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TOREN FINKEL

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Wen-Mei Yu; Jinhua Shen; Hal E Broxmeyer; TOREN FINKEL; Stanton L Gerson; Olga Jovanovic; Xia Liu; Elena E Pohl; Cheng-Kui Qu
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Nisha Narayan; Ilsa I Rovira; Michael N Sack; Junhui Sun; Guang Tong; Guanghui Wang; Renee Wong; Fredrick W Alt; Ronen Borenstein; Liu Cao; Hwei-Ling Cheng; Maria M Fergusson; Marjan Gucek; In Hye Lee; Jie Liu; David Lombard; Elizabeth Murphy; TOREN FINKEL
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Michael N Sack; TOREN FINKEL
Mitochondrial metabolism, sirtuins, and aging.

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2013: Wen-Mei Yu; Jinhua Shen; Hal E Broxmeyer; TOREN FINKEL; Stanton L Gerson; Olga Jovanovic; Xia Liu; Elena E Pohl; Cheng-Kui Qu
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Cell stem cell 2013;12(1):62-74.
2012: Nisha Narayan; Ilsa I Rovira; Michael N Sack; Junhui Sun; Guang Tong; Guanghui Wang; Renee Wong; Fredrick W Alt; Ronen Borenstein; Liu Cao; Hwei-Ling Cheng; Maria M Fergusson; Marjan Gucek; In Hye Lee; Jie Liu; David Lombard; Elizabeth Murphy; TOREN FINKEL
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Nature 2012;492(7428):199-204.
2012: Michael N Sack; TOREN FINKEL
Mitochondrial metabolism, sirtuins, and aging.
Cold Spring Harbor perspectives in biology 2012;4(12):.
2012: TOREN FINKEL
Relief with rapamycin: mTOR inhibition protects against radiation-induced mucositis.
Cell stem cell 2012;11(3):287-8.
2012: In Hye Lee; Noboru Motoyama; Ilsa I Rovira; Yoshichika Kawai; Alexander bishop; Liu Cao; Maria M Fergusson; TOREN FINKEL
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.
Science (New York, N.Y.) 2012;336(6078):225-8.
2012: Daniel J Klionsky; Jochen Klucken; Erwin Knecht; Ben C B Ko; Jan C Koch; Hiroshi Koga; Jae-Young Koh; Young Ho Koh; Masato Koike; Masaaki Komatsu; Eiki Kominami; Hee Jeong Kong; Wei-Jia Kong; Viktor I Korolchuk; Yaichiro Kotake; Michael I Koukourakis; Juan B Kouri Flores; Attila L Kovács; Claudine Kraft; Dimitri Krainc; Helmut Krämer; Carole Kretz-Remy; Anna M Krichevsky; Guido Kroemer; Rejko Krüger; Oleg Krut; Nicholas T Ktistakis; Chia-Yi Kuan; Roza Kucharczyk; Ashok Kumar; Raj Kumar; Sharad Kumar; Mondira Kundu; Hsing-Jien Kung; Tino Kurz; Ho Jeong Kwon; Albert R La Spada; Frank Lafont; Trond Lamark; Jacques Landry; Jon D Lane; Pierre Lapaquette; Jocelyn F Laporte; Lajos László; Sergio Lavandero; Josée N Lavoie; Robert Layfield; Pedro A Lazo; Laurent Le Cam; Weidong Le; Daniel J Ledbetter; Alvin J X Lee; Byung-Wan Lee; Gyun Min Lee; Jongdae Lee; Ju-Hyun Lee; Michael Lee; Myung-Shik Lee; Sug Hyung Lee; Christiaan Leeuwenburgh; Patrick Legembre; Renaud Legouis; Michael Lehmann; Huan-Yao Lei; Qun-Ying Lei; David A Leib; José Leiro; John J Lemasters; Antoinette Lemoine; Maciej S Lesniak; Dina Lev; Victor V Levenson; Beth Levine; Efrat Levy; Faqiang Li; Jun-Lin Li; Lian Li; Sheng Li; Weijie Li; Xue-Jun Li; Yan-bo Li; Yi-Ping Li; Chengyu Liang; Qiangrong Liang; Yung-Feng Liao; Pawel P Liberski; Andrew P Lieberman; Hyunjung J Lim; Kyu Lim; Kah-Leong Lim; Chiou-Feng Lin; Fu-Cheng Lin; Jian Lin; Jiandie D Lin; Kui Lin; Weei-Chin Lin; Wan-Wan Lin; Yi-Ling Lin; Rafael Linden; Paul Lingor; Jennifer Lippincott-Schwartz; Michael P Lisanti; Paloma B Liton; Bo Liu; Chun-Feng Liu; Kaiyu Liu; Leyuan Liu; Qiong A Liu; Wei Liu; Yule Liu; Young-Chau Liu; Richard A Lockshin; Chun-Nam Lok; Sagar Lonial; Benjamin Loos; Gabriel Lopez-Berestein; Carlos López-Otín; Laura Lossi; Michael T Lotze; Peter Lőw; Binfeng Lu; Bingwei Lu; Bo Lu; Zhen Lu; Frédéric Luciano; Nicholas W Lukacs; Anders H Lund; Melinda A Lynch-Day; Yong Ma; Fernando Macian; Jeffrey P MacKeigan; Kay F Macleod; Frank Madeo; Luigi Maiuri; Maria Chiara Maiuri; Davide Malagoli; May Christine V Malicdan; Walter Malorni; Na Man; Eva-Maria Mandelkow; Stéphen Manon; Irena Manov; Kai Mao; Xiang Mao; Zixu Mao; Philippe Marambaud; Daniela Marazziti; Yves L Marcel; Katie Marchbank; Piero Marchetti; Stefan Marciniak; Mateus Marcondes; Mohsen Mardi; Gabriella Marfe; Guillermo Mariño; Maria Markaki; Mark R Marten; Seamus J Martin; Camille Martinand-Mari; Wim Martinet; Marta Martinez-Vicente; Matilde Masini; Paola Matarrese; Saburo Matsuo; Raffaele Matteoni; Andreas Mayer; Nathalie M Mazure; David J McConkey; Melanie J McConnell; Catherine McDermott; Christine McDonald; Gerald M McInerney; Sharon L McKenna; BethAnn McLaughlin; Pamela J McLean; Christopher R McMaster; G Angus McQuibban; Alfred J Meijer; Miriam H Meisler; Alicia Meléndez; Thomas J Melia; Gerry Melino; Maria A Mena; Javier A Menendez; Rubem F S Menna-Barreto; Manoj B Menon; Fiona M Menzies; Carol A Mercer; Adalberto Merighi; Diane E Merry; Stefania Meschini; Christian G Meyer; Thomas F Meyer; Chao-Yu Miao; Jun-Ying Miao; Paul A M Michels; Carine Michiels; Dalibor Mijaljica; Ana Milojkovic; Saverio Minucci; Clelia Miracco; Cindy Miranti; Ioannis Mitroulis; Keisuke Miyazawa; Noboru Mizushima; Baharia Mograbi; Simin Mohseni; Xavier Molero; Bertrand Mollereau; Faustino Mollinedo; Takashi Momoi; Iryna Monastyrska; Martha M Monick; Mervyn Monteiro; Michael N Moore; Rodrigo Mora; Kevin Moreau; Paula I Moreira; Yuji Moriyasu; Jorge Moscat; Serge Mostowy; Jeremy C Mottram; Tomasz Motyl; Charbel E-H Moussa; Sylviane Muller; Sylke Müller; Karl Münger; Christian Münz; Leon O Murphy; Maureen E Murphy; Antonio Musarò; Indira Mysorekar; Eiichiro Nagata; Kazuhiro Nagata; Aimable Nahimana; Usha Nair; Toshiyuki Nakagawa; Kiichi Nakahira; Hiroyasu Nakano; Hitoshi Nakatogawa; Meera Nanjundan; Naweed I Naqvi; Derek P Narendra; Masashi Narita; Miguel Navarro; Steffan Nawrocki; Taras Y Nazarko; Andriy Nemchenko; Mihai G Netea; Thomas P Neufeld; Paul A Ney; Ioannis P Nezis; Huu Phuc Nguyen; Daotai Nie; Ichizo Nishino; Corey Nislow; Ralph A Nixon; Takeshi Noda; Angelika A Noegel; Anna Nogalska; Satoru Noguchi; Lucia Notterpek; Ivana Novak; Tomoyoshi Nozaki; Nobuyuki Nukina; Thorsten Nürnberger; Beat Nyfeler; Keisuke Obara; Terry D Oberley; Salvatore Oddo; Michinaga Ogawa; Toya Ohashi; Koji Okamoto; Nancy L Oleinick; F Javier Oliver; Laura J Olsen; Stefan Olsson; Onya Opota; Timothy F Osborne; Gary K Ostrander; Kinya Otsu; Jing-hsiung James Ou; Mireille Ouimet; Michael Overholtzer; Bulent Ozpolat; Paolo Paganetti; Ugo Pagnini; Nicolas Pallet; Glen E Palmer; Camilla Palumbo; Tianhong Pan; Theocharis Panaretakis; Udai Bhan Pandey; Zuzana Papackova; Issidora Papassideri; Irmgard Paris; Junsoo Park; Ohkmae K Park; Jan B Parys; Katherine R Parzych; Susann Patschan; Cam Patterson; Sophie Pattingre; John M Pawelek; Jianxin Peng; David H Perlmutter; Ida Perrotta; George Perry; Shazib Pervaiz; Matthias Peter; Godefridus J Peters; Morten Petersen; Goran Petrovski; James M Phang; 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Bärbel Rohrer; Igor B Roninson; Kirill Rosen; Magdalena M Rost-Roszkowska; Mustapha Rouis; Kasper M A Rouschop; Francesca Rovetta; Brian P Rubin; David C Rubinsztein; Klaus Ruckdeschel; Edmund B Rucker; Assaf Rudich; Emil Rudolf; Nelson Ruiz-Opazo; Rossella Russo; Tor Erik Rusten; Kevin M Ryan; Stefan W Ryter; David M Sabatini; Junichi Sadoshima; Tapas Saha; Tatsuya Saitoh; Hiroshi Sakagami; Yasuyoshi Sakai; Ghasem Hoseini Salekdeh; Paolo Salomoni; Paul M Salvaterra; Guy Salvesen; Rosa Salvioli; Anthony M J Sanchez; José A Sánchez-Alcázar; Ricardo Sánchez-Prieto; Marco Sandri; Uma Sankar; Poonam Sansanwal; Laura Santambrogio; Shweta Saran; Sovan Sarkar; Minnie Sarwal; Chihiro Sasakawa; Ausra Sasnauskiene; Miklós Sass; Ken Sato; Miyuki Sato; Anthony H V Schapira; Michael Scharl; Hermann M Schätzl; Wiep Scheper; Stefano Schiaffino; Claudio Schneider; Marion E Schneider; Regine Schneider-Stock; Patricia V Schoenlein; Daniel F Schorderet; Christoph Schüller; Gary K Schwartz; Luca Scorrano; 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Wolfdieter Springer; Srinivasa M Srinivasula; Leonidas Stefanis; Joan S Steffan; Ruediger Stendel; Harald Stenmark; Anastasis Stephanou; Stephan T Stern; Cinthya Sternberg; Björn Stork; Peter Strålfors; Carlos S Subauste; Xinbing Sui; David Sulzer; Jiaren Sun; Shi-Yong Sun; Zhi-Jun Sun; Joseph J Y Sung; Kuninori Suzuki; Toshihiko Suzuki; Michele S Swanson; Charles Swanton; Sean T Sweeney; Lai-King Sy; Gyorgy Szabadkai; Ira Tabas; Heinrich Taegtmeyer; Marco Tafani; Krisztina Takács-Vellai; Yoshitaka Takano; Kaoru Takegawa; Genzou Takemura; Fumihiko Takeshita; Nicholas J Talbot; Kevin S W Tan; Keiji Tanaka; Kozo Tanaka; Daolin Tang; Dingzhong Tang; Isei Tanida; Bakhos A Tannous; Nektarios Tavernarakis; Gregory A Taylor; Graham S Taylor; J Paul Taylor; Lance S Terada; Alexei Terman; Gianluca Tettamanti; Karin Thevissen; Craig B Thompson; Andrew Thorburn; Michael Thumm; FengFeng Tian; Yuan Tian; Glauco Tocchini-Valentini; Aviva M Tolkovsky; Yasuhiko Tomino; Lars Tönges; Sharon A Tooze; Cathy Tournier; John Tower; Roberto Towns; Vladimir Trajkovic; Leonardo H Travassos; Ting-Fen Tsai; Mario P Tschan; Takeshi Tsubata; Allan Tsung; Boris Turk; Lorianne S Turner; Suresh C Tyagi; Yasuo Uchiyama; Takashi Ueno; Midori Umekawa; Rika Umemiya-Shirafuji; Vivek K Unni; Maria I Vaccaro; Enza Maria Valente; Greet Van den Berghe; Ida J van der Klei; Wouter van Doorn; Linda F van Dyk; Marjolein van Egmond; Leo A van Grunsven; Peter Vandenabeele; Wim P Vandenberghe; Ilse Vanhorebeek; Eva C Vaquero; Guillermo Velasco; Tibor Vellai; Jose Miguel Vicencio; Richard D Vierstra; Miquel Vila; Cécile Vindis; Giampietro Viola; Maria Teresa Viscomi; Olga V Voitsekhovskaja; Clarissa von Haefen; Marcela Votruba; Keiji Wada; Richard Wade-Martins; Cheryl L Walker; Craig M Walsh; Jochen Walter; Xiang-Bo Wan; Aimin Wang; Chenguang Wang; Dawei Wang; Fan Wang; Fen Wang; Guanghui Wang; Haichao Wang; Horng-Dar Wang; Hong-Gang Wang; Jin Wang; Ke Wang; Mei Wang; Richard C Wang; Xinglong Wang; Xuejun Wang; Yipeng Wang; Ying-Jan Wang; Zhen Wang; Zhinong Wang; Zhigang Charles Wang; Derick G Wansink; Diane M Ward; Hirotaka Watada; Sarah L Waters; Paul Webster; Lixin Wei; Conrad C Weihl; William A Weiss; Scott M Welford; Long-Ping Wen; Caroline A Whitehouse; J Lindsay Whitton; Alexander J Whitworth; Tom Wileman; John W Wiley; Simon Wilkinson; Dieter Willbold; Roger L Williams; Peter R Williamson; Bradly G Wouters; Chenghan Wu; Dao-Cheng Wu; William K K Wu; Andreas Wyttenbach; Ramnik J Xavier; Zhijun Xi; Pu Xia; Gengfu Xiao; Zhiping Xie; Zhonglin Xie; Da-zhi Xu; Jianzhen Xu; Liang Xu; Xiaolei Xu; Ai Yamamoto; Akitsugu Yamamoto; Shunhei Yamashina; Michiaki Yamashita; Xianghua Yan; Mitsuhiro Yanagida; Dun-Sheng Yang; Elizabeth Yang; Jin-Ming Yang; Shi Yu Yang; Wannian Yang; Wei Yuan Yang; Zhifen Yang; Meng-Chao Yao; Tso-Pang Yao; Behzad Yeganeh; Wei-Lien Yen; Jia-jing Yin; Xiao-Ming Yin; Ook-Joon Yoo; Gyesoon Yoon; Seung-Yong Yoon; Tomohiro Yorimitsu; Yuko Yoshikawa; Tamotsu Yoshimori; Kohki Yoshimoto; Ho Jin You; Richard J Youle; 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Maho Hamasaki; Feng Han; Ting Han; Michael K Hancock; Malene Hansen; Hisashi Harada; Masaru Harada; Stefan E Hardt; J Wade Harper; Adrian L Harris; James Harris; Steven D Harris; Marie-Joseé Hébert; Kim A Heidenreich; Miep H Helfrich; Gudmundur V Helgason; Elizabeth P Henske; Brian Herman; Paul K Herman; Claudio Hetz; Sabine Hilfiker; Joseph A Hill; Lynne J Hocking; Paul Hofman; Thomas G Hofmann; Jörg Höhfeld; Tessa L Holyoake; Ming-Huang Hong; David A Hood; Gökhan S Hotamisligil; Ewout J Houwerzijl; Maria Høyer-Hansen; Bingren Hu; Chien-An A Hu; Hong-Ming Hu; Ya Hua; Canhua Huang; Ju Huang; Shengbing Huang; Wei-Pang Huang; Tobias B Huber; Won-Ki Huh; Tai-Ho Hung; Ted R Hupp; Gang Min Hur; James B Hurley; Sabah N A Hussain; Patrick J Hussey; Jung Jin Hwang; Seungmin Hwang; Atsuhiro Ichihara; Shirin Ilkhanizadeh; Ken Inoki; Takeshi Into; Valentina Iovane; Juan L Iovanna; Nancy Y Ip; Yoshitaka Isaka; Hiroyuki Ishida; Ciro Isidoro; Ken-ichi Isobe; Akiko Iwasaki; Marta Izquierdo; Yotaro Izumi; Panu M Jaakkola; Marja Jäättelä; George R Jackson; William T Jackson; Bassam Janji; Marina Jendrach; Ju-Hong Jeon; Eui-Bae Jeung; Hong Jiang; Hongchi Jiang; Jean X Jiang; Ming Jiang; Qing Jiang; Xuejun Jiang; Xuejun Jiang; Alberto Jiménez; Meiyan Jin; Shengkan Jin; Cheol O Joe; Terje Johansen; Daniel E Johnson; Gail V W Johnson; Nicola L Jones; Bertrand Joseph; Suresh K Joseph; Annie M Joubert; Gábor Juhász; Lucienne Juillerat-Jeanneret; Chang Hwa Jung; Yong-Keun Jung; Kai Kaarniranta; Allen Kaasik; Tomohiro Kabuta; Motoni Kadowaki; Katarina Kagedal; Yoshiaki Kamada; Vitaliy O Kaminskyy; Harm H Kampinga; Hiromitsu Kanamori; Chanhee Kang; Khong Bee Kang; Kwang Il Kang; Rui Kang; Yoon-A Kang; Tomotake Kanki; Thirumala-Devi Kanneganti; Haruo Kanno; Arthi Kanthasamy; Anumantha G Kanthasamy; Vassiliki Karantza; Gur P Kaushal; Susmita Kaushik; Yoshinori Kawazoe; Po-Yuan Ke; John H Kehrl; Ameeta Kelekar; Claus Kerkhoff; David Kessel; Hany Khalil; Jan A K W Kiel; Amy A Kiger; Akio Kihara; Do-Hyung Kim; Dong-Hou Kim; Deok Ryong Kim; Eun-Kyoung Kim; Hyung-Ryong Kim; Jin Cheon Kim; Jeong Hun Kim; John K Kim; Jae-Sung Kim; Peter K Kim; Seong Who Kim; Yonghyun Kim; Yong-Sun Kim; Adi Kimchi; Alec C Kimmelman; Jason S King; Timothy J Kinsella; Vladimir Kirkin; Lorrie A Kirshenbaum; Katsuhiko Kitamoto; Kaio Kitazato; Ludger Klein; Walter T Klimecki; Giuseppe Arancia; John P Aris; Katsuhiko Asanuma; Nana Y O Asare; Hisashi Ashida; Valerie Askanas; David S Askew; Henry N Ginsberg; Jakub Golab; Michael S Goligorsky; Pierre Golstein; Candelaria Gomez-Manzano; Makoto Hashimoto; Jeffrey A Haspel; Shin-ichiro Hayashi; Lori A Hazelhurst; Congcong He; You-Wen He; Brian Zuckerbraun
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy 2012;8(4):445-544.
2012: Celia Quijano; Hector Romero; Ilsa I Rovira; Liu Cao; Maria M Fergusson; Sarah Gutkind; Edward D Karoly; Jie Liu; Robert P Mohney; TOREN FINKEL
Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.
Cell cycle (Georgetown, Tex.) 2012;11(7):1383-92.
2012: TOREN FINKEL
From sulfenylation to sulfhydration: what a thiolate needs to tolerate.
Science signaling 2012;5(215):pe10.
2012: TOREN FINKEL
Signal transduction by mitochondrial oxidants.
The Journal of biological chemistry 2012;287(7):4434-40.
2011: Jie Liu; Liu Cao; TOREN FINKEL
Oxidants, metabolism, and stem cell biology.
Free radical biology & medicine 2011;51(12):2158-62.
2011: Jinhua Shen; Wen-Mei Yu; TOREN FINKEL; Milou Groot Nibbelink; Caiying Guo; Jie Liu; Xia Liu; Cheng-Kui Qu
A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells.
Molecular and cellular biology 2011;31(24):4902-16.
2011: Matthew Pfeiffer; Margaret M Sedensky; Sarah J Wu; Xianmei Yang; Phil G Morgan; Ellen Abramson; Catherine F Clarke; TOREN FINKEL; Ernst-Bernhard Kayzer; M Alexander Kenaston; Cory U Lago; Herng-Hsiang Lo; Adam Lunceford; Chris McLeod; Edward M Mills
Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.
The Journal of biological chemistry 2011;286(43):37712-20.
2011: Andrey Parkhitko; J Julia Wu; Jane J Yu; Neil Auricchio; TOREN FINKEL; Khadijah M Hindi; Magdalena Karbowniczek; David J Kwiatkowski; Tasha A Morrison; Faina Myachina; Elizabeth Petri Henske
Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(30):12455-60.
2011: TOREN FINKEL
Signal transduction by reactive oxygen species.
The Journal of cell biology 2011;194(1):7-15.
2011: Hariom Yadav; Patricia Zerfas; Duan Zhigang; Monica Skarulis; Christina Stuelten; Anne E Sumner; Peter Sun; Elizabeth C Wright; Weiping Chen; TOREN FINKEL; Oksana Gavrilova; Anil K Kamaraju; Scott Lonning; Rana Malek; Celia Quijano; Sushil G Rane
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling.
Cell metabolism 2011;14(1):67-79.
2011: TOREN FINKEL; Arshed A Quyyumi
Genetic links between circulating cells and cardiovascular risk.
Circulation. Cardiovascular genetics 2011;4(3):218-20.
2011: TOREN FINKEL
Telomeres and mitochondrial function.
Circulation research 2011;108(8):903-4.
2011: Praphulla C Shukla; Adrian Quan; Bobby Yanagawa; Krishna K Singh; Hwee Teoh; Ilsa I Rovira; Howard Leong-Poi; Yi Pan; Fina Lovren; Aanika Gupta; John G Coles; Thomas G Parker; Christine Brezden-Masley; William L Stanford; TOREN FINKEL; Chu-Xia Deng; Liu Cao; Mohammed Al-Omran; Michael D Schneider; Subodh Verma
BRCA1 is an essential regulator of heart function and survival following myocardial infarction.
Nature communications 2011;2():593.
2011: Hongjun Liu; Maria M Fergusson; J Julie Wu; Ilsa I Rovira; Jie Liu; Oksana Gavrilova; Teng Lu; Jianjun Bao; Donghe Han; Michael N Sack; TOREN FINKEL
Wnt signaling regulates hepatic metabolism.
Science signaling 2011;4(158):ra6.
2010: J Julie Wu; Celia Quijano; Jiamei Wang; TOREN FINKEL
Metabolism meets autophagy.
Cell cycle (Georgetown, Tex.) 2010;9(24):4780-1.
2010: Serpil Erzurum; Sharon I Rounds; Troy Stevens; Micheala Aldred; Jason Aliotta; Stephen L Archer; Kewal Asosingh; Robert Balaban; Natalie Bauer; Jahar Bhattacharya; Harm Bogaard; Gaurav Choudhary; Gerald W Dorn; Raed Dweik; Karen Fagan; Michael Fallon; TOREN FINKEL; Mark Geraci; Mark T Gladwin; Paul M Hassoun; Marc Humbert; Naftali Kaminski; Steven M Kawut; Joseph Loscalzo; Donald McDonald; Ivan F McMurtry; John Newman; Mark Nicolls; Marlene Rabinovitch; Judy Shizuru; Masahiko Oka; Peter Polgar; David Rodman; Paul Schumacker; Kurt Stenmark; Rubin M Tuder; Norbert Voelkel; Eugene Sullivan; Richard Weinshilboum; Mervin C Yoder; Yingming Zhao; Dorothy Gail; Timothy M Moore
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
American journal of respiratory and critical care medicine 2010;182(12):1554-62.
2010: Samuel F Bunting; Elsa Callén; Nancy Wong; Hua-Tang Chen; Federica Polato; Amanda Gunn; Anne Bothmer; Niklas Feldhahn; Oscar Fernandez-Capetillo; Liu Cao; Xiaoling Xu; Chu-Xia Deng; TOREN FINKEL; Michel C Nussenzweig; Jeremy M Stark; André Nussenzweig
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Cell 2010;141(2):243-54.
2010: Mikhail V Blagosklonny; Judy Campisi; David A Sinclair; Andrzej Bartke; Maria A Blasco; William M Bonner; Vilhelm A Bohr; Robert M Brosh; Anne Brunet; Ronald A Depinho; Lawrence A Donehower; Caleb E Finch; TOREN FINKEL; Myriam Gorospe; Andrei V Gudkov; Michael N Hall; Siegfried Hekimi; Stephen L Helfand; Jan Karlseder; Cynthia Kenyon; Guido Kroemer; Valter Longo; Andre Nussenzweig; Heinz D Osiewacz; Daniel S Peeper; Thomas A Rando; K Lenhard Rudolph; Paolo Sassone-Corsi; Manuel Serrano; Norman E Sharpless; Vladimir P Skulachev; Jonathan L Tilly; John Tower; Eric Verdin; Jan Vijg
Impact papers on aging in 2009.
Aging 2010;2(3):111-21.
2009: Edmund Chen; TOREN FINKEL
Preview. The Tortoise, the hare, and the FoxO.
Cell stem cell 2009;5(5):451-2.
2009: Toshio Ohtsubo; Kiyoshi Matsumura; Kanae Sakagami; Koji Fujii; Kazuhiko Tsuruya; Hideko Noguchi; Ilsa I Rovira; TOREN FINKEL; Mitsuo Iida
Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.
Hypertension 2009;54(4):868-76.
2009: Leslie G Biesecker; James C Mullikin; Flavia M Facio; Clesson Turner; Praveen F Cherukuri; Robert W Blakesley; Gerald Bouffard; Peter S Chines; Pedro Cruz; Nancy F Hansen; Jamie K Teer; Baishali Maskeri; Alice C Young; Teri A Manolio; Alexander F Wilson; TOREN FINKEL; PAUL HWANG; Andrew Arai; Alan T Remaley; Vandana Sachdev; Robert Shamburek; Richard O Cannon; Eric Green
The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine.
Genome research 2009;19(9):1665-74.
2009: Liu Cao; Xioaling Xu; Samuel F Bunting; Jie Liu; Rui-Hong Wang; Longyue L Cao; J Julie Wu; Tie-Nan Peng; Junjie Chen; Andre Nussenzweig; Chu-Xia Deng; TOREN FINKEL
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Molecular cell 2009;35(4):534-41.
2009: TOREN FINKEL; Chu-Xia Deng; Raul Mostoslavsky
Recent progress in the biology and physiology of sirtuins.
Nature 2009;460(7255):587-91.
2009: TOREN FINKEL; PAUL HWANG
The Krebs cycle meets the cell cycle: mitochondria and the G1-S transition.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):11825-6.
2009: Jie Liu; Liu Cao; Jichun Chen; Shiwei Song; In Hye Lee; Celia Quijano; Hongjun Liu; Keyvan Keyvanfar; Haoqian Chen; Long-Yue Cao; Bong-Hyun Ahn; Neil G Kumar; Ilsa I Rovira; Xiao-Ling Xu; Maarten van Lohuizen; Noboru Motoyama; Chu-Xia Deng; TOREN FINKEL
Bmi1 regulates mitochondrial function and the DNA damage response pathway.
Nature 2009;459(7245):387-92.
2009: J Julie Wu; Celia Quijano; Edmund Chen; Hongjun Liu; Liu Cao; Maria M Fergusson; Ilsa I Rovira; Sarah Gutkind; Mathew P Daniels; Masaaki Komatsu; TOREN FINKEL
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy.
Aging 2009;1(4):425-37.
2009: In Hye Lee; TOREN FINKEL
Regulation of autophagy by the p300 acetyltransferase.
The Journal of biological chemistry 2009;284(10):6322-8.
2009: TOREN FINKEL
Breathing lessons: Tor tackles the mitochondria.
Aging 2009;1(1):9-11.
2008: Stefan M Schieke; Mingchao Ma; Liu Cao; J Philip McCoy; Chengyu Liu; Nancy Hensel; A John Barrett; Manfred Boehm; TOREN FINKEL
Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells.
The Journal of biological chemistry 2008;283(42):28506-12.
2008: Rui-Hong Wang; Yin Zheng; Hyun-Seok Kim; Xiaoling Xu; Liu Cao; Tyler Luhasen; Mi-Hye Lee; Cuiying Xiao; Athanassios Vassilopoulos; Weiping Chen; Kevin Gardner; Yan-Gao Man; Mien-Chie Hung; TOREN FINKEL; Chu-Xia Deng
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.
Molecular cell 2008;32(1):11-20.
2008: Bong-Hyun Ahn; Hyun-Seok Kim; Shiwei Song; In Hye Lee; Jie Liu; Athanassios Vassilopoulos; Chu-Xia Deng; TOREN FINKEL
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14447-52.
2008: Xing-Jie Liang; TOREN FINKEL; Ding-Wu Shen; Jun-Jie Yin; Adorjan Aszalos; Michael M Gottesman
SIRT1 contributes in part to cisplatin resistance in cancer cells by altering mitochondrial metabolism.
Molecular cancer research : MCR 2008;6(9):1499-506.
2008: Yvonne M W Janssen-Heininger; Brooke T Mossman; Nicholas H Heintz; Henry J Forman; Balaraman Kalyanaraman; TOREN FINKEL; Jonathan S Stamler; Sue Goo Rhee; Albert van der Vliet
Redox-based regulation of signal transduction: principles, pitfalls, and promises.
Free radical biology & medicine 2008;45(1):1-17.
2008: Stefan M Schieke; J Philip McCoy; TOREN FINKEL
Coordination of mitochondrial bioenergetics with G1 phase cell cycle progression.
Cell cycle (Georgetown, Tex.) 2008;7(12):1782-7.
2008: Teng Lu; TOREN FINKEL
Free radicals and senescence.
Experimental cell research 2008;314(9):1918-22.
2008: In Hye Lee; Liu Cao; Raul Mostoslavsky; David Lombard; Jie Liu; Nicholas E Bruns; Maria Tsokos; Frederick W Alt; TOREN FINKEL
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3374-9.
2007: TOREN FINKEL; Manuel Serrano; Maria A Blasco
The common biology of cancer and ageing.
Nature 2007;448(7155):767-74.
2007: Hongjun Liu; Maria M Fergusson; Rogerio M Castilho; Jie Liu; Liu Cao; Jichun Chen; Daniela Malide; Ilsa I Rovira; Daniel Schimel; Calvin J Kuo; J Silvio Gutkind; PAUL HWANG; TOREN FINKEL
Augmented Wnt signaling in a mammalian model of accelerated aging.
Science (New York, N.Y.) 2007;317(5839):803-6.
2007: Shiwei Song; TOREN FINKEL
GAPDH and the search for alternative energy.
Nature cell biology 2007;9(8):869-70.
2007: Stefan M Schieke; TOREN FINKEL
TOR and aging: less is more.
Cell metabolism 2007;5(4):233-5.
2007: Kevin J Cheung; Iphigenia Tzameli; Pavlos Pissios; Ilsa Rovira; Oksana Gavrilova; Toshio Ohtsubo; Zhu Chen; TOREN FINKEL; Jeffrey S Flier; Jeffrey M Friedman
Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity.
Cell metabolism 2007;5(2):115-28.
2006: Liu Cao; TOREN FINKEL
Cancer gets the Chk'ered flag.
Nature medicine 2006;12(12):1354-6.
2006: TOREN FINKEL
Cell biology: a clean energy programme.
Nature 2006;444(7116):151-2.
2006: Stefan M Schieke; TOREN FINKEL
Mitochondrial signaling, TOR, and life span.
Biological chemistry 2006;387(10-11):1357-61.
2006: Stefan M Schieke; Darci Phillips; J Philip McCoy; Angel M Aponte; Rong-Fong Shen; Robert Balaban; TOREN FINKEL
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity.
The Journal of biological chemistry 2006;281(37):27643-52.
2006: TOREN FINKEL
Intracellular redox regulation by the family of small GTPases.
Antioxidants & redox signaling 2006;8(9-10):1857-63.
2006: Chuangui Wang; Lihong Chen; Xinghua Hou; Zhenyu Li; Neha Kabra; Yihong Ma; Shino Nemoto; TOREN FINKEL; Wei Gu; W.Douglas Cress; Jiandong Chen
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.
Nature cell biology 2006;8(9):1025-31.
2006: Aarif Y Khakoo; Shibani Pati; Stasia A Anderson; William Reid; Mohamed F Elshal; Ilsa I Rovira; Ahn T Nguyen; Daniela Malide; Christian A Combs; Gentzon Hall; Jianhu Zhang; Mark Raffeld; Terry B Rogers; William Stetler-Stevenson; Joseph A Frank; Marvin Reitz; TOREN FINKEL
Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
The Journal of experimental medicine 2006;203(5):1235-47.
2006: TOREN FINKEL; Jan Vijg; Jerry W Shay
Time, tumours and telomeres. Meeting on Cancer and Aging.
EMBO reports 2006;7(5):479-83.
2006: Shino Nemoto; Christian A Combs; Stephanie French; Bong-Hyun Ahn; Maria M Fergusson; Robert Balaban; TOREN FINKEL
The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism.
The Journal of biological chemistry 2006;281(15):10555-60.
2006: Jie Liu; TOREN FINKEL
Stem cell aging: what bleach can teach.
Nature medicine 2006;12(4):383-4.
2005: TOREN FINKEL
Radical medicine: treating ageing to cure disease.
Nature reviews. Molecular cell biology 2005;6(12):971-6.
2005: Hongjun Liu; Renata Colavitti; Ilsa I Rovira; TOREN FINKEL
Redox-dependent transcriptional regulation.
Circulation research 2005;97(10):967-74.
2005: Wanli Smith; Darrell D Norton; Myriam Gorospe; Haibing Jiang; Shino Nemoto; Nikki J Holbrook; TOREN FINKEL; John W Kusiak
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
The Journal of cell biology 2005;169(2):331-9.
2005: Shino Nemoto; Maria M Fergusson; TOREN FINKEL
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.
The Journal of biological chemistry 2005;280(16):16456-60.
2005: Renata Colavitti; TOREN FINKEL
Reactive oxygen species as mediators of cellular senescence.
IUBMB life 2005;57(4-5):277-81.
2005: Robert Balaban; Shino Nemoto; TOREN FINKEL
Mitochondria, oxidants, and aging.
Cell 2005;120(4):483-95.
2005: Tiffany M Powell; Jonathan D Paul; Jonathan M Hill; Michael Thompson; Moshe Benjamin; Maria Rodrigo; J Philip McCoy; Elizabeth J Read; Hanh M Khuu; Susan F Leitman; TOREN FINKEL; Richard O Cannon
Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(2):296-301.
2005: Yukitaka Shizukuda; Richard L Piekarz; Susan E Bates; Vandana Sachdev; TOREN FINKEL; Douglas R Rosing
Effect of a histone deacetylase inhibitor on human cardiac mass.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2005;19(1):89-90.
2005: Aarif Y Khakoo; TOREN FINKEL
Endothelial progenitor cells.
Annual review of medicine 2005;56():79-101.
2004: Shino Nemoto; Maria M Fergusson; TOREN FINKEL
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.
Science (New York, N.Y.) 2004;306(5704):2105-8.
2004: Toshio Ohtsubo; Ilsa I Rovira; Matthew F Starost; Chengyu Liu; TOREN FINKEL
Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.
Circulation research 2004;95(11):1118-24.
2004: Jonathan M Hill; TOREN FINKEL; Arshed A Quyyumi
Endothelial progenitor cells and endothelial dysfunction.
Vox sanguinis 2004;87 Suppl 2():31-7.
2004: Shino Nemoto; TOREN FINKEL
Ageing and the mystery at Arles.
Nature 2004;429(6988):149-52.
2003: Edward M Mills; Matthew L Banks; Jon E Sprague; TOREN FINKEL
Pharmacology: uncoupling the agony from ecstasy.
Nature 2003;426(6965):403-4.
2003: TOREN FINKEL
Ageing: a toast to long life.
Nature 2003;425(6954):132-3.
2003: TOREN FINKEL
Oxidant signals and oxidative stress.
Current opinion in cell biology 2003;15(2):247-54.
2003: Jonathan M Hill; Gloria Zalos; julian halcox; William H Schenke; Myron A Waclawiw; Arshed A Quyyumi; TOREN FINKEL
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk.
The New England journal of medicine 2003;348(7):593-600.
2003: TOREN FINKEL
Neutrophils with a license to kill: permeabilized, not stirred.
Developmental cell 2003;4(2):146-8.
2002: Masaru Ichida; Shino Nemoto; TOREN FINKEL
Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor gamma Coactivator-1 alpha (PGC-1alpha).
The Journal of biological chemistry 2002;277(52):50991-5.
2002: Edward M Mills; Dong Xu; Maria M Fergusson; Christian A Combs; Yuhui Xu; TOREN FINKEL
Regulation of cellular oncosis by uncoupling protein 2.
The Journal of biological chemistry 2002;277(30):27385-92.
2002: Duy T Nguyen; Ilsa I Rovira; TOREN FINKEL
Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A.
FEBS letters 2002;521(1-3):170-4.
2002: Dong Xu; TOREN FINKEL
A role for mitochondria as potential regulators of cellular life span.
Biochemical and biophysical research communications 2002;294(2):245-8.
2002: Pavel A Savitsky; TOREN FINKEL
Redox regulation of Cdc25C.
The Journal of biological chemistry 2002;277(23):20535-40.
2002: Shino Nemoto; TOREN FINKEL
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway.
Science (New York, N.Y.) 2002;295(5564):2450-2.
2002: Dong Xu; Ilsa I Rovira; TOREN FINKEL
Oxidants painting the cysteine chapel: redox regulation of PTPs.
Developmental cell 2002;2(3):251-2.
2002: Daniel M Sullivan; Rodney L Levine; TOREN FINKEL
Detection and affinity purification of oxidant-sensitive proteins using biotinylated glutathione ethyl ester.
Methods in enzymology 2002;353():101-13.
2001: TOREN FINKEL
Reactive oxygen species and signal transduction.
IUBMB life 2001;52(1-2):3-6.
2001: M Ichida; TOREN FINKEL
Ras regulates NFAT3 activity in cardiac myocytes.
The Journal of biological chemistry 2001;276(5):3524-30.
2000: TOREN FINKEL; N J Holbrook
Oxidants, oxidative stress and the biology of ageing.
Nature 2000;408(6809):239-47.
2000: S Nemoto; K Takeda; Z X Yu; V J Ferrans; TOREN FINKEL
Role for mitochondrial oxidants as regulators of cellular metabolism.
Molecular and cellular biology 2000;20(19):7311-8.
2000: Daniel M Sullivan; Nancy B Wehr; Maria M Fergusson; Rodney L Levine; TOREN FINKEL
Identification of oxidant-sensitive proteins: TNF-alpha induces protein glutathiolation.
Biochemistry 2000;39(36):11121-8.
2000: TOREN FINKEL
Redox-dependent signal transduction.
FEBS letters 2000;476(1-2):52-4.
2000: E Hsich; B H Segal; Patrick J Pagano; Federico E Rey; Beverly Paigen; J Deleonardis; Robert F Hoyt; S M Holland; TOREN FINKEL
Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.
Circulation 2000;101(11):1234-6.
2000: D Xu; R Neville; TOREN FINKEL
Homocysteine accelerates endothelial cell senescence.
FEBS letters 2000;470(1):20-4.
2000: Eduardo Marban; Roberto Bolli; G Breitwieser; R Busse; H Dietz; M Endoh; TOREN FINKEL; David A Kass; Charles J Lowenstein; M Rabinovitch; Gordon F Tomaselli
Under new management: A six-month progress report on Circulation Research.
Circulation research 2000;86(2):111-3.
2000: Daniel M Sullivan; TOREN FINKEL
Expression of Rho GTPases using adenovirus vectors.
Methods in enzymology 2000;325():303-14.
1999: H Ito; Ilsa I Rovira; MIchael Bloom; Kazuyo Takeda; Victor J Ferrans; Arshed A Quyyumi; TOREN FINKEL
Endothelial progenitor cells as putative targets for angiostatin.
Cancer research 1999;59(23):5875-7.
1999: Yi Fu Zhou; Matie Shou; Esther Guetta; R Guzman; EF Unger; Z X Yu; J Zhang; TOREN FINKEL; Stephen E Epstein
Cytomegalovirus infection of rats increases the neointimal response to vascular injury without consistent evidence of direct infection of the vascular wall.
Circulation 1999;100(14):1569-75.
1999: A Li; Abhiram Prasad; Rita A Mincemoyer; Colleen L Satorius; Neal Epstein; TOREN FINKEL; Arshed A Quyyumi
Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.
American journal of medical genetics 1999;86(1):57-61.
1999: A E Li; H Ito; Ilsa I Rovira; KS Kim; Kazuyo Takeda; Z Y Yu; Victor J Ferrans; TOREN FINKEL
A role for reactive oxygen species in endothelial cell anoikis.
Circulation research 1999;85(4):304-10.
1999: DD Hegland; D M Sullivan; Ilsa I Rovira; A Li; Imre Kovesdi; JT Bruder; TOREN FINKEL
Regulation of endothelial cell adherens junctions by a Ras-dependent signal transduction pathway.
Biochemical and biophysical research communications 1999;260(2):371-6.
1999: TOREN FINKEL
Thinking globally, acting locally. The promise of cardiovascular gene therapy.
Circulation research 1999;84(12):1471-2.
1999: TOREN FINKEL
Myocyte hypertrophy: the long and winding RhoA'd.
The Journal of clinical investigation 1999;103(12):1619-20.
1999: K Tanaka; Jian-Ping Zou; K Takeda; V J Ferrans; GORDON SANDFORD; T M Johnson; TOREN FINKEL; Stephen E Epstein
Effects of human cytomegalovirus immediate-early proteins on p53-mediated apoptosis in coronary artery smooth muscle cells.
Circulation 1999;99(13):1656-9.
1999: A C Lee; Brett Fenster; H Ito; Kazuyo Takeda; Nancy S Bae; Tazuko H Hirai; Zu-Xi Yu; Victor J Ferrans; Bruce H Howard; TOREN FINKEL
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species.
The Journal of biological chemistry 1999;274(12):7936-40.
1999: TOREN FINKEL
Signal transduction by reactive oxygen species in non-phagocytic cells.
Journal of leukocyte biology 1999;65(3):337-40.
1999: AM Doanes; DD Hegland; R Sethi; Imre Kovesdi; JT Bruder; TOREN FINKEL
VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases.
Biochemical and biophysical research communications 1999;255(2):545-8.
1999: Leni Moldovan; K Irani; Nicanor I Moldovan; TOREN FINKEL; Pascal J Goldschmidt-Clermont
The actin cytoskeleton reorganization induced by Rac1 requires the production of superoxide.
Antioxidants & redox signaling 1999;1(1):29-43.
1998: K Tanaka; JB Pracyk; Kazuyo Takeda; Zu-Xi Yu; Victor J Ferrans; Shailesh S Deshpande; Michitaka Ozaki; PAUL HWANG; Charles J Lowenstein; Kaikobad Irani; TOREN FINKEL
Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism.
The Journal of biological chemistry 1998;273(40):25922-8.
1998: JB Pracyk; K Tanaka; DD Hegland; KS Kim; R Sethi; Ilsa I Rovira; D R Blazina; L Lee; JT Bruder; Imre Kovesdi; P J Goldshmidt-Clermont; Kaikobad Irani; TOREN FINKEL
A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.
The Journal of clinical investigation 1998;102(5):929-37.
1998: AM Doanes; Kaikobad Irani; Pascal J Goldschmidt-Clermont; TOREN FINKEL
A requirement for rac1 in the PDGF-stimulated migration of fibroblasts and vascular smooth cells.
Biochemistry and molecular biology international 1998;45(2):279-87.
1998: L Lee; K Irani; TOREN FINKEL
Bcl-2 regulates nonapoptotic signal transduction: inhibition of c-Jun N-terminal kinase (JNK) activation by IL-1 beta and hydrogen peroxide.
Molecular genetics and metabolism 1998;64(1):19-24.
1998: KS Kim; Kazuyo Takeda; R Sethi; JB Pracyk; K Tanaka; Y F Zhou; Zu-Xi Yu; Victor J Ferrans; JT Bruder; Imre Kovesdi; Kaikobad Irani; Pascal J Goldschmidt-Clermont; TOREN FINKEL
Protection from reoxygenation injury by inhibition of rac1.
The Journal of clinical investigation 1998;101(9):1821-6.
1998: TOREN FINKEL
Oxygen radicals and signaling.
Current opinion in cell biology 1998;10(2):248-53.
1997: K A Moore; R Sethi; AM Doanes; T M Johnson; JB Pracyk; M Kirby; Kaikobad Irani; Pascal J Goldschmidt-Clermont; TOREN FINKEL
Rac1 is required for cell proliferation and G2/M progression.
The Biochemical journal 1997;326 ( Pt 1)():17-20.
1997: R L Harrell; S Rajanayagam; AM Doanes; R J Guzman; E A Hirschowitz; R G Crystal; Stephen E Epstein; TOREN FINKEL
Inhibition of vascular smooth muscle cell proliferation and neointimal accumulation by adenovirus-mediated gene transfer of cytosine deaminase.
Circulation 1997;96(2):621-7.
1997: Kaikobad Irani; Y Xia; Jay L Zweier; STEVEN SOLLOTT; Channing J Der; Eric R Fearon; M Sundaresan; TOREN FINKEL; Pascal J Goldschmidt-Clermont
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts.
Science (New York, N.Y.) 1997;275(5306):1649-52.
1997: Nicanor I Moldovan; Erin Milliken; K Irani; J Chen; R H Sohn; TOREN FINKEL; Pascal J Goldschmidt-Clermont
Regulation of endothelial cell adhesion by profilin.
Current biology : CB 1997;7(1):24-30.
1996: D J Sulciner; Kaikobad Irani; Zu-Xi Yu; Victor J Ferrans; Pascal J Goldschmidt-Clermont; TOREN FINKEL
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation.
Molecular and cellular biology 1996;16(12):7115-21.
1996: S E Epstein; E Speir; Yi Fu Zhou; E Guetta; M Leon; TOREN FINKEL
The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus.
Lancet 1996;348 Suppl 1():s13-7.
1996: Yi Fu Zhou; E Guetta; Zu-Xi Yu; TOREN FINKEL; Stephen E Epstein
Human cytomegalovirus increases modified low density lipoprotein uptake and scavenger receptor mRNA expression in vascular smooth muscle cells.
The Journal of clinical investigation 1996;98(9):2129-38.
1996: L E Crawford; Erin Milliken; Kaikobad Irani; Jay L Zweier; Lewis C Becker; T M Johnson; N T Eissa; R G Crystal; TOREN FINKEL; Pascal J Goldschmidt-Clermont
Superoxide-mediated actin response in post-hypoxic endothelial cells.
The Journal of biological chemistry 1996;271(43):26863-7.
1996: T M Johnson; Zu-Xi Yu; Victor J Ferrans; R A Lowenstein; TOREN FINKEL
Reactive oxygen species are downstream mediators of p53-dependent apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11848-52.
1996: T M Johnson; Stephen E Epstein; TOREN FINKEL
Apoptosis in vascular disease: opportunities for genetic therapeutic intervention.
Seminars in interventional cardiology : SIIC 1996;1(3):195-202.
1996: M Sundaresan; Zu-Xi Yu; Victor J Ferrans; D J Sulciner; J Silvio Gutkind; Kaikobad Irani; Pascal J Goldschmidt-Clermont; TOREN FINKEL
Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.
The Biochemical journal 1996;318 ( Pt 2)():379-82.
1996: Yi Fu Zhou; Martin B Leon; Myron A Waclawiw; J J Popma; Zu-Xi Yu; TOREN FINKEL; Stephen E Epstein
Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy.
The New England journal of medicine 1996;335(9):624-30.
1995: M Sundaresan; Zu-Xi Yu; Victor J Ferrans; Kaikobad Irani; TOREN FINKEL
Requirement for generation of H2O2 for platelet-derived growth factor signal transduction.
Science (New York, N.Y.) 1995;270(5234):296-9.
1995: TOREN FINKEL; S E Epstein
Gene therapy for vascular disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(10):843-51.
1995: E Speir; Eng-Shang Huang; rama modali; M B Leon; F Shawl; TOREN FINKEL; Stephen E Epstein
Interaction of human cytomegalovirus with p53: possible role in coronary restenosis.
Scandinavian journal of infectious diseases. Supplementum 1995;99():78-81.
1994: R J Guzman; E A Hirschowitz; S L Brody; Helen-Ann Brown Epstein; Stephen E Epstein; TOREN FINKEL
In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10732-6.
1994: Kaikobad Irani; S Herzlinger; TOREN FINKEL
Ras proteins regulate multiple mitogenic pathways in A10 vascular smooth muscle cells.
Biochemical and biophysical research communications 1994;202(3):1252-8.
1994: E Speir; rama modali; Eng-Shang Huang; Martin B Leon; F Shawl; TOREN FINKEL; Stephen E Epstein
Potential role of human cytomegalovirus and p53 interaction in coronary restenosis.
Science (New York, N.Y.) 1994;265(5170):391-4.
1994: Stephen E Epstein; E Speir; EF Unger; R J Guzman; TOREN FINKEL
The basis of molecular strategies for treating coronary restenosis after angioplasty.
Journal of the American College of Cardiology 1994;23(6):1278-88.
1994: TOREN FINKEL; J A Theriot; K R Dise; Gordon F Tomaselli; Pascal J Goldschmidt-Clermont
Dynamic actin structures stabilized by profilin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1510-4.
1993: R J Guzman; Patricia Lemarchand; Helen-Ann Brown Epstein; Stephen E Epstein; TOREN FINKEL
Efficient and selective adenovirus-mediated gene transfer into vascular neointima.
Circulation 1993;88(6):2838-48.
1993: R J Guzman; Patricia Lemarchand; Helen-Ann Brown Epstein; Stephen E Epstein; TOREN FINKEL
Efficient gene transfer into myocardium by direct injection of adenovirus vectors.
Circulation research 1993;73(6):1202-7.
1993: Stephen E Epstein; E Speir; TOREN FINKEL
Do antisense approaches to the problem of restenosis make sense?
Circulation 1993;88(3):1351-3.
1993: TOREN FINKEL; J Duc; Eric R Fearon; Chi Dang; Gordon F Tomaselli
Detection and modulation in vivo of helix-loop-helix protein-protein interactions.
The Journal of biological chemistry 1993;268(1):5-8.
1992: Eric R Fearon; TOREN FINKEL; Maura L Gillison; S P Kennedy; James F Casella; Gordon F Tomaselli; Jon S Morrow; Chi Dang
Karyoplasmic interaction selection strategy: a general strategy to detect protein-protein interactions in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):7958-62.
1991: A Carbone; R Harbeck; A Dallas; D Nemazee; TOREN FINKEL; R O'Brien; R Kubo; Willi K Born
Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies.
Immunological reviews 1991;120():35-50.
1986: W P Carney; D Petit; P Hamer; Channing J Der; TOREN FINKEL; G M Cooper; M Lefebvre; H Mobtaker; R Delellis; A S Tischler
Monoclonal antibody specific for an activated RAS protein.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7485-9.
1986: Channing J Der; TOREN FINKEL; G M Cooper
Biological and biochemical properties of human rasH genes mutated at codon 61.
Cell 1986;44(1):167-76.
1984: TOREN FINKEL; Channing J Der; G M Cooper
Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21.
Cell 1984;37(1):151-8.
1984: TOREN FINKEL; G M Cooper
Detection of a molecular complex between ras proteins and transferrin receptor.
Cell 1984;36(4):1115-21.