Jean-Michel Foidart
New functions of stromal proteases and their inhibitors in tumor progression.
Surgical oncology clinics of North America 2001;10(2):417-32, x-xi.
2001: Silvia Blacher; Laetitia Devy; Mike Burbridge; G Roland; G Tucker; Agnès Noël; J M Foidart
Improved quantification of angiogenesis in the rat aortic ring assay.
Angiogenesis 2001;4(2):133-42.
1998: Florence Kebers; Jean-Marc Lewalle; Jean F Desreux; Carine Munaut; Laetitia Devy; Jean-Michel Foidart; Agnès Noël
Induction of endothelial cell apoptosis by solid tumor cells.
Experimental cell research 1998;240(2):197-205.
1997: Laetitia Devy; Agnès Noël; Eugenia N Baramova; Khalid Bajou; Chantal Trentesaux; JC Jardillier; Jean-Michel Foidart; Pierre Jeannesson
Production and activation of matrix metalloprotease-9 (MMP-9) by HL-60 promyelocytic leukemia cells.
Biochemical and biophysical research communications 1997;238(3):842-6.
1997: Pierre Jeannesson; R Lahlil; Benoît Chénais; Laetitia Devy; Reynald Gillet; A Aries; Franck Morceau; Chantal Trentesaux
Anthracyclines as tumor cell differentiating agents: effects on the regulation of erythroid gene expression.
Leukemia & lymphoma 1997;26(5-6):575-87.
1997: N Rafki; Françoise Liautaud-Roger; Laetitia Devy; Chantal Trentesaux; Jean Dufer
P53 protein expression in human multidrug-resistant CEM lymphoblasts.
Leukemia research 1997;21(2):147-52.
1997: Agnès Noël; Christine Gilles; Khalid Bajou; Laetitia Devy; Florence Kebers; Jean-Marc Lewalle; Erik Maquoi; Carine Munaut; Albert G Remacle; Jean-Michel Foidart
Emerging roles for proteinases in cancer.
Invasion & metastasis 1997;17(5):221-39.
1996: F Morceau; A Aries; R Lahlil; Laetitia Devy; J C Jardillier; Pierre Jeannesson; Chantal Trentesaux
Evidence for distinct regulation processes in the aclacinomycin- and doxorubicin-mediated differentiation of human erythroleukemic cells.
Biochemical pharmacology 1996;51(6):839-45.