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Leendert Looijenga

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Sander G Basten; Erica E Davis; Nikolina Babala; Ad J M Gillis; Zachary G Heath; Trudy N Jonges; Nicholas Katsanis; René F Ketting; Ive Logister; Leendert H J Looijenga; Rene H Medema; Stefan Schulte-Merker; Hans Stoop; Fredericus J M van Eeden; Ellen van Rooijen; Emile E Voest; Rachel H Giles
Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas.
Achmad Zulfa Juniarto; Martine Cools; Stenvert L S Drop; Sultana M H Faradz; Remko Hersmus; Ika P Miranti; J Wolter Oosterhuis; Ardy Santosa; Bestari A Setyawati; hans stoop; Leendert H J Looijenga
Gonadal malignancy in 13 consecutive collected patients with disorders of sex development (DSD) from Semarang (Indonesia).
Sarah M Russell; Clive R Taylor; Christopher A French; Julie K Jang; Melissa G Lechner; Leendert H J Looijenga; Carolina Megiel; Anusuya Mokashi; Alan L Epstein
Establishment and characterization of a new human extragonadal germ cell line, SEM-1, and its comparison with TCam-2 and JKT-1.

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2013: Sander G Basten; Erica E Davis; Nikolina Babala; Ad J M Gillis; Zachary G Heath; Trudy N Jonges; Nicholas Katsanis; René F Ketting; Ive Logister; Leendert H J Looijenga; Rene H Medema; Stefan Schulte-Merker; Hans Stoop; Fredericus J M van Eeden; Ellen van Rooijen; Emile E Voest; Rachel H Giles
Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas.
PLoS genetics 2013;9(4):e1003384.
2013: Achmad Zulfa Juniarto; Martine Cools; Stenvert L S Drop; Sultana M H Faradz; Remko Hersmus; Ika P Miranti; J Wolter Oosterhuis; Ardy Santosa; Bestari A Setyawati; hans stoop; Leendert H J Looijenga
Gonadal malignancy in 13 consecutive collected patients with disorders of sex development (DSD) from Semarang (Indonesia).
Journal of clinical pathology 2013;66(3):198-204.
2013: Sarah M Russell; Clive R Taylor; Christopher A French; Julie K Jang; Melissa G Lechner; Leendert H J Looijenga; Carolina Megiel; Anusuya Mokashi; Alan L Epstein
Establishment and characterization of a new human extragonadal germ cell line, SEM-1, and its comparison with TCam-2 and JKT-1.
Urology 2013;81(2):464.e1-9.
2012: Cassy M Spiller; Chun-Wei Feng; Ad J M Gillis; Andrew Jackson; Peter Koopman; Leendert H J Looijenga; Antoine D Rolland; Josephine Bowles
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.
Development (Cambridge, England) 2012;139(22):4123-32.
2012: Justine J Cunningham; Martin F Pera; Thomas M Ulbright; Leendert H J Looijenga
Lessons from human teratomas to guide development of safe stem cell therapies.
Nature biotechnology 2012;30(9):849-57.
2012: Stefan White; Erin Turbitt; Yvonne van der Zwan; Martine Cools; Stenvert L S Drop; Vincent Harley; Remko Hersmus; Jacqueline Hewitt; Peter Koopman; Leendert H J Looijenga; Andrew Sinclair
A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development.
European journal of human genetics : EJHG 2012;20(3):348-51.
2012: Remko Hersmus; Katharina Biermann; Catharina Dhooge; Winand N M Dinjens; Stenvert L S Drop; Hendrikus J Dubbink; Ronak Eini; Isabelle C Meijssen; J Wolter Oosterhuis; Dominik Schneider; hans stoop; Gert-Jan M van de Geijn; Leendert H J Looijenga
Prevalence of c-KIT mutations in gonadoblastoma and dysgerminomas of patients with disorders of sex development (DSD) and ovarian dysgerminomas.
PloS one 2012;7(8):e43952.
2012: Remko Hersmus; Marielle Alders; Pascal Bernard; Hennie T Brüggenwirth; Suzan de Boer; Stenvert L S Drop; Vincent R Harley; Kenneth McElreavy; J Wolter Oosterhuis; Rajini Sreenivasan; hans stoop; Yvonne G van der Zwan; Stefan White; Katja P Wolffenbuttel; Leendert H J Looijenga
A 46,XY female DSD patient with bilateral gonadoblastoma, a novel SRY missense mutation combined with a WT1 KTS splice-site mutation.
PloS one 2012;7(7):e40858.
2012: Remko Hersmus; Luca Incrocci; Stenvert L S Drop; J Wolter Oosterhuis; hans stoop; Stefan J White; Katja P Wolffenbuttel; Leendert H J Looijenga
Delayed Recognition of Disorders of Sex Development (DSD): A Missed Opportunity for Early Diagnosis of Malignant Germ Cell Tumors.
International journal of endocrinology 2012;2012():671209.
2012: A Zulfa Juniarto; Leendert H J Looijenga; Renske Olmer; Ardy Santosa; Axel P N Themmen; Yvonne G van der Zwan; Katja P Wolffenbuttel; Hennie T Bruggenwirth; Frank H de Jong; Sultana M H Faradz; Remko Hersmus; Stenvert L S Drop
Application of the new classification on patients with a disorder of sex development in indonesia.
International journal of endocrinology 2012;2012():237084.
2011: Daniel Nettersheim; Katharina Biermann; Ad Gillis; Leendert H J Looijenga; Hubert Schorle
The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
Genes, chromosomes & cancer 2011;50(12):1033-42.
2011: J Wolter Oosterhuis; hans stoop; N van Casteren; Katja P Wolffenbuttel; W Boellaard; Gert R Dohle; Leendert H J Looijenga
A pathologist's view on the testis biopsy.
International journal of andrology 2011;34(4 Pt 2):e14-9; discussion e20.
2011: D Nettersheim; Ad J M Gillis; Leendert H J Looijenga; Hubert Schorle
TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma.
International journal of andrology 2011;34(4 Pt 2):e189-203.
2011: Ad J M Gillis; K Biermann; S Cribbes; Astrid Ferlinz; J Wolter Oosterhuis; M Shannon; hans stoop; E Swartzman; Ruud van Gurp; Leendert H J Looijenga
Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
International journal of andrology 2011;34(4 Pt 2):e160-74.
2011: Leendert H J Looijenga; K Biermann; Ad J M Gillis; hans stoop; J Wolter Oosterhuis
Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance.
International journal of andrology 2011;34(4 Pt 2):e234-51.
2011: Martine Cools; S L S Drop; P Hoebeke; J Lebl; Leendert H J Looijenga; J W Oosterhuis; J Pleskacova; H Stoop; E Van Laecke; Katja P Wolffenbuttel
Gonadal pathology and tumor risk in relation to clinical characteristics in patients with 45,X/46,XY mosaicism.
The Journal of clinical endocrinology and metabolism 2011;96(7):E1171-80.
2011: Annemieke M Boot; Stenvert L S Drop; Ada Funaro; Leendert H J Looijenga; Serge Lumbroso; Annette Richter-Unruh; André van Marle; Miriam Verhoef-Post; Auke Beishuizen; Axel P N Themmen
Mutation analysis of the LH receptor gene in Leydig cell adenoma and hyperplasia and functional and biochemical studies of activating mutations of the LH receptor gene.
The Journal of clinical endocrinology and metabolism 2011;96(7):E1197-205.
2011: Cindy LeBron; Prodipto Pal; Mariana Brait; Santanu Dasgupta; RAFAEL GUERRERO-PRESTON; Leendert H J Looijenga; Jeanne Kowalski; George Netto; Mohammad Hoque
Genome-wide analysis of genetic alterations in testicular primary seminoma using high resolution single nucleotide polymorphism arrays.
Genomics 2011;97(6):341-9.
2011: Frank Mayer; Hendrik Wermann; Peter Albers; hans stoop; Ad J M Gillis; Jörg T Hartmann; C Carsten Bokemeyer; J Wolter Oosterhuis; Leendert H J Looijenga; Friedemann Honecker
Histopathological and molecular features of late relapses in non-seminomas.
BJU international 2011;107(6):936-43.
2011: Hans Stoop; Wim Kirkels; Gert R Dohle; Ad J M Gillis; Michael A den Bakker; Katharina Biermann; Wolter Oosterhuis; Leendert H J Looijenga
Diagnosis of testicular carcinoma in situ '(intratubular and microinvasive)' seminoma and embryonal carcinoma using direct enzymatic alkaline phosphatase reactivity on frozen histological sections.
Histopathology 2011;58(3):440-6.
2011: Martine Cools; Stenvert L S Drop; J W Oosterhuis; Katja P Wolffenbuttel; Leendert H J Looijenga
Gonadal development and tumor formation at the crossroads of male and female sex determination.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2011;5(4):167-80.
2011: M Barbaro; M Cools; Stenvert L S Drop; Leendert H J Looijenga; Anna Wedell
Partial deletion of the NR5A1 (SF1) gene detected by synthetic probe MLPA in a patient with XY gonadal disorder of sex development.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2011;5(4):181-7.
2011: Daniel Nettersheim; Katharina Biermann; Ad J M Gillis; Klaus Steger; Leendert H J Looijenga; Hubert Schorle
NANOG promoter methylation and expression correlation during normal and malignant human germ cell development.
Epigenetics : official journal of the DNA Methylation Society 2011;6(1):114-22.
2010: Na Liu; Steven A Enkemann; Ping Liang; Remko Hersmus; Claudia Zanazzi; Junjiu Huang; Chao Wu; Zhisheng Chen; Leendert H J Looijenga; David L Keefe; Lin Liu
Genome-wide gene expression profiling reveals aberrant MAPK and Wnt signaling pathways associated with early parthenogenesis.
Journal of molecular cell biology 2010;2(6):333-44.
2010: Hendrik Wermann; hans stoop; Ad J M Gillis; Friedemann Honecker; Ruud van Gurp; Ole Ammerpohl; Julia Richter; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.
The Journal of pathology 2010;221(4):433-42.
2010: J W B de Groot; T P Links; Axel P N Themmen; Leendert H J Looijenga; Ronald R de Krijger; Peter M Van Koetsveld; Jan Hofland; G van den Berg; Leo Hofland; Richard A Feelders
Aberrant expression of multiple hormone receptors in ACTH-independent macronodular adrenal hyperplasia causing Cushing's syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2010;163(2):293-9.
2010: J E Elzinga-Tinke; M E Sirre; Leendert H J Looijenga; N van Casteren; Mark F Wildhagen; Gert R Dohle
The predictive value of testicular ultrasound abnormalities for carcinoma in situ of the testis in men at risk for testicular cancer.
International journal of andrology 2010;33(4):597-603.
2010: Leendert H J Looijenga; Remko Hersmus; Bertie de Leeuw; hans stoop; Martine Cools; J Wolter Oosterhuis; Stenvert L S Drop; Katja P Wolffenbuttel
Gonadal tumours and DSD.
Best practice & research. Clinical endocrinology & metabolism 2010;24(2):291-310.
2010: Joery Goede; Wilfried W M Hack; L M van der Voort-Doedens; Frank H Pierik; Leendert H J Looijenga; Karlijn Sijstermans
Testicular microlithiasis in boys and young men with congenital or acquired undescended (ascending) testis.
The Journal of urology 2010;183(4):1539-43.
2010: Susanne Weber; Dawid Eckert; Daniel Nettersheim; Ad J M Gillis; Sabine Schäfer; Peter Kuckenberg; Julia Ehlermann; Uwe Werling; Katharina Biermann; Leendert H J Looijenga; Hubert Schorle
Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance.
Biology of reproduction 2010;82(1):214-23.
2009: Anthony D Krentz; Mark W Murphy; Shinseog Kim; Matthew S Cook; Blanche Capel; Rui Zhu; Angabin Matin; Aaron L Sarver; Keith L Parker; Michael D Griswold; Leendert H J Looijenga; Vivian J Bardwell; David Zarkower
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(52):22323-8.
2009: Francesca Nuti; Paola Luciani; Eliana Marinari; Edit Erdei; Mihaly Bak; Cristiana Deledda; Fabiana Rosati; Benedetta Mazzinghi; Giovanna Danza; Hans Stoop; Leendert H J Looijenga; Alessandro Peri; Mario Serio; Csilla Krausz
Seladin-1 and testicular germ cell tumours: new insights into cisplatin responsiveness.
The Journal of pathology 2009;219(4):491-500.
2009: Remko Hersmus; Bertie de Leeuw; hans stoop; Pascal Bernard; HC van Doorn; Hennie T Brüggenwirth; Stenvert L S Drop; J Wolter Oosterhuis; Vincent R Harley; Leendert H J Looijenga
A novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma.
European journal of human genetics : EJHG 2009;17(12):1642-9.
2009: N J van Casteren; Jeroen de Jong; hans stoop; Ewout W Steyerberg; E W de Bekker-Grob; Gert R Dohle; J Wolter Oosterhuis; Leendert H J Looijenga
Evaluation of testicular biopsies for carcinoma in situ: immunohistochemistry is mandatory.
International journal of andrology 2009;32(6):666-74.
2009: Anja Buchheiser; Stefanie Liedtke; Leendert H J Looijenga; Gesine Kögler
Cord blood for tissue regeneration.
Journal of cellular biochemistry 2009;108(4):762-8.
2009: N J van Casteren; Leendert H J Looijenga; Gert R Dohle
Testicular microlithiasis and carcinoma in situ overview and proposed clinical guideline.
International journal of andrology 2009;32(4):279-87.
2009: Leendert H J Looijenga
Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insights.
The Journal of pathology 2009;218(2):146-62.
2009: Guido B van den Broek; Maarten Wildeman; Coen R N Rasch; Nicola Armstrong; Ed Schuuring; Adrian C Begg; Leendert H J Looijenga; Rik Scheper; Jacqueline E van der Wal; Lorian Menkema; Paulus van Diest; Alfons J M Balm; Marie-Louise F Van Velthuysen; Michiel van den Brekel
Molecular markers predict outcome in squamous cell carcinoma of the head and neck after concomitant cisplatin-based chemoradiation.
International journal of cancer. Journal international du cancer 2009;124(11):2643-50.
2009: Martine Cools; Leendert H J Looijenga; Katja P Wolffenbuttel; Sten L S Drop
Disorders of sex development: update on the genetic background, terminology and risk for the development of germ cell tumors.
World journal of pediatrics : WJP 2009;5(2):93-102.
2009: Friedemann Honecker; Hendrik Wermann; Frank Mayer; Ad J M Gillis; Hans Stoop; Ruud J L M van Gurp; Karin Oechsle; Ewout Steyerberg; Jörg Thomas Hartmann; Winand N M Dinjens; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(13):2129-36.
2009: Gert-Jan M van de Geijn; Remko Hersmus; Leendert H J Looijenga
Recent developments in testicular germ cell tumor research.
Birth defects research. Part C, Embryo today : reviews 2009;87(1):96-113.
2008: Csilla Krausz; Leendert H J Looijenga
Genetic aspects of testicular germ cell tumors.
Cell cycle (Georgetown, Tex.) 2008;7(22):3519-24.
2008: Remko Hersmus; Bertie H C G M de Leeuw; Katja P Wolffenbuttel; Stenvert L S Drop; J Wolter Oosterhuis; Martine Cools; Leendert H J Looijenga
New insights into type II germ cell tumor pathogenesis based on studies of patients with various forms of disorders of sex development (DSD).
Molecular and cellular endocrinology 2008;291(1-2):1-10.
2008: Stephanie Glaesener; Friedemann Honecker; Imke M Veltman; Ad J M Gillis; Tina Rohlfing; Thomas Streichert; Benjamin Otto; Tim H Brummendorf; Leendert H J Looijenga; Carsten Bokemeyer; Stefan Balabanov
Comparative proteome, transcriptome, and genome analysis of a gonadal and an extragonadal germ cell tumor cell line.
Journal of proteome research 2008;7(9):3890-9.
2008: Valerie Schumacher; Banu Gueler; Leendert H J Looijenga; Jan Ulrich Becker; Kerstin Amann; Rainer Engers; Joerg Dotsch; hans stoop; Wolfgang Schulz; Brigitte Royer-Pokora
Characteristics of testicular dysgenesis syndrome and decreased expression of SRY and SOX9 in Frasier syndrome.
Molecular reproduction and development 2008;75(9):1484-94.
2008: Niels J van Casteren; Gert R Dohle; Leendert H J Looijenga
Testicular microlithiasis is worrisome in a selected patient population.
Current opinion in urology 2008;18(4):436.
2008: Leendert H J Looijenga; Ad J M Gillis; J Wolter Oosterhuis
A pure triphasic testicular wilms tumor of primordial germ cell origin.
Urology 2008;72(1):232-3; author reply 233.
2008: Alan McIntyre; Duncan Gilbert; Neil Goddard; Leendert H J Looijenga; Janet Shipley
Genes, chromosomes and the development of testicular germ cell tumors of adolescents and adults.
Genes, chromosomes & cancer 2008;47(7):547-57.
2008: Niels J van Casteren; hans stoop; Gert R Dohle; Ronald de Wit; J Wolter Oosterhuis; Leendert H J Looijenga
Noninvasive detection of testicular carcinoma in situ in semen using OCT3/4.
European urology 2008;54(1):153-8.
2008: Remko Hersmus; N Kalfa; Bertie de Leeuw; hans stoop; J Wolter Oosterhuis; Ronald R de Krijger; Katja P Wolffenbuttel; Stenvert L S Drop; R A Veitia; M Fellous; F Jaubert; Leendert H J Looijenga
FOXL2 and SOX9 as parameters of female and male gonadal differentiation in patients with various forms of disorders of sex development (DSD).
The Journal of pathology 2008;215(1):31-8.
2008: Jeroen de Jong; hans stoop; Ad J M Gillis; Ruud van Gurp; Gert-Jan M van de Geijn; M de Boer; Remko Hersmus; Philippa Saunders; R A Anderson; J Wolter Oosterhuis; Leendert H J Looijenga
Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications.
The Journal of pathology 2008;215(1):21-30.
2008: S B Ng; M H Yong; L A Knight; V K M Lee; S Nadarajah; hans stoop; Leendert H J Looijenga
Gonadoblastoma-associated mixed germ cell tumour in 46,XY complete gonadal dysgenesis (Swyer syndrome): analysis of Y chromosomal genotype and OCT3/4 and TSPY expression profile.
Histopathology 2008;52(5):644-6.
2008: Jeroen de Jong; hans stoop; Ad J M Gillis; Remko Hersmus; Ruud van Gurp; Gert-Jan M van de Geijn; Ellen van Drunen; Berna Beverloo; Dominik Schneider; Jon K Sherlock; John Baeten; Sohei Kitazawa; Everardus J J van Zoelen; Kees E P van Roozendaal; J Wolter Oosterhuis; Leendert H J Looijenga
Further characterization of the first seminoma cell line TCam-2.
Genes, chromosomes & cancer 2008;47(3):185-96.
2008: Dawid Eckert; Katharina Biermann; Daniel Nettersheim; Ad J M Gillis; Klaus Steger; Hans-Martin Jäck; Annette M Müller; Leendert H J Looijenga; Hubert Schorle
Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors.
BMC developmental biology 2008;8():106.
2008: Jeroen de Jong; hans stoop; Martin van den Bent; Johan M Kros; J Wolter Oosterhuis; Leendert H J Looijenga
A 40-year-old woman with a progressive periventricular white matter lesion.
Brain pathology (Zurich, Switzerland) 2008;18(1):103-4, 142.
2008: Niels J van Casteren; Willem P A Boellaard; Gert R Dohle; R F A Weber; Marti C Kuizinga; hans stoop; Wolter J Oosterhuis; Leendert H J Looijenga
Heterogeneous distribution of ITGCNU in an adult testis: consequences for biopsy-based diagnosis.
International journal of surgical pathology 2008;16(1):21-4.
2007: Alan McIntyre; Brenda Summersgill; Yong-Jie Lu; E Missiaglia; S Kitazawa; J Wolter Oosterhuis; Leendert H J Looijenga; Janet Shipley
Genomic copy number and expression patterns in testicular germ cell tumours.
British journal of cancer 2007;97(12):1707-12.
2007: Leendert H J Looijenga; Ad J M Gillis; hans stoop; Remko Hersmus; J Wolter Oosterhuis
Chromosomes and expression in human testicular germ-cell tumors: insight into their cell of origin and pathogenesis.
Annals of the New York Academy of Sciences 2007;1120():187-214.
2007: Ad J M Gillis; hans stoop; Remko Hersmus; J Wolter Oosterhuis; Y Sun; C Chen; Simone M Guenther; Jon K Sherlock; Imke M Veltman; J Baeten; Peter van der Spek; Pedro A. De Alarcon; Leendert H J Looijenga
High-throughput microRNAome analysis in human germ cell tumours.
The Journal of pathology 2007;213(3):319-28.
2007: Claudia Zanazzi; Remko Hersmus; Imke M Veltman; Ad J M Gillis; Ellen van Drunen; Berna Beverloo; J P J J Hegmans; Marielle Verweij; Bart N Lambrecht; J Wolter Oosterhuis; Leendert H J Looijenga
Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines.
Genes, chromosomes & cancer 2007;46(10):895-908.
2007: Li Yunmin; Z Laura Tabatabai; Tin-Lap Lee; Shingo Hatakeyama; Chikara Ohyama; Wai-Yee Chan; Leendert H J Looijenga; Yun-Fai Chris Lau
The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.
Human pathology 2007;38(10):1470-81.
2007: Leendert H J Looijenga; Remko Hersmus; J Wolter Oosterhuis; Martine Cools; Stenvert L S Drop; Katja P Wolffenbuttel
Tumor risk in disorders of sex development (DSD).
Best practice & research. Clinical endocrinology & metabolism 2007;21(3):480-95.
2007: Jeroen de Jong; hans stoop; Ad J M Gillis; Ruud van Gurp; Ellen van Drunen; Berna Beverloo; Yun-Fai Chris Lau; Dominik Schneider; Jon K Sherlock; John Baeten; Shingo Hatakeyama; Chikara Ohyama; J Wolter Oosterhuis; Leendert H J Looijenga
JKT-1 is not a human seminoma cell line.
International journal of andrology 2007;30(4):350-65.
2007: J Wolter Oosterhuis; hans stoop; Friedemann Honecker; Leendert H J Looijenga
Why human extragonadal germ cell tumours occur in the midline of the body: old concepts, new perspectives.
International journal of andrology 2007;30(4):256-63; discussion 263-4.
2007: Leendert H J Looijenga; Ad J M Gillis; hans stoop; Remko Hersmus; J Wolter Oosterhuis
Relevance of microRNAs in normal and malignant development, including human testicular germ cell tumours.
International journal of andrology 2007;30(4):304-14; discussion 314-5.
2007: Leendert H J Looijenga; hans stoop; Remko Hersmus; Ad J M Gillis; J Wolter Oosterhuis
Genomic and expression profiling of human spermatocytic seminomas: pathogenetic implications.
International journal of andrology 2007;30(4):328-35; discussion 335-6.
2007: Martine Cools; Marjan Boter; Ruud van Gurp; hans stoop; Pino Poddighe; Yun-Fai Chris Lau; Stenvert L S Drop; Katja P Wolffenbuttel; Leendert H J Looijenga
Impact of the Y-containing cell line on histological differentiation patterns in dysgenetic gonads.
Clinical endocrinology 2007;67(2):184-92.
2007: Jeroen de Jong; Sannah Weeda; Ad J M Gillis; J Wolter Oosterhuis; Leendert H J Looijenga
Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors.
Oncology reports 2007;18(1):127-32.
2007: P Mathijs Voorhoeve; Carlos le Sage; Mariette Schrier; Ad J M Gillis; hans stoop; Remco Nagel; Ying-Poi Liu; Josyanne van Duijse; Jarno Drost; Alexander Griekspoor; Eitan Zlotorynski; Norikazu Yabuta; Gabriella De Vita; Hiroshi Nojima; Leendert H J Looijenga; Reuven Agami
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.
Advances in experimental medicine and biology 2007;604():17-46.
2007: Leendert H J Looijenga; J Wolter Oosterhuis
Are all testicular seminomas of animals in fact spermatocytic seminomas?
Veterinary pathology 2007;44(1):126.
2007: Liang Cheng; Ming-Tse Sung; Paolo Cossu Rocca; Timothy D Jones; Gregory T MacLennan; J De Jong; Antonio Lopez-Beltran; Rodolfo Montironi; Leendert H J Looijenga
OCT4: biological functions and clinical applications as a marker of germ cell neoplasia.
The Journal of pathology 2007;211(1):1-9.
2006: Jeroen de Jong; Leendert H J Looijenga
Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future.
Critical reviews in oncogenesis 2006;12(3-4):171-203.
2006: Martine Cools; Stenvert L S Drop; Katja P Wolffenbuttel; J Wolter Oosterhuis; Leendert H J Looijenga
Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiers.
Endocrine reviews 2006;27(5):468-84.
2006: Martine Cools; hans stoop; Anne-Marie F Kersemaekers; Stenvert L S Drop; Katja P Wolffenbuttel; Jean-Pierre Bourguignon; Jolanta Slowikowska-Hilczer; Krzysztof Kula; Sultana M H Faradz; J Wolter Oosterhuis; Leendert H J Looijenga
Gonadoblastoma arising in undifferentiated gonadal tissue within dysgenetic gonads.
The Journal of clinical endocrinology and metabolism 2006;91(6):2404-13.
2006: Paul C M S Verhagen; Petra W van Duijn; Karin G Hermans; Leendert H J Looijenga; Ruud van Gurp; hans stoop; Theo Van der Kwast; Jan Trapman
The PTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion.
The Journal of pathology 2006;208(5):699-707.
2006: P Mathijs Voorhoeve; Carlos le Sage; Mariette Schrier; Ad J M Gillis; hans stoop; Remco Nagel; Ying-Poi Liu; Josyanne van Duijse; Jarno Drost; Alexander Griekspoor; Eitan Zlotorynski; Norikazu Yabuta; Gabriella De Vita; Hiroshi Nojima; Leendert H J Looijenga; Reuven Agami
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.
Cell 2006;124(6):1169-81.
2006: Daniella Herszfeld; Ernst Wolvetang; Emma Langton-Bunker; Tung-Liang Chung; Adam A Filipczyk; Souheir Houssami; Pegah Jamshidi; Karen Koh; Andrew L Laslett; Anna Michalska; Linh Nguyen; Benjamin E Reubinoff; Irene Tellis; Jonathan M Auerbach; Carol J Ording; Leendert H J Looijenga; Martin F Pera
CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells.
Nature biotechnology 2006;24(3):351-7.
2006: Friedemann Honecker; hans stoop; Frank Mayer; Carsten Bokemeyer; Diego H Castrillon; Yun-Fai Chris Lau; Leendert H J Looijenga; J Wolter Oosterhuis
Germ cell lineage differentiation in non-seminomatous germ cell tumours.
The Journal of pathology 2006;208(3):395-400.
2006: Leendert H J Looijenga; Remko Hersmus; Ad J M Gillis; Rolph Pfundt; hans stoop; Ruud van Gurp; Joris Veltman; Berna Beverloo; Ellen van Drunen; Ad Geurts van Kessel; Renee Reijo Pera; Dominik Schneider; Brenda Summersgill; Janet Shipley; Alan McIntyre; Peter van der Spek; Eric F P M Schoenmakers; J Wolter Oosterhuis
Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene.
Cancer research 2006;66(1):290-302.
2006: Martine Cools; Friedemann Honecker; hans stoop; Joris D Veltman; Ronald R de Krijger; Ewout W Steyerberg; Katja P Wolffenbuttel; Carsten Bokemeyer; Yun-Fai Chris Lau; Stenvert L S Drop; Leendert H J Looijenga
Maturation delay of germ cells in fetuses with trisomy 21 results in increased risk for the development of testicular germ cell tumors.
Human pathology 2006;37(1):101-11.
2006: Graham Bignell; Raffaella Smith; Chris Hunter; Philip Stephens; Helen Davies; Chris Greenman; Jon Teague; Adam Butler; Sarah Edkins; Claire Stevens; Sarah O'Meara; Adrian Parker; Tim Avis; Syd Barthorpe; Lisa Brackenbury; Gemma Buck; Jody Clements; Jennifer Cole; Ed Dicks; Ken Edwards; Simon Forbes; Matthew Gorton; Kristian Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jonathon Hinton; David Jones; Vivienne Kosmidou; Ross Laman; Richard Lugg; Andrew Menzies; Janet Perry; Robert Petty; Keiran Raine; Rebecca Shepherd; Alexandra Small; Helen Solomon; Yvonne Stephens; Calli Tofts; Jennifer Varian; Anthony Webb; Sofie West; Sara Caroline Widaa; Andy Yates; Ad J M Gillis; hans stoop; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga; P Andrew Futreal; Richard Wooster; Michael R Stratton
Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
Genes, chromosomes & cancer 2006;45(1):42-6.
2005: Katherine L Nathanson; Peter Kanetsky; Rachel Hawes; David J Vaughn; Richard Letrero; Kathy Tucker; Michael Friedlander; Kelly-Anne Phillips; David Hogg; Michael A S Jewett; Radka Lohynska; Gedske Daugaard; Stéphane Richard; Agnés Chompret; Catherine Bonaïti-Pellié; Axel Heidenreich; Edith Olah; Lajos Geczi; Istvan Bodrogi; Wilma J Ormiston; Peter A Daly; J Wolter Oosterhuis; Ad J M Gillis; Leendert H J Looijenga; Parry Guilford; Sophie D Fosså; Ketil Heimdal; Sergei A Tjulandin; Ludmila Liubchenko; Hans Stoll; Walter Weber; Matthew Rudd; Robert Huddart; Gillian P Crockford; David Forman; D Timothy Oliver; Lawrence Einhorn; Barbara L Weber; Joan Kramer; Mary McMaster; Mark H Greene; Malcolm Pike; Victoria Cortessis; Chu Chen; Stephen M Schwartz; Tim BISHOP; Douglas F Easton; Michael R Stratton; Elizabeth A Rapley
The Y deletion gr/gr and susceptibility to testicular germ cell tumor.
American journal of human genetics 2005;77(6):1034-43.
2005: Adam H Hart; Lynne Hartley; Karen Parker; Marilyn Ibrahim; Leendert H J Looijenga; Marija Pauchnik; Chung Wo Chow; Lorraine Robb
The pluripotency homeobox gene NANOG is expressed in human germ cell tumors.
Cancer 2005;104(10):2092-8.
2005: Sonja Sievers; Katayoun Alemazkour; Susanne Zahn; Elizabeth J. Perlman; Ad J M Gillis; Leendert H J Looijenga; Ulrich Göbel; Dominik Schneider
IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylation-sensitive single-nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development.
Genes, chromosomes & cancer 2005;44(3):256-64.
2005: Alan McIntyre; Brenda Summersgill; Beata Grygalewicz; Ad J M Gillis; J Stoop; Ruud van Gurp; Nening Dennis; Cyril Fisher; Robert A Huddart; Colin Cooper; Jeremy Clark; J Wolter Oosterhuis; Leendert H J Looijenga; Janet Shipley
Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults.
Cancer research 2005;65(18):8085-9.
2005: Helen Davies; Chris Hunter; Raffaella Smith; Philip Stephens; Chris Greenman; Graham Bignell; Jon Teague; Adam Butler; Sarah Edkins; Claire Stevens; Adrian Parker; Sarah O'Meara; Tim Avis; Syd Barthorpe; Lisa Brackenbury; Gemma Buck; Jody Clements; Jennifer Cole; Ed Dicks; Ken Edwards; Simon Forbes; Matthew Gorton; Kristian Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jonathon Hinton; David Jones; Vivienne Kosmidou; Ross Laman; Richard Lugg; Andrew Menzies; Janet Perry; Robert Petty; Keiran Raine; Rebecca Shepherd; Alexandra Small; Helen Solomon; Yvonne Stephens; Calli Tofts; Jennifer Varian; Anthony Webb; Sofie West; Sara Caroline Widaa; Andrew Yates; Francis Brasseur; Colin S Cooper; Adrienne M Flanagan; Anthony Green; Maggie Knowles; Suet Y Leung; Leendert H J Looijenga; Bruce Malkowicz; Marco A Pierotti; Bin Tean Teh; Siu T Yuen; Sunil R Lakhani; Douglas F Easton; Barbara L Weber; Peter Goldstraw; Andrew G Nicholson; Richard Wooster; Michael R Stratton; P Andrew Futreal
Somatic mutations of the protein kinase gene family in human lung cancer.
Cancer research 2005;65(17):7591-5.
2005: Martine Cools; Koen van Aerde; Anne-Marie F Kersemaekers; Marjan Boter; Stenvert L S Drop; Katja P Wolffenbuttel; Ewout W Steyerberg; J Wolter Oosterhuis; Leendert H J Looijenga
Morphological and immunohistochemical differences between gonadal maturation delay and early germ cell neoplasia in patients with undervirilization syndromes.
The Journal of clinical endocrinology and metabolism 2005;90(9):5295-303.
2005: Imke M Veltman; Joris Veltman; Irene M Janssen; Christina A Hulsbergen-van de Kaa; Wolter Oosterhuis; Dominik Schneider; hans stoop; Ad Gillis; Susanne Zahn; Leendert H J Looijenga; Ulrich Göbel; Ad Geurts van Kessel
Identification of recurrent chromosomal aberrations in germ cell tumors of neonates and infants using genomewide array-based comparative genomic hybridization.
Genes, chromosomes & cancer 2005;43(4):367-76.
2005: Imke M Veltman; Lilian A Vreede; Jinke Cheng; Leendert H J Looijenga; Bert Janssen; Eric F P M Schoenmakers; Edward T H Yeh; Ad Geurts van Kessel
Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).
Human molecular genetics 2005;14(14):1955-63.
2005: Philip Stephens; Sarah Edkins; Helen Davies; Chris Greenman; Charles Cox; Chris Hunter; Graham Bignell; Jon Teague; Raffaella Smith; Claire Stevens; Sarah O'Meara; Adrian Parker; Patrick Tarpey; Tim Avis; Andy Barthorpe; Lisa Brackenbury; Gemma Buck; Adam Butler; Jody Clements; Jennifer Cole; Ed Dicks; Ken Edwards; Simon Forbes; Matthew Gorton; Kristian Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jonathon Hinton; David Jones; Vivienne Kosmidou; Ross Laman; Richard Lugg; Andrew Menzies; Janet Perry; Robert Petty; Keiran Raine; Rebecca Shepherd; Alexandra Small; Helen Solomon; Yvonne Stephens; Calli Tofts; Jennifer Varian; Anthony Webb; Sofie West; Sara Caroline Widaa; Andrew Yates; Francis Brasseur; Colin S Cooper; Adrienne M Flanagan; Anthony Green; Maggie Knowles; Suet Y Leung; Leendert H J Looijenga; Bruce Malkowicz; Marco A Pierotti; Bin Tean Teh; Siu T Yuen; Andrew G Nicholson; Sunil Lakhani; Douglas F Easton; Barbara L Weber; Michael R Stratton; P Andrew Futreal; Richard Wooster
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.
Nature genetics 2005;37(6):590-2.
2005: Jeroen de Jong; hans stoop; Gert R Dohle; Chris H Bangma; Mike Kliffen; Joost W J van Esser; Martin J van den Bent; Johan M Kros; J Wolter Oosterhuis; Leendert H J Looijenga
Diagnostic value of OCT3/4 for pre-invasive and invasive testicular germ cell tumours.
The Journal of pathology 2005;206(2):242-9.
2005: hans stoop; Friedemann Honecker; Martine Cools; Ronald R de Krijger; Carsten Bokemeyer; Leendert H J Looijenga
Differentiation and development of human female germ cells during prenatal gonadogenesis: an immunohistochemical study.
Human reproduction (Oxford, England) 2005;20(6):1466-76.
2005: Anne-Marie F Kersemaekers; Friedemann Honecker; hans stoop; Martine Cools; Michel Molier; Katja P Wolffenbuttel; Carsten Bokemeyer; Yunmin Li; Yun-Fai Chris Lau; J Wolter Oosterhuis; Leendert H J Looijenga
Identification of germ cells at risk for neoplastic transformation in gonadoblastoma: an immunohistochemical study for OCT3/4 and TSPY.
Human pathology 2005;36(5):512-21.
2005: Dominique Marcus-Soekarman; G Hamers; A L M Mulder; Jos P M Offermans; Jos Offermans; J J M Engelen; J C M van Lent-Albrechts; S G F Robben; Sabine M P F de Muinck Keizer-Schrama; K P Wolffenbuttel; Leendert H J Looijenga; J W Oosterhuis; C T R M Schrander-Stumpel; JG Nijhuis
Sonographic genital ambiguity in a fetus due to a mosaic 45,X/46,X,idic(Y)(qter-p11.32::p11.32-qter) karyotype.
Prenatal diagnosis 2005;25(4):279-82.
2005: J Wolter Oosterhuis; Leendert H J Looijenga
Testicular germ-cell tumours in a broader perspective.
Nature reviews. Cancer 2005;5(3):210-22.
2005: Elize M Biemond-ter Stege; Johan M Kros; Hein G de Bruin; Roelien H Enting; Irene van Heuvel; Leendert H J Looijenga; Carin D D van der Rijt; Peter A E Sillevis Smitt; Martin J van den Bent
Successful treatment of low-grade oligodendroglial tumors with a chemotherapy regimen of procarbazine, lomustine, and vincristine.
Cancer 2005;103(4):802-9.
2004: Alan McIntyre; Brenda Summersgill; Osman Jafer; Sandrine Rodriguez; Gaetano Zafarana; J Wolter Oosterhuis; Ad J M Gillis; Leendert H J Looijenga; Colin Cooper; Robert A Huddart; Jeremy Clark; Janet Shipley
Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones.
Oncogene 2004;23(56):9142-7.
2004: Walter Verbeek; Hans-Jürgen Schulten; Matthias Sperling; Jens Tiesmeier; hans stoop; Winand N M Dinjens; Leendert H J Looijenga; Bernhard Wörmann; László Füzesi; Konrad Donhuijsen
Rectal adenocarcinoma with choriocarcinomatous differentiation: clinical and genetic aspects.
Human pathology 2004;35(11):1427-30.
2004: Friedemann Honecker; Anne-Marie F Kersemaekers; Michel Molier; Pascale C van Weeren; hans stoop; Ronald R de Krijger; Katja P Wolffenbuttel; Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Involvement of E-cadherin and beta-catenin in germ cell tumours and in normal male fetal germ cell development.
The Journal of pathology 2004;204(2):167-74.
2004: Philip Stephens; Chris Hunter; Graham Bignell; Sarah Edkins; Helen Davies; Jon Teague; Claire Stevens; Sarah O'Meara; Raffaella Smith; Adrian Parker; Andy Barthorpe; Matthew Blow; Lisa Brackenbury; Adam Butler; Oliver Clarke; Jennifer Cole; Ed Dicks; Angus Dike; Anja Drozd; Ken Edwards; Simon Forbes; Rebecca Foster; Kristian Gray; Chris Greenman; Kelly Halliday; Katy Hills; Vivienne Kosmidou; Richard Lugg; Andy Menzies; Janet Perry; Robert Petty; Keiran Raine; Lewis Ratford; Rebecca Shepherd; Alexandra Small; Yvonne Stephens; Calli Tofts; Jennifer Varian; Sofie West; Sara Caroline Widaa; Andrew Yates; Francis Brasseur; Colin S Cooper; Adrienne M Flanagan; Margaret Knowles; Suet Y Leung; David N Louis; Leendert H J Looijenga; Bruce Malkowicz; Marco A Pierotti; Bin Tean Teh; Georgia Chenevix-Trench; Barbara L Weber; Siu T Yuen; Grace Harris; Peter Goldstraw; Andrew G Nicholson; P Andrew Futreal; Richard Wooster; Michael R Stratton
Lung cancer: intragenic ERBB2 kinase mutations in tumours.
Nature 2004;431(7008):525-6.
2004: Paul W Schenk; hans stoop; Carsten Bokemeyer; Frank Mayer; Gerrit Stoter; J Wolter Oosterhuis; Erik A C Wiemer; Leendert H J Looijenga; Kees Nooter
Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.
Neoplasia (New York, N.Y.) 2004;6(4):297-301.
2004: Friedemann Honecker; hans stoop; Ronald R de Krijger; Yun-Fai Chris Lau; Carsten Bokemeyer; Leendert H J Looijenga
Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells.
The Journal of pathology 2004;203(3):849-57.
2004: E A Rapley; S Hockley; W Warren; L Johnson; R Huddart; G Crockford; D Forman; M G Leahy; D T Oliver; K Tucker; M Friedlander; K-A Phillips; D Hogg; M A S Jewett; R Lohynska; G Daugaard; S Richard; A Heidenreich; L Geczi; I Bodrogi; E Olah; W J Ormiston; P A Daly; Leendert H J Looijenga; P Guilford; N Aass; S D Fosså; K Heimdal; S A Tjulandin; L Liubchenko; H Stoll; W Weber; L Einhorn; B L Weber; M McMaster; M H Greene; Tim BISHOP; D Easton; M R Stratton
Somatic mutations of KIT in familial testicular germ cell tumours.
British journal of cancer 2004;90(12):2397-401.
2004: Friedemann Honecker; J Wolter Oosterhuis; Frank Mayer; Jörg Thomas Hartmann; Carsten Bokemeyer; Leendert H J Looijenga
New insights into the pathology and molecular biology of human germ cell tumors.
World journal of urology 2004;22(1):15-24.
2004: Leendert H J Looijenga; J Wolter Oosterhuis
Clinical value of the X chromosome in testicular germ-cell tumours.
Lancet 2004;363(9402):6-8.
2004: Carlos A de Gouveia Brazao; Frank H Pierik; J Wolter Oosterhuis; Gert R Dohle; Leendert H J Looijenga; R F A Weber
Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men.
The Journal of urology 2004;171(1):158-60.
2004: Bas W D de Jong; Carlos A de Gouveia Brazao; hans stoop; Katja P Wolffenbuttel; J Wolter Oosterhuis; Gerwin Puppels; R F A Weber; Leendert H J Looijenga; dirk kok
Raman spectroscopic analysis identifies testicular microlithiasis as intratubular hydroxyapatite.
The Journal of urology 2004;171(1):92-6.
2003: Leendert H J Looijenga; Hubert P J C de Leeuw; Monique van Oorschot; Ruud van Gurp; hans stoop; Ad J M Gillis; Carlos A de Gouveia Brazao; R F A Weber; Wim J Kirkels; Thamar B van Dijk; Marieke von Lindern; Peter J M Valk; Geczy Lajos; Edit Olah; Jahn M Nesland; Sophie D Fosså; J Wolter Oosterhuis
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors.
Cancer research 2003;63(22):7674-8.
2003: Gaetano Zafarana; Beata Grygalewicz; Ad J M Gillis; Lisenka E L M Vissers; Walter van de Vliet; Ruud van Gurp; hans stoop; Maria Debiec-Rychter; J Wolter Oosterhuis; Ad Geurts van Kessel; Eric F P M Schoenmakers; Leendert H J Looijenga; Joris Veltman
12p-amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.
Oncogene 2003;22(48):7695-701.
2003: Friedemann Honecker; Frank Mayer; hans stoop; J Wolter Oosterhuis; Sandra Koch; Carsten Bokemeyer; Leendert H J Looijenga
Xeroderma pigmentosum group a protein and chemotherapy resistance in human germ cell tumors.
Laboratory investigation; a journal of technical methods and pathology 2003;83(10):1489-95.
2003: Sophie D Fosså; Nina Aass; Arne Heilo; G Daugaard; N E Skakkebaek; Anna E Stenwig; Jahn M Nesland; Leendert H J Looijenga; J W Oosterhuis
Testicular carcinoma in situ in patients with extragonadal germ-cell tumours: the clinical role of pretreatment biopsy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(9):1412-8.
2003: Frank Mayer; hans stoop; Subrata Sen; Carsten Bokemeyer; J Wolter Oosterhuis; Leendert H J Looijenga
Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes.
Oncogene 2003;22(25):3859-66.
2003: Frank Mayer; Friedemann Honecker; Leendert H J Looijenga; Carsten Bokemeyer
Towards an understanding of the biological basis of response to cisplatin-based chemotherapy in germ-cell tumors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(6):825-32.
2003: Leendert H J Looijenga; hans stoop; Hubert P J C de Leeuw; Carlos A de Gouveia Brazao; Ad J M Gillis; Kees E P van Roozendaal; Everardus J J van Zoelen; R F A Weber; Katja P Wolffenbuttel; Herman van Dekken; Friedemann Honecker; Carsten Bokemeyer; Elizabeth J. Perlman; Dominik Schneider; Juha Kononen; Guido Sauter; J Wolter Oosterhuis
POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors.
Cancer research 2003;63(9):2244-50.
2003: Sandrine Rodriguez; Osman Jafer; H Goker; Brenda Summersgill; Gaetano Zafarana; Ad J M Gillis; Ruud van Gurp; J Wolter Oosterhuis; Yong-Jie Lu; Robert A Huddart; C S Cooper; Jeremy Clark; Leendert H J Looijenga; Janet Shipley
Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1.
Oncogene 2003;22(12):1880-91.
2003: Martin J van den Bent; Leendert H J Looijenga; Karin Langenberg; Winand N M Dinjens; Wilfried J Graveland; Ludo Uytdewilligen; Peter A E Sillevis Smitt; Robert B Jenkins; Johan M Kros
Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features.
Cancer 2003;97(5):1276-84.
2003: Frank Mayer; hans stoop; George L Scheffer; Rik J Scheper; J Wolter Oosterhuis; Leendert H J Looijenga; Carsten Bokemeyer
Molecular determinants of treatment response in human germ cell tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):767-73.
2003: J Wolter Oosterhuis; Leendert H J Looijenga
Current views on the pathogenesis of testicular germ cell tumours and perspectives for future research: highlights of the 5th Copenhagen Workshop on Carcinoma in situ and Cancer of the Testis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):280-9.
2003: Leendert H J Looijenga; Gaetano Zafarana; Beata Grygalewicz; Brenda Summersgill; Maria Debiec-Rychter; Joris Veltman; Eric F P M Schoenmakers; Sandrine Rodriguez; Osman Jafer; Jeremy Clark; Ad Geurts van Kessel; Janet Shipley; Ruud van Gurp; Ad J M Gillis; J Wolter Oosterhuis
Role of gain of 12p in germ cell tumour development.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):161-71; discussion 172-3.
2003: Imke M Veltman; Marga Schepens; Leendert H J Looijenga; Louise C Strong; Ad Geurts van Kessel
Germ cell tumours in neonates and infants: a distinct subgroup?
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):152-60; discussion 160.
2003: J Wolter Oosterhuis; Anne-Marie F Kersemaekers; Grete Krag Jacobsen; A Timmer; Ewout W Steyerberg; Michel Molier; Pascale C van Weeren; hans stoop; Leendert H J Looijenga
Morphology of testicular parenchyma adjacent to germ cell tumours. An interim report.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):32-40; discussion 41-2.
2002: Leendert H J Looijenga; J Wolter Oosterhuis
Pathobiology of testicular germ cell tumors: views and news.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2002;24(5):263-79.
2002: Christian Kollmannsberger; Frank Mayer; Harald Pressler; S Koch; Lothar Kanz; J W Oosterhuis; Leendert H J Looijenga; Carsten Bokemeyer
Absence of c-KIT and members of the epidermal growth factor receptor family in refractory germ cell cancer.
Cancer 2002;95(2):301-8.
2002: Imke M Veltman; Martien van Asseldonk; Marga Schepens; hans stoop; Leendert H J Looijenga; Cokkie H Wouters; Lutgarde Govaerts; Ron Suijkerbuijk; Ad Geurts van Kessel
A novel case of infantile sacral teratoma and a constitutional t(12;15)(q13;q25) pat.
Cancer genetics and cytogenetics 2002;136(1):17-22.
2002: Dan Qiao; Anne-Marie Zeeman; Wei Deng; Leendert H J Looijenga; Haifan Lin
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas.
Oncogene 2002;21(25):3988-99.
2002: Frank Mayer; Ad J M Gillis; Winand N M Dinjens; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Microsatellite instability of germ cell tumors is associated with resistance to systemic treatment.
Cancer research 2002;62(10):2758-60.
2002: Camilla Palumbo; Kees E P van Roozendaal; Ad J M Gillis; Ruud van Gurp; Hannie de Munnik; J Wolter Oosterhuis; Everardus J J van Zoelen; Leendert H J Looijenga
Expression of the PDGF alpha-receptor 1.5 kb transcript, OCT-4, and c-KIT in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms.
The Journal of pathology 2002;196(4):467-77.
2002: Anne-Marie F Kersemaekers; Pascale C van Weeren; J Wolter Oosterhuis; Leendert H J Looijenga
Involvement of the Fas/FasL pathway in the pathogenesis of germ cell tumours of the adult testis.
The Journal of pathology 2002;196(4):423-9.
2002: Gaetano Zafarana; Ad J M Gillis; Ruud van Gurp; Per Olsson; Fons Elstrodt; hans stoop; José Luis Millán; J Wolter Oosterhuis; Leendert H J Looijenga
Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
Cancer research 2002;62(6):1822-31.
2002: Anne-Marie F Kersemaekers; Frank Mayer; Michel Molier; Pascale C van Weeren; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Role of P53 and MDM2 in treatment response of human germ cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1551-61.
2002: Anne-Marie Zeeman; hans stoop; Marjan Boter; Ad J M Gillis; Diego H Castrillon; J Wolter Oosterhuis; Leendert H J Looijenga
VASA is a specific marker for both normal and malignant human germ cells.
Laboratory investigation; a journal of technical methods and pathology 2002;82(2):159-66.
2001: hans stoop; Ruud van Gurp; Ronald R de Krijger; A Geurts van Kessel; B Köberle; Wolter Oosterhuis; Leendert H J Looijenga
Reactivity of germ cell maturation stage-specific markers in spermatocytic seminoma: diagnostic and etiological implications.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):919-28.
2001: Bart A Westerman; Ankie Poutsma; Leendert H J Looijenga; Dorine Wouters; Inge J van Wijk; Cees B M Oudejans
The Human Achaete Scute Homolog 2 gene contains two promotors, generating overlapping transcripts and encoding two proteins with different nuclear localization.
Placenta 2001;22(6):511-8.
2001: Carsten Bokemeyer; Ad J M Gillis; K Pompe; Frank Mayer; Bernd Metzner; Norbert Schleucher; Jan Schleicher; G Pflugrad-Jauch; J W Oosterhuis; Lothar Kanz; Leendert H J Looijenga
Clinical impact of germ cell tumor cells in apheresis products of patients receiving high-dose chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(12):3029-36.
2000: Carla Rosenberg; Ruud van Gurp; Eric Geelen; J Wolter Oosterhuis; Leendert H J Looijenga
Overrepresentation of the short arm of chromosome 12 is related to invasive growth of human testicular seminomas and nonseminomas.
Oncogene 2000;19(51):5858-62.
2000: Sietske A Riemersma; Ekaterina S. Jordanova; R F Schop; Katja Philippo; Leendert H J Looijenga; Ed Schuuring; Philip M Kluin
Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites.
Blood 2000;96(10):3569-77.
2000: H Roelofs; MC Mostert; K Pompe; Gaetano Zafarana; M van Oorschot; Ruud van Gurp; Ad J M Gillis; hans stoop; Berna Beverloo; J Wolter Oosterhuis; Carsten Bokemeyer; Leendert H J Looijenga
Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis.
The American journal of pathology 2000;157(4):1155-66.
2000: SW Faulkner; D A Leigh; J W Oosterhuis; H Roelofs; Leendert H J Looijenga; ML Friedlander
Allelic losses in carcinoma in situ and testicular germ cell tumours of adolescents and adults: evidence suggestive of the linear progression model.
British journal of cancer 2000;83(6):729-36.
2000: MC Mostert; Carla Rosenberg; hans stoop; M Schuyer; A Timmer; Wolter Oosterhuis; Leendert H J Looijenga
Comparative genomic and in situ hybridization of germ cell tumors of the infantile testis.
Laboratory investigation; a journal of technical methods and pathology 2000;80(7):1055-64.
2000: Leendert H J Looijenga; Carla Rosenberg; Ruud van Gurp; Eric Geelen; Jannie van Echten-Arends; Bauke de Jong; MC Mostert; J Wolter Oosterhuis
Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminoma.
The Journal of pathology 2000;191(2):187-92.
2000: M Rørth; E Rajpert-De Meyts; L Andersson; K P Dieckmann; S D Fosså; K M Grigor; W F Hendry; Harry W Herr; Leendert H J Looijenga; J W Oosterhuis; N E Skakkebaek
Carcinoma in situ in the testis.
Scandinavian journal of urology and nephrology. Supplementum 2000;(205):166-86.
1999: Leendert H J Looijenga; H de Munnik; J W Oosterhuis
A molecular model for the development of germ cell cancer.
International journal of cancer. Journal international du cancer 1999;83(6):809-14.
1999: Carla Rosenberg; TB Schut; MC Mostert; Hans J Tanke; Anton K Raap; J Wolter Oosterhuis; Leendert H J Looijenga
Chromosomal gains and losses in testicular germ cell tumors of adolescents and adults investigated by a modified comparative genomic hybridization approach.
Laboratory investigation; a journal of technical methods and pathology 1999;79(12):1447-51.
1999: H Roelofs; Thomas Manes; T Janszen; José Luis Millán; J Wolter Oosterhuis; Leendert H J Looijenga
Heterogeneity in alkaline phosphatase isozyme expression in human testicular germ cell tumours: An enzyme-/immunohistochemical and molecular analysis.
The Journal of pathology 1999;189(2):236-44.
1999: E M van Schothorst; S Mohkamsing; Ruud van Gurp; J Wolter Oosterhuis; P T van der Saag; Leendert H J Looijenga
Lack of Bcl10 mutations in testicular germ cell tumours and derived cell lines.
British journal of cancer 1999;80(10):1571-4.
1999: Herman Burger; Kees Nooter; Antonius W M Boersma; KE van Wingerden; Leendert H J Looijenga; A G Jochemsen; Gerrit Stoter
Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines.
International journal of cancer. Journal international du cancer 1999;81(4):620-8.
1999: Leendert H J Looijenga; J Wolter Oosterhuis
Pathogenesis of testicular germ cell tumours.
Reviews of reproduction 1999;4(2):90-100.
1999: Leendert H J Looijenga; Ad J M Gillis; AJ Verkerk; W L van Putten; J Wolter Oosterhuis
Heterogeneous X inactivation in trophoblastic cells of human full-term female placentas.
American journal of human genetics 1999;64(5):1445-52.
1998: Carla Rosenberg; MC Mostert; TB Schut; Martijn Van de Pol; Jannie van Echten; Bauke de Jong; Anton K Raap; Hans J Tanke; J Wolter Oosterhuis; Leendert H J Looijenga
Chromosomal constitution of human spermatocytic seminomas: comparative genomic hybridization supported by conventional and interphase cytogenetics.
Genes, chromosomes & cancer 1998;23(4):286-91.
1998: C E van Roozendaal; Ad J M Gillis; Jan G M Klijn; B van Ooijen; CJ Claassen; A M Eggermont; SC Henzen-Logmans; J W Oosterhuis; John A Foekens; Leendert H J Looijenga
Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures.
FEBS letters 1998;437(1-2):107-11.
1998: H Roelofs; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga
Detection of human endogenous retrovirus type K-specific transcripts in testicular parenchyma and testicular germ cell tumors of adolescents and adults: clinical and biological implications.
The American journal of pathology 1998;153(4):1277-82.
1998: E Kopf; Osaat Bibi; Suhail Ayesh; Mark L Tykocinski; K Vitner; Leendert H J Looijenga; Nathan de Groot; Abraham Hochberg
The effect of retinoic acid on the activation of the human H19 promoter by a 3' downstream region.
FEBS letters 1998;432(3):123-7.
1998: MC Mostert; AJ Verkerk; Martijn Van de Pol; Jim Heighway; P Marynen; Carla Rosenberg; A G van Kessel; Jannie van Echten; Bauke de Jong; J Wolter Oosterhuis; Leendert H J Looijenga
Identification of the critical region of 12p over-representation in testicular germ cell tumors of adolescents and adults.
Oncogene 1998;16(20):2617-27.
1998: AA Caricasole; Ron van Schaik; Laura M Zeinstra; CD Wierikx; Ruud van Gurp; M van den Pol; Leendert H J Looijenga; J Wolter Oosterhuis; M F Pera; A Ward; D de Bruijn; Piet Kramer; Frank de Jong; AJ van den Eijnden-van Raaij
Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours.
Oncogene 1998;16(1):95-103.
1998: J Wolter Oosterhuis; Ad J M Gillis; C E van Roozendaal; Everardus J J van Zoelen; Leendert H J Looijenga
The platelet-derived growth factor alpha-receptor 1.5 kb transcript: target for molecular detection of testicular germ cell tumours of adolescents and adults.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):207-13; discussion 213-5.
1998: Leendert H J Looijenga; AJ Verkerk; MC Dekker; Ruud van Gurp; Ad J M Gillis; J Wolter Oosterhuis
Genomic imprinting in testicular germ cell tumours.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):187-95; discussion 196-7.
1997: Carla Rosenberg; TB Schut; MC Mostert; Hans J Tanke; Anton K Raap; J Wolter Oosterhuis; Leendert H J Looijenga
Comparative genomic hybridization in hypotriploid/hyperdiploid tumors.
Cytometry 1997;29(2):113-21.
1997: Nisar P Malek; Jochen Casper; Leendert H J Looijenga; T Strohmeyer; Hans-Joachim Schmoll; Alfred Nordheim; R Janknecht
Quantification of additional short arms of chromosome 12 in germ cell tumours using the polymerase chain reaction.
European journal of cancer (Oxford, England : 1990) 1997;33(9):1488-94.
1997: Leendert H J Looijenga; Ad J M Gillis; Ruud van Gurp; AJ Verkerk; J Wolter Oosterhuis
X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status.
The American journal of pathology 1997;151(2):581-90.
1997: Barbie M Machiels; Frans C S Ramaekers; Helma J H Kuijpers; J S Groenewoud; J W Oosterhuis; Leendert H J Looijenga
Nuclear lamin expression in normal testis and testicular germ cell tumours of adolescents and adults.
The Journal of pathology 1997;182(2):197-204.
1997: J Wolter Oosterhuis; Leendert H J Looijenga; Jannie van Echten; Bauke de Jong
Chromosomal constitution and developmental potential of human germ cell tumors and teratomas.
Cancer genetics and cytogenetics 1997;95(1):96-102.
1997: Bauke de Jong; Jannie van Echten; Leendert H J Looijenga; Ad Geurts van Kessel; J Wolter Oosterhuis
Cytogenetics of the progression of adult testicular germ cell tumors.
Cancer genetics and cytogenetics 1997;95(1):88-95.
1997: Leendert H J Looijenga; AJ Verkerk; N De Groot; Abraham Hochberg; J Wolter Oosterhuis
H19 in normal development and neoplasia.
Molecular reproduction and development 1997;46(3):419-39.
1997: AJ Verkerk; Ilana Ariel; MC Dekker; T Schneider; Ruud van Gurp; N de Groot; Ad J M Gillis; J Wolter Oosterhuis; Abraham Hochberg; Leendert H J Looijenga
Unique expression patterns of H19 in human testicular cancers of different etiology.
Oncogene 1997;14(1):95-107.
1997: Ron van Schaik; CD Wierikx; Leendert H J Looijenga; J Wolter Oosterhuis; Frank de Jong
Human testicular germ cell tumours express inhibin subunits, activin receptors and follistatin mRNAs.
British journal of cancer 1997;76(9):1191-8.
1997: Ad J M Gillis; AJ Verkerk; MC Dekker; Ruud van Gurp; J Wolter Oosterhuis; Leendert H J Looijenga
Methylation similarities of two CpG sites within exon 5 of human H19 between normal tissues and testicular germ cell tumours of adolescents and adults, without correlation with allelic and total level of expression.
British journal of cancer 1997;76(6):725-33.
1996: J Rachmilewitz; Michael Elkin; Leendert H J Looijenga; AJ Verkerk; Bernard Gonik; O Lustig; D Werner; Nathan de Groot; Abraham Hochberg
Characterization of the imprinted IPW gene: allelic expression in normal and tumorigenic human tissues.
Oncogene 1996;13(8):1687-92.
1996: M M Mostert; Martijn Van de Pol; D Olde Weghuis; Ron Suijkerbuijk; Ad Geurts van Kessel; Jannie van Echten; J Wolter Oosterhuis; Leendert H J Looijenga
Comparative genomic hybridization of germ cell tumors of the adult testis: confirmation of karyotypic findings and identification of a 12p-amplicon.
Cancer genetics and cytogenetics 1996;89(2):146-52.
1996: R A Olie; B Fenderson; K Daley; J Wolter Oosterhuis; J Murphy; Leendert H J Looijenga
Glycolipids of human primary testicular germ cell tumours.
British journal of cancer 1996;74(1):133-40.
1996: Peter W Andrews; J Casper; Ivan Damjanov; M Duggan-Keen; A Giwercman; J Hata; A von Keitz; Leendert H J Looijenga; José Luis Millán; J W Oosterhuis; M Pera; M Sawada; H J Schmoll; N E Skakkebaek; W van Putten; Peter L Stern
Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours.
International journal of cancer. Journal international du cancer 1996;66(6):806-16.
1996: R A Olie; Antonius W M Boersma; M C Dekker; Kees Nooter; Leendert H J Looijenga; J Wolter Oosterhuis
Apoptosis of human seminoma cells upon disruption of their microenvironment.
British journal of cancer 1996;73(9):1031-6.
1996: S Mosselman; Leendert H J Looijenga; Ad J M Gillis; Marga van Rooijen; H J Kraft; Everardus J J van Zoelen; J Wolter Oosterhuis
Aberrant platelet-derived growth factor alpha-receptor transcript as a diagnostic marker for early human germ cell tumors of the adult testis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2884-8.
1996: Jannie van Echten; J Wolter Oosterhuis; Leendert H J Looijenga; A Dam; Dirk T Sleijfer; HS Schraffordt Koops; Bauke de Jong
Mixed testicular germ cell tumors: monoclonal or polyclonal.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1996;9(4):371-4.
1996: M M Mostert; Martijn Van de Pol; Jannie van Echten; D Olde Weghuis; Ad Geurts van Kessel; J Wolter Oosterhuis; Leendert H J Looijenga
Fluorescence in situ hybridization-based approaches for detection of 12p overrepresentation, in particular i(12p), in cell lines of human testicular germ cell tumors of adults.
Cancer genetics and cytogenetics 1996;87(2):95-102.
1995: Jannie van Echten; Ruud van Gurp; M Stoepker; Leendert H J Looijenga; J de Jong; W Oosterhuis
Cytogenetic evidence that carcinoma in situ is the precursor lesion for invasive testicular germ cell tumors.
Cancer genetics and cytogenetics 1995;85(2):133-7.
1995: Jannie van Echten; J Wolter Oosterhuis; Leendert H J Looijenga; Martijn Van de Pol; J Wiersema; Gerard te Meerman; H Schaffordt Koops; Dirk T Sleijfer; Bauke de Jong
No recurrent structural abnormalities apart from i(12p) in primary germ cell tumors of the adult testis.
Genes, chromosomes & cancer 1995;14(2):133-44.
1995: R A Olie; Leendert H J Looijenga; Lucie Boerrigter; B Top; Sjoerd Rodenhuis; An Langeveld; M P Mulder; J Wolter Oosterhuis
N- and KRAS mutations in primary testicular germ cell tumors: incidence and possible biological implications.
Genes, chromosomes & cancer 1995;12(2):110-6.
1995: A C Lambrechts; Leendert H J Looijenga; Mars B van't Veer; Jannie van Echten; Wim Timens; J Wolter Oosterhuis
Lymphomas with testicular localisation show a consistent BCL-2 expression without a translocation (14;18): a molecular and immunohistochemical study.
British journal of cancer 1995;71(1):73-7.
1995: R A Olie; Leendert H J Looijenga; M C Dekker; Frank de Jong; F M van Dissel-Emiliani; D G de Rooij; B van der Holt; J Wolter Oosterhuis
Heterogeneity in the in vitro survival and proliferation of human seminoma cells.
British journal of cancer 1995;71(1):13-7.
1994: Ad J M Gillis; Leendert H J Looijenga; B de Jong; J Wolter Oosterhuis
Clonality of combined testicular germ cell tumors of adults.
Laboratory investigation; a journal of technical methods and pathology 1994;71(6):874-8.
1994: Leendert H J Looijenga; R A Olie; Ingrid van der Gaag; Frederik J van Sluijs; J Matoska; J Ploem-Zaaijer; C Knepflé; J Wolter Oosterhuis
Seminomas of the canine testis. Counterpart of spermatocytic seminoma of men?
Laboratory investigation; a journal of technical methods and pathology 1994;71(4):490-6.
1994: Ad J M Gillis; J Wolter Oosterhuis; M E Schipper; E J Barten; R van Berlo; Ruud van Gurp; M Abraham; G F Saunders; Leendert H J Looijenga
Origin and biology of a testicular Wilms' tumor.
Genes, chromosomes & cancer 1994;11(2):126-35.
1994: Ruud van Gurp; J Wolter Oosterhuis; Vera Kalscheuer; E C Mariman; Leendert H J Looijenga
Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors.
Journal of the National Cancer Institute 1994;86(14):1070-5.
1994: Leendert H J Looijenga; M Abraham; Ad J M Gillis; G F Saunders; J Wolter Oosterhuis
Testicular germ cell tumors of adults show deletions of chromosomal bands 11p13 and 11p15.5, but no abnormalities within the zinc-finger regions and exons 2 and 6 of the Wilms' tumor 1 gene.
Genes, chromosomes & cancer 1994;9(3):153-60.
1993: Leendert H J Looijenga; Ad J M Gillis; W L Van Putten; J Wolter Oosterhuis
In situ numeric analysis of centromeric regions of chromosomes 1, 12, and 15 of seminomas, nonseminomatous germ cell tumors, and carcinoma in situ of human testis.
Laboratory investigation; a journal of technical methods and pathology 1993;68(2):211-9.
1993: J W Oosterhuis; Leendert H J Looijenga; A Geurts van Kessel; B de Jong
A cytogenetic classification of germ cell tumors, and its biological relevance.
European urology 1993;23 Suppl 2():6-8.
1993: J Wolter Oosterhuis; Leendert H J Looijenga
The biology of human germ cell tumours: retrospective speculations and new prospectives.
European urology 1993;23(1):245-50.
1993: J Wolter Oosterhuis; Ad J M Gillis; W J van Putten; B de Jong; Leendert H J Looijenga
Interphase cytogenetics of carcinoma in situ of the testis. Numeric analysis of the chromosomes 1, 12 and 15.
European urology 1993;23(1):16-21; discussion 22.
1993: Ad Geurts van Kessel; Ron Suijkerbuijk; RJ Sinke; Leendert H J Looijenga; J Wolter Oosterhuis; Bauke de Jong
Molecular cytogenetics of human germ cell tumours: i(12p) and related chromosomal anomalies.
European urology 1993;23(1):23-8; discussion 29.
1992: Ron Suijkerbuijk; Leendert H J Looijenga; Bauke de Jong; J Wolter Oosterhuis; J J Cassiman; Ad Geurts van Kessel
Verification of isochromosome 12p and identification of other chromosome 12 aberrations in gonadal and extragonadal human germ cell tumors by bicolor double fluorescence in situ hybridization.
Cancer genetics and cytogenetics 1992;63(1):8-16.
1992: Leendert H J Looijenga; J Wolter Oosterhuis; Vincent T H B M Smit; J W Wessels; Paul Mollevanger; Peter Devilee
Alpha satellite DNAs on chromosomes 10 and 12 are both members of the dimeric suprachromosomal subfamily, but display little identity at the nucleotide sequence level.
Genomics 1992;13(4):1125-32.
1992: J W Oosterhuis; R S Menon; Leendert H J Looijenga
Pathology of soft tissue sarcomas. An introduction.
Journal belge de radiologie 1992;75(4):253-7.
1991: J C Berends; S E Schutte; F M van Dissel-Emiliani; D G de Rooij; Leendert H J Looijenga; J Wolter Oosterhuis
Significant improvement of the survival of seminoma cells in vitro by use of a rat Sertoli cell feeder layer and serum-free medium.
Journal of the National Cancer Institute 1991;83(19):1400-3.
1991: Leendert H J Looijenga; J Wolter Oosterhuis; F C Ramaekers; Bauke de Jong; A Dam; J L Beck; Dirk T Sleijfer; HS Schraffordt Koops
Dual parameter flow cytometry for deoxyribonucleic acid and intermediate filament proteins of residual mature teratoma. All tumor cells are aneuploid.
Laboratory investigation; a journal of technical methods and pathology 1991;64(1):113-7.
1990: Leendert H J Looijenga; Vincent T H B M Smit; J W Wessels; Paul Mollevanger; J Wolter Oosterhuis; Cees J Cornelisse; Peter Devilee
Localization and polymorphism of a chromosome 12-specific alpha satellite DNA sequence.
Cytogenetics and cell genetics 1990;53(4):216-8.