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Umeo Ito

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Umeo Ito; Yoji Hakamata; Emiko Kawakami; Kiyomitsu Oyanagi
Temporary [corrected] cerebral ischemia results in swollen astrocytic end-feet that compress microvessels and lead to delayed [corrected] focal cortical infarction.
Umeo Ito; Yoji Hakamata; Emiko Kawakami; Kiyomitsu Oyanagi
Degeneration of astrocytic processes and their mitochondria in cerebral cortical regions peripheral to the cortical infarction: heterogeneity of their disintegration is closely associated with disseminated selective neuronal necrosis and maturation of injury.
Umeo Ito; Jun Nagasao; Emiko Kawakami; Kiyomitsu Oyanagi
Fate of disseminated dead neurons in the cortical ischemic penumbra: ultrastructure indicating a novel scavenger mechanism of microglia and astrocytes.

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All Publications

2011: Umeo Ito; Yoji Hakamata; Emiko Kawakami; Kiyomitsu Oyanagi
Temporary [corrected] cerebral ischemia results in swollen astrocytic end-feet that compress microvessels and lead to delayed [corrected] focal cortical infarction.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(1):328-38.
2009: Umeo Ito; Yoji Hakamata; Emiko Kawakami; Kiyomitsu Oyanagi
Degeneration of astrocytic processes and their mitochondria in cerebral cortical regions peripheral to the cortical infarction: heterogeneity of their disintegration is closely associated with disseminated selective neuronal necrosis and maturation of injury.
Stroke; a journal of cerebral circulation 2009;40(6):2173-81.
2007: Umeo Ito; Jun Nagasao; Emiko Kawakami; Kiyomitsu Oyanagi
Fate of disseminated dead neurons in the cortical ischemic penumbra: ultrastructure indicating a novel scavenger mechanism of microglia and astrocytes.
Stroke; a journal of cerebral circulation 2007;38(9):2577-83.
2006: Umeo Ito; Toshihiko Kuroiwa; Jun Nagasao; Emiko Kawakami; Kiyomitsu Oyanagi
Temporal profiles of axon terminals, synapses and spines in the ischemic penumbra of the cerebral cortex: ultrastructure of neuronal remodeling.
Stroke; a journal of cerebral circulation 2006;37(8):2134-9.
2006: Umeo Ito; Emiko Kawakami; Jun Nagasao; Toshihiko Kuroiwa; Imaharu Nakano; Kiyomitsu Oyanagi
Restitution of ischemic injuries in penumbra of cerebral cortex after temporary ischemia.
Acta neurochirurgica. Supplement 2006;96():239-43.
2003: Umeo Ito; Toshihiko Kuroiwa; S Hanyu; Y Hakamata; Emiko Kawakami; Imaharu Nakano; Kiyomitsu Oyanagi
Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction--ultrastructure, gravimetry and Evans' blue extravasation.
Acta neurochirurgica. Supplement 2003;86():131-5.
2001: Dirk M Hermann; T Kuroiwa; R Hata; F Gillardon; Umeo Ito; Günter Mies
Expression of redox factor-1, p53-activated gene 608 and caspase-3 messenger RNAs following repeated unilateral common carotid artery occlusion in gerbils--relationship to delayed cell injury and secondary failure of energy state.
Neuroscience 2001;102(4):779-87.
2000: Toshihiko Kuroiwa; Günter Mies; D Hermann; Y Hakamata; S Hanyu; Umeo Ito
Regional differences in the rate of energy impairment after threshold level ischemia for induction of cerebral infarction in gerbils.
Acta neuropathologica 2000;100(6):587-94.
2000: Toshihiko Kuroiwa; Ichiro Yamada; S Endo; Y Hakamata; Umeo Ito
3-Nitropropionic acid preconditioning ameliorates delayed neurological deterioration and infarction after transient focal cerebral ischemia in gerbils.
Neuroscience letters 2000;283(2):145-8.
2000: Toshihiko Kuroiwa; Umeo Ito; Y Hakamata; S Hanyu; Günter Mies; D Hermann
Evolution of energy failure after repeated cerebral ischemia in gerbils.
Acta neurochirurgica. Supplement 2000;76():43-6.
2000: Y Hakamata; Umeo Ito; Toshihiko Kuroiwa; S Hanyu; N Ohashi; Imaharu Nakano
Combined therapy utilizing a novel Na+/H+ exchange inhibitor (SM-20220) and THAM for ischemic brain edema.
Acta neurochirurgica. Supplement 2000;76():165-9.
1999: Katsuya Yamamoto; Hiroyuki Hamaguchi; Kaoru Nagata; M Hara; O Tone; H Tomita; Umeo Ito
Isolated recurrence of granulocytic sarcoma of the brain: successful treatment with surgical resection, intrathecal injection, irradiation and prophylactic systemic chemotherapy.
Japanese journal of clinical oncology 1999;29(4):214-8.
1998: Kuniaki Tsuchiya; K Ishikawa; Sadakiyo Watabiki; O Tone; Kazuhiro Taki; Chie Haga; M Takashima; Umeo Ito; R Okeda; Hidehiro Mizusawa; K Ikeda
A clinical, genetic, neuropathological study in a Japanese family with SCA 6 and a review of Japanese autopsy cases of autosomal dominant cortical cerebellar atrophy.
Journal of the neurological sciences 1998;160(1):54-9.
1998: Dirk M Hermann; T Kuroiwa; Umeo Ito; Günter Mies
Expression of c-jun, hsp72 and gfap following repeated unilateral common carotid artery occlusion in gerbils-correlates of delayed ischemic injury.
Brain research 1998;799(1):35-43.
1998: Yasunari Niimi; Umeo Ito; O Tone; K Yoshida; S Sato; Alejandro Berenstein
Multiple spinal perimedullary arteriovenous fistulae associated with the parkes-weber syndrome. A case report.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 1998;4(2):151-7.
1998: T Shimizu; D Shiro; K Yonekura; H Ikenouchi; K Harada; T Takahashi; A Takenaka; M Komina; Umeo Ito
[Calcified aneurysm of sinus of Valsalva in the aged].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1998;87(5):925-7.
1997: H Tomita; O Tone; Umeo Ito
Hemispheric cerebral atrophy after traumatic extra-axial hematoma in adults.
Neurologia medico-chirurgica 1997;37(11):819-24.
1997: S Hanyu; Umeo Ito; Y Hakamata; Imaharu Nakano
Topographical analysis of cortical neuronal loss associated with disseminated selective neuronal necrosis and infarction after repeated ischemia.
Brain research 1997;767(1):154-7.
1997: Umeo Ito; S Hanyu; Y Hakamata; M Nakamura; K Arima
Ultrastructure of astrocytes associated with selective neuronal death of cerebral cortex after repeated ischemia.
Acta neurochirurgica. Supplement 1997;70():46-9.
1997: Y Hakamata; S Hanyu; Toshihiko Kuroiwa; Umeo Ito
Brain edema associated with progressive selective neuronal death or impending infarction in the cerebral cortex.
Acta neurochirurgica. Supplement 1997;70():20-2.
1996: O Tone; Umeo Ito; H Tomita; H Akimoto; H Sakemi
Correlation between cerebral blood flow values obtained by Xenon/CT and Kety-Schmidt (N2O) methods.
Acta neurologica Scandinavica. Supplementum 1996;166():18-21.
1995: Y Hakamata; Umeo Ito; S Hanyu; M Yoshida
Long-term high-colloid oncotic therapy for ischemic brain edema in gerbils.
Stroke; a journal of cerebral circulation 1995;26(11):2149-53.
1995: S Hanyu; Umeo Ito; Y Hakamata; M Yoshida
Transition from ischemic neuronal necrosis to infarction in repeated ischemia.
Brain research 1995;686(1):44-8.
1995: Umeo Ito
[Pathophysiology of brain edema--general remarks].
Nō to shinkei = Brain and nerve 1995;47(3):219-37.
1994: H Tomita; Umeo Ito; O Tone; H Masaoka; B Tominaga
Atrophy and maldevelopment of the ipsilateral cerebral hemisphere after acute subdural hematoma in infants.
Surgical neurology 1994;42(6):498-504.
1994: Zbigniew Czernicki; H Tomita; Umeo Ito; Jerzy Jurkiewicz; G Stepińska; J Walecki
[Application of transcranial Doppler ultrasonography in the assessment of cerebrovascular reactivity studies and cerebral vascular reserve estimation in patients with focal brain injury].
Neurologia i neurochirurgia polska 1994;28(3):351-61.
1994: O Tone; Umeo Ito; H Tomita; H Masaoka; B Tominaga
High colloid oncotic therapy for brain edema with cerebral hemorrhage.
Acta neurochirurgica. Supplementum 1994;60():568-70.
1994: H Tomita; Umeo Ito; Kikuo Ohno; K Hirakawa
Chronological changes in brain edema induced by experimental intracerebral hematoma in cats.
Acta neurochirurgica. Supplementum 1994;60():558-60.
1994: H Tomita; Umeo Ito; O Tone; H Masaoka; B Tominaga
High colloid oncotic therapy for contusional brain edema.
Acta neurochirurgica. Supplementum 1994;60():547-9.
1994: Umeo Ito; H Tomita; O Tone; H Masaoka; B Tominaga
Peritumoral edema in meningioma: a contrast enhanced CT study.
Acta neurochirurgica. Supplementum 1994;60():361-4.
1994: Zbigniew Czernicki; T Kuroiwa; K Ohno; S Endo; Umeo Ito
Effect of acetazolamide on early ischemic cerebral edema in gerbils.
Acta neurochirurgica. Supplementum 1994;60():329-31.
1993: Y Hakamata; Umeo Ito; S Hanyu; M Yoshida
Changes in cranial and rectal temperature, blood pressure and arterial blood gas during and after unilateral and bilateral forebrain ischemia in Mongolian gerbils.
Neuroscience research 1993;18(1):73-8.
1993: O Tone; Umeo Ito; H Tomita; H Masaoka; B Tominaga
[Measurement of serum colloid oncotic pressure as a parameter of hemodilution and hemoconcentration in hypervolemic-hyperdynamic therapy for symptomatic vasospasm].
No shinkei geka. Neurological surgery 1993;21(5):437-41.
1993: S Hanyu; Umeo Ito; Y Hakamata; M Yoshida
Repeated unilateral carotid occlusion in Mongolian gerbils: quantitative analysis of cortical neuronal loss.
Acta neuropathologica 1993;86(1):16-20.
1991: Umeo Ito; T Sakamoto; Y Hada
[Clinical features of main and peripheral pulmonary artery stenosis: significance of auscultation and phonocardiography].
Journal of cardiology 1991;21(4):963-81.
1990: H Tomita; Umeo Ito; J Saito; T Maehara
Cerebral atrophy after severe head injury.
Advances in neurology 1990;52():553.
1990: Umeo Ito; H J Reulen; H Tomita; J Ikeda; J Saito; T Maehara
A computed tomography study on formation, propagation, and resolution of edema fluid in metastatic brain tumors.
Advances in neurology 1990;52():459-68.
1990: Hans-Jürgen Reulen; P Huber; Umeo Ito; U Gröger
Peritumoral brain edema. A keynote address.
Advances in neurology 1990;52():307-15.
1990: Umeo Ito; H Tomita; O Tone; T Shishido; H Hayashi
Formation and resolution of white matter oedema in various types of brain tumours.
Acta neurochirurgica. Supplementum 1990;51():149-51.
1988: Umeo Ito; H J Reulen; H Tomita; J Ikeda; J Saito; T Maehara
Formation and propagation of brain oedema fluid around human brain metastases. A CT Study.
Acta neurochirurgica 1988;90(1-2):35-41.
1988: Hans-Jürgen Reulen; S Graber; P Huber; Umeo Ito
Factors affecting the extension of peritumoural brain oedema. A CT-study.
Acta neurochirurgica 1988;95(1-2):19-24.
1987: S Yamazaki; Umeo Ito; H Tomita; Y Takada; Y Inaba; R Okeda
[Melanosis of choroid plexus papilloma of the lateral ventricle: a case report].
No shinkei geka. Neurological surgery 1987;15(9):1033-7.
1987: M Seida; Umeo Ito; S Tomida; S Yamazaki; Y Inaba
[Ventriculo-peritoneal shunt malfunction with anti-siphon device in normal-pressure hydrocephalus. Report of three cases].
Neurologia medico-chirurgica 1987;27(8):769-73.
1986: K Kito; Umeo Ito; H Tomita; S Tsuruoka; Y Inaba
[Outcome prediction by recovering signs in acute head injury].
Neurologia medico-chirurgica 1986;26(10):801-6.
1986: Umeo Ito; H Tomita; K Kito; Y Ueki; Y Inaba
CT enhancement after prolonged high-dose contrast infusion in the early stage of cerebral infarction.
Stroke; a journal of cerebral circulation 1986;17(3):424-30.
1986: M Seida; Umeo Ito; K Kito; S Tomida; Y Inaba
[Traumatic cerebellar hematoma in children. Report of two cases].
Neurologia medico-chirurgica 1986;26(4):318-22.
1986: M Tsuyumu; H Hiratsuka; Y Inaba; Umeo Ito; H J Reulen
[A mechanism of development and resolution of vasogenic brain edema].
No shinkei geka. Neurological surgery 1986;14(3 Suppl):287-94.
1986: F Igarashi; Umeo Ito; H Inagaki; M Oazama; R Kurachi
[Public health nurses under the National Health Insurance system: at the conclusion of their historical mission].
[Hokenfu zasshi] The Japanese journal for public health nurse 1986;42(3):242-58.
1986: K Kito; Umeo Ito; K Okada; H Tomita; Y Inaba
[Measuring subtemporal subdural intracranial pressure using a catheter-tip pressure transducer].
Neurologia medico-chirurgica 1986;26(2):147-52.
1986: Umeo Ito; H Tomita; S Yamazaki; Y Takada; Y Inaba
Brain swelling and brain oedema in acute head injury.
Acta neurochirurgica 1986;79(2-4):120-4.
1986: Umeo Ito; H Tomita; S Yamazaki; Y Takada; Y Inaba
CT findings of leptomeningeal and periventricular dissemination of tumors. Report of four cases.
Clinical neurology and neurosurgery 1986;88(2):115-20.
1986: S Tomida; Y Matsushima; Umeo Ito; S Yamazaki; Y Inaba
[Five year observation of two children of moyamoya disease after encephalo-duro-arterio-synangiosis (EDAS) operation].
No to hattatsu. Brain and development 1986;18(1):55-61.
1986: Umeo Ito; H Tomita; S Yamazaki; Y Takada; Y Inaba
Enhanced cisternal drainage and cerebral vasospasm in early aneurysm surgery.
Acta neurochirurgica 1986;80(1-2):18-23.
1986: Umeo Ito; H J Reulen; P Huber
Spatial and quantitative distribution of human peritumoural brain oedema in computerized tomography.
Acta neurochirurgica 1986;81(1-2):53-60.
1985: Umeo Ito; H Tomita; M Matsuura; S Yamazaki; Y Takada; Y Inaba
Computer-analyzed EEG before and after bypass surgery. Quantification by a computerized wave form recognition method.
Clinical neurology and neurosurgery 1985;87(4):267-74.
1984: K Ohno; Umeo Ito; Y Inaba
Regional cerebral blood flow and stroke index after left carotid artery ligation in the conscious gerbil.
Brain research 1984;297(1):151-7.
1984: H Koyama; T Tazaki; M Yamazaki; Umeo Ito; S Ueda
[Team work for better regional public health activities. A panel discussion].
[Hokenfu zasshi] The Japanese journal for public health nurse 1984;40(3):170-91.
1982: S Ito; Umeo Ito; T Tada; T Nagasaka; M Matsushita
[Public health nursing and a volunteer organization for handicapped children].
[Hokenfu zasshi] The Japanese journal for public health nurse 1982;38(5):348-61.
1980: Umeo Ito; K Ohno; T Yamaguchi; H Takei; H Tomita; Y Inaba
Effect of hypertension on blood-brain barrier. Change after restoration of blood flow in post-ischemic gerbil brains. An electronmicroscopic study.
Stroke; a journal of cerebral circulation 1980;11(6):606-11.
1980: Umeo Ito; K Ohno; T Yamaguchi; H Tomita; Y Inaba; M Kashima
Transient appearance of "no-reflow" phenomenon in Mongolian gerbils.
Stroke; a journal of cerebral circulation 1980;11(5):517-21.
1980: Umeo Ito; K Ohno; Y Suganuma; K Suzuki; Y Inaba
Effect of steroid on ischemic brain edema. Analysis of cytotoxic and vasogenic edema occurring during ischemia and after restoration of blood flow.
Stroke; a journal of cerebral circulation 1980;11(2):166-72.
1979: Umeo Ito; K Ohno; R Nakamura; F Suganuma; Y Inaba
Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability.
Stroke; a journal of cerebral circulation 1979;10(5):542-7.
1979: Umeo Ito; Y Inaba
Cerebrospinal fluid cytology after subarachnoid hemorrhage.
Journal of neurosurgery 1979;51(3):352-4.
1979: Umeo Ito
[Further involvement with the local population in public health nursing].
[Hokenfu zasshi] The Japanese journal for public health nurse 1979;35(6):464-5.
1978: M Tsuyumu; Umeo Ito; H Hiratsuka; Y Inaba; H J Reulen
[Dynamics of resolution of vasogenic brain edema. I. Measurement of edema clearance into ventricular CSF (author's transl)].
Neurologia medico-chirurgica 1978;18(9 Pt 2):665-71.
1977: Umeo Ito
[Activities of Nakayoshi Kai, an organization of public health nurses in Aichi Pref.--a diary of a public health nurse].
[Hokenfu zasshi] The Japanese journal for public health nurse 1977;33(4):212-4.
1977: Umeo Ito
[Activities of Nakayoshi Kai, an organization of public health nurses in Aichi Pref.--friendship and unorthodox behaviors of the members].
[Hokenfu zasshi] The Japanese journal for public health nurse 1977;33(4):194-7.
1976: J J Bubis; T Fujimoto; Umeo Ito; B J Mrsulja; M Spatz; I Klatzo
Experimental cerebral ischemia in Mongolian gerbils. v. Ultrastructural changes in H3 sector of the hippocampus.
Acta neuropathologica 1976;36(3):285-94.
1976: B B Mrsulja; B J Mrsulja; M Spatz; Umeo Ito; J T Walker; I Klatzo
Experimental cerebral ischemia in Mongolian gerbils. IV. Behaviour of biogenic amines.
Acta neuropathologica 1976;36(1):1-8.
1976: Umeo Ito; K Ohno; H Tomita; Y Inaba
[Cerebral changes during recirculation following temporary ischemia in Mongolian gerbils (author's transl)].
Neurologia medico-chirurgica 1976;16(4 pt 2):313-22.
1976: Umeo Ito; K G Go; J T Walker; M Spatz; I Klatzo
Experimental cerebral ischemia in Mongolian gerbils III. Behaviour of the blood-brain barrier.
Acta neuropathologica 1976;34(1):1-6.
1975: B B Mrsulja; B J Mrsulja; Umeo Ito; J T Walker; M Spatz; I Klatzo
Experimental cerebral ischemia in Mongolian gerbils. II. Changes in carbohydrates.
Acta neuropathologica 1975;33(2):91-103.
1975: Umeo Ito; M Spatz; J T Walker; I Klatzo
Experimental cerebral ischemia in mongolian gerbils. I. Light microscopic observations.
Acta neuropathologica 1975;32(3):209-23.
1974: A Takada; Y Takada; Umeo Ito; J Minowada
Shared antigenic determinants between human brain and human T-cell line.
Clinical and experimental immunology 1974;18(4):491-8.
1974: Umeo Ito; K Hashimoto; Y Inaba
[A histochemical and electronmicroscopic study of an osteochondroma arising from the posterior clinoid process (author's transl)].
No shinkei geka. Neurological surgery 1974;2(9):601-11.
1974: Umeo Ito; K Hashimoto; Y Inaba
Osteochondroma of the posterior clinoid process. Report of a case with special reference to its histogenesis.
Acta neuropathologica 1974;27(4):329-35.
1974: J L Costa; Umeo Ito; M Spatz; I Klatzo; C Demirjian
5-Hydroxytryptamine accumulation in cerebrovascular injury.
Nature 1974;248(444):135-6.
1974: Umeo Ito; T Fujimoto; Y Inaba
[Formation of the chronic subdural hematoma: 2. A patho-anatomical study of sequel of the traumatic acute subdural hemorrhage (author's transl)].
No shinkei geka. Neurological surgery 1974;2(2):129-43.
1974: Umeo Ito; T Fujimoto; Y Inaba
[Formation of the chronic subdural hematoma: 1. Clinico-pathological study of the chronic subdural hematoma (author's transl)].
No shinkei geka. Neurological surgery 1974;2(1):47-61.
1973: K Ono; Umeo Ito; Y Fukushima; Y Inaba
[Multiple and bilateral aneurysm of the internal carotid arteries caused by osteomyelitis of the skull. Report of a case].
Rinshō shinkeigaku = Clinical neurology 1973;13(8):513-7.
1973: Umeo Ito; Y Inaba
[Cerebrospinal fluid cytology for detection of subarachnoid hemorrhage long after the attack and estimation of post-hemorrhagic duration].
Rinshō shinkeigaku = Clinical neurology 1973;13(5):283-90.
1973: K Ono; Umeo Ito; Y Fukushima; Y Inaba
Multiple mycotic aneurysms of internal carotid arteries caused by osteomyelitis of skull. Report of a case.
The Bulletin of Tokyo Medical and Dental University 1973;20(1):51-8.
1972: Umeo Ito; Y Inaba
A simple sedimentation chamber adaptable to the laboratory centrifuge.
American journal of clinical pathology 1972;58(5):590-5.
1972: T Sakamoto; S Ookubo; J Yoshikawa; K Inoue; Umeo Ito
Unusual diastolic heart beat in pericardial effusion.
Japanese heart journal 1972;13(5):379-93.
1970: Umeo Ito; H Hiratsuka; A Kamisasa; K Komatsu
[New cell-collecting device for cytodiagnosis of the cerebrospinal fluid].
Nō to shinkei = Brain and nerve 1970;22(5):537-43.
1970: Umeo Ito; Y Inaba
Electron microscopic observation of cerebro-spinal fluid cells--a new method for embedding of CSF cells.
Journal of electron microscopy 1970;19(3):265-70.
1969: Y Inaba; S Toyota; Y Matsushima; Umeo Ito; Y Fukushima
[Management of hydrocephalus: problems of ventriculo-auriculostomy or vetriculo-peritonostomy, with special reference to ventricular obstruction in the choroid plexus].
Geka chiryo. Surgical therapy 1969;20(6):613-23.
1967: T Shimamine; M Takahama; Umeo Ito; Y Adachi; S Tsunakawa
Acute radiation injury of bone marrow and the early phase of its regeneration.
Acta pathologica japonica 1967;17(3):317-9.
1965: Umeo Ito
Electron microscopic study on benzene intoxicated rat bone marrow, with special reference to its reticulo-endothelial structure.
The Bulletin of Tokyo Medical and Dental University 1965;12(1):1-29.