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Lucio Cocco

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William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Richard A Franklin; Michelle M LaHair; Alberto M Martelli; Kristin M Stadelman; Linda S Steelman; Steven L Abrams; James A McCubrey
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment.
Matilde Y Follo; Pietro Gobbi; Francesco A Manzoli; Sandra Marmiroli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Carlo Finelli; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C β1 signaling, epigenetics and treatments in MDS.
Matilde Y Follo; Lucia Manzoli; Alberto M Martelli; giovanni martinelli; S Mongiorgi; S Paolini; C Clissa; Carlo Finelli; G Fioravanti; Lucio Cocco
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients.

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2013: William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Richard A Franklin; Michelle M LaHair; Alberto M Martelli; Kristin M Stadelman; Linda S Steelman; Steven L Abrams; James A McCubrey
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment.
Advances in biological regulation 2013;53(1):146-55.
2013: Matilde Y Follo; Pietro Gobbi; Francesco A Manzoli; Sandra Marmiroli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Carlo Finelli; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C β1 signaling, epigenetics and treatments in MDS.
Advances in biological regulation 2013;53(1):2-7.
2012: Matilde Y Follo; Lucia Manzoli; Alberto M Martelli; giovanni martinelli; S Mongiorgi; S Paolini; C Clissa; Carlo Finelli; G Fioravanti; Lucio Cocco
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients.
Leukemia 2012;26(12):2474-82.
2012: James A McCubrey; Sanja Mijatovic; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Linda Steelman; Agostino Tafuri; Maria Clorinda Mazzarino; Steven L Abrams; Jörg Bäsecke; Saverio Candido; Melchiorre Cervello; William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Paolo Fagone; Richard A Franklin; Massimo Libra; Danijela Maksimovic-Ivanic; Grazia Malaponte; Alberto M Martelli
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.
Oncotarget 2012;3(10):1068-111.
2012: James A McCubrey; Sanja Mijatovic; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Linda Steelman; Agostino Tafuri; Maria Clorinda Mazzarino; Steven L Abrams; Jörg Bäsecke; Saverio Candido; Melchiorre Cervello; William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Paolo Fagone; Massimo Libra; Danijela Maksimovic-Ivanic; Grazia Malaponte; Alberto M Martelli
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.
Oncotarget 2012;3(9):954-87.
2012: Irene Faenza; Roberta Fiume; Stephaniè Pacella; Manuela Piazzi; Benedikt Schoser; Alberto Bavelloni; William Blalock; Antonietta D'Angelo; Lucio Cocco
A role for PLCβ1 in myotonic dystrophies type 1 and 2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(7):3042-8.
2012: Matilde Y Follo; marco gobbi; Lucia Manzoli; Alberto M Martelli; S Mongiorgi; M Piazzi; D Russo; C Clissa; C Colombi; C Filì; Carlo Finelli; Lucio Cocco
Epigenetic regulation of nuclear PI-PLCbeta1 signaling pathway in low-risk MDS patients during azacitidine treatment.
Leukemia 2012;26(5):943-50.
2012: Sara Mongiorgi; Giulia Ramazzotti; Cristina Clissa; Carlo Finelli; Milena Fini; Roberta Fiume; Matilde Y Follo; Roberto Giardino; Lucia Manzoli; Lucio Cocco
Nuclear PI-PLC β1 and Myelodysplastic syndromes: from bench to clinics.
Current topics in microbiology and immunology 2012;362():235-45.
2012: Lucio Cocco
The Symposium. Foreword.
Advances in biological regulation 2012;52(1):vii.
2012: Lucio Cocco
Volume 52 of the Journal. Editorial.
Advances in biological regulation 2012;52(1):ix.
2012: James A McCubrey; Sanja Mijatovic; Negin Misaghian; Giuseppeo Montalto; Ferdinando Nicoletti; Linda Steelman; Francac Stivala; Steven L Abrams; Jorg Basecke; Antonio Bonati; Melchiorre Cervello; William H Chappell; Lucio Cocco; Camilla Evangelisti; Piotr Laidler; Massimo Libra; Giovanni Ligresti; Danijela Maksimovic-Ivanic; Alberto M Martelli
Targeting the cancer initiating cell: the ultimate target for cancer therapy.
Current pharmaceutical design 2012;18(13):1784-95.
2012: Roberta Fiume; Matilde Y Follo; David R Jones; Willem Jan Keune; Alberto M Martelli; Giulia Ramazzotti; Lilly Somner; Yvette Bultsma; Nullin Divecha; Irene Faenza; Lucio Cocco
Nuclear phosphoinositides: location, regulation and function.
Sub-cellular biochemistry 2012;59():335-61.
2012: Matilde Y Follo; Alberto M Martelli; James A McCubrey; Sara Mongiorgi; Manuela Piazzi; Giulia Ramazzotti; Patrizia Santi; Irene Faenza; Carlo Finelli; Lucio Cocco
Nuclear PI-PLCβ1 and myelodysplastic syndromes: genetics and epigenetics.
Current pharmaceutical design 2012;18(13):1751-4.
2012: Matilde Y Follo; Francesco Antonio Manzoli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Roberta Fiume; Lucio Cocco
Revisiting nuclear phospholipase C signalling in MDS.
Advances in biological regulation 2012;52(1):2-6.
2012: James A McCubrey; Kazuo Umezawa; Steven L Abrams; William H Chappell; Lucio Cocco; Richard A Franklin; Alberto M Martelli; Linda S Steelman
Novel approaches to target cancer initiating cells-eliminating the root of the cancer.
Advances in biological regulation 2012;52(1):249-64.
2011: Alberto M Martelli; James A McCubrey; Andrea Ognibene; Milena Fini; Kaoru Goto; Daniela Bressanin; Francesca Buontempo; Lucio Cocco; Camilla Evangelisti
Nuclear phosphoinositides and their roles in cell biology and disease.
Critical reviews in biochemistry and molecular biology 2011;46(5):436-57.
2011: Vittoria Cenni; Lucio Cocco; Giovanna Lattanzi; Lucia Manzoli; Nadir M Maraldi; Alberto Bavelloni; Francesca Beretti; Francesca Tagliavini; Sandra Marmiroli
Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2).
Molecular biology of the cell 2011;22(16):2946-56.
2011: Camilla Evangelisti; Francesca Ricci; Pier Luigi Tazzari; Francesca Chiarini; Michela Battistelli; Elisabetta Falcieri; Andrea Ognibene; Pasqualepaolo Pagliaro; Lucio Cocco; James A McCubrey; Alberto M Martelli
Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia.
Journal of cellular physiology 2011;226(3):822-31.
2011: Matilde Y Follo; Carlo Finelli; S Mongiorgi; C Clissa; Francesca Chiarini; Giulia Ramazzotti; S Paolini; giovanni martinelli; Alberto M Martelli; Lucio Cocco
Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes.
Leukemia 2011;25(2):271-80.
2011: W L Blalock; Alberto Bavelloni; M Piazzi; F Tagliavini; Irene Faenza; Alberto M Martelli; Matilde Y Follo; Lucio Cocco
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.
Leukemia 2011;25(2):236-45.
2011: Giulia Ramazzotti; Irene Faenza; Milena Fini; Roberta Fiume; Matilde Y Follo; Roberto Giardino; Manuela Piazzi; Lucio Cocco
Nuclear phospholipase C in biological control and cancer.
Critical reviews in eukaryotic gene expression 2011;21(3):291-301.
2011: Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Camilla Evangelisti; Milena Fini; M Y Follo; Roberto Giardino; Lamberto Manzoli; Lucio Cocco
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells.
Current medicinal chemistry 2011;18(18):2715-26.
2011: Lucio Cocco; Matilde Y Follo; Irene Faenza; Roberta Fiume; Giulia Ramazzotti; George Weber; Alberto M Martelli; Francesco Antonio Manzoli
Physiology and pathology of nuclear phospholipase C β1.
Advances in enzyme regulation 2011;51(1):2-12.
2011: Giulia Ramazzotti; Irene Faenza; Roberta Fiume; Alessandro Matteucci; Manuela Piazzi; Matilde Yung Follo; Lucio Cocco
The physiology and pathology of inositide signaling in the nucleus.
Journal of cellular physiology 2011;226(1):14-20.
2010: Manuela Piazzi; Alberto Bavelloni; Irene Faenza; William Blalock; Andrea Urbani; Simona D'Aguanno; Roberta Fiume; Giulia Ramazzotti; Nadir Mario Maraldi; Lucio Cocco
eEF1A phosphorylation in the nucleus of insulin-stimulated C2C12 myoblasts: Ser⁵³ is a novel substrate for protein kinase C βI.
Molecular & cellular proteomics : MCP 2010;9(12):2719-28.
2010: Giuliana Gobbi; Elena Masselli; Cristina Micheloni; Antonio Nouvenne; Domenico Russo; Patrizia Santi; Alessandro Matteucci; Lucio Cocco; Marco Vitale; Prisco Mirandola
Hypoxia-induced down-modulation of PKCepsilon promotes trail-mediated apoptosis of tumor cells.
International journal of oncology 2010;37(3):719-29.
2010: Vincenza Rita Lo Vasco; Cinzia Fabrizi; Barbara Panetta; Lorenzo Fumagalli; Lucio Cocco
Expression pattern and sub-cellular distribution of phosphoinositide specific phospholipase C enzymes after treatment with U-73122 in rat astrocytoma cells.
Journal of cellular biochemistry 2010;110(4):1005-12.
2010: William L Blalock; Alberto Bavelloni; Manuela Piazzi; Irene Faenza; Lucio Cocco
A role for PKR in hematologic malignancies.
Journal of cellular physiology 2010;223(3):572-91.
2010: Matilde Y Follo; Sara Mongiorgi; Carlo Finelli; Cristina Clissa; Giulia Ramazzotti; Roberta Fiume; Irene Faenza; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Nuclear inositide signaling in myelodysplastic syndromes.
Journal of cellular biochemistry 2010;109(6):1065-71.
2010: Vincenza Rita Lo Vasco; Cinzia Fabrizi; Lorenzo Fumagalli; Lucio Cocco
Expression of phosphoinositide-specific phospholipase C isoenzymes in cultured astrocytes activated after stimulation with lipopolysaccharide.
Journal of cellular biochemistry 2010;109(5):1006-12.
2010: Gian Carlo Gaboardi; Giulia Ramazzotti; Alberto Bavelloni; Manuela Piazzi; Roberta Fiume; Anna Maria Billi; Alessandro Matteucci; Irene Faenza; Lucio Cocco
A role for PKCepsilon during C2C12 myogenic differentiation.
Cellular signalling 2010;22(4):629-35.
2010: Valeria Bertagnolo; Silvia Grassilli; Simona D'Aguanno; Federica Brugnoli; Alberto Bavelloni; Irene Faenza; Ervin Nika; Andrea Urbani; Lucio Cocco; Silvano Capitani
Mass spectrometry-based identification of Y745 of Vav1 as a tyrosine residue crucial in maturation of acute promyelocytic leukemia-derived cells.
Journal of proteome research 2010;9(2):752-60.
2010: Roberta Fiume; Gabriella Teti; Irene Faenza; Lucio Cocco
Phosphoinositide-specific phospholipase C beta1 signal transduction in the nucleus.
Methods in molecular biology (Clifton, N.J.) 2010;645():143-64.
2010: Lucio Cocco; Matilde Y Follo; Irene Faenza; Anna Maria Billi; Giulia Ramazzotti; Alberto M Martelli; Lucia Manzoli; George Weber
Inositide signaling in the nucleus: from physiology to pathology.
Advances in enzyme regulation 2010;50(1):2-11.
2009: William L Blalock; Cecilia Grimaldi; Federica Fala; Matilde Follo; Stefan Horn; Jorg Basecke; Giovanni Martinelli; Lucio Cocco; Alberto M Martelli
PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation.
Journal of cellular physiology 2009;221(1):232-41.
2009: Matilde Y Follo; Carlo Finelli; Sara Mongiorgi; Cristina Clissa; Costanza Bosi; Nicoletta Testoni; Francesca Chiarini; Giulia Ramazzotti; Michele Baccarani; Alberto M Martelli; Lucia Manzoli; Giovanni Martinelli; Lucio Cocco
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16811-6.
2009: Lisa Bregoli; Francesca Chiarini; Andrea Gambarelli; Gianluca Sighinolfi; Antonietta M Gatti; Patrizia Santi; Alberto M Martelli; Lucio Cocco
Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines.
Toxicology 2009;262(2):121-9.
2009: Simon J O'Carroll; Murray D Mitchell; Irene Faenza; Lucio Cocco; R Stewart Gilmour
Nuclear PLCbeta1 is required for 3T3-L1 adipocyte differentiation and regulates expression of the cyclin D3-cdk4 complex.
Cellular signalling 2009;21(6):926-35.
2009: Roberta Fiume; Giulia Ramazzotti; Gabriella Teti; Francesca Chiarini; Irene Faenza; Giovanni Mazzotti; Anna Maria Billi; Lucio Cocco
Involvement of nuclear PLCbeta1 in lamin B1 phosphorylation and G2/M cell cycle progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(3):957-66.
2009: Matilde Y Follo; Carlo Finelli; Cristina Clissa; Sara Mongiorgi; Costanza Bosi; giovanni martinelli; Michele Baccarani; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Phosphoinositide-phospholipase C beta1 mono-allelic deletion is associated with myelodysplastic syndromes evolution into acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(5):782-90.
2009: Lucio Cocco; Irene Faenza; Matilde Y Follo; Anna Maria Billi; Giulia Ramazzotti; Veronica Papa; Alberto M Martelli; Lucia Manzoli
Nuclear inositides: PI-PLC signaling in cell growth, differentiation and pathology.
Advances in enzyme regulation 2009;49(1):2-10.
2008: Pier Luigi Tazzari; Giovanna Tabellini; Francesca Ricci; Veronica Papa; Roberta Bortul; Francesca Chiarini; Camilla Evangelisti; giovanni martinelli; Andrea Bontadini; Lucio Cocco; James A McCubrey; Alberto M Martelli
Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
Cancer research 2008;68(22):9394-403.
2008: Giulia Ramazzotti; Irene Faenza; Gian Carlo Gaboardi; Manuela Piazzi; Alberto Bavelloni; Roberta Fiume; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Catalytic activity of nuclear PLC-beta(1) is required for its signalling function during C2C12 differentiation.
Cellular signalling 2008;20(11):2013-21.
2008: Federica Falà; William L Blalock; Pier Luigi Tazzari; Alessandra Cappellini; Francesca Chiarini; giovanni martinelli; Agostino Tafuri; James A McCubrey; Lucio Cocco; Alberto M Martelli
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Molecular pharmacology 2008;74(3):884-95.
2008: Giuliana Gobbi; Prisco Mirandola; Chiara Malinverno; Ivonne Sponzilli; Cecilia Carubbi; Francesca Ricci; Roberto Binazzi; Giuseppe Basso; Gabriella Giuliani-Piccari; Giulia Ramazzotti; Guido Pasquantonio; Lucio Cocco; Marco Vitale
Aberrant expression of B203.13 antigen in acute lymphoid leukemia of B-cell origin.
International journal of oncology 2008;33(2):371-4.
2008: Lucio Cocco; Irene Faenza; Matilde Y Follo; Giulia Ramazzotti; Gian Carlo Gaboardi; Anna Maria Billi; Alberto M Martelli; Lucia Manzoli
Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes.
Advances in enzyme regulation 2008;48():2-9.
2008: Irene Faenza; Lisa Bregoli; Giulia Ramazzotti; Gian Carlo Gaboardi; Matilde Y Follo; Sara Mongiorgi; Anna Maria Billi; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Nuclear phospholipase C beta1 and cellular differentiation.
Frontiers in bioscience : a journal and virtual library 2008;13():2452-63.
2008: Matilde Y Follo; Carlo Finelli; Costanza Bosi; giovanni martinelli; S Mongiorgi; Michele Baccarani; Lucia Manzoli; W L Blalock; Alberto M Martelli; Lucio Cocco
PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes.
Leukemia 2008;22(1):198-200.
2007: Camilla Evangelisti; Pier Luigi Tazzari; Massimo Riccio; Roberta Fiume; Yasukazu Hozumi; Federica Falà; Kaoru Goto; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3297-307.
2007: Giuliana Gobbi; Prisco Mirandola; Ivonne Sponzilli; Cristina Micheloni; Chiara Malinverno; Lucio Cocco; Marco Vitale
Timing and expression level of protein kinase C epsilon regulate the megakaryocytic differentiation of human CD34 cells.
Stem cells (Dayton, Ohio) 2007;25(9):2322-9.
2007: Matilde Y Follo; Sara Mongiorgi; Costanza Bosi; Alessandra Cappellini; Carlo Finelli; Francesca Chiarini; Veronica Papa; Massimo Libra; giovanni martinelli; Lucio Cocco; Alberto M Martelli
The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
Cancer research 2007;67(9):4287-94.
2007: Loris Zamai; Cristina Ponti; Prisco Mirandola; Giuliana Gobbi; Stefano Papa; Laura Galeotti; Lucio Cocco; Marco Vitale
NK cells and cancer.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4011-6.
2007: Pier Luigi Tazzari; Alessandra Cappellini; Francesca Ricci; Camilla Evangelisti; Veronica Papa; Tiziana Grafone; giovanni martinelli; Roberto Conte; Lucio Cocco; JA McCubrey; Alberto M Martelli
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Leukemia 2007;21(3):427-38.
2007: Irene Faenza; Giulia Ramazzotti; Alberto Bavelloni; Roberta Fiume; Gian Carlo Gaboardi; Matilde Y Follo; R Stewart Gilmour; Alberto M Martelli; Katya Ravid; Lucio Cocco
Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter.
Endocrinology 2007;148(3):1108-17.
2007: Vincenza Rita Lo Vasco; Cinzia Fabrizi; Marino Artico; Lucio Cocco; Anna Maria Billi; Lorenzo Fumagalli; Francesco Antonio Manzoli
Expression of phosphoinositide-specific phospholipase C isoenzymes in cultured astrocytes.
Journal of cellular biochemistry 2007;100(4):952-9.
2007: Alberto M Martelli; Lucio Cocco; Silvano Capitani; Sebastiano Miscia; Stefano Papa; Francesco Antonio Manzoli
Nuclear phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3-kinase, Akt, and PTen: emerging key regulators of anti-apoptotic signaling and carcinogenesis.
European journal of histochemistry : EJH 2007;51 Suppl 1():125-31.
2007: Alberto M Martelli; Pier Luigi Tazzari; Camilla Evangelisti; Francesca Chiarini; W L Blalock; Anna Maria Billi; Lucia Manzoli; JA McCubrey; Lucio Cocco
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
Current medicinal chemistry 2007;14(19):2009-23.
2007: Alberto M Martelli; Camilla Evangelist; Anna Maria Billi; Lucia Manzoli; Veronica Papa; Lucio Cocco
Intranuclear 3'-phosphoinositide metabolism and apoptosis protection in PC12 cells.
Acta bio-medica : Atenei Parmensis 2007;78 Suppl 1():113-9.
2007: Lucio Cocco; Matilde Y Follo; Irene Faenza; Alberto Bavelloni; Anna Maria Billi; Alberto M Martelli; Lucia Manzoli
Nuclear inositide signaling: an appraisal of phospholipase C beta 1 behavior in myelodysplastic and leukemia cells.
Advances in enzyme regulation 2007;47():2-9.
2006: Alberto Bavelloni; Irene Faenza; Gabriella Cioffi; Manuela Piazzi; Daniela Parisi; Ivan Matic; Nadir M Maraldi; Lucio Cocco
Proteomic-based analysis of nuclear signaling: PLCbeta1 affects the expression of the splicing factor SRp20 in Friend erythroleukemia cells.
Proteomics 2006;6(21):5725-34.
2006: Camilla Evangelisti; Massimo Riccio; Irene Faenza; Nicoletta Zini; Yasukazu Hozumi; Kaoru Goto; Lucio Cocco; Alberto M Martelli
Subnuclear localization and differentiation-dependent increased expression of DGK-zeta in C2C12 mouse myoblasts.
Journal of cellular physiology 2006;209(2):370-8.
2006: Giuliana Gobbi; Ivonne Sponzilli; Prisco Mirandola; Pier Luigi Tazzari; Luigi Caimi; Antonio Cacchioli; Alessandro Matteucci; Gabriella Giuliani-Piccari; Lucio Cocco; Marco Vitale
Efficient platelet delta-granule release induced by [Ca2+]i elevation is modulated by GPIIbIIIa.
International journal of molecular medicine 2006;18(2):309-13.
2006: Matilde Y Follo; Costanza Bosi; Carlo Finelli; Roberta Fiume; Irene Faenza; Giulia Ramazzotti; Gian Carlo Gaboardi; Lucia Manzoli; Lucio Cocco
Real-time PCR as a tool for quantitative analysis of PI-PLCbeta1 gene expression in myelodysplastic syndrome.
International journal of molecular medicine 2006;18(2):267-71.
2006: Alberto M Martelli; Irene Faenza; Anna Maria Billi; Lucia Manzoli; Camilla Evangelisti; Federica Falà; Lucio Cocco
Intranuclear 3'-phosphoinositide metabolism and Akt signaling: new mechanisms for tumorigenesis and protection against apoptosis?
Cellular signalling 2006;18(8):1101-7.
2006: Alberto M Martelli; Maria Nyåkern; Giovanna Tabellini; Roberta Bortul; Pier Luigi Tazzari; Camilla Evangelisti; Lucio Cocco
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
Leukemia 2006;20(6):911-28.
2006: Irina Mantovani; Alessandra Cappellini; Pier Luigi Tazzari; Veronica Papa; Lucio Cocco; Alberto M Martelli
Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells.
Journal of cellular physiology 2006;207(3):836-44.
2006: Lucio Cocco; Irene Faenza; Roberta Fiume; Anna Maria Billi; R Stewart Gilmour; Francesco Antonio Manzoli
Phosphoinositide-specific phospholipase C (PI-PLC) beta1 and nuclear lipid-dependent signaling.
Biochimica et biophysica acta 2006;1761(5-6):509-21.
2006: Vincenza Rita Lo Vasco; M Y Follo; Lucio Cocco
Reply to Herens et al.
Leukemia 2006;20(4):755.
2006: Maria Nyåkern; Pier Luigi Tazzari; Carlo Finelli; Costanza Bosi; Matilde Y Follo; Tiziana Grafone; Pier Paolo Piccaluga; giovanni martinelli; Lucio Cocco; Alberto M Martelli
Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients.
Leukemia 2006;20(2):230-8.
2006: Prisco Mirandola; Giuliana Gobbi; Cristina Ponti; Ivonne Sponzilli; Lucio Cocco; Marco Vitale
PKCepsilon controls protection against TRAIL in erythroid progenitors.
Blood 2006;107(2):508-13.
2006: Lucio Cocco; Alberto M Martelli; Roberta Fiume; Irene Faenza; Anna Maria Billi; Francesco Antonio Manzoli
Signal transduction within the nucleus: revisiting phosphoinositide inositide-specific phospholipase Cbeta1.
Advances in enzyme regulation 2006;46():2-11.
2006: Camilla Evangelisti; Roberta Bortul; Giovanna Tabellini; Veronica Papa; Lucio Cocco; Alberto M Martelli
Nuclear expression of diacylglycerol kinases: possible involvement in DNA replication.
European journal of histochemistry : EJH 2006;50(1):9-13.
2006: Prisco Mirandola; Ivonne Sponzilli; Giuliana Gobbi; Sandra Marmiroli; Laura Rinaldi; Roberto Binazzi; Gabriella Giuliani Piccari; Giulia Ramazzotti; Gian Carlo Gaboardi; Lucio Cocco; Marco Vitale
Anticancer agents sensitize osteosarcoma cells to TNF-related apoptosis-inducing ligand downmodulating IAP family proteins.
International journal of oncology 2006;28(1):127-33.
2005: Alessandra Cappellini; Irina Mantovani; Pier Luigi Tazzari; Tiziana Grafone; giovanni martinelli; Lucio Cocco; Alberto M Martelli
Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts.
International journal of molecular medicine 2005;16(6):1041-8.
2005: Alberto M Martelli; Roberta Fiume; Irene Faenza; Giovanna Tabellini; C Evangelista; Roberta Bortul; Matilde Y Follo; Federica Falà; Lucio Cocco
Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal transduction.
Histology and histopathology 2005;20(4):1251-60.
2005: Alberto M Martelli; Matilde Y Follo; Camilla Evangelisti; Federica Falà; Roberta Fiume; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid metabolism: more than just second messenger generation?
Journal of cellular biochemistry 2005;96(2):285-92.
2005: Alessandra Ruggeri; Lucio Montebugnoli; Alessandro Matteucci; Nicoletta Zini; Liliana Solimando; Dora Servidio; Pietro Suppa; Milena Cadenaro; Lucio Cocco; Lorenzo Breschi
Cyclosporin A specifically affects nuclear PLCbeta1 in immunodepressed heart transplant patients with gingival overgrowth.
Journal of dental research 2005;84(8):747-51.
2005: Lucia Manzoli; Alberto M Martelli; Anna Maria Billi; Irene Faenza; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C: involvement in signal transduction.
Progress in lipid research 2005;44(4):185-206.
2005: Roberta Fiume; Irene Faenza; Alessandro Matteucci; Annalisa Astolfi; Marco Vitale; Alberto M Martelli; Lucio Cocco
Nuclear phospholipase C beta1 (PLCbeta1) affects CD24 expression in murine erythroleukemia cells.
The Journal of biological chemistry 2005;280(25):24221-6.
2005: Irene Faenza; Anna Maria Billi; Matilde Y Follo; Roberta Fiume; Alberto M Martelli; Lucio Cocco; Lucia Manzoli
Nuclear phospholipase C signaling through type 1 IGF receptor and its involvement in cell growth and differentiation.
Anticancer research 2005;25(3B):2039-41.
2005: Giovanna Tabellini; Alessandra Cappellini; Pier Luigi Tazzari; Federica Falà; Anna Maria Billi; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
Journal of cellular physiology 2005;202(2):623-34.
2005: Lucio Cocco; Lucia Manzoli; Giandomenico Palka; Alberto M Martelli
Nuclear phospholipase C beta1, regulation of the cell cycle and progression of acute myeloid leukemia.
Advances in enzyme regulation 2005;45():126-35.
2005: Alberto M Martelli; Giovanna Tabellini; Roberta Bortul; Pier Luigi Tazzari; Alessandra Cappellini; Anna Maria Billi; Lucio Cocco
Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in the resistance to therapeutic treatments of human leukemias.
Histology and histopathology 2005;20(1):239-52.
2004: Giuliana Gobbi; Prisco Mirandola; Cristina Micheloni; Elvira Solenghi; Ivonne Sponzilli; Marino Artico; Giuseppe Soda; Giuliana Zanelli; Giuseppe Pelusi; Tania Fiorini; Lucio Cocco; Marco Vitale
Expression of HLA class I antigen and proteasome subunits LMP-2 and LMP-10 in primary vs. metastatic breast carcinoma lesions.
International journal of oncology 2004;25(6):1625-9.
2004: Vittoria Cenni; Nadir M Maraldi; Alessandra Ruggeri; Paola Secchiero; Rosalba Del Coco; Anto De Pol; Lucio Cocco; Sandra Marmiroli
Sensitization of multidrug resistant human ostesarcoma cells to Apo2 Ligand/TRAIL-induced apoptosis by inhibition of the Akt/PKB kinase.
International journal of oncology 2004;25(6):1599-608.
2004: Giovanna Tabellini; Anna Maria Billi; Federica Falà; Alessandra Cappellini; Camilla Evagelisti; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells.
Cellular signalling 2004;16(11):1263-71.
2004: Prisco Mirandola; Cristina Ponti; Giuliana Gobbi; Ivonne Sponzilli; Mauro Vaccarezza; Lucio Cocco; giorgio zauli; Paola Secchiero; Francesco Antonio Manzoli; Marco Vitale
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity.
Blood 2004;104(8):2418-24.
2004: Giovanna Tabellini; Pier Luigi Tazzari; Roberta Bortul; Anna Maria Billi; Roberto Conte; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
British journal of haematology 2004;126(4):574-82.
2004: Marco Vitale; Rita Rezzani; Giuliana Gobbi; Cristina Ponti; Alessandro Matteucci; Antonio Cacchioli; Alessandra Ruggeri; Lucio Cocco
Phospholipase-C beta1 is predominantely expressed in the granular layer of rat cerebellar cortex.
International journal of molecular medicine 2004;14(2):161-4.
2004: Irene Faenza; Alberto Bavelloni; Roberta Fiume; Patrizia Santi; Alberto M Martelli; Anna Maria Billi; Vincenza Rita Lo Vasco; Lucia Manzoli; Lucio Cocco
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.
Journal of cellular physiology 2004;200(2):291-6.
2004: Vincenza Rita Lo Vasco; Giuseppe Calabrese; Lucia Manzoli; Giandomenico Palka; Antonio Spadano; Elisena Morizio; Paolo Guanciali Franchi; Donatella Fantasia; Lucio Cocco
Inositide-specific phospholipase c beta1 gene deletion in the progression of myelodysplastic syndrome to acute myeloid leukemia.
Leukemia 2004;18(6):1122-6.
2004: Alberto M Martelli; Federica Falà; Irene Faenza; Anna Maria Billi; Alessandra Cappellini; Lucia Manzoli; Lucio Cocco
Metabolism and signaling activities of nuclear lipids.
Cellular and molecular life sciences : CMLS 2004;61(10):1143-56.
2004: Milena Merlo Pich; Nicola Raule; Lucia Catani; Maria Elena Fagioli; Irene Faenza; Lucio Cocco; Giorgio Lenaz
Increased transcription of mitochondrial genes for Complex I in human platelets during ageing.
FEBS letters 2004;558(1-3):19-22.
2004: Lucio Cocco; Lucia Manzoli; Ottavio Barnabei; Alberto M Martelli
Significance of subnuclear localization of key players of inositol lipid cycle.
Advances in enzyme regulation 2004;44():51-60.
2004: Lucio Cocco; S Capitani; N M Maraldi; Alberto M Martelli; Giovanni Mazzotti; Francesco Antonio Manzoli
Significance of nuclear phospholipase C signaling through type 1 IGF receptor.
Journal of endocrinological investigation 2004;27(6 Suppl):143-5.
2004: Lucia Manzoli; Anna Maria Billi; Alberto M Martelli; Lucio Cocco
Regulation of nuclear phospholipase C activity.
Acta biochimica Polonica 2004;51(2):391-5.
2004: Lucio Cocco; Nadir M Maraldi; Francesco Antonio Manzoli
New frontiers of inositide-specific phospholipase C in nuclear signalling.
European journal of histochemistry : EJH 2004;48(1):83-8.
2004: Alberto M Martelli; Lucia Manzoli; Lucio Cocco
Nuclear inositides: facts and perspectives.
Pharmacology & therapeutics 2004;101(1):47-64.
2003: Alessandra Cappellini; Giovanna Tabellini; Margit Zweyer; Roberta Bortul; Pier Luigi Tazzari; Anna Maria Billi; Federica Falà; Lucio Cocco; Alberto M Martelli
The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
Leukemia 2003;17(11):2157-67.
2003: Elisabetta Falcieri; Sabrina Burattini; Roberta Bortul; Francesca Luchetti; Giovanna Tabellini; Pier Luigi Tazzari; Alessandra Cappellini; Lucio Cocco; Alberto M Martelli
Intranucleolar localization of DNA topoisomerase IIalpha is a distinctive feature of necrotic, but not of apoptotic, Jurkat T-cells.
Microscopy research and technique 2003;62(3):192-200.
2003: Alberto M Martelli; Irene Faenza; Anna Maria Billi; Federica Falà; Lucio Cocco; Lucia Manzoli
Nuclear protein kinase C isoforms: key players in multiple cell functions?
Histology and histopathology 2003;18(4):1301-12.
2003: Alberto M Martelli; Pier Luigi Tazzari; Giovanna Tabellini; Roberta Bortul; Anna Maria Billi; Lucia Manzoli; A Ruggeri; Roberto Conte; Lucio Cocco
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
Leukemia 2003;17(9):1794-805.
2003: Giovanna Tabellini; Roberta Bortul; Spartaco Santi; Massimo Riccio; Giovanna Baldini; Alessandra Cappellini; Anna Maria Billi; Ronald Berezney; Alessandra Ruggeri; Lucio Cocco; Alberto M Martelli
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.
Experimental cell research 2003;287(1):143-54.
2003: Irene Faenza; Alberto Bavelloni; Roberta Fiume; Giovanna Lattanzi; Nadir M Maraldi; R Stewart Gilmour; Alberto M Martelli; Pann-Ghill Suh; Anna Maria Billi; Lucio Cocco
Up-regulation of nuclear PLCbeta1 in myogenic differentiation.
Journal of cellular physiology 2003;195(3):446-52.
2003: Roberta Bortul; Pier Luigi Tazzari; Alessandra Cappellini; Giovanna Tabellini; Anna Maria Billi; Renato Bareggi; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.
Leukemia 2003;17(2):379-89.
2003: Lucio Cocco; Lucia Manzoli; Ottavio Barnabei; R Stewart Gilmour; Alberto M Martelli
Re-examination of the significance of nuclear localization of PLCbeta1 in the likelihood of its involvement in neoplastic cell growth.
Advances in enzyme regulation 2003;43():1-13.
2003: Amelia Cataldi; Roberta Di Pietro; Lucia Centurione; Monica Rapino; Eugenio Santavenere; Francesco Garaci; Lucio Cocco; Gabriella Giuliani-Piccari; Rosa Alba Rana
Engagement of PI-3-kinase mediated protein kinase C zeta activation in protecting Friend cells from ionizing radiation-induced apoptosis.
International journal of oncology 2003;22(1):129-35.
2002: Cristina Ponti; Davide Gibellini; Francesco Boin; Edon Melloni; Francesco Antonio Manzoli; Lucio Cocco; giorgio zauli; Marco Vitale
Role of CREB transcription factor in c-fos activation in natural killer cells.
European journal of immunology 2002;32(12):3358-65.
2002: Alberto M Martelli; Lucia Manzoli; Irene Faenza; Roberta Bortul; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid signaling and its potential involvement in malignant transformation.
Biochimica et biophysica acta 2002;1603(1):11-7.
2002: Alberto M Martelli; Elisabetta Falcieri; Margit Zweyer; Roberta Bortul; Giovanna Tabellini; Alessandra Cappellini; Lucio Cocco; Lucia Manzoli
The controversial nuclear matrix: a balanced point of view.
Histology and histopathology 2002;17(4):1193-205.
2002: Daniela Peruzzi; Michela Aluigi; Lucia Manzoli; Anna Maria Billi; Francesco Paolo Di Giorgio; Manuela Morleo; Alberto M Martelli; Lucio Cocco
Molecular characterization of the human PLC beta1 gene.
Biochimica et biophysica acta 2002;1584(1):46-54.
2002: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Renato Bareggi; Lucia Manzoli; Paola Narducci; Lucio Cocco
Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways.
Cellular and molecular life sciences : CMLS 2002;59(7):1129-37.
2002: Marino Artico; Sandro Bosco; Carlo Cavallotti; Enzo Agostinelli; Gabriella Giuliani-Piccari; Salvatore Sciorio; Lucio Cocco; Marco Vitale
Noradrenergic and cholinergic innervation of the bone marrow.
International journal of molecular medicine 2002;10(1):77-80.
2002: Irene Faenza; Alessandro Matteucci; Alberto Bavelloni; Sandra Marmiroli; Alberto M Martelli; R Stewart Gilmour; Pann-Ghill Suh; Lucia Manzoli; Lucio Cocco
Nuclear PLCbeta(1) acts as a negative regulator of p45/NF-E2 expression levels in Friend erythroleukemia cells.
Biochimica et biophysica acta 2002;1589(3):305-10.
2002: Lucio Cocco; Alberto M Martelli; Marco Vitale; Mirella Falconi; Ottavio Barnabei; R Stewart Gilmour; Francesco Antonio Manzoli
Inositides in the nucleus: regulation of nuclear PI-PLCbeta1.
Advances in enzyme regulation 2002;42():181-93.
2002: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Irene Faenza; Alessandra Cappellini; Renato Bareggi; Lucia Manzoli; Lucio Cocco
Molecular characterization of protein kinase C-alpha binding to lamin A.
Journal of cellular biochemistry 2002;86(2):320-30.
2002: Cristina Ponti; Mirella Falconi; Anna Maria Billi; Irene Faenza; Sergio Castorina; Luigi Caimi; Antonio Cacchioli; Lucio Cocco; Marco Vitale
IL-12 and IL-15 induce activation of nuclear PLCbeta in human natural killer cells.
International journal of oncology 2002;20(1):149-53.
2001: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Michela Aluigi; Daniela Peruzzi; Renato Bareggi; Paola Narducci; Lucio Cocco
Re-examination of the mechanisms regulating nuclear inositol lipid metabolism.
FEBS letters 2001;505(1):1-6.
2001: Marco Vitale; Alessandro Matteucci; Lucia Manzoli; Luigi Fabrizio Rodella; A R Mariani; giorgio zauli; Mirella Falconi; Anna Maria Billi; Alberto M Martelli; R Stewart Gilmour; Lucio Cocco
Interleukin 2 activates nuclear phospholipase Cbeta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1789-91.
2001: Aimin Xu; Pann-Ghill Suh; Nelly Marmy-Conus; Richard B Pearson; O Y Seok; Lucio Cocco; R Stewart Gilmour
Phosphorylation of nuclear phospholipase C beta1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I.
Molecular and cellular biology 2001;21(9):2981-90.
2001: Lucio Cocco; Alberto M Martelli; R Stewart Gilmour; SG Rhee; Francesco Antonio Manzoli
Nuclear phospholipase C and signaling.
Biochimica et biophysica acta 2001;1530(1):1-14.
2001: Lucio Cocco; Nadir M Maraldi; Silvano Capitani; Alberto M Martelli; Francesco Antonio Manzoli
Nuclear localization and signalling activity of inositol lipids.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(2 Suppl 1):31-43.
2001: Roberta Bortul; Margit Zweyer; Anna Maria Billi; Giovanna Tabellini; RL Ochs; Renato Bareggi; Lucio Cocco; Alberto M Martelli
Nuclear changes in necrotic HL-60 cells.
Journal of cellular biochemistry. Supplement 2001;Suppl 36():19-31.
2001: Lucio Cocco; Alberto M Martelli; Ottavio Barnabei; Francesco Antonio Manzoli
Nuclear inositol lipid signaling.
Advances in enzyme regulation 2001;41():361-84.
2000: Alberto M Martelli; Anna Maria Billi; Lucia Manzoli; Irene Faenza; Michela Aluigi; Mirella Falconi; Anto De Pol; R Stewart Gilmour; Lucio Cocco
Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation.
FEBS letters 2000;486(3):230-6.
2000: Irene Faenza; Alessandro Matteucci; Lucia Manzoli; Anna Maria Billi; Michela Aluigi; Daniela Peruzzi; Marco Vitale; S Castorina; Pann-Ghill Suh; Lucio Cocco
A role for nuclear phospholipase Cbeta 1 in cell cycle control.
The Journal of biological chemistry 2000;275(39):30520-4.
2000: Alberto M Martelli; I Robuffo; Roberta Bortul; RL Ochs; Francesca Luchetti; Lucio Cocco; Margit Zweyer; Renato Bareggi; E Falcieri
Behavior of nucleolar proteins during the course of apoptosis in camptothecin-treated HL60 cells.
Journal of cellular biochemistry 2000;78(2):264-77.
2000: Daniela Peruzzi; G Calabrese; Irene Faenza; Lucia Manzoli; Alessandro Matteucci; Fernando Gianfrancesco; Anna Maria Billi; L Stuppia; G Palka; Lucio Cocco
Identification and chromosomal localisation by fluorescence in situ hybridisation of human gene of phosphoinositide-specific phospholipase C beta(1).
Biochimica et biophysica acta 2000;1484(2-3):175-82.
2000: Alberto M Martelli; Giovanna Tabellini; Roberta Bortul; Lucia Manzoli; Renato Bareggi; Giovanna Baldini; V Grill; Margit Zweyer; Paola Narducci; Lucio Cocco
Enhanced nuclear diacylglycerol kinase activity in response to a mitogenic stimulation of quiescent Swiss 3T3 cells with insulin-like growth factor I.
Cancer research 2000;60(4):815-21.
2000: Lucio Cocco; SG Rhee; R Stewart Gilmour; Francesco Antonio Manzoli
Inositide-specific phospholipase C signalling in the nucleus.
European journal of histochemistry : EJH 2000;44(1):45-50.
2000: Lucio Cocco; Alberto M Martelli; Giovanni Mazzotti; Ottavio Barnabei; Francesco Antonio Manzoli
Inositides and the nucleus: phospholipase Cbeta family localization and signaling activity.
Advances in enzyme regulation 2000;40():83-95.
1999: Lucia Manzoli; Anna Maria Billi; Irene Faenza; Alessandro Matteucci; Alberto M Martelli; Daniela Peruzzi; Mirella Falconi; SG Rhee; R Stewart Gilmour; Lucio Cocco
Nuclear phospholipase C: a novel aspect of phosphoinositide signalling.
Anticancer research 1999;19(5A):3753-6.
1999: Lucio Cocco; S Rubbini; Lucia Manzoli; Anna Maria Billi; Irene Faenza; Daniela Peruzzi; Alessandro Matteucci; M Artico; R Stewart Gilmour; SG Rhee
Inositides in the nucleus: presence and characterisation of the isozymes of phospholipase beta family in NIH 3T3 cells.
Biochimica et biophysica acta 1999;1438(2):295-9.
1999: Alberto M Martelli; Lucio Cocco; Renato Bareggi; Giovanna Tabellini; R Rizzoli; M D Ghibellini; Paola Narducci
Insulin-like growth factor-I-dependent stimulation of nuclear phospholipase C-beta1 activity in Swiss 3T3 cells requires an intact cytoskeleton and is paralleled by increased phosphorylation of the phospholipase.
Journal of cellular biochemistry 1999;72(3):339-48.
1999: Lucio Cocco; Silvano Capitani; Ottavio Barnabei; R Stewart Gilmour; SG Rhee; Francesco Antonio Manzoli
Inositides in the nucleus: further developments on phospholipase C beta 1 signalling during erythroid differentiation and IGF-I induced mitogenesis.
Advances in enzyme regulation 1999;39():287-97.
1998: Alessandro Matteucci; Irene Faenza; R Stewart Gilmour; Lucia Manzoli; Anna Maria Billi; Daniela Peruzzi; Alberto Bavelloni; SG Rhee; Lucio Cocco
Nuclear but not cytoplasmic phospholipase C beta 1 inhibits differentiation of erythroleukemia cells.
Cancer research 1998;58(22):5057-60.
1998: Lucio Cocco; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; R Rizzoli; R Stewart Gilmour; Karel Wirtz; SG Rhee; Francesco Antonio Manzoli
Inositides in the nucleus: taking stock of PLC beta 1.
Advances in enzyme regulation 1998;38():351-63.
1997: Anna Maria Billi; Alessandro Matteucci; Irene Faenza; Lucia Manzoli; S Rubbini; R Stewart Gilmour; SG Rhee; Lucio Cocco
Control of expression of PLCbeta1 by LAC repressor system: relationship between nuclear PLCbeta1 overexpression and growth factor stimulation.
Biochemical and biophysical research communications 1997;241(1):122-6.
1997: Lucia Manzoli; Anna Maria Billi; S Rubbini; Alberto Bavelloni; Irene Faenza; R Stewart Gilmour; SG Rhee; Lucio Cocco
Essential role for nuclear phospholipase C beta1 in insulin-like growth factor I-induced mitogenesis.
Cancer research 1997;57(11):2137-9.
1997: S Rubbini; Lucio Cocco; Lucia Manzoli; J Lutterman; Anna Maria Billi; Alessandro Matteucci; Karel Wirtz
Phosphoinositide signalling in nuclei of Friend cells: DMSO-induced differentiation reduces the association of phosphatidylinositol-transfer protein with the nucleus.
Biochemical and biophysical research communications 1997;230(2):302-5.
1997: Nadir M Maraldi; Sandra Marmiroli; Lucio Cocco; Silvano Capitani; Ottavio Barnabei; Francesco Antonio Manzoli
Nuclear lipid-dependent signal transduction in human osteosarcoma cells.
Advances in enzyme regulation 1997;37():351-75.
1996: Lucia Manzoli; R S Gilmour; Alberto M Martelli; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid cycle: a new central intermediary in signal transduction.
Anticancer research 1996;16(6A):3283-6.
1996: Lucio Cocco; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; R S Gilmour; Francesco Antonio Manzoli
Inositol lipid cycle and autonomous nuclear signalling.
Advances in enzyme regulation 1996;36():101-14.
1995: Giuseppe Calabrese; R S Gilmour; Liborio Stuppia; Roberta Di Pietro; Giandomenico Palka; Lucio Cocco
Chromosome mapping of the rat phospholipase C beta 1 gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(8):549-50.
1995: Lucia Manzoli; Anna Maria Billi; R S Gilmour; Alberto M Martelli; Alessandro Matteucci; S Rubbini; G Weber; Lucio Cocco
Phosphoinositide signaling in nuclei of Friend cells: tiazofurin down-regulates phospholipase C beta 1.
Cancer research 1995;55(14):2978-80.
1995: Giovanni Mazzotti; Lucio Cocco; Francesco Antonio Manzoli
High resolution detection of human metaphase chromosomes.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 1995;100 Suppl 1():31-8.
1995: Alberto M Martelli; A Cataldi; Lucia Manzoli; Anna Maria Billi; S Rubbini; R S Gilmour; Lucio Cocco
Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation.
Cellular signalling 1995;7(1):53-6.
1995: Alberto M Martelli; Lucia Manzoli; S Rubbini; Anna Maria Billi; Renato Bareggi; Lucio Cocco
The protein composition of Friend cell nuclear matrix stabilized by various treatments. Different recovery of nucleolar proteins B23 and C23 and nuclear lamins.
Biology of the cell / under the auspices of the European Cell Biology Organization 1995;83(1):15-22.
1995: Lucio Cocco; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; R S Gilmour; Francesco Antonio Manzoli
Nuclear inositol lipid cycle and differentiation.
Advances in enzyme regulation 1995;35():23-33.
1994: Lucio Cocco; Alberto M Martelli; R S Gilmour
Inositol lipid cycle in the nucleus.
Cellular signalling 1994;6(5):481-5.
1994: Luca M Neri; Anna Maria Billi; Lucia Manzoli; S Rubbini; R S Gilmour; Lucio Cocco; Alberto M Martelli
Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF.
FEBS letters 1994;347(1):63-8.
1994: Alberto M Martelli; Anna Maria Billi; R S Gilmour; Luca M Neri; Lucia Manzoli; Andrea Ognibene; Lucio Cocco
Phosphoinositide signaling in nuclei of Friend cells: phospholipase C beta down-regulation is related to cell differentiation.
Cancer research 1994;54(10):2536-40.
1994: Sandra Marmiroli; Andrea Ognibene; Alberto Bavelloni; Caterina Cinti; Lucio Cocco; Nadir M Maraldi
Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells.
The Journal of biological chemistry 1994;269(1):13-6.
1994: Alberto M Martelli; Lucio Cocco
No discrete complexes containing DNA polymerase alpha activity can be solubilized from the heat-stabilized nuclear matrix prepared from HeLa S3 cells.
Cell biochemistry and function 1994;12(1):37-44.
1993: Nicoletta Zini; Alberto M Martelli; Lucio Cocco; Francesco Antonio Manzoli; Nadir M Maraldi
Phosphoinositidase C isoforms are specifically localized in the nuclear matrix and cytoskeleton of Swiss 3T3 cells.
Experimental cell research 1993;208(1):257-69.
1993: Anna Maria Billi; Lucio Cocco; Alberto M Martelli; R S Gilmour; G Weber
Tiazofurin-induced changes in inositol lipid cycle in nuclei of Friend erythroleukemia cells.
Biochemical and biophysical research communications 1993;195(1):8-12.
1993: Roberta Di Pietro; Rosa Alba Rana; Andrea Sciscio; Sandra Marmiroli; Anna Maria Billi; Amelia Cataldi; Lucio Cocco
Age-related events in human active T lymphocytes: changes in the phosphoinositidase C activity.
Biochemical and biophysical research communications 1993;194(1):566-70.
1993: A M Martelli; L M Neri; Anna Maria Billi; Renato Bareggi; Lucio Cocco
Absence of high levels of DNA polymerase alpha activity in the nuclear matrix prepared from mouse erythroleukemia cells.
Cell biology international 1993;17(7):635-43.
1993: Lucio Cocco; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; Francesco Antonio Manzoli
Nuclear phosphoinositidase C during growth factor stimulation.
Advances in enzyme regulation 1993;33():157-69.
1992: Alberto M Martelli; R S Gilmour; R Bareggi; Lucio Cocco
The effect of in vitro heat exposure on the recovery of nuclear matrix-bound DNA polymerase alpha activity during the different phases of the cell cycle in synchronized HeLa S3 cells.
Experimental cell research 1992;201(2):470-6.
1992: Alberto M Martelli; R S Gilmour; Valeria Bertagnolo; Luca M Neri; Lucia Manzoli; Lucio Cocco
Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells.
Nature 1992;358(6383):242-5.
1992: P Santi; Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Rosa Alba Rana; Amelia Cataldi; G Lattanzi; Renato Bareggi; Lucio Cocco
Changes in polyphosphoinositide levels in rat liver nuclei in response to prolactin, a known hepatic mitogen.
Cellular signalling 1992;4(4):385-91.
1992: Rosa Alba Rana; Roberta Di Pietro; A Antonucci; Amelia Cataldi; Sebastiano Miscia; M Vitale; Lucio Cocco
Age-related events in active T subpopulation. Changes in polyphosphoinositide metabolism during mitogenic activation.
Mechanisms of ageing and development 1992;64(1-2):61-7.
1992: Alberto M Martelli; Anna Maria Billi; R S Gilmour; Lucia Manzoli; Di Primio Roberto; Lucio Cocco
Mouse and human hemopoietic cell lines of erythroid lineage express lamins A,B and C.
Biochemical and biophysical research communications 1992;185(1):271-6.
1992: Alberto M Martelli; Elisabetta Falcieri; P Gobbi; Lucia Manzoli; Amelia Cataldi; Rosa Alba Rana; Lucio Cocco
Further considerations on the thermal stabilization of the nuclear matrix in mouse erythroleukemia cells.
Cell biology international reports 1992;16(4):307-17.
1992: Lucio Cocco; Alberto M Martelli; R S Gilmour; Rosa Alba Rana; Ottavio Barnabei; Francesco Antonio Manzoli
Changes in inositol lipid metabolism and protein kinase C translocation in nuclei of mitogen stimulated Swiss 3T3 cells.
Advances in enzyme regulation 1992;32():91-103.
1991: Alberto M Martelli; Elisabetta Falcieri; P Gobbi; Lucia Manzoli; R S Gilmour; Lucio Cocco
Heat-induced stabilization of the nuclear matrix: a morphological and biochemical analysis in murine erythroleukemia cells.
Experimental cell research 1991;196(2):216-25.
1991: Alberto M Martelli; R S Gilmour; Luca M Neri; Lucia Manzoli; A N Corps; Lucio Cocco
Mitogen-stimulated events in nuclei of Swiss 3T3 cells. Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis.
FEBS letters 1991;283(2):243-6.
1991: Alberto M Martelli; Luca M Neri; R S Gilmour; P J Barker; N S Huskisson; Francesco Antonio Manzoli; Lucio Cocco
Temporal changes in intracellular distribution of protein kinase C in Swiss 3T3 cells during mitogenic stimulation with insulin-like growth factor I and bombesin: translocation to the nucleus follows rapid changes in nuclear polyphosphoinositides.
Biochemical and biophysical research communications 1991;177(1):480-7.
1991: Sebastiano Miscia; Amelia Cataldi; R Lisio; G Tulipano; R Rizzoli; Rosa Alba Rana; Lucio Cocco
Interferon transiently modulates intranuclear signalling system in erythroleukemia Friend cells.
Cell biology international reports 1991;15(5):427-35.
1991: Alberto M Martelli; Lucio Cocco; Francesco Antonio Manzoli
On the association of DNA polymerase alpha activity with the nuclear matrix in HeLa cells.
Cell biology international reports 1991;15(2):131-40.
1990: Alberto M Martelli; R S Gilmour; Francesco Antonio Manzoli; Lucio Cocco
Calcium free inositol (1,4,5)-trisphosphate stimulates protein kinase C dependent protein phosphorylation in nuclei isolated from mitogen-treated Swiss 3T3 cells.
Biochemical and biophysical research communications 1990;173(1):149-55.
1990: Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Francesco Antonio Manzoli; Lucio Cocco
Temperature-dependent association of DNA polymerase alpha activity with the nuclear matrix.
Experimental cell research 1990;190(2):227-32.
1990: Amelia Cataldi; Sebastiano Miscia; R Lisio; Rosa Alba Rana; Lucio Cocco
Transient shift of diacylglycerol and inositol lipids induced by interferon in Daudi cells. Evidence for a different pattern between nuclei and intact cells.
FEBS letters 1990;269(2):465-8.
1990: Alberto M Martelli; Anna Maria Billi; C De Marchis; Lucia Manzoli; Lucio Cocco
Probing the sulfhydryl groups of nuclear matrix proteins with 6-iodoacetamidofluorescein.
Cell biology international reports 1990;14(5):409-18.
1989: Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Francesco Antonio Manzoli; Lucio Cocco
Mitogen-stimulated phosphorylation of nuclear proteins in Swiss 3T3 cells: evidence for a protein kinase C requirement.
Experimental cell research 1989;185(1):191-202.
1989: Lucio Cocco; A M Martelli; R S Gilmour; A Ognibene; Francesco Antonio Manzoli; R F Irvine
Changes in nuclear inositol phospholipids induced in intact cells by insulin-like growth factor I.
Biochemical and biophysical research communications 1989;159(2):720-5.
1989: Francesco Antonio Manzoli; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; R Rizzoli; Ottavio Barnabei; Lucio Cocco
Nuclear polyphosphoinositides during cell growth and differentiation.
Advances in enzyme regulation 1989;28():25-34.
1988: R S Gilmour; C G Prosser; I R Fleet; Lucio Cocco; J C Saunders; K D Brown; A N Corps
From animal to molecule: aspects of the biology of insulin-like growth factors.
The British journal of cancer. Supplement 1988;9():23-30.
1988: Lucio Cocco; A M Martelli; R S Gilmour; A Ognibene; Francesco Antonio Manzoli; R F Irvine
Rapid changes in phospholipid metabolism in the nuclei of Swiss 3T3 cells induced by treatment of the cells with insulin-like growth factor I.
Biochemical and biophysical research communications 1988;154(3):1266-72.
1988: Sebastiano Miscia; Amelia Cataldi; A Ognibene; A M Martelli; Lucia Manzoli; Anna Maria Billi; C De Marchis; Lucio Cocco
Evidence for a reduction of the replicative activity of matrix-bound DNA polymerase alpha following treatment with phospholipase C.
Cell biology international reports 1988;12(5):347-54.
1988: Lucio Cocco; S Papa; Nadir M Maraldi; P Santi; Alberto M Martelli; R Rizzoli; Francesco Antonio Manzoli
Chromatin structural transitions following histone H1 displacement by phosphatidylserine vesicles and low pH treatment. A multiparametric analysis involving flow cytometry, electron microscopy, and nuclease digestion.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1988;36(1):65-71.
1987: Lucio Cocco; R S Gilmour; Andrea Ognibene; A J Letcher; Francesco Antonio Manzoli; R F Irvine
Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation.
The Biochemical journal 1987;248(3):765-70.
1987: Lucio Cocco; Sebastiano Miscia; A Cataldi; S Capitani; Alessandro Matteucci; A M Martelli; Francesco Antonio Manzoli
Response of isolated nuclei to phospholipid vesicles: effect of phosphatidylserine on alpha and beta DNA polymerase activity.
Cell biology international reports 1987;11(5):397-403.
1987: Lucio Cocco; Alberto M Martelli; Anna Maria Billi; A Cataldi; Sebastiano Miscia; M R Mottola; Lucia Manzoli
Phospholipids as components of the nuclear matrix: their possible biological significance.
Basic and applied histochemistry 1987;31(3):413-9.
1986: Lucio Cocco; A M Martelli; Anna Maria Billi; Alessandro Matteucci; M Vitale; L M Neri; Francesco Antonio Manzoli
Changes in nucleosome structure and histone H3 accessibility. Iodoacetamidofluorescein labelling after treatment with phosphatidylserine vesicles.
Experimental cell research 1986;166(2):465-74.
1984: S Capitani; Lucio Cocco; Alessandro Matteucci; Elisabetta Caramelli; S Papa; Francesco Antonio Manzoli
Response of isolated nuclei to phospholipid vesicles: analysis of the nuclear proteins after treatment with phosphatidylserine and phosphatidylcholine and comparison with heparin.
Cell biology international reports 1984;8(4):289-96.