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George Perry

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Jorge Durán-González; Brisa Elorza; Edna D Michi; Ian V Murray; Luis F Pacheco-Otalora; Pamela Paulson; Miriam G Perez-Córdova; George Perry; Ahmed Touhami; Luis V Colom
Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system.
Sónia C Correia; Joseph C Lamanna; Gemma Casadesus; George Perry; Maria S Santos; Renato X Santos; Mark A Smith; Paula I Moreira
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease.
Orkid Coskuner-Weber; George Perry; Olivia Wise-Scira; Taizo Kitahara
The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms.

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2013: Jorge Durán-González; Brisa Elorza; Edna D Michi; Ian V Murray; Luis F Pacheco-Otalora; Pamela Paulson; Miriam G Perez-Córdova; George Perry; Ahmed Touhami; Luis V Colom
Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system.
Neurobiology of aging 2013;34(8):2071-6.
2013: Sónia C Correia; Joseph C Lamanna; Gemma Casadesus; George Perry; Maria S Santos; Renato X Santos; Mark A Smith; Paula I Moreira
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease.
Current Alzheimer research 2013;10(4):406-19.
2013: Orkid Coskuner-Weber; George Perry; Olivia Wise-Scira; Taizo Kitahara
The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms.
ACS chemical neuroscience 2013;4(2):310-20.
2013: George Perry
The largest unmet market: chronic diseases of aging.
Mini reviews in medicinal chemistry 2013;13(1):1.
2013: George Perry; Mark A Smith; Aaron A Sorensen; Xiongwei Zhu; Jesús Avila
Preface. Alzheimer's disease: advances for a new century.
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S1.
2013: Luis V Colom; George Perry; Rodrigo O Kuljis
Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease.
Current Alzheimer research 2013;10(1):108-16.
2013: Xiongwei Zhu; George Perry; Mark A Smith; Xinglong Wang
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S253-62.
2012: Emanuel Candeias; Susana Cardoso; Cristina Carvalho; Sónia C Correia; Ana I Duarte; George Perry; Ana I Plácido; Renato X Santos; Paula I Moreira
The impairment of insulin signaling in Alzheimer's disease.
IUBMB life 2012;64(12):951-7.
2012: Steven J Greco; Ashkan Hamzelou; Jane M Johnston; George Perry; Sandy Richardson; Mark A Smith; J Wesson Ashford; Nikolaos Tezapsidis
Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest.
Current Alzheimer research 2012;9(10):1168-73.
2012: Rudy J Castellani; George Perry
Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress.
Archives of medical research 2012;43(8):694-8.
2012: Akihiko Nunomura; Rudy J Castellani; Hyoung-gon Lee; Paula I Moreira; Mark A Smith; Xiongwei Zhu; George Perry
Oxidative damage to RNA in aging and neurodegenerative disorders.
Neurotoxicity research 2012;22(3):231-48.
2012: Alessandra Piccini; Valeria Pollero; Mario Salmona; Elena Tamagno; Roberta Borghi; Sergio Cammarata; Gabriella Cirmena; Laura Colombo; Michele Fornaro; Anna Garuti; Michela Guglielmotto; Massimo Messa; George Perry; Massimo Tabaton
β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.
Journal of neurochemistry 2012;122(5):1023-31.
2012: Olivia Wise-Scira; Liang Xu; George Perry; Orkid Coskuner-Weber
Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1-40) and zinc(II)-bound amyloid-β(1-42) with dynamics.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2012;17(6):927-38.
2012: Gang Liu; Ping Men; Xiongwei Zhu; George Perry
Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease.
Therapeutic delivery 2012;3(5):571-4.
2012: Xinglong Wang; Amy Wilson-Delfosse; Michael H Yan; Gemma Casadesus; Shu G Chen; Hisashi Fujioka; Jun Liu; George Perry; Xiongwei Zhu
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1.
Human molecular genetics 2012;21(9):1931-44.
2012: Daniel J Klionsky; Jochen Klucken; Erwin Knecht; Ben C B Ko; Jan C Koch; Hiroshi Koga; Jae-Young Koh; Young Ho Koh; Masato Koike; Masaaki Komatsu; Eiki Kominami; Hee Jeong Kong; Wei-Jia Kong; Viktor I Korolchuk; Yaichiro Kotake; Michael I Koukourakis; Juan B Kouri Flores; Attila L Kovács; Claudine Kraft; Dimitri Krainc; Helmut Krämer; Carole Kretz-Remy; Anna M Krichevsky; Guido Kroemer; Rejko Krüger; Oleg Krut; Nicholas T Ktistakis; Chia-Yi Kuan; Roza Kucharczyk; Ashok Kumar; Raj Kumar; Sharad Kumar; Mondira Kundu; Hsing-Jien Kung; Tino Kurz; Ho Jeong Kwon; Albert R La Spada; Frank Lafont; Trond Lamark; Jacques Landry; Jon D Lane; Pierre Lapaquette; Jocelyn F Laporte; Lajos László; Sergio Lavandero; Josée N Lavoie; Robert Layfield; Pedro A Lazo; Laurent Le Cam; Weidong Le; Daniel J Ledbetter; Alvin J X Lee; Byung-Wan Lee; Gyun Min Lee; Jongdae Lee; Ju-Hyun Lee; Michael Lee; Myung-Shik Lee; Sug Hyung Lee; Christiaan Leeuwenburgh; Patrick Legembre; Renaud Legouis; Michael Lehmann; Huan-Yao Lei; Qun-Ying Lei; David A Leib; José Leiro; John J Lemasters; Antoinette Lemoine; Maciej S Lesniak; Dina Lev; Victor V Levenson; Beth Levine; Efrat Levy; Faqiang Li; Jun-Lin Li; Lian Li; Sheng Li; Weijie Li; Xue-Jun Li; Yan-bo Li; Yi-Ping Li; Chengyu Liang; Qiangrong Liang; Yung-Feng Liao; Pawel P Liberski; Andrew P Lieberman; Hyunjung J Lim; Kyu Lim; Kah-Leong Lim; Chiou-Feng Lin; Fu-Cheng Lin; Jian Lin; Jiandie D Lin; Kui Lin; Weei-Chin Lin; Wan-Wan Lin; Yi-Ling Lin; Rafael Linden; Paul Lingor; Jennifer Lippincott-Schwartz; Michael P Lisanti; Paloma B Liton; Bo Liu; Chun-Feng Liu; Kaiyu Liu; Leyuan Liu; Qiong A Liu; Wei Liu; Yule Liu; Young-Chau Liu; Richard A Lockshin; Chun-Nam Lok; Sagar Lonial; Benjamin Loos; Gabriel Lopez-Berestein; Carlos López-Otín; Laura Lossi; Michael T Lotze; Peter Lőw; Binfeng Lu; Bingwei Lu; Bo Lu; Zhen Lu; Frédéric Luciano; Nicholas W Lukacs; Anders H Lund; Melinda A Lynch-Day; Yong Ma; Fernando Macian; Jeffrey P MacKeigan; Kay F Macleod; Frank Madeo; Luigi Maiuri; Maria Chiara Maiuri; Davide Malagoli; May Christine V Malicdan; Walter Malorni; Na Man; Eva-Maria Mandelkow; Stéphen Manon; Irena Manov; Kai Mao; Xiang Mao; Zixu Mao; Philippe Marambaud; Daniela Marazziti; Yves L Marcel; Katie Marchbank; Piero Marchetti; Stefan Marciniak; Mateus Marcondes; Mohsen Mardi; Gabriella Marfe; Guillermo Mariño; Maria Markaki; Mark R Marten; Seamus J Martin; Camille Martinand-Mari; Wim Martinet; Marta Martinez-Vicente; Matilde Masini; Paola Matarrese; Saburo Matsuo; Raffaele Matteoni; Andreas Mayer; Nathalie M Mazure; David J McConkey; Melanie J McConnell; Catherine McDermott; Christine McDonald; Gerald M McInerney; Sharon L McKenna; BethAnn McLaughlin; Pamela J McLean; Christopher R McMaster; G Angus McQuibban; Alfred J Meijer; Miriam H Meisler; Alicia Meléndez; Thomas J Melia; Gerry Melino; Maria A Mena; Javier A Menendez; Rubem F S Menna-Barreto; Manoj B Menon; Fiona M Menzies; Carol A Mercer; Adalberto Merighi; Diane E Merry; Stefania Meschini; Christian G Meyer; Thomas F Meyer; Chao-Yu Miao; Jun-Ying Miao; Paul A M Michels; Carine Michiels; Dalibor Mijaljica; Ana Milojkovic; Saverio Minucci; Clelia Miracco; Cindy Miranti; Ioannis Mitroulis; Keisuke Miyazawa; Noboru Mizushima; Baharia Mograbi; Simin Mohseni; Xavier Molero; Bertrand Mollereau; Faustino Mollinedo; Takashi Momoi; Iryna Monastyrska; Martha M Monick; Mervyn Monteiro; Michael N Moore; Rodrigo Mora; Kevin Moreau; Paula I Moreira; Yuji Moriyasu; Jorge Moscat; Serge Mostowy; Jeremy C Mottram; Tomasz Motyl; Charbel E-H Moussa; Sylviane Muller; Sylke Müller; Karl Münger; Christian Münz; Leon O Murphy; Maureen E Murphy; Antonio Musarò; Indira Mysorekar; Eiichiro Nagata; Kazuhiro Nagata; Aimable Nahimana; Usha Nair; Toshiyuki Nakagawa; Kiichi Nakahira; Hiroyasu Nakano; Hitoshi Nakatogawa; Meera Nanjundan; Naweed I Naqvi; Derek P Narendra; Masashi Narita; Miguel Navarro; Steffan Nawrocki; Taras Y Nazarko; Andriy Nemchenko; Mihai G Netea; Thomas P Neufeld; Paul A Ney; Ioannis P Nezis; Huu Phuc Nguyen; Daotai Nie; Ichizo Nishino; Corey Nislow; Ralph A Nixon; Takeshi Noda; Angelika A Noegel; Anna Nogalska; Satoru Noguchi; Lucia Notterpek; Ivana Novak; Tomoyoshi Nozaki; Nobuyuki Nukina; Thorsten Nürnberger; Beat Nyfeler; Keisuke Obara; Terry D Oberley; Salvatore Oddo; Michinaga Ogawa; Toya Ohashi; Koji Okamoto; Nancy L Oleinick; F Javier Oliver; Laura J Olsen; Stefan Olsson; Onya Opota; Timothy F Osborne; Gary K Ostrander; Kinya Otsu; Jing-hsiung James Ou; Mireille Ouimet; Michael Overholtzer; Bulent Ozpolat; Paolo Paganetti; Ugo Pagnini; Nicolas Pallet; Glen E Palmer; Camilla Palumbo; Tianhong Pan; Theocharis Panaretakis; Udai Bhan Pandey; Zuzana Papackova; Issidora Papassideri; Irmgard Paris; Junsoo Park; Ohkmae K Park; Jan B Parys; Katherine R Parzych; Susann Patschan; Cam Patterson; Sophie Pattingre; John M Pawelek; Jianxin Peng; David H Perlmutter; Ida Perrotta; George Perry; Shazib Pervaiz; Matthias Peter; Godefridus J Peters; Morten Petersen; Goran Petrovski; James M Phang; Mauro Piacentini; Philippe Pierre; Valérie Pierrefite-Carle; Gérard Pierron; Ronit Pinkas-Kramarski; Antonio Piras; Natik Piri; Leonidas C Platanias; Stefanie Pöggeler; Marc Poirot; Angelo Poletti; Christian Poüs; Mercedes Pozuelo-Rubio; Mette Prætorius-Ibba; Anil Prasad; Mark Prescott; Muriel Priault; Nathalie Produit-Zengaffinen; Ann Progulske-Fox; Tassula Proikas-Cezanne; Serge Przedborski; Karin Przyklenk; Rosa Puertollano; Julien Puyal; Shu-Bing Qian; Liang Qin; Zheng-Hong Qin; Susan E Quaggin; Nina Raben; Hannah Rabinowich; Simon W Rabkin; Irfan Rahman; Abdelhaq Rami; Georg Ramm; Glenn Randall; Felix Randow; V Ashutosh Rao; Jeffrey C Rathmell; Brinda Ravikumar; Swapan K Ray; Bruce H Reed; John C Reed; Fulvio Reggiori; Anne Régnier-Vigouroux; Andreas S Reichert; John J Reiners; Russel J Reiter; Jun Ren; José L Revuelta; Christopher J Rhodes; Konstantinos Ritis; Elizete Rizzo; Jeffrey Robbins; Michel Roberge; Hernan Roca; Maria C Roccheri; Stephane Rocchi; H Peter Rodemann; Santiago Rodríguez de Córdoba; Bärbel Rohrer; Igor B Roninson; Kirill Rosen; Magdalena M Rost-Roszkowska; Mustapha Rouis; Kasper M A Rouschop; Francesca Rovetta; Brian P Rubin; David C Rubinsztein; Klaus Ruckdeschel; Edmund B Rucker; Assaf Rudich; Emil Rudolf; Nelson Ruiz-Opazo; Rossella Russo; Tor Erik Rusten; Kevin M Ryan; Stefan W Ryter; David M Sabatini; Junichi Sadoshima; Tapas Saha; Tatsuya Saitoh; Hiroshi Sakagami; Yasuyoshi Sakai; Ghasem Hoseini Salekdeh; Paolo Salomoni; Paul M Salvaterra; Guy Salvesen; Rosa Salvioli; Anthony M J Sanchez; José A Sánchez-Alcázar; Ricardo Sánchez-Prieto; Marco Sandri; Uma Sankar; Poonam Sansanwal; Laura Santambrogio; Shweta Saran; Sovan Sarkar; Minnie Sarwal; Chihiro Sasakawa; Ausra Sasnauskiene; Miklós Sass; Ken Sato; Miyuki Sato; Anthony H V Schapira; Michael Scharl; Hermann M Schätzl; Wiep Scheper; Stefano Schiaffino; Claudio Schneider; Marion E Schneider; Regine Schneider-Stock; Patricia V Schoenlein; Daniel F Schorderet; Christoph Schüller; Gary K Schwartz; Luca Scorrano; Linda Sealy; Per O Seglen; Juan Segura-Aguilar; Iban Seiliez; Oleksandr Seleverstov; Christian Sell; Jong Bok Seo; Duska Separovic; Vijayasaradhi Setaluri; Takao Setoguchi; Carmine Settembre; John J Shacka; Mala Shanmugam; Irving M Shapiro; Eitan Shaulian; Reuben J Shaw; James H Shelhamer; Han-Ming Shen; Wei-Chiang Shen; Zu-Hang Sheng; Yang Shi; Kenichi Shibuya; Yoshihiro Shidoji; Jeng-Jer Shieh; Chwen-Ming Shih; Yohta Shimada; Shigeomi Shimizu; Takahiro Shintani; Orian S Shirihai; Gordon C Shore; Andriy A Sibirny; Stan B Sidhu; Beata Sikorska; Elaine Silva-Zacarin; Elaine C M Silva-Zacarin; Alison Simmons; Anna Katharina Simon; Hans-Uwe Simon; Cristiano Simone; Anne Simonsen; David A Sinclair; Rajat Singh; Debasish Sinha; Frank A Sinicrope; Agnieszka Sirko; Parco M Siu; Efthimios Sivridis; Vojtech Skop; Vladimir P Skulachev; Ruth S Slack; Soraya S Smaili; Duncan Smith; Maria S Soengas; Thierry Soldati; Xueqin Song; Anil K Sood; Tuck Wah Soong; Federica Sotgia; Stephen A Spector; Claudia D Spies; Wolfdieter Springer; Srinivasa M Srinivasula; Leonidas Stefanis; Joan S Steffan; Ruediger Stendel; Harald Stenmark; Anastasis Stephanou; Stephan T Stern; Cinthya Sternberg; Björn Stork; Peter Strålfors; Carlos S Subauste; Xinbing Sui; David Sulzer; Jiaren Sun; Shi-Yong Sun; Zhi-Jun Sun; Joseph J Y Sung; Kuninori Suzuki; Toshihiko Suzuki; Michele S Swanson; Charles Swanton; Sean T Sweeney; Lai-King Sy; Gyorgy Szabadkai; Ira Tabas; Heinrich Taegtmeyer; Marco Tafani; Krisztina Takács-Vellai; Yoshitaka Takano; Kaoru Takegawa; Genzou Takemura; Fumihiko Takeshita; Nicholas J Talbot; Kevin S W Tan; Keiji Tanaka; Kozo Tanaka; Daolin Tang; Dingzhong Tang; Isei Tanida; Bakhos A Tannous; Nektarios Tavernarakis; Gregory A Taylor; Graham S Taylor; J Paul Taylor; Lance S Terada; Alexei Terman; Gianluca Tettamanti; Karin Thevissen; Craig B Thompson; Andrew Thorburn; Michael Thumm; FengFeng Tian; Yuan Tian; Glauco Tocchini-Valentini; Aviva M Tolkovsky; Yasuhiko Tomino; Lars Tönges; Sharon A Tooze; Cathy Tournier; John Tower; Roberto Towns; Vladimir Trajkovic; Leonardo H Travassos; Ting-Fen Tsai; Mario P Tschan; Takeshi Tsubata; Allan Tsung; Boris Turk; Lorianne S Turner; Suresh C Tyagi; Yasuo Uchiyama; Takashi Ueno; Midori Umekawa; Rika Umemiya-Shirafuji; Vivek K Unni; Maria I Vaccaro; Enza Maria Valente; Greet Van den Berghe; Ida J van der Klei; Wouter van Doorn; Linda F van Dyk; Marjolein van Egmond; Leo A van Grunsven; Peter Vandenabeele; Wim P Vandenberghe; Ilse Vanhorebeek; Eva C Vaquero; Guillermo Velasco; Tibor Vellai; Jose Miguel Vicencio; Richard D Vierstra; Miquel Vila; Cécile Vindis; Giampietro Viola; Maria Teresa Viscomi; Olga V Voitsekhovskaja; Clarissa von Haefen; Marcela Votruba; Keiji Wada; Richard Wade-Martins; Cheryl L Walker; Craig M Walsh; Jochen Walter; Xiang-Bo Wan; Aimin Wang; Chenguang Wang; Dawei Wang; Fan Wang; Fen Wang; Guanghui Wang; Haichao Wang; Horng-Dar Wang; Hong-Gang Wang; Jin Wang; Ke Wang; Mei Wang; Richard C Wang; Xinglong Wang; Xuejun Wang; Yipeng Wang; Ying-Jan Wang; Zhen Wang; Zhinong Wang; Zhigang Charles Wang; Derick G Wansink; Diane M Ward; Hirotaka Watada; Sarah L Waters; Paul Webster; Lixin Wei; Conrad C Weihl; William A Weiss; Scott M Welford; Long-Ping Wen; Caroline A Whitehouse; J Lindsay Whitton; Alexander J Whitworth; Tom Wileman; John W Wiley; Simon Wilkinson; Dieter Willbold; Roger L Williams; Peter R Williamson; Bradly G Wouters; Chenghan Wu; Dao-Cheng Wu; William K K Wu; Andreas Wyttenbach; Ramnik J Xavier; Zhijun Xi; Pu Xia; Gengfu Xiao; Zhiping Xie; Zhonglin Xie; Da-zhi Xu; Jianzhen Xu; Liang Xu; Xiaolei Xu; Ai Yamamoto; Akitsugu Yamamoto; Shunhei Yamashina; Michiaki Yamashita; Xianghua Yan; Mitsuhiro Yanagida; Dun-Sheng Yang; Elizabeth Yang; Jin-Ming Yang; Shi Yu Yang; Wannian Yang; Wei Yuan Yang; Zhifen Yang; Meng-Chao Yao; Tso-Pang Yao; Behzad Yeganeh; Wei-Lien Yen; Jia-jing Yin; Xiao-Ming Yin; Ook-Joon Yoo; Gyesoon Yoon; Seung-Yong Yoon; Tomohiro Yorimitsu; Yuko Yoshikawa; Tamotsu Yoshimori; Kohki Yoshimoto; Ho Jin You; Richard J Youle; Anas Younes; Li Yu; Long Yu; Seong-Woon Yu; Wai Haung Yu; Zhi-Min Yuan; Zhenyu Yue; Cheol-Heui Yun; Michisuke Yuzaki; Olga Zabirnyk; David N Zacks; Eldad Zacksenhaus; Nadia Zaffaroni; Zahra Zakeri; Herbert J Zeh; Scott O Zeitlin; Hong Zhang; Hui-Ling Zhang; Jianhua Zhang; Jing-Pu Zhang; Lin Zhang; Long Zhang; Ming-Yong Zhang; Xu Dong Zhang; Mantong Zhao; Ying Zhao; Yi-Fang Zhao; Zhizhuang J Zhao; Xiaoxiang Zheng; Boris Zhivotovsky; Qing Zhong; Cong-Zhao Zhou; Changlian Zhu; Wei-Guo Zhu; Xiongwei Zhu; Xiao-Feng Zhu; Yuangang Zhu; Teresa Zoladek; Wei-Xing Zong; Antonio Zorzano; Jürgen Zschocke; Fabio C Abdalla; Hagai Abeliovich; Robert T Abraham; Abraham Acevedo-Arozena; Khosrow Adeli; Lotta Agholme; Maria Agnello; Patrizia Agostinis; Julio A Aguirre-Ghiso; Hyung Jun Ahn; Ouardia Ait-Mohamed; Slimane Ait-Si-Ali; Takahiko Akematsu; Shizuo Akira; Matthew L Albert; Roger L Albin; Javier Alegre-Abarrategui; Maria Francesca Aleo; Mehrdad Alirezaei; alex almasan; Maylin Almonte-Becerril; Hesham M Al-Younes; Munir A Al-Zeer; Atsuo Amano; Ravi Amaravadi; Shoba Amarnath; Amal O Amer; Vellareddy Anantharam; Nathalie Andrieu-Abadie; David K Ann; Shailendra Anoopkumar-Dukie; Hiroshi Aoki; Nadezda Apostolova; Patrick Auberger; Misuzu Baba; Steven K Backues; Eric H Baehrecke; Ben A Bahr; Xue-Yuan Bai; Yannick Bailly; Robert Baiocchi; Giulia Baldini; Walter Balduini; Andrea Ballabio; Bruce A Bamber; Edward T W Bampton; Gábor Bánhegyi; Clinton R Bartholomew; Diane C Bassham; Robert C Bast; Henri Batoko; Boon-Huat Bay; Isabelle Beau; Daniel M Béchet; Thomas J Begley; Christian Behl; Christian Behrends; Soumeya Bekri; Bryan Bellaire; Linda J Bendall; Luca Benetti; Laura Berliocchi; Henri Bernardi; Francesca Bernassola; Sébastien Besteiro; Ingrid Bhatia-Kissova; Xiaoning Bi; Martine Biard-Piechaczyk; Janice S Blum; Lawrence H Boise; Paolo Bonaldo; David L Boone; Beat C Bornhauser; Karina R Bortoluci; Ioannis Bossis; Frédéric Bost; Jean-Pierre Bourquin; Patricia Boya; Michaël Boyer-Guittaut; Peter V Bozhkov; Nathan R Brady; Claudio Brancolini; Andreas Brech; Jay E Brenman; Ana Brennand; Emery H Bresnick; Patrick Brest; Dave Bridges; Molly L Bristol; Paul S Brookes; Eric J Brown; John H Brumell; Nicola Brunetti-Pierri; Ulf T Brunk; Dennis E Bulman; Scott J Bultman; Geert Bultynck; Lena F Burbulla; Wilfried Bursch; Jonathan P Butchar; Wanda Buzgariu; Sergio P Bydlowski; Ken Cadwell; Monika Cahová; Dongsheng Cai; Jiyang Cai; Qian Cai; Bruno Calabretta; Javier Calvo-Garrido; Nadine Camougrand; Michelangelo Campanella; Jenny Campos-Salinas; Eleonora Candi; Lizhi Cao; Allan B Caplan; Simon R Carding; Sandra M Cardoso; Jennifer Carew; Cathleen R Carlin; Virginie Carmignac; Leticia A M Carneiro; Serena Carra; Rosario A Caruso; Giorgio Casari; Caty Casas; Roberta Castino; Eduardo Cebollero; Francesco Cecconi; Jean Celli; Hassan Chaachouay; Han-Jung Chae; Chee-Yin Chai; David C Chan; Edmond Y Chan; Raymond Chuen-Chung Chang; Chi-Ming Che; Ching-Chow Chen; Guang-Chao Chen; Guo-Qiang Chen; Min Chen; Quan Chen; Steve S-L Chen; WenLi Chen; Xi Chen; Xiangmei Chen; Xiequn Chen; Yingyu Chen; Yongqiang Chen; Ye-Guang Chen; Yu-Jen Chen; Zhixiang Chen; Alan Cheng; Christopher H K Cheng; Yan Cheng; Heesun Cheong; Jae-Ho Cheong; Sara Cherry; Russ Chess-Williams; Zelda H Cheung; Eric Chevet; Hui-Ling Chiang; Roberto Chiarelli; Tomoki Chiba; Lih-Shen Chin; Shih-Hwa Chiou; Francis V Chisari; Chi Hin Cho; Dong-Hyung Cho; Augustine M K Choi; DooSeok Choi; Kyeong Sook Choi; Mary E Choi; Salem Chouaib; Divaker Choubey; Vinay Choubey; Charleen T Chu; Tsung-Hsien Chuang; Sheau-Huei Chueh; Taehoon Chun; Yong-Joon Chwae; Mee-Len Chye; Roberto Ciarcia; Maria R Ciriolo; Michael J Clague; Robert S B Clark; Peter G H Clarke; Robert Clarke; Patrice Codogno; Hilary A Coller; María I Colombo; Sergio Comincini; Maria Condello; Fabrizio Condorelli; Mark R Cookson; Graham H Coombs; Isabelle Coppens; Ramon Corbalan; Pascale Cossart; Paola Costelli; Safia Costes; Ana Coto-Montes; Eduardo Couve; Fraser P Coxon; James M Cregg; José L Crespo; Marianne J Cronjé; Ana Maria Cuervo; Joseph J Cullen; Mark J Czaja; Marcello D'Amelio; Arlette Darfeuille-Michaud; Lester M Davids; Faith E Davies; Massimo De Felici; John F de Groot; Cornelis A M de Haan; Luisa De Martino; Angelo De Milito; Vincenzo De Tata; Jayanta Debnath; Alexei Degterev; Benjamin Dehay; Lea M D Delbridge; Francesca Demarchi; Yi Zhen Deng; Jörn Dengjel; Paul Dent; Donna Denton; Vojo Deretic; Shyamal D Desai; Rodney J Devenish; Mario Di Gioacchino; Gilbert Di Paolo; Chiara Di Pietro; Guillermo Díaz-Araya; Inés Díaz-Laviada; Maria T Diaz-Meco; Javier Diaz-Nido; Ivan Dikic; Savithramma P Dinesh-Kumar; Wen-Xing Ding; Clark W Distelhorst; Abhinav Diwan; Mojgan Djavaheri-Mergny; Svetlana Dokudovskaya; Zheng Dong; Frank C Dorsey; Victor Dosenko; James Dowling; Stephen Doxsey; Marlène Dreux; Mark E Drew; Qiuhong Duan; Michel A Duchosal; Karen Duff; Isabelle Dugail; Madeleine Durbeej; Michael Duszenko; Charles L Edelstein; Aimee L Edinger; Gustavo Egea; Ludwig Eichinger; N Tony Eissa; Suhendan Ekmekcioglu; Zvulun Elazar; Wafik S El-Deiry; Mohamed Elgendy; Lisa M Ellerby; Kai Er Eng; Anna-Mart Engelbrecht; Simone Engelender; Jekaterina Erenpreisa; Ricardo Escalante; Audrey Esclatine; Eeva-Liisa Eskelinen; Lucile Espert; Virginia Espina; Huizhou Fan; Jia Fan; Qi-Wen Fan; Zhen Fan; Shengyun Fang; Yongqi Fang; Manolis Fanto; Alessandro Fanzani; Thomas Farkas; Jean-Claude Farré; Mathias Faure; Marcus Fechheimer; Carl G Feng; Jian Feng; Qili Feng; Youji Feng; László Fésüs; Ralph Feuer; Maria E Figueiredo-Pereira; Gian Maria Fimia; Diane C Fingar; Steven Finkbeiner; TOREN FINKEL; Kim D Finley; Filomena Fiorito; Edward A Fisher; Paul B Fisher; Marc Flajolet; Maria L Florez-McClure; Salvatore Florio; Edward A Fon; Francesco Fornai; Franco Fortunato; Rati Fotedar; Daniel H Fowler; Howard S Fox; Rodrigo Franco; Lisa B Frankel; Marc Fransen; José M Fuentes; Juan Fueyo; Jun Fujii; Kozo Fujisaki; Eriko Fujita; Mitsunori Fukuda; Ruth H Furukawa; Matthias Gaestel; Philippe Gailly; Malgorzata Gajewska; Brigitte Galliot; Vincent Galy; Subramaniam Ganesh; Barry Ganetzky; Ian G Ganley; Fen-Biao Gao; George F Gao; Jinming Gao; Lorena Garcia; Guillermo Garcia-Manero; Mikel Garcia-Marcos; Marjan Garmyn; Andrei L Gartel; Evelina Gatti; Mathias Gautel; Thomas R Gawriluk; Matthew E Gegg; Jiefei Geng; Marc Germain; Jason E Gestwicki; David A Gewirtz; Saeid Ghavami; Pradipta Ghosh; Anna M Giammarioli; Alexandra N Giatromanolaki; Spencer B Gibson; Robert W Gilkerson; Michael L Ginger; Ebru Goncu; Céline Gongora; Claudio D Gonzalez; Ramon Gonzalez; Cristina González-Estévez; Rosa Ana González-Polo; Elena Gonzalez-Rey; Nikolai V Gorbunov; Sharon Gorski; Sandro Goruppi; Roberta A Gottlieb; Devrim Gozuacik; Giovanna Elvira Granato; Gary D Grant; Kim N Green; Aleš Gregorc; Frédéric Gros; Charles Grose; Thomas W Grunt; Philippe Gual; Jun-Lin Guan; Kun-Liang Guan; Sylvie M Guichard; Anna S Gukovskaya; Ilya Gukovsky; Jan Gunst; Asa B Gustafsson; Andrew J Halayko; Amber N Hale; Sandra K Halonen; Maho Hamasaki; Feng Han; Ting Han; Michael K Hancock; Malene Hansen; Hisashi Harada; Masaru Harada; Stefan E Hardt; J Wade Harper; Adrian L Harris; James Harris; Steven D Harris; Marie-Joseé Hébert; Kim A Heidenreich; Miep H Helfrich; Gudmundur V Helgason; Elizabeth P Henske; Brian Herman; Paul K Herman; Claudio Hetz; Sabine Hilfiker; Joseph A Hill; Lynne J Hocking; Paul Hofman; Thomas G Hofmann; Jörg Höhfeld; Tessa L Holyoake; Ming-Huang Hong; David A Hood; Gökhan S Hotamisligil; Ewout J Houwerzijl; Maria Høyer-Hansen; Bingren Hu; Chien-An A Hu; Hong-Ming Hu; Ya Hua; Canhua Huang; Ju Huang; Shengbing Huang; Wei-Pang Huang; Tobias B Huber; Won-Ki Huh; Tai-Ho Hung; Ted R Hupp; Gang Min Hur; James B Hurley; Sabah N A Hussain; Patrick J Hussey; Jung Jin Hwang; Seungmin Hwang; Atsuhiro Ichihara; Shirin Ilkhanizadeh; Ken Inoki; Takeshi Into; Valentina Iovane; Juan L Iovanna; Nancy Y Ip; Yoshitaka Isaka; Hiroyuki Ishida; Ciro Isidoro; Ken-ichi Isobe; Akiko Iwasaki; Marta Izquierdo; Yotaro Izumi; Panu M Jaakkola; Marja Jäättelä; George R Jackson; William T Jackson; Bassam Janji; Marina Jendrach; Ju-Hong Jeon; Eui-Bae Jeung; Hong Jiang; Hongchi Jiang; Jean X Jiang; Ming Jiang; Qing Jiang; Xuejun Jiang; Xuejun Jiang; Alberto Jiménez; Meiyan Jin; Shengkan Jin; Cheol O Joe; Terje Johansen; Daniel E Johnson; Gail V W Johnson; Nicola L Jones; Bertrand Joseph; Suresh K Joseph; Annie M Joubert; Gábor Juhász; Lucienne Juillerat-Jeanneret; Chang Hwa Jung; Yong-Keun Jung; Kai Kaarniranta; Allen Kaasik; Tomohiro Kabuta; Motoni Kadowaki; Katarina Kagedal; Yoshiaki Kamada; Vitaliy O Kaminskyy; Harm H Kampinga; Hiromitsu Kanamori; Chanhee Kang; Khong Bee Kang; Kwang Il Kang; Rui Kang; Yoon-A Kang; Tomotake Kanki; Thirumala-Devi Kanneganti; Haruo Kanno; Arthi Kanthasamy; Anumantha G Kanthasamy; Vassiliki Karantza; Gur P Kaushal; Susmita Kaushik; Yoshinori Kawazoe; Po-Yuan Ke; John H Kehrl; Ameeta Kelekar; Claus Kerkhoff; David Kessel; Hany Khalil; Jan A K W Kiel; Amy A Kiger; Akio Kihara; Do-Hyung Kim; Dong-Hou Kim; Deok Ryong Kim; Eun-Kyoung Kim; Hyung-Ryong Kim; Jin Cheon Kim; Jeong Hun Kim; John K Kim; Jae-Sung Kim; Peter K Kim; Seong Who Kim; Yonghyun Kim; Yong-Sun Kim; Adi Kimchi; Alec C Kimmelman; Jason S King; Timothy J Kinsella; Vladimir Kirkin; Lorrie A Kirshenbaum; Katsuhiko Kitamoto; Kaio Kitazato; Ludger Klein; Walter T Klimecki; Giuseppe Arancia; John P Aris; Katsuhiko Asanuma; Nana Y O Asare; Hisashi Ashida; Valerie Askanas; David S Askew; Henry N Ginsberg; Jakub Golab; Michael S Goligorsky; Pierre Golstein; Candelaria Gomez-Manzano; Makoto Hashimoto; Jeffrey A Haspel; Shin-ichiro Hayashi; Lori A Hazelhurst; Congcong He; You-Wen He; Brian Zuckerbraun
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy 2012;8(4):445-544.
2012: Renato X Santos; Mark A Smith; Xiongwei Zhu; Sónia C Correia; Hyoung-gon Lee; Akihiko Nunomura; George Perry; Robert B Petersen; Paula I Moreira
Nuclear and mitochondrial DNA oxidation in Alzheimer's disease.
Free radical research 2012;46(4):565-76.
2012: Rudy J Castellani; Paula I Moreira; George Perry; Xiongwei Zhu
The role of iron as a mediator of oxidative stress in Alzheimer disease.
BioFactors (Oxford, England) 2012;38(2):133-8.
2012: Akihiko Nunomura; George Perry; Mark A Smith; Massimo Tabaton; Toshio Tamaoki; Hyoung-gon Lee; Daniel W McKeel; Nobutaka Motohashi; Masao Nakamura; Xiongwei Zhu
The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.
Journal of neuropathology and experimental neurology 2012;71(3):233-41.
2012: Xiongwei Zhu; Nicholas P Ziats; Rudy J Castellani; Hyoung Gon Lee; Robert B Petersen; George Perry
Mark A. Smith: neurocytochemistry innovator.
Journal of neurochemistry 2012;120(6):1139-40.
2012: Wataru Kudo; Hyun-Pil Lee; George Perry; Robert B Petersen; Mark A Smith; Xinglong Wang; Xiongwei Zhu; Wen-Quan Zou; Hyoung-gon Lee
Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.
Human molecular genetics 2012;21(5):1138-44.
2012: David J Bonda; Gang Liu; Ping Men; George Perry; Mark A Smith; Xiongwei Zhu
Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!
CNS & neurological disorders drug targets 2012;11(1):81-5.
2012: Xiongwei Zhu; Gjumrakch Aliev; Rudy J Castellani; Hisashi Fujioka; Peggy L R Harris; Paula I Moreira; Lawrence M Sayre; Justin Shenk; Sandra L Siedlak; Mark A Smith; Luke I Szweda; Pamela A Szweda; George Perry
Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Free radical biology & medicine 2012;52(3):699-704.
2012: Baiyang Sheng; Hyoung-gon Lee; Gemma Casadesus; Xinglong Wang; George Perry; Bo Su; Xiongwei Zhu
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease.
Journal of neurochemistry 2012;120(3):419-29.
2012: Judith Miklossy; Kurt Mueller; Oliver J. Nolte; Samuel Donta; George Perry
Chronic or late lyme neuroborreliosis: present and future.
The open neurology journal 2012;6():78.
2012: Laura Morelli; George Perry; Fabrizio Tagliavini
The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview.
International journal of Alzheimer's disease 2012;2012():709613.
2012: Siddhartha Mondragón-Rodríguez; Paula I Moreira; George Perry; Xiongwei Zhu; Sylvain Williams
Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?
International journal of Alzheimer's disease 2012;2012():276803.
2012: Wesley M Williams; Aaron Weinberg; Rudy J Castellani; George Perry; Mark A Smith
Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?
TheScientificWorldJournal 2012;2012():905785.
2012: Siddhartha Mondragón-Rodríguez; George Perry; Xiongwei Zhu; Jannic Boehm
Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy.
International journal of Alzheimer's disease 2012;2012():630182.
2012: Sónia C Correia; Paula I Moreira; George Perry; Renato X Santos; Xiongwei Zhu; Mark A Smith
Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases.
Advances in experimental medicine and biology 2012;724():205-21.
2012: Arlene Reed-Cossairt; Xiongwei Zhu; Hyoung-gon Lee; George Perry; Charles Reed; Robert B Petersen
Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome.
Current gerontology and geriatrics research 2012;2012():929734.
2012: George Perry; Robert B Petersen; CF Phelix; Rudy J Castellani; Luis V Colom; Hyoung-gon Lee; Akihiko Nunomura; Xiongwei Zhu
Untangling the vascular web from Alzheimer disease and oxidative stress.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2012;39(1):4.
2012: George Perry
Editorial: a new era for medicinal chemistry.
Mini reviews in medicinal chemistry 2012;12(1):1.
2012: Lilian Calderón-Garcidueñas; Amedeo D'Angiulli; Ricardo Delgado-Chávez; Michelle Block; Angelica González-Maciel; Ruixin Guo; Zhaowei Hua; Michael Kavanaugh; Norma Osnaya; George Perry; Rafael Reynoso-Robles; Ricardo Torres-Jardón; Rodolfo Villarreal-Calderon; Hongtu Zhu; Philippe Diaz
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults.
Journal of Alzheimer's disease : JAD 2012;28(1):93-107.
2012: Michela Guglielmotto; Claudio Medana; George Perry; Mark A Smith; Manuela Aragno; Giuseppe Boccuzzi; Maria G Catalano; Oliviero Danni; Elena Tamagno; Ilenia Vercellinatto; Sonja Visentin; Massimo Tabaton
AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation.
Neurobiology of aging 2012;33(1):196.e13-27.
2011: Luis V Colom; Maria T Castaneda; Saul Jaime; Sofia Hernandez; George Perry; Ahmed Touhami
Intrahippocampal amyloid-β (1-40) injections injure medial septal neurons in rats.
Current Alzheimer research 2011;8(8):832-40.
2011: Rudy J Castellani; Jeff M Coller; Yashi Gupta; Peggy Lr Harris; Hyoung-gon Lee; George Perry; Baiyang Sheng; Sandra L Siedlak; Mark A Smith; Massimo Tabaton; Xinglong Wang; Xiongwei Zhu
A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
Laboratory investigation; a journal of technical methods and pathology 2011;91(12):1777-86.
2011: Olivia Wise-Scira; Liang Xu; Taizo Kitahara; George Perry; Orkid Coskuner-Weber
Amyloid-β peptide structure in aqueous solution varies with fragment size.
The Journal of chemical physics 2011;135(20):205101.
2011: Rudy J Castellani; Hyoung-gon Lee; Robert B Petersen; Xiongwei Zhu; George Perry
Mark A. Smith: the scientist, the man.
International journal of experimental pathology 2011;92(5):297-8.
2011: Xinglong Wang; Rudy J Castellani; Yuan Gao; Xiaohua He; Wanhong Liu; George Perry; Mark A. Smith; Bo Su; Xiongwei Zhu
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease.
Aging cell 2011;10(5):807-23.
2011: D J Bonda; A Nunomura; George Perry; X Zhu; Rudy J Castellani; H-g Lee; M A Smith
A novel perspective on tau in Alzheimer's disease.
Current Alzheimer research 2011;8(6):639-42.
2011: Jeremy G Stone; Massimo Tabaton; Xiongwei Zhu; Rudy J Castellani; Asao Hirano; George Perry; Corrado Santocanale; Sandra L Siedlak; Mark A. Smith; Hyoung-gon Lee
The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
Journal of neuropathology and experimental neurology 2011;70(7):578-87.
2011: Christopher M Valdez; CF Phelix; Mark A. Smith; George Perry; Fidel Santamaria
Modeling cholesterol metabolism by gene expression profiling in the hippocampus.
Molecular bioSystems 2011;7(6):1891-901.
2011: Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A. Smith
Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?
Ageing research reviews 2011;10(2):264-73.
2011: David J Bonda; Hyoung-gon Lee; Jeffrey A Blair; Xiongwei Zhu; George Perry; Mark A. Smith
Role of metal dyshomeostasis in Alzheimer's disease.
Metallomics : integrated biometal science 2011;3(3):267-70.
2011: Nicholas P Ziats; Rudy J Castellani; Hyoung-gon Lee; George Perry; Robert B Petersen; Xiongwei Zhu
Mark A. Smith, 1965-2010: consummate student of pathogenesis.
International journal of clinical and experimental pathology 2011;4(7):731-2.
2011: J Wesson Ashford; Peter Bayley; Sandra Black; Kerry L Coburn; Steven D Edland; Giovanni B Frisoni; Ansgar Furst; Clifford R Jack; David Kennedy; John M Olichney; Allyson Rosen; Osama Sabri; Ahmad Salehi; Norbert Schuff; Daniel Spielman; Michael Weiner; Maheen M Adamson; George Perry
Imaging the Alzheimer brain.
Journal of Alzheimer's disease : JAD 2011;26 Suppl 3():1-27.
2011: Quan Liu; Paula I Moreira; Mark A. Smith; Fang Xie; Xiongwei Zhu; Abdiel Alvarado-Diaz; George Perry
Neurofilamentopathy in neurodegenerative diseases.
The open neurology journal 2011;5():58-62.
2011: David J Bonda; Hyoung-gon Lee; George Perry; Mark A Smith; Xinglong Wang; Xiongwei Zhu
The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention.
Current pharmaceutical design 2011;17(31):3374-80.
2011: Sónia C Correia; Susana Cardoso; Cristina Carvalho; George Perry; Maria S Santos; Renato X Santos; Mark A Smith; Paula I Moreira
New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection.
Current pharmaceutical design 2011;17(31):3381-9.
2011: Jeremy G Stone; Xinglong Wang; Xiongwei Zhu; Gemma Casadesus Smith; Rudy J Castellani; Kasia Gustaw-Rothenberg; George Perry; Sandra L Siedlak; Mark A Smith
Frontiers in Alzheimer's disease therapeutics.
Therapeutic advances in chronic disease 2011;2(1):9-23.
2011: Gabriel B Britton; Mark A. Smith; George Perry; Kumar Sambamurti; K S Jagannatha Rao
Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24 Suppl 2():1-2.
2011: George Perry; Xiongwei Zhu
Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease.
Journal of Alzheimer's disease : JAD 2011;24(1):1-2.
2011: Rudy J Castellani; Summer L Nugent; AL Morrison; Xiongwei Zhu; Hyoung-gon Lee; Peggy L R Harris; Vladan Bajić; Hari S Sharma; Shu G Chen; Peter Oettgen; George Perry; Mark A. Smith
CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(1):23-6.
2010: Gavin A Buxton; Sandra L Siedlak; George Perry; Mark A. Smith
Mathematical modeling of microtubule dynamics: insights into physiology and disease.
Progress in neurobiology 2010;92(4):478-83.
2010: Jonathon E Heath; Sandra L Siedlak; Xiongwei Zhu; Hyoung-gon Lee; Akanksha Thakur; Riqiang Yan; George Perry; Mark A. Smith; Rudy J Castellani
Widespread distribution of reticulon-3 in various neurodegenerative diseases.
Neuropathology : official journal of the Japanese Society of Neuropathology 2010;30(6):574-9.
2010: Barney E Dwyer; Leo R Zacharski; Dominic J Balestra; Alan J Lerner; George Perry; Xiongwei Zhu; Mark A. Smith
Potential role of iron in a Mediterranean-style diet.
Archives of neurology 2010;67(10):1286-7; author reply 1287-8.
2010: David J Bonda; Xinglong Wang; George Perry; Akihiko Nunomura; Massimo Tabaton; Xiongwei Zhu; Mark A. Smith
Oxidative stress in Alzheimer disease: a possibility for prevention.
Neuropharmacology 2010;59(4-5):290-4.
2010: Wen-Quan Zou; Gianfranco Puoti; Xiangzhu Xiao; Jue Yuan; Liuting Qing; Ignazio Cali; Miyuki Shimoji; Jan P M Langeveld; Rudy J Castellani; Silvio Notari; Barbara J Crain; Robert E Schmidt; Michael Geschwind; Stephen J DeArmond; Nigel J Cairns; dennis dickson; Lawrence Honig; Juan Maria Torres; James A Mastrianni; Sabina Capellari; Giorgio Giaccone; Ermias D Belay; Lawrence B Schonberger; Mark Cohen; George Perry; Qingzhong Kong; Piero Parchi; Fabrizio Tagliavini; Pierluigi Gambetti
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
Annals of neurology 2010;68(2):162-72.
2010: Chris M Valdez; Mark A. Smith; George Perry; CF Phelix; Fidel Santamaria
Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers.
Hippocampus 2010;20(8):902-5.
2010: Calvin F Moh; Sandra L Siedlak; Massimo Tabaton; George Perry; Rudy J Castellani; Mark A. Smith
Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease.
Journal of neuroscience methods 2010;190(2):244-7.
2010: Daniela Storace; Sergio Cammarata; Roberta Borghi; Roberta Sanguineti; Luca Giliberto; Alessandra Piccini; Valeria Pollero; Cristina Novello; Carlo Caltagirone; Mark A. Smith; Paola Bossù; George Perry; Patrizio Odetti; Massimo Tabaton
Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment.
Archives of neurology 2010;67(7):867-72.
2010: Paula I Moreira; Renato X Santos; Xiongwei Zhu; Hyoung-gon Lee; Mark A. Smith; Gemma Casadesus; George Perry
Autophagy in Alzheimer's disease.
Expert review of neurotherapeutics 2010;10(7):1209-18.
2010: Hyun Pil Lee; Xiongwei Zhu; Gemma Casadesus; Rudy J Castellani; Akihiko Nunomura; Mark A. Smith; Hyoung-gon Lee; George Perry
Antioxidant approaches for the treatment of Alzheimer's disease.
Expert review of neurotherapeutics 2010;10(7):1201-8.
2010: Masao Nakamura; Naomi Shishido; Akihiko Nunomura; Mark A. Smith; George Perry; Hiroaki Akutsu; Takaaki Hayashi
Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid.
Free radical research 2010;44(7):734-41.
2010: Bo Su; Xinglong Wang; David Bonda; George Perry; Mark A. Smith; Xiongwei Zhu
Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?
Molecular neurobiology 2010;41(2-3):87-96.
2010: Siddhartha Mondragón-Rodríguez; Gustavo Basurto-Islas; Hyoung-gon Lee; George Perry; Xiongwei Zhu; Rudy J Castellani; Mark A. Smith
Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.
Expert review of neurotherapeutics 2010;10(5):683-91.
2010: Hyun-pil Lee; Xiongwei Zhu; Gang Liu; Shu G Chen; George Perry; Mark A. Smith; Hyoung-gon Lee
Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship.
Cell research 2010;20(4):397-9.
2010: David J Bonda; Xinglong Wang; George Perry; Mark A. Smith; Xiongwei Zhu
Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies.
Drugs & aging 2010;27(3):181-92.
2010: David J Bonda; Hyun-Pil Lee; Hyoung-gon Lee; Avi L Friedlich; George Perry; Xiongwei Zhu; Mark A. Smith
Novel therapeutics for Alzheimer's disease: an update.
Current opinion in drug discovery & development 2010;13(2):235-46.
2010: Akihiko Nunomura; Toshio Tamaoki; Koich Tanaka; Nobutaka Motohashi; Masao Nakamura; Takaaki Hayashi; Haruyasu Yamaguchi; Shun Shimohama; Hyoung-gon Lee; Xiongwei Zhu; Mark A. Smith; George Perry
Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.
Neurobiology of disease 2010;37(3):731-7.
2010: Katarzyna Gustaw-Rothenberg; Alan Lerner; David J Bonda; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A. Smith
Biomarkers in Alzheimer's disease: past, present and future.
Biomarkers in medicine 2010;4(1):15-26.
2010: Massimo Tabaton; George Perry; Xiongwei Zhu; Hyoung-gon Lee; Gemma Casadesus; Mark A. Smith
Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.
The American journal of pathology 2010;176(2):540-1.
2010: Bo Su; Xinglong Wang; Hyoung-gon Lee; Massimo Tabaton; George Perry; Mark A. Smith; Xiongwei Zhu
Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells.
Neuroscience letters 2010;468(3):267-71.
2010: Roberta Borghi; Alessandra Piccini; Erica Barini; Gabriella Cirmena; Michela Guglielmotto; Elena Tamagno; Michele Fornaro; George Perry; Mark A. Smith; Anna Garuti; Massimo Tabaton
Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(3):771-5.
2010: Sónia C Correia; cristina carvalho; Susana Cardoso; Renato X Santos; Maria S Santos; Catarina R Oliveira; George Perry; Xiongwei Zhu; Mark A. Smith; Paula I Moreira
Mitochondrial preconditioning: a potential neuroprotective strategy.
Frontiers in aging neuroscience 2010;2():.
2010: David J Bonda; Maneesh Mailankot; Jeremy G Stone; Matthew R Garrett; Magdalena Staniszewska; Rudy J Castellani; Sandra L Siedlak; Xiongwei Zhu; Hyoung-gon Lee; George Perry; Ram H Nagaraj; Mark A. Smith
Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
Redox report : communications in free radical research 2010;15(4):161-8.
2010: Renato X Santos; Sónia C Correia; Xinglong Wang; George Perry; Mark A. Smith; Paula I Moreira; Xiongwei Zhu
Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.
International journal of clinical and experimental pathology 2010;3(6):570-81.
2010: Jesús Avila; George Perry; Pablo Martínez-Martín
Prospects on the origin of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;20(2):669-72.
2010: Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A. Smith
Mitochondria: the missing link between preconditioning and neuroprotection.
Journal of Alzheimer's disease : JAD 2010;20 Suppl 2():S475-85.
2010: Renato X Santos; Sónia C Correia; Xinglong Wang; George Perry; Mark A. Smith; Paula I Moreira; Xiongwei Zhu
A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;20 Suppl 2():S401-12.
2010: Burkhard Poeggeler; Kumar Sambamurti; Sandra L Siedlak; George Perry; Mark A. Smith; Miguel A Pappolla
A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan.
PloS one 2010;5(4):e10206.
2010: Nanditha G Nair; George Perry; Mark A. Smith; V Prakash Reddy
NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide.
Journal of Alzheimer's disease : JAD 2010;20(1):57-66.
2010: Xinglong Wang; George Perry; Mark A. Smith; Xiongwei Zhu
Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons.
Neuro-degenerative diseases 2010;7(1-3):56-9.
2010: Mark A. Smith; Xiongwei Zhu; Massimo Tabaton; Gang Liu; Daniel W McKeel; Mark L Cohen; Xinglong Wang; Sandra L Siedlak; Barney E Dwyer; Takaaki Hayashi; Masao Nakamura; Akihiko Nunomura; George Perry
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment.
Journal of Alzheimer's disease : JAD 2010;19(1):363-72.
2010: Paula I Moreira; Lawrence M Sayre; Xiongwei Zhu; Akihiko Nunomura; Mark A. Smith; George Perry
Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
Methods in molecular biology (Clifton, N.J.) 2010;610():419-34.
2010: Gang Liu; Ping Men; George Perry; Mark A. Smith
Nanoparticle and iron chelators as a potential novel Alzheimer therapy.
Methods in molecular biology (Clifton, N.J.) 2010;610():123-44.
2010: Paula I Moreira; cristina carvalho; Xiongwei Zhu; Mark A. Smith; George Perry
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology.
Biochimica et biophysica acta 2010;1802(1):2-10.
2010: Paula I Moreira; Xiongwei Zhu; Xinglong Wang; Hyoung-gon Lee; Akihiko Nunomura; Robert B Petersen; George Perry; Mark A. Smith
Mitochondria: a therapeutic target in neurodegeneration.
Biochimica et biophysica acta 2010;1802(1):212-20.
2010: Katarzyna A Gustaw-Rothenberg; Sandra L Siedlak; David J Bonda; Alan Lerner; Massimo Tabaton; George Perry; Mark A. Smith
Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study.
Experimental gerontology 2010;45(1):47-52.
2010: Bo Su; Xinglong Wang; Ling Zheng; George Perry; Mark A. Smith; Xiongwei Zhu
Abnormal mitochondrial dynamics and neurodegenerative diseases.
Biochimica et biophysica acta 2010;1802(1):135-42.
2010: Massimo Tabaton; Xiongwei Zhu; George Perry; Mark A. Smith; Luca Giliberto
Signaling effect of amyloid-beta(42) on the processing of AbetaPP.
Experimental neurology 2010;221(1):18-25.
2009: George Perry; Paula I Moreira; Sandra L Siedlak; Akihiko Nunomura; Xiongwei Zhu; Mark A. Smith
Natural oxidant balance in Parkinson disease.
Archives of neurology 2009;66(12):1445.
2009: Hyun-Pil Lee; Gemma Casadesus Smith; Xiongwei Zhu; Hyoung-gon Lee; George Perry; Mark A. Smith; Katarzyna Gustaw-Rothenberg; Alan Lerner
All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease.
Expert review of neurotherapeutics 2009;9(11):1615-21.
2009: Barbara J Crain; Robert D Terry; George Perry
2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD.
Journal of neuropathology and experimental neurology 2009;68(11):1244-6.
2009: cristina carvalho; Sónia C Correia; Renato X Santos; Susana Cardoso; Paula I Moreira; Timothy A Clark; Xiongwei Zhu; Mark A. Smith; George Perry
Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.
Journal of bioenergetics and biomembranes 2009;41(5):433-40.
2009: Barney E Dwyer; Meghan L Stone; Nadia Gorman; Peter R Sinclair; George Perry; Mark A. Smith; Xiongwei Zhu
Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
Neuroscience letters 2009;461(3):302-5.
2009: Barney E Dwyer; Mark A. Smith; Sandy L Richardson; George Perry; Xiongwei Zhu
Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.
Neuroscience letters 2009;460(2):180-4.
2009: Xinglong Wang; Bo Su; Hyoung-gon Lee; Xinyi Li; George Perry; Mark A. Smith; Xiongwei Zhu
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(28):9090-103.
2009: Akihiko Nunomura; Tim Hofer; Paula I Moreira; Rudy J Castellani; Mark A. Smith; George Perry
RNA oxidation in Alzheimer disease and related neurodegenerative disorders.
Acta neuropathologica 2009;118(1):151-66.
2009: Mar Perez; Ismael Santa-Maria; Elena Gomez de Barreda; Xiongwei Zhu; Raquel Cuadros; Jose Roman Cabrero; Francisco Sanchez-Madrid; Hana N. Dawson; Michael P. Vitek; George Perry; Mark A. Smith; Jesús Avila
Tau--an inhibitor of deacetylase HDAC6 function.
Journal of neurochemistry 2009;109(6):1756-66.
2009: Gang Liu; Ping Men; Wataru Kudo; George Perry; Mark A. Smith
Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease.
Neuroscience letters 2009;455(3):187-90.
2009: Xinglong Wang; Bo Su; Ling Zheng; George Perry; Mark A. Smith; Xiongwei Zhu
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Journal of neurochemistry 2009;109 Suppl 1():153-9.
2009: Mark E Obrenovich; Ludis A Morales; Celia J Cobb; Justin Shenk; Gina M Méndez; Kathryn Fischbach; Mark A. Smith; Eldar K Qasimov; George Perry; Gjumrakch Aliev
Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation.
Journal of cellular and molecular medicine 2009;13(5):853-65.
2009: Barney E Dwyer; Leo R Zacharski; Dominic J Balestra; Alan J Lerner; George Perry; Xiongwei Zhu; Mark A. Smith
Getting the iron out: phlebotomy for Alzheimer's disease?
Medical hypotheses 2009;72(5):504-9.
2009: Reshmi Rajendran; Ren Minqin; Maria Dolores Ynsa; Gemma Casadesus Smith; Mark A. Smith; George Perry; Barry Halliwell; Frank Watt
A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease.
Biochemical and biophysical research communications 2009;382(1):91-5.
2009: David J Bonda; Teresa A Evans; Corrado Santocanale; Jesús Catalá Llosá; Jose Viña; Bajic Vladan; Rudy J Castellani; Sandra L Siedlak; George Perry; Mark A. Smith; Hyoung-gon Lee
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
Aging 2009;1(4):382-8.
2009: Rudy J Castellani; Xiongwei Zhu; Hyoung-gon Lee; Mark A. Smith; George Perry
Molecular pathogenesis of Alzheimer's disease: Reductionist versus expansionist approaches.
International journal of molecular sciences 2009;10(3):1386-406.
2009: Hyun-Pil Lee; Xiongwei Zhu; Xiaochun Zhu; S Chad Skidmore; George Perry; Lawrence M Sayre; Mark A. Smith; Hyoung-gon Lee
The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 2009;108(6):1434-41.
2009: Hyoung-gon Lee; Gemma Casadesus Smith; Akihiko Nunomura; Xiongwei Zhu; Rudy J Castellani; Sandy L Richardson; George Perry; Dean W Felsher; Robert B Petersen; Mark A. Smith
The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
The American journal of pathology 2009;174(3):891-7.
2009: George Perry; Xiongwei Zhu; Paula I Moreira; Mark A. Smith
Altered redox balance in disease: can we change the new equilibria?
Annals of neurology 2009;65(2):121-3.
2009: Michela Guglielmotto; Manuela Aragno; Riccardo Autelli; Luca Giliberto; Erica Novo; Sebastiano Colombatto; Oliviero Danni; Maurizio Parola; Mark A. Smith; George Perry; Elena Tamagno; Massimo Tabaton
The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.
Journal of neurochemistry 2009;108(4):1045-56.
2009: Sandra L Siedlak; Gemma Casadesus Smith; Kate M Webber; Miguel Pappolla; Craig S Atwood; Mark A. Smith; George Perry
Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.
Free radical research 2009;43(2):156-64.
2009: Hyoung-gon Lee; Gemma Casadesus Smith; Xiongwei Zhu; Rudy J Castellani; Andy McShea; George Perry; Robert B Petersen; Bajic Vladan; Mark A. Smith
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
Neurochemistry international 2009;54(2):84-8.
2009: Emma Ramiro-Puig; Gemma Casadesús; Hyoung-gon Lee; Xiongwei Zhu; Andy McShea; George Perry; Francisco J Pérez-Cano; Mark A. Smith; Margarida Castell
Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress.
European journal of nutrition 2009;48(1):54-61.
2009: Gjumrakch Aliev; Jiankang Liu; Justin Shenk; Kathryn Fischbach; Gerardo J Pacheco; Shu G Chen; Mark E Obrenovich; Walter F Ward; Arlan G Richardson; Mark A. Smith; Eldar Gasimov; George Perry; Bruce N Ames
Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.
Journal of cellular and molecular medicine 2009;13(2):320-33.
2009: Hyoung-gon Lee; Xiongwei Zhu; Gemma Casadesus Smith; Merce Pallas; Antoni Camins; Michael J O'Neill; Shigetada Nakanishi; George Perry; Mark A. Smith
The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival.
Brain research 2009;1249():244-50.
2009: Avi L Friedlich; Raj K Rolston; Xiongwei Zhu; Michael W Marlatt; Rudy J Castellani; Akihiko Nunomura; Hyoung-gon Lee; Gemma Casadesus; George Perry; Mark A. Smith
Treatment advances in Alzheimer's disease based on the oxidative stress model.
F1000 medicine reports 2009;1():.
2009: Gang Liu; Ping Men; George Perry; Mark A. Smith
Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease.
Progress in brain research 2009;180():97-108.
2009: Bo Su; Haihua Liu; Xinglong Wang; Shu G Chen; Sandra L Siedlak; Eisaku Kondo; Raymond Choi; Atsushi Takeda; Rudy J Castellani; George Perry; Mark A. Smith; Xiongwei Zhu; Hyoung-gon Lee
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease.
Molecular neurodegeneration 2009;4():32.
2009: Rudy J Castellani; Hyoung-gon Lee; Sandra L Siedlak; Akihiko Nunomura; Takaaki Hayashi; Masao Nakamura; Xiongwei Zhu; George Perry; Mark A. Smith
Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.
Journal of Alzheimer's disease : JAD 2009;18(2):447-52.
2009: Susana Cardoso; Sónia Correia; Renato X Santos; cristina carvalho; Maria S Santos; Catarina R Oliveira; George Perry; Mark A. Smith; Xiongwei Zhu; Paula I Moreira
Insulin is a two-edged knife on the brain.
Journal of Alzheimer's disease : JAD 2009;18(3):483-507.
2009: V Prakash Reddy; Xiongwei Zhu; George Perry; Mark A. Smith
Oxidative stress in diabetes and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(4):763-74.
2009: Nikolaos Tezapsidis; Jane M Johnston; Mark A. Smith; J Wesson Ashford; Gemma Casadesus Smith; Nikolaos K Robakis; Benjamin Wolozin; George Perry; Xiongwei Zhu; Steven J Greco; Sraboni Sarkar
Leptin: a novel therapeutic strategy for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(4):731-40.
2009: Jeremy G Stone; Raj K Rolston; Masumi Ueda; Hyoung-gon Lee; Sandy L Richardson; Rudy J Castellani; George Perry; Mark A. Smith
Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.
International journal of clinical and experimental pathology 2009;2(3):267-74.
2008: Na-Hye Myung; Xiongwei Zhu; Inna I Kruman; Rudy J Castellani; Robert B Petersen; Sandra L Siedlak; George Perry; Mark A. Smith; Hyoung-gon Lee
Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes.
Age (Dordrecht, Netherlands) 2008;30(4):209-15.
2008: Merce Pallas; Antoni Camins; Mark A. Smith; George Perry; Hyoung-gon Lee; Gemma Casadesus Smith
From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).
Journal of Alzheimer's disease : JAD 2008;15(4):615-24.
2008: B Su; X Wang; A Nunomura; P I Moreira; H-gon Lee; George Perry; Mark A. Smith; Xiongwei Zhu
Oxidative stress signaling in Alzheimer's disease.
Current Alzheimer research 2008;5(6):525-32.
2008: Gjumrakch Aliev; Mark E Obrenovich; V Prakash Reddy; Justin Shenk; Paula I Moreira; Akihiko Nunomura; Xiongwei Zhu; Mark A. Smith; George Perry
Antioxidant therapy in Alzheimer's disease: theory and practice.
Mini reviews in medicinal chemistry 2008;8(13):1395-406.
2008: Michael W Marlatt; Paul J Lucassen; George Perry; Mark A. Smith; Xiongwei Zhu
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies.
Journal of Alzheimer's disease : JAD 2008;15(2):199-210.
2008: Luis F Gonzalez-Cuyar; George Perry; Hiroaki Miyajima; Craig S Atwood; Marcela Riveros-Angel; Patrick F Lyons; Sandra L Siedlak; Mark A. Smith; Rudy J Castellani
Redox active iron accumulation in aceruloplasminemia.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(5):466-71.
2008: Gjumrakch Aliev; Justin Shenk; Kathryn Fischbach; George Perry
Stem cell niches as clinical targets: the future of anti-ischemic therapy?
Nature clinical practice. Cardiovascular medicine 2008;5(9):590-1.
2008: Robert P Friedland; Johnathan M Tedesco; Andrea C Wilson; Craig S Atwood; Mark A. Smith; George Perry; Michael G Zagorski
Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies.
The Journal of biological chemistry 2008;283(33):22550-6.
2008: Rudy J Castellani; Akihiko Nunomura; Hyoung-gon Lee; George Perry; Mark A. Smith
Phosphorylated tau: toxic, protective, or none of the above.
Journal of Alzheimer's disease : JAD 2008;14(4):377-83.
2008: Katarzyna A Gustaw; Matthew R Garrett; Hyoung-gon Lee; Rudy J Castellani; Michael G Zagorski; Annamalai Prakasam; Sandra L Siedlak; Xiongwei Zhu; George Perry; Robert B Petersen; Robert P Friedland; Mark A. Smith
Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Journal of neurochemistry 2008;106(3):1350-6.
2008: Xiongwei Zhu; S L Siedlak; Yanming Wang; George Perry; Rudy J Castellani; M L Cohen; Mark A. Smith
Neuronal binucleation in Alzheimer disease hippocampus.
Neuropathology and applied neurobiology 2008;34(4):457-65.
2008: Joanna Collingwood; Ryan K K Chong; Takeshi Kasama; Lionel Cervera-Gontard; Rafal E Dunin-Borkowski; George Perry; Mihály Pósfai; Sandra L Siedlak; Edward T Simpson; Mark A. Smith; Jon Dobson
Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material.
Journal of Alzheimer's disease : JAD 2008;14(2):235-45.
2008: Rudy J Castellani; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A. Smith
Alzheimer disease pathology as a host response.
Journal of neuropathology and experimental neurology 2008;67(6):523-31.
2008: Bo Su; Xinglong Wang; Kelly L Drew; George Perry; Mark A. Smith; Xiongwei Zhu
Physiological regulation of tau phosphorylation during hibernation.
Journal of neurochemistry 2008;105(6):2098-108.
2008: Rudy J Castellani; Akihiko Nunomura; Raj K Rolston; Paula I Moreira; Atsushi Takeda; George Perry; Mark A. Smith
Sublethal RNA oxidation as a mechanism for neurodegenerative disease.
International journal of molecular sciences 2008;9(5):789-806.
2008: Paula I Moreira; Akihiko Nunomura; Masao Nakamura; Atsushi Takeda; Justin Shenk; Gjumrakch Aliev; Mark A. Smith; George Perry
Nucleic acid oxidation in Alzheimer disease.
Free radical biology & medicine 2008;44(8):1493-505.
2008: Reena S Shah; Hyoung-gon Lee; Zhu Xiongwei; George Perry; Mark A. Smith; Rudy J Castellani
Current approaches in the treatment of Alzheimer's disease.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(4):199-207.
2008: Siddhartha Mondragón-Rodríguez; Gustavo Basurto-Islas; Ismael Santa-Maria; Raúl Mena; Lester I Binder; Jesús Avila; Mark A. Smith; George Perry; Francisco García-Sierra
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
International journal of experimental pathology 2008;89(2):81-90.
2008: Paula I Moreira; Maria S Santos; Catarina R Oliveira; Justin Shenk; Akihiko Nunomura; Mark A. Smith; Xiongwei Zhu; George Perry
Alzheimer disease and the role of free radicals in the pathogenesis of the disease.
CNS & neurological disorders drug targets 2008;7(1):3-10.
2008: Daniel J Klionsky; Hagai Abeliovich; Patrizia Agostinis; Devendra K Agrawal; Gjumrakch Aliev; David S Askew; Misuzu Baba; Eric H Baehrecke; Ben A Bahr; Andrea Ballabio; Bruce A Bamber; Diane C Bassham; Ettore Bergamini; Xiaoning Bi; Martine Biard-Piechaczyk; Janice S Blum; Dale E Bredesen; Jeffrey L Brodsky; John H Brumell; Ulf T Brunk; Wilfried Bursch; Nadine Camougrand; Eduardo Cebollero; Francesco Cecconi; Yingyu Chen; Lih-Shen Chin; Augustine Choi; Charleen T Chu; Jongkyeong Chung; Peter G H Clarke; Robert S B Clark; Steven G Clarke; Corinne Clavé; John L Cleveland; Patrice Codogno; María I Colombo; Ana Coto-Montes; James M Cregg; Ana Maria Cuervo; Jayanta Debnath; Francesca Demarchi; Patrick B Dennis; Phillip A Dennis; Vojo Deretic; Rodney J Devenish; Federica Di Sano; J Fred Dice; Marian DiFiglia; Savithramma Dinesh-Kumar; Clark W Distelhorst; Mojgan Djavaheri-Mergny; Frank C Dorsey; Wulf Dröge; Michel Dron; William A Dunn; Michael Duszenko; N Tony Eissa; Zvulun Elazar; Audrey Esclatine; Eeva-Liisa Eskelinen; László Fésüs; Kim D Finley; Jose M. Fuentes; Juan Fueyo; Kozo Fujisaki; Brigitte Galliot; Fen-Biao Gao; David Gewirtz; Spencer B Gibson; Antje Gohla; Alfred L Goldberg; Ramon Gonzalez; Cristina González-Estévez; Sharon Gorski; Roberta Anne Gottlieb; Dieter Häussinger; You-Wen He; Kim Heidenreich; Joseph A Hill; Maria Høyer-Hansen; Xun Hu; Wei-Pang Huang; Akiko Iwasaki; Marja Jäättelä; William T Jackson; Xuejun Jiang; Shengkan Jin; Terje Johansen; Jae U. Jung; Motoni Kadowaki; Chanhee Kang; Ameeta Kelekar; David Kessel; Jan A K W Kiel; hong pyo kim; Adi Kimchi; Timothy J Kinsella; Kirill Kiselyov; Katsuhiko Kitamoto; Erwin Knecht; Masaaki Komatsu; Eiki Kominami; Seiji Kondo; Attila L Kovács; Guido Kroemer; Chia-Yi Kuan; Rakesh Kumar; Mondira Kundu; Jacques Landry; Marianne Laporte; Weidong Le; Huan-Yao Lei; Michael J Lenardo; Beth Levine; Andrew P Lieberman; Kah-Leong Lim; Fu-Cheng Lin; Willisa Liou; Leroy F Liu; Gabriel Lopez-Berestein; Carlos López-Otín; Bo Lu; Kay F Macleod; Walter Malorni; Wim Martinet; Ken Matsuoka; Josef Mautner; Alfred J Meijer; Alicia Meléndez; Paul Michels; Giovanni Miotto; wilhelm mistiaen; Noboru Mizushima; Baharia Mograbi; Iryna Monastyrska; Michael N Moore; Paula I Moreira; Yuji Moriyasu; Tomasz Motyl; Christian Münz; Leon O Murphy; Naweed I Naqvi; Thomas P Neufeld; Ichizo Nishino; Ralph A. Nixon; takeshi noda; Bernd Nürnberg; Michinaga Ogawa; Nancy L Oleinick; Laura J Olsen; Bulent Ozpolat; Shoshana Paglin; Glen E Palmer; Issidora Papassideri; Miles Parkes; David H Perlmutter; George Perry; Mauro Piacentini; Ronit Pinkas-Kramarski; Mark Prescott; Tassula Proikas-Cezanne; Nina Raben; Abdelhaq Rami; Fulvio Reggiori; Bärbel Rohrer; David C Rubinsztein; Kevin M Ryan; Junichi Sadoshima; Hiroshi Sakagami; Yasuyoshi Sakai; Marco Sandri; Chihiro Sasakawa; Miklós Sass; Claudio Schneider; Per O Seglen; Oleksandr Seleverstov; Jeffrey Settleman; John J Shacka; Irving M Shapiro; Andrei Sibirny; Elaine C M Silva-Zacarin; Hans-Uwe Simon; Cristiano Simone; Anne Simonsen; Mark A. Smith; Katharina Spanel-Borowski; Vickram Srinivas; Meredith Steeves; Harald Stenmark; Per E Stromhaug; Carlos S Subauste; Seiichiro Sugimoto; David Sulzer; Toshihiko Suzuki; Michele S Swanson; Ira Tabas; Fumihiko Takeshita; Nicholas J Talbot; Zsolt Tallóczy; Keiji Tanaka; Kozo Tanaka; Isei Tanida; Graham S Taylor; J. Paul Taylor; Alexei Terman; Gianluca Tettamanti; Craig Thompson; Michael Thumm; Aviva M Tolkovsky; Sharon A Tooze; Ray Truant; Lesya V Tumanovska; Yasuo Uchiyama; Takashi Ueno; Néstor L Uzcátegui; Ida van der Klei; Eva C Vaquero; Tibor Vellai; Michael W Vogel; Hong-Gang Wang; Paul Webster; John W Wiley; Zhijun Xi; Gutian Xiao; Joachim Yahalom; Jin-Ming Yang; George Yap; Xiao-Ming Yin; Tamotsu Yoshimori; Li Yu; Zhenyu Yue; Michisuke Yuzaki; Olga Zabirnyk; Xiaoxiang Zheng; Xiongwei Zhu; Russell L Deter
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Autophagy 2008;4(2):151-75.
2008: Elena Tamagno; Michela Guglielmotto; Manuela Aragno; Roberta Borghi; Riccardo Autelli; Luca Giliberto; Giuseppe Muraca; Oliviero Danni; Xiongwei Zhu; Mark A. Smith; George Perry; Dong-Gyu Jo; Mark P Mattson; Massimo Tabaton
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
Journal of neurochemistry 2008;104(3):683-95.
2008: S Mondragón-Rodríguez; Raúl Mena; Lester I Binder; Mark A. Smith; George Perry; Francisco García-Sierra
Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.
Neuropathology and applied neurobiology 2008;34(1):62-75.
2008: Hsien W Chan; Tianbing Liu; Giuseppe Verdile; Glenda Bishop; Ryan J Haasl; Mark A. Smith; George Perry; Ralph N Martins; Craig S Atwood
Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity.
International journal of clinical and experimental medicine 2008;1(1):76-88.
2008: Gjumrakch Aliev; Eldar Gasimov; Mark E Obrenovich; Kathryn Fischbach; Justin Shenk; Mark A. Smith; George Perry
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease.
Vascular health and risk management 2008;4(3):721-30.
2008: Kathryn J Bryan; Xiongwei Zhu; Peggy L R Harris; George Perry; Rudy J Castellani; Mark A. Smith; Gemma Casadesus Smith
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease.
Molecular neurodegeneration 2008;3():13.
2008: George Perry; Rudy J Castellani; Paula I Moreira; Hyoung-gon Lee; Xiongwei Zhu; Mark A. Smith
Pathology's new role: defining disease process and protective responses.
International journal of clinical and experimental pathology 2008;1(1):1-4.
2008: Akanksha Thakur; Sandra L Siedlak; Sheronica L James; David J Bonda; Akanksha Rao; Kate M Webber; Antoni Camins; Merce Pallas; Gemma Casadesus Smith; Hyoung-gon Lee; Robert Bowser; Arun K Raina; George Perry; Mark A. Smith; Xiongwei Zhu
Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.
International journal of clinical and experimental pathology 2008;1(2):134-46.
2008: Steven L Gelfand; Maximo Vento; Juan Sastre; W David Lust; Mark A. Smith; George Perry; Michele Walsh; Richard Martin
A new model of oxidative stress in rat pups.
Neonatology 2008;94(4):293-9.
2008: Gemma Casadesus Smith; Raj K Rolston; Kate M Webber; Craig S Atwood; Richard L Bowen; George Perry; Mark A. Smith
Menopause, estrogen, and gonadotropins in Alzheimer's disease.
Advances in clinical chemistry 2008;45():139-53.
2008: George Perry; Xiongwei Zhu; Asim K Babar; Sandra L Siedlak; Qiwei Yang; Genta Ito; Takeshi Iwatsubo; Mark A. Smith; Shu G Chen
Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies.
Neuro-degenerative diseases 2008;5(3-4):222-4.
2008: Lawrence M Sayre; George Perry; Mark A. Smith
Oxidative stress and neurotoxicity.
Chemical research in toxicology 2008;21(1):172-88.
2007: Xinglong Wang; Bo Su; George Perry; Mark A. Smith; Xiongwei Zhu
Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease.
Free radical biology & medicine 2007;43(12):1569-73.
2007: Kate M Webber; Gemma Casadesus Smith; Richard L Bowen; George Perry; Mark A. Smith
Evidence for the role of luteinizing hormone in Alzheimer disease.
Endocrine, metabolic & immune disorders drug targets 2007;7(4):300-3.
2007: Akihiko Nunomura; Paula I Moreira; Hyoung-gon Lee; Xiongwei Zhu; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases.
CNS & neurological disorders drug targets 2007;6(6):411-23.
2007: Rudy J Castellani; George Perry; Mark A. Smith
The role of novel chitin-like polysaccharides in Alzheimer disease.
Neurotoxicity research 2007;12(4):269-74.
2007: Takaaki Hayashi; Naomi Shishido; K Nakayama; Akihiko Nunomura; Mark A. Smith; George Perry; Masao Nakamura
Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide.
Free radical biology & medicine 2007;43(11):1552-9.
2007: Masao Nakamura; Naomi Shishido; Akihiko Nunomura; Mark A. Smith; George Perry; Y Hayashi; K Nakayama; T Hayashi
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron.
Biochemistry 2007;46(44):12737-43.
2007: Paula I Moreira; Sandra L Siedlak; Xinglong Wang; Maria S Santos; Catarina R Oliveira; Massimo Tabaton; Akihiko Nunomura; Luke I Szweda; Gjumrakch Aliev; Mark A. Smith; Xiongwei Zhu; George Perry
Increased autophagic degradation of mitochondria in Alzheimer disease.
Autophagy 2007;3(6):614-5.
2007: Kate M Webber; George Perry; Mark A. Smith; Gemma Casadesus Smith
The contribution of luteinizing hormone to Alzheimer disease pathogenesis.
Clinical medicine & research 2007;5(3):177-83.
2007: Quan Liu; Won-Kyu Ju; Jonathan G Crowston; Fang Xie; George Perry; Mark A. Smith; James D Lindsey; Robert N Weinreb
Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage.
Investigative ophthalmology & visual science 2007;48(10):4580-9.
2007: Rudy J Castellani; Paula I Moreira; Gang Liu; Jon Dobson; George Perry; Mark A. Smith; Xiongwei Zhu
Iron: the Redox-active center of oxidative stress in Alzheimer disease.
Neurochemical research 2007;32(10):1640-5.
2007: Paula I Moreira; Peggy L R Harris; Xiongwei Zhu; Maria S Santos; Catarina R Oliveira; Mark A. Smith; George Perry
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.
Journal of Alzheimer's disease : JAD 2007;12(2):195-206.
2007: Xiongwei Zhu; B Su; X Wang; Mark A. Smith; George Perry
Causes of oxidative stress in Alzheimer disease.
Cellular and molecular life sciences : CMLS 2007;64(17):2202-10.
2007: Xiongwei Zhu; Mark A. Smith; Kazuhiro Honda; Gjumrakch Aliev; Paula I Moreira; Akihiko Nunomura; Gemma Casadesus Smith; Peggy L R Harris; Sandra L Siedlak; George Perry
Vascular oxidative stress in Alzheimer disease.
Journal of the neurological sciences 2007;257(1-2):240-6.
2007: Paula I Moreira; Sandra L Siedlak; Xinglong Wang; Maria S Santos; Catarina R Oliveira; Massimo Tabaton; Akihiko Nunomura; Luke I Szweda; Gjumrakch Aliev; Mark A. Smith; Xiongwei Zhu; George Perry
Autophagocytosis of mitochondria is prominent in Alzheimer disease.
Journal of neuropathology and experimental neurology 2007;66(6):525-32.
2007: Akanksha Thakur; Xinglong Wang; Sandra L Siedlak; George Perry; Mark A. Smith; Xiongwei Zhu
c-Jun phosphorylation in Alzheimer disease.
Journal of neuroscience research 2007;85(8):1668-73.
2007: Hyoung-gon Lee; Xiongwei Zhu; Rudy J Castellani; Akihiko Nunomura; George Perry; Mark A. Smith
Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses.
The Journal of pharmacology and experimental therapeutics 2007;321(3):823-9.
2007: Robert B Petersen; Akihiko Nunomura; Hyoung-gon Lee; Gemma Casadesus Smith; George Perry; Mark A. Smith; Xiongwei Zhu
Signal transduction cascades associated with oxidative stress in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(2):143-52.
2007: Rudy J Castellani; Xiongwei Zhu; Hyoung-gon Lee; Paula I Moreira; George Perry; Mark A. Smith
Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
Expert review of neurotherapeutics 2007;7(5):473-85.
2007: Xiongwei Zhu; Jesús Avila; George Perry; Mark A. Smith
Treating the lesions, not the disease.
The American journal of pathology 2007;170(5):1457-9.
2007: Gemma Casadesus Smith; Erin L Milliken; Kate M Webber; Richard L Bowen; Zhenmin Lei; C V Rao; George Perry; Ruth A Keri; Mark A. Smith
Increases in luteinizing hormone are associated with declines in cognitive performance.
Molecular and cellular endocrinology 2007;269(1-2):107-11.
2007: Gemma Casadesus Smith; Paula I Moreira; Akihiko Nunomura; Sandra L Siedlak; William Bligh-Glover; Elizabeth Balraj; Grace J Petot; Mark A. Smith; George Perry
Indices of metabolic dysfunction and oxidative stress.
Neurochemical research 2007;32(4-5):717-22.
2007: Xiongwei Zhu; Hyoung-gon Lee; George Perry; Mark A. Smith
Alzheimer disease, the two-hit hypothesis: an update.
Biochimica et biophysica acta 2007;1772(4):494-502.
2007: Laura A Previll; Meredith Crosby; Rudy J Castellani; Robert Bowser; George Perry; Mark A. Smith; Xiongwei Zhu
Increased expression of p130 in Alzheimer disease.
Neurochemical research 2007;32(4-5):639-44.
2007: John K Wung; George Perry; Aaron Kowalski; Peggy L R Harris; Glenda M Bishop; Mehul A Trivedi; Sterling C Johnson; Mark A. Smith; David T Denhardt; Craig S Atwood
Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain.
Current Alzheimer research 2007;4(1):67-72.
2007: Quan Liu; Fang Xie; Raj Rolston; Paula I Moreira; Akihiko Nunomura; Xiongwei Zhu; Mark A. Smith; George Perry
Prevention and treatment of Alzheimer disease and aging: antioxidants.
Mini reviews in medicinal chemistry 2007;7(2):171-80.
2007: Kate M Webber; Gemma Casadesus Smith; Craig S Atwood; Richard L Bowen; George Perry; Mark A. Smith
Gonadotropins: a cohesive gender-based etiology of Alzheimer disease.
Molecular and cellular endocrinology 2007;260-262():271-5.
2007: Akihiko Nunomura; Paula I Moreira; Atsushi Takeda; Mark A. Smith; George Perry
Oxidative RNA damage and neurodegeneration.
Current medicinal chemistry 2007;14(28):2968-75.
2007: Glenda M Bishop; Mark A. Smith; Joseph C LaManna; Andrea C Wilson; George Perry; Craig S Atwood
Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia.
Redox report : communications in free radical research 2007;12(6):257-66.
2007: Luis F Gonzalez-Cuyar; Brian Hunter; Peggy L R Harris; George Perry; Mark A. Smith; Rudy J Castellani
Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress.
Redox report : communications in free radical research 2007;12(3):119-24.
2007: Teresa A Evans; Arun K Raina; André Delacourte; Olga Aprelikova; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A. Smith
BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease.
International journal of medical sciences 2007;4(3):140-5.
2007: Gemma Casadesus Smith; Mark A. Smith; Samar Basu; Jing Hua; Dae E Capobianco; Sandra L Siedlak; Xiongwei Zhu; George Perry
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease.
Molecular neurodegeneration 2007;2():2.
2006: Hyoung-gon Lee; Masumi Ueda; Yoichi Miyamoto; Yoshihiro Yoneda; George Perry; Mark A. Smith; Xiongwei Zhu
Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease.
Brain research 2006;1124(1):1-4.
2006: Hyoung-gon Lee; Masumi Ueda; Xiongwei Zhu; George Perry; Mark A. Smith
Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?
Journal of neuroscience research 2006;84(8):1856-61.
2006: Dora Lam-Himlin; Michael G Espey; George Perry; Mark A. Smith; Rudy J Castellani
Malignant glioma progression and nitric oxide.
Neurochemistry international 2006;49(8):764-8.
2006: Xiongwei Zhu; Sandra L Siedlak; Mark A. Smith; George Perry; Shu G Chen
LRRK2 protein is a component of Lewy bodies.
Annals of neurology 2006;60(5):617-8; author reply 618-9.
2006: Paola Strocchi; Mark A. Smith; George Perry; Elena Tamagno; Oliviero Danni; Andrea Pession; Alessia Gaiba; Barbara Dozza
Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells.
Neurobiology of aging 2006;27(11):1588-94.
2006: Gang Liu; Ping Men; Peggy L R Harris; Raj K Rolston; George Perry; Mark A. Smith
Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance.
Neuroscience letters 2006;406(3):189-93.
2006: Mark A. Smith; George Perry
Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Therapeutic strategies for Alzheimer's disease: the need for a new era of innovation.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(4):294-5.
2006: Xiongwei Zhu; Arun K Raina; George Perry; Mark A. Smith
Apoptosis in Alzheimer disease: a mathematical improbability.
Current Alzheimer research 2006;3(4):393-6.
2006: Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A. Smith
Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
The American journal of pathology 2006;169(3):738-9.
2006: Mark E Obrenovich; Mark A. Smith; Sandra L Siedlak; Shu G Chen; Jack C. de la Torre; George Perry; Gjumrakch Aliev
Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.
Neurotoxicity research 2006;10(1):43-56.
2006: Hyoung-gon Lee; George Perry; Xiongwei Zhu; Akihiko Nunomura; Mark A. Smith
Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression".
Free radical biology & medicine 2006;41(2):188-9.
2006: Sonia Franco; Maria A Blasco; Sandra L Siedlak; Peggy L R Harris; Paula I Moreira; George Perry; Mark A. Smith
Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy?
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(3):164-8.
2006: Diego Forero; Gemma Casadesus Smith; George Perry; Humberto Arboleda
Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms.
Journal of cellular and molecular medicine 2006;10(3):796-805.
2006: D Larry Sparks; Robert P Friedland; Suzana Petanceska; Bernard G Schreurs; Jiong Shi; George Perry; Mark A. Smith; A Sharma; S Derosa; Chuck Ziolkowski; G Stankovic
Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology.
The journal of nutrition, health & aging 2006;10(4):247-54.
2006: Xiongwei Zhu; George Perry; Paula I Moreira; Gjumrakch Aliev; Adam D Cash; Keisuke Hirai; Mark A. Smith
Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.
Journal of Alzheimer's disease : JAD 2006;9(2):147-53.
2006: Akihiko Nunomura; Rudy J Castellani; Xiongwei Zhu; Paula I Moreira; George Perry; Mark A. Smith
Involvement of oxidative stress in Alzheimer disease.
Journal of neuropathology and experimental neurology 2006;65(7):631-41.
2006: Hyoung-gon Lee; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A. Smith
Emerging evidence for the neuroprotective role of alpha-synuclein.
Experimental neurology 2006;200(1):1-7.
2006: Gjumrakch Aliev; Jonathan Miller; D W Leifer; Mark E Obrenovich; Justin Shenk; Mark A. Smith; Joseph C LaManna; George Perry; D W Lust; A R Cohen
Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system.
Journal of submicroscopic cytology and pathology 2006;38(2-3):85-91.
2006: Paula I Moreira; Xiongwei Zhu; Akihiko Nunomura; Mark A. Smith; George Perry
Therapeutic options in Alzheimer's disease.
Expert review of neurotherapeutics 2006;6(6):897-910.
2006: Rudy J Castellani; Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A. Smith
Neuropathology of Alzheimer disease: pathognomonic but not pathogenic.
Acta neuropathologica 2006;111(6):503-9.
2006: Paula I Moreira; Xiongwei Zhu; Hyoung-gon Lee; Kazuhiro Honda; Mark A. Smith; George Perry
The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease.
Mechanisms of ageing and development 2006;127(6):501-6.
2006: Akihiko Nunomura; Rudy J Castellani; Hyoung-gon Lee; Paula I Moreira; Xiongwei Zhu; George Perry; Mark A. Smith
Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.
Science of aging knowledge environment : SAGE KE 2006;2006(8):pe10.
2006: Takafumi Hasegawa; Michiko Matsuzaki-Kobayashi; Atsushi Takeda; Naoto Sugeno; Akio Kikuchi; Katsutoshi Furukawa; George Perry; Mark A. Smith; Yasuto Itoyama
Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease.
FEBS letters 2006;580(8):2147-52.
2006: Gemma Casadesus Smith; Kate M Webber; Craig S Atwood; Miguel Pappolla; George Perry; Richard L Bowen; Mark A. Smith
Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice.
Biochimica et biophysica acta 2006;1762(4):447-52.
2006: Mark A Smith; Xiongwei Zhu; Anne E Fortino; Peggy L R Harris; Hyoung-gon Lee; George Perry; Rudy J Castellani
Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy.
Age (Dordrecht, Netherlands) 2006;28(1):85-91.
2006: Rudy J Castellani; Hyoung-gon Lee; George Perry; Mark A. Smith
Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.
American journal of Alzheimer's disease and other dementias 2006;21(2):126-30.
2006: Xiongwei Zhu; Hyoung-gon Lee; Paula I Moreira; Mark A. Smith; George Perry
Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
Free radical biology & medicine 2006;40(5):737-9.
2006: Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A. Smith
Amyloid beta: the alternate hypothesis.
Current Alzheimer research 2006;3(1):75-80.
2006: Paula I Moreira; K Honda; Xiongwei Zhu; Akihiko Nunomura; Gemma Casadesus Smith; Mark A. Smith; George Perry
Brain and brawn: parallels in oxidative strength.
Neurology 2006;66(2 Suppl 1):S97-101.
2006: Xiongwei Zhu; Asim Babar; Sandra L Siedlak; Qiwei Yang; Genta Ito; Takeshi Iwatsubo; Mark A. Smith; George Perry; Shu G Chen
LRRK2 in Parkinson's disease and dementia with Lewy bodies.
Molecular neurodegeneration 2006;1():17.
2006: Akihiko Nunomura; Kazuhiro Honda; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Mark A. Smith; George Perry
Oxidative damage to RNA in neurodegenerative diseases.
Journal of biomedicine & biotechnology 2006;2006(3):82323.
2006: Mark A. Smith; George Perry; Xiongwei Zhu; Abdelali Haoudi
Neurodegenerative diseases: mechanisms and therapies.
Journal of biomedicine & biotechnology 2006;2006(3):47539.
2006: Gemma Casadesus Smith; Emma Ramiro Puig; Kate M Webber; Craig S Atwood; Margarida Castell Escuer; Richard L Bowen; George Perry; Mark A. Smith
Targeting gonadotropins: an alternative option for Alzheimer disease treatment.
Journal of biomedicine & biotechnology 2006;2006(3):39508.
2006: Barney E Dwyer; Meghan L Stone; Xiongwei Zhu; George Perry; Mark A. Smith
Heme deficiency in Alzheimer's disease: a possible connection to porphyria.
Journal of biomedicine & biotechnology 2006;2006(3):24038.
2006: Kate M Webber; Douglas M Stocco; Gemma Casadesus Smith; Richard L Bowen; Craig S Atwood; Laura A Previll; Peggy L R Harris; Xiongwei Zhu; George Perry; Mark A. Smith
Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease.
Molecular neurodegeneration 2006;1():14.
2006: George Perry
Solving the insoluble.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):301-4.
2006: Gemma Casadesus Smith; Matthew R Garrett; Kate M Webber; Anthony W Hartzler; Craig S Atwood; George Perry; Richard L Bowen; Mark A. Smith
The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease.
Drugs in R&D 2006;7(3):187-93.
2006: Paula I Moreira; Xiongwei Zhu; Quan Liu; Kazuhiro Honda; Sandra L Siedlak; Peggy L R Harris; Mark A. Smith; George Perry
Compensatory responses induced by oxidative stress in Alzheimer disease.
Biological research 2006;39(1):7-13.
2006: Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A. Smith
The fallacy of amyloid and cognition in Alzheimer's disease.
Drugs & aging 2006;23(2):179.
2006: Kate M Webber; Gemma Casadesus Smith; Xiongwei Zhu; Mark E Obrenovich; Craig S Atwood; George Perry; Richard L Bowen; Mark A. Smith
The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target.
Current pharmaceutical design 2006;12(6):691-7.
2005: Rudy J Castellani; Sandra L Siedlak; Anne E Fortino; George Perry; Bernardino Ghetti; Mark A. Smith
Chitin-like polysaccharides in Alzheimer's disease brains.
Current Alzheimer research 2005;2(4):419-23.
2005: Paula I Moreira; Kazuhiro Honda; Quan Liu; Maria S Santos; Catarina R Oliveira; Gjumrakch Aliev; Akihiko Nunomura; Xiongwei Zhu; Mark A. Smith; George Perry
Oxidative stress: the old enemy in Alzheimer's disease pathophysiology.
Current Alzheimer research 2005;2(4):403-8.
2005: Ismael Santa-María; Félix Hernández; Mark A. Smith; George Perry; Jesús Avila; Francisco J Moreno
Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers.
Molecular and cellular biochemistry 2005;278(1-2):203-12.
2005: Kate M Webber; Arun K Raina; Michael W Marlatt; Xiongwei Zhu; María I Prat; Laura Morelli; Gemma Casadesus Smith; George Perry; Mark A. Smith
The cell cycle in Alzheimer disease: a unique target for neuropharmacology.
Mechanisms of ageing and development 2005;126(10):1019-25.
2005: Gang Liu; Matthew R Garrett; Ping Men; Xiongwei Zhu; George Perry; Mark A. Smith
Nanoparticle and other metal chelation therapeutics in Alzheimer disease.
Biochimica et biophysica acta 2005;1741(3):246-52.
2005: Robert B Petersen; Sandra L Siedlak; Hyoung-gon Lee; Yong-Sun Kim; Akihiko Nunomura; Fabrizio Tagliavini; Bernardino Ghetti; Patrick Cras; Paula I Moreira; Rudy J Castellani; Marin Guentchev; Herbert Budka; James W Ironside; Pierluigi Gambetti; Mark A. Smith; George Perry
Redox metals and oxidative abnormalities in human prion diseases.
Acta neuropathologica 2005;110(3):232-8.
2005: Xiongwei Zhu; Paula I Moreira; Mark A. Smith; George Perry
Alzheimer's disease: an intracellular movement disorder?
Trends in molecular medicine 2005;11(9):391-3.
2005: De Lin; Hyoung-gon Lee; Quan Liu; George Perry; Mark A. Smith; Lawrence M Sayre
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.
Chemical research in toxicology 2005;18(8):1219-31.
2005: Gemma Casadesus Smith; Mark A. Smith; George Perry
Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2005;1(1):51-2.
2005: Barney E Dwyer; Atsushi Takeda; Xiongwei Zhu; George Perry; Mark A. Smith
Ferric cycle activity and Alzheimer disease.
Current neurovascular research 2005;2(3):261-7.
2005: Paula I Moreira; Sandra L Siedlak; Gjumrakch Aliev; Xiongwei Zhu; Adam D Cash; Mark A. Smith; George Perry
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(7):921-32.
2005: Xiongwei Zhu; Mark A. Smith; George Perry; Yang Wang; Austin P Ross; Huiwen W Zhao; Joseph C LaManna; Kelly L Drew
MAPKs are differentially modulated in arctic ground squirrels during hibernation.
Journal of neuroscience research 2005;80(6):862-8.
2005: Ismael Santa-María; Mark A. Smith; George Perry; Félix Hernández; Jesús Avila; Francisco J Moreno
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease.
Biochimica et biophysica acta 2005;1740(3):472-80.
2005: Kazuhiro Honda; Mark A. Smith; Xiongwei Zhu; Diane Baus; William C Merrick; Alan M Tartakoff; Thomas Hattier; Peggy L R Harris; Sandra L Siedlak; Hisashi Fujioka; Quan Liu; Paula I Moreira; Frank P Miller; Akihiko Nunomura; Shun Shimohama; George Perry
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron.
The Journal of biological chemistry 2005;280(22):20978-86.
2005: Xiongwei Zhu; Matthew Mei; Hyoung-gon Lee; Yang Wang; Jiahuai Han; George Perry; Mark A. Smith
P38 activation mediates amyloid-beta cytotoxicity.
Neurochemical research 2005;30(6-7):791-6.
2005: Paula I Moreira; Mark A. Smith; Xiongwei Zhu; Akihiko Nunomura; Rudy J Castellani; George Perry
Oxidative stress and neurodegeneration.
Annals of the New York Academy of Sciences 2005;1043():545-52.
2005: Kate M Webber; Gemma Casadesus Smith; Michael W Marlatt; George Perry; Clive R Hamlin; Craig S Atwood; Richard L Bowen; Mark A. Smith
Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis.
Annals of the New York Academy of Sciences 2005;1052():201-9.
2005: J Wesson Ashford; Craig S Atwood; John P Blass; Richard L Bowen; Caleb E Finch; Khalid Iqbal; James A Joseph; George Perry
What is aging? What is its role in Alzheimer's disease? What can we do about it?
Journal of Alzheimer's disease : JAD 2005;7(3):247-53; discussion 255-62.
2005: Hyoung-gon Lee; Rudy J Castellani; Xiongwei Zhu; George Perry; Mark A. Smith
Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?
International journal of experimental pathology 2005;86(3):133-8.
2005: Luis Barbeito; Jerold Chun; Lester I Binder; Vivaldo Moura Neto; George Perry; Claudio Scazzochio; Galileo Violini
The end of a Chilean institute.
Science (New York, N.Y.) 2005;308(5723):792-3.
2005: V Prakash Reddy; Matthew R Garrett; George Perry; Mark A. Smith
Carnosine: a versatile antioxidant and antiglycating agent.
Science of aging knowledge environment : SAGE KE 2005;2005(18):pe12.
2005: Mark A. Smith; Akihiko Nunomura; Hyoung-gon Lee; Xiongwei Zhu; Paula I Moreira; Jesús Avila; George Perry
Chronological primacy of oxidative stress in Alzheimer disease.
Neurobiology of aging 2005;26(5):579-80.
2005: Paula I Moreira; Catarina R Oliveira; Maria S Santos; Akihiko Nunomura; Kazuhiro Honda; Xiongwei Zhu; Mark A. Smith; George Perry
A second look into the oxidant mechanisms in Alzheimer's disease.
Current neurovascular research 2005;2(2):179-84.
2005: Kate M Webber; Gemma Casadesus Smith; George Perry; Craig S Atwood; Richard Bowen; Mark A. Smith
Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis.
Alzheimer disease and associated disorders 2005;19(2):95-9.
2005: Hyoung-gon Lee; George Perry; Paula I Moreira; Matthew R Garrett; Quan Liu; Xiongwei Zhu; Atsushi Takeda; Akihiko Nunomura; Mark A. Smith
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
Trends in molecular medicine 2005;11(4):164-9.
2005: Ali Aliyev; Shu G Chen; Dilara Seyidova; Mark A. Smith; George Perry; Jack C. de la Torre; Gjumrakch Aliev
Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease.
Journal of the neurological sciences 2005;229-230():285-92.
2005: Quan Liu; Mark A. Smith; Jesús Avila; John DeBernardis; Mayank M Kansal; Atsushi Takeda; Xiongwei Zhu; Akihiko Nunomura; Kazuhiro Honda; Paula I Moreira; Catarina R Oliveira; Maria S Santos; Shun Shimohama; Gjumrakch Aliev; Jack C. de la Torre; Hossein A Ghanbari; Sandra L Siedlak; Peggy L R Harris; Lawrence M Sayre; George Perry
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Free radical biology & medicine 2005;38(6):746-54.
2005: Kate M Webber; Mark A. Smith; Hyoung-gon Lee; Peggy L R Harris; Paula I Moreira; George Perry; Xiongwei Zhu
Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
Journal of neuroscience research 2005;79(4):554-60.
2005: Xiongwei Zhu; George Perry; Mark A. Smith
Insulin signaling, diabetes mellitus and risk of Alzheimer disease.
Journal of Alzheimer's disease : JAD 2005;7(1):81-4.
2005: Gemma Casadesus Smith; Craig S Atwood; Xiongwei Zhu; Anthony W Hartzler; Kate M Webber; George Perry; Richard L Bowen; Mark A. Smith
Evidence for the role of gonadotropin hormones in the development of Alzheimer disease.
Cellular and molecular life sciences : CMLS 2005;62(3):293-8.
2005: Elena Tamagno; Maurizio Parola; Paola Bardini; Alessandra Piccini; Roberta Borghi; Michela Guglielmotto; Gianni Santoro; Annalisa Davit; Oliviero Danni; Mark A. Smith; George Perry; Massimo Tabaton
Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.
Journal of neurochemistry 2005;92(3):628-36.
2005: Jue Yuan; Michael Kinter; John McGeehan; George Perry; Geoff Kneale; Pierluigi Gambetti; Wen-Quan Zou
Concealment of epitope by reduction and alkylation in prion protein.
Biochemical and biophysical research communications 2005;326(3):652-9.
2005: Quan Liu; Hyoung-gon Lee; Kazuhiro Honda; Sandra L Siedlak; Peggy L R Harris; Adam D Cash; Xiongwei Zhu; Jesús Avila; Akihiko Nunomura; Atsushi Takeda; Mark A. Smith; George Perry
Tau modifiers as therapeutic targets for Alzheimer's disease.
Biochimica et biophysica acta 2005;1739(2-3):211-5.
2005: Lawrence M Sayre; Paula I Moreira; Mark A. Smith; George Perry
Metal ions and oxidative protein modification in neurological disease.
Annali dell'Istituto superiore di sanità 2005;41(2):143-64.
2005: Xiongwei Zhu; Hyoung-gon Lee; Gemma Casadesus Smith; Jesús Avila; Kelly L Drew; George Perry; Mark A. Smith
Oxidative imbalance in Alzheimer's disease.
Molecular neurobiology 2005;31(1-3):205-17.
2005: M Sahin; Sibel Berker Karauzum; George Perry; Mark A. Smith; Yakup Aliciguzel
Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration.
Neurotoxicity research 2005;7(3):243-50.
2005: Michael W Marlatt; Kate M Webber; Paula I Moreira; Hyoung-gon Lee; Gemma Casadesus Smith; Kazuhiro Honda; Xiongwei Zhu; George Perry; Mark A. Smith
Therapeutic opportunities in Alzheimer disease: one for all or all for one?
Current medicinal chemistry 2005;12(10):1137-47.
2005: Paula I Moreira; Mark A. Smith; Xiongwei Zhu; Kazuhiro Honda; Hyoung-gon Lee; Gjumrakch Aliev; George Perry
Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?
Drug news & perspectives 2005;18(1):13-9.
2004: Quan Liu; F Xie; Sandra L Siedlak; Akihiko Nunomura; K Honda; Paula I Moreira; X Zhua; Mark A. Smith; George Perry
Neurofilament proteins in neurodegenerative diseases.
Cellular and molecular life sciences : CMLS 2004;61(24):3057-75.
2004: Paula I Moreira; Mark A. Smith; Xiongwei Zhu; Maria S Santos; Catarina R Oliveira; George Perry
Therapeutic potential of oxidant mechanisms in Alzheimer's disease.
Expert review of neurotherapeutics 2004;4(6):995-1004.
2004: Xiongwei Zhu; Mark A. Smith; George Perry; Gjumrakch Aliev
Mitochondrial failures in Alzheimer's disease.
American journal of Alzheimer's disease and other dementias 2004;19(6):345-52.
2004: Hyoung-gon Lee; Paula I Moreira; Xiongwei Zhu; Mark A. Smith; George Perry
Staying connected: synapses in Alzheimer disease.
The American journal of pathology 2004;165(5):1461-4.
2004: Jack C. de la Torre; Gjumrakch Aliev; George Perry
Drug therapy in Alzheimer's disease.
The New England journal of medicine 2004;351(18):1911-3; author reply 1911-3.
2004: Akihiko Nunomura; Shigeru Chiba; Carol F Lippa; Patrick Cras; Rajesh N. Kalaria; Atsushi Takeda; Kazuhiro Honda; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.
Neurobiology of disease 2004;17(1):108-13.
2004: Atsushi Takeda; Yasuto Itoyama; Teiko Kimpara; Xiongwei Zhu; Jesús Avila; Barney E Dwyer; George Perry; Mark A. Smith
Heme catabolism and heme oxygenase in neurodegenerative disease.
Antioxidants & redox signaling 2004;6(5):888-94.
2004: Gjumrakch Aliev; Mark A. Smith; Jack C. de la Torre; George Perry
Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease.
Mitochondrion 2004;4(5-6):649-63.
2004: Gemma Casadesus Smith; Xiongwei Zhu; Craig S Atwood; Kate M Webber; George Perry; Richard L Bowen; Mark A. Smith
Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease.
Current drug targets. CNS and neurological disorders 2004;3(4):281-5.
2004: Xiongwei Zhu; Kate M Webber; Gemma Casadesus Smith; Arun K Raina; Hyoung-gon Lee; Michael W Marlatt; Anthony W Hartzler; Craig S Atwood; George Perry; Mark A. Smith
Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities.
Current drug targets 2004;5(6):559-63.
2004: Takafumi Hasegawa; Michiko Matsuzaki; Atsushi Takeda; Akio Kikuchi; Hirotoshi Akita; George Perry; Mark A. Smith; Yasuto Itoyama
Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells.
Brain research 2004;1013(1):51-9.
2004: Gjumrakch Aliev; Rudy J Castellani; Robert B Petersen; G Burnstock; George Perry; Mark A. Smith
Pathobiology of familial hypercholesterolemic atherosclerosis.
Journal of submicroscopic cytology and pathology 2004;36(3-4):225-40.
2004: Ali Aliyev; Dilara Seyidova; Nizami Rzayev; Mark E Obrenovich; Bruce Lamb; Shu G Chen; Mark A. Smith; George Perry; Jack C. de la Torre; Gjumrakch Aliev
Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?
Neurological research 2004;26(5):547-53.
2004: Rudy J Castellani; Kazuhiro Honda; Xiongwei Zhu; Adam D Cash; Akihiko Nunomura; George Perry; Mark A. Smith
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease.
Ageing research reviews 2004;3(3):319-26.
2004: Lawrence M Sayre; Peggy L R Harris; George Perry; Mark A Smith
In situ localization of nonenzymatic peroxidase-like activity of tissue-bound transition metals.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2004;Chapter 17():Unit17.4.
2004: Hyoung-gon Lee; Gemma Casadesus Smith; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A. Smith
Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease.
Annals of the New York Academy of Sciences 2004;1019():1-4.
2004: Xiongwei Zhu; Yang Wang; Osamu Ogawa; Hyoung-gon Lee; Arun K Raina; Sandra L Siedlak; Peggy L R Harris; Hisashi Fujioka; Shun Shimohama; Massimo Tabaton; Craig S Atwood; Robert B Petersen; George Perry; Mark A. Smith
Neuroprotective properties of Bcl-w in Alzheimer disease.
Journal of neurochemistry 2004;89(5):1233-40.
2004: Barbara Dozza; Mark A. Smith; George Perry; Massimo Tabaton; Paola Strocchi
Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells.
Journal of neurochemistry 2004;89(5):1224-32.
2004: Barney E Dwyer; Arun K Raina; George Perry; Mark A. Smith
Homocysteine and Alzheimer's disease: a modifiable risk?
Free radical biology & medicine 2004;36(11):1471-5.
2004: Richard L Bowen; Giuseppe Verdile; Tianbing Liu; Albert F Parlow; George Perry; Mark A. Smith; Ralph N Martins; Craig S Atwood
Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
The Journal of biological chemistry 2004;279(19):20539-45.
2004: Jesús Avila; Mar Pérez; José J Lucas; Alberto Gómez-Ramos; Ismael Santa-María; Francisco Moreno; Mark A. Smith; George Perry; Félix Hernández
Assembly in vitro of tau protein and its implications in Alzheimer's disease.
Current Alzheimer research 2004;1(2):97-101.
2004: Dilara Seyidova; Ali Aliyev; Nizami Rzayev; Mark E Obrenovich; Bruce Lamb; Mark A. Smith; Jack C. de la Torre; George Perry; Gjumrakch Aliev
The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease.
In vivo (Athens, Greece) 2004;18(3):325-33.
2004: Rudy J Castellani; Mark A. Smith; George Perry; Robert P Friedland
Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis.
Neurobiology of aging 2004;25(5):599-602; discussion 603-4.
2004: Shin-Chung Kang; David Brown; Matthew Whiteman; Ruliang Li; Tao Pan; George Perry; Thomas Wisniewski; Man-Sun Sy; Boon-Seng Wong
Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice.
The Journal of pathology 2004;203(1):603-8.
2004: Gemma Casadesus Smith; Mark A. Smith; Xiongwei Zhu; Gjumrakch Aliev; Adam D Cash; Kazuhiro Honda; Robert B Petersen; George Perry
Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species.
Journal of Alzheimer's disease : JAD 2004;6(2):165-9.
2004: Hyoung-gon Lee; Gemma Casadesus Smith; Xiongwei Zhu; James A Joseph; George Perry; Mark A. Smith
Perspectives on the amyloid-beta cascade hypothesis.
Journal of Alzheimer's disease : JAD 2004;6(2):137-45.
2004: Xiongwei Zhu; Arun K Raina; George Perry; Mark A. Smith
Alzheimer's disease: the two-hit hypothesis.
Lancet neurology 2004;3(4):219-26.
2004: Hyoung-gon Lee; Osamu Ogawa; Xiongwei Zhu; Michael J O'Neill; Robert B Petersen; Rudy J Castellani; Hossein A Ghanbari; George Perry; Mark A. Smith
Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease.
Acta neuropathologica 2004;107(4):365-71.
2004: Xiongwei Zhu; Arun K Raina; Hyoung-gon Lee; Gemma Casadesus Smith; Mark A. Smith; George Perry
Oxidative stress signalling in Alzheimer's disease.
Brain research 2004;1000(1-2):32-9.
2004: Kazuhiro Honda; Gemma Casadesus Smith; Robert B Petersen; George Perry; Mark A. Smith
Oxidative stress and redox-active iron in Alzheimer's disease.
Annals of the New York Academy of Sciences 2004;1012():179-82.
2004: Xiongwei Zhu; Andy McShea; Peggy L R Harris; Arun K Raina; Rudy J Castellani; Jens Oliver Funk; Sapan Shah; Craig S Atwood; Richard Bowen; Robert Bowser; Laura Morelli; George Perry; Mark A. Smith
Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.
Journal of neuroscience research 2004;75(5):698-703.
2004: Hossein A Ghanbari; Kasra Ghanbari; Peggy L R Harris; Paul K Jones; Zvezdana Kubat; Rudy J Castellani; Benjamin Wolozin; Mark A. Smith; George Perry
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients.
Aging cell 2004;3(1):41-4.
2004: Tianbing Liu; George Perry; Hsien W Chan; Giuseppe Verdile; Ralph N Martins; Mark A. Smith; Craig S Atwood
Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.
Journal of neurochemistry 2004;88(3):554-63.
2004: Craig S Atwood; George Perry; Hong Zeng; Yoji Kato; Walton D Jones; Ke-Qing Ling; Xudong Huang; Robert D. Moir; Dandan Wang; Lawrence M Sayre; Mark A. Smith; Shu G Chen; Ashley I Bush
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.
Biochemistry 2004;43(2):560-8.
2004: Kate M Webber; Richard Bowen; Gemma Casadesus Smith; George Perry; Craig S Atwood; Mark A. Smith
Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection.
Acta neurobiologiae experimentalis 2004;64(1):113-8.
2004: Hyoung-gon Lee; Xiongwei Zhu; Michael J O'Neill; Kate M Webber; Gemma Casadesus Smith; Michael W Marlatt; Arun K Raina; George Perry; Mark A. Smith
The role of metabotropic glutamate receptors in Alzheimer's disease.
Acta neurobiologiae experimentalis 2004;64(1):89-98.
2004: Michael W Marlatt; Hyoung-gon Lee; George Perry; Mark A. Smith; Xiongwei Zhu
Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease.
Acta neurobiologiae experimentalis 2004;64(1):81-7.
2004: Alberto Gómez-Ramos; Mark A. Smith; George Perry; Jesús Avila
Tau phosphorylation and assembly.
Acta neurobiologiae experimentalis 2004;64(1):33-9.
2004: Rudy J Castellani; George Perry; Mark A. Smith
Prion disease and Alzheimer's disease: pathogenic overlap.
Acta neurobiologiae experimentalis 2004;64(1):11-7.
2003: George Perry; Rudy J Castellani; Mark A. Smith; Peggy L R Harris; Zvezdana Kubat; Kasra Ghanbari; Paul K Jones; Giovanni Cordone; Massimo Tabaton; Benjamin Wolozin; Hossein A Ghanbari
Oxidative damage in the olfactory system in Alzheimer's disease.
Acta neuropathologica 2003;106(6):552-6.
2003: Hyoung-gon Lee; Robert B Petersen; Xiongwei Zhu; Kazuhiro Honda; Gjumrakch Aliev; Mark A. Smith; George Perry
Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?
Brain pathology (Zurich, Switzerland) 2003;13(4):630-8.
2003: Xiongwei Zhu; Arun K Raina; Hyoung-gon Lee; Mark Chao; Akihiko Nunomura; Massimo Tabaton; Robert B Petersen; George Perry; Mark A. Smith
Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways.
Antioxidants & redox signaling 2003;5(5):571-6.
2003: George Perry; Akihiko Nunomura; Arun K Raina; Gjumrakch Aliev; Sandra L Siedlak; Peggy L R Harris; Gemma Casadesus Smith; Robert B Petersen; William Bligh-Glover; Elizabeth Balraj; Grace J Petot; Mark A. Smith
A metabolic basis for Alzheimer disease.
Neurochemical research 2003;28(10):1549-52.
2003: Gjumrakch Aliev; Dilara Seyidova; Bruce Lamb; Mark E Obrenovich; Sandra L Siedlak; Harry V Vinters; Robert P Friedland; Joseph C LaManna; Mark A. Smith; George Perry
Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
Neurological research 2003;25(6):665-74.
2003: Craig S Atwood; Richard L Bowen; Mark A. Smith; George Perry
Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply.
Brain research. Brain research reviews 2003;43(1):164-78.
2003: Craig S Atwood; Mark E Obrenovich; Tianbing Liu; Hsien Chan; George Perry; Mark A. Smith; Ralph N Martins
Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta.
Brain research. Brain research reviews 2003;43(1):1-16.
2003: Yoshihisa Kitamura; Daiju Tsuchiya; Kazuyuki Takata; Keiichi Shibagaki; Takashi Taniguchi; Mark A. Smith; George Perry; Hiroaki Miki; Tadaomi Takenawa; Shun Shimohama
Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease.
Neuroscience letters 2003;346(3):149-52.
2003: Quan Liu; Arun K Raina; Mark A. Smith; Lawrence M Sayre; George Perry
Hydroxynonenal, toxic carbonyls, and Alzheimer disease.
Molecular aspects of medicine 2003;24(4-5):305-13.
2003: Gjumrakch Aliev; Mark E Obrenovich; Dilara Seyidova; Nizami Rzayev; Ali Aliyev; Arun K Raina; Joseph C LaManna; Mark A. Smith; George Perry
X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment.
Journal of submicroscopic cytology and pathology 2003;35(3):253-66.
2003: Xiongwei Zhu; Zheng Sun; Hyoung-gon Lee; Sandra L Siedlak; George Perry; Mark A. Smith
Distribution, levels, and activation of MEK1 in Alzheimer's disease.
Journal of neurochemistry 2003;86(1):136-42.
2003: Nicole R Bianco; George Perry; Mark A. Smith; Dennis J Templeton; Monica M Montano
Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1344-55.
2003: Etsuro Matsubara; Tara Bryant-Thomas; Javier Pacheco Quinto; Tracey L Henry; Burkhard Poeggeler; Donald Herbert; Felix Cruz-Sanchez; Yau-Jan Chyan; Mark A. Smith; George Perry; Mikio Shoji; Koji Abe; Anna Leone; Inge Grundke-Ikbal; Glenn L Wilson; Jorge Ghiso; Christina Williams; Lorenzo M Refolo; Miguel Pappolla; Daniel G Chain; Eyal Neria
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
Journal of neurochemistry 2003;85(5):1101-8.
2003: Maki Tateyama; Atsushi Takeda; Yoshiaki Onodera; M Matsuzaki; Takafumi Hasegawa; Akihiko Nunomura; K Hirai; George Perry; Mark A. Smith; Yasuto Itoyama
Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.
Acta neuropathologica 2003;105(6):581-5.
2003: Shane R Bruckner; George Perry; Steven Estus
4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis.
Journal of neurochemistry 2003;85(4):999-1005.
2003: Adam D Cash; Gjumrakch Aliev; Sandra L Siedlak; Akihiko Nunomura; Hisashi Fujioka; Xiongwei Zhu; Arun K Raina; Harry V Vinters; Massimo Tabaton; Anne B Johnson; Manuel M Paula-Barbosa; Jesus Avíla; Paul K Jones; Rudy J Castellani; Mark A. Smith; George Perry
Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.
The American journal of pathology 2003;162(5):1623-7.
2003: Osamu Ogawa; Xiongwei Zhu; Hyoung-gon Lee; Arun K Raina; Mark E Obrenovich; Robert Bowser; Hossein A Ghanbari; Rudy J Castellani; George Perry; Mark A. Smith
Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
Acta neuropathologica 2003;105(5):524-8.
2003: Gerald Veurink; Dan Liu; Kevin Taddei; George Perry; Mark A. Smith; Terry A Robertson; Eugene Hone; David M Groth; Craig S Atwood; Ralph N Martins
Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants.
Free radical biology & medicine 2003;34(8):1070-7.
2003: Osamu Ogawa; Hyoung-gon Lee; Xiongwei Zhu; Arun K Raina; Peggy L R Harris; Rudy J Castellani; George Perry; Mark A. Smith
Increased p27, an essential component of cell cycle control, in Alzheimer's disease.
Aging cell 2003;2(2):105-10.
2003: Arun K Raina; Ayala Hochman; Harold Ickes; Xiongwei Zhu; Osamu Ogawa; Adam D Cash; Shun Shimohama; George Perry; Mark A. Smith
Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(2):251-4.
2003: Xiongwei Zhu; Osamu Ogawa; Yang Wang; George Perry; Mark A. Smith
JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.
Journal of neurochemistry 2003;85(1):87-93.
2003: Jian Dong; Craig S Atwood; Vernon E Anderson; Sandra L Siedlak; Mark A. Smith; George Perry; Paul R Carey
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Biochemistry 2003;42(10):2768-73.
2003: Alberto Gómez-Ramos; JAVIER DIAZ-NIDO; Mark A. Smith; George Perry; Jesús Avila
Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells.
Journal of neuroscience research 2003;71(6):863-70.
2003: Mark A. Smith; George Perry; Craig S Atwood; Richard L Bowen
Estrogen replacement and risk of Alzheimer disease.
JAMA : the journal of the American Medical Association 2003;289(9):1100; author reply 1101-2.
2003: George Perry; Marta A Taddeo; Robert B Petersen; Rudy J Castellani; Peggy L R Harris; Sandra L Siedlak; Adam D Cash; Quan Liu; Akihiko Nunomura; Craig S Atwood; Mark A. Smith
Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(1):77-81.
2003: Craig S Atwood; George Perry; Mark A. Smith
Cerebral hemorrhage and amyloid-beta.
Science (New York, N.Y.) 2003;299(5609):1014; author reply 1014.
2003: Kazuyuki Takata; Yoshihisa Kitamura; Jun-ichi Kakimura; Keiichi Shibagaki; Daiju Tsuchiya; Takashi Taniguchi; Mark A. Smith; George Perry; Shun Shimohama
Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis.
Biochemical and biophysical research communications 2003;301(3):699-703.
2003: Arun K Raina; Xiongwei Zhu; Shun Shimohama; George Perry; Mark A. Smith
Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept.
Cell biochemistry and biophysics 2003;39(3):249-55.
2003: Gjumrakch Aliev; Mark A. Smith; Mark E Obrenovich; Jack C. de la Torre; George Perry
Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease.
Neurotoxicity research 2003;5(7):491-504.
2003: Xiongwei Zhu; George Perry; Mark A. Smith
Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway.
Redox report : communications in free radical research 2003;8(3):129-33.
2002: George Perry; Marta A Taddeo; Akihiko Nunomura; Xiongwei Zhu; Tania Zenteno-Savin; Kelly L Drew; Shun Shimohama; Jesús Avila; Rudy J Castellani; Mark A. Smith
Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):507-13.
2002: Kelly L Drew; Ø Tøien; Patricia M Rivera; Mark A. Smith; George Perry; Margaret E Rice
Role of the antioxidant ascorbate in hibernation and warming from hibernation.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):483-92.
2002: George Perry; Akihiko Nunomura; Keisuke Hirai; Xiongwei Zhu; Mar Pérez; Jesús Avila; Rudy J Castellani; Craig S Atwood; Gjumrakch Aliev; Lawrence M Sayre; Atsushi Takeda; Mark A. Smith
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
Free radical biology & medicine 2002;33(11):1475-9.
2002: Akihiko Nunomura; Shigeru Chiba; Kenji Kosaka; Atsushi Takeda; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
Neuroreport 2002;13(16):2035-9.
2002: Kazuyuki Takata; Yoshihisa Kitamura; Jun-ichi Kakimura; Keiichi Shibagaki; Tadatsugu Taniguchi; Peter J Gebicke-Haerter; Mark A. Smith; George Perry; Shun Shimohama
Possible protective mechanisms of heme oxygenase-1 in the brain.
Annals of the New York Academy of Sciences 2002;977():501-6.
2002: Jun-ichi Kakimura; Yoshihisa Kitamura; Kazuyuki Takata; Daiju Tsuchiya; Tadatsugu Taniguchi; Peter J Gebicke-Haerter; Mark A. Smith; George Perry; Shun Shimohama
Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits.
Annals of the New York Academy of Sciences 2002;977():327-32.
2002: Gjumrakch Aliev; Dilara Seyidova; Maxwell Neal; Jiong Shi; Bruce Lamb; Sandra L Siedlak; Harry V Vinters; Elizabeth Head; George Perry; Joseph C LaManna; Robert P Friedland; Carl W Cotman
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
Annals of the New York Academy of Sciences 2002;977():45-64.
2002: Mark E Obrenovich; James A Joseph; Craig S Atwood; George Perry; Mark A. Smith
Amyloid-beta: a (life) preserver for the brain.
Neurobiology of aging 2002;23(6):1097-9.
2002: Mark A. Smith; Gemma Casadesus Smith; James A Joseph; George Perry
Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain.
Free radical biology & medicine 2002;33(9):1194-9.
2002: Richard L Bowen; Mark A. Smith; Peggy L R Harris; Zvezdana Kubat; Ralph N Martins; Rudy J Castellani; George Perry; Craig S Atwood
Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
Journal of neuroscience research 2002;70(3):514-8.
2002: Rudy J Castellani; Keisuke Hirai; Gjumrakch Aliev; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Adam D Cash; Mark E Obrenovich; George Perry; Mark A. Smith
Role of mitochondrial dysfunction in Alzheimer's disease.
Journal of neuroscience research 2002;70(3):357-60.
2002: Craig S Atwood; Glenda M Bishop; George Perry; Mark A. Smith
Amyloid-beta: a vascular sealant that protects against hemorrhage?
Journal of neuroscience research 2002;70(3):356.
2002: Osamu Ogawa; Xiongwei Zhu; George Perry; Mark A. Smith
Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease.
Science of aging knowledge environment : SAGE KE 2002;2002(41):pe16.
2002: Adam D Cash; George Perry; Osamu Ogawa; Arun K Raina; Xiongwei Zhu; Mark A. Smith
Is Alzheimer's disease a mitochondrial disorder?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2002;8(5):489-96.
2002: Hyoung-gon Lee; Xiongwei Zhu; Hossein A Ghanbari; Osamu Ogawa; Arun K Raina; Micheal J O'Neill; George Perry; Mark A. Smith
Differential regulation of glutamate receptors in Alzheimer's disease.
Neuro-Signals 2002;11(5):282-92.
2002: Xiongwei Zhu; Hyoung-gon Lee; Arun K Raina; George Perry; Mark A. Smith
The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
Neuro-Signals 2002;11(5):270-81.
2002: Anthony W Hartzler; Xiongwei Zhu; Sandra L Siedlak; Rudy J Castellani; Jesús Avila; George Perry; Mark A. Smith
The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.
Neurobiology of aging 2002;23(5):855-9.
2002: Adam D Cash; George Perry; Mark A. Smith
Therapeutic potential in Alzheimer disease.
Current medicinal chemistry 2002;9(17):1605-10.
2002: Elena Tamagno; Paola Bardini; Alessandra Obbili; Antonella Vitali; Roberta Borghi; Damiano Zaccheo; MARIA ADELAIDE PRONZATO; Oliviero Danni; Mark A. Smith; George Perry; Massimo Tabaton
Oxidative stress increases expression and activity of BACE in NT2 neurons.
Neurobiology of disease 2002;10(3):279-88.
2002: Jiong Shi; George Perry; Marc S Berridge; Gjumrakch Aliev; Sandra L Siedlak; Mark A. Smith; Joseph C LaManna; Robert P Friedland
Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(8):1044-51.
2002: Mark A. Smith; Craig S Atwood; James A Joseph; George Perry
Ill-fated amyloid-beta vaccine.
Journal of neuroscience research 2002;69(3):285.
2002: Miguel Pappolla; Mark A. Smith; Tara Bryant-Thomas; Nicolas Bazan; Suzana Petanceska; George Perry; Leon J Thal; Mary Sano; Lorenzo M Refolo
Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis.
Free radical biology & medicine 2002;33(2):173-81.
2002: Craig S Atwood; Ralph N Martins; Mark A. Smith; George Perry
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins.
Peptides 2002;23(7):1343-50.
2002: Catherine A Rottkamp; Craig S Atwood; James A Joseph; Akihiko Nunomura; George Perry; Mark A. Smith
The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease.
Peptides 2002;23(7):1333-41.
2002: Mark A. Smith; James A Joseph; Craig S Atwood; George Perry
Dangers of the amyloid-beta vaccination.
Acta neuropathologica 2002;104(1):110.
2002: Mark A. Smith; George Perry; William A Pryor
Causes and consequences of oxidative stress in Alzheimer's disease.
Free radical biology & medicine 2002;32(11):1049.
2002: Mark A. Smith; Craig S Atwood; James A Joseph; George Perry
Predicting the failure of amyloid-beta vaccine.
Lancet 2002;359(9320):1864-5.
2002: Mark A. Smith; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Craig S Atwood; Arun K Raina; Catherine A Rottkamp; Lawrence M Sayre; Robert P Friedland; George Perry
Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
Neurochemistry international 2002;40(6):527-31.
2002: Glenda M Bishop; Stephen R Robinson; Mark A. Smith; George Perry; Craig S Atwood
Call for Elan to publish Alzheimer's trial details.
Nature 2002;416(6882):677.
2002: Miguel Pappolla; Marcia J Simovich; Tara Bryant-Thomas; Yau-Jan Chyan; Burkhard Poeggeler; Margarita Dubocovich; Roger Bick; George Perry; Felix Cruz-Sanchez; Mark A. Smith
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors.
Journal of pineal research 2002;32(3):135-42.
2002: Marin Guentchev; Sandra L Siedlak; Christa Jarius; Fabrizio Tagliavini; Rudy J Castellani; George Perry; Mark A. Smith; Herbert Budka
Oxidative damage to nucleic acids in human prion disease.
Neurobiology of disease 2002;9(3):275-81.
2002: Jun-ichi Kakimura; Yoshihisa Kitamura; Kazuyuki Takata; Masaaki Umeki; Sanae Suzuki; Keiichi Shibagaki; Takashi Taniguchi; Yasuyuki Nomura; Peter J Gebicke-Haerter; Mark A. Smith; George Perry; Shun Shimohama
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):601-3.
2002: Akio Kikuchi; Atsushi Takeda; Hiroshi Onodera; Teiko Kimpara; Kinya Hisanaga; Nobuyuki Sato; Akihiko Nunomura; Rudy J Castellani; George Perry; Mark A. Smith; Yasuto Itoyama
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.
Neurobiology of disease 2002;9(2):244-8.
2002: Osamu Ogawa; George Perry; Mark A. Smith
The "Down's" side of mitochondria.
Developmental cell 2002;2(3):255-6.
2002: Mar Pérez; Félix Hernández; Alberto Gómez-Ramos; Mark A. Smith; George Perry; Jesús Avila
Formation of aberrant phosphotau fibrillar polymers in neural cultured cells.
European journal of biochemistry / FEBS 2002;269(5):1484-9.
2002: Roberta Borghi; Luca Giliberto; Andrea Assini; André Delacourte; George Perry; Mark A. Smith; Paola Strocchi; Damiano Zaccheo; Massimo Tabaton
Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy.
Neurology 2002;58(4):589-92.
2002: Takafumi Wataya; Akihiko Nunomura; Mark A. Smith; Sandra L Siedlak; Peggy L R Harris; Shun Shimohama; Luke I Szweda; Matthew A Kaminski; Jesús Avila; Donald L Price; Don W Cleveland; Lawrence M Sayre; George Perry
High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal.
The Journal of biological chemistry 2002;277(7):4644-8.
2002: Rudy J Castellani; George Perry; Sandra L Siedlak; Akihiko Nunomura; Shun Shimohama; Jing Zhang; Thomas J Montine; Lawrence M Sayre; Mark A. Smith
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans.
Neuroscience letters 2002;319(1):25-8.
2002: Kimberly L Clapp-Lilly; Mark A. Smith; George Perry; Peggy L Harris; Xiongwei Zhu; Kelly L Drew; Lawrence K Duffy
Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity.
International journal of circumpolar health 2002;61(1):32-40.
2002: George Perry; Akihiko Nunomura; Adam D Cash; Marta A Taddeo; Keisuke Hirai; Gjumrakch Aliev; Jesús Avila; Takafumi Wataya; Shun Shimohama; Craig S Atwood; Mark A. Smith
Reactive oxygen: its sources and significance in Alzheimer disease.
Journal of neural transmission. Supplementum 2002;(62):69-75.
2002: Glenda M Bishop; Stephen R Robinson; Quan Liu; George Perry; Craig S Atwood; Mark A. Smith
Iron: a pathological mediator of Alzheimer disease?
Developmental neuroscience 2002;24(2-3):184-7.
2002: J Zhang; Thomas J Montine; Mark A. Smith; S L Siedlak; G Gu; David Robertson; George Perry
The mitochondrial common deletion in Parkinson's disease and related movement disorders.
Parkinsonism & related disorders 2002;8(3):165-70.
2002: George Perry; Lawrence M Sayre; Craig S Atwood; Rudy J Castellani; Adam D Cash; Catherine A Rottkamp; Mark A. Smith
The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications.
CNS drugs 2002;16(5):339-52.
2002: Gjumrakch Aliev; Mark A. Smith; Dilara Seyidova; Maxwell Neal; Jiong Shi; Marilena Loizidou; Mark Turmaine; Robert P Friedland; I Taylor; G Burnstock; George Perry; Joseph C LaManna
Increased expression of NOS and ET-1 immunoreactivity in human colorectal metastatic liver tumours is associated with selective depression of constitutive NOS immunoreactivity in vessel endothelium.
Journal of submicroscopic cytology and pathology 2002;34(1):37-50.
2002: Gjumrakch Aliev; Mark A. Smith; Dilara Seyidov; Maxwell Neal; Bruce Lamb; Akihiko Nunomura; Eldar K Gasimov; Harry V Vinters; George Perry; Joseph C LaManna; Robert P Friedland
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease.
Brain pathology (Zurich, Switzerland) 2002;12(1):21-35.
2001: Angelika Bierhaus; Stephan Schiekofer; Markus Schwaninger; Martin Andrassy; Per M Humpert; Jiang Chen; M Hong; Thomas Luther; Thomas Henle; I Klöting; Michael Morcos; Michael Hofmann; Hans Tritschler; B Weigle; Michael Kasper; Mark A. Smith; George Perry; Ann Marie Schmidt; David M Stern; Hans-Ulrich Häring; Erwin Schleicher; Peter P Nawroth
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Diabetes 2001;50(12):2792-808.
2001: Xiongwei Zhu; Rudy J Castellani; Atsushi Takeda; Akihiko Nunomura; Craig S Atwood; George Perry; Mark A. Smith
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
Mechanisms of ageing and development 2001;123(1):39-46.
2001: Xiongwei Zhu; Catherine A Rottkamp; Anthony W Hartzler; Zheng Sun; Atsushi Takeda; H Boux; Shun Shimohama; George Perry; Mark A. Smith
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
Journal of neurochemistry 2001;79(2):311-8.
2001: Gjumrakch Aliev; Mark A. Smith; Mark Turmaine; Maxwell Neal; T V Zimina; Robert P Friedland; George Perry; Joseph C LaManna; G Burnstock
Atherosclerotic lesions are associated with increased immunoreactivity for inducible nitric oxide synthase and endothelin-1 in thoracic aortic intimal cells of hyperlipidemic Watanabe rabbits.
Experimental and molecular pathology 2001;71(1):40-54.
2001: Akihiko Nunomura; George Perry; Gjumrakch Aliev; Keisuke Hirai; Atsushi Takeda; Elizabeth Balraj; Paul K Jones; Hossein A Ghanbari; Takafumi Wataya; Shun Shimohama; S Chiba; Craig S Atwood; Robert B Petersen; Mark A. Smith
Oxidative damage is the earliest event in Alzheimer disease.
Journal of neuropathology and experimental neurology 2001;60(8):759-67.
2001: Rudy J Castellani; Peggy L R Harris; Lawrence M Sayre; J Fujii; N Taniguchi; Michael P. Vitek; H Founds; Craig S Atwood; George Perry; Mark A. Smith
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
Free radical biology & medicine 2001;31(2):175-80.
2001: Miguel Pappolla; RA Omar; Yau-Jan Chyan; Jorge Ghiso; K Hsiao; Peter Bozner; George Perry; Mark A. Smith; Felix Cruz-Sanchez
Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".
Journal of neurochemistry 2001;78(1):121-8.
2001: F Zhou; Xiongwei Zhu; Rudy J Castellani; R Stimmelmayr; George Perry; Mark A. Smith; Kelly L Drew
Hibernation, a model of neuroprotection.
The American journal of pathology 2001;158(6):2145-51.
2001: Lawrence M Sayre; Mark A. Smith; George Perry
Chemistry and biochemistry of oxidative stress in neurodegenerative disease.
Current medicinal chemistry 2001;8(7):721-38.
2001: Arezoo Campbell; Mark A. Smith; Lawrence M Sayre; Stephen C Bondy; George Perry
Mechanisms by which metals promote events connected to neurodegenerative diseases.
Brain research bulletin 2001;55(2):125-32.
2001: Kimberly L Clapp-Lilly; Mark A. Smith; George Perry; P L Harris; Xiongwei Zhu; Lawrence K Duffy
Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.
Neuroreport 2001;12(6):1277-80.
2001: Keisuke Hirai; Gjumrakch Aliev; Akihiko Nunomura; Hisashi Fujioka; RL Russell; Craig S Atwood; A B Johnson; Y Kress; Harry V Vinters; Massimo Tabaton; Shun Shimohama; Adam D Cash; Sandra L Siedlak; Peggy L R Harris; Paul K Jones; Robert B Petersen; George Perry; Mark A. Smith
Mitochondrial abnormalities in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(9):3017-23.
2001: Arun K Raina; A Hochman; Xiongwei Zhu; Catherine A Rottkamp; Akihiko Nunomura; Sandra L Siedlak; H Boux; Rudy J Castellani; George Perry; Mark A. Smith
Abortive apoptosis in Alzheimer's disease.
Acta neuropathologica 2001;101(4):305-10.
2001: Boon-Seng Wong; Tong Liu; Derek Paisley; Ruliang Li; Tao Pan; S G Chen; George Perry; Robert B Petersen; Mark A. Smith; David W Melton; Pierluigi Gambetti; David Brown; Man-Sun Sy
Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function.
Molecular and cellular neurosciences 2001;17(4):768-75.
2001: Yakup Alicigüzel; S N Ozdem; Sebahat Ozdem; Umit Karayalçin; S L Siedlak; George Perry; Mark A. Smith
Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients.
Free radical biology & medicine 2001;30(6):665-70.
2001: Kimberly L Clapp-Lilly; Mark A. Smith; George Perry; Lawrence K Duffy
Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices.
Chemico-biological interactions 2001;134(1):101-7.
2001: Catherine A Rottkamp; Arun K Raina; Xiongwei Zhu; E Gaier; Ashley I Bush; Craig S Atwood; M Chevion; George Perry; Mark A. Smith
Redox-active iron mediates amyloid-beta toxicity.
Free radical biology & medicine 2001;30(4):447-50.
2001: George Perry; Jesús Avila; M G Espey; D A Wink; Craig S Atwood; Mark A. Smith
Biochemistry of neurodegeneration.
Science (New York, N.Y.) 2001;291(5504):595-7.
2001: Gjumrakch Aliev; D Seyidov; Maxwell Neal; Jiong Shi; T Vigan; A Hernandez; G Folco; A H Soas; T V Zimina; Mark A. Smith; George Perry; Joseph C LaManna; Robert P Friedland
The effect of agonists and antagonists on the morphology of non-transformed human smooth muscle cell in vitro.
Journal of submicroscopic cytology and pathology 2001;33(1-2):141-9.
2001: Yakup Alicigüzel; S Ozdem; A Y Demir; F Unal; D Kumbul; Sebahat Ozdem; George Perry; Mark A. Smith
Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymes in vitro.
Redox report : communications in free radical research 2001;6(3):153-4.
2001: Boon-Seng Wong; Tong Liu; Ruliang Li; Tao Pan; Robert B Petersen; Mark A. Smith; Pierluigi Gambetti; George Perry; Jean C Manson; David Brown; Man-Sun Sy
Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein.
Journal of neurochemistry 2001;76(2):565-72.
2001: Xiongwei Zhu; Arun K Raina; Catherine A Rottkamp; Gjumrakch Aliev; George Perry; H Boux; Mark A. Smith
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
Journal of neurochemistry 2001;76(2):435-41.
2001: James A Joseph; Barbara Shukitt-Hale; Natalia Crivello; A Martin; George Perry; Mark A. Smith
Copernicus revisited: amyloid beta in Alzheimer's disease.
Neurobiology of aging 2001;22(1):131-46.
2001: George Perry; Xiongwei Zhu; Mark A. Smith
Do neurons have a choice in death?
The American journal of pathology 2001;158(1):1-2.
2000: Mar Pérez; Raquel Cuadros; Mark A. Smith; George Perry; Jesús Avila
Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal.
FEBS letters 2000;486(3):270-4.
2000: Alex L Mah; George Perry; Mark A. Smith; Mervyn Monteiro
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation.
The Journal of cell biology 2000;151(4):847-62.
2000: Akihiko Nunomura; George Perry; Miguel Pappolla; Robert P Friedland; Keisuke Hirai; S Chiba; Mark A. Smith
Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome.
Journal of neuropathology and experimental neurology 2000;59(11):1011-7.
2000: Xiongwei Zhu; Catherine A Rottkamp; H Boux; Atsushi Takeda; George Perry; Mark A. Smith
Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease.
Journal of neuropathology and experimental neurology 2000;59(10):880-8.
2000: Gjumrakch Aliev; Jiong Shi; George Perry; Robert P Friedland; Joseph C LaManna
Decreased constitutive nitric oxide synthase, but increased inducible nitric oxide synthase and endothelin-1 immunoreactivity in aortic endothelial cells of donryu rats on a cholesterol-enriched diet.
The Anatomical record 2000;260(1):16-25.
2000: Atsushi Takeda; Mark A. Smith; Jesús Avila; Akihiko Nunomura; Sandra L Siedlak; Xiongwei Zhu; George Perry; Lawrence M Sayre
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Journal of neurochemistry 2000;75(3):1234-41.
2000: Rudy J Castellani; Sandra L Siedlak; George Perry; Mark A. Smith
Sequestration of iron by Lewy bodies in Parkinson's disease.
Acta neuropathologica 2000;100(2):111-4.
2000: Catherine A Rottkamp; Akihiko Nunomura; Keisuke Hirai; Lawrence M Sayre; George Perry; Mark A. Smith
Will antioxidants fulfill their expectations for the treatment of Alzheimer disease?
Mechanisms of ageing and development 2000;116(2-3):169-79.
2000: Mark A. Smith; Catherine A Rottkamp; Akihiko Nunomura; Arun K Raina; George Perry
Oxidative stress in Alzheimer's disease.
Biochimica et biophysica acta 2000;1502(1):139-44.
2000: George Perry; Akihiko Nunomura; K Hirai; Atsushi Takeda; Gjumrakch Aliev; Mark A. Smith
Oxidative damage in Alzheimer's disease: the metabolic dimension.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(4-5):417-21.
2000: Math P Cuajungco; Lee E Goldstein; Akihiko Nunomura; Mark A. Smith; JT Lim; Craig S Atwood; Xudong Huang; Y W Farrag; George Perry; Ashley I Bush
Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.
The Journal of biological chemistry 2000;275(26):19439-42.
2000: Shun Shimohama; Hiroko Tanino; N Kawakami; N Okamura; H Kodama; T Yamaguchi; Takao Hayakawa; Akihiko Nunomura; S Chiba; George Perry; Mark A. Smith; Shimpei Fujimoto
Activation of NADPH oxidase in Alzheimer's disease brains.
Biochemical and biophysical research communications 2000;273(1):5-9.
2000: Lawrence M Sayre; George Perry; Craig S Atwood; Mark A. Smith
The role of metals in neurodegenerative diseases.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(4):731-41.
2000: George Perry
Medicinal chemistry of neurodegenerative diseases--fourth international symposium. 30 January-2 February 2000, Cancun, Mexico.
IDrugs : the investigational drugs journal 2000;3(5):485-9.
2000: Patrizio Odetti; Silvano Garibaldi; R Norese; G Angelini; Lucio Marinelli; Sabina Valentini; Stefano Menini; Nicola Traverso; Damiano Zaccheo; Sandra L Siedlak; George Perry; Mark A. Smith; Massimo Tabaton
Lipoperoxidation is selectively involved in progressive supranuclear palsy.
Journal of neuropathology and experimental neurology 2000;59(5):393-7.
2000: George Perry; Mark A. Smith
Promises and pitfalls of therapeutics to modify oxidant balance in chronic disease.
IDrugs : the investigational drugs journal 2000;3(4):371-2.
2000: Robert P Friedland; Jiong Shi; Joseph C LaManna; Mark A. Smith; George Perry
Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;903():123-8.
2000: Jiong Shi; George Perry; Mark A. Smith; Robert P Friedland
Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease.
Neurobiology of aging 2000;21(2):357-61.
2000: George Perry; Arun K Raina; Akihiko Nunomura; Takafumi Wataya; Lawrence M Sayre; Mark A. Smith
How important is oxidative damage? Lessons from Alzheimer's disease.
Free radical biology & medicine 2000;28(5):831-4.
2000: George Perry; Akihiko Nunomura; Arun K Raina; Mark A. Smith
Amyloid-beta junkies.
Lancet 2000;355(9205):757.
2000: Atsushi Takeda; George Perry; N G Abraham; Barney E Dwyer; R K Kutty; J T Laitinen; Robert B Petersen; Mark A. Smith
Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau.
The Journal of biological chemistry 2000;275(8):5395-9.
2000: Arun K Raina; George Perry; Akihiko Nunomura; Lawrence M Sayre; Mark A. Smith
Histochemical and immunocytochemical approaches to the study of oxidative stress.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(2):93-7.
2000: Rudy J Castellani; Peggy L R Harris; Anne Lecroisey; Nadia Izadi-Pruneyre; Cécile Wandersman; George Perry; Mark A. Smith
Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease.
Antioxidants & redox signaling 2000;2(1):137-42.
2000: H T Kim; RL Russell; Arun K Raina; Peggy L R Harris; Sandra L Siedlak; Xiongwei Zhu; Robert B Petersen; Shun Shimohama; Mark A. Smith; George Perry
Protein disulfide isomerase in Alzheimer disease.
Antioxidants & redox signaling 2000;2(3):485-9.
2000: Mark A. Smith; Akihiko Nunomura; Xiongwei Zhu; Atsushi Takeda; George Perry
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease.
Antioxidants & redox signaling 2000;2(3):413-20.
2000: Mark A. Smith; James A Joseph; George Perry
Arson. Tracking the culprit in Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;924():35-8.
2000: Catherine A Rottkamp; Akihiko Nunomura; Arun K Raina; Lawrence M Sayre; George Perry; Mark A. Smith
Oxidative stress, antioxidants, and Alzheimer disease.
Alzheimer disease and associated disorders 2000;14 Suppl 1():S62-6.
2000: Lawrence M Sayre; George Perry; Peggy L R Harris; Y Liu; K A Schubert; Mark A. Smith
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals.
Journal of neurochemistry 2000;74(1):270-9.
1999: Sabina Capellari; Syed I A Zaidi; C B Urig; George Perry; Mark A. Smith; Robert B Petersen
Prion protein glycosylation is sensitive to redox change.
The Journal of biological chemistry 1999;274(49):34846-50.
1999: Mark A. Smith; Grace J Petot; George Perry
Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease.
Journal of Alzheimer's disease : JAD 1999;1(4-5):203-6.
1999: Jiong Shi; George Perry; Gjumrakch Aliev; Mark A. Smith; Karen K. Hsiao Ashe; Robert P Friedland
Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model.
Neuroreport 1999;10(15):3229-32.
1999: RL Russell; Sandra L Siedlak; Arun K Raina; J M Bautista; Mark A. Smith; George Perry
Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease.
Archives of biochemistry and biophysics 1999;370(2):236-9.
1999: George Perry
Neuronal apoptosis--ISN satellite symposium. 5-7 August 1999, Tübingen, Germany.
IDrugs : the investigational drugs journal 1999;2(10):992-4.
1999: Gjumrakch Aliev; E Ragazzi; Mark A. Smith; A Mironov; George Perry
Morphological features of regeneration of rabbit aortic endothelium after cryoinduced vascular damage.
Journal of submicroscopic cytology and pathology 1999;31(4):495-502.
1999: Rudy J Castellani; George Perry; David S Brenner; Mark A. Smith
Alexander disease: Alzheimer disease of the developing brain?
Alzheimer disease and associated disorders 1999;13(4):232-5.
1999: George Perry; H Roder; Akihiko Nunomura; Atsushi Takeda; Avi Friedlich; Xiongwei Zhu; Arun K Raina; N Holbrook; Sandra L Siedlak; P L Harris; Mark A. Smith
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.
Neuroreport 1999;10(11):2411-5.
1999: Mark A. Smith; Akihiko Nunomura; Atsushi Takeda; George Perry
Asking the right questions.
Science (New York, N.Y.) 1999;285(5428):665.
1999: Rudy J Castellani; Mark A. Smith; Akihiko Nunomura; Peggy L R Harris; George Perry
Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
Free radical biology & medicine 1999;26(11-12):1508-12.
1999: J Zhang; George Perry; Mark A. Smith; David Robertson; Sandra J Olson; DG Graham; Thomas J Montine
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons.
The American journal of pathology 1999;154(5):1423-9.
1999: Arun K Raina; Atsushi Takeda; Akihiko Nunomura; George Perry; Mark A. Smith
Genetic evidence for oxidative stress in Alzheimer's disease.
Neuroreport 1999;10(6):1355-7.
1999: Lawrence M Sayre; George Perry; Mark A. Smith
Redox metals and neurodegenerative disease.
Current opinion in chemical biology 1999;3(2):220-5.
1999: Akihiko Nunomura; George Perry; Miguel Pappolla; Ramon Wade; Keisuke Hirai; S Chiba; Mark A. Smith
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(6):1959-64.
1999: Todd E Morgan; Z Xie; SK Goldsmith; T Yoshida; A S Lanzrein; D Stone; Irina Rozovsky; George Perry; Mark A. Smith; Caleb E Finch
The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction.
Neuroscience 1999;89(3):687-99.
1999: George Perry; Mark A. Smith
[Is the lesion produced by oxidation a central part in the pathogenesis of Alzheimer's disease?].
Neurología (Barcelona, Spain) 1999;14(2):78-84.
1999: Arun K Raina; Dennis J Templeton; JC Deak; George Perry; Mark A. Smith
Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease.
Redox report : communications in free radical research 1999;4(1-2):23-7.
1999: Akihiko Nunomura; George Perry; K Hirai; Gjumrakch Aliev; Atsushi Takeda; S Chiba; Mark A. Smith
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
Annals of the New York Academy of Sciences 1999;893():362-4.
1999: Lawrence M Sayre; George Perry; Mark A. Smith
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
Methods in enzymology 1999;309():133-52.
1999: JL Gerst; Sandra L Siedlak; Akihiko Nunomura; Rudy J Castellani; George Perry; Mark A. Smith
Role of oxidative stress in frontotemporal dementia.
Dementia and geriatric cognitive disorders 1999;10 Suppl 1():85-7.
1999: X Chen; D Eswaran; Mark A. Smith; George Perry; V E Anderson
Universal isolation of cross-linked peptides: application to neurofibrillary tangles.
Bioconjugate chemistry 1999;10(1):112-8.
1998: M E Velasco; Mark A. Smith; Sandra L Siedlak; Akihiko Nunomura; George Perry
Striation is the characteristic neuritic abnormality in Alzheimer disease.
Brain research 1998;813(2):329-33.
1998: Mark A. Smith; George Perry
What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?
Journal of chemical neuroanatomy 1998;16(1):35-41.
1998: Mark A. Smith; Milan Vasák; Markus Knipp; Rudy J Castellani; George Perry
Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease.
Free radical biology & medicine 1998;25(8):898-902.
1998: George Perry; Akihiko Nunomura; P Lucassen; H Lassmann; Mark A. Smith
Apoptosis and Alzheimer's disease.
Science (New York, N.Y.) 1998;282(5392):1268-9.
1998: Naoki Hattori; Kaori Kitagawa; T Higashida; Kyoko Yagyu; Shun Shimohama; T Wataya; George Perry; Mark A. Smith; Chiyoko Inagaki
CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains.
Neuroscience letters 1998;254(3):141-4.
1998: Jorge Guevara; Blanca Espinosa; Edgar Zenteno; L Vázguez; José Luna; George Perry; Raúl Mena
Altered glycosylation pattern of proteins in Alzheimer disease.
Journal of neuropathology and experimental neurology 1998;57(10):905-14.
1998: George Perry; Akihiko Nunomura; Mark A. Smith
A suicide note from Alzheimer disease neurons?
Nature medicine 1998;4(8):897-8.
1998: George Perry; Mark A. Smith
Is oxidative damage central to the pathogenesis of Alzheimer disease?
Acta neurologica Belgica 1998;98(2):175-9.
1998: Mark A. Smith; Lawrence M Sayre; V E Anderson; P L Harris; M Flint Beal; Neil W Kowall; George Perry
Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(6):731-5.
1998: Mark A. Smith; K Hirai; K Hsiao; Miguel Pappolla; Peggy L R Harris; Sandra L Siedlak; Massimo Tabaton; George Perry
Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Journal of neurochemistry 1998;70(5):2212-5.
1998: George Perry; Mark A. Smith; C E McCann; Sandra L Siedlak; Paul K Jones; Robert P Friedland
Cerebrovascular muscle atrophy is a feature of Alzheimer's disease.
Brain research 1998;791(1-2):63-6.
1998: Miguel Pappolla; Yau-Jan Chyan; RA Omar; K Hsiao; George Perry; Mark A. Smith; Peter Bozner
Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.
The American journal of pathology 1998;152(4):871-7.
1998: Mark A. Smith; K Wehr; Peggy L R Harris; Sandra L Siedlak; James Connor; George Perry
Abnormal localization of iron regulatory protein in Alzheimer's disease.
Brain research 1998;788(1-2):232-6.
1998: Rudy J Castellani; George Perry; Peggy L R Harris; M L Cohen; Lawrence M Sayre; R G Salomon; Mark A. Smith
Advanced lipid peroxidation end-products in Alexander's disease.
Brain research 1998;787(1):15-8.
1998: Patrizio Odetti; G Angelini; D Dapino; Damiano Zaccheo; Silvano Garibaldi; Franca Dagna Bricarelli; G Piombo; George Perry; Mark A. Smith; Nicola Traverso; Massimo Tabaton
Early glycoxidation damage in brains from Down's syndrome.
Biochemical and biophysical research communications 1998;243(3):849-51.
1998: D A DeWitt; George Perry; M Cohen; Catherine M Doller; Jerry Silver
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease.
Experimental neurology 1998;149(2):329-40.
1998: Yoshihisa Kitamura; Shun Shimohama; W Kamoshima; T Ota; Yasuji Matsuoka; Yasuyuki Nomura; Mark A. Smith; George Perry; Peter J Whitehouse; Tadatsugu Taniguchi
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.
Brain research 1998;780(2):260-9.
1998: Gerald Münch; Reinhard Schinzel; Claudia Loske; A Wong; Nuria Durany; J J Li; H Vlassara; Mark A. Smith; George Perry; Peter Riederer
Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(4-5):439-61.
1997: Mark A. Smith; P L Harris; Lawrence M Sayre; George Perry
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9866-8.
1997: Rudy J Castellani; George Perry; Peggy L R Harris; V M Monnier; M L Cohen; Mark A. Smith
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease.
Neuroscience letters 1997;231(2):79-82.
1997: Mark A. Smith; Ram H Nagaraj; George Perry
Protocol for quantitative analysis of paired helical filament solubilization: a method applicable to insoluble amyloids and inclusion bodies.
Brain research. Brain research protocols 1997;1(3):247-52.
1997: Robert G Salomon; Ganesamoorthy Subbanagounder; June O'Neil; K Kaur; Mark A. Smith; Henry F Hoff; George Perry; V M Monnier
Levuglandin E2-protein adducts in human plasma and vasculature.
Chemical research in toxicology 1997;10(5):536-45.
1997: Lawrence M Sayre; Michael G Zagorski; Witold K Surewicz; G A Krafft; George Perry
Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal.
Chemical research in toxicology 1997;10(5):518-26.
1997: Lawrence M Sayre; D A Zelasko; Peggy L R Harris; George Perry; Robert G Salomon; Mark A. Smith
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.
Journal of neurochemistry 1997;68(5):2092-7.
1997: Mark A. Smith; P L Richey Harris; Lawrence M Sayre; J S Beckman; George Perry
Widespread peroxynitrite-mediated damage in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(8):2653-7.
1997: Massimo Tabaton; George Perry; Mark A. Smith; Michael P. Vitek; G Angelini; D Dapino; Silvano Garibaldi; Damiano Zaccheo; Patrizio Odetti
Is amyloid beta-protein glycated in Alzheimer's disease?
Neuroreport 1997;8(4):907-9.
1997: Mark A. Smith; George Perry
The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis.
Journal of neuropathology and experimental neurology 1997;56(2):217.
1996: Rudy J Castellani; Mark A. Smith; P L Richey; George Perry
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Brain research 1996;737(1-2):195-200.
1996: Mark A. Smith; Massimo Tabaton; George Perry
Early contribution of oxidative glycation in Alzheimer disease.
Neuroscience letters 1996;217(2-3):210-1.
1996: J Xiao; George Perry; Juan C Troncoso; Mervyn Monteiro
alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease.
Journal of neuropathology and experimental neurology 1996;55(9):954-63.
1996: Mark A. Smith; George Perry; P L Richey; Lawrence M Sayre; V E Anderson; M Flint Beal; Neil W Kowall
Oxidative damage in Alzheimer's.
Nature 1996;382(6587):120-1.
1996: Mark A. Smith; Lawrence M Sayre; Vincent M Monnier; George Perry
Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1996;28(1-3):41-8.
1996: Mark A. Smith; Sandra L Siedlak; P L Richey; Ram H Nagaraj; A Elhammer; George Perry
Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease.
Brain research 1996;717(1-2):99-108.
1996: S M Ali; Sandra L Siedlak; P A Gonzalez-DeWhitt; R A Altman; J M Glendening; D E Lowery; Mary J Savage; H G Polites; George Perry; Barry D Greenberg
Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice.
Neurobiology of aging 1996;17(2):223-34.
1996: Barry D Greenberg; Mary J Savage; D S Howland; S M Ali; Sandra L Siedlak; George Perry; R Siman; Richard W Scott
APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology.
Neurobiology of aging 1996;17(2):153-71.
1996: Mark A. Smith; C E Dunbar; E J Miller; George Perry
Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1996;27(2):145-54.
1996: Mark A. Smith; Lawrence M Sayre; George Perry
Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link.
Diabetologia 1996;39(2):247.
1996: Mark A. Smith; P L Richey; Rajesh N. Kalaria; George Perry
Elastase is associated with the neurofibrillary pathology of Alzheimer disease: a putative link between proteolytic imbalance and oxidative stress.
Restorative neurology and neuroscience 1996;9(4):213-7.
1996: Mark A. Smith; George Perry
Alzheimer disease: protein-protein interaction and oxidative stress.
Boletín de estudios médicos y biológicos 1996;44(1-4):5-10.
1996: D Praprotnik; Mark A. Smith; P L Richey; Harry V Vinters; George Perry
Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease.
Acta neuropathologica 1996;91(3):226-35.
1996: D Praprotnik; Mark A. Smith; P L Richey; Harry V Vinters; George Perry
Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress.
Acta neuropathologica 1996;91(1):1-5.
1996: Giorgio Giaccone; B Pedrotti; antonio migheli; L Verga; J Perez; G Racagni; Mark A. Smith; George Perry; Luca De Gioia; C Selvaggini; Mario Salmona; Jorge Ghiso; Blas Frangione; K Islam; Orso Bugiani; Fabrizio Tagliavini
beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease.
The American journal of pathology 1996;148(1):79-87.
1995: Mark A. Smith; George Perry
Free radical damage, iron, and Alzheimer's disease.
Journal of the neurological sciences 1995;134 Suppl():92-4.
1995: Shun Shimohama; Shimpei Fujimoto; M Chachin; Tadatsugu Taniguchi; George Perry; Peter J Whitehouse; J Kimura
Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease.
Brain research 1995;699(1):125-9.
1995: Rudy J Castellani; Mark A. Smith; P L Richey; Rajesh N. Kalaria; Pierluigi Gambetti; George Perry
Evidence for oxidative stress in Pick disease and corticobasal degeneration.
Brain research 1995;696(1-2):268-71.
1995: Mark S Kindy; A R King; George Perry; Maria C de Beer; Frederick C de Beer
Association of apolipoprotein E with murine amyloid A protein amyloid.
Laboratory investigation; a journal of technical methods and pathology 1995;73(4):469-75.
1995: Massimo Tabaton; Marina Rolleri; P Masturzo; S Cammarata; G Angelini; Lawrence A Hansen; T Saitoh; Robert B Petersen; George Perry; P Richey
Apolipoprotein E epsilon 4 allele frequency is not increased in progressive supranuclear palsy.
Neurology 1995;45(9):1764-5.
1995: DR Premkumar; Mark A. Smith; P L Richey; Robert B Petersen; Rudy J Castellani; R K Kutty; B Wiggert; George Perry; Rajesh N. Kalaria
Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
Journal of neurochemistry 1995;65(3):1399-402.
1995: Mark A. Smith; V M Monnier; Lawrence M Sayre; George Perry
Amyloidosis, advanced glycation end products and Alzheimer disease.
Neuroreport 1995;6(12):1595-6.
1995: Shi Du Yan; Shi Fang Yan; Xi Chen; J Fu; M Chen; P Kuppusamy; Mark A. Smith; George Perry; GC Godman; P Nawroth
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.
Nature medicine 1995;1(7):693-9.
1995: Shun Shimohama; Shimpei Fujimoto; H Matsushima; T Takenawa; Tadatsugu Taniguchi; George Perry; Peter J Whitehouse; J Kimura
Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease.
Journal of neurochemistry 1995;64(6):2629-34.
1995: R P Rifenburg; George Perry
Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(2):235-7.
1995: Mark A. Smith; M Rudnicka-Nawrot; P L Richey; D Praprotnik; P Mulvihill; C A Miller; Lawrence M Sayre; George Perry
Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease.
Journal of neurochemistry 1995;64(6):2660-6.
1995: Mark A. Smith; Lawrence M Sayre; V M Monnier; George Perry
Radical AGEing in Alzheimer's disease.
Trends in neurosciences 1995;18(4):172-6.
1995: Mark A. Smith; Lawrence M Sayre; Michael P. Vitek; V M Monnier; George Perry
Early AGEing and Alzheimer's.
Nature 1995;374(6520):316.
1995: P L Richey; Sandra L Siedlak; Mark A. Smith; George Perry
Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis.
Biochemical and biophysical research communications 1995;208(2):657-63.
1995: Mark A. Smith; P L Richey; R K Kutty; B Wiggert; George Perry
Ultrastructural localization of heme oxygenase-1 to the neurofibrillary pathology of Alzheimer disease.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;24(2-3):227-30.
1995: Shun Shimohama; George Perry; P Richey; D Praprotnik; T Takenawa; K Fukami; Peter J Whitehouse; J Kimura
Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles.
Brain research 1995;669(2):217-24.
1995: P Cras; Mark A. Smith; P L Richey; Sandra L Siedlak; P Mulvihill; George Perry
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.
Acta neuropathologica 1995;89(4):291-5.
1994: Pierluigi Gambetti; George Perry
Alzheimer's disease and prion proteins: a meeting made in muscle.
The American journal of pathology 1994;145(6):1261-4.
1994: Mark A. Smith; P L Richey; S Taneda; R K Kutty; Lawrence M Sayre; Vincent M Monnier; George Perry
Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease.
Annals of the New York Academy of Sciences 1994;738():447-54.
1994: D A DeWitt; P L Richey; D Praprotnik; Jerry Silver; George Perry
Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases.
Brain research 1994;656(1):205-9.
1994: Mark A. Smith; R K Kutty; P L Richey; Shi Du Yan; D Stern; G J Chader; B Wiggert; Robert B Petersen; George Perry
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
The American journal of pathology 1994;145(1):42-7.
1994: Mark A. Smith; S Taneda; P L Richey; S Miyata; Shi Du Yan; D Stern; Lawrence M Sayre; Vincent M Monnier; George Perry
Advanced Maillard reaction end products are associated with Alzheimer disease pathology.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5710-4.
1994: Mark A. Smith; George Perry
Alzheimer disease: an imbalance of proteolytic regulation?
Medical hypotheses 1994;42(4):277-9.
1993: Rajesh N. Kalaria; George Perry
Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.
Brain research 1993;631(1):151-5.
1993: D R Canning; R J McKeon; D A DeWitt; George Perry; J R Wujek; R C Frederickson; Jerry Silver
beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth.
Experimental neurology 1993;124(2):289-98.
1993: J A Holash; S I Harik; George Perry; P A Stewart
Barrier properties of testis microvessels.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11069-73.
1993: George Perry; P L Richey; Sandra L Siedlak; Mark A. Smith; P Mulvihill; D A DeWitt; J Barnett; Barry D Greenberg; Rajesh N. Kalaria
Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease.
The American journal of pathology 1993;143(6):1586-93.
1993: Shun Shimohama; George Perry; P Richey; T Takenawa; Peter J Whitehouse; K Miyoshi; Toshihiko Suenaga; S Matsumoto; M Nishimura; J Kimura
Abnormal accumulation of phospholipase C-delta in filamentous inclusions of human neurodegenerative diseases.
Neuroscience letters 1993;162(1-2):183-6.
1993: Shun Shimohama; Shimpei Fujimoto; N Tresser; P Richey; George Perry; Peter J Whitehouse; Y Homma; T Takenawa; Tadatsugu Taniguchi; Toshihiko Suenaga
Aberrant phosphoinositide metabolism in Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():46-9.
1993: Rajesh N. Kalaria; S U Bhatti; W David Lust; George Perry
The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion.
Annals of the New York Academy of Sciences 1993;695():190-3.
1993: M Kawai; Rajesh N. Kalaria; P Cras; Sandra L Siedlak; M E Velasco; Earl R Shelton; H W Chan; Barry D Greenberg; George Perry
Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.
Brain research 1993;623(1):142-6.
1993: Rajesh N. Kalaria; todd golde; S N Kroon; George Perry
Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
The American journal of pathology 1993;143(3):886-93.
1993: Sangram S Sisodia; Edward H Koo; Paul N Hoffman; George Perry; Donald L Price
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(7):3136-42.
1993: Mark A. Smith; Rajesh N. Kalaria; George Perry
Alpha 1-trypsin immunoreactivity in Alzheimer disease.
Biochemical and biophysical research communications 1993;193(2):579-84.
1993: D A DeWitt; Jerry Silver; D R Canning; George Perry
Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease.
Experimental neurology 1993;121(2):149-52.
1993: George Perry
Neuritic plaques in Alzheimer disease originate from neurofibrillary tangles.
Medical hypotheses 1993;40(4):257-8.
1993: S I Harik; A K Hall; P Richey; L Andersson; P Lundahl; George Perry
Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system.
Brain research. Developmental brain research 1993;72(1):41-9.
1993: Marcello Villanova; M Kawai; Ursula Lübke; S J Oh; George Perry; J Six; Chantal Ceuterick; Jean-Jacques Martin; Patrick Cras
Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers.
Brain research 1993;603(2):343-7.
1993: Rajesh N. Kalaria; S U Bhatti; E A Palatinsky; D H Pennington; Earl R Shelton; H W Chan; George Perry; W David Lust
Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain.
Neuroreport 1993;4(2):211-4.
1993: S Cissé; George Perry; G Lacoste-Royal; Thérèse Cabana; D Gauvreau
Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains.
Acta neuropathologica 1993;85(3):233-40.
1992: Rajesh N. Kalaria; S N Kroon; I Grahovac; George Perry
Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease.
Neuroscience 1992;51(1):177-84.
1992: Massimo Tabaton; S Cammarata; T Mandybur; P Richey; M Kawai; George Perry; Pierluigi Gambetti
Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities.
Brain research 1992;593(2):299-303.
1992: M Kawai; P Cras; George Perry
Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution.
Brain research 1992;592(1-2):278-82.
1992: George Perry; P Richey; Sandra L Siedlak; P Galloway; M Kawai; P Cras
Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases.
Brain research 1992;579(2):350-2.
1992: M Kawai; P Cras; P Richey; Massimo Tabaton; D E Lowery; P A Gonzalez-DeWhitt; Barry D Greenberg; Pierluigi Gambetti; George Perry
Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease.
The American journal of pathology 1992;140(4):947-58.
1992: M Aikawa; A Brown; C D Smith; T Tegoshi; R J Howard; T H Hasler; Y Ito; George Perry; William E Collins; K Webster
A primate model for human cerebral malaria: Plasmodium coatneyi-infected rhesus monkeys.
The American journal of tropical medicine and hygiene 1992;46(4):391-7.
1992: P G Galloway; P Mulvihill; George Perry
Filaments of Lewy bodies contain insoluble cytoskeletal elements.
The American journal of pathology 1992;140(4):809-22.
1992: S Hirose; R P Mohney; S C Mutka; L Ravi; D R Singleton; George Perry; Alan M Tartakoff; M Edward Medof
Derivation and characterization of glycoinositol-phospholipid anchor-defective human K562 cell clones.
The Journal of biological chemistry 1992;267(8):5272-8.
1992: George Perry; P Cras; Sandra L Siedlak; Massimo Tabaton; M Kawai
Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease.
The American journal of pathology 1992;140(2):283-90.
1992: P A Gollin; Rajesh N. Kalaria; Piet Eikelenboom; A Rozemuller; George Perry
Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.
Neuroreport 1992;3(2):201-3.
1991: P Cras; George Perry
Dementia with argyrophilic grains.
Annals of neurology 1991;30(6):853-4.
1991: George Perry; Sandra L Siedlak; P Richey; M Kawai; P Cras; Rajesh N. Kalaria; P G Galloway; J M Scardina; Barbara Cordell; Barry D Greenberg
Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(11):3679-83.
1991: J Vande Weghe; P Cras; M Kawai; Sandra L Siedlak; Massimo Tabaton; Barry D Greenberg; George Perry
Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease.
Brain research 1991;560(1-2):303-5.
1991: P Cras; M Kawai; Sandra L Siedlak; George Perry
Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease.
Brain research 1991;558(2):312-4.
1991: P Cras; M Kawai; D Lowery; P Gonzalez-DeWhitt; Barry D Greenberg; George Perry
Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7552-6.
1991: J Gheuens; Patrick Cras; George Perry; J Boons; C Ceuterick-de Groote; Ursula Lübke; M Mercken; Massimo Tabaton; P L Gambetti; M Vandermeeren
Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases.
Brain research 1991;558(1):43-52.
1991: Sandra L Siedlak; P Cras; M Kawai; P Richey; George Perry
Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(7):899-904.
1991: George Perry; M Kawai; Massimo Tabaton; M Onorato; P Mulvihill; P Richey; A Morandi; J A Connolly; Pierluigi Gambetti
Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(6):1748-55.
1991: Rajesh N. Kalaria; P G Galloway; George Perry
Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders.
Neuropathology and applied neurobiology 1991;17(3):189-201.
1991: Massimo Tabaton; S Cammarata; G Mancardi; V Manetto; L Autilio-Gambetti; George Perry; Pierluigi Gambetti
Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2098-102.
1991: Massimo Tabaton; S Cammarata; G L Mancardi; Giuseppe Cordone; George Perry; C Loeb
Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease.
Neurology 1991;41(3):391-4.
1991: P G Galloway; George Perry
Tropomyosin distinguishes Lewy bodies of Parkinson disease from other neurofibrillary pathology.
Brain research 1991;541(2):347-9.
1991: M Kasper; George Perry; P Stosiek
Cytokeratin expression in human spinal meninges and ependymal cells.
Journal für Hirnforschung 1991;32(1):19-25.
1990: Greer M Murphy; LF Eng; William G Ellis; George Perry; L C Meissner; Jared R Tinklenberg
Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease.
Brain research 1990;537(1-2):102-8.
1990: S I Harik; Rajesh N. Kalaria; L Andersson; P Lundahl; George Perry
Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(12):3862-72.
1990: M Kawai; Rajesh N. Kalaria; S I Harik; George Perry
The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease.
The American journal of pathology 1990;137(6):1435-46.
1990: P G Galloway; P Mulvihill; Sandra L Siedlak; M Mijares; M Kawai; H Padget; R Kim; George Perry
Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease.
The American journal of pathology 1990;137(2):291-300.
1990: P Cras; M Kawai; Sandra L Siedlak; P Mulvihill; Pierluigi Gambetti; D Lowery; P Gonzalez-DeWhitt; Barry D Greenberg; George Perry
Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.
The American journal of pathology 1990;137(2):241-6.
1990: S I Harik; Rajesh N. Kalaria; P M Whitney; L Andersson; P Lundahl; S R Ledbetter; George Perry
Glucose transporters are abundant in cells with "occluding" junctions at the blood-eye barriers.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4261-4.
1990: P G Galloway; M J Likavec; George Perry
Immunohistochemical recognition of ethylnitrosourea induced rat brain microtumors by anti-Leu 7 monoclonal antibody.
Cancer letters 1990;49(3):243-8.
1990: H Kawahara; Monique Cadrin; George Perry; L Autilio-Gambetti; S H Swierenga; J Metuzals; Normand Marceau; S W French
Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion.
Hepatology (Baltimore, Md.) 1990;11(3):435-48.
1990: P G Galloway; M J Likavec; George Perry
Tropomyosin isoform expression in normal and neoplastic astrocytes.
Laboratory investigation; a journal of technical methods and pathology 1990;62(2):163-70.
1990: M Kasper; H J Terpe; George Perry
Age-dependent pattern of intermediate filament protein expression in the human pineal gland.
Journal für Hirnforschung 1990;31(2):215-21.
1989: Massimo Tabaton; T I Mandybur; George Perry; M Onorato; L Autilio-Gambetti; Pierluigi Gambetti
The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition.
Annals of neurology 1989;26(6):771-8.
1989: M R Palmert; Sandra L Siedlak; Marcia B Podlisny; Barry D Greenberg; Earl R Shelton; H W Chan; M Usiak; Dennis J Selkoe; George Perry; Steven G Younkin
Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.
Biochemical and biophysical research communications 1989;165(1):182-8.
1989: Massimo Tabaton; S Cammarata; V Manetto; George Perry; G Mancardi
Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease.
Neuroscience letters 1989;103(3):259-62.
1989: P G Galloway; C Bergeron; George Perry
The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease.
Neuroscience letters 1989;100(1-3):6-10.
1989: George Perry; P Mulvihill; V A Fried; HT Smith; Inge Grundke-Iqbal; Khalid Iqbal
Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease.
Journal of neurochemistry 1989;52(5):1523-8.
1989: P Mulvihill; George Perry
Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau.
Brain research 1989;484(1-2):150-6.
1989: V Manetto; Fadi W Abdul-Karim; George Perry; Massimo Tabaton; L Autilio-Gambetti; Pierluigi Gambetti
Selective presence of ubiquitin in intracellular inclusions.
The American journal of pathology 1989;134(3):505-13.
1989: M Onorato; P Mulvihill; J Connolly; P Galloway; Peter J Whitehouse; George Perry
Alteration of neuritic cytoarchitecture in Alzheimer disease.
Progress in clinical and biological research 1989;317():781-9.
1989: L Autilio-Gambetti; A Morandi; Dora M. Kovacs; Massimo Tabaton; B Schaetzle; C Hauer; R K Groger; Mark L Tykocinski; George Perry; Barry D Greenberg
Amyloid precursor protein in cell cultures: a 130 kDa polypeptide.
Progress in clinical and biological research 1989;317():985-90.
1989: Peter J Whitehouse; P Gambetti; Sami I Harik; Rajesh N. Kalaria; George Perry; S I Younkin; Massimo Tabaton; JR Unnerstall
Neurochemistry of dementia: establishing the links.
Progress in clinical and biological research 1989;317():131-42.
1989: E O Lew; B Rozdilsky; D G Munoz; George Perry
A new type of neuronal cytoplasmic inclusion: histological, ultrastructural, and immunocytochemical studies.
Acta neuropathologica 1989;77(6):599-604.
1989: George Perry; Sandra L Siedlak; P Mulvihill; M Kancherla; M Mijares; M Kawai; Pierluigi Gambetti; S Sharma; L Maggiora; J Cornette
Immunolocalization of the amyloid precursor protein within the senile plaque.
Progress in clinical and biological research 1989;317():1021-5.
1988: L Autilio-Gambetti; A Morandi; Massimo Tabaton; B Schaetzle; Dora M. Kovacs; George Perry; S Sharma; J Cornette; Barry D Greenberg; Pierluigi Gambetti
The amyloid percursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types.
FEBS letters 1988;241(1-2):94-8.
1988: Rajesh N. Kalaria; S A Gravina; J W Schmidley; George Perry; Sami I Harik
The glucose transporter of the human brain and blood-brain barrier.
Annals of neurology 1988;24(6):757-64.
1988: M Ohta; Normand Marceau; George Perry; V Manetto; Pierluigi Gambetti; L Autilio-Gambetti; J Metuzals; H Kawahara; Monique Cadrin; S W French
Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes.
Laboratory investigation; a journal of technical methods and pathology 1988;59(6):848-56.
1988: P G Galloway; Inge Grundke-Iqbal; Khalid Iqbal; George Perry
Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles.
Journal of neuropathology and experimental neurology 1988;47(6):654-63.
1988: V Manetto; N H Sternberger; George Perry; L A Sternberger; Pierluigi Gambetti
Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis.
Journal of neuropathology and experimental neurology 1988;47(6):642-53.
1988: George Perry; S Lipphardt; P Mulvihill; M Kancherla; M Mijares; P Gambetti; S Sharma; L Maggiora; J Cornette; T Lobl
Amyloid precursor protein in senile plaques of Alzheimer disease.
Lancet 1988;2(8613):746.
1988: Massimo Tabaton; Peter J Whitehouse; George Perry; Peter Davies; L Autilio-Gambetti; Pierluigi Gambetti
Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy.
Annals of neurology 1988;24(3):407-13.
1988: Massimo Tabaton; George Perry; L Autilio-Gambetti; V Manetto; Pierluigi Gambetti
Influence of neuronal location on antigenic properties of neurofibrillary tangles.
Annals of neurology 1988;23(6):604-10.
1988: V Manetto; George Perry; Massimo Tabaton; P Mulvihill; V A Fried; HT Smith; Pierluigi Gambetti; L Autilio-Gambetti
Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4501-5.
1988: Y Matsumoto; George Perry; R J Levine; R Blanton; AA Mahmoud; M Aikawa
Paramyosin and actin in schistosomal teguments.
Nature 1988;333(6168):76-8.
1988: C T Atkinson; M Aikawa; George Perry; T Fujino; V Bennett; E A Davidson; R J Howard
Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes.
European journal of cell biology 1988;45(2):192-9.
1988: George Perry; C Lambert
Arachidonic acid metabolism in Ascidia ceratodes eggs: role of lipid peroxidation.
Comparative biochemistry and physiology. B, Comparative biochemistry 1988;90(4):785-9.
1987: Y Matsumoto; George Perry; Leonard W. Scheibel; M Aikawa
Role of calmodulin in Plasmodium falciparum: implications for erythrocyte invasion by the merozoite.
European journal of cell biology 1987;45(1):36-43.
1987: George Perry; P Mulvihill; V Manetto; L Autilio-Gambetti; Pierluigi Gambetti
Immunocytochemical properties of Alzheimer straight filaments.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(11):3736-8.
1987: George Perry; R Friedman; D H Kang; V Manetto; L Autilio-Gambetti; Pierluigi Gambetti
Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions.
Brain research 1987;420(2):233-42.
1987: George Perry; D Stewart; R Friedman; V Manetto; L Autilio-Gambetti; Pierluigi Gambetti
Filaments of Pick's bodies contain altered cytoskeletal elements.
The American journal of pathology 1987;127(3):559-68.
1987: George Perry; R Friedman; G Shaw; V Chau
Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):3033-6.
1987: P G Galloway; George Perry; P Gambetti
Hirano body filaments contain actin and actin-associated proteins.
Journal of neuropathology and experimental neurology 1987;46(2):185-99.
1987: P G Galloway; George Perry; Kenneth S Kosik; P Gambetti
Hirano bodies contain tau protein.
Brain research 1987;403(2):337-40.
1986: George Perry; L Wible; B R Brinkley
Microtubules are not altered in the dystrophic chicken.
Experimental cell research 1986;163(1):266-72.
1986: George Perry; Dennis J Selkoe; B R Block; D Stewart; L Autilio-Gambetti; P Gambetti
Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.
Journal of neuropathology and experimental neurology 1986;45(2):161-8.
1986: M Kasper; R Goertchen; P Stosiek; George Perry; U Karsten
Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues.
Virchows Archiv. A, Pathological anatomy and histopathology 1986;410(3):173-7.
1985: George Perry; N Rizzuto; L Autilio-Gambetti; P Gambetti
Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(11):3916-20.
1985: George Perry; D Epel
Fertilization stimulates lipid peroxidation in the sea urchin egg.
Developmental biology 1985;107(1):58-65.
1985: George Perry; D Epel
Characterization of a Ca2+-stimulated lipid peroxidizing system in the sea urchin egg.
Developmental biology 1985;107(1):47-57.
1984: D C Anderson; B J Hughes; L J Wible; George Perry; C W Smith; B R Brinkley
Impaired motility of neonatal PMN leukocytes: relationship to abnormalities of cell orientation and assembly of microtubules in chemotactic gradients.
Journal of leukocyte biology 1984;36(1):1-15.
1983: P Gambetti; L Autilio-Gambetti; George Perry; G Shecket; R C Crane
Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions.
Laboratory investigation; a journal of technical methods and pathology 1983;49(4):430-5.
1983: R L Pardue; R C Brady; George Perry; J R Dedman
Production of monoclonal antibodies against calmodulin by in vitro immunization of spleen cells.
The Journal of cell biology 1983;96(4):1149-54.
1982: D Epel; George Perry; T Schmidt
Intracellular calcium and fertilization: role of the cation and regulation of intracellular calcium levels.
Progress in clinical and biological research 1982;91():171-83.
1981: George Perry; D Epel
Ca2+-stimulated production of H2O2 from naphthoquinone oxidation in Arbacia eggs.
Experimental cell research 1981;134(1):65-72.
1980: W Byrd; George Perry
Cytochalasin B blocks sperm incorporation but allows activation of the sea urchin egg.
Experimental cell research 1980;126(2):333-42.