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Randy Brutkiewicz
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Research Profile (preview)
Chemicals & Drugs
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Network (preview)
16
Sriram, Venkataraman
12
Renukaradhya, Gourapura
11
Du, Wenjun
10
Gervay-Hague, Jacquelyn
7
Cho, Sungyoo
7
Roberts, Tonya
7
Khan, Masood
6
Lin, Yinling
6
Blum, Janice
5
Li, Ping
5
Van Kaer, Luc
4
Spence, Philip
4
Chang, Cheong-Hee
3
Bennink, Jack
3
Hayakawa, Kyoko
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Publications
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Geonetwork of Randy Brutkiewicz (preview)
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All Publications
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2009: Khan Masood A; Gallo Richard M; Renukaradhya Gourapura J; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4744-50.
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2009: Li Wei; Sofi M Hanief; Wei Datsen G; Du Wenjun; Gervay-Hague Jacquelyn; Renukaradhya Gourapura J; Brutkiewicz Randy R; Chang Cheong-Hee
MHC class II-expressing thymocytes suppress invariant NKT cell development.
Immunology and cell biology 2009;87(2):186-9.
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2008: Renukaradhya Gourapura J; Khan Masood A; Shaji Daniel; Brutkiewicz Randy R
Vesicular stomatitis virus matrix protein impairs CD1d-mediated antigen presentation through activation of the p38 MAPK pathway.
Journal of virology 2008;82(24):12535-42.
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2008: Khan Masood A; Sriram Venkataraman; Renukaradhya Gourapura J; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
Apoptosis-induced inhibition of CD1d-mediated antigen presentation: different roles for caspases and signal transduction pathways.
Immunology 2008;125(1):80-90.
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2008: Mann Brandon A; Huang Julia He; Li Ping; Chang Hua-Chen; Slee Roger B; O'Sullivan Audrey; Anita Mathur; Yeh Norman; Klemsz Michael J; Brutkiewicz Randy R; Blum Janice S; Kaplan Mark H
Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2008;28(6):367-80.
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2008: Renukaradhya Gourapura J; Khan Masood A; Vieira Marcus; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma.
Blood 2008;111(12):5637-45.
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2008: Sriram Venkataraman; Willard Claire A; Liu Jianyun; Brutkiewicz Randy R
Importance of N-linked glycosylation in the functional expression of murine CD1d1.
Immunology 2008;123(2):272-81.
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2007: Li Wei; Sofi M Hanief; Yeh Norman; Sehra Sarita; McCarthy Brian P; Patel Dipak R; Brutkiewicz Randy R; Kaplan Mark H; Chang Cheong-Hee
Thymic selection pathway regulates the effector function of CD4 T cells.
The Journal of experimental medicine 2007;204(9):2145-57.
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2007: Brutkiewicz Randy R; Willard Claire A; Gillett-Heacock Kristin K; Pawlak M Robert; Bailey Jennifer C; Khan Masood A; Nagala Manjula; Du Wenjun; Gervay-Hague Jacquelyn; Renukaradhya Gourapura J
Protein kinase C delta is a critical regulator of CD1d-mediated antigen presentation.
European journal of immunology 2007;37(9):2390-5.
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2007: Yao Yongxue; Li Ping; Singh Pratibha; Thiele Allison T; Wilkes David S; Renukaradhya Gourapura J; Brutkiewicz Randy R; Travers Jeffrey B; Luker Gary D; Hong Soon-Cheol; Blum Janice S; Chang Cheong-Hee
Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II.
Cellular immunology 2007;246(2):92-102.
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2007: Broxmeyer Hal E; Dent Alexander; Cooper Scott; Hangoc Giao; Wang Zheng-Yu; Du Wenjun; Gervay-Haque Jacquelyn; Sriram Venkataraman; Renukaradhya Gourapura J; Brutkiewicz Randy R
A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus.
Experimental hematology 2007;35(4 Suppl 1):87-93.
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2006: Webb Tonya J Roberts; Litavecz Roberta A; Khan Masood A; Du Wenjun; Gervay-Hague Jacquelyn; Renukaradhya Gourapura J; Brutkiewicz Randy R
Inhibition of CD1d1-mediated antigen presentation by the vaccinia virus B1R and H5R molecules.
European journal of immunology 2006;36(10):2595-600.
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2006: Brutkiewicz Randy R
CD1d ligands: the good, the bad, and the ugly.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):769-75.
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2006: Larkin Jonathan; Renukaradhya Gourapura J; Sriram Venkataraman; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
CD44 differentially activates mouse NK T cells and conventional T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):268-79.
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2006: Renukaradhya Gourapura J; Sriram Venkataraman; Du Wenjun; Gervay-Hague Jacquelyn; Van Kaer Luc; Brutkiewicz Randy R
Inhibition of antitumor immunity by invariant natural killer T cells in a T-cell lymphoma model in vivo.
International journal of cancer. Journal international du cancer 2006;118(12):3045-53.
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2006: Fujita Kazuhiko; Kobayashi Makiko; Brutkiewicz Randy R; Hanafusa Toshiaki; Herndon David N; Suzuki Fujio
Role for IL-4 nonproducing NKT cells in CC-chemokine ligand 2-induced Th2 cell generation.
Immunology and cell biology 2006;84(1):44-50.
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2006: Wang Zheng-Yu; Kusam Saritha; Munugalavadla Veerendra; Kapur Reuben; Brutkiewicz Randy R; Dent Alexander L
Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):880-8.
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2006: Zullo Alfred J; Brutkiewicz Randy R; Taparowsky Elizabeth J
Selective identification of Valpha14i T cells using slide-immobilized, CD1d-antigen complexes.
Journal of immunoassay & immunochemistry 2006;27(3):207-12.
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2005: Li Ping; Wang Nan; Zhou Delu; Yee Christina S K; Chang Cheong-Hee; Brutkiewicz Randy R; Blum Janice S
Disruption of MHC class II-restricted antigen presentation by vaccinia virus.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6481-8.
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2005: Renukaradhya Gourapura J; Webb Tonya J Roberts; Khan Masood A; Lin Yin Ling; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4301-8.
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2005: Cho Sungyoo; Knox Kenneth S; Kohli Lisa M; He Johnny J; Exley Mark A; Wilson S Brian; Brutkiewicz Randy R
Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex.
Virology 2005;337(2):242-52.
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2005: Sriram Venkataraman; Du Wenjun; Gervay-Hague Jacquelyn; Brutkiewicz Randy R
Cell wall glycosphingolipids of Sphingomonas paucimobilis are CD1d-specific ligands for NKT cells.
European journal of immunology 2005;35(6):1692-701.
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2005: Zhou Delu; Li Ping; Lin Yinling; Lott Jeremy M; Hislop Andrew D; Canaday David H; Brutkiewicz Randy R; Blum Janice S
Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens.
Immunity 2005;22(5):571-81.
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2005: Hage Chadi A; Kohli Lisa L; Cho Sungyoo; Brutkiewicz Randy R; Twigg Homer L; Knox Kenneth S
Human immunodeficiency virus gp120 downregulates CD1d cell surface expression.
Immunology letters 2005;98(1):131-5.
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2005: Lin Yinling; Roberts Tonya J; Wang Chyung-Ru; Cho Sungyoo; Brutkiewicz Randy R
Long-term loss of canonical NKT cells following an acute virus infection.
European journal of immunology 2005;35(3):879-89.
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2005: Lin Yinling; Roberts Tonya J; Spence Philip M; Brutkiewicz Randy R
Reduction in CD1d expression on dendritic cells and macrophages by an acute virus infection.
Journal of leukocyte biology 2005;77(2):151-8.
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2004: Renukaradhya J Gourapura; Sriram Venkataraman; Polakova Katarina; Russ Gustav; Brutkiewicz Randy R
Development of a quantitative cell-based intracellular ELISA for the screening of B cell hybridoma supernatants: a novel rapid assay to detect positive clones.
Hybridoma and hybridomics 2004;23(6):373-9.
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2004: Roberts Tonya J; Lin Yinling; Spence Philip M; Van Kaer Luc; Brutkiewicz Randy R
CD1d1-dependent control of the magnitude of an acute antiviral immune response.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3454-61.
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2003: Lin Yinling; Roberts Tonya J; Sriram Venkataraman; Cho Sungyoo; Brutkiewicz Randy R
Myeloid marker expression on antiviral CD8+ T cells following an acute virus infection.
European journal of immunology 2003;33(10):2736-43.
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2003: Williams Kristi L; Zullo Alfred J; Kaplan Mark H; Brutkiewicz Randy R; Deppmann Christopher D; Vinson Charles; Taparowsky Elizabeth J
BATF transgenic mice reveal a role for activator protein-1 in NKT cell development.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2417-26.
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2003: Stanic Aleksandar K; De Silva A Dharshan; Park Jang-June; Sriram Venkataraman; Ichikawa Shinichi; Hirabyashi Yoshio; Hayakawa Kyoko; Van Kaer Luc; Brutkiewicz Randy R; Joyce Sebastian
Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1849-54.
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2003: Brutkiewicz Randy R; Lin Yinling; Cho Sungyoo; Hwang Yu Kyeong; Sriram Venkataraman; Roberts Tonya J
CD1d-mediated antigen presentation to natural killer T (NKT) cells.
Critical reviews in immunology 2003;23(5-6):403-19.
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2002: Kim Young-June; Brutkiewicz Randy R; Broxmeyer Hal E
Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells.
Blood 2002;100(9):3253-60.
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2002: Haque M Azizul; Mizobuchi Teruaki; Yasufuku Kazuhiro; Fujisawa Takehiko; Brutkiewicz Randy R; Zheng Yan; Woods Kena; Smith Gerald N; Cummings Oscar W; Heidler Kathleen M; Blum Janice S; Wilkes David S
Evidence for immune responses to a self-antigen in lung transplantation: role of type V collagen-specific T cells in the pathogenesis of lung allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1542-9.
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2002: Sriram Venkataraman; Cho Sungyoo; Li Ping; O'Donnell Patrick W; Dunn Claire; Hayakawa Kyoko; Blum Janice S; Brutkiewicz Randy R
Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8197-202.
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2002: Roberts Tonya J; Sriram Venkataraman; Spence Philip M; Gui Ming; Hayakawa Kyoko; Bacik Igor; Bennink Jack R; Yewdell Jonathan W; Brutkiewicz Randy R
Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5409-14.
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2002: Brutkiewicz Randy R; Sriram Venkataraman
Natural killer T (NKT) cells and their role in antitumor immunity.
Critical reviews in oncology/hematology 2002;41(3):287-98.
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2002: De Silva A Dharshan; Park J-June; Matsuki Naoto; Stanic Aleksandar K; Brutkiewicz Randy R; Medof M Edward; Joyce Sebastian
Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):723-33.
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2001: Hobbs J A; Cho S; Roberts T J; Sriram V; Zhang J; Xu M; Brutkiewicz R R
Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus.
Journal of virology 2001;75(22):10746-54.
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2001: Spence P M; Sriram V; Van Kaer L; Hobbs J A; Brutkiewicz R R
Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression.
Immunology 2001;104(2):168-74.
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2001: Norbury C C; Princiotta M F; Bacik I; Brutkiewicz R R; Wood P; Elliott T; Bennink J R; Yewdell J W
Multiple antigen-specific processing pathways for activating naive CD8+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4355-62.
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2000: Grandea A G; Golovina T N; Hamilton S E; Sriram V; Spies T; Brutkiewicz R R; Harty J T; Eisenlohr L C; Van Kaer L
Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice.
Immunity 2000;13(2):213-22.
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1998: Joyce S; Woods A S; Yewdell J W; Bennink J R; De Silva A D; Boesteanu A; Balk S P; Cotter R J; Brutkiewicz R R
Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.
Science (New York, N.Y.) 1998;279(5356):1541-4.
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