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Thomas Glaser

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Lev Prasov; Eduardo D Silva; Jane C Sowden; Aiysha Abid; Mark Borchert; Michael C Brodsky; Mehul T Dattani; Daniel Kelberman; Shagufta Khaliq; Amy Lewanda; Tehmina Masud; S Qasim Mehdi; Edward R Oliver; Thomas M Glaser
ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous.
Lev Prasov; Thomas M Glaser
Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7).
Lev Prasov; Dellaney D Rudolph; Melinda Nagy; Thomas M Glaser
Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis.

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All Publications

2012: Lev Prasov; Eduardo D Silva; Jane C Sowden; Aiysha Abid; Mark Borchert; Michael C Brodsky; Mehul T Dattani; Daniel Kelberman; Shagufta Khaliq; Amy Lewanda; Tehmina Masud; S Qasim Mehdi; Edward R Oliver; Thomas M Glaser
ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous.
Human molecular genetics 2012;21(16):3681-94.
2012: Lev Prasov; Thomas M Glaser
Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7).
Developmental biology 2012;368(2):214-30.
2012: Lev Prasov; Dellaney D Rudolph; Melinda Nagy; Thomas M Glaser
Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis.
Neuroreport 2012;23(10):631-4.
2012: Lev Prasov; Thomas M Glaser
Dynamic expression of ganglion cell markers in retinal progenitors during the terminal cell cycle.
Molecular and cellular neurosciences 2012;50(2):160-8.
2012: Joseph A Brzezinski; Lev Prasov; Thomas M Glaser
Math5 defines the ganglion cell competence state in a subpopulation of retinal progenitor cells exiting the cell cycle.
Developmental biology 2012;365(2):395-413.
2012: Bethany A Volkmann Kloss; Linda M Reis; Dominique Brémond-Gignac; Thomas M Glaser; Elena V Semina
Analysis of FOXD3 sequence variation in human ocular disease.
Molecular vision 2012;18():1740-9.
2011: Noor M Ghiasvand; Dellaney D Rudolph; Mohammad Mashayekhi; Joseph A Brzezinski; Daniel Goldman; Thomas M Glaser
Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease.
Nature neuroscience 2011;14(5):578-86.
2010: Lev Prasov; Nadean L Brown; Thomas M Glaser
A critical analysis of Atoh7 (Math5) mRNA splicing in the developing mouse retina.
PloS one 2010;5(8):e12315.
2008: Aytekin Akyol; Takao Hinoi; Ying Feng; Bommer Guido; Thomas M Glaser; Guido Bommer
Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene.
Nature methods 2008;5(3):231-3.
2008: Sara M Saul; Joseph A Brzezinski; Richard A Altschuler; Susan E Shore; Dellaney D Rudolph; Lisa L Kabara; Kärin Halsey; Robert B Hufnagel; Jianxun Zhou; David F Dolan; Thomas M Glaser
Math5 expression and function in the central auditory system.
Molecular and cellular neurosciences 2008;37(1):153-69.
2006: Masayuki Akimoto; Hong Cheng; Dongxiao Zhu; Joseph A Brzezinski; Ritu Khanna; Elena Filippova; Edwin C T Oh; Yuezhou Jing; Jose-Luis Linares; Matthew Brooks; Sepideh Zareparsi; Alan J Mears; Alfred O Hero; Thomas M Glaser; Anand Swaroop
Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3890-5.
2006: Andrea L Vincent; Gail Billingsley; Megan Priston; Thomas M Glaser; Edward Oliver; Mike Walter; Robert Ritch; Alex Levin; Elise Heon
Further support of the role of CYP1B1 in patients with Peters anomaly.
Molecular vision 2006;12():506-10.
2005: Joseph A Brzezinski; Nadean L Brown; Atsuhiro Tanikawa; Ronald A Bush; Paul Sieving; Martha Hotz Vitaterna; Joseph S Takahashi; Thomas M Glaser
Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice.
Investigative ophthalmology & visual science 2005;46(7):2540-51.
2004: Edward R Oliver; Thomas L Saunders; Susan A Tarlé; Thomas M Glaser
Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute.
Development (Cambridge, England) 2004;131(16):3907-20.
2003: Yan Sun; Shami L Kanekar; Monica L Vetter; Sharon Gorski; Yuh Nung Jan; Thomas M Glaser; Nadean L Brown
Conserved and divergent functions of Drosophila atonal, amphibian, and mammalian Ath5 genes.
Evolution & development 2003;5(5):532-41.
2002: Nadean L Brown; Susan L Dagenais; Chuan-Min Chen; Thomas M Glaser
Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development.
Mammalian genome : official journal of the International Mammalian Genome Society 2002;13(2):95-101.
2002: Rafal Farjo; Jindan YU; Mohammad I Othman; Shigeo Yoshida; Sujata Sheth; Thomas M Glaser; Wolfgang Baehr; Anand Swaroop
Mouse eye gene microarrays for investigating ocular development and disease.
Vision research 2002;42(4):463-70.
2001: P Tucker; L Laemle; A Munson; Shami L Kanekar; Edward R Oliver; N Brown; H Schlecht; Monica L Vetter; Thomas M Glaser
The eyeless mouse mutation (ey1) removes an alternative start codon from the Rx/rax homeobox gene.
Genesis (New York, N.Y. : 2000) 2001;31(1):43-53.
2001: Nadean L Brown; S Patel; Joseph A Brzezinski; Thomas M Glaser
Math5 is required for retinal ganglion cell and optic nerve formation.
Development (Cambridge, England) 2001;128(13):2497-508.
2001: Andrea L Vincent; Gail Billingsley; Megan Priston; Donna Williams-Lyn; J Sutherland; Thomas M Glaser; Edward R Oliver; M A Walter; G Heathcote; A Levin; Elise Héon
Phenotypic heterogeneity of CYP1B1: mutations in a patient with Peters' anomaly.
Journal of medical genetics 2001;38(5):324-6.
2000: JD Lauderdale; Jonathan Wilensky; Edward R Oliver; D S Walton; Thomas M Glaser
3' deletions cause aniridia by preventing PAX6 gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13755-9.
2000: Jón Hallsteinn Hallsson; Jack Favor; CA Hodgkinson; Thomas M Glaser; M Lynn Lamoreux; R Magnúsdóttir; G J Gunnarsson; H O Sweet; Neal G Copeland; Nancy A Jenkins; Eiríkur Steingrímsson
Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus.
Genetics 2000;155(1):291-300.
1998: Nadean L Brown; Shami L Kanekar; Monica L Vetter; Priscilla K Tucker; DL Gemza; Thomas M Glaser
Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis.
Development (Cambridge, England) 1998;125(23):4821-33.
1998: CA Hodgkinson; A Nakayama; H Li; L B Swenson; K Opdecamp; J H Asher; Heinz Arnheiter; Thomas M Glaser
Mutation at the anophthalmic white locus in Syrian hamsters: haploinsufficiency in the Mitf gene mimics human Waardenburg syndrome type 2.
Human molecular genetics 1998;7(4):703-8.
1994: J A Epstein; Thomas M Glaser; J Cai; L Jepeal; D S Walton; Richard L Maas
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing.
Genes & development 1994;8(17):2022-34.
1994: Thomas M Glaser; L Jepeal; J G Edwards; S Robert Young; J Favor; Richard L Maas
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects.
Nature genetics 1994;7(4):463-71.
1994: J Epstein; J Cai; Thomas M Glaser; L Jepeal; R Maas
Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes.
The Journal of biological chemistry 1994;269(11):8355-61.
1994: R Maas; S Elfering; Thomas M Glaser; L Jepeal
Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;199(3):214-28.
1994: Thomas M Glaser; C C Ton; R Mueller; Maria-Luiza Petzl-Erler; C Oliver; N C Nevin; D E Housman; R L Maas
Absence of PAX6 gene mutations in Gillespie syndrome (partial aniridia, cerebellar ataxia, and mental retardation).
Genomics 1994;19(1):145-8.
1992: Thomas M Glaser; D S Walton; Richard L Maas
Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene.
Nature genetics 1992;2(3):232-9.
1992: K M Call; C Y Ito; C Lindberg; A Memisoglu; C Petrou; Thomas M Glaser; C Jones; David E Housman
Mapping and characterization of 129 cosmids on human chromosome 11p.
Somatic cell and molecular genetics 1992;18(5):463-75.
1992: Catharina Larsson; Günther Weber; E Kvanta; K Lewis; M Janson; C Jones; Thomas M Glaser; G Evans; Magnus Nordenskjöld
Isolation and mapping of polymorphic cosmid clones used for sublocalization of the multiple endocrine neoplasia type 1 (MEN1) locus.
Human genetics 1992;89(2):187-93.
1992: M A Oettinger; B Stanger; David G Schatz; Thomas M Glaser; K Call; D Housman; David Baltimore
The recombination activating genes, RAG 1 and RAG 2, are on chromosome 11p in humans and chromosome 2p in mice.
Immunogenetics 1992;35(2):97-101.
1992: A Tanigami; T Tokino; S Takiguchi; M Mori; Thomas M Glaser; J W Park; C Jones; Y Nakamura
Mapping of 262 DNA markers into 24 intervals on human chromosome 11.
American journal of human genetics 1992;50(1):56-64.
1991: M Janson; Catharina Larsson; B Werelius; C Jones; Thomas M Glaser; Y Nakamura; C P Jones; Magnus Nordenskjöld
Detailed physical map of human chromosomal region 11q12-13 shows high meiotic recombination rate around the MEN1 locus.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10609-13.
1991: J Pelletier; W Bruening; Frederick P Li; Daniel A Haber; Thomas M Glaser; David E Housman
WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour.
Nature 1991;353(6343):431-4.
1991: AJ Buckler; J Pelletier; Daniel A Haber; Thomas M Glaser; David E Housman
Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.
Molecular and cellular biology 1991;11(3):1707-12.
1991: Brigitte Royer-Pokora; S Ragg; B Heckl-Ostreicher; M Held; U Loos; K Call; Thomas M Glaser; D Housman; G Saunders; Bernhard Zabel
Direct pulsed field gel electrophoresis of Wilms' tumors shows that DNA deletions in 11p13 are rare.
Genes, chromosomes & cancer 1991;3(2):89-100.
1991: T Tokino; E Takahashi; M Mori; A Tanigami; Thomas M Glaser; J W Park; C Jones; T Hori; Y Nakamura
Isolation and mapping of 62 new RFLP markers on human chromosome 11.
American journal of human genetics 1991;48(2):258-68.
1990: Thomas M Glaser; J Lane; D Housman
A mouse model of the aniridia-Wilms tumor deletion syndrome.
Science (New York, N.Y.) 1990;250(4982):823-7.
1990: Cécile Jeanpierre; Corinne Antignac; C Beroud; C Lavedan; I Henry; G Saunders; B Williams; Thomas M Glaser; Claudine Junien
Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor.
Genomics 1990;7(3):434-8.
1990: Daniel A Haber; AJ Buckler; Thomas M Glaser; K M Call; J Pelletier; R L Sohn; E C Douglass; David E Housman
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.
Cell 1990;61(7):1257-69.
1990: K M Call; Thomas M Glaser; C Y Ito; AJ Buckler; J Pelletier; Daniel A Haber; E A Rose; A Kral; Herman Yeger; W H Lewis
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus.
Cell 1990;60(3):509-20.
1990: E A Rose; Thomas M Glaser; C Jones; C L Smith; W H Lewis; K M Call; Mark D Minden; E Champagne; L Bonetta; Herman Yeger
Complete physical map of the WAGR region of 11p13 localizes a candidate Wilms' tumor gene.
Cell 1990;60(3):495-508.
1990: Thomas M Glaser; E Rose; H Morse; D Housman; C Jones
A panel of irradiation-reduced hybrids selectively retaining human chromosome 11p13: their structure and use to purify the WAGR gene complex.
Genomics 1990;6(1):48-64.
1990: M H Brilliant; G Szabo; Z Katarova; C A Kozak; Thomas M Glaser; Ralph J Greenspan; D E Housman
Sequences homologous to glutamic acid decarboxylase cDNA are present on mouse chromosomes 2 and 10.
Genomics 1990;6(1):115-22.
1989: Thomas M Glaser; D Housman; W H Lewis; D Gerhard; C Jones
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids.
Somatic cell and molecular genetics 1989;15(6):477-501.
1989: Thomas M Glaser; D J Driscoll; S Antonarakis; David Valle; D Housman
A highly polymorphic locus cloned from the breakpoint of a chromosome 11p13 deletion associated with the WAGR syndrome.
Genomics 1989;5(4):880-93.
1989: Thomas M Glaser; K E Matthews; J W Hudson; P Seth; David E Housman; M M Crerar
Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.
Genomics 1989;5(3):510-21.
1989: I Henry; Sophie Grandjouan; P Couillin; F Barichard; C Huerre-Jeanpierre; Thomas M Glaser; T Philip; G Lenoir; J L Chaussain; Claudine Junien
Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3247-51.
1989: Sherri J Bale; Allen E Bale; K Stewart; L Dachowski; O W McBride; Thomas M Glaser; Jeffrey E Green; J J Mulvihill; M L Brandi; Kazuyasu Sakaguchi
Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11.
Genomics 1989;4(3):320-2.
1988: H G Harley; J David Brook; C L Jackson; Thomas M Glaser; K V Walsh; M Sarfarazi; R Kent; M Lager; M Koch; Peter S Harper
Localization of a human Na+,K+-ATPase alpha subunit gene to chromosome 19q12----q13.2 and linkage to the myotonic dystrophy locus.
Genomics 1988;3(4):380-4.
1988: J Luty; J Kellogg; Cheryl L Maslen; C Jones; Thomas M Glaser; M Litt
Phage 8-10 identifies an RFLP on 11q23-qter [HGM9 no. D11S286].
Nucleic acids research 1988;16(14B):7210.
1988: Cheryl L Maslen; C Jones; Thomas M Glaser; R Ellen Magenis; R Sheehy; J Kellogg; M Litt
Seven polymorphic loci mapping to human chromosomal region 11q22-qter.
Genomics 1988;2(1):66-75.
1987: R B Kent; D A Fallows; E Geissler; Thomas M Glaser; J R Emanuel; P A Lalley; Robert Levenson; David E Housman
Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(15):5369-73.
1987: J L Arriza; C Weinberger; G Cerelli; Thomas M Glaser; B L Handelin; D E Housman; Ronald M Evans
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.
Science (New York, N.Y.) 1987;237(4812):268-75.
1986: Thomas M Glaser; W H Lewis; G A Bruns; P C Watkins; Charles E Rogler; T B Shows; V E Powers; H F Willard; J M Goguen; K O Simola
The beta-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus.
Nature 1986;321(6073):882-7.
1986: D E Housman; Thomas M Glaser; D S Gerhard; C Jones; G A Bruns; W H Lewis
Mapping of human chromosome 11: organization of genes within the Wilms' tumor region of the chromosome.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 2():837-41.