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mark gorrell

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mark gorrell; Geoffrey W McCaughan; Amany Zekry; Andrew Lloyd
The long and the short of interferon-gamma-inducible protein 10 in hepatitis C virus infection.
Lisa Lo; Geoffrey W McCaughan; Susan V McLennan; James Bonner; Sumaiya Chowdhury; mark gorrell; Paul F Williams; Dennis K Yue; Stephen M Twigg
Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis.
Tsun-Wen Yao; Denise M T Yu; Kang-Yell Choi; Woo-Shin Kim; Geoffrey W McCaughan; George Sharbeen; Pu Xia; mark gorrell
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling.

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2011: mark gorrell; Geoffrey W McCaughan; Amany Zekry; Andrew Lloyd
The long and the short of interferon-gamma-inducible protein 10 in hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2011;54(5):1875-9.
2011: Lisa Lo; Geoffrey W McCaughan; Susan V McLennan; James Bonner; Sumaiya Chowdhury; mark gorrell; Paul F Williams; Dennis K Yue; Stephen M Twigg
Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis.
Journal of hepatology 2011;55(2):435-44.
2011: Tsun-Wen Yao; Denise M T Yu; Kang-Yell Choi; Woo-Shin Kim; Geoffrey W McCaughan; George Sharbeen; Pu Xia; mark gorrell
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling.
Molecular cancer research : MCR 2011;9(7):948-59.
2011: Fiona M Keane; Naveed A Nadvi; Tsun-Wen Yao; mark gorrell
Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α.
The FEBS journal 2011;278(8):1316-32.
2011: J H Martin; C F Deacon; mark gorrell; J B Prins
Incretin-based therapies--review of the physiology, pharmacology and emerging clinical experience.
Internal medicine journal 2011;41(4):299-307.
2011: Sunmi Song; Nicholas A Shackel; Xin M Wang; Katerina Ajami; Geoffrey W McCaughan; mark gorrell
Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver.
The American journal of pathology 2011;178(3):1134-44.
2011: Denise M T Yu; L Slaitini; V Gysbers; A G M Riekhoff; Thilo Kähne; H M Knott; I De Meester; Catherine A Abbott; Geoffrey W McCaughan; mark gorrell
Soluble CD26 / dipeptidyl peptidase IV enhances human lymphocyte proliferation in vitro independent of dipeptidyl peptidase enzyme activity and adenosine deaminase binding.
Scandinavian journal of immunology 2011;73(2):102-11.
2010: Detlef Schuppan; mark gorrell; Thomas Klein; Michael Mark; Nezam H Afdhal
The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(6):795-808.
2010: Denise M T Yu; Tsun-Wen Yao; Sumaiya Chowdhury; Naveed A Nadvi; Brenna Osborne; W Bret Church; Geoffrey W McCaughan; mark gorrell
The dipeptidyl peptidase IV family in cancer and cell biology.
The FEBS journal 2010;277(5):1126-44.
2010: Mark Kirby; Denise M T Yu; Steven O'Connor; mark gorrell
Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition.
Clinical science (London, England : 1979) 2010;118(1):31-41.
2009: Alexandra Sharland; mark gorrell
Cooperation of innate and adaptive immunity in the pathogenesis of biliary atresia: there's a killer on the run.
Hepatology (Baltimore, Md.) 2009;50(6):2037-40.
2009: Denise M T Yu; Katerina Ajami; Margaret G Gall; Joohong Park; C Soon Lee; Kathryn A Evans; Eileen McLaughlin; Melissa R Pitman; Catherine A Abbott; Geoffrey W McCaughan; mark gorrell
The in vivo expression of dipeptidyl peptidases 8 and 9.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(11):1025-40.
2009: Jim Manos; Jonathan Arthur; Barbara Rose; Scott Bell; Pholawat Tingpej; Honghua Hu; Jeremy Webb; Staffan Kjelleberg; mark gorrell; Peter Bye; Colin Harbour
Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth.
FEMS microbiology letters 2009;292(1):107-14.
2008: Jim Manos; Jonathan Arthur; Barbara Rose; Pholawat Tingpej; Carina Fung; Michelle Curtis; Jeremy S Webb; Honghua Hu; Staffan Kjelleberg; mark gorrell; Peter T P Bye; Colin Harbour
Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung.
Journal of medical microbiology 2008;57(Pt 12):1454-65.
2008: Peter D Tran; Dale Christiansen; Adam Winterhalter; Andrew Brooks; mark gorrell; Benjamin G Lilienfeld; Jörg D Seebach; Mauro Sandrin; Alexandra Sharland
Porcine cells express more than one functional ligand for the human lymphocyte activating receptor NKG2D.
Xenotransplantation 2008;15(5):321-32.
2008: Manuela G Neuman; Kevin Sha; Rustan Esguerra; Sam Zakhari; Robert E Winkler; Nir Hilzenrat; Jonathan Wyse; Curtis L Cooper; Devanshi Seth; mark gorrell; Paul S Haber; Geoffrey W McCaughan; Maria A Leo; Charles S Lieber; Mihai Voiculescu; Eugenia Buzatu; Camelia Ionescu; Jozsef Dudas; Bernhard Saile; Giuliano Ramadori
Inflammation and repair in viral hepatitis C.
Digestive diseases and sciences 2008;53(6):1468-87.
2008: Devanshi Seth; Philip J Hogg; mark gorrell; Geoffrey W McCaughan; Paul S Haber
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease.
Journal of hepatology 2008;48(4):614-27.
2008: Katerina Ajami; Melissa R Pitman; Claire H Wilson; Joohong Park; R Ian Menz; Amanda E Starr; Jennifer H Cox; Catherine A Abbott; Christopher M Overall; mark gorrell
Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8.
FEBS letters 2008;582(5):819-25.
2008: mark gorrell
Impaired glucose tolerance and incretins in chronic liver disease.
Journal of gastroenterology and hepatology 2008;23(2):166-7.
2008: Xin Maggie Wang; Tsun-Wen Yao; Naveed A Nadvi; Brenna Osborne; Geoffrey W McCaughan; mark gorrell
Fibroblast activation protein and chronic liver disease.
Frontiers in bioscience : a journal and virtual library 2008;13():3168-80.
2007: mark gorrell
Liver fibrosis: the hepatocyte revisited.
Hepatology (Baltimore, Md.) 2007;46(5):1659-61.
2007: Xiao X Huang; Geoffrey W McCaughan; Nicholas A Shackel; mark gorrell
Up-regulation of proproliferative genes and the ligand/receptor pair placental growth factor and vascular endothelial growth factor receptor 1 in hepatitis C cirrhosis.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):960-8.
2007: mark gorrell; Fiona J Warner
Fooling the liver: malaria incognito.
Hepatology (Baltimore, Md.) 2007;45(3):826.
2006: Devanshi Seth; mark gorrell; Shaun Cordoba; Geoffrey W McCaughan; Paul S Haber
Intrahepatic gene expression in human alcoholic hepatitis.
Journal of hepatology 2006;45(2):306-20.
2006: Denise M T Yu; Xin M Wang; Geoffrey W McCaughan; mark gorrell
Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.
The FEBS journal 2006;273(11):2447-60.
2006: Nicholas A Shackel; Devanshi Seth; Paul S Haber; mark gorrell; Geoffrey W McCaughan
The hepatic transcriptome in human liver disease.
Comparative hepatology 2006;5():6.
2006: Xin M Wang; Denise M T Yu; Geoffrey W McCaughan; mark gorrell
Extra-enzymatic roles of DPIV and FAP in cell adhesion and migration on collagen and fibronectin.
Advances in experimental medicine and biology 2006;575():213-22.
2006: Joohong Park; Katerina Ajami; Denise M T Yu; mark gorrell
Dipeptidyl peptidase 8 has post-proline dipeptidyl aminopeptidase and prolyl endopeptidase activities.
Advances in experimental medicine and biology 2006;575():93-102.
2006: Denise M T Yu; Xin M Wang; Katerina Ajami; Geoffrey W McCaughan; mark gorrell
DP8 and DP9 have extra-enzymatic roles in cell adhesion, migration and apoptosis.
Advances in experimental medicine and biology 2006;575():63-72.
2006: mark gorrell; Xin M Wang; Joohong Park; Katerina Ajami; Denise M T Yu; Heather Knott; Devanshi Seth; Geoffrey W McCaughan
Structure and function in dipeptidyl peptidase IV and related proteins.
Advances in experimental medicine and biology 2006;575():45-54.
2006: Tong Chen; Katerina Ajami; Geoffrey W McCaughan; Wei Ping Gai; mark gorrell; Catherine A Abbott
Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity.
Biochimica et biophysica acta 2006;1764(1):33-43.
2005: Xin Maggie Wang; Denise M T Yu; Geoffrey W McCaughan; mark gorrell
Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line.
Hepatology (Baltimore, Md.) 2005;42(4):935-45.
2005: mark gorrell
Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders.
Clinical science (London, England : 1979) 2005;108(4):277-92.
2004: Katerina Ajami; Catherine A Abbott; Geoffrey W McCaughan; mark gorrell
Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity.
Biochimica et biophysica acta 2004;1679(1):18-28.
2003: Paul S Haber; Ross Warner; Devanshi Seth; mark gorrell; Geoffrey W McCaughan
Pathogenesis and management of alcoholic hepatitis.
Journal of gastroenterology and hepatology 2003;18(12):1332-44.
2003: Devanshi Seth; Maria A Leo; Peter H McGuinness; Charles S Lieber; Yvonne Brennan; Rohan Williams; Xin M Wang; Geoffrey W McCaughan; mark gorrell; Paul S Haber
Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liver.
The American journal of pathology 2003;163(6):2303-17.
2003: Nicholas A Shackel; Peter H McGuinness; Catherine A Abbott; mark gorrell; Geoffrey W McCaughan
Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization.
Hepatology (Baltimore, Md.) 2003;38(3):577-88.
2003: Susan Lorey; Angela Stöckel-Maschek; Jürgen Faust; Wolfgang Brandt; Beate Stiebitz; mark gorrell; Thilo Kähne; Carmen Mrestani-Klaus; Sabine Wrenger; Dirk Reinhold; Siegfried Ansorge; Klaus Neubert
Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites.
European journal of biochemistry / FEBS 2003;270(10):2147-56.
2003: Devanshi Seth; mark gorrell; Peter H McGuinness; Maria A Leo; Charles S Lieber; Geoffrey W McCaughan; Paul S Haber
SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primates.
Journal of biochemical and biophysical methods 2003;55(1):53-66.
2003: Katerina Ajami; Catherine A Abbott; Mina Obradovic; Vanessa Gysbers; Thilo Kähne; Geoffrey W McCaughan; mark gorrell
Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family.
Biochemistry 2003;42(3):694-701.
2003: mark gorrell; Xin M Wang; Miriam T Levy; Eleanor P W Kable; George Marinos; Guy Cox; Geoffrey W McCaughan
Intrahepatic expression of collagen and fibroblast activation protein (FAP) in hepatitis C virus infection.
Advances in experimental medicine and biology 2003;524():235-43.
2003: Tong Chen; Katerina Ajami; Geoffrey W McCaughan; mark gorrell; Catherine A Abbott
Dipeptidyl peptidase IV gene family. The DPIV family.
Advances in experimental medicine and biology 2003;524():79-86.
2003: Angela Stöckel-Maschek; Beate Stiebitz; Jürgen Faust; Ilona Born; Thilo Kähne; mark gorrell; Klaus Neubert
Different inhibition mechanisms of dipeptidyl peptidase IV by tryptophan containing peptides and amides.
Advances in experimental medicine and biology 2003;524():69-72.
2003: Katerina Ajami; Catherine A Abbott; Vanessa Gysbers; Thilo Kähne; Geoffrey W McCaughan; mark gorrell
Molecular chimeras and mutational analysis in the prolyl oligopeptidase gene family.
Advances in experimental medicine and biology 2003;524():49-55.
2003: Guy Cox; Eleanor P W Kable; Allan Jones; Ian Fraser; Frank Manconi; mark gorrell
3-dimensional imaging of collagen using second harmonic generation.
Journal of structural biology 2003;141(1):53-62.
2003: mark gorrell
First bite.
Nature structural biology 2003;10(1):3-5.
2002: Nicholas A Shackel; mark gorrell; Geoffrey W McCaughan
Gene array analysis and the liver.
Hepatology (Baltimore, Md.) 2002;36(6):1313-25.
2002: Miriam T Levy; Geoffrey W McCaughan; G Marinos; mark gorrell
Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection.
Liver 2002;22(2):93-101.
2002: Nicholas A Shackel; Peter H McGuinness; Catherine A Abbott; mark gorrell; Geoffrey W McCaughan
Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression.
The American journal of pathology 2002;160(2):641-54.
2002: Min Wang; mark gorrell; Catherine A Abbott; Rene Jaggi; Didier Marguet; Ronald G Dickinson
Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.
Journal of gastroenterology and hepatology 2002;17(1):66-71.
2001: G W McGaughan; Nicholas A Shackel; mark gorrell
Discussion on differential gene expression between chronic hepatitis B and C hepatic lesion.
Gastroenterology 2001;121(5):1263-4.
2001: Nicholas A Shackel; Peter H McGuinness; Catherine A Abbott; mark gorrell; Geoffrey W McCaughan
Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression.
Gut 2001;49(4):565-76.
2001: mark gorrell; Vanessa Gysbers; Geoffrey W McCaughan
CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.
Scandinavian journal of immunology 2001;54(3):249-64.
2001: Min Wang; mark gorrell; G W McGaughan; Ronald G Dickinson
Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.
Life sciences 2001;68(7):785-97.
2000: Catherine A Abbott; Denise M T Yu; E Woollatt; G R Sutherland; Geoffrey W McCaughan; mark gorrell
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.
European journal of biochemistry / FEBS 2000;267(20):6140-50.
2000: Geoffrey W McCaughan; mark gorrell; G Alex Bishop; Catherine A Abbott; Nicholas A Shackel; Peter H McGuinness; Miriam T Levy; Alexandra F Sharland; David G Bowen; D Yu; L Slaitini; WB Church; J Napoli
Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance.
Immunological reviews 2000;174():172-91.
2000: Catherine A Abbott; D Yu; Geoffrey W McCaughan; mark gorrell
Post-proline-cleaving peptidases having DP IV like enzyme activity. Post-proline peptidases.
Advances in experimental medicine and biology 2000;477():103-9.
2000: mark gorrell; Catherine A Abbott; Thilo Kähne; Miriam T Levy; WB Church; Geoffrey W McCaughan
Relating structure to function in the beta-propeller domain of dipeptidyl peptidase IV. Point mutations that influence adenosine deaminase binding, antibody binding and enzyme activity.
Advances in experimental medicine and biology 2000;477():89-95.
1999: Catherine A Abbott; Geoffrey W McCaughan; Miriam T Levy; WB Church; mark gorrell
Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted beta propeller domain.
European journal of biochemistry / FEBS 1999;266(3):798-810.
1999: Catherine A Abbott; Geoffrey W McCaughan; mark gorrell
Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity.
FEBS letters 1999;458(3):278-84.
1999: Miriam T Levy; Geoffrey W McCaughan; Catherine A Abbott; J E Park; A M Cunningham; E Müller; W J Rettig; mark gorrell
Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis.
Hepatology (Baltimore, Md.) 1999;29(6):1768-78.
1997: T Oravecz; M Pall; Gregory Roderiquez; mark gorrell; M Ditto; N Y Nguyen; Robert A Boykins; Edward Joseph Unsworth; Michael A Norcross
Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage.
The Journal of experimental medicine 1997;186(11):1865-72.
1997: mark gorrell; J A Lemm; C M Rice; Diane E Griffin
Immunization with nonstructural proteins promotes functional recovery of alphavirus-infected neurons.
Journal of virology 1997;71(5):3415-9.
1997: W L Townsend; mark gorrell; R Mayer
Langerhans cells in the development of skin cancer: a qualitative and quantitative comparison of cell markers in normal, acanthotic and neoplastic ovine skin.
Pathology 1997;29(1):42-50.
1997: Catherine A Abbott; mark gorrell; Miriam T Levy; Geoffrey W McCaughan
Molecular analyses of human and rat dipeptidyl peptidase IV.
Advances in experimental medicine and biology 1997;421():161-9.
1995: W L Townsend; mark gorrell; PW Ladds
Major histocompatibility complex antigens in normal, acanthotic and neoplastic ovine skin: an association been tumor invasiveness and low level MHC class I expression.
Veterinary immunology and immunopathology 1995;45(3-4):237-52.
1995: mark gorrell; W L Townsend; PW Ladds
The distribution of lymphocyte subpopulations in normal and acanthotic ovine skin.
Veterinary immunology and immunopathology 1995;44(2):151-67.
1992: M F McEntee; mark gorrell; Robert J Adams; Opendra Narayan; PAULA PITHA-ROWE
Tumour necrosis factor and interleukin 6 production during interaction between activated CD4+ lymphocytes and simian immunodeficiency virus-infected macrophages.
The Journal of general virology 1992;73 ( Pt 5)():1107-13.
1992: mark gorrell; M R Brandon; D Sheffer; Robert J Adams; Opendra Narayan
Ovine lentivirus is macrophagetropic and does not replicate productively in T lymphocytes.
Journal of virology 1992;66(5):2679-88.
1992: Opendra Narayan; MARY ZINK; mark gorrell; M McEntee; D Sharma; Robert J Adams
Lentivirus induced arthritis in animals.
The Journal of rheumatology. Supplement 1992;32():25-32; discussion 32-4.
1991: V Saravanamuthu; R A Foster; PW Ladds; mark gorrell
T and B lymphocyte subsets in spermatic granulomas in five rams.
Veterinary pathology 1991;28(6):482-91.
1991: mark gorrell; J Wickson; Geoffrey W McCaughan
Expression of the rat CD26 antigen (dipeptidyl peptidase IV) on subpopulations of rat lymphocytes.
Cellular immunology 1991;134(1):205-15.
1990: Geoffrey W McCaughan; J Wickson; mark gorrell
Characterization of the rat CD26 antigen.
Transplantation proceedings 1990;22(5):2103-4.
1990: Els N T Meeusen; G J Barcham; mark gorrell; M D Rickard; MR Brandon
Cysticercosis: cellular immune responses during primary and secondary infection.
Parasite immunology 1990;12(4):403-18.
1990: Geoffrey W McCaughan; J E Wickson; P F Creswick; mark gorrell
Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence.
Hepatology (Baltimore, Md.) 1990;11(4):534-44.
1989: C Burrells; Peter F Nettleton; Hugh W Reid; Hugh Miller; J Hopkins; I McConnell; mark gorrell; M R Brandon
Lymphocyte subpopulations in the blood of sheep persistently infected with border disease virus.
Clinical and experimental immunology 1989;76(3):446-51.
1989: Els N T Meeusen; mark gorrell; M D Rickard; MR Brandon
Lymphocyte subpopulations of sheep in protective immunity to Taenia hydatigena.
Parasite immunology 1989;11(2):169-81.
1988: mark gorrell; Hugh Miller; MR Brandon
Lymphocyte phenotypes in the abomasal mucosa of sheep infected with Haemonchus contortus.
Parasite immunology 1988;10(6):661-74.
1988: Els N T Meeusen; mark gorrell; MR Brandon
Presence of a distinct CD8+ and CD5- leucocyte subpopulation in the sheep liver.
Immunology 1988;64(4):615-9.
1988: mark gorrell; G Willis; MR Brandon; A K Lascelles
Lymphocyte phenotypes in the intestinal mucosa of sheep infected with Trichostrongylus colubriformis.
Clinical and experimental immunology 1988;72(2):274-9.
1987: N K Puri; mark gorrell; MR Brandon
Sheep MHC class II molecules. I. Immunochemical characterization.
Immunology 1987;62(4):567-73.
1987: D L Emery; N K Puri; J H Dufty; mark gorrell; MR Brandon
A functional and biochemical analysis of bovine class II MHC antigens using monoclonal antibodies.
Veterinary immunology and immunopathology 1987;16(3-4):215-34.
1984: mark gorrell; G L Milliken; B J Anderson; A Pucci
An enzyme immunoassay for bovine brucellosis using a monoclonal antibody specific for field strains of Brucella abortus.
Developments in biological standardization 1984;56():491-4.