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Miral Dizdaroglu

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Prasad T Reddy; Gamze Tuna; Pawel Jaruga; Guldal KIRKALI; Bryant C Nelson; Miral Dizdaroglu
Identification and quantification of human DNA repair protein NEIL1 by liquid chromatography/isotope-dilution tandem mass spectrometry.
Elijah J Petersen; Xiaomin Tu; Ming Zheng; Miral Dizdaroglu; Bryant C Nelson
Protective roles of single-wall carbon nanotubes in ultrasonication-induced DNA base damage.
Miral Dizdaroglu
Oxidatively induced DNA damage: mechanisms, repair and disease.

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All Publications

2013: Prasad T Reddy; Gamze Tuna; Pawel Jaruga; Guldal KIRKALI; Bryant C Nelson; Miral Dizdaroglu
Identification and quantification of human DNA repair protein NEIL1 by liquid chromatography/isotope-dilution tandem mass spectrometry.
Journal of proteome research 2013;12(2):1049-61.
2013: Elijah J Petersen; Xiaomin Tu; Ming Zheng; Miral Dizdaroglu; Bryant C Nelson
Protective roles of single-wall carbon nanotubes in ultrasonication-induced DNA base damage.
Small (Weinheim an der Bergstrasse, Germany) 2013;9(2):205-8.
2012: Miral Dizdaroglu
Oxidatively induced DNA damage: mechanisms, repair and disease.
Cancer letters 2012;327(1-2):26-47.
2012: Stéphanie Duclos; Pawel Jaruga; Susan S Wallace; Pierre Aller; Miral Dizdaroglu; Sylvie Doublié
Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine.
DNA repair 2012;11(9):714-25.
2012: Mikiei Tanaka; Miral Dizdaroglu; Pawel Jaruga; Pascal A Küpfer; Christian J Leumann; William E Sonntag; P Boon Chock
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.
Free radical biology & medicine 2012;53(4):854-62.
2012: Miral Dizdaroglu; Pawel Jaruga
Mechanisms of free radical-induced damage to DNA.
Free radical research 2012;46(4):382-419.
2012: Pawel Jaruga; Arkadiusz Jawien; Arkadiusz Migdalski; Ryszard Olinski; Rafal Rozalski; Miral Dizdaroglu
DNA damage products (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines as potential biomarkers in human urine for atherosclerosis.
Biochemistry 2012;51(9):1822-4.
2012: Donald H Atha; Danielle Cleveland; Miral Dizdaroglu; R David Holbrook; Pawel Jaruga; Elijah J Petersen; Huanhua Wang; Baoshan Xing; Bryant C Nelson
Copper oxide nanoparticle mediated DNA damage in terrestrial plant models.
Environmental science & technology 2012;46(3):1819-27.
2011: Guldal KIRKALI; Prasad T Reddy; Cem Terzi; Aras Emre Canda; Miral Dizdaroglu; Pawel Jaruga; Didem Keles; Gulgun OKTAY
Evidence for upregulated repair of oxidatively induced DNA damage in human colorectal cancer.
DNA repair 2011;10(11):1114-20.
2011: Miral Dizdaroglu; Prasad T Reddy; Pawel Jaruga
Identification and quantification of DNA repair proteins by liquid chromatography/isotope-dilution tandem mass spectrometry using their fully 15N-labeled analogues as internal standards.
Journal of proteome research 2011;10(8):3802-13.
2011: Prasad T Reddy; Pawel Jaruga; Bryant C Nelson; Mark Lowenthal; Miral Dizdaroglu
Stable isotope-labeling of DNA repair proteins, and their purification and characterization.
Protein expression and purification 2011;78(1):94-101.
2011: Courtney K Robinson; Kim Webb; Amardeep Kaur; Pawel Jaruga; Miral Dizdaroglu; Nitin S Baliga; Allen Place; Jocelyne DiRuggiero
A major role for nonenzymatic antioxidant processes in the radioresistance of Halobacterium salinarum.
Journal of bacteriology 2011;193(7):1653-62.
2010: Pawel Jaruga; Miral Dizdaroglu
Identification and quantification of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines in human urine as putative biomarkers of oxidatively induced damage to DNA.
Biochemical and biophysical research communications 2010;397(1):48-52.
2010: Minmin Liu; Viswanath Bandaru; Jeffrey P Bond; Pawel Jaruga; Xiaobei Zhao; Plamen P Christov; Cynthia J Burrows; Carmelo J Rizzo; Miral Dizdaroglu; Susan S Wallace
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):4925-30.
2010: Pawel Jaruga; Yan Xiao; Vladimir Vartanian; R Stephen Lloyd; Miral Dizdaroglu
Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines.
Biochemistry 2010;49(6):1053-5.
2010: Yin Guo; Viswanath Bandaru; Pawel Jaruga; Xiaobei Zhao; Cynthia J Burrows; Shigenori Iwai; Miral Dizdaroglu; Jeffrey P Bond; Susan S Wallace
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts.
DNA repair 2010;9(2):177-90.
2009: Pawel Jaruga; Yan Xiao; Bryant C Nelson; Miral Dizdaroglu
Measurement of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines in DNA in vivo by liquid chromatography/isotope-dilution tandem mass spectrometry.
Biochemical and biophysical research communications 2009;386(4):656-60.
2009: Viktoriya S Sidorenko; Arthur P Grollman; Pawel Jaruga; Miral Dizdaroglu; Dmitry O Zharkov
Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.
The FEBS journal 2009;276(18):5149-62.
2009: Michael K Chan; Maria T Ocampo-Hafalla; Vladimir Vartanian; Pawel Jaruga; Guldal KIRKALI; Karen L Koenig; Stuart Brown; R Stephen Lloyd; Miral Dizdaroglu; George W Teebor
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.
DNA repair 2009;8(7):786-94.
2009: Goksel Gokce; Gonen Ozsarlak-Sozer; Gulgun OKTAY; Guldal KIRKALI; Pawel Jaruga; Miral Dizdaroglu; Zeliha Kerry
Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo.
Biochemistry 2009;48(22):4980-7.
2009: Scott D Kathe; Ramiro Barrantes-Reynolds; Pawel Jaruga; Michael R Newton; Cynthia J Burrows; Viswanath Bandaru; Miral Dizdaroglu; Jeffrey P Bond; Susan S Wallace
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.
DNA repair 2009;8(5):643-53.
2009: Meltem Muftuoglu; Nadja C de Souza-Pinto; Arin Dogan; Maria Aamann; Tinna Stevnsner; Ivana Rybanska; Guldal KIRKALI; Miral Dizdaroglu; Vilhelm A Bohr
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase.
The Journal of biological chemistry 2009;284(14):9270-9.
2009: Guldal KIRKALI; Nadja C de Souza-Pinto; Pawel Jaruga; Vilhelm A Bohr; Miral Dizdaroglu
Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice.
DNA repair 2009;8(2):274-8.
2008: Pawel Jaruga; Guldal KIRKALI; Miral Dizdaroglu
Measurement of formamidopyrimidines in DNA.
Free radical biology & medicine 2008;45(12):1601-9.
2008: Miral Dizdaroglu; Guldal KIRKALI; Pawel Jaruga
Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects.
Free radical biology & medicine 2008;45(12):1610-21.
2008: Pawel Jaruga; Miral Dizdaroglu
8,5'-Cyclopurine-2'-deoxynucleosides in DNA: mechanisms of formation, measurement, repair and biological effects.
DNA repair 2008;7(9):1413-25.
2008: Guldal KIRKALI; Mehmet Tunca; Sermin Genc; Pawel Jaruga; Miral Dizdaroglu
Oxidative DNA damage in polymorphonuclear leukocytes of patients with familial Mediterranean fever.
Free radical biology & medicine 2008;44(3):386-93.
2007: Jacob A Theruvathu; Pawel Jaruga; Miral Dizdaroglu; Philip J Brooks
The oxidatively induced DNA lesions 8,5'-cyclo-2'-deoxyadenosine and 8-hydroxy-2'-deoxyadenosine are strongly resistant to acid-induced hydrolysis of the glycosidic bond.
Mechanisms of ageing and development 2007;128(9):494-502.
2007: Mariarosaria D'Errico; Eleonora Parlanti; Massimo Teson; Paolo Degan; T Lemma; Angelo Calcagnile; IVANO IAVARONE; Pawel Jaruga; Monica Ropolo; Antonia M Pedrini; Donata Orioli; Guido Frosina; Giovanna Zambruno; Miral Dizdaroglu; Miria Stefanini; Eugenia Dogliotti
The role of CSA in the response to oxidative DNA damage in human cells.
Oncogene 2007;26(30):4336-43.
2007: Simon G Nyaga; Pawel Jaruga; Althaf Lohani; Miral Dizdaroglu; Michele K Evans
Accumulation of oxidatively induced DNA damage in human breast cancer cell lines following treatment with hydrogen peroxide.
Cell cycle (Georgetown, Tex.) 2007;6(12):1472-8.
2007: Laura Roy; Pawel Jaruga; Thomas G Wood; Amanda K McCullough; Miral Dizdaroglu; R Stephen Lloyd
Human polymorphic variants of the NEIL1 DNA glycosylase.
The Journal of biological chemistry 2007;282(21):15790-8.
2007: Henry Rodriguez; Pawel Jaruga; Dennis Leber; Simon G Nyaga; Michele K Evans; Miral Dizdaroglu
Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of 8,5'-Cyclopurine-2'-deoxynucleosides and 8-hydroxy-2'-deoxyguanosine.
Biochemistry 2007;46(9):2488-96.
2006: Kamal Datta; Pawel Jaruga; Miral Dizdaroglu; Ronald D Neumann; Thomas A Winters
Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.
Radiation research 2006;166(5):767-81.
2006: Mariarosaria D'Errico; Eleonora Parlanti; Massimo Teson; Bruno M Bernardes de Jesus; Paolo Degan; Angelo Calcagnile; Pawel Jaruga; Magnar Bjørås; Marco Crescenzi; Antonia M Pedrini; Jean-Marc Egly; Giovanna Zambruno; Miria Stefanini; Miral Dizdaroglu; Eugenia Dogliotti
New functions of XPC in the protection of human skin cells from oxidative damage.
The EMBO journal 2006;25(18):4305-15.
2006: Donald C Malins; Katie M Anderson; Pawel Jaruga; Callie R Ramsey; Naomi K Gilman; Virginia M Green; Steven W Rostad; Joanne T Emerman; Miral Dizdaroglu
Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer.
Cell cycle (Georgetown, Tex.) 2006;5(15):1629-32.
2006: Katie M Anderson; Pawel Jaruga; Callie R Ramsey; Naomi K Gilman; Virginia M Green; Steven W Rostad; Joanne T Emerman; Miral Dizdaroglu; Donald C Malins
Structural alterations in breast stromal and epithelial DNA: the influence of 8,5'-cyclo-2'-deoxyadenosine.
Cell cycle (Georgetown, Tex.) 2006;5(11):1240-4.
2006: Donald C Malins; Katie M Anderson; John J Stegeman; Pawel Jaruga; Virginia M Green; Naomi K Gilman; Miral Dizdaroglu
Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound.
Environmental health perspectives 2006;114(6):823-9.
2006: Simon G Nyaga; Althaf Lohani; Pawel Jaruga; Andrzej R Trzeciak; Miral Dizdaroglu; Michele K Evans
Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937.
BMC cancer 2006;6():297.
2006: Lauren Seiple; Pawel Jaruga; Miral Dizdaroglu; James T Stivers
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast.
Nucleic acids research 2006;34(1):140-51.
2005: Miral Dizdaroglu
Base-excision repair of oxidative DNA damage by DNA glycosylases.
Mutation research 2005;591(1-2):45-59.
2005: Jingping Hu; Nadja C de Souza-Pinto; Kazuhiro Haraguchi; Barbara A Hogue; Pawel Jaruga; Marc M Greenberg; Miral Dizdaroglu; Vilhelm A Bohr
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes.
The Journal of biological chemistry 2005;280(49):40544-51.
2005: Rachel A Egler; Elaine Fernandes; Kristi Rothermund; Susan M Sereika; Nadja C de Souza-Pinto; Pawel Jaruga; Miral Dizdaroglu; Edward V Prochownik
Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1.
Oncogene 2005;24(54):8038-50.
2005: Elizabeth Mambo; Aditi Chatterjee; Nadja C de Souza-Pinto; Sabine Mayard; Barbara A Hogue; Mohammad Hoque; Miral Dizdaroglu; Vilhelm A Bohr; David Sidransky
Oxidized guanine lesions and hOgg1 activity in lung cancer.
Oncogene 2005;24(28):4496-508.
2005: Jacob A Theruvathu; Pawel Jaruga; Raghu G Nath; Miral Dizdaroglu; Philip J Brooks
Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde.
Nucleic acids research 2005;33(11):3513-20.
2004: Pawel Jaruga; Mustafa Birincioglu; Thomas A Rosenquist; Miral Dizdaroglu
Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA.
Biochemistry 2004;43(50):15909-14.
2004: Henry Rodriguez; Catherine O'Connell; Peter Barker; Donald H Atha; Pawel Jaruga; Mustafa Birincioglu; Michael Marino; Patricia McAndrew; Miral Dizdaroglu
Measurement of DNA biomarkers for the safety of tissue-engineered medical products, using artificial skin as a model.
Tissue engineering 2004;10(9-10):1332-45.
2004: Mark D Evans; Miral Dizdaroglu; Marcus Cooke
Oxidative DNA damage and disease: induction, repair and significance.
Mutation research 2004;567(1):1-61.
2004: Andrzej R Trzeciak; Simon G Nyaga; Pawel Jaruga; Althaf Lohani; Miral Dizdaroglu; Michele K Evans
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
Carcinogenesis 2004;25(8):1359-70.
2004: Prasad Reddy; Pawel Jaruga; Tim O'Connor; Henry Rodriguez; Miral Dizdaroglu
Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase.
Protein expression and purification 2004;34(1):126-33.
2004: Pawel Jaruga; Jacob A Theruvathu; Miral Dizdaroglu; Philip J Brooks
Complete release of (5'S)-8,5'-cyclo-2'-deoxyadenosine from dinucleotides, oligodeoxynucleotides and DNA, and direct comparison of its levels in cellular DNA with other oxidatively induced DNA lesions.
Nucleic acids research 2004;32(11):e87.
2003: Miral Dizdaroglu
Substrate specificities and excision kinetics of DNA glycosylases involved in base-excision repair of oxidative DNA damage.
Mutation research 2003;531(1-2):109-26.
2003: Mustafa Birincioglu; Pawel Jaruga; Goutam Chowdhury; Henry Rodriguez; Miral Dizdaroglu; Kent S Gates
DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
Journal of the American Chemical Society 2003;125(38):11607-15.
2003: Marcus Cooke; Mark D Evans; Miral Dizdaroglu; Joseph Lunec
Oxidative DNA damage: mechanisms, mutation, and disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(10):1195-214.
2003: Richard A Manderville; M Wade Calcutt; Jian Dai; Gyungse Park; Ivan G Gillman; Ronald E Noftle; Abdul K Mohammed; Mustafa Birincioglu; Miral Dizdaroglu; Henry Rodriguez; Steven A Akman
Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A.
Journal of inorganic biochemistry 2003;95(2-3):87-96.
2003: Jingsheng Tuo; Pawel Jaruga; Henry Rodriguez; Vilhelm A Bohr; Miral Dizdaroglu
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):668-74.
2003: Teresa Morales-Ruiz; Mustafa Birincioglu; Pawel Jaruga; Henry Rodriguez; Teresa Roldan-Arjona; Miral Dizdaroglu
Arabidopsis thaliana Ogg1 protein excises 8-hydroxyguanine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from oxidatively damaged DNA containing multiple lesions.
Biochemistry 2003;42(10):3089-95.
2002: Jingsheng Tuo; Pawel Jaruga; Henry Rodriguez; Miral Dizdaroglu; Vilhelm A Bohr
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA.
The Journal of biological chemistry 2002;277(34):30832-7.
2002: Miral Dizdaroglu; Pawel Jaruga; Mustafa Birincioglu; Henry Rodriguez
Free radical-induced damage to DNA: mechanisms and measurement.
Free radical biology & medicine 2002;32(11):1102-15.
2002: Tapas K Hazra; Tadahide Izumi; Istvan Boldogh; Barry Imhoff; Yoke W Kow; Pawel Jaruga; Miral Dizdaroglu; Sankar Mitra
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3523-8.
2002: Pawel Jaruga; Mustafa Birincioglu; Henry Rodriguez; Miral Dizdaroglu
Mass spectrometric assays for the tandem lesion 8,5'-cyclo-2'-deoxyguanosine in mammalian DNA.
Biochemistry 2002;41(11):3703-11.
2002: Pawel Jaruga; Ritche Jabil; Amanda K McCullough; Henry Rodriguez; Miral Dizdaroglu; R Stephen Lloyd
Chlorella virus pyrimidine dimer glycosylase excises ultraviolet radiation- and hydroxyl radical-induced products 4,6-diamino-5-formamidopyrimidine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from DNA.
Photochemistry and photobiology 2002;75(2):85-91.
2002: Sarah Burgess; Pawel Jaruga; ML Dodson; Miral Dizdaroglu; R Stephen Lloyd
Determination of active site residues in Escherichia coli endonuclease VIII.
The Journal of biological chemistry 2002;277(4):2938-44.
2001: Jingsheng Tuo; M Müftüoglu; C Chen; Pawel Jaruga; Rebecca R Selzer; Robert M Brosh; Henry Rodriguez; Miral Dizdaroglu; Vilhelm A Bohr
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA.
The Journal of biological chemistry 2001;276(49):45772-9.
2001: Miral Dizdaroglu; S M Burgess; Pawel Jaruga; Tapas K Hazra; Henry Rodriguez; R Stephen Lloyd
Substrate specificity and excision kinetics of Escherichia coli endonuclease VIII (Nei) for modified bases in DNA damaged by free radicals.
Biochemistry 2001;40(40):12150-6.
2001: Pawel Jaruga; Henry Rodriguez; Miral Dizdaroglu
Measurement of 8-hydroxy-2'-deoxyadenosine in DNA by liquid chromatography/mass spectrometry.
Free radical biology & medicine 2001;31(3):336-44.
2001: Miral Dizdaroglu; Pawel Jaruga; Henry Rodriguez
Identification and quantification of 8,5'-cyclo-2'-deoxy-adenosine in DNA by liquid chromatography/ mass spectrometry.
Free radical biology & medicine 2001;30(7):774-84.
2001: Miral Dizdaroglu; Pawel Jaruga; Henry Rodriguez
Measurement of 8-hydroxy-2'-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry.
Nucleic acids research 2001;29(3):E12.
2001: Marc Audebert; Céline Levalois; Sylvie Chevillard; Miral Dizdaroglu; Serge Boiteux; J Pablo Radicella
hOGG1 gene alterations in human clear cell carcinomas of the kidney: effect of single mutations in hOGG1 gene on substrate specificity of the hOGG1 protein.
Advances in experimental medicine and biology 2001;500():617-20.
2000: Claudine Dherin; Miral Dizdaroglu; H Doerflinger; Serge Boiteux; J Pablo Radicella
Repair of oxidative DNA damage in Drosophila melanogaster: identification and characterization of dOgg1, a second DNA glycosylase activity for 8-hydroxyguanine and formamidopyrimidines.
Nucleic acids research 2000;28(23):4583-92.
2000: Tapas K Hazra; Tadahide Izumi; R Venkataraman; Yoke W Kow; Miral Dizdaroglu; Sankar Mitra
Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII.
The Journal of biological chemistry 2000;275(36):27762-7.
2000: Henry Rodriguez; Juan Jurado; Jacques Laval; Miral Dizdaroglu
Comparison of the levels of 8-hydroxyguanine in DNA as measured by gas chromatography mass spectrometry following hydrolysis of DNA by Escherichia coli Fpg protein or formic acid.
Nucleic acids research 2000;28(15):E75.
2000: Marc Audebert; J Pablo Radicella; Miral Dizdaroglu
Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein.
Nucleic acids research 2000;28(14):2672-8.
2000: Wojciech Bal; R Liang; J Lukszo; S H Lee; Miral Dizdaroglu; Kazimierz S Kasprzak
Ni(II) specifically cleaves the C-terminal tail of the major variant of histone H2A and forms an oxidative damage-mediating complex with the cleaved-off octapeptide.
Chemical research in toxicology 2000;13(7):616-24.
2000: A Gogos; Derek Jantz; S Sentürker; D Richardson; Miral Dizdaroglu; Neil D Clarke
Assignment of enzyme substrate specificity by principal component analysis of aligned protein sequences: an experimental test using DNA glycosylase homologs.
Proteins 2000;40(1):98-105.
2000: Miral Dizdaroglu; Cecile Bauche; Henry Rodriguez; Jacques Laval
Novel substrates of Escherichia coli nth protein and its kinetics for excision of modified bases from DNA damaged by free radicals.
Biochemistry 2000;39(18):5586-92.
1999: Claudine Dherin; J Pablo Radicella; Miral Dizdaroglu; Serge Boiteux
Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations.
Nucleic acids research 1999;27(20):4001-7.
1999: Ho Jin You; RL Swanson; C Harrington; Anita H Corbett; Sue Jinks-Robertson; S Sentürker; S S Wallace; Serge Boiteux; Miral Dizdaroglu; Paul W. Doetsch
Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.
Biochemistry 1999;38(35):11298-306.
1999: Robert Michael Anson; S Sentürker; Miral Dizdaroglu; Vilhelm A Bohr
Measurement of oxidatively induced base lesions in liver from Wistar rats of different ages.
Free radical biology & medicine 1999;27(3-4):456-62.
1999: S Sentürker; Miral Dizdaroglu
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not?
Free radical biology & medicine 1999;27(3-4):370-80.
1999: LJ Lipinski; N Hoehr; SJ Mazur; Grigory L Dianov; S Sentürker; Miral Dizdaroglu; Vilhelm A Bohr
Repair of oxidative DNA base lesions induced by fluorescent light is defective in xeroderma pigmentosum group A cells.
Nucleic acids research 1999;27(15):3153-8.
1999: S Sentürker; Cecile Bauche; Jacques Laval; Miral Dizdaroglu
Substrate specificity of Deinococcus radiodurans Fpg protein.
Biochemistry 1999;38(29):9435-9.
1999: R Liang; S Senturker; X Shi; Wojciech Bal; Miral Dizdaroglu; Kazimierz S Kasprzak
Effects of Ni(II) and Cu(II) on DNA interaction with the N-terminal sequence of human protamine P2: enhancement of binding and mediation of oxidative DNA strand scission and base damage.
Carcinogenesis 1999;20(5):893-8.
1999: Simon Melov; Pinar E Coskun; M Patel; R Tuinstra; BA Cottrell; Albert S Jun; TH Zastawny; Miral Dizdaroglu; S I Goodman; T T Huang; H Miziorko; C J Epstein; Douglas C Wallace
Mitochondrial disease in superoxide dismutase 2 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):846-51.
1999: Miral Dizdaroglu; B Karahalil; S Sentürker; T J Buckley; T Roldán-Arjona
Excision of products of oxidative DNA base damage by human NTH1 protein.
Biochemistry 1999;38(1):243-6.
1998: Miral Dizdaroglu
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.
Free radical research 1998;29(6):551-63.
1998: S Sentürker; Patricia Auffret van Der Kemp; Ho Jin You; Paul W. Doetsch; Miral Dizdaroglu; Serge Boiteux
Substrate specificities of the ntg1 and ntg2 proteins of Saccharomyces cerevisiae for oxidized DNA bases are not identical.
Nucleic acids research 1998;26(23):5270-6.
1998: B Karahalil; P M Girard; Serge Boiteux; Miral Dizdaroglu
Substrate specificity of the Ogg1 protein of Saccharomyces cerevisiae: excision of guanine lesions produced in DNA by ionizing radiation- or hydrogen peroxide/metal ion-generated free radicals.
Nucleic acids research 1998;26(5):1228-33.
1998: B Karahalil; T Roldán-Arjona; Miral Dizdaroglu
Substrate specificity of Schizosaccharomyces pombe Nth protein for products of oxidative DNA damage.
Biochemistry 1998;37(2):590-5.
1997: Walter A Deutsch; A Yacoub; Pawel Jaruga; TH Zastawny; Miral Dizdaroglu
Characterization and mechanism of action of Drosophila ribosomal protein S3 DNA glycosylase activity for the removal of oxidatively damaged DNA bases.
The Journal of biological chemistry 1997;272(52):32857-60.
1997: S Sentürker; B Karahalil; M Inal; H Yilmaz; H Müslümanoglu; G Gedikoglu; Miral Dizdaroglu
Oxidative DNA base damage and antioxidant enzyme levels in childhood acute lymphoblastic leukemia.
FEBS letters 1997;416(3):286-90.
1997: Kazimierz S Kasprzak; Pawel Jaruga; TH Zastawny; S L North; C W Riggs; Ryszard Olinski; Miral Dizdaroglu
Oxidative DNA base damage and its repair in kidneys and livers of nickel(II)-treated male F344 rats.
Carcinogenesis 1997;18(2):271-7.
1997: A Karakaya; Pawel Jaruga; V A Bohr; A P Grollman; Miral Dizdaroglu
Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein.
Nucleic acids research 1997;25(3):474-9.
1996: Ryszard Olinski; TH Zastawny; Marek Foksinski; W Windorbska; Pawel Jaruga; Miral Dizdaroglu
DNA base damage in lymphocytes of cancer patients undergoing radiation therapy.
Cancer letters 1996;106(2):207-15.
1996: Pawel Jaruga; Miral Dizdaroglu
Repair of products of oxidative DNA base damage in human cells.
Nucleic acids research 1996;24(8):1389-94.
1996: M Höss; Pawel Jaruga; TH Zastawny; Miral Dizdaroglu; S Pääbo
DNA damage and DNA sequence retrieval from ancient tissues.
Nucleic acids research 1996;24(7):1304-7.
1996: Miral Dizdaroglu; A Karakaya; Pawel Jaruga; Geir Slupphaug; Hans E Krokan
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage.
Nucleic acids research 1996;24(3):418-22.
1996: Miral Dizdaroglu; TH Zastawny; J R Carmical; R Stephen Lloyd
A novel DNA N-glycosylase activity of E. coli T4 endonuclease V that excises 4,6-diamino-5-formamidopyrimidine from DNA, a UV-radiation- and hydroxyl radical-induced product of adenine.
Mutation research 1996;362(1):1-8.
1995: S A Altman; TH Zastawny; L Randers-Eichhorn; Marco A Cacciuttolo; S A Akman; Miral Dizdaroglu; Govind Rao
Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions.
Free radical biology & medicine 1995;19(6):897-902.
1995: TH Zastawny; S A Altman; L Randers-Eichhorn; R Madurawe; J A Lumpkin; Miral Dizdaroglu; Govind Rao
DNA base modifications and membrane damage in cultured mammalian cells treated with iron ions.
Free radical biology & medicine 1995;18(6):1013-22.
1995: TH Zastawny; Paul W. Doetsch; Miral Dizdaroglu
A novel activity of E. coli uracil DNA N-glycosylase excision of isodialuric acid (5,6-dihydroxyuracil), a major product of oxidative DNA damage, from DNA.
FEBS letters 1995;364(3):255-8.
1995: Ryszard Olinski; TH Zastawny; Marek Foksinski; A Barecki; Miral Dizdaroglu
DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia.
Free radical biology & medicine 1995;18(4):807-13.
1994: T Mori; Miral Dizdaroglu
Ionizing radiation causes greater DNA base damage in radiation-sensitive mutant M10 cells than in parent mouse lymphoma L5178Y cells.
Radiation research 1994;140(1):85-90.
1994: Kazimierz S Kasprzak; TH Zastawny; S L North; C W Riggs; Bhalchandra A Diwan; Jerry M Rice; Miral Dizdaroglu
Oxidative DNA base damage in renal, hepatic, and pulmonary chromatin of rats after intraperitoneal injection of cobalt(II) acetate.
Chemical research in toxicology 1994;7(3):329-35.
1994: S A Altman; TH Zastawny; L Randers; Z Lin; J A Lumpkin; J Remacle; Miral Dizdaroglu; Govind Rao
tert.-butyl hydroperoxide-mediated DNA base damage in cultured mammalian cells.
Mutation research 1994;306(1):35-44.
1994: Pawel Jaruga; TH Zastawny; J Skokowski; Miral Dizdaroglu; Ryszard Olinski
Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer.
FEBS letters 1994;341(1):59-64.
1994: Miral Dizdaroglu
Chemical determination of oxidative DNA damage by gas chromatography-mass spectrometry.
Methods in enzymology 1994;234():3-16.
1993: T Mori; Y Hori; Miral Dizdaroglu
DNA base damage generated in vivo in hepatic chromatin of mice upon whole body gamma-irradiation.
International journal of radiation biology 1993;64(6):645-50.
1993: Miral Dizdaroglu; J Laval; Serge Boiteux
Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals.
Biochemistry 1993;32(45):12105-11.
1993: Miral Dizdaroglu; Ryszard Olinski; James Doroshow; S A Akman
Modification of DNA bases in chromatin of intact target human cells by activated human polymorphonuclear leukocytes.
Cancer research 1993;53(6):1269-72.
1993: Miral Dizdaroglu
Quantitative determination of oxidative base damage in DNA by stable isotope-dilution mass spectrometry.
FEBS letters 1993;315(1):1-6.
1993: M Misra; R Olinski; Miral Dizdaroglu; Kazimierz S Kasprzak
Enhancement by L-histidine of nickel(II)-induced DNA-protein cross-linking and oxidative DNA base damage in the rat kidney.
Chemical research in toxicology 1993;6(1):33-7.
1992: Kazimierz S Kasprzak; Bhalchandra A Diwan; Jerry M Rice; M Misra; C W Riggs; R Olinski; Miral Dizdaroglu
Nickel(II)-mediated oxidative DNA base damage in renal and hepatic chromatin of pregnant rats and their fetuses. Possible relevance to carcinogenesis.
Chemical research in toxicology 1992;5(6):809-15.
1992: Ryszard Olinski; TH Zastawny; J Budzbon; J Skokowski; W Zegarski; Miral Dizdaroglu
DNA base modifications in chromatin of human cancerous tissues.
FEBS letters 1992;309(2):193-8.
1992: Miral Dizdaroglu
Oxidative damage to DNA in mammalian chromatin.
Mutation research 1992;275(3-6):331-42.
1992: Ryszard Olinski; Z Nackerdien; Miral Dizdaroglu
DNA-protein cross-linking between thymine and tyrosine in chromatin of gamma-irradiated or H2O2-treated cultured human cells.
Archives of biochemistry and biophysics 1992;297(1):139-43.
1992: Miral Dizdaroglu
Measurement of radiation-induced damage to DNA at the molecular level.
International journal of radiation biology 1992;61(2):175-83.
1992: Z Nackerdien; Ryszard Olinski; Miral Dizdaroglu
DNA base damage in chromatin of gamma-irradiated cultured human cells.
Free radical research communications 1992;16(4):259-73.
1991: Z Nackerdien; K S Kasprzak; Govind Rao; Barry Halliwell; Miral Dizdaroglu
Nickel(II)- and cobalt(II)-dependent damage by hydrogen peroxide to the DNA bases in isolated human chromatin.
Cancer research 1991;51(21):5837-42.
1991: Z Nackerdien; Govind Rao; Marco A Cacciuttolo; E Gajewski; Miral Dizdaroglu
Chemical nature of DNA-protein cross-links produced in mammalian chromatin by hydrogen peroxide in the presence of iron or copper ions.
Biochemistry 1991;30(20):4873-9.
1991: E Gajewski; Okezie I Aruoma; Miral Dizdaroglu; Barry Halliwell
Bleomycin-dependent damage to the bases in DNA is a minor side reaction.
Biochemistry 1991;30(9):2444-8.
1991: Miral Dizdaroglu; Z Nackerdien; B C Chao; E Gajewski; Govind Rao
Chemical nature of in vivo DNA base damage in hydrogen peroxide-treated mammalian cells.
Archives of biochemistry and biophysics 1991;285(2):388-90.
1991: Miral Dizdaroglu; Govind Rao; Barry Halliwell; E Gajewski
Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions.
Archives of biochemistry and biophysics 1991;285(2):317-24.
1991: Okezie I Aruoma; Barry Halliwell; E Gajewski; Miral Dizdaroglu
Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide.
The Biochemical journal 1991;273 ( Pt 3)():601-4.
1991: Miral Dizdaroglu
Chemical determination of free radical-induced damage to DNA.
Free radical biology & medicine 1991;10(3-4):225-42.
1990: Miral Dizdaroglu; Okezie I Aruoma; Barry Halliwell
Modification of bases in DNA by copper ion-1,10-phenanthroline complexes.
Biochemistry 1990;29(36):8447-51.
1990: A F Fuciarelli; B J Wegher; William F Blakely; Miral Dizdaroglu
Yields of radiation-induced base products in DNA: effects of DNA conformation and gassing conditions.
International journal of radiation biology 1990;58(3):397-415.
1990: E Gajewski; Govind Rao; Z Nackerdien; Miral Dizdaroglu
Modification of DNA bases in mammalian chromatin by radiation-generated free radicals.
Biochemistry 1990;29(34):7876-82.
1990: William F Blakely; A F Fuciarelli; B J Wegher; Miral Dizdaroglu
Hydrogen peroxide-induced base damage in deoxyribonucleic acid.
Radiation research 1990;121(3):338-43.
1990: E Gajewski; Miral Dizdaroglu
Hydroxyl radical induced cross-linking of cytosine and tyrosine in nucleohistone.
Biochemistry 1990;29(4):977-80.
1989: Okezie I Aruoma; Barry Halliwell; E Gajewski; Miral Dizdaroglu
Damage to the bases in DNA induced by hydrogen peroxide and ferric ion chelates.
The Journal of biological chemistry 1989;264(34):20509-12.
1989: J H Jackson; E Gajewski; Ingrid Schraufstatter; P A Hyslop; A F Fuciarelli; Charles G Cochrane; Miral Dizdaroglu
Damage to the bases in DNA induced by stimulated human neutrophils.
The Journal of clinical investigation 1989;84(5):1644-9.
1989: Okezie I Aruoma; Barry Halliwell; Miral Dizdaroglu
Iron ion-dependent modification of bases in DNA by the superoxide radical-generating system hypoxanthine/xanthine oxidase.
The Journal of biological chemistry 1989;264(22):13024-8.
1989: A F Fuciarelli; B J Wegher; E Gajewski; Miral Dizdaroglu; William F Blakely
Quantitative measurement of radiation-induced base products in DNA using gas chromatography-mass spectrometry.
Radiation research 1989;119(2):219-31.
1989: Miral Dizdaroglu; E Gajewski
Structure and mechanism of hydroxyl radical-induced formation of a DNA-protein cross-link involving thymine and lysine in nucleohistone.
Cancer research 1989;49(13):3463-7.
1989: Miral Dizdaroglu; E Gajewski; P Reddy; S A Margolis
Structure of a hydroxyl radical induced DNA-protein cross-link involving thymine and tyrosine in nucleohistone.
Biochemistry 1989;28(8):3625-8.
1988: E Gajewski; A F Fuciarelli; Miral Dizdaroglu
Structure of hydroxyl radical-induced DNA-protein crosslinks in calf thymus nucleohistone in vitro.
International journal of radiation biology 1988;54(3):445-59.
1988: S A Margolis; B Coxon; E Gajewski; Miral Dizdaroglu
Structure of a hydroxyl radical induced cross-link of thymine and tyrosine.
Biochemistry 1988;27(17):6353-9.
1988: M L Dirksen; W F Blakely; Eric Holwitt; Miral Dizdaroglu
Effect of DNA conformation on the hydroxyl radical-induced formation of 8,5'-cyclopurine 2'-deoxyribonucleoside residues in DNA.
International journal of radiation biology 1988;54(2):195-204.