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Markus Metzler

Research Profile

Chemicals & Drugs

Disorders

Living Beings

Infants

Concepts & Ideas

Molecular Sequence Data

Procedures

Anatomy

Physiology

Gene Rearrangement, T-Lymphocyte

Genes & Molecular Sequences

Proto-Oncogenes

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Publications

TOP 3
Lilian Kuster; Reinhard Grausenburger; Gerhard Fuka; Ulrike Kaindl; Gerd Krapf; Andrea Inthal; Georg Mann; Maximilian Kauer; Johannes Rainer; Reinhard Kofler; Andrew Hall; Markus Metzler; Lüder Hinrich Meyer; Claus Meyer; Jochen Harbott; Rolf Marschalek; Sabine Strehl; Oskar A Haas; Renate Panzer-Grümayer
ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
H von Goessel; U Jacobs; S Semper; M Krumbholz; Thorsten Langer; T Keller; A Schrauder; V H J van der Velden; J J M van Dongen; Jochen Harbott; E R Panzer-Grümayer; M Schrappe; Wolfgang Rascher; Markus Metzler
Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.
Ruxandra Farcas; Eberhard Schneider; Katrin Frauenknecht; Ivanela Kondova; Ronald Bontrop; Jürgen Bohl; Bianca Navarro; Markus Metzler; Hans Zischler; Ulrich Zechner; Angelika Daser; Thomas Haaf
Differences in DNA methylation patterns and expression of the CCRK gene in human and nonhuman primate cortices.

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All Publications

2011: Lilian Kuster; Reinhard Grausenburger; Gerhard Fuka; Ulrike Kaindl; Gerd Krapf; Andrea Inthal; Georg Mann; Maximilian Kauer; Johannes Rainer; Reinhard Kofler; Andrew Hall; Markus Metzler; Lüder Hinrich Meyer; Claus Meyer; Jochen Harbott; Rolf Marschalek; Sabine Strehl; Oskar A Haas; Renate Panzer-Grümayer
ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
Blood 2011;117(9):2658-67.
2009: H von Goessel; U Jacobs; S Semper; M Krumbholz; Thorsten Langer; T Keller; A Schrauder; V H J van der Velden; J J M van Dongen; Jochen Harbott; E R Panzer-Grümayer; M Schrappe; Wolfgang Rascher; Markus Metzler
Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.
Leukemia research 2009;33(8):1082-8.
2009: Ruxandra Farcas; Eberhard Schneider; Katrin Frauenknecht; Ivanela Kondova; Ronald Bontrop; Jürgen Bohl; Bianca Navarro; Markus Metzler; Hans Zischler; Ulrich Zechner; Angelika Daser; Thomas Haaf
Differences in DNA methylation patterns and expression of the CCRK gene in human and nonhuman primate cortices.
Molecular biology and evolution 2009;26(6):1379-89.
2008: M Natividad Lobato; Markus Metzler; Lesley Drynan; Alan Forster; Richard Pannell; Terence H Rabbitts
Modeling chromosomal translocations using conditional alleles to recapitulate initiating events in human leukemias.
Journal of the National Cancer Institute. Monographs 2008;(39):58-63.
2007: Susanna Fischer; Georg Mann; Marianne Konrad; Markus Metzler; Georg Ebetsberger; Neil Jones; Bertrand Nadel; Olaf Bodamer; Oskar A Haas; Klaus Schmitt; E Renate Panzer-Grümayer
Screening for leukemia- and clone-specific markers at birth in children with T-cell precursor ALL suggests a predominantly postnatal origin.
Blood 2007;110(8):3036-8.
2007: Markus Metzler; Jochen Bruch; Daniel Stachel; Thorsten Langer; Arndt Borkhardt; Jochen Harbott; Wolfgang Rascher; Wolfgang Holter
Temporary blast reduction after immunoglobulin administration for congenital cytomegalovirus infection masking infant leukemia with cryptic MLL rearrangement.
Leukemia research 2007;31(4):553-7.
2006: E Struwe; K Krammer; Jörg Dötsch; Markus Metzler; Helmuth G Dörr; Robert Cesnjevar; Wolfgang Rascher; Andreas Koch
No evidence for angiotensin type 2 receptor gene polymorphism in intron 1 in patients with coarctation of the aorta and Ullrich-Turner syndrome.
Pediatric cardiology 2006;27(5):636-9.
2006: Markus Metzler; Alan Forster; Richard Pannell; M J Arends; Angelika Daser; M Natividad Lobato; Terence H Rabbitts
A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology.
Oncogene 2006;25(22):3093-103.
2006: Markus Metzler; Georg Mann; Uli Monschein; Martin Lodzinski; Christine Gall; Thomas Flohr; Susanne Viehmann; Thorsten Langer; Martin Schrappe; Helmut Gadner; Oskar A Haas; E Renate Panzer-Grümayer
Minimal residual disease analysis in children with t(12;21)-positive acute lymphoblastic leukemia: comparison of Ig/TCR rearrangements and the genomic fusion gene.
Haematologica 2006;91(5):683-6.
2006: Markus Metzler; Dieter K Luedecke; Wolfgang Saeger; Annette Grueters; Hannes Haberl; Wieland Kiess; Roland Repp; Wolfgang Rascher; Joerg Doetsch
Low prevalence of Gs alpha mutations in śomatotroph adenomas of children and adolescents.
Cancer genetics and cytogenetics 2006;166(2):146-51.
2005: Rosalind Codrington; Richard Pannell; Alan Forster; Lesley F Drynan; Angelika Daser; Nati Lobato; Markus Metzler; Terence H Rabbitts
The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells.
PLoS biology 2005;3(8):e242.
2005: Monika Wilda; Antje Vega Perez; Jochen Bruch; Willi Woessmann; Markus Metzler; Uta Fuchs; Arndt Borkhardt
Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5).
Genes, chromosomes & cancer 2005;43(4):424-6.
2005: Alan Forster; Richard Pannell; Lesley F Drynan; F Cano; N Chan; Rosalind Codrington; Angelika Daser; N Lobato; Markus Metzler; C-H Nam; S Rodriguez; Tomoyuki Tanaka; Terence H Rabbitts
Chromosomal translocation engineering to recapitulate primary events of human cancer.
Cold Spring Harbor symposia on quantitative biology 2005;70():275-82.
2005: Alan Forster; Richard Pannell; Lesley F Drynan; Rosalind Codrington; Angelika Daser; Markus Metzler; M Natividad Lobato; Terence H Rabbitts
The invertor knock-in conditional chromosomal translocation mimic.
Nature methods 2005;2(1):27-30.
2004: Thorben Kracht; Martin Schrappe; Sabine Strehl; Alfred Reiter; Holger-Andreas Elsner; Jan Trka; Gunnar Cario; Susanne Viehmann; Jochen Harbott; Arndt Borkhardt; Markus Metzler; Thorsten Langer; Roland Repp; Rolf Marschalek; Karl Welte; Oskar A Haas; Martin Stanulla
NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.
Haematologica 2004;89(12):1492-7.
2004: Markus Metzler; Pamela L Strissel; Reiner Strick; Charlotte Niemeyer; Silja Roettgers; Arndt Borkhardt; Jochen Harbott; Wolf D Ludwig; Martin Stanulla; Martin Schrappe; Dirk Reinhardt; Ursula Creutzig; Jörn D Beck; Wolfgang Rascher; Roland Repp; Thorsten Langer
Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2004;41(3):291-6.
2004: Ana Teresa Maia; Joachim Koechling; Robin Corbett; Markus Metzler; Joseph L Wiemels; Mel Greaves
Protracted postnatal natural histories in childhood leukemia.
Genes, chromosomes & cancer 2004;39(4):335-40.
2004: Markus Metzler; Monika Wilda; Kerstin Busch; Susanne Viehmann; Arndt Borkhardt
High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma.
Genes, chromosomes & cancer 2004;39(2):167-9.
2004: Markus Metzler; U Brehm; Thorsten Langer; Susanne Viehmann; Arndt Borkhardt; Martin Stanulla; Martin Schrappe; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Asymmetric multiplex-polymerase chain reaction - a high throughput method for detection and sequencing genomic fusion sites in t(4;11).
British journal of haematology 2004;124(1):47-54.
2003: Ina Knerr; Markus Metzler; Charlotte M Niemeyer; Wolfgang Holter; Anja Gerecke; Irith Baumann; Regina Trollmann; Roland Repp
Hematologic features and clinical course of an infant with Pearson syndrome caused by a novel deletion of mitochondrial DNA.
Journal of pediatric hematology/oncology 2003;25(12):948-51.
2003: Jochen Bruch; Monika Wilda; Andrea Teigler-Schlegel; Jochen Harbott; Arndt Borkhardt; Markus Metzler
Occurrence of an MLL/LAF4 fusion gene caused by the insertion ins(11;2)(q23;q11.2q11.2) in an infant with acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2003;37(1):106-9.
2003: Marianne Konrad; Markus Metzler; Simon Panzer; Iris Ostreicher; Martina Peham; Reinald Repp; Oskar A Haas; Helmut Gadner; E Renate Panzer-Grumayer
Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone.
Blood 2003;101(9):3635-40.
2003: Thorsten Langer; Markus Metzler; Dirk Reinhardt; Susanne Viehmann; Arndt Borkhardt; Martin Reichel; Martin Stanulla; Martin Schrappe; Ursula Creutzig; Jörg Ritter; Thomas Leis; Ulla Jacobs; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Genes, chromosomes & cancer 2003;36(4):393-401.
2003: Matthias T F Wolf; Jörg Dötsch; Markus Metzler; M Holder; R Repp; Wolfgang Rascher
A new missense mutation of the vasopressin-neurophysin II gene in a family with neurohypophyseal diabetes insipidus.
Hormone research 2003;60(3):143-7.
2002: Johannes-Peter Haas; Markus Metzler; Hans Ruder; Rüdiger Waldherr; Michael Böswald; Thomas Rupprecht
An unusual manifestation of Wegener's granulomatosis in a 4-year-old girl.
Pediatric neurology 2002;27(1):71-4.
2002: Ina Knerr; Cornelia Dachert; Ernst Beinder; Markus Metzler; Jörg Dötsch; Roland Repp; Wolfgang Rascher
Adrenomedullin, calcitonin gene-related peptide and their receptors: evidence for a decreased placental mRNA content in preeclampsia and HELLP syndrome.
European journal of obstetrics, gynecology, and reproductive biology 2002;101(1):47-53.
2001: Michael Gröschl; Manfred Rauh; R Wagner; Winfried Neuhuber; Markus Metzler; Gültekin Tamgüney; Johannes Zenk; Ellen Schoof; Helmuth G Dörr; Werner Blum; Wolfgang Rascher; Jörg Dötsch
Identification of leptin in human saliva.
The Journal of clinical endocrinology and metabolism 2001;86(11):5234-9.
2000: F Schläger; Stephan Schaefer; Markus Metzler; N Gratzki; Fritz H Lampert; Wolfram H Gerlich; Roland Repp
Quantitative DNA fragment analysis for detecting low amounts of hepatitis B virus deletion mutants in highly viremic carriers.
Hepatology (Baltimore, Md.) 2000;32(5):1096-105.
2000: C Welz; Winfried Neuhuber; H Schreier; Markus Metzler; R Repp; W Rascher; Alfred Fahr
Nuclear transport of oligonucleotides in HepG2-cells mediated by protamine sulfate and negatively charged liposomes.
Pharmaceutical research 2000;17(10):1206-11.
1998: Thomas Leis; Roland Repp; Arndt Borkhardt; Markus Metzler; F Schläger; Jochen Harbott; Fritz H Lampert
A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level.
Leukemia 1998;12(5):758-63.