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TAKANARI INOUE

Research Profile

Chemicals & Drugs

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Mouse

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Protein Multimerization

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Publications

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Vedangi Sample; TAKANARI INOUE; Sohum Mehta; QIANG NI; Jin Zhang
Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch.
A Kumazawa; Katsuhiko Mikoshiba; N Mita; T Adachi; M Hirasawa; TAKANARI INOUE; A B Kulkarni; N Shafeghat; H Suzuki; Toshio Ohshima
Cyclin-dependent kinase 5 is required for normal cerebellar development.
Benjamin Lin; Tasuku Ueno; C Joanne Wang; Leah Edelstein-keshet; Andrew Harwell; William R Holmes; TAKANARI INOUE; Andre Levchenko
Synthetic spatially graded Rac activation drives cell polarization and movement.

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All Publications

2013: Vedangi Sample; TAKANARI INOUE; Sohum Mehta; QIANG NI; Jin Zhang
Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch.
ACS chemical biology 2013;8(1):116-21.
2013: A Kumazawa; Katsuhiko Mikoshiba; N Mita; T Adachi; M Hirasawa; TAKANARI INOUE; A B Kulkarni; N Shafeghat; H Suzuki; Toshio Ohshima
Cyclin-dependent kinase 5 is required for normal cerebellar development.
Molecular and cellular neurosciences 2013;52():97-105.
2012: Benjamin Lin; Tasuku Ueno; C Joanne Wang; Leah Edelstein-keshet; Andrew Harwell; William R Holmes; TAKANARI INOUE; Andre Levchenko
Synthetic spatially graded Rac activation drives cell polarization and movement.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):E3668-77.
2012: Siew Cheng Phua; Christopher Pohlmeyer; TAKANARI INOUE
Rapidly relocating molecules between organelles to manipulate small GTPase activity.
ACS chemical biology 2012;7(12):1950-5.
2012: Takafumi Miyamoto; Chandrani Mukherjee; Allison Suarez; Tai-ping Sun; Tasuku Ueno; Michael J Wolfgang; Melinda Chen; Robert DeRose; DAVID MEYERS; TAKANARI INOUE
Rapid and orthogonal logic gating with a gibberellin-induced dimerization system.
Nature chemical biology 2012;8(5):465-70.
2012: Robert DeRose; Scot C Kuo; Tetsuo Nagano; Christopher Pohlmeyer; Tasuku Ueno; Nobuhiro Umeda; TAKANARI INOUE
Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells.
Journal of visualized experiments : JoVE 2012;(61):.
2011: Toru Komatsu; Kai Johnsson; Hiroyuki Okuno; Haruhiko Bito; TAKANARI INOUE; Tetsuo Nagano; Yasuteru Urano
Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling method.
Journal of the American Chemical Society 2011;133(17):6745-51.
2011: Nobuhiro Umeda; Tasuku Ueno; Christopher Pohlmeyer; Tetsuo Nagano; TAKANARI INOUE
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity.
Journal of the American Chemical Society 2011;133(1):12-4.
2011: Tasuku Ueno; Björn H Falkenburger; Christopher Pohlmeyer; TAKANARI INOUE
Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganization.
Science signaling 2011;4(203):ra87.
2010: Toru Komatsu; Igor Kukelyansky; J Michael McCaffery; Tasuku Ueno; Lidenys C Varela; TAKANARI INOUE
Organelle-specific, rapid induction of molecular activities and membrane tethering.
Nature methods 2010;7(3):206-8.
2009: Meghdad Rahdar; TAKANARI INOUE; Tobias Meyer; Jin Zhang; Francisca Vazquez; Peter N Devreotes
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):480-5.
2008: Namiko Abe; TAKANARI INOUE; Thierry Galvez; Lawrence Klein; Tobias Meyer
Dissecting the role of PtdIns(4,5)P2 in endocytosis and recycling of the transferrin receptor.
Journal of cell science 2008;121(Pt 9):1488-94.
2008: Takatoshi Yogo; Yasuteru Urano; Akiko Mizushima; Hisato Sunahara; TAKANARI INOUE; Kenzo Hirose; Masamitsu Iino; Kazuya Kikuchi; Tetsuo Nagano
Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):28-32.
2008: Marc Fivaz; Samuel Bandara; TAKANARI INOUE; Tobias Meyer
Robust neuronal symmetry breaking by Ras-triggered local positive feedback.
Current biology : CB 2008;18(1):44-50.
2008: TAKANARI INOUE; Tobias Meyer
Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration.
PloS one 2008;3(8):e3068.
2007: Kazuhiro Aoki; Takeshi Nakamura; TAKANARI INOUE; Tobias Meyer; Michiyuki Matsuda
An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.
The Journal of cell biology 2007;177(5):817-27.
2007: Jen Liou; Marc Fivaz; TAKANARI INOUE; Tobias Meyer
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9301-6.
2006: Won Do Heo; TAKANARI INOUE; Wei Sun Park; Man Lyang Kim; Byung Ouk Park; Thomas J Wandless; Tobias Meyer
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane.
Science (New York, N.Y.) 2006;314(5804):1458-61.
2006: Byung-Chang Suh; TAKANARI INOUE; Tobias Meyer; Bertil Hille
Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels.
Science (New York, N.Y.) 2006;314(5804):1454-7.
2005: TAKANARI INOUE; Won Do Heo; Joshua S Grimley; Thomas J Wandless; Tobias Meyer
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways.
Nature methods 2005;2(6):415-8.
2004: Takatoshi Yogo; Kazuya Kikuchi; TAKANARI INOUE; Kenzo Hirose; Masamitsu Iino; Tetsuo Nagano
Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.
Chemistry & biology 2004;11(8):1053-8.
2003: TAKANARI INOUE; Kazuya Kikuchi; Kenzo Hirose; Masamitsu Iino; Tetsuo Nagano
Spatiotemporal laser inactivation of inositol 1,4,5-trisphosphate receptors using synthetic small-molecule probes.
Chemistry & biology 2003;10(6):503-9.
2002: Waka Nakanishi; Kazuya Kikuchi; TAKANARI INOUE; Kenzo Hirose; Masamitsu Iino; Tetsuo Nagano
Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor binding.
Bioorganic & medicinal chemistry letters 2002;12(6):911-3.
2001: TAKANARI INOUE; Kazuya Kikuchi; Kenzo Hirose; Masamitsu Iino; Tetsuo Nagano
Small molecule-based laser inactivation of inositol 1,4,5-trisphosphate receptor.
Chemistry & biology 2001;8(1):9-15.
1999: TAKANARI INOUE; Kazuya Kikuchi; Kenzo Hirose; Masamitsu Iino; Tetsuo Nagano
Synthesis and evaluation of 1-position-modified inositol 1,4,5-trisphosphate analogs.
Bioorganic & medicinal chemistry letters 1999;9(12):1697-702.
1998: Katsuhiko Mikoshiba; Teiichi Furuichi; Takayuki Michikawa; Miki Yamamoto-Hino; C Hirashima; H Mizuno; TAKANARI INOUE; Tsuyoshi Uchiyama
[IP3 receptor].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(12 Suppl):1596-602.
1998: TAKANARI INOUE; Kanefusa Kato; K Kohda; Katsuhiko Mikoshiba
Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5366-73.
1997: Shoen Kume; A Yamamoto; TAKANARI INOUE; Akihiko Muto; Hideyuki Okano; Katsuhiko Mikoshiba
Developmental expression of the inositol 1,4,5-trisphosphate receptor and structural changes in the endoplasmic reticulum during oogenesis and meiotic maturation of Xenopus laevis.
Developmental biology 1997;182(2):228-39.
1996: M Matsumoto; T Nakagawa; TAKANARI INOUE; E Nagata; K Tanaka; H Takano; Osamu Minowa; Junko Kuno; S Sakakibara; Maki K Yamada; H Yoneshima; Atsushi Miyawaki; Y Fukuuchi; Teiichi Furuichi; Hideyuki Okano; K Mikoshiba; T Noda
Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.
Nature 1996;379(6561):168-71.
1995: K Kohda; TAKANARI INOUE; K Mikoshiba
Ca2+ release from Ca2+ stores, particularly from ryanodine-sensitive Ca2+ stores, is required for the induction of LTD in cultured cerebellar Purkinje cells.
Journal of neurophysiology 1995;74(5):2184-8.