Fredrik Karpe

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Christodoulides Constantinos; Dyson Pamela; Sprecher Dennis; Tsintzas Kostas; Karpe Fredrik
Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.
Karpe Fredrik; Ehrenborg Ewa E
PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function.
Ruge Toralph; Hodson Leanne; Cheeseman Jane; Dennis A Louise; Fielding Barbara A; Humphreys Sandy M; Frayn Keith N; Karpe Fredrik
Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage.

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All Publications

2009: Christodoulides Constantinos; Dyson Pamela; Sprecher Dennis; Tsintzas Kostas; Karpe Fredrik
Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.
The Journal of clinical endocrinology and metabolism 2009;94(9):3594-601.
2009: Karpe Fredrik; Ehrenborg Ewa E
PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function.
Current opinion in lipidology 2009;20(4):333-6.
2009: Ruge Toralph; Hodson Leanne; Cheeseman Jane; Dennis A Louise; Fielding Barbara A; Humphreys Sandy M; Frayn Keith N; Karpe Fredrik
Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage.
The Journal of clinical endocrinology and metabolism 2009;94(5):1781-8.
2009: Hodson Leanne; McQuaid Siobhán E; Karpe Fredrik; Frayn Keith N; Fielding Barbara A
Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.
American journal of physiology. Endocrinology and metabolism 2009;296(1):E64-71.
2009: Stimson Roland H; Andersson Jonas; Andrew Ruth; Redhead Doris N; Karpe Fredrik; Hayes Peter C; Olsson Tommy; Walker Brian R
Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.
Diabetes 2009;58(1):46-53.
2009: Funada Junichi; Betts Tim R; Hodson Leanne; Humphreys Sandy M; Timperley Jon; Frayn Keith N; Karpe Fredrik
Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling.
PloS one 2009;4(10):e7533.
2008: Tan Garry D; Savage David B; Fielding Barbara A; Collins Jenny; Hodson Leanne; Humphreys Sandy M; O'Rahilly Stephen; Chatterjee Krishna; Frayn Keith N; Karpe Fredrik
Fatty acid metabolism in patients with PPARgamma mutations.
The Journal of clinical endocrinology and metabolism 2008;93(11):4462-70.
2008: Karpe Fredrik; Hodson Leanne
Caution on the interpretation of plasma fatty acid composition as a proxy marker for SCD1 activity: particular implications for using the 16:1/16:0 ratio in QTL studies involving hyperlipidemic patients.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(8):e152; author reply e153.
2008: Bickerton A S T; Roberts R; Fielding B A; Tornqvist H; Blaak E E; Wagenmakers A J M; Gilbert M; Humphreys S M; Karpe F; Frayn K N
Adipose tissue fatty acid metabolism in insulin-resistant men.
Diabetologia 2008;51(8):1466-74.
2008: Barber T M; Bennett A J; Groves C J; Sovio U; Ruokonen A; Martikainen H; Pouta A; Hartikainen A-L; Elliott P; Lindgren C M; Freathy R M; Koch K; Ouwehand W H; Karpe F; Conway G S; Wass J A H; Järvelin M-R; Franks S; McCarthy M I
Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.
Diabetologia 2008;51(7):1153-8.
2008: Freathy Rachel M; Timpson Nicholas J; Lawlor Debbie A; Pouta Anneli; Ben-Shlomo Yoav; Ruokonen Aimo; Ebrahim Shah; Shields Beverley; Zeggini Eleftheria; Weedon Michael N; Lindgren Cecilia M; Lango Hana; Melzer David; Ferrucci Luigi; Paolisso Giuseppe; Neville Matthew J; Karpe Fredrik; Palmer Colin N A; Morris Andrew D; Elliott Paul; Jarvelin Marjo-Riitta; Smith George Davey; McCarthy Mark I; Hattersley Andrew T; Frayling Timothy M
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.
Diabetes 2008;57(5):1419-26.
2008: Roberts Rachel; Bickerton Alex S; Fielding Barbara A; Blaak Ellen E; Wagenmakers Anton J; Chong Mary F-F; Gilbert Marjorie; Karpe Fredrik; Frayn Keith N
Reduced oxidation of dietary fat after a short term high-carbohydrate diet.
The American journal of clinical nutrition 2008;87(4):824-31.
2008: Chong Mary F-F; Hodson Leanne; Bickerton Alex S; Roberts Rachel; Neville Matt; Karpe Fredrik; Frayn Keith N; Fielding Barbara A
Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding.
The American journal of clinical nutrition 2008;87(4):817-23.
2008: Barber Thomas M; Casanueva Felipe F; Karpe Fredrik; Lage Mary; Franks Stephen; McCarthy Mark I; Wass John A H
Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(4):511-6.
2008: Hofker Marten; Bernini Franco; von Eckardstein Arnold; Freeman Dilys; Heeren Joerg; Karpe Fredrik; Kalopissis Athina; Kronenberg Florian; Kuipers Folkert; Lindstedt Ken; Parini Paolo; Schuster Gertrud; van Dijk Ko Willems
European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.
Atherosclerosis 2008;197(1):471-9.
2008: Frayn K N; Langin D; Karpe F
Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased.
Diabetologia 2008;51(3):394-7.
2008: Barber Thomas M; Golding Stephen J; Alvey Christopher; Wass John A H; Karpe Fredrik; Franks Stephen; McCarthy Mark I
Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2008;93(3):999-1004.
2008: Evans Kevin; Burdge Graham C; Wootton Stephen A; Collins Jenny M; Clark Mo L; Tan Garry D; Karpe Fredrik; Frayn Keith N
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.
Atherosclerosis 2008;197(1):164-70.
2008: van Harmelen Vanessa; Eriksson Anna; Aström Gaby; Wåhlén Kerstin; Näslund Erik; Karpe Fredrik; Frayn Keith; Olsson Tommy; Andersson Jonas; Rydén Mikel; Arner Peter
Vascular peptide endothelin-1 links fat accumulation with alterations of visceral adipocyte lipolysis.
Diabetes 2008;57(2):378-86.
2008: Risérus Ulf; Sprecher Dennis; Johnson Tony; Olson Eric; Hirschberg Sandra; Liu Aixue; Fang Zeke; Hegde Priti; Richards Duncan; Sarov-Blat Leli; Strum Jay C; Basu Samar; Cheeseman Jane; Fielding Barbara A; Humphreys Sandy M; Danoff Theodore; Moore Niall R; Murgatroyd Peter; O'Rahilly Stephen; Sutton Pauline; Willson Tim; Hassall David; Frayn Keith N; Karpe Fredrik
Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.
Diabetes 2008;57(2):332-9.
2008: Savage David B; Zhai Lanmin; Ravikumar Balasubramanian; Choi Cheol Soo; Snaar Johanna E; McGuire Amanda C; Wou Sung-Eun; Medina-Gomez Gemma; Kim Sheene; Bock Cheryl B; Segvich Dyann M; Solanky Bhavana; Deelchand Dinesh; Vidal-Puig Antonio; Wareham Nicholas J; Shulman Gerald I; Karpe Fredrik; Taylor Roy; Pederson Bartholomew A; Roach Peter J; O'Rahilly Stephen; DePaoli-Roach Anna A
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
PLoS medicine 2008;5(1):e27.
2008: Goossens Gijs H; Karpe Fredrik
Human adipose tissue blood flow and micromanipulation of human subcutaneous blood flow.
Methods in molecular biology (Clifton, N.J.) 2008;456():97-107.
2007: Frayn K N; Tan G D; Karpe F
Adipose tissue: a key target for diabetes pathophysiology and treatment?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2007;39(10):739-42.
2007: Hodson Leanne; Bickerton Alex S T; McQuaid Siobhán E; Roberts Rachel; Karpe Fredrik; Frayn Keith N; Fielding Barbara A
The contribution of splanchnic fat to VLDL triglyceride is greater in insulin-resistant than insulin-sensitive men and women: studies in the postprandial state.
Diabetes 2007;56(10):2433-41.
2007: Hofker Marten; Calabresi Laura; von Eckardstein Arnold; Heeren Joerg; Karpe Fredrik; Kalopissis Athina; Kronenberg Florian; Kuipers Folkert; Lindstedt Ken; Parini Paolo; Schuster Gertrud; van Dijk Ko Willems
European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.
Atherosclerosis 2007;193(2):461-8.
2007: Karpe F; Bickerton A S; Hodson L; Fielding B A; Tan G D; Frayn K N
Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation.
Biochemical Society transactions 2007;35(Pt 3):472-6.
2007: Wake Deborah J; Stimson Roland H; Tan Garry D; Homer Natalie Z M; Andrew Ruth; Karpe Fredrik; Walker Brian R
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.
The Journal of clinical endocrinology and metabolism 2007;92(5):1848-56.
2007: Cadoudal T; Blouin J M; Collinet M; Fouque F; Tan G D; Loizon E; Beale E G; Frayn K N; Karpe F; Vidal H; Benelli C; Forest C
Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.
Diabetologia 2007;50(3):666-75.
2007: Heath Richard B; Karpe Fredrik; Milne Ross W; Burdge Graham C; Wootton Stephen A; Frayn Keith N
Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state.
American journal of physiology. Endocrinology and metabolism 2007;292(3):E732-9.
2007: Neville Matt J; Clarke Robert; Evans John Grimley; Rubinsztein David C; Karpe Fredrik
Absence of relationship between MTTP haplotypes and longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(2):202-5.
2007: Bickerton Alex S T; Roberts Rachel; Fielding Barbara A; Hodson Leanne; Blaak Ellen E; Wagenmakers Anton J M; Gilbert Marjorie; Karpe Fredrik; Frayn Keith N
Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period.
Diabetes 2007;56(1):168-76.
2007: Tahiri Youssef; Karpe Fredrik; Tan Garry D; Cianflone Katherine
Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics.
Nutrition & metabolism 2007;4():11.
2006: Tan G D; Olivecrona G; Vidal H; Frayn K N; Karpe F
Insulin sensitisation affects lipoprotein lipase transport in type 2 diabetes: role of adipose tissue and skeletal muscle in response to rosiglitazone.
Diabetologia 2006;49(10):2412-8.
2006: Lundahl Björn; Skoglund-Andersson Camilla; Caslake Muriel; Bedford Dorothy; Stewart Philip; Hamsten Anders; Packard Christopher J; Karpe Fredrik
Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles.
American journal of physiology. Endocrinology and metabolism 2006;290(4):E739-45.
2006: Goossens G H; McQuaid S E; Dennis A L; van Baak M A; Blaak E E; Frayn K N; Saris W H M; Karpe F
Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.
The Journal of physiology 2006;571(Pt 2):451-60.
2006: Tan G D; Neville M J; Liverani E; Humphreys S M; Currie J M; Dennis L; Fielding B A; Karpe F
The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.
Diabetologia 2006;49(1):158-68.
2005: Karpe F; Tan G D
Adipose tissue function in the insulin-resistance syndrome.
Biochemical Society transactions 2005;33(Pt 5):1045-8.
2005: Tan G D; Debard C; Funahashi T; Humphreys S M; Matsuzawa Y; Frayn K N; Karpe F; Vidal H
Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy.
Diabetologia 2005;48(8):1585-9.
2005: Frayn Keith N; Fielding Barbara A; Karpe Fredrik
Adipose tissue fatty acid metabolism and cardiovascular disease.
Current opinion in lipidology 2005;16(4):409-15.
2005: Risérus Ulf; Tan Garry D; Fielding Barbara A; Neville Matt J; Currie Jenny; Savage David B; Chatterjee V Krishna; Frayn Keith N; O'Rahilly Stephen; Karpe Fredrik
Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma.
Diabetes 2005;54(5):1379-84.
2005: Karpe Fredrik; Fielding Barbara A; Coppack Simon W; Lawrence Victor J; Macdonald Ian A; Frayn Keith N
Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo.
Diabetes 2005;54(5):1297-303.
2005: Tan G D; Fielding B A; Currie J M; Humphreys S M; Désage M; Frayn K N; Laville M; Vidal H; Karpe F
The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes.
Diabetologia 2005;48(1):83-95.
2004: Karpe Fredrik; Frayn Keith N
The nicotinic acid receptor--a new mechanism for an old drug.
Lancet 2004;363(9424):1892-4.
2004: Ledmyr Helena; McMahon Alex D; Ehrenborg Ewa; Nielsen Lars B; Neville Matt; Lithell Hans; MacFarlane Peter W; Packard Christopher J; Karpe Fredrik;
The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.
Circulation 2004;109(19):2279-84.
2004: Frayn Keith N; Ardilouze Jean-Luc; Fielding Barbara A; Karpe Fredrik
Coupling of metabolism and cardiovascular responses.
Clinical science (London, England : 1979) 2004;106(5):547-8.
2004: Hofker M; Calabresi L; Jauhiainen M; Nimpf J; Rudling M; Talmud P; Mooser V; Dallinga-Thie G; von Eckardstein A; Staels B; Karpe F; Kuipers F
European Lipoprotein Club: report of the 26th ELC Annual Conference, Tutzing, 8-11 September 2003.
Atherosclerosis 2004;173(1):125-34.
2004: Ardilouze J-L; Karpe F; Currie J M; Frayn K N; Fielding B A
Subcutaneous adipose tissue blood flow varies between superior and inferior levels of the anterior abdominal wall.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(2):228-33.
2004: Tan Garry D; Goossens Gijs H; Humphreys Sandy M; Vidal Hubert; Karpe Fredrik
Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans.
Obesity research 2004;12(1):114-8.
2004: Ardilouze Jean-Luc; Fielding Barbara A; Currie Jenny M; Frayn Keith N; Karpe Fredrik
Nitric oxide and beta-adrenergic stimulation are major regulators of preprandial and postprandial subcutaneous adipose tissue blood flow in humans.
Circulation 2004;109(1):47-52.
2003: Skogsberg J; McMahon A D; Karpe F; Hamsten A; Packard C J; Ehrenborg E;
Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.
Journal of internal medicine 2003;254(6):597-604.
2003: Heath Richard B; Karpe Fredrik; Milne Ross W; Burdge Graham C; Wootton Stephen A; Frayn Keith N
Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period.
Journal of lipid research 2003;44(11):2065-72.
2003: Koutsari C; Karpe F; Humphreys S M; Frayn K N; Hardman A E
Plasma leptin is influenced by diet composition and exercise.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(8):901-6.
2003: Frayn K N; Karpe F; Fielding B A; Macdonald I A; Coppack S W
Integrative physiology of human adipose tissue.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(8):875-88.
2003: Tan Garry D; Debard Cyrille; Tiraby Claire; Humphreys Sandy M; Frayn Keith N; Langin Dominique; Vidal Hubert; Karpe Fredrik
A "futile cycle" induced by thiazolidinediones in human adipose tissue?
Nature medicine 2003;9(7):811-2; author reply 812.
2003: Skoglund-Andersson Camilla; Ehrenborg Ewa; Fisher Rachel M; Olivecrona Gunilla; Hamsten Anders; Karpe Fredrik
Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.
Atherosclerosis 2003;167(2):311-7.
2003: Savage David B; Tan Garry D; Acerini Carlo L; Jebb Susan A; Agostini Maura; Gurnell Mark; Williams Rachel L; Umpleby A Margot; Thomas E Louise; Bell Jimmy D; Dixon Adrian K; Dunne Fidelma; Boiani Romina; Cinti Saverio; Vidal-Puig Antonio; Karpe Fredrik; Chatterjee V Krishna K; O'Rahilly Stephen
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.
Diabetes 2003;52(4):910-7.
2003: Huxley R R; Hawkins M H; Humphries S E; Karpe F; Neil H A W;
Risk of fatal stroke in patients with treated familial hypercholesterolemia: a prospective registry study.
Stroke; a journal of cerebral circulation 2003;34(1):22-5.
2003: Skoglund-Andersson C; Karpe F; Hellénius M-L; Regnström J; Hamsten A; Tornvall P
In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins.
European journal of clinical investigation 2003;33(1):51-7.
2003: Beysen Carine; Belcher Abigail K; Karpe Fredrik; Fielding Barbara A; Herrera Emilio; Frayn Keith N
Novel experimental protocol to increase specific plasma nonesterified fatty acids in humans.
American journal of physiology. Endocrinology and metabolism 2003;284(1):E18-24.
2002: Beysen C; Karpe F; Fielding B A; Clark A; Levy J C; Frayn K N
Interaction between specific fatty acids, GLP-1 and insulin secretion in humans.
Diabetologia 2002;45(11):1533-41.
2002: Ulahannan T J; Karpe F; Humphreys S M; Matthews D R; Frayn K N
Effects of acute administration of doxazosin on fasting and postprandial haemodynamics and lipid metabolism in healthy subjects.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(9):499-503.
2002: Björkegren Johan; Silveira Angela; Boquist Susanna; Tang Rong; Karpe Fredrik; Bond M Gene; de Faire Ulf; Hamsten Anders
Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(9):1470-4.
2002: Karpe Fredrik; Fielding Barbara A; Ilic Vera; Macdonald Ian A; Summers Lucinda K M; Frayn Keith N
Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity.
Diabetes 2002;51(8):2467-73.
2002: Karpe Fredrik
Postprandial lipemia--effect of lipid-lowering drugs.
Atherosclerosis. Supplements 2002;3(1):41-6.
2002: Karpe Fredrik; Fielding Barbara A; Ardilouze Jean-Luc; Ilic Vera; Macdonald Ian A; Frayn Keith N
Effects of insulin on adipose tissue blood flow in man.
The Journal of physiology 2002;540(Pt 3):1087-93.
2002: Boquist Susanna; Karpe Fredrik; Danell-Toverud Karin; Hamsten Anders
Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia.
Atherosclerosis 2002;162(1):163-70.
2002: Skoog T; Dichtl W; Boquist S; Skoglund-Andersson C; Karpe F; Tang R; Bond M G; de Faire U; Nilsson J; Eriksson P; Hamsten A
Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men.
European heart journal 2002;23(5):376-83.
2002: Lundahl Björn; Hamsten Anders; Karpe Fredrik
Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):289-93.
2002: Ledmyr Helena; Karpe Fredrik; Lundahl Björn; McKinnon Margaret; Skoglund-Andersson Camilla; Ehrenborg Ewa
Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.
Journal of lipid research 2002;43(1):51-8.
2002: Karpe F; Fielding B A; Ilic V; Humphreys S M; Frayn K N
Monitoring adipose tissue blood flow in man: a comparison between the (133)xenon washout method and microdialysis.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2002;26(1):1-5.
2001: Koutsari C; Karpe F; Humphreys S M; Frayn K N; Hardman A E
Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(9):1520-5.
2001: Karpe F; Taskinen M R; Nieminen M S; Frick M H; Kesäniemi Y A; Pasternack A; Hamsten A; Syvänne M
Remnant-like lipoprotein particle cholesterol concentration and progression of coronary and vein-graft atherosclerosis in response to gemfibrozil treatment.
Atherosclerosis 2001;157(1):181-7.
2001: Karpe F; Boquist S; Tang R; Bond G M; de Faire U; Hamsten A
Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides.
Journal of lipid research 2001;42(1):17-21.
2000: Björn Lundahl; Leren T P; Ose L; Hamsten A; Karpe F
A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(7):1784-8.
2000: van't Hooft F M; Lundahl B; Ragogna F; Karpe F; Olivecrona G; Hamsten A
Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(5):1335-9.
2000: Boquist S; Hamsten A; Karpe F; Ruotolo G
Insulin and non-esterified fatty acid relations to alimentary lipaemia and plasma concentrations of postprandial triglyceride-rich lipoproteins in healthy middle-aged men.
Diabetologia 2000;43(2):185-93.
1999: Karpe F
Postprandial lipoprotein metabolism and atherosclerosis.
Journal of internal medicine 1999;246(4):341-55.
1999: Skoglund-Andersson C; Tang R; Bond M G; de Faire U; Hamsten A; Karpe F
LDL particle size distribution is associated with carotid intima-media thickness in healthy 50-year-old men.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(10):2422-30.
1999: Boquist S; Ruotolo G; Tang R; Björkegren J; Bond M G; de Faire U; Karpe F; Hamsten A
Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men.
Circulation 1999;100(7):723-8.
1999: Allison B A; Nilsson L; Karpe F; Hamsten A; Eriksson P
Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1354-60.
1999: Karpe F; Hellénius M L; Hamsten A
Differences in postprandial concentrations of very-low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease.
Metabolism: clinical and experimental 1999;48(3):301-7.
1998: Karpe F; de Faire U; Mercuri M; Bond M G; Hellénius M L; Hamsten A
Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men.
Atherosclerosis 1998;141(2):307-14.
1998: Karpe F; Olivecrona T; Olivecrona G; Samra J S; Summers L K; Humphreys S M; Frayn K N
Lipoprotein lipase transport in plasma: role of muscle and adipose tissues in regulation of plasma lipoprotein lipase concentrations.
Journal of lipid research 1998;39(12):2387-93.
1998: Ruotolo G; Ericsson C G; Tettamanti C; Karpe F; Grip L; Svane B; Nilsson J; de Faire U; Hamsten A
Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT).
Journal of the American College of Cardiology 1998;32(6):1648-56.
1998: Björkegren J; Karpe F; Milne R W; Hamsten A
Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma.
Journal of lipid research 1998;39(7):1412-20.
1998: Karpe F; Lundahl B; Ehrenborg E; Eriksson P; Hamsten A
A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(5):756-61.
1998: Boquist S; Ruotolo G; Hellénius M L; Danell-Toverud K; Karpe F; Hamsten A
Effects of a cardioselective beta-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk.
Atherosclerosis 1998;137(2):391-400.
1998: Björkegren J; Karpe F; Vitols S; Tornvall P; Hamsten A
Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro.
Journal of lipid research 1998;39(2):423-36.
1998: Eriksson P; Nilsson L; Karpe F; Hamsten A
Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(1):20-6.
1997: Karpe F; Humphreys S M; Samra J S; Summers L K; Frayn K N
Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans.
Journal of lipid research 1997;38(11):2335-43.
1997: Karpe F
Mechanisms of postprandial hyperlipidaemia--remnants and coronary artery disease.
Diabetic medicine : a journal of the British Diabetic Association 1997;14 Suppl 3():S60-6.
1997: Karpe F
Postprandial lipid metabolism in relation to coronary heart disease.
The Proceedings of the Nutrition Society 1997;56(2):671-8.
1997: Karpe F; Olivecrona T; Hamsten A; Hultin M
Chylomicron/chylomicron remnant turnover in humans: evidence for margination of chylomicrons and poor conversion of larger to smaller chylomicron remnants.
Journal of lipid research 1997;38(5):949-61.
1997: Björkegren J; Hamsten A; Milne R W; Karpe F
Alterations of VLDL composition during alimentary lipemia.
Journal of lipid research 1997;38(2):301-14.
1996: Tornvall P; Karpe F; Proudler A; Båvenholm P; Landou C; Olivecrona T; Hamsten A
High-density lipoprotein: relations to metabolic parameters and severity of coronary artery disease.
Metabolism: clinical and experimental 1996;45(11):1375-82.
1996: Silveira A; Karpe F; Johnsson H; Bauer K A; Hamsten A
In vivo demonstration in humans that large postprandial triglyceride-rich lipoproteins activate coagulation factor VII through the intrinsic coagulation pathway.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(11):1333-9.
1996: Fatah K; Silveira A; Tornvall P; Karpe F; Blombäck M; Hamsten A
Proneness to formation of tight and rigid fibrin gel structures in men with myocardial infarction at a young age.
Thrombosis and haemostasis 1996;76(4):535-40.
1996: Tornvall P; Båvenholm P; Hellénius M L; Karpe F; Regnström J; de Faire U
A decrease in cardiovascular risk factors in healthy 40-year-old Swedish men between 1980-1983 and 1991-1992.
Journal of cardiovascular risk 1996;3(4):379-83.
1996: Bjorkegren J; Packard C J; Hamsten A; Bedford D; Caslake M; Foster L; Shepherd J; Stewart P; Karpe F
Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.
Journal of lipid research 1996;37(1):76-86.
1996: Karpe F; Hamsten A; Uffelman K; Steiner G
Apolipoprotein B-48.
Methods in enzymology 1996;263():95-104.
1995: Båvenholm P; Karpe F; Proudler A; Tornvall P; Crook D; Hamsten A
Association of insulin and insulin propeptides with an atherogenic lipoprotein phenotype.
Metabolism: clinical and experimental 1995;44(11):1481-8.
1995: Tornvall P; Olivecrona G; Karpe F; Hamsten A; Olivecrona T
Lipoprotein lipase mass and activity in plasma and their increase after heparin are separate parameters with different relations to plasma lipoproteins.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(8):1086-93.
1995: Karpe F; Hultin M
Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway.
Journal of lipid research 1995;36(7):1557-66.
1995: Karpe F; Hamsten A
Postprandial lipoprotein metabolism and atherosclerosis.
Current opinion in lipidology 1995;6(3):123-9.
1995: Karpe F; Bell M; Björkegren J; Hamsten A
Quantification of postprandial triglyceride-rich lipoproteins in healthy men by retinyl ester labeling and simultaneous measurement of apolipoproteins B-48 and B-100.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(2):199-207.
1994: Silveira A; Green F; Karpe F; Blombäck M; Humphries S; Hamsten A
Elevated levels of factor VII activity in the postprandial state: effect of the factor VII Arg-Gln polymorphism.
Thrombosis and haemostasis 1994;72(5):734-9.
1994: Hamsten A; Eriksson P; Karpe F; Silveira A
Relationships of thrombosis and fibrinolysis to atherosclerosis.
Current opinion in lipidology 1994;5(5):382-9.
1994: Karpe F; Hamsten A
Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE.
Journal of lipid research 1994;35(7):1311-7.
1994: Moor E; Hamsten A; Karpe F; Båvenholm P; Blombäck M; Silveira A
Relationship of tissue factor pathway inhibitor activity to plasma lipoproteins and myocardial infarction at a young age.
Thrombosis and haemostasis 1994;71(6):707-12.
1994: Karpe F; Steiner G; Uffelman K; Olivecrona T; Hamsten A
Postprandial lipoproteins and progression of coronary atherosclerosis.
Atherosclerosis 1994;106(1):83-97.
1994: Silveira A; Karpe F; Blombäck M; Steiner G; Walldius G; Hamsten A
Activation of coagulation factor VII during alimentary lipemia.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(1):60-9.
1994: Hamsten A; Karpe F; Båvenholm P; Silveira A
Interactions amongst insulin, lipoproteins and haemostatic function relevant to coronary heart disease.
Journal of internal medicine. Supplement 1994;736():75-88.
1993: Karpe F; Steiner G; Olivecrona T; Carlson L A; Hamsten A
Metabolism of triglyceride-rich lipoproteins during alimentary lipemia.
The Journal of clinical investigation 1993;91(3):748-58.
1993: Karpe F; Tornvall P; Olivecrona T; Steiner G; Carlson L A; Hamsten A
Composition of human low density lipoprotein: effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein.
Atherosclerosis 1993;98(1):33-49.
1993: Karpe F; Bard J M; Steiner G; Carlson L A; Fruchart J C; Hamsten A
HDLs and alimentary lipemia. Studies in men with previous myocardial infarction at a young age.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(1):11-22.
1991: Tornvall P; Karpe F; Carlson L A; Hamsten A
Relationships of low density lipoprotein subfractions to angiographically defined coronary artery disease in young survivors of myocardial infarction.
Atherosclerosis 1991;90(1):67-80.
1991: Karpe F; Regnström J; Tornvall P
[Can cholesterol lowering treatment have unwanted effects?]
Läkartidningen 1991;88(18):1670-1.
1990: Karpe F; Johansson J; Carlson L A
Studies on the lecithin: cholesterol acyltransferase substrate properties of HDL as determined by its subclass distribution analysed by gradient gel electrophoresis.
Biochimica et biophysica acta 1990;1042(3):310-4.
1988: Karpe F; Regnström J; Tornvall P
[Low cholesterol level--symptom of a disease?]
Läkartidningen 1988;85(52):4609.

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