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Folkert Kuipers

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Anatomy

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Maxi Meissner; Henk Wolters; Rick Havinga; Folkert Kuipers; Vincent Bloks; Renze Boverhof; Rudolf A de Boer; Albert K Groen
Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity.
T H van Dijk; Vincent Bloks; Theo S Boer; Aldo Grefhorst; A K Groen; Folkert Kuipers; A J Laskewitz; D J Reijngoud
A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice.
Ylva Bonde; Folkert Kuipers; Torsten Plösch; Bo Angelin; Mats Rudling
Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.

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2013: Maxi Meissner; Henk Wolters; Rick Havinga; Folkert Kuipers; Vincent Bloks; Renze Boverhof; Rudolf A de Boer; Albert K Groen
Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity.
Atherosclerosis 2013;228(1):117-23.
2013: T H van Dijk; Vincent Bloks; Theo S Boer; Aldo Grefhorst; A K Groen; Folkert Kuipers; A J Laskewitz; D J Reijngoud
A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice.
Laboratory animals 2013;47(2):79-88.
2012: Ylva Bonde; Folkert Kuipers; Torsten Plösch; Bo Angelin; Mats Rudling
Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.
Hepatology (Baltimore, Md.) 2012;56(5):1828-37.
2012: Anke J Laskewitz; Dirk-Jan Reijngoud; Marijke Schreurs; Theo H Van Dijk; Marie-José van Lierop; Vincent Bloks; Wim H Dokter; Aldo Grefhorst; Folkert Kuipers; Albert K Groen
Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance.
Endocrinology 2012;153(8):3713-23.
2012: Carolina Huaman Samanez; Olivier Briand; Sandrine Caron; Véronique Clavey; Hélène Dehondt; Isabelle Duplan; Nathalie Hennuyer; Folkert Kuipers; Bart Staels
The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism.
Archives of physiology and biochemistry 2012;118(3):102-11.
2012: Aldo Grefhorst; Marije Boesjes; Gemma Brufau; Folkert Kuipers; Maaike H Oosterveer; Albert K Groen
Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol.
Atherosclerosis 2012;222(2):382-9.
2012: Jan Freark de Boer; Markus van der Giet; Jelske N van der Veen; Wijtske Annema; Folkert Kuipers; Niels Nijstad; Marijke Schreurs; Uwe J F Tietge
Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice.
Journal of lipid research 2012;53(3):348-57.
2012: Karen van der Weide; Susan de Jonge-Peeters; Elisabeth G E de Vries; Rudolf S N Fehrmann; Gerwin Huls; Folkert Kuipers; Jan Jacob Schuringa; Edo Vellenga
Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.
Experimental hematology 2012;40(3):177-186.e6.
2012: Marie-José C van Lierop; Rene C van Schaik; Wynand Alkema; Annemieke M H Boots; Paolo G M Conti; Jacob de Vlieg; R Dijkema; Aldo Grefhorst; Claudia L Hofstra; Benno A Ingelse; Christan G J M Jans; Folkert Kuipers; Anke J Laskewitz; Scott J Lusher; Ross McGuire; Ralf Plate; Willem G E J Schoonen; Ruben L Smeets; Martin J Smit; Cornelis M Timmers; Constant A A van Boeckel; Hans M van der Maaden; Theo H Van Dijk; Marcel van Duin; Wim H A Dokter
Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.
PloS one 2012;7(11):e48385.
2011: Maxi Meissner; Uwe J F Tietge; Rick Havinga; Folkert Kuipers; Elisa Lombardo; Albert K Groen
Voluntary wheel running increases bile acid as well as cholesterol excretion and decreases atherosclerosis in hypercholesterolemic mice.
Atherosclerosis 2011;218(2):323-9.
2011: Gemma Brufau; Albert K Groen; Folkert Kuipers
Reverse cholesterol transport revisited: contribution of biliary versus intestinal cholesterol excretion.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(8):1726-33.
2011: Janne Prawitt; Johanna H M Stroeve; Theo H Van Dijk; Vidya R Velagapudi; Mouaadh Abdelkarim; Emmanuel Bouchaert; Bertrand Cariou; Sandrine Caron; Mehdi Daoudi; Emilie Dorchies; Helene Duez; Julie Dumont; Frank J Gonzalez; Folkert Kuipers; Sophie Lestavel; Anthony Lucas; Matej Oresic; Iuliana Popescu; Bart Staels
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.
Diabetes 2011;60(7):1861-71.
2011: Tim Vanmierlo; Arjan Blokland; Vincent W Bloks; Jos Dederen; Amanda Kiliaan; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Kris Rutten; Eric J G Sijbrands; Harry Steinbusch; Leonie C van Vark-van der Zee; Monique Mulder
Liver X receptor activation restores memory in aged AD mice without reducing amyloid.
Neurobiology of aging 2011;32(7):1262-72.
2011: Tim Vanmierlo; Arjan Blokland; Vincent Bloks; Silvia Friedrichs; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Frans C Ramaekers; Kris Rutten; Eric Sijbrands; Harry Steinbusch; Leonie C van Vark-van der Zee; Monique Mulder
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
Plant foods for human nutrition (Dordrecht, Netherlands) 2011;66(2):149-56.
2011: Carolien Out; Jurre Hageman; Vincent Bloks; Han Gerrits; Maarten D Sollewijn Gelpke; Trijnie Bos; Rick Havinga; Martin J Smit; Folkert Kuipers; Albert K Groen
Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration.
Hepatology (Baltimore, Md.) 2011;53(6):2075-85.
2011: Sandrine Caron; An Verrijken; Ilse Mertens; Carolina Huaman Samanez; Gisèle Mautino; Joel T Haas; Daniel Duran-Sandoval; Janne Prawitt; Sven Francque; Emmanuelle Vallez; Anne Muhr-Tailleux; Isabelle Berard; Folkert Kuipers; Jan A Kuivenhoven; Sudha B Biddinger; Marja-Riitta Taskinen; Luc Van Gaal; Bart Staels
Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(3):513-9.
2011: Maaike H Oosterveer; Pieter Jj Sauer; Theo H Van Dijk; Aycha Bleeker; Vincent Bloks; Trijnie Bos; Pieter T de Boer; Anniek H Koolman; Folkert Kuipers; Gertjan van Dijk
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function.
Nutrition & metabolism 2011;8():93.
2011: Maxi Meissner; Michael Müller; Dirk-Jan Reijngoud; Theo H Van Dijk; Theo Boer; Albert Gerding; Albert K Groen; Rick Havinga; Hilde Herrema; Folkert Kuipers
Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.
PloS one 2011;6(11):e24564.
2011: Gemma Brufau; Folkert Kuipers; Yuguang Lin; Elke A Trautwein; Albert K Groen
A reappraisal of the mechanism by which plant sterols promote neutral sterol loss in mice.
PloS one 2011;6(6):e21576.
2011: Jimmy F P Berbée; Arjan Blokland; Thomas Gautier; M'hamed Hadfoune; Paula J Jansen; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Frans C S Ramaekers; Patrick C N Rensen; Eric Sijbrands; Tim Vanmierlo; Karlygash Abildayeva; Monique Mulder
Apolipoprotein CI knock-out mice display impaired memory functions.
Journal of Alzheimer's disease : JAD 2011;23(4):737-47.
2010: Aldo Grefhorst; Marijke Schreurs; Maaike H Oosterveer; Víctor Cortés; Rick Havinga; Andreas W Herling; Dirk-Jan Reijngoud; Albert K Groen; Folkert Kuipers
Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.
The Biochemical journal 2010;432(2):249-54.
2010: Mouaadh Abdelkarim; Sandrine Caron; Christian Duhem; Janne Prawitt; Julie Dumont; Anthony Lucas; Emmanuel Bouchaert; Olivier Briand; John Brozek; Folkert Kuipers; Catherine Fievet; Bertrand Cariou; Bart Staels
The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma and interfering with the Wnt/beta-catenin pathways.
The Journal of biological chemistry 2010;285(47):36759-67.
2010: Gemma Brufau; Frans Stellaard; Kris Prado; Vincent W Bloks; Elles Jonkers; Renze Boverhof; Folkert Kuipers; Elizabeth J Murphy
Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism.
Hepatology (Baltimore, Md.) 2010;52(4):1455-64.
2010: Torsten Plösch; A Gellhaus; E M E van Straten; N Wolf; N C A Huijkman; M Schmidt; C E Dunk; Folkert Kuipers; E Winterhager
The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells: a reason for alterations in preeclampsia?
Placenta 2010;31(10):910-8.
2010: Irma Kuipers; Jiang Li; Inge Vreeswijk-Baudoin; Johan Koster; Pim van der Harst; Herman H W Silljé; Folkert Kuipers; Dirk J van Veldhuisen; Wiek H van Gilst; Rudolf A de Boer
Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo.
European journal of heart failure 2010;12(10):1042-50.
2010: Johanna H M Stroeve; Gemma Brufau; Frans Stellaard; Frank J Gonzalez; Bart Staels; Folkert Kuipers
Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice.
Laboratory investigation; a journal of technical methods and pathology 2010;90(10):1457-67.
2010: Maaike H Oosterveer; Aldo Grefhorst; Albert K Groen; Folkert Kuipers
The liver X receptor: control of cellular lipid homeostasis and beyond Implications for drug design.
Progress in lipid research 2010;49(4):343-52.
2010: Frans Stellaard; Vincent W Bloks; Hans G M Burgerhof; Richard A Scheltema; Elizabeth J Murphy; Hans A Romijn; August Smelt; Gemma Brufau; Folkert Kuipers
Two time-point assessment of bile acid kinetics in humans using stable isotopes.
Isotopes in environmental and health studies 2010;46(3):325-36.
2010: Jurre Hageman; Hilde Herrema; Albert K Groen; Folkert Kuipers
A role of the bile salt receptor FXR in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(8):1519-28.
2010: Maxi Meissner; Rick Havinga; Renze Boverhof; Ido Kema; Albert K Groen; Folkert Kuipers
Exercise enhances whole-body cholesterol turnover in mice.
Medicine and science in sports and exercise 2010;42(8):1460-8.
2010: Hester van Meer; Esther M E van Straten; Julius F W Baller; Theo H van Dijk; Torsten Plösch; Folkert Kuipers; Henkjan J Verkade
The effects of intrauterine malnutrition on maternal-fetal cholesterol transport and fetal lipid synthesis in mice.
Pediatric research 2010;68(1):10-5.
2010: Irma Kuipers; Pim van der Harst; Folkert Kuipers; Linda van Genne; Maaike Goris; Jukka Y Lehtonen; Dirk J van Veldhuisen; Wiek H van Gilst; Rudolf A de Boer
Activation of liver X receptor-alpha reduces activation of the renal and cardiac renin-angiotensin-aldosterone system.
Laboratory investigation; a journal of technical methods and pathology 2010;90(4):630-6.
2010: Hilde Herrema; Maxi Meissner; Theo H Van Dijk; Gemma Brufau; Renze Boverhof; Maaike H Oosterveer; Dirk-Jan Reijngoud; Michael Müller; Frans Stellaard; Albert K Groen; Folkert Kuipers
Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptor alpha-controlled metabolic pathways in mice.
Hepatology (Baltimore, Md.) 2010;51(3):806-16.
2010: Harmen Wiersma; Niels Nijstad; Thomas Gautier; Jahangir Iqbal; Folkert Kuipers; M Mahmood Hussain; Uwe J F Tietge
Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice.
Journal of lipid research 2010;51(3):544-53.
2010: Esther M E van Straten; Vincent W Bloks; Nicolette C A Huijkman; Julius F W Baller; Hester van Meer; Dieter Lütjohann; Folkert Kuipers; Torsten Plösch
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;298(2):R275-82.
2010: Gemma Brufau; Matthias J Bahr; Bart Staels; Thierry Claudel; Johann Ockenga; Klaus Hw Böker; Elizabeth J Murphy; Kris Prado; Frans Stellaard; Michael P Manns; Folkert Kuipers; Uwe Jf Tietge
Plasma bile acids are not associated with energy metabolism in humans.
Nutrition & metabolism 2010;7():73.
2010: Maxi Meissner; Niels Nijstad; Folkert Kuipers; Uwe J F Tietge
Voluntary exercise increases cholesterol efflux but not macrophage reverse cholesterol transport in vivo in mice.
Nutrition & metabolism 2010;7():54.
2010: Tim Vanmierlo; Vincent W Bloks; Leonie C van Vark-van der Zee; Kris Rutten; Anja Kerksiek; Silvia Friedrichs; Eric Sijbrands; Harry W Steinbusch; Folkert Kuipers; Dieter Lütjohann; Monique Mulder
Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(1):117-27.
2009: Maaike H Oosterveer; Aldo Grefhorst; Theo H van Dijk; Rick Havinga; Bart Staels; Folkert Kuipers; Albert K Groen; Dirk-Jan Reijngoud
Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice.
The Journal of biological chemistry 2009;284(49):34036-44.
2009: Frans Stellaard; Gemma Brufau; Renze Boverhof; Elles Zwanet Jonkers; Theo Boer; Folkert Kuipers
Developments in bile acid kinetic measurements using (13)C and (2)H: 10(5) times improved sensitivity during the last 40 years.
Isotopes in environmental and health studies 2009;45(4):275-88.
2009: Karim El Harchaoui; Remco Franssen; G Kees Hovingh; Radjesh J Bisoendial; Frans Stellaard; Folkert Kuipers; John J P Kastelein; Jan Albert Kuivenhoven; Erik S G Stroes; Albert K Groen
Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia.
Atherosclerosis 2009;207(2):614-6.
2009: Robert H J Bandsma; Dirk-Jan Reijngoud; G P A Smit; Folkert Kuipers
Adiponectin levels correlate with the severity of hypertriglyceridaemia in glycogen storage disease Ia.
Journal of inherited metabolic disease 2009;32 Suppl 1():S27-31.
2009: Esther M E van Straten; Henkjan J Verkade; Theo H Van Dijk; Hester van Meer; Julius F W Baller; Nicolette C A Huijkman; Folkert Kuipers; Torsten Plösch
Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice.
American journal of physiology. Endocrinology and metabolism 2009;297(5):E1171-8.
2009: Harmen Wiersma; Alberto Gatti; Niels Nijstad; Ronald P J Oude Elferink; Folkert Kuipers; Uwe J F Tietge
Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.
Hepatology (Baltimore, Md.) 2009;50(4):1263-72.
2009: M Schreurs; T H van Dijk; A Gerding; R Havinga; Dirk-Jan Reijngoud; Folkert Kuipers
Soraphen, an inhibitor of the acetyl-CoA carboxylase system, improves peripheral insulin sensitivity in mice fed a high-fat diet.
Diabetes, obesity & metabolism 2009;11(10):987-91.
2009: Carlos Vrins; Astrid E van der Velde; Karin van den Oever; Johannes Levels; Stephane Huet; Ronald P J Oude Elferink; Folkert Kuipers; Albert K Groen
Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux.
Journal of lipid research 2009;50(10):2046-54.
2009: Harmen Wiersma; Niels Nijstad; Jan Freark de Boer; Ruud Out; Wytse Hogewerf; Theo Van berkel; Folkert Kuipers; Uwe J F Tietge
Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet.
Atherosclerosis 2009;206(1):141-7.
2009: Harmen Wiersma; Alberto Gatti; Niels Nijstad; Folkert Kuipers; Uwe J F Tietge
Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice.
Journal of lipid research 2009;50(8):1571-80.
2009: Jelske N van der Veen; Theo H Van Dijk; Carlos L J Vrins; Hester van Meer; Rick Havinga; Klaas Bijsterveld; Uwe J F Tietge; Albert K Groen; Folkert Kuipers
Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.
The Journal of biological chemistry 2009;284(29):19211-9.
2009: Susan D P W M de Jonge-Peeters; Karen van der Weide; Folkert Kuipers; Wim J Sluiter; Elisabeth G E de Vries; Edo Vellenga
Variability in responsiveness to lovastatin of the primitive CD34+ AML subfraction compared to normal CD34+ cells.
Annals of hematology 2009;88(6):573-80.
2009: Karen van der Weide; Susan D P W M de Jonge-Peeters; Folkert Kuipers; Elisabeth G E de Vries; Edo Vellenga
Combining simvastatin with the farnesyltransferase inhibitor tipifarnib results in an enhanced cytotoxic effect in a subset of primary CD34+ acute myeloid leukemia samples.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(9):3076-83.
2009: Cédric Le May; Sanae Kourimate; Cédric Langhi; Maud Chétiveaux; Anne Jarry; Christine Comera; Xavier Collet; Folkert Kuipers; Michel Krempf; Bertrand Cariou; Philippe Costet
Proprotein convertase subtilisin kexin type 9 null mice are protected from postprandial triglyceridemia.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(5):684-90.
2009: Theo H van Dijk; Aldo Grefhorst; Maaike H Oosterveer; Vincent Bloks; Bart Staels; Dirk-Jan Reijngoud; Folkert Kuipers
An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice.
The Journal of biological chemistry 2009;284(16):10315-23.
2009: Eberhard Windler; Birgit-Christiane Zyriax; Folkert Kuipers; Jakob Linseisen; Heiner Boeing
Association of plasma phytosterol concentrations with incident coronary heart disease Data from the CORA study, a case-control study of coronary artery disease in women.
Atherosclerosis 2009;203(1):284-90.
2009: Maaike H Oosterveer; Theo H van Dijk; Uwe J F Tietge; Theo Boer; Rick Havinga; Frans Stellaard; Albert K Groen; Folkert Kuipers; Dirk-Jan Reijngoud
High fat feeding induces hepatic fatty acid elongation in mice.
PloS one 2009;4(6):e6066.
2009: Jaap Mulder; Saul J Karpen; Uwe J F Tietge; Folkert Kuipers
Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.
Frontiers in bioscience : a journal and virtual library 2009;14():2599-630.
2009: Philippe Lefebvre; Bertrand Cariou; Fleur Lien; Folkert Kuipers; Bart Staels
Role of bile acids and bile acid receptors in metabolic regulation.
Physiological reviews 2009;89(1):147-91.
2009: Martijn O Hoeke; Jacqueline R M Plass; Janette Heegsma; Mariska Geuken; Duncan van Rijsbergen; Julius F W Baller; Folkert Kuipers; Han Moshage; Peter L M Jansen; Klaas Nico Faber
Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
Hepatology (Baltimore, Md.) 2009;49(1):151-9.
2009: Carlijn I Buis; Erwin Geuken; Dorien S Visser; Folkert Kuipers; Elizabeth B Haagsma; Henkjan J Verkade; Robert J Porte
Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures.
Journal of hepatology 2009;50(1):69-79.
2008: Maaike H Oosterveer; Theo H van Dijk; Aldo Grefhorst; Vincent Bloks; Rick Havinga; Folkert Kuipers; Dirk-Jan Reijngoud
Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice.
The Journal of biological chemistry 2008;283(37):25437-45.
2008: Hélène Duez; Jelske N van der Veen; Christian Duhem; Benoît Pourcet; Thierry Touvier; Coralie Fontaine; Bruno Derudas; Eric Baugé; Rick Havinga; Vincent Bloks; Henk Wolters; Fjodor H van der Sluijs; Björn Vennström; Folkert Kuipers; Bart Staels
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
Gastroenterology 2008;135(2):689-98.
2008: Folkert Kuipers; Albert K Groen
Chipping away at gallstones.
Nature medicine 2008;14(7):715-6.
2008: Astrid E van der Velde; Carlos Vrins; Karin van den Oever; Ingar Seemann; Ronald P J Oude Elferink; Miranda van Eck; Folkert Kuipers; Albert K Groen
Regulation of direct transintestinal cholesterol excretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(1):G203-G208.
2008: Robert H J Bandsma; Berthil H Prinsen; Monique de Sain van Der Velden; Jan Peter Rake; Theo Boer; G Peter A Smit; Dirk-Jan Reijngoud; Folkert Kuipers
Increased de novo lipogenesis and delayed conversion of large VLDL into intermediate density lipoprotein particles contribute to hyperlipidemia in glycogen storage disease type 1a.
Pediatric research 2008;63(6):702-7.
2008: Hilde Herrema; Terry G J Derks; Theo H Van Dijk; Vincent Bloks; Albert Gerding; Rick Havinga; Uwe J F Tietge; Michael Müller; G Peter A Smit; Folkert Kuipers; Dirk-Jan Reijngoud
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.
Hepatology (Baltimore, Md.) 2008;47(6):1894-904.
2008: Heleen M de Vogel-van den Bosch; Nicole J W de Wit; Guido J E J Hooiveld; Hanneke Vermeulen; Jelske N van der Veen; Sander M Houten; Folkert Kuipers; Michael Müller; Roelof van der Meer
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(5):G1171-80.
2008: Yan Liu; Rick Havinga; Feike R van der Leij; Renze Boverhof; Pieter J J Sauer; Folkert Kuipers; Frans Stellaard
Dexamethasone exposure of neonatal rats modulates biliary lipid secretion and hepatic expression of genes controlling bile acid metabolism in adulthood without interfering with primary bile acid kinetics.
Pediatric research 2008;63(4):375-81.
2008: Yan Liu; Harry van Goor; Rick Havinga; Julius F W Baller; Vincent Bloks; Feike R van der Leij; Pieter J J Sauer; Folkert Kuipers; gerjan navis; Martin H de Borst
Neonatal dexamethasone administration causes progressive renal damage due to induction of an early inflammatory response.
American journal of physiology. Renal physiology 2008;294(4):F768-76.
2008: Karlygash Abildayeva; Jimmy F P Berbée; Arjan Blokland; Paula J Jansen; Frans J Hoek; Onno Meijer; Dieter Lütjohann; Thomas Gautier; Thierry Pillot; Jan de Vente; Louis M Havekes; Frans C S Ramaekers; Folkert Kuipers; Patrick C N Rensen; Monique Mulder
Human apolipoprotein C-I expression in mice impairs learning and memory functions.
Journal of lipid research 2008;49(4):856-69.
2008: Janine K Kruit; A Lyndsay Drayer; Vincent Bloks; Nel R Blom; Sandra G Olthof; Pieter J J Sauer; Gerald de Haan; Ido P Kema; Edo Vellenga; Folkert Kuipers
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.
The Journal of biological chemistry 2008;283(10):6281-7.
2008: Terry G J Derks; Theo H van Dijk; Aldo Grefhorst; Jan Peter Rake; G Peter A Smit; Folkert Kuipers; Dirk-Jan Reijngoud
Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice.
Hepatology (Baltimore, Md.) 2008;47(3):1032-42.
2008: Marten H Hofker; Franco Bernini; Arnold von Eckardstein; Dilys Freeman; Joerg Heeren; Fredrik Karpe; Athina Kalopissis; Florian Kronenberg; Folkert Kuipers; Ken Lindstedt; Paolo Parini; Gertrud Schuster; Ko Willems van Dijk
European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.
Atherosclerosis 2008;197(1):471-9.
2008: Uwe J F Tietge; Niels Nijstad; Rick Havinga; Julius F W Baller; Fjodor H van der Sluijs; Vincent Bloks; Thomas Gautier; Folkert Kuipers
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Journal of lipid research 2008;49(3):563-71.
2007: Feike R van der Leij; Vincent Bloks; Aldo Grefhorst; Jildou Hoekstra; Albert Gerding; Krista Kooi; Frans Gerbens; Gerard te Meerman; Folkert Kuipers
Gene expression profiling in livers of mice after acute inhibition of beta-oxidation.
Genomics 2007;90(6):680-9.
2007: Bertrand Cariou; Emmanuel Bouchaert; Mouaadh Abdelkarim; Julie Dumont; Sandrine Caron; Jean-Charles Fruchart; Rémy Burcelin; Folkert Kuipers; Bart Staels
FXR-deficiency confers increased susceptibility to torpor.
FEBS letters 2007;581(27):5191-8.
2007: Astrid E van der Velde; Carlos Vrins; Karin van den Oever; Cindy Kunne; Ronald P J Oude Elferink; Folkert Kuipers; Albert K Groen
Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice.
Gastroenterology 2007;133(3):967-75.
2007: E Leonie Los; Henk Wolters; Frans Stellaard; Folkert Kuipers; Henkjan J Verkade; Edmond H H M Rings
Intestinal capacity to digest and absorb carbohydrates is maintained in a rat model of cholestasis.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(3):G615-22.
2007: Henkjan J Verkade; Rick Havinga; David J Shields; Henk Wolters; Vincent Bloks; Folkert Kuipers; Dennis E Vance; Luis B Agellon
The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion.
Journal of lipid research 2007;48(9):2058-64.
2007: Marten H Hofker; Laura Calabresi; Arnold von Eckardstein; Joerg Heeren; Fredrik Karpe; Athina Kalopissis; Florian Kronenberg; Folkert Kuipers; Ken Lindstedt; Paolo Parini; Gertrud Schuster; Ko Willems van Dijk
European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.
Atherosclerosis 2007;193(2):461-8.
2007: Karin E R Gooijert; Rick Havinga; Alida R Oosterloo-Duinkerken; Enge E A Venekamp-Hoolsema; Folkert Kuipers; Henkjan J Verkade
Stimulation of fecal fat excretion and the disposal of protoporphyrin in a murine model for erythropoietic protoporphyria.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(2):G510-6.
2007: Hilde Herrema; G Peter A Smit; Dirk-Jan Reijngoud; Folkert Kuipers
Does increased fatty acid oxidation enhance development of liver cirrhosis and progression to hepatocellular carcinoma in patients with glycogen storage disease type-III?
Journal of hepatology 2007;47(2):298-300; author reply 300-1.
2007: Torsten Plösch; E M E van Straten; Folkert Kuipers
Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?
Placenta 2007;28(7):604-10.
2007: Alan D Attie; Matthew Flowers; Jessica B Flowers; Albert K Groen; Folkert Kuipers; James M Ntambi
Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes.
Nutrition reviews 2007;65(6 Pt 2):S35-8.
2007: Folkert Kuipers; Johanna H M Stroeve; Sandrine Caron; Bart Staels
Bile acids, farnesoid X receptor, atherosclerosis and metabolic control.
Current opinion in lipidology 2007;18(3):289-97.
2007: Susan D P W M de Jonge-Peeters; Folkert Kuipers; Elisabeth G E de Vries; Edo Vellenga
ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance.
Critical reviews in oncology/hematology 2007;62(3):214-26.
2007: johannes aerts; Roelof Ottenhoff; Andrew S Powlson; Aldo Grefhorst; Martin van Eijk; Peter F Dubbelhuis; Jan Aten; Folkert Kuipers; Mireille J Serlie; Tom Wennekes; Jaswinder Sethi; Stephen O'Rahilly; Herman S Overkleeft
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Diabetes 2007;56(5):1341-9.
2007: Atsushi Nohara; Masa-aki Kawashiri; Thierry Claudel; Mihoko Mizuno; Masayuki Tsuchida; Mutsuko Takata; Shoji Katsuda; Kenji Miwa; Akihiro Inazu; Folkert Kuipers; Junji Kobayashi; Junji Koizumi; Masakazu Yamagishi; Hiroshi Mabuchi
High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):923-8.
2007: Yan Liu; Rick Havinga; Vincent Bloks; Julius F W Baller; Feike R van der Leij; Dirk-Jan Reijngoud; Pieter J J Sauer; Folkert Kuipers
Postnatal treatment with dexamethasone perturbs hepatic and cardiac energy metabolism and is associated with a sustained atherogenic plasma lipid profile in suckling rats.
Pediatric research 2007;61(2):165-70.
2007: Jelske N van der Veen; Rick Havinga; Vincent Bloks; Albert K Groen; Folkert Kuipers
Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha.
Journal of lipid research 2007;48(2):337-47.
2007: Alan D Attie; Matthew Flowers; Jessica B Flowers; Albert K Groen; Folkert Kuipers; James M Ntambi
Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes.
Novartis Foundation symposium 2007;286():47-53; discussion 54-7, 162-3, 196-203.
2007: Bart Staels; Folkert Kuipers
Bile acid sequestrants and the treatment of type 2 diabetes mellitus.
Drugs 2007;67(10):1383-92.
2007: Romi Ghose; Jaap Mulder; Richard J von Furstenberg; Sundararajah Thevananther; Folkert Kuipers; Saul J Karpen
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.
Journal of hepatology 2007;46(1):115-23.
2007: Thomas Gautier; Uwe J F Tietge; Renze Boverhof; Frank G Perton; Naig Le Guern; David Masson; Patrick Rensen; Louis M Havekes; Laurent Lagrost; Folkert Kuipers
Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein.
Journal of lipid research 2007;48(1):30-40.
2006: Fanny Lalloyer; Catherine Fiévet; Sophie Lestavel; Gérard Torpier; Jelske van der Veen; Véronique Touche; Stéphanie Bultel; Saïd Yous; Folkert Kuipers; Réjane Paumelle; Jean-Charles Fruchart; Bart Staels; Anne Tailleux
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2731-7.
2006: Elena Korsheninnikova; Gerard C M van der Zon; Peter J Voshol; G M Janssen; Louis M Havekes; Aldo Grefhorst; Folkert Kuipers; Dirk-Jan Reijngoud; Johannes A Romijn; D Margriet Ouwens; J Antonie Maassen
Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice.
Diabetologia 2006;49(12):3049-57.
2006: Matthew Flowers; Albert K Groen; Angie Tebon Oler; Mark P Keller; YounJeong Choi; Kathryn L Schueler; Oliver C Richards; Hong Lan; Makoto Miyazaki; Folkert Kuipers; Christina Kendziorski; James M Ntambi; Alan D Attie
Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.
Journal of lipid research 2006;47(12):2668-80.
2006: Marion A M den Boer; Peter J Voshol; Folkert Kuipers; Johannes A Romijn; Louis M Havekes
Hepatic glucose production is more sensitive to insulin-mediated inhibition than hepatic VLDL-triglyceride production.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1360-4.
2006: Janine K Kruit; Albert K Groen; Theo Van berkel; Folkert Kuipers
Emerging roles of the intestine in control of cholesterol metabolism.
World journal of gastroenterology : WJG 2006;12(40):6429-39.
2006: Ruud Out; Menno Hoekstra; Reeni B Hildebrand; Janine K Kruit; Illiana Meurs; Zhaosha Li; Folkert Kuipers; Theo Van berkel; Miranda van Eck
Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2295-300.
2006: Marion A M den Boer; Peter J Voshol; Janny P Schröder-van der Elst; Elena Korsheninnikova; D Margriet Ouwens; Folkert Kuipers; Louis M Havekes; Johannes A Romijn
Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice.
Endocrinology 2006;147(10):4553-8.
2006: Liam R Brunham; Janine K Kruit; Terry D Pape; John S Parks; Folkert Kuipers; Michael R Hayden
Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.
Circulation research 2006;99(7):672-4.
2006: Torsten Plösch; Jelske N van der Veen; Rick Havinga; Nicolette C A Huijkman; Vincent Bloks; Folkert Kuipers
Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G414-23.
2006: Torsten Plösch; Janine K Kruit; Vincent Bloks; Nicolette C A Huijkman; Rick Havinga; Guus S Duchateau; Yuguang Lin; Folkert Kuipers
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter.
The Journal of nutrition 2006;136(8):2135-40.
2006: Fanny Lalloyer; Brigitte Vandewalle; Frédéric Percevault; Gérard Torpier; Julie Kerr Conte; Maaike Oosterveer; Réjane Paumelle; Jean-Charles Fruchart; Folkert Kuipers; François Pattou; Catherine Fiévet; Bart Staels
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Diabetes 2006;55(6):1605-13.
2006: Anniek Werner; Rick Havinga; Frank Perton; Folkert Kuipers; Henkjan J Verkade
Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1177-85.
2006: Karlygash Abildayeva; Paula J Jansen; Veronica Hirsch-Reinshagen; Vincent Bloks; Arjen Bakker; Frans C S Ramaekers; Jan de Vente; Albert K Groen; Cheryl L Wellington; Folkert Kuipers; Monique Mulder
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.
The Journal of biological chemistry 2006;281(18):12799-808.
2006: Susan D P W M Peeters; Dorina M van der Kolk; Gerald de Haan; Leonid V Bystrykh; Folkert Kuipers; Elisabeth G E de Vries; Edo Vellenga
Selective expression of cholesterol metabolism genes in normal CD34+CD38- cells with a heterogeneous expression pattern in AML cells.
Experimental hematology 2006;34(5):622-30.
2006: Bertrand Cariou; Kirsten van Harmelen; Daniel Duran-Sandoval; Theo H Van Dijk; Aldo Grefhorst; Mouaadh Abdelkarim; Sandrine Caron; Gérard Torpier; Jean-Charles Fruchart; Frank J Gonzalez; Folkert Kuipers; Bart Staels
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
The Journal of biological chemistry 2006;281(16):11039-49.
2006: Paula J Jansen; Dieter Lütjohann; Karlygash Abildayeva; Tim Vanmierlo; Torsten Plösch; Jogchum Plat; Klaus Von Bergmann; Albert K Groen; Frans C S Ramaekers; Folkert Kuipers; Monique Mulder
Dietary plant sterols accumulate in the brain.
Biochimica et biophysica acta 2006;1761(4):445-53.
2006: Iris J A M Jonkers; August Smelt; Hans M G Princen; Folkert Kuipers; Johannes A Romijn; Renze Boverhof; A A M Masclee; Frans Stellaard
Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.
The Journal of nutrition 2006;136(4):987-91.
2006: Liam R Brunham; Janine K Kruit; Jahangir Iqbal; Catherine Fievet; Jenelle M Timmins; Terry D Pape; Bryan Coburn; Nagat Bissada; Bart Staels; Albert K Groen; M Mahmood Hussain; John S Parks; Folkert Kuipers; Michael R Hayden
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
The Journal of clinical investigation 2006;116(4):1052-62.
2006: Stéphane Mandard; Fokko Zandbergen; Esther van Straten; Walter Wahli; Folkert Kuipers; Michael Müller; Sander Kersten
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
The Journal of biological chemistry 2006;281(2):934-44.
2006: Marion A M den Boer; Jimmy F P Berbée; Peter Reiss; Marc van der Valk; Peter J Voshol; Folkert Kuipers; Louis M Havekes; Patrick Rensen; Johannes A Romijn
Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):124-9.
2005: Gertjan van Dijk; Koert de Vries; Csaba Nyakas; Bauke Buwalda; Tiziana Adage; Folkert Kuipers; Martien J H Kas; Roger A H Adan; Charles William Wilkinson; Todd E Thiele; Anton J W Scheurink
Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.
Endocrinology 2005;146(12):5247-56.
2005: Illiana Meurs; Menno Hoekstra; Eva J A van Wanrooij; Reeni B Hildebrand; Johan Kuiper; Folkert Kuipers; Max R Hardeman; Theo Van berkel; Miranda van Eck
HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes.
Experimental hematology 2005;33(11):1309-19.
2005: Erwin Geuken; Dorien S Visser; Henri G D Leuvenink; Koert P de Jong; Paul M J G Peeters; Maarten J H Slooff; Folkert Kuipers; Robert J Porte
Hepatic expression of ABC transporters G5 and G8 does not correlate with biliary cholesterol secretion in liver transplant patients.
Hepatology (Baltimore, Md.) 2005;42(5):1166-74.
2005: Aldo Grefhorst; Theo H Van Dijk; Anke Hammer; Fjodor H van der Sluijs; Rick Havinga; Louis M Havekes; Johannes A Romijn; Pieter Groot; Dirk-Jan Reijngoud; Folkert Kuipers
Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.
American journal of physiology. Endocrinology and metabolism 2005;289(5):E829-38.
2005: Thierry Claudel; Bart Staels; Folkert Kuipers
The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(10):2020-30.
2005: Jeltje R Goudriaan; Marion A M den Boer; Patrick Rensen; Maria Febbraio; Folkert Kuipers; Johannes A Romijn; Louis M Havekes; Peter J Voshol
CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance.
Journal of lipid research 2005;46(10):2175-81.
2005: Aldo Grefhorst; Jildou Hoekstra; Terry G J Derks; D Margriet Ouwens; Julius F W Baller; Rick Havinga; Louis M Havekes; Johannes A Romijn; Folkert Kuipers
Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(3):G592-8.
2005: Daniel Duran-Sandoval; Bertrand Cariou; Frédéric Percevault; Nathalie Hennuyer; Aldo Grefhorst; Theo H Van Dijk; Frank J Gonzalez; Jean-Charles Fruchart; Folkert Kuipers; Bart Staels
The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.
The Journal of biological chemistry 2005;280(33):29971-9.
2005: Bertrand Cariou; Kirsten van Harmelen; Daniel Duran-Sandoval; Theo H Van Dijk; Aldo Grefhorst; Emmanuel Bouchaert; Jean-Charles Fruchart; Frank J Gonzalez; Folkert Kuipers; Bart Staels
Transient impairment of the adaptive response to fasting in FXR-deficient mice.
FEBS letters 2005;579(19):4076-80.
2005: Frans Stellaard; Folkert Kuipers
Assessment of modes of action and efficacy of plasma cholesterol-lowering drugs: measurement of cholesterol absorption, cholesterol synthesis and bile acid synthesis and turnover using novel stable isotope techniques.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(2):209-18.
2005: Christian V Hulzebos; Peter J Voshol; Henk Wolters; Janine K Kruit; Roelof Ottenhof; Albert K Groen; Frans Stellaard; Henkjan J Verkade; Folkert Kuipers
Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(3):604-12.
2005: Anniek Werner; Rick Havinga; Trijnie Bos; Vincent Bloks; Folkert Kuipers; Henkjan J Verkade
Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(6):G1150-8.
2005: Ilse Duivenvoorden; Bas Teusink; Patrick Rensen; Folkert Kuipers; Johannes A Romijn; Louis M Havekes; Peter J Voshol
Acute inhibition of hepatic beta-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity.
Journal of lipid research 2005;46(5):988-93.
2005: Xuedong Yan; Folkert Kuipers; Louis M Havekes; Rick Havinga; Bert Dontje; Klaas Poelstra; Gerrit L Scherphof; Jan A A M Kamps
The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse.
Biochemical and biophysical research communications 2005;328(1):57-62.
2005: Bertrand Cariou; Daniel Duran-Sandoval; Folkert Kuipers; Bart Staels
Farnesoid X receptor: a new player in glucose metabolism?
Endocrinology 2005;146(3):981-3.
2005: Jelske N van der Veen; Janine K Kruit; Rick Havinga; Julius F W Baller; Giovanna Chimini; Sophie Lestavel; Bart Staels; Pieter Groot; Albert K Groen; Folkert Kuipers
Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.
Journal of lipid research 2005;46(3):526-34.
2005: Torsten Plösch; Astrid Kosters; Albert K Groen; Folkert Kuipers
The ABC of hepatic and intestinal cholesterol transport.
Handbook of experimental pharmacology 2005;(170):465-82.
2005: Janine K Kruit; Torsten Plösch; Rick Havinga; Renze Boverhof; Pieter Groot; Albert K Groen; Folkert Kuipers
Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.
Gastroenterology 2005;128(1):147-56.
2005: Ekkehard Sturm; Rick Havinga; Julius F W Baller; Henk Wolters; Nico van Rooijen; Jan A A M Kamps; Henkjan J Verkade; Saul J Karpen; Folkert Kuipers
Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.
Journal of hepatology 2005;42(1):102-9.
2005: Dianne J M Delsing; Sabine M Post; Martine Groenendijk; Karianne Solaas; Hans van der Boom; Wim van Duyvenvoorde; Elly C M de Wit; Vincent Bloks; Folkert Kuipers; Louis M Havekes; Hans M G Princen
Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice.
Journal of cardiovascular pharmacology 2005;45(1):53-60.
2004: Erwin Geuken; Dorien S Visser; Folkert Kuipers; Hans Blokzijl; Henri G D Leuvenink; Koert P de Jong; Paul M J G Peeters; Peter L M Jansen; Maarten J H Slooff; Annette S H Gouw; Robert J Porte
Rapid increase of bile salt secretion is associated with bile duct injury after human liver transplantation.
Journal of hepatology 2004;41(6):1017-25.
2004: Gideon Allick; Peter H Bisschop; Mariëtte T Ackermans; Erik Endert; Alfred J Meijer; Folkert Kuipers; Hans P Sauerwein; Johannes A Romijn
A low-carbohydrate/high-fat diet improves glucoregulation in type 2 diabetes mellitus by reducing postabsorptive glycogenolysis.
The Journal of clinical endocrinology and metabolism 2004;89(12):6193-7.
2004: Folkert Kuipers; Thierry Claudel; Ekkehard Sturm; Bart Staels
The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism.
Reviews in endocrine & metabolic disorders 2004;5(4):319-26.
2004: Robert H J Bandsma; Aldo Grefhorst; Theo H Van Dijk; Fjodor H van der Sluijs; A Hammer; Dirk-Jan Reijngoud; Folkert Kuipers
Enhanced glucose cycling and suppressed de novo synthesis of glucose-6-phosphate result in a net unchanged hepatic glucose output in ob/ob mice.
Diabetologia 2004;47(11):2022-31.
2004: Lorraine N Renfurm; Robert H J Bandsma; Henkjan J Verkade; Christian V Hulzebos; Theo H Van Dijk; Theo S Boer; Frans Stellaard; Folkert Kuipers; Pieter J J Sauer
Cholesterol synthesis and de novo lipogenesis in premature infants determined by mass isotopomer distribution analysis.
Pediatric research 2004;56(4):602-7.
2004: Thierry Claudel; Ekkehard Sturm; Folkert Kuipers; Bart Staels
The farnesoid X receptor: a novel drug target?
Expert opinion on investigational drugs 2004;13(9):1135-48.
2004: N Harry Hendrikse; Folkert Kuipers; Coby Meijer; Rick Havinga; C M A Bijleveld; Winette T A van der Graaf; Willem Vaalburg; Elisabeth G E de Vries
In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.
Cancer chemotherapy and pharmacology 2004;54(2):131-8.
2004: Christian V Hulzebos; C M A Bijleveld; Frans Stellaard; Folkert Kuipers; Vaclav Fidler; Maarten J H Slooff; Paul M J G Peeters; Pieter J J Sauer; Henkjan J Verkade
Cyclosporine A-induced reduction of bile salt synthesis associated with increased plasma lipids in children after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(7):872-80.
2004: Anniek Werner; Rick Havinga; Folkert Kuipers; Henkjan J Verkade
Treatment of EFA deficiency with dietary triglycerides or phospholipids in a murine model of extrahepatic cholestasis.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(5):G822-32.
2004: Peter H Bisschop; Robert H J Bandsma; Frans Stellaard; Anke ter Harmsel; Alfred J Meijer; Hans P Sauerwein; Folkert Kuipers; Johannes A Romijn
Low-fat, high-carbohydrate and high-fat, low-carbohydrate diets decrease primary bile acid synthesis in humans.
The American journal of clinical nutrition 2004;79(4):570-6.
2004: Daniel Duran-Sandoval; Gisèle Mautino; Geneviève Martin; Frédéric Percevault; Olivier Barbier; Jean-Charles Fruchart; Folkert Kuipers; Bart Staels
Glucose regulates the expression of the farnesoid X receptor in liver.
Diabetes 2004;53(4):890-8.
2004: Arjen Mensenkamp; Marja J A van Luyn; Rick Havinga; Bas Teusink; Ian J Waterman; Christopher J Mann; Baukje M Elzinga; Henkjan J Verkade; Victor A Zammit; Louis M Havekes; Carol C Shoulders; Folkert Kuipers
The transport of triglycerides through the secretory pathway of hepatocytes is impaired in apolipoprotein E deficient mice.
Journal of hepatology 2004;40(4):599-606.
2004: M den Boer; Peter J Voshol; Folkert Kuipers; Louis M Havekes; Johannes A Romijn
Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):644-9.
2004: Marie-Pierre Ruffin; Tiziana Adage; Folkert Kuipers; Jan H Strubbe; Anton J W Scheurink; Gertjan van Dijk
Feeding and temperature responses to intravenous leptin infusion are differential predictors of obesity in rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(4):R756-63.
2004: Tomoji Nishioka; Rick Having; Susumu Tazuma; Frans Stellaard; Folkert Kuipers; Henkjan J Verkade
Administration of phosphatidylcholine-cholesterol liposomes partially reconstitutes fat absorption in chronically bile-diverted rats.
Biochimica et biophysica acta 2004;1636(2-3):90-8.
2004: Robert H J Bandsma; Theo H Van Dijk; Anke ter Harmsel At; Tineke Kok; Dirk-Jan Reijngoud; Bart Staels; Folkert Kuipers
Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short term fast.
The Journal of biological chemistry 2004;279(10):8930-7.
2004: Marten H Hofker; L Calabresi; M Jauhiainen; Johannes Nimpf; M Rudling; P Talmud; Vincent Mooser; Geesje M Dallinga-Thie; Arnold von Eckardstein; Bart Staels; Fredrik Karpe; Folkert Kuipers
European Lipoprotein Club: report of the 26th ELC Annual Conference, Tutzing, 8-11 September 2003.
Atherosclerosis 2004;173(1):125-34.
2004: Albert K Groen; Ronald P J Oude Elferink; Henkian J Verkade; Folkert Kuipers
The ins and outs of reverse cholesterol transport.
Annals of medicine 2004;36(2):135-45.
2004: Torsten Plösch; Vincent Bloks; Yuko Terasawa; Sara Berdy; Karen Siegler; Fjodor H van der Sluijs; Ido P Kema; Albert K Groen; Bei Shan; Folkert Kuipers; Margrit Schwarz; Margrit Schwartz
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
Gastroenterology 2004;126(1):290-300.
2004: Vincent Bloks; W M Bakker-Van Waarde; Henkjan J Verkade; Ido P Kema; Henk Wolters; Edwin Vink; Albert K Groen; Folkert Kuipers
Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes.
Diabetologia 2004;47(1):104-12.
2003: Baukje M Elzinga; Julius F W Baller; Arjen Mensenkamp; Zemin Yao; Luis B Agellon; Folkert Kuipers; Henkjan J Verkade
Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.
Biochimica et biophysica acta 2003;1635(2-3):93-103.
2003: Theo H Van Dijk; Theo S Boer; Rick Havinga; Frans Stellaard; Folkert Kuipers; Dirk-Jan Reijngoud
Quantification of hepatic carbohydrate metabolism in conscious mice using serial blood and urine spots.
Analytical biochemistry 2003;322(1):1-13.
2003: Tineke Kok; Christian V Hulzebos; Henk Wolters; Rick Havinga; Luis B Agellon; Frans Stellaard; Bei Shan; Margrit Schwarz; Folkert Kuipers
Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein.
The Journal of biological chemistry 2003;278(43):41930-7.
2003: Peter H Bisschop; Monique G M de Sain-Van Der Velden; Frans Stellaard; Folkert Kuipers; Alfred J Meijer; Hans P Sauerwein; Johannes A Romijn
Dietary carbohydrate deprivation increases 24-hour nitrogen excretion without affecting postabsorptive hepatic or whole body protein metabolism in healthy men.
The Journal of clinical endocrinology and metabolism 2003;88(8):3801-5.
2003: Jenny E Ros; Tania Roskams; Mariska Geuken; Rick Havinga; P L Splinter; Bryon E Petersen; N F LaRusso; Dorina M van der Kolk; Folkert Kuipers; Klaas Nico Faber; Michael Müller; Peter L M Jansen
ATP binding cassette transporter gene expression in rat liver progenitor cells.
Gut 2003;52(7):1060-7.
2003: Miranda van Eck; Jaap Twisk; Menno Hoekstra; Brechje T Van Rij; Christian A C Van der Lans; I Sophie T Bos; J Kar Kruijt; Folkert Kuipers; Theo Van berkel
Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver.
The Journal of biological chemistry 2003;278(26):23699-705.
2003: Olivier Barbier; Inés Pineda Torra; Audrey Sirvent; Thierry Claudel; Christophe Blanquart; Daniel Duran-Sandoval; Folkert Kuipers; Vladimir Kosykh; Jean-Charles Fruchart; Bart Staels
FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.
Gastroenterology 2003;124(7):1926-40.
2003: Astrid Kosters; Raoul J J M Frijters; Frank G Schaap; Edwin Vink; Torsten Plösch; Roelof Ottenhoff; Milan Jirsa; Iris M De Cuyper; Folkert Kuipers; Albert K Groen
Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice.
Journal of hepatology 2003;38(6):710-6.
2003: Coen H Wiegman; Robert H J Bandsma; Margriet Ouwens; Fjodor H van der Sluijs; Rick Havinga; Theo S Boer; Dirk-Jan Reijngoud; Johannes A Romijn; Folkert Kuipers
Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin.
Diabetes 2003;52(5):1081-9.
2003: Louis Libbrecht; Leo Meerman; Folkert Kuipers; Tania Roskams; Valeer Desmet; Peter Jansen
Liver pathology and hepatocarcinogenesis in a long-term mouse model of erythropoietic protoporphyria.
The Journal of pathology 2003;199(2):191-200.
2003: Tineke Kok; Vincent Bloks; Henk Wolters; Rick Havinga; Peter L M Jansen; Bart Staels; Folkert Kuipers
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
The Biochemical journal 2003;369(Pt 3):539-47.
2003: Tineke Kok; Henk Wolters; Vincent Bloks; Rick Havinga; Peter L M Jansen; Bart Staels; Folkert Kuipers
Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse.
Gastroenterology 2003;124(1):160-71.
2003: Christian V Hulzebos; Henk Wolters; Torsten Plösch; Werner Kramer; Siegfried Stengelin; Frans Stellaard; Pieter J J Sauer; Henkjan J Verkade; Folkert Kuipers
Cyclosporin a and enterohepatic circulation of bile salts in rats: decreased cholate synthesis but increased intestinal reabsorption.
The Journal of pharmacology and experimental therapeutics 2003;304(1):356-63.
2003: Iris J A M Jonkers; August Smelt; Michael Ledeboer; M E Hollum; Izak Biemond; Folkert Kuipers; Frans Stellaard; Renze Boverhof; A Edo Meinders; C H B W Lamers; A A M Masclee
Gall bladder dysmotility: a risk factor for gall stone formation in hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and fish oil.
Gut 2003;52(1):109-15.
2002: johan jonker; Marije Buitelaar; Els Wagenaar; Martin van der Valk; George L Scheffer; Rik J Scheper; Torsten Plosch; Folkert Kuipers; Ronald P J Oude Elferink; Hilde Rosing; Jos H Beijnen; Alfred H Schinkel
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15649-54.
2002: Henk Wolters; Baukje M Elzinga; Julius F W Baller; Renze Boverhof; Margrit Schwarz; Bruno Stieger; Henkjan J Verkade; Folkert Kuipers
Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice.
Journal of hepatology 2002;37(5):556-63.
2002: Baukje M Elzinga; Rick Havinga; Julius F W Baller; Henk Wolters; Vincent Bloks; Arjen Mensenkamp; Folkert Kuipers; Henkjan J Verkade
The role of transhepatic bile salt flux in the control of hepatic secretion of triacylglycerol-rich lipoproteins in vivo in rodents.
Biochimica et biophysica acta 2002;1573(1):9-20.
2002: Robert H J Bandsma; G Peter A Smit; Folkert Kuipers
Disturbed lipid metabolism in glycogen storage disease type 1.
European journal of pediatrics 2002;161 Suppl 1():S65-9.
2002: Anniek Werner; Deanne M Minich; Rick Havinga; Vincent Bloks; Harry van Goor; Folkert Kuipers; Henkjan J Verkade
Fat malabsorption in essential fatty acid-deficient mice is not due to impaired bile formation.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G900-8.
2002: Lori A Gustafson; Folkert Kuipers; Coen H Wiegman; Hans P Sauerwein; Johannes A Romijn; Alfred J Meijer
Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity.
Journal of hepatology 2002;37(4):425-31.
2002: Torsten Plōsch; Tineke Kok; Vincent Bloks; Martin J Smit; Rick Havinga; Giovanna Chimini; Albert K Groen; Folkert Kuipers
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.
The Journal of biological chemistry 2002;277(37):33870-7.
2002: Aldo Grefhorst; Baukje M Elzinga; Peter J Voshol; Torsten Plösch; Tineke Kok; Vincent Bloks; Fjodor H van der Sluijs; Louis M Havekes; Johannes A Romijn; Henkjan J Verkade; Folkert Kuipers
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
The Journal of biological chemistry 2002;277(37):34182-90.
2002: Peter H Bisschop; Mariëtte T Ackermans; Erik Endert; An F C Ruiter; Alfred J Meijer; Folkert Kuipers; Hans P Sauerwein; Johannes A Romijn
The effect of carbohydrate and fat variation in euenergetic diets on postabsorptive free fatty acid release.
The British journal of nutrition 2002;87(6):555-9.
2002: Willie M van Waarde; Henkjan J Verkade; Henk Wolters; Rick Havinga; Julius F W Baller; Vincent Bloks; Michael Müller; Pieter J J Sauer; Folkert Kuipers
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats.
Gastroenterology 2002;122(7):1842-52.
2002: Thierry Claudel; Ekkehard Sturm; Hélène Duez; Inés Pineda Torra; Audrey Sirvent; Vladimir Kosykh; Jean-Charles Fruchart; Jean Dallongeville; Dean W Hum; Folkert Kuipers; Bart Staels
Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.
The Journal of clinical investigation 2002;109(7):961-71.
2002: Robert H J Bandsma; Jan Peter Rake; Gepke Visser; Richard A Neese; Marc K Hellerstein; Wim van Duyvenvoorde; Hans M G Princen; Frans Stellaard; G Peter A Smit; Folkert Kuipers
Increased lipogenesis and resistance of lipoproteins to oxidative modification in two patients with glycogen storage disease type 1a.
The Journal of pediatrics 2002;140(2):256-60.
2002: Torsten Plösch; Vincent Bloks; Julius F W Baller; Rick Havinga; Henkjan J Verkade; Peter L M Jansen; Folkert Kuipers
Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.
Hepatology (Baltimore, Md.) 2002;35(2):299-306.
2002: Ekkehard Sturm; Casper F M Franssen; Annette S H Gouw; Bart Staels; Renze Boverhof; RJ de Knegt; Frans Stellaard; C M A Bijleveld; Folkert Kuipers
Extracorporal albumin dialysis (MARS) improves cholestasis and normalizes low apo A-I levels in a patient with benign recurrent intrahepatic cholestasis (BRIC).
Liver 2002;22 Suppl 2():72-5.
2001: Arjen Mensenkamp; Louis M Havekes; Johannes A Romijn; Folkert Kuipers
Hepatic steatosis and very low density lipoprotein secretion: the involvement of apolipoprotein E.
Journal of hepatology 2001;35(6):816-22.
2001: Bas Teusink; Arjen Mensenkamp; H van der Boom; Folkert Kuipers; Ko Willems van Dijk; Louis M Havekes
Stimulation of the in vivo production of very low density lipoproteins by apolipoprotein E is independent of the presence of the low density lipoprotein receptor.
The Journal of biological chemistry 2001;276(44):40693-7.
2001: Christian V Hulzebos; L Renfurm; Robert H J Bandsma; Henkjan J Verkade; Theo S Boer; Renze Boverhof; H Tanaka; Igor Mierau; Pieter J J Sauer; Folkert Kuipers; Frans Stellaard
Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans.
Journal of lipid research 2001;42(11):1923-9.
2001: Sabine M Post; H Duez; Philippe Gervois; Bart Staels; Folkert Kuipers; Hans M G Princen
Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1840-5.
2001: Robert H J Bandsma; Coen H Wiegman; Andreas W Herling; Hans-Joerg burgerh; A ter Harmsel; Alfred J Meijer; Johannes A Romijn; Dirk-Jan Reijngoud; Folkert Kuipers
Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats.
Diabetes 2001;50(11):2591-7.
2001: Lori A Gustafson; M Neeft; Dirk-Jan Reijngoud; Folkert Kuipers; Hans P Sauerwein; Johannes A Romijn; Andreas W Herling; Hans-Joerg burgerh; Alfred J Meijer
Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.
The Biochemical journal 2001;358(Pt 3):665-71.
2001: Albert K Groen; Vincent Bloks; R H Bandsma; Roelof Ottenhoff; Giovanna Chimini; Folkert Kuipers
Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL.
The Journal of clinical investigation 2001;108(6):843-50.
2001: Arjen Mensenkamp; Bas Teusink; Julius F W Baller; Henk Wolters; Rick Havinga; Ko Willems van Dijk; Louis M Havekes; Folkert Kuipers
Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(8):1366-72.
2001: Theo H Van Dijk; Fjodor H van der Sluijs; Coen H Wiegman; Julius F W Baller; Lori A Gustafson; Hans-Joerg burgerh; Andreas W Herling; Folkert Kuipers; Alfred J Meijer; Dirk-Jan Reijngoud
Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.
The Journal of biological chemistry 2001;276(28):25727-35.
2001: Jenny E Ros; J D Schuetz; Mariska Geuken; K Streetz; Han Moshage; Folkert Kuipers; M P Manns; Peter L M Jansen; C Trautwein; Michael Müller
Induction of Mdr1b expression by tumor necrosis factor-alpha in rat liver cells is independent of p53 but requires NF-kappaB signaling.
Hepatology (Baltimore, Md.) 2001;33(6):1425-31.
2001: Peter J Voshol; Margrit Schwarz; A Rigotti; M Krieger; Albert K Groen; Folkert Kuipers
Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine.
The Biochemical journal 2001;356(Pt 2):317-25.
2001: Tiziana Adage; Anton J W Scheurink; Sietse F De Boer; Koert de Vries; JP Konsman; Folkert Kuipers; Roger A H Adan; Denis Baskin; Michael W Schwartz; Gertjan van Dijk
Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):3639-45.
2001: Annemieke Smit-van Oosten; gerjan navis; Coen A Stegeman; J A Joles; Pieter A Klok; Folkert Kuipers; Anton T M G Tiebosch; Harry van Goor
Chronic blockade of angiotensin II action prevents glomerulosclerosis, but induces graft vasculopathy in experimental kidney transplantation.
The Journal of pathology 2001;194(1):122-9.
2001: Peter H Bisschop; Jesse de Metz; Mariëtte T Ackermans; Erik Endert; H Pijl; Folkert Kuipers; Alfred J Meijer; Hans P Sauerwein; Johannes A Romijn
Dietary fat content alters insulin-mediated glucose metabolism in healthy men.
The American journal of clinical nutrition 2001;73(3):554-9.
2001: Peter J Voshol; NR Koopen; J Marleen L de Vree; Rick Havinga; Hans M G Princen; Ronald P J Oude Elferink; Albert K Groen; Folkert Kuipers
Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice.
Journal of hepatology 2001;34(2):202-9.
2001: Vincent Bloks; Torsten Plösch; Harry van Goor; Han Roelofsen; Julius F W Baller; Rick Havinga; Henkjan J Verkade; Arie Van Tol; Peter L M Jansen; Folkert Kuipers
Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice.
Journal of lipid research 2001;42(1):41-50.
2000: Deanne M Minich; Rick Havinga; Frans Stellaard; roel vonk; Folkert Kuipers; Henkjan J Verkade
Intestinal absorption and postabsorptive metabolism of linoleic acid in rats with short-term bile duct ligation.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1242-8.
2000: bert benthem; K Keizer; C H Wiegman; Jan H Strubbe; AB Steffens; Folkert Kuipers; Anton J W Scheurink
Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation.
American journal of physiology. Endocrinology and metabolism 2000;279(6):E1286-93.
2000: Han Roelofsen; Henk Wolters; M J Van Luyn; N Miura; Folkert Kuipers; roel vonk
Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion.
Gastroenterology 2000;119(3):782-93.
2000: Arjen Mensenkamp; Marja J A van Luyn; Harry van Goor; Vincent Bloks; Frank Apostel; Jobst Greeve; Marten H Hofker; MC Jong; Bart J M van Vlijmen; Louis M Havekes; Folkert Kuipers
Hepatic lipid accumulation, altered very low density lipoprotein formation and apolipoprotein E deposition in apolipoprotein E3-Leiden transgenic mice.
Journal of hepatology 2000;33(2):189-98.
2000: M Kalivianakis; Deanne M Minich; Rick Havinga; Folkert Kuipers; Frans Stellaard; roel vonk; Henkjan J Verkade
Detection of impaired intestinal absorption of long-chain fatty acids: validation studies of a novel test in a rat model of fat malabsorption.
The American journal of clinical nutrition 2000;72(1):174-80.
2000: Peter H Bisschop; AM Pereira Arias; Mariëtte T Ackermans; Erik Endert; H Pijl; Folkert Kuipers; Alfred J Meijer; Hans P Sauerwein; Johannes A Romijn
The effects of carbohydrate variation in isocaloric diets on glycogenolysis and gluconeogenesis in healthy men.
The Journal of clinical endocrinology and metabolism 2000;85(5):1963-7.
2000: Robert H J Bandsma; Folkert Kuipers; roel vonk; Renze Boverhof; Pieter J J Sauer; G T Nagel; Henk Elzinga; Richard A Neese; Marc K Hellerstein; Frans Stellaard
The contribution of newly synthesized cholesterol to bile salt synthesis in rats quantified by mass isotopomer distribution analysis.
Biochimica et biophysica acta 2000;1483(3):343-51.
2000: Peter J Voshol; Deanne M Minich; Rick Havinga; Ronald P J Oude Elferink; Henkjan J Verkade; Albert K Groen; Folkert Kuipers
Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Gastroenterology 2000;118(1):173-82.
1999: Arjen Mensenkamp; MC Jong; Harry van Goor; Marja J A van Luyn; Vincent Bloks; Rick Havinga; Peter J Voshol; Marten H Hofker; Ko Willems van Dijk; Louis M Havekes; Folkert Kuipers
Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver.
The Journal of biological chemistry 1999;274(50):35711-8.
1999: M Schaefer; Han Roelofsen; Henk Wolters; W J Hofmann; Michael Müller; Folkert Kuipers; W Stremmel; roel vonk
Localization of the Wilson's disease protein in human liver.
Gastroenterology 1999;117(6):1380-5.
1999: Peter L M Jansen; Sandra S Strautnieks; Emmanuel Jacquemin; michelle hadchouel; EM Sokal; Guido J E J Hooiveld; J H Koning; A de Jager-Krikken; Folkert Kuipers; Frans Stellaard; C M A Bijleveld; Annette S H Gouw; Harry van Goor; Richard John Thompson; Michael Müller
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.
Gastroenterology 1999;117(6):1370-9.
1999: bert benthem; Folkert Kuipers; AB Steffens; Anton J W Scheurink
Excessive portal venous supply of long-chain free fatty acids to the liver, leading to hypothalamus-pituitary-adrenal-axis and sympathetic activation as a key to the development of syndrome X. A proposed concept for the induction of syndrome X.
Annals of the New York Academy of Sciences 1999;892():308-11.
1999: Deanne M Minich; Peter J Voshol; Rick Havinga; Frans Stellaard; Folkert Kuipers; roel vonk; Henkjan J Verkade
Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice.
Biochimica et biophysica acta 1999;1441(1):14-22.
1999: M Kalivianakis; Jan M Elstrodt; Rick Havinga; Folkert Kuipers; Frans Stellaard; Pieter J J Sauer; roel vonk; Henkjan J Verkade
Validation in an animal model of the carbon 13-labeled mixed triglyceride breath test for the detection of intestinal fat malabsorption.
The Journal of pediatrics 1999;135(4):444-50.
1999: L Meerman; NR Koopen; Vincent Bloks; Harry van Goor; Rick Havinga; B G Wolthers; Werner Kramer; Siegfried Stengelin; Michael Müller; Folkert Kuipers; Peter L M Jansen
Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria.
Gastroenterology 1999;117(3):696-705.
1999: Guido J E J Hooiveld; TA Vos; G L Scheffer; Harry van Goor; H Koning; Vincent Bloks; Annemarieke E Loot; Dirk K F Meijer; Peter L M Jansen; Folkert Kuipers; Michael Müller
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats.
Gastroenterology 1999;117(3):678-87.
1999: Sabine M Post; J P Zoeteweij; M H Bos; Elly C M de Wit; Rick Havinga; Folkert Kuipers; Hans M G Princen
Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
Hepatology (Baltimore, Md.) 1999;30(2):491-500.
1999: TA Vos; Jenny E Ros; Rick Havinga; Han Moshage; Folkert Kuipers; Peter L M Jansen; Michael Müller
Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats.
Hepatology (Baltimore, Md.) 1999;29(6):1833-9.
1999: Deanne M Minich; M Kalivianakis; Rick Havinga; Harry van Goor; Frans Stellaard; roel vonk; Folkert Kuipers; Henkjan J Verkade
Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid.
Biochimica et biophysica acta 1999;1438(1):111-9.
1999: TA Vos; Harry van Goor; LM Tuyt; A de Jager-Krikken; R Leuvenink; Folkert Kuipers; Peter L M Jansen; Han Moshage
Expression of inducible nitric oxide synthase in endotoxemic rat hepatocytes is dependent on the cellular glutathione status.
Hepatology (Baltimore, Md.) 1999;29(2):421-6.
1999: NR Koopen; Henk Wolters; Peter J Voshol; Bruno Stieger; roel vonk; Peter Meier; Folkert Kuipers; B Hagenbuch
Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice.
Journal of hepatology 1999;30(1):14-21.
1999: NR Koopen; Sabine M Post; Henk Wolters; Rick Havinga; Frans Stellaard; Renze Boverhof; Folkert Kuipers; Hans M G Princen
Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat.
Journal of lipid research 1999;40(1):100-8.
1998: Monique G M de Sain-Van Der Velden; ton rabelink; MM Gadellaa; Henk Elzinga; Dirk-Jan Reijngoud; Folkert Kuipers; Frans Stellaard
In vivo determination of very-low-density lipoprotein-apolipoprotein B100 secretion rates in humans with a low dose of l-[1-13C]valine and isotope ratio mass spectrometry.
Analytical biochemistry 1998;265(2):308-12.
1998: NR Koopen; Michael Müller; roel vonk; P Zimniak; Folkert Kuipers
Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation.
Biochimica et biophysica acta 1998;1408(1):1-17.
1998: Peter J Voshol; Rick Havinga; Henk Wolters; Roelof Ottenhoff; Hans M G Princen; Ronald P J Oude Elferink; Albert K Groen; Folkert Kuipers
Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Gastroenterology 1998;114(5):1024-34.
1998: NR Koopen; Henk Wolters; Rick Havinga; roel vonk; Peter L M Jansen; Michael Müller; Folkert Kuipers
Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.
Hepatology (Baltimore, Md.) 1998;27(2):537-45.
1998: Robert H J Bandsma; Frans Stellaard; roel vonk; G T Nagel; Richard A Neese; Marc K Hellerstein; Folkert Kuipers
Contribution of newly synthesized cholesterol to rat plasma and bile determined by mass isotopomer distribution analysis: bile-salt flux promotes secretion of newly synthesized cholesterol into bile.
The Biochemical journal 1998;329 ( Pt 3)():699-703.
1997: Folkert Kuipers; MC Jong; Y Lin; M Eck; Rick Havinga; Vincent Bloks; Henkjan J Verkade; Marten H Hofker; Han Moshage; TJ Berkel; R J Vonk; Louis M Havekes
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes.
The Journal of clinical investigation 1997;100(11):2915-22.
1997: NR Koopen; Henk Wolters; Michael Müller; IJ Schippers; Rick Havinga; Han Roelofsen; roel vonk; Bruno Stieger; Peter Meier; Folkert Kuipers
Hepatic bile salt flux does not modulate level and activity of the sinusoidal Na+-taurocholate cotransporter (ntcp) in rats.
Journal of hepatology 1997;27(4):699-706.
1997: Martijn Dijkstra; Folkert Kuipers; G J van den Berg; Rick Havinga; roel vonk
Differences in hepatic processing of dietary and intravenously administered copper in rats.
Hepatology (Baltimore, Md.) 1997;26(4):962-6.
1997: TA Vos; A S Gouw; Pieter A Klok; Rick Havinga; Harry van Goor; S Huitema; Han Roelofsen; Folkert Kuipers; Peter L M Jansen; Han Moshage
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.
Gastroenterology 1997;113(4):1323-33.
1997: IJ Schippers; Han Moshage; Han Roelofsen; Michael Müller; H S Heymans; Marcel H J Ruiters; Folkert Kuipers
Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation.
Cell biology and toxicology 1997;13(4-5):375-86.
1997: Han Roelofsen; TA Vos; IJ Schippers; Folkert Kuipers; H Koning; Han Moshage; Peter L M Jansen; Michael Müller
Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells.
Gastroenterology 1997;112(2):511-21.
1997: Folkert Kuipers; R P Oude Elferink; H J Verkade; Albert K Groen
Mechanisms and (patho)physiological significance of biliary cholesterol secretion.
Sub-cellular biochemistry 1997;28():295-318.
1997: Henkjan J Verkade; Folkert Kuipers; Nicole Domingo; Rick Havinga; J Léonardi; roel vonk; Huguette Lafont
Biliary secretion of anionic polypeptide fraction is not coupled to that of phospholipids and cholesterol in rats.
Hepatology (Baltimore, Md.) 1997;25(1):38-47.
1996: Henkjan J Verkade; M A de Bruijn; M A Brink; H Talsma; roel vonk; Folkert Kuipers; Albert K Groen
Interactions between organic anions, micelles and vesicles in model bile systems.
The Biochemical journal 1996;320 ( Pt 3)():917-23.
1996: M Dijkstra; G J van den Berg; Henk Wolters; G In't Veld; Maarten J H Slooff; H S Heymans; Folkert Kuipers; roel vonk
Adenosine triphosphate-dependent copper transport in human liver.
Journal of hepatology 1996;25(1):37-42.
1996: Folkert Kuipers; J M van Ree; M H Hofker; Henk Wolters; G In't Veld; Rick Havinga; roel vonk; Hans M G Princen; L M Havekes
Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver.
Hepatology (Baltimore, Md.) 1996;24(1):241-7.
1996: Y Lin; Rick Havinga; I J Schippers; Henkjan J Verkade; roel vonk; Folkert Kuipers
Characterization of the inhibitory effects of bile acids on very-low-density lipoprotein secretion by rat hepatocytes in primary culture.
The Biochemical journal 1996;316 ( Pt 2)():531-8.
1996: G J Beukeveld; G In 't Veld; Rick Havinga; Albert K Groen; BG Wolthers; Folkert Kuipers
Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport.
Journal of hepatology 1996;24(3):343-52.
1996: Y Lin; Rick Havinga; Henkjan J Verkade; Han Moshage; Maarten J H Slooff; roel vonk; Folkert Kuipers
Bile acids suppress the secretion of very-low-density lipoprotein by human hepatocytes in primary culture.
Hepatology (Baltimore, Md.) 1996;23(2):218-28.
1996: M Dijkstra; roel vonk; Folkert Kuipers
How does copper get into bile? New insights into the mechanism(s) of hepatobiliary copper transport.
Journal of hepatology 1996;24 Suppl 1():109-20.
1996: M Dijkstra; Rick Havinga; roel vonk; Folkert Kuipers
Bile secretion of cadmium, silver, zinc and copper in the rat. Involvement of various transport systems.
Life sciences 1996;59(15):1237-46.
1995: G J Beukeveld; C M Bijleveld; Folkert Kuipers; HG Kreeftenberg; JR Huizenga; K te Velde; BG Wolthers
Evaluation and clinical application of the Enterotest for the determination of human biliary porphyrin composition.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1995;33(7):453-62.
1995: Y Lin; M J Smit; Rick Havinga; Henkjan J Verkade; roel vonk; Folkert Kuipers
Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat hepatocytes.
Biochimica et biophysica acta 1995;1256(1):88-96.
1995: Henkjan J Verkade; roel vonk; Folkert Kuipers
New insights into the mechanism of bile acid-induced biliary lipid secretion.
Hepatology (Baltimore, Md.) 1995;21(4):1174-89.
1995: M Dijkstra; G In 't Veld; G J van den Berg; M Müller; Folkert Kuipers; roel vonk
Adenosine triphosphate-dependent copper transport in isolated rat liver plasma membranes.
The Journal of clinical investigation 1995;95(1):412-6.
1994: M J Smit; Henkjan J Verkade; Rick Havinga; roel vonk; Gerrit L Scherphof; G In 't Veld; Folkert Kuipers
Dietary fish oil potentiates bile acid-induced cholesterol secretion into bile in rats.
Journal of lipid research 1994;35(2):301-10.
1994: M J Smit; Henk Wolters; A M Temmerman; Folkert Kuipers; A C Beynen; roel vonk
Effects of dietary corn and olive oil versus coconut fat on biliary cholesterol secretion in rats.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1994;64(1):75-80.
1993: Henkjan J Verkade; Henk Wolters; A Gerding; Rick Havinga; Vaclav Fidler; roel vonk; Folkert Kuipers
Mechanism of biliary lipid secretion in the rat: a role for bile acid-independent bile flow?
Hepatology (Baltimore, Md.) 1993;17(6):1074-80.
1993: M Dijkstra; Folkert Kuipers; E P Smit; Rick Havinga; roel vonk
The role of glutathione in bile secretion of endogenous trace elements in rats.
The Journal of laboratory and clinical medicine 1993;121(6):751-8.
1993: Henkjan J Verkade; Rick Havinga; A Gerding; roel vonk; Folkert Kuipers
Mechanism of bile acid-induced biliary lipid secretion in the rat: effect of conjugated bilirubin.
The American journal of physiology 1993;264(3 Pt 1):G462-9.
1993: M J Smit; Folkert Kuipers; roel vonk; A M Temmerman; S Jäckle; Eberhard Windler
Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat.
Hepatology (Baltimore, Md.) 1993;17(3):445-54.
1992: Henk Wolters; Folkert Kuipers; Maarten J H Slooff; roel vonk
Adenosine triphosphate-dependent taurocholate transport in human liver plasma membranes.
The Journal of clinical investigation 1992;90(6):2321-6.
1992: Henkjan J Verkade; K J Zaal; J T Derksen; roel vonk; Dick Hoekstra; Folkert Kuipers; Gerrit L Scherphof
Processing of the phospholipid analogue phosphatidyl(N-sulphorhodamine B sulphonyl)ethanolamine by rat hepatocytes in vitro and in vivo.
The Biochemical journal 1992;284 ( Pt 1)():259-65.
1992: Folkert Kuipers; M J Hardonk; roel vonk; R van der Meer
Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats.
The American journal of physiology 1992;262(2 Pt 1):G267-73.
1991: Henk Wolters; M Spiering; A Gerding; Maarten J H Slooff; Folkert Kuipers; M J Hardonk; roel vonk
Isolation and characterization of canalicular and basolateral plasma membrane fractions from human liver.
Biochimica et biophysica acta 1991;1069(1):61-9.
1991: M J Smit; A M Temmerman; Henk Wolters; Folkert Kuipers; A C Beynen; roel vonk
Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats.
The Journal of clinical investigation 1991;88(3):943-51.
1991: M Dijkstra; Folkert Kuipers; E P Smit; J J de Vries; Rick Havinga; roel vonk
Biliary secretion of trace elements and minerals in the rat. Effects of bile flow variation and diurnal rhythms.
Journal of hepatology 1991;13(1):112-9.
1991: Henkjan J Verkade; J T Derksen; A Gerding; Gerrit L Scherphof; roel vonk; Folkert Kuipers
Differential hepatic processing and biliary secretion of head-group and acyl chains of liposomal phosphatidylcholines.
The Biochemical journal 1991;275 ( Pt 1)():139-44.
1991: Ronald P J Oude Elferink; Roelof Ottenhoff; A Radominska; Alan F Hofmann; Folkert Kuipers; Peter L M Jansen
Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions.
The Biochemical journal 1991;274 ( Pt 1)():281-6.
1990: Henkjan J Verkade; M J Wolbers; Rick Havinga; D R Uges; roel vonk; Folkert Kuipers
The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat.
Gastroenterology 1990;99(5):1485-92.
1990: M Dijkstra; Folkert Kuipers; Rick Havinga; E P Smit; roel vonk
Bile secretion of trace elements in rats with a congenital defect in hepatobiliary transport of glutathione.
Pediatric research 1990;28(4):339-43.
1990: M J Smit; A M Temmerman; Rick Havinga; Folkert Kuipers; roel vonk
Short- and long-term effects of biliary drainage on hepatic cholesterol metabolism in the rat.
The Biochemical journal 1990;269(3):781-8.
1990: H F Bakkeren; Folkert Kuipers; roel vonk; Theo Van berkel
Evidence for reverse cholesterol transport in vivo from liver endothelial cells to parenchymal cells and bile by high-density lipoprotein.
The Biochemical journal 1990;268(3):685-91.
1990: R Houwen; M Dijkstra; Folkert Kuipers; E P Smit; Rick Havinga; roel vonk
Two pathways for biliary copper excretion in the rat. The role of glutathione.
Biochemical pharmacology 1990;39(6):1039-44.
1989: Folkert Kuipers; A Radominska; Piotr Zimniak; J M Little; Rick Havinga; roel vonk; R Lester
Defective biliary secretion of bile acid 3-O-glucuronides in rats with hereditary conjugated hyperbilirubinemia.
Journal of lipid research 1989;30(12):1835-45.
1989: Folkert Kuipers; Rick Havinga; C M Huijsmans; roel vonk; H M Princen
Inhibition and induction of bile acid synthesis by ketoconazole. Effects on bile formation in the rat.
Lipids 1989;24(9):759-64.
1989: C M A Bijleveld; roel vonk; Folkert Kuipers; Rick Havinga; Renze Boverhof; B J Koopman; BG Wolthers; J Fernandes
Benign recurrent intrahepatic cholestasis: altered bile acid metabolism.
Gastroenterology 1989;97(2):427-32.
1989: M Polhuijs; Folkert Kuipers; R J Vonk; Gerard J Mulder
Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
The Journal of pharmacology and experimental therapeutics 1989;249(3):874-8.
1989: Folkert Kuipers; J Fred Nagelkerke; H Bakkeren; Rick Havinga; Theo Van berkel; roel vonk
Processing of cholesteryl ester from low-density lipoproteins in the rat. Hepatic metabolism and biliary secretion after uptake by different hepatic cell types.
The Biochemical journal 1989;257(3):699-704.
1988: B J Koopman; Folkert Kuipers; C M A Bijleveld; J C van der Molen; G T Nagel; roel vonk; BG Wolthers
Determination of cholic acid and chenodeoxycholic acid pool sizes and fractional turnover rates by means of stable isotope dilution technique, making use of deuterated cholic acid and chenodeoxycholic acid.
Clinica chimica acta; international journal of clinical chemistry 1988;175(2):143-55.
1988: Folkert Kuipers; M Enserink; Rick Havinga; A B van der Steen; M J Hardonk; J Fevery; roel vonk
Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat.
The Journal of clinical investigation 1988;81(5):1593-9.
1988: Theo Van berkel; Folkert Kuipers; J Fred Nagelkerke; H F Bakkeren; Rick Havinga; roel vonk
Processing of cholesteryl ester from low density lipoproteins in the rat: hepatic metabolism and biliary excretion after uptake by different hepatic cells.
Agents and actions. Supplements 1988;26():99-107.
1987: Gerrit L Scherphof; Folkert Kuipers; J T Derksen; H H Spanjer; roel vonk
Liposomes in vivo; conversion of liposomal cholesterol to bile salts.
Biochemical Society transactions 1987;15 Suppl():62S-68S.
1987: Folkert Kuipers; J P Derksen; A Gerding; Gerrit L Scherphof; roel vonk
Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid.
Biochimica et biophysica acta 1987;922(2):136-44.
1987: Gerrit L Scherphof; H H Spanjer; J T Derksen; Folkert Kuipers; roel vonk; Toos Daemen; F H Roerdink
Delivery of liposome-associated drugs to liver cells.
Biochemical Society transactions 1987;15(3):345-8.
1986: J Fred Nagelkerke; H F Bakkeren; Folkert Kuipers; roel vonk; Theo Van berkel
Hepatic processing of the cholesteryl ester from low density lipoprotein in the rat.
The Journal of biological chemistry 1986;261(19):8908-13.
1986: Folkert Kuipers; H H Spanjer; Rick Havinga; Gerrit L Scherphof; roel vonk
Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids.
Biochimica et biophysica acta 1986;876(3):559-66.