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Folkert Kuipers

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
78
Havinga, Rick
55
Vonk, Roel
43
Verkade, Henkjan
33
Bloks, Vincent
28
Stellaard, Frans
27
Wolters, Henk
26
Staels, Bart
25
Groen, Albert
22
Romijn, Johannes
21
Havekes, Louis
19
Reijngoud, Dirk-Jan
17
Jansen, Peter
16
Voshol, Peter
15
Müller, Michael
15
Baller, Julius

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Publications

TOP 3
Wiersma Harmen; Gatti Alberto; Nijstad Niels; Oude Elferink Ronald P J; Kuipers Folkert; Tietge Uwe J F
Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.
Schreurs M; van Dijk T H; Gerding A; Havinga R; Reijngoud D-J; Kuipers F
Soraphen, an inhibitor of the acetyl-CoA carboxylase system, improves peripheral insulin sensitivity in mice fed a high-fat diet.
Wiersma Harmen; Nijstad Niels; de Boer Jan Freark; Out Ruud; Hogewerf Wytse; Van Berkel Theo J; Kuipers Folkert; Tietge Uwe J F
Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet.

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All Publications

2009: Wiersma Harmen; Gatti Alberto; Nijstad Niels; Oude Elferink Ronald P J; Kuipers Folkert; Tietge Uwe J F
Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.
Hepatology (Baltimore, Md.) 2009;50(4):1263-72.
2009: Schreurs M; van Dijk T H; Gerding A; Havinga R; Reijngoud D-J; Kuipers F
Soraphen, an inhibitor of the acetyl-CoA carboxylase system, improves peripheral insulin sensitivity in mice fed a high-fat diet.
Diabetes, obesity & metabolism 2009;11(10):987-91.
2009: Wiersma Harmen; Nijstad Niels; de Boer Jan Freark; Out Ruud; Hogewerf Wytse; Van Berkel Theo J; Kuipers Folkert; Tietge Uwe J F
Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet.
Atherosclerosis 2009;206(1):141-7.
2009: Wiersma Harmen; Gatti Alberto; Nijstad Niels; Kuipers Folkert; Tietge Uwe J F
Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice.
Journal of lipid research 2009;50(8):1571-80.
2009: van der Veen Jelske N; van Dijk Theo H; Vrins Carlos L J; van Meer Hester; Havinga Rick; Bijsterveld Klaas; Tietge Uwe J F; Groen Albert K; Kuipers Folkert
Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.
The Journal of biological chemistry 2009;284(29):19211-9.
2009: de Jonge-Peeters Susan D P W M; van der Weide Karen; Kuipers Folkert; Sluiter Wim J; de Vries Elisabeth G E; Vellenga Edo
Variability in responsiveness to lovastatin of the primitive CD34+ AML subfraction compared to normal CD34+ cells.
Annals of hematology 2009;88(6):573-80.
2009: van der Weide Karen; de Jonge-Peeters Susan D P W M; Kuipers Folkert; de Vries Elisabeth G E; Vellenga Edo
Combining simvastatin with the farnesyltransferase inhibitor tipifarnib results in an enhanced cytotoxic effect in a subset of primary CD34+ acute myeloid leukemia samples.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(9):3076-83.
2009: Le May Cédric; Kourimate Sanae; Langhi Cédric; Chétiveaux Maud; Jarry Anne; Comera Christine; Collet Xavier; Kuipers Folkert; Krempf Michel; Cariou Bertrand; Costet Philippe
Proprotein convertase subtilisin kexin type 9 null mice are protected from postprandial triglyceridemia.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(5):684-90.
2009: van Dijk Theo H; Grefhorst Aldo; Oosterveer Maaike H; Bloks Vincent W; Staels Bart; Reijngoud Dirk-Jan; Kuipers Folkert
An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice.
The Journal of biological chemistry 2009;284(16):10315-23.
2009: Windler Eberhard; Zyriax Birgit-Christiane; Kuipers Folkert; Linseisen Jakob; Boeing Heiner
Association of plasma phytosterol concentrations with incident coronary heart disease Data from the CORA study, a case-control study of coronary artery disease in women.
Atherosclerosis 2009;203(1):284-90.
2009: Lefebvre Philippe; Cariou Bertrand; Lien Fleur; Kuipers Folkert; Staels Bart
Role of bile acids and bile acid receptors in metabolic regulation.
Physiological reviews 2009;89(1):147-91.
2009: Hoeke Martijn O; Plass Jacqueline R M; Heegsma Janette; Geuken Mariska; van Rijsbergen Duncan; Baller Julius F W; Kuipers Folkert; Moshage Han; Jansen Peter L M; Faber Klaas Nico
Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
Hepatology (Baltimore, Md.) 2009;49(1):151-9.
2009: Buis Carlijn I; Geuken Erwin; Visser Dorien S; Kuipers Folkert; Haagsma Elizabeth B; Verkade Henkjan J; Porte Robert J
Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures.
Journal of hepatology 2009;50(1):69-79.
2009: Oosterveer Maaike H; van Dijk Theo H; Tietge Uwe J F; Boer Theo; Havinga Rick; Stellaard Frans; Groen Albert K; Kuipers Folkert; Reijngoud Dirk-Jan
High fat feeding induces hepatic fatty acid elongation in mice.
PloS one 2009;4(6):e6066.
2009: Mulder Jaap; Karpen Saul J; Tietge Uwe J F; Kuipers Folkert
Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.
Frontiers in bioscience : a journal and virtual library 2009;14():2599-630.
2008: Oosterveer Maaike H; van Dijk Theo H; Grefhorst Aldo; Bloks Vincent W; Havinga Rick; Kuipers Folkert; Reijngoud Dirk-Jan
Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice.
The Journal of biological chemistry 2008;283(37):25437-45.
2008: Duez Hélène; van der Veen Jelske N; Duhem Christian; Pourcet Benoît; Touvier Thierry; Fontaine Coralie; Derudas Bruno; Baugé Eric; Havinga Rick; Bloks Vincent W; Wolters Henk; van der Sluijs Fjodor H; Vennström Björn; Kuipers Folkert; Staels Bart
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
Gastroenterology 2008;135(2):689-98.
2008: Kuipers Folkert; Groen Albert K
Chipping away at gallstones.
Nature medicine 2008;14(7):715-6.
2008: van der Velde Astrid E; Vrins Carlos L J; van den Oever Karin; Seemann Ingar; Oude Elferink Ronald P J; van Eck Miranda; Kuipers Folkert; Groen Albert K
Regulation of direct transintestinal cholesterol excretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(1):G203-G208.
2008: Bandsma Robert H J; Prinsen Berthil H; van Der Velden Monique de Sain; Rake Jan-Peter; Boer Theo; Smit G Peter A; Reijngoud Dirk-Jan; Kuipers Folkert
Increased de novo lipogenesis and delayed conversion of large VLDL into intermediate density lipoprotein particles contribute to hyperlipidemia in glycogen storage disease type 1a.
Pediatric research 2008;63(6):702-7.
2008: Herrema Hilde; Derks Terry G J; van Dijk Theo H; Bloks Vincent W; Gerding Albert; Havinga Rick; Tietge Uwe J F; Müller Michael; Smit G Peter A; Kuipers Folkert; Reijngoud Dirk-Jan
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.
Hepatology (Baltimore, Md.) 2008;47(6):1894-904.
2008: de Vogel-van den Bosch Heleen M; de Wit Nicole J W; Hooiveld Guido J E J; Vermeulen Hanneke; van der Veen Jelske N; Houten Sander M; Kuipers Folkert; Müller Michael; van der Meer Roelof
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(5):G1171-80.
2008: Liu Yan; Havinga Rick; VAN DER Leij Feike R; Boverhof Renze; Sauer Pieter J J; Kuipers Folkert; Stellaard Frans
Dexamethasone exposure of neonatal rats modulates biliary lipid secretion and hepatic expression of genes controlling bile acid metabolism in adulthood without interfering with primary bile acid kinetics.
Pediatric research 2008;63(4):375-81.
2008: Liu Yan; van Goor Harry; Havinga Rick; Baller Julius F W; Bloks Vincent W; van der Leij Feike R; Sauer Pieter J J; Kuipers Folkert; Navis Gerjan; de Borst Martin H
Neonatal dexamethasone administration causes progressive renal damage due to induction of an early inflammatory response.
American journal of physiology. Renal physiology 2008;294(4):F768-76.
2008: Abildayeva Karlygash; Berbée Jimmy F P; Blokland Arjan; Jansen Paula J; Hoek Frans J; Meijer Onno; Lütjohann Dieter; Gautier Thomas; Pillot Thierry; De Vente Jan; Havekes Louis M; Ramaekers Frans C S; Kuipers Folkert; Rensen Patrick C N; Mulder Monique
Human apolipoprotein C-I expression in mice impairs learning and memory functions.
Journal of lipid research 2008;49(4):856-69.
2008: Derks Terry G J; van Dijk Theo H; Grefhorst Aldo; Rake Jan-Peter; Smit G Peter A; Kuipers Folkert; Reijngoud Dirk-Jan
Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice.
Hepatology (Baltimore, Md.) 2008;47(3):1032-42.
2008: Hofker Marten; Bernini Franco; von Eckardstein Arnold; Freeman Dilys; Heeren Joerg; Karpe Fredrik; Kalopissis Athina; Kronenberg Florian; Kuipers Folkert; Lindstedt Ken; Parini Paolo; Schuster Gertrud; van Dijk Ko Willems
European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.
Atherosclerosis 2008;197(1):471-9.
2008: Kruit Janine K; Drayer A Lyndsay; Bloks Vincent W; Blom Nel; Olthof Sandra G; Sauer Pieter J J; de Haan Gerald; Kema Ido P; Vellenga Edo; Kuipers Folkert
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.
The Journal of biological chemistry 2008;283(10):6281-7.
2008: Tietge Uwe J F; Nijstad Niels; Havinga Rick; Baller Julius F W; van der Sluijs Fjodor H; Bloks Vincent W; Gautier Thomas; Kuipers Folkert
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Journal of lipid research 2008;49(3):563-71.
2007: van der Leij Feike R; Bloks Vincent W; Grefhorst Aldo; Hoekstra Jildou; Gerding Albert; Kooi Krista; Gerbens Frans; te Meerman Gerard; Kuipers Folkert
Gene expression profiling in livers of mice after acute inhibition of beta-oxidation.
Genomics 2007;90(6):680-9.
2007: Cariou Bertrand; Bouchaert Emmanuel; Abdelkarim Mouaadh; Dumont Julie; Caron Sandrine; Fruchart Jean-Charles; Burcelin Rémy; Kuipers Folkert; Staels Bart
FXR-deficiency confers increased susceptibility to torpor.
FEBS letters 2007;581(27):5191-8.
2007: van der Velde Astrid E; Vrins Carlos L J; van den Oever Karin; Kunne Cindy; Oude Elferink Ronald P J; Kuipers Folkert; Groen Albert K
Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice.
Gastroenterology 2007;133(3):967-75.
2007: Los E Leonie; Wolters Henk; Stellaard Frans; Kuipers Folkert; Verkade Henkjan J; Rings Edmond H H M
Intestinal capacity to digest and absorb carbohydrates is maintained in a rat model of cholestasis.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(3):G615-22.
2007: Verkade Henkjan J; Havinga Rick; Shields David J; Wolters Henk; Bloks Vincent W; Kuipers Folkert; Vance Dennis E; Agellon Luis B
The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion.
Journal of lipid research 2007;48(9):2058-64.
2007: Hofker Marten; Calabresi Laura; von Eckardstein Arnold; Heeren Joerg; Karpe Fredrik; Kalopissis Athina; Kronenberg Florian; Kuipers Folkert; Lindstedt Ken; Parini Paolo; Schuster Gertrud; van Dijk Ko Willems
European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.
Atherosclerosis 2007;193(2):461-8.
2007: Gooijert Karin E R; Havinga Rick; Oosterloo-Duinkerken Alida R; Venekamp-Hoolsema Enge E A; Kuipers Folkert; Verkade Henkjan J
Stimulation of fecal fat excretion and the disposal of protoporphyrin in a murine model for erythropoietic protoporphyria.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(2):G510-6.
2007: Herrema Hilde; Smit G Peter A; Reijngoud Dirk-Jan; Kuipers Folkert
Does increased fatty acid oxidation enhance development of liver cirrhosis and progression to hepatocellular carcinoma in patients with glycogen storage disease type-III?
Journal of hepatology 2007;47(2):298-300; author reply 300-1.
2007: Plösch T; van Straten E M E; Kuipers F
Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?
Placenta 2007;28(7):604-10.
2007: Attie Alan D; Flowers Matthew T; Flowers Jessica B; Groen Albert K; Kuipers Folkert; Ntambi James M
Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes.
Nutrition reviews 2007;65(6 Pt 2):S35-8.
2007: Kuipers Folkert; Stroeve Johanna H M; Caron Sandrine; Staels Bart
Bile acids, farnesoid X receptor, atherosclerosis and metabolic control.
Current opinion in lipidology 2007;18(3):289-97.
2007: de Jonge-Peeters Susan D P W M; Kuipers Folkert; de Vries Elisabeth G E; Vellenga Edo
ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance.
Critical reviews in oncology/hematology 2007;62(3):214-26.
2007: Aerts Johannes M; Ottenhoff Roelof; Powlson Andrew S; Grefhorst Aldo; van Eijk Marco; Dubbelhuis Peter F; Aten Jan; Kuipers Folkert; Serlie Mireille J; Wennekes Tom; Sethi Jaswinder K; O'Rahilly Stephen; Overkleeft Hermen S
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Diabetes 2007;56(5):1341-9.
2007: Nohara Atsushi; Kawashiri Masa-aki; Claudel Thierry; Mizuno Mihoko; Tsuchida Masayuki; Takata Mutsuko; Katsuda Shoji; Miwa Kenji; Inazu Akihiro; Kuipers Folkert; Kobayashi Junji; Koizumi Junji; Yamagishi Masakazu; Mabuchi Hiroshi
High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):923-8.
2007: Liu Yan; Havinga Rick; Bloks Vincent W; Baller Juul F; van der Leij Feike R; Reijngoud Dirk-Jan; Sauer Pieter J J; Kuipers Folkert
Postnatal treatment with dexamethasone perturbs hepatic and cardiac energy metabolism and is associated with a sustained atherogenic plasma lipid profile in suckling rats.
Pediatric research 2007;61(2):165-70.
2007: van der Veen Jelske N; Havinga Rick; Bloks Vincent W; Groen Albert K; Kuipers Folkert
Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha.
Journal of lipid research 2007;48(2):337-47.
2007: Ghose Romi; Mulder Jaap; von Furstenberg Richard J; Thevananther Sundararajah; Kuipers Folkert; Karpen Saul J
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.
Journal of hepatology 2007;46(1):115-23.
2007: Gautier Thomas; Tietge Uwe J F; Boverhof Renze; Perton Frank G; Le Guern Naig; Masson David; Rensen Patrick C N; Havekes Louis M; Lagrost Laurent; Kuipers Folkert
Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein.
Journal of lipid research 2007;48(1):30-40.
2007: Attie Alan D; Flowers Matthew T; Flowers Jessica B; Groen Albert K; Kuipers Folkert; Ntambi James M
Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes.
Novartis Foundation symposium 2007;286():47-53; discussion 54-7, 162-3, 196-203.
2007: Staels Bart; Kuipers Folkert
Bile acid sequestrants and the treatment of type 2 diabetes mellitus.
Drugs 2007;67(10):1383-92.
2006: Lalloyer Fanny; Fiévet Catherine; Lestavel Sophie; Torpier Gérard; van der Veen Jelske; Touche Véronique; Bultel Stéphanie; Yous Saïd; Kuipers Folkert; Paumelle Réjane; Fruchart Jean-Charles; Staels Bart; Tailleux Anne
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2731-7.
2006: Korsheninnikova E; van der Zon G C M; Voshol P J; Janssen G M; Havekes L M; Grefhorst A; Kuipers F; Reijngoud D-J; Romijn J A; Ouwens D M; Maassen J A
Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice.
Diabetologia 2006;49(12):3049-57.
2006: Flowers Matthew T; Groen Albert K; Oler Angie Tebon; Keller Mark P; Choi Younjeong; Schueler Kathryn L; Richards Oliver C; Lan Hong; Miyazaki Makoto; Kuipers Folkert; Kendziorski Christina M; Ntambi James M; Attie Alan D
Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.
Journal of lipid research 2006;47(12):2668-80.
2006: den Boer Marion A M; Voshol Peter J; Kuipers Folkert; Romijn Johannes A; Havekes Louis M
Hepatic glucose production is more sensitive to insulin-mediated inhibition than hepatic VLDL-triglyceride production.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1360-4.
2006: Kruit Janine-K; Groen Albert K; van Berkel Theo J; Kuipers Folkert
Emerging roles of the intestine in control of cholesterol metabolism.
World journal of gastroenterology : WJG 2006;12(40):6429-39.
2006: Out Ruud; Hoekstra Menno; Hildebrand Reeni B; Kruit Janine K; Meurs Illiana; Li Zhaosha; Kuipers Folkert; Van Berkel Theo J C; Van Eck Miranda
Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2295-300.
2006: den Boer Marion A M; Voshol Peter J; Schröder-van der Elst Janny P; Korsheninnikova Elena; Ouwens D Margriet; Kuipers Folkert; Havekes Louis M; Romijn Johannes A
Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice.
Endocrinology 2006;147(10):4553-8.
2006: Brunham Liam R; Kruit Janine K; Pape Terry D; Parks John S; Kuipers Folkert; Hayden Michael R
Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.
Circulation research 2006;99(7):672-4.
2006: Plösch Torsten; van der Veen Jelske N; Havinga Rick; Huijkman Nicolette C A; Bloks Vincent W; Kuipers Folkert
Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G414-23.
2006: Plösch Torsten; Kruit Janine K; Bloks Vincent W; Huijkman Nicolette C A; Havinga Rick; Duchateau Guus S M J E; Lin Yuguang; Kuipers Folkert
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter.
The Journal of nutrition 2006;136(8):2135-40.
2006: Lalloyer Fanny; Vandewalle Brigitte; Percevault Frédéric; Torpier Gérard; Kerr-Conte Julie; Oosterveer Maaike; Paumelle Réjane; Fruchart Jean-Charles; Kuipers Folkert; Pattou François; Fiévet Catherine; Staels Bart
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Diabetes 2006;55(6):1605-13.
2006: Werner Anniek; Havinga Rick; Perton Frank; Kuipers Folkert; Verkade Henkjan J
Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1177-85.
2006: Peeters Susan D P W M; van der Kolk Dorina M; de Haan Gerald; Bystrykh Leonid; Kuipers Folkert; de Vries Elisabeth G E; Vellenga Edo
Selective expression of cholesterol metabolism genes in normal CD34+CD38- cells with a heterogeneous expression pattern in AML cells.
Experimental hematology 2006;34(5):622-30.
2006: Abildayeva Karlygash; Jansen Paula J; Hirsch-Reinshagen Veronica; Bloks Vincent W; Bakker Arjen H F; Ramaekers Frans C S; de Vente Jan; Groen Albert K; Wellington Cheryl L; Kuipers Folkert; Mulder Monique
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.
The Journal of biological chemistry 2006;281(18):12799-808.
2006: Jansen Paula J; Lütjohann Dieter; Abildayeva Karlygash; Vanmierlo Tim; Plösch Torsten; Plat Jogchum; von Bergmann Klaus; Groen Albert K; Ramaekers Frans C S; Kuipers Folkert; Mulder Monique
Dietary plant sterols accumulate in the brain.
Biochimica et biophysica acta 2006;1761(4):445-53.
2006: Jonkers Iris J A M; Smelt Augustinus H M; Princen Hans M G; Kuipers Folkert; Romijn Johannes A; Boverhof Renze; Masclee Ad A M; Stellaard Frans
Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.
The Journal of nutrition 2006;136(4):987-91.
2006: Brunham Liam R; Kruit Janine K; Iqbal Jahangir; Fievet Catherine; Timmins Jenelle M; Pape Terry D; Coburn Bryan A; Bissada Nagat; Staels Bart; Groen Albert K; Hussain M Mahmood; Parks John S; Kuipers Folkert; Hayden Michael R
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
The Journal of clinical investigation 2006;116(4):1052-62.
2006: Cariou Bertrand; van Harmelen Kirsten; Duran-Sandoval Daniel; van Dijk Theo H; Grefhorst Aldo; Abdelkarim Mouaadh; Caron Sandrine; Torpier Gérard; Fruchart Jean-Charles; Gonzalez Frank J; Kuipers Folkert; Staels Bart
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
The Journal of biological chemistry 2006;281(16):11039-49.
2006: Mandard Stéphane; Zandbergen Fokko; van Straten Esther; Wahli Walter; Kuipers Folkert; Müller Michael; Kersten Sander
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
The Journal of biological chemistry 2006;281(2):934-44.
2006: den Boer Marion A M; Berbée Jimmy F P; Reiss Peter; van der Valk Marc; Voshol Peter J; Kuipers Folkert; Havekes Louis M; Rensen Patrick C N; Romijn Johannes A
Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):124-9.
2005: van Dijk Gertjan; de Vries Koert; Nyakas Csaba; Buwalda Bauke; Adage Tiziana; Kuipers Folkert; Kas Martien J H; Adan Roger A H; Wilkinson Charles W; Thiele Todd E; Scheurink Anton J W
Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.
Endocrinology 2005;146(12):5247-56.
2005: Meurs Illiana; Hoekstra Menno; van Wanrooij Eva J A; Hildebrand Reeni B; Kuiper Johan; Kuipers Folkert; Hardeman Max R; Van Berkel Theo J C; Van Eck Miranda
HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes.
Experimental hematology 2005;33(11):1309-19.
2005: Geuken Erwin; Visser Dorien S; Leuvenink Henri G D; de Jong Koert P; Peeters Paul M J G; Slooff Maarten J H; Kuipers Folkert; Porte Robert J
Hepatic expression of ABC transporters G5 and G8 does not correlate with biliary cholesterol secretion in liver transplant patients.
Hepatology (Baltimore, Md.) 2005;42(5):1166-74.
2005: Grefhorst Aldo; van Dijk Theo H; Hammer Anke; van der Sluijs Fjodor H; Havinga Rick; Havekes Louis M; Romijn Johannes A; Groot Pieter H; Reijngoud Dirk-Jan; Kuipers Folkert
Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.
American journal of physiology. Endocrinology and metabolism 2005;289(5):E829-38.
2005: Claudel Thierry; Staels Bart; Kuipers Folkert
The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(10):2020-30.
2005: Goudriaan Jeltje R; den Boer Marion A M; Rensen Patrick C N; Febbraio Maria; Kuipers Folkert; Romijn Johannes A; Havekes Louis M; Voshol Peter J
CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance.
Journal of lipid research 2005;46(10):2175-81.
2005: Grefhorst Aldo; Hoekstra Jildou; Derks Terry G J; Ouwens D Margriet; Baller Julius F W; Havinga Rick; Havekes Louis M; Romijn Johannes A; Kuipers Folkert
Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(3):G592-8.
2005: Cariou Bertrand; van Harmelen Kirsten; Duran-Sandoval Daniel; van Dijk Theo; Grefhorst Aldo; Bouchaert Emmanuel; Fruchart Jean-Charles; Gonzalez Frank J; Kuipers Folkert; Staels Bart
Transient impairment of the adaptive response to fasting in FXR-deficient mice.
FEBS letters 2005;579(19):4076-80.
2005: Duran-Sandoval Daniel; Cariou Bertrand; Percevault Fredéric; Hennuyer Nathalie; Grefhorst Aldo; van Dijk Theo H; Gonzalez Frank J; Fruchart Jean-Charles; Kuipers Folkert; Staels Bart
The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.
The Journal of biological chemistry 2005;280(33):29971-9.
2005: Stellaard Frans; Kuipers Folkert
Assessment of modes of action and efficacy of plasma cholesterol-lowering drugs: measurement of cholesterol absorption, cholesterol synthesis and bile acid synthesis and turnover using novel stable isotope techniques.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(2):209-18.
2005: Hulzebos Christian V; Voshol Peter J; Wolters Henk; Kruit Janine K; Ottenhof Roelof; Groen Albert K; Stellaard Frans; Verkade Henkjan J; Kuipers Folkert
Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(3):604-12.
2005: Werner Anniek; Havinga Rick; Bos Trijnie; Bloks Vincent W; Kuipers Folkert; Verkade Henkjan J
Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(6):G1150-8.
2005: Duivenvoorden Ilse; Teusink Bas; Rensen Patrick C N; Kuipers Folkert; Romijn Johannes A; Havekes Louis M; Voshol Peter J
Acute inhibition of hepatic beta-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity.
Journal of lipid research 2005;46(5):988-93.
2005: Cariou Bertrand; Duran-Sandoval Daniel; Kuipers Folkert; Staels Bart
Farnesoid X receptor: a new player in glucose metabolism?
Endocrinology 2005;146(3):981-3.
2005: Yan Xuedong; Kuipers Folkert; Havekes Louis M; Havinga Rick; Dontje Bert; Poelstra Klaas; Scherphof Gerrit L; Kamps Jan A A M
The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse.
Biochemical and biophysical research communications 2005;328(1):57-62.
2005: van der Veen Jelske N; Kruit Janine K; Havinga Rick; Baller Julius F W; Chimini Giovanna; Lestavel Sophie; Staels Bart; Groot Pieter H E; Groen Albert K; Kuipers Folkert
Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.
Journal of lipid research 2005;46(3):526-34.
2005: Kruit Janine K; Plösch Torsten; Havinga Rick; Boverhof Renze; Groot Pieter H E; Groen Albert K; Kuipers Folkert
Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.
Gastroenterology 2005;128(1):147-56.
2005: Sturm Ekkehard; Havinga Rick; Baller Julius F W; Wolters Henk; van Rooijen Nico; Kamps Jan A A M; Verkade Henkjan J; Karpen Saul J; Kuipers Folkert
Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.
Journal of hepatology 2005;42(1):102-9.
2005: Delsing Dianne J M; Post Sabine M; Groenendijk Martine; Solaas Karianne; van der Boom Hans; van Duyvenvoorde Wim; de Wit Elly C M; Bloks Vincent W; Kuipers Folkert; Havekes Louis M; Princen Hans M G
Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice.
Journal of cardiovascular pharmacology 2005;45(1):53-60.
2005: Plösch T; Kosters A; Groen A K; Kuipers F
The ABC of hepatic and intestinal cholesterol transport.
Handbook of experimental pharmacology 2005;(170):465-82.
2004: Geuken Erwin; Visser Dorien; Kuipers Folkert; Blokzijl Hans; Leuvenink Henri G D; de Jong Koert P; Peeters Paul M J G; Jansen Peter L M; Slooff Maarten J H; Gouw Annette S H; Porte Robert J
Rapid increase of bile salt secretion is associated with bile duct injury after human liver transplantation.
Journal of hepatology 2004;41(6):1017-25.
2004: Allick Gideon; Bisschop Peter H; Ackermans Mariette T; Endert Erik; Meijer Alfred J; Kuipers Folkert; Sauerwein Hans P; Romijn Johannes A
A low-carbohydrate/high-fat diet improves glucoregulation in type 2 diabetes mellitus by reducing postabsorptive glycogenolysis.
The Journal of clinical endocrinology and metabolism 2004;89(12):6193-7.
2004: Kuipers Folkert; Claudel Thierry; Sturm Ekkehard; Staels Bart
The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism.
Reviews in endocrine & metabolic disorders 2004;5(4):319-26.
2004: Bandsma R H J; Grefhorst A; van Dijk T H; van der Sluijs F H; Hammer A; Reijngoud D-J; Kuipers F
Enhanced glucose cycling and suppressed de novo synthesis of glucose-6-phosphate result in a net unchanged hepatic glucose output in ob/ob mice.
Diabetologia 2004;47(11):2022-31.
2004: Renfurm Lorraine N; Bandsma Robert H J; Verkade Henkjan J; Hulzebos Christiaan V; van Dijk Theo; Boer Theo; Stellaard Frans; Kuipers Folkert; Sauer Pieter J J
Cholesterol synthesis and de novo lipogenesis in premature infants determined by mass isotopomer distribution analysis.
Pediatric research 2004;56(4):602-7.
2004: Claudel Thierry; Sturm Ekkehard; Kuipers Folkert; Staels Bart
The farnesoid X receptor: a novel drug target?
Expert opinion on investigational drugs 2004;13(9):1135-48.
2004: Hendrikse N Harry; Kuipers Folkert; Meijer Coby; Havinga Rick; Bijleveld Charles M A; van der Graaf Winette T A; Vaalburg Willem; de Vries Elisabeth G E
In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.
Cancer chemotherapy and pharmacology 2004;54(2):131-8.
2004: Hulzebos Christian V; Bijleveld Charles M A; Stellaard Frans; Kuipers Folkert; Fidler Vaclav; Slooff Maarten J H; Peeters Paul M J G; Sauer Pieter J J; Verkade Henkjan J
Cyclosporine A-induced reduction of bile salt synthesis associated with increased plasma lipids in children after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(7):872-80.
2004: Werner Anniek; Havinga Rick; Kuipers Folkert; Verkade Henkjan J
Treatment of EFA deficiency with dietary triglycerides or phospholipids in a murine model of extrahepatic cholestasis.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(5):G822-32.
2004: Bisschop Peter H; Bandsma Robert H J; Stellaard Frans; ter Harmsel Anke; Meijer Alfred J; Sauerwein Hans P; Kuipers Folkert; Romijn Johannes A
Low-fat, high-carbohydrate and high-fat, low-carbohydrate diets decrease primary bile acid synthesis in humans.
The American journal of clinical nutrition 2004;79(4):570-6.
2004: Duran-Sandoval Daniel; Mautino Gisèle; Martin Geneviève; Percevault Fréderic; Barbier Olivier; Fruchart Jean-Charles; Kuipers Folkert; Staels Bart
Glucose regulates the expression of the farnesoid X receptor in liver.
Diabetes 2004;53(4):890-8.
2004: Mensenkamp Arjen R; Van Luyn Marja J A; Havinga Rick; Teusink Bas; Waterman Ian J; Mann Christopher J; Elzinga Baukje M; Verkade Henkjan J; Zammit Victor A; Havekes Louis M; Shoulders Carol C; Kuipers Folkert
The transport of triglycerides through the secretory pathway of hepatocytes is impaired in apolipoprotein E deficient mice.
Journal of hepatology 2004;40(4):599-606.
2004: den Boer M; Voshol P J; Kuipers F; Havekes L M; Romijn J A
Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):644-9.
2004: Ruffin Marie-Pierre; Adage Tiziana; Kuipers Folkert; Strubbe Jan H; Scheurink Anton J W; van Dijk Gertjan
Feeding and temperature responses to intravenous leptin infusion are differential predictors of obesity in rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(4):R756-63.
2004: Hofker M; Calabresi L; Jauhiainen M; Nimpf J; Rudling M; Talmud P; Mooser V; Dallinga-Thie G; von Eckardstein A; Staels B; Karpe F; Kuipers F
European Lipoprotein Club: report of the 26th ELC Annual Conference, Tutzing, 8-11 September 2003.
Atherosclerosis 2004;173(1):125-34.
2004: Nishioka Tomoji; Having Rick; Tazuma Susumu; Stellaard Frans; Kuipers Folkert; Verkade Henkjan J
Administration of phosphatidylcholine-cholesterol liposomes partially reconstitutes fat absorption in chronically bile-diverted rats.
Biochimica et biophysica acta 2004;1636(2-3):90-8.
2004: Bandsma Robert H J; Van Dijk Theo H; Harmsel At Anke ter; Kok Tineke; Reijngoud Dirk-Jan; Staels Bart; Kuipers Folkert
Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short term fast.
The Journal of biological chemistry 2004;279(10):8930-7.
2004: Plösch Torsten; Bloks Vincent W; Terasawa Yuko; Berdy Sara; Siegler Karen; Van Der Sluijs Fjodor; Kema Ido P; Groen Albert K; Shan Bei; Kuipers Folkert; Schwarz Margrit;
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
Gastroenterology 2004;126(1):290-300.
2004: Bloks V W; Bakker-Van Waarde W M; Verkade H J; Kema I P; Wolters H; Vink E; Groen A K; Kuipers F
Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes.
Diabetologia 2004;47(1):104-12.
2004: Groen Albert K; Oude Elferink Ronald P J; Verkade Henkian J; Kuipers Folkert
The ins and outs of reverse cholesterol transport.
Annals of medicine 2004;36(2):135-45.
2003: Elzinga Baukje M; Baller Julius F W; Mensenkamp Arjen R; Yao Zemin; Agellon Luis B; Kuipers Folkert; Verkade Henkjan J
Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.
Biochimica et biophysica acta 2003;1635(2-3):93-103.
2003: van Dijk Theo H; Boer Theo S; Havinga Rick; Stellaard Frans; Kuipers Folkert; Reijngoud Dirk-Jan
Quantification of hepatic carbohydrate metabolism in conscious mice using serial blood and urine spots.
Analytical biochemistry 2003;322(1):1-13.
2003: Kok Tineke; Hulzebos Christian V; Wolters Henk; Havinga Rick; Agellon Luis B; Stellaard Frans; Shan Bei; Schwarz Margrit; Kuipers Folkert
Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein.
The Journal of biological chemistry 2003;278(43):41930-7.
2003: Bisschop P H; De Sain-Van Der Velden M G M; Stellaard F; Kuipers F; Meijer A J; Sauerwein H P; Romijn J A
Dietary carbohydrate deprivation increases 24-hour nitrogen excretion without affecting postabsorptive hepatic or whole body protein metabolism in healthy men.
The Journal of clinical endocrinology and metabolism 2003;88(8):3801-5.
2003: Ros J E; Roskams T A D; Geuken M; Havinga R; Splinter P L; Petersen B E; LaRusso N F; van der Kolk D M; Kuipers F; Faber K N; Müller M; Jansen P L M
ATP binding cassette transporter gene expression in rat liver progenitor cells.
Gut 2003;52(7):1060-7.
2003: Barbier Olivier; Torra Ines Pineda; Sirvent Audrey; Claudel Thierry; Blanquart Christophe; Duran-Sandoval Daniel; Kuipers Folkert; Kosykh Vladimir; Fruchart Jean-Charles; Staels Bart
FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.
Gastroenterology 2003;124(7):1926-40.
2003: Kosters Astrid; Frijters Raoul J J M; Schaap Frank G; Vink Edwin; Plösch Torsten; Ottenhoff Roelof; Jirsa Milan; De Cuyper Iris M; Kuipers Folkert; Groen Albert K
Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice.
Journal of hepatology 2003;38(6):710-6.
2003: Van Eck Miranda; Twisk Jaap; Hoekstra Menno; Van Rij Brechje T; Van der Lans Christian A C; Bos I Sophie T; Kruijt J Kar; Kuipers Folkert; Van Berkel Theo J C
Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver.
The Journal of biological chemistry 2003;278(26):23699-705.
2003: Wiegman Coen H; Bandsma Robert H J; Ouwens Margriet; van der Sluijs Fjodor H; Havinga Rick; Boer Theo; Reijngoud Dirk-Jan; Romijn Johannes A; Kuipers Folkert
Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin.
Diabetes 2003;52(5):1081-9.
2003: Libbrecht Louis; Meerman Leo; Kuipers Folkert; Roskams Tania; Desmet Valeer; Jansen Peter
Liver pathology and hepatocarcinogenesis in a long-term mouse model of erythropoietic protoporphyria.
The Journal of pathology 2003;199(2):191-200.
2003: Kok Tineke; Bloks Vincent W; Wolters Henk; Havinga Rick; Jansen Peter L M; Staels Bart; Kuipers Folkert
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
The Biochemical journal 2003;369(Pt 3):539-47.
2003: Kok Tineke; Wolters Henk; Bloks Vincent W; Havinga Rick; Jansen Peter L M; Staels Bart; Kuipers Folkert
Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse.
Gastroenterology 2003;124(1):160-71.
2003: Hulzebos Christian V; Wolters Henk; Plösch Torsten; Kramer Werner; Stengelin Siegfried; Stellaard Frans; Sauer Pieter J J; Verkade Henkjan J; Kuipers Folkert
Cyclosporin a and enterohepatic circulation of bile salts in rats: decreased cholate synthesis but increased intestinal reabsorption.
The Journal of pharmacology and experimental therapeutics 2003;304(1):356-63.
2003: Jonkers I J A M; Smelt A H M; Ledeboer M; Hollum M E; Biemond I; Kuipers F; Stellaard F; Boverhof R; Meinders A E; Lamers C H B W; Masclee A A M
Gall bladder dysmotility: a risk factor for gall stone formation in hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and fish oil.
Gut 2003;52(1):109-15.
2002: Jonker Johan W; Buitelaar Marije; Wagenaar Els; Van Der Valk Martin A; Scheffer George L; Scheper Rik J; Plosch Torsten; Kuipers Folkert; Elferink Ronald P J Oude; Rosing Hilde; Beijnen Jos H; Schinkel Alfred H
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15649-54.
2002: Wolters Henk; Elzinga Baukje M; Baller Julius F W; Boverhof Renze; Schwarz Margrit; Stieger Bruno; Verkade Henkjan J; Kuipers Folkert
Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice.
Journal of hepatology 2002;37(5):556-63.
2002: Elzinga Baukje M; Havinga Rick; Baller Julius F W; Wolters Henk; Bloks Vincent; Mensenkamp Arjen R; Kuipers Folkert; Verkade Henkjan J
The role of transhepatic bile salt flux in the control of hepatic secretion of triacylglycerol-rich lipoproteins in vivo in rodents.
Biochimica et biophysica acta 2002;1573(1):9-20.
2002: Bandsma Robert H J; Smit G Peter A; Kuipers Folkert
Disturbed lipid metabolism in glycogen storage disease type 1.
European journal of pediatrics 2002;161 Suppl 1():S65-9.
2002: Werner Anniek; Minich Deanna M; Havinga Rick; Bloks Vincent; Van Goor Harry; Kuipers Folkert; Verkade Henkjan J
Fat malabsorption in essential fatty acid-deficient mice is not due to impaired bile formation.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G900-8.
2002: Gustafson Lori A; Kuipers Folkert; Wiegman Coen; Sauerwein Hans P; Romijn Johannes A; Meijer Alfred J
Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity.
Journal of hepatology 2002;37(4):425-31.
2002: Plosch Torsten; Kok Tineke; Bloks Vincent W; Smit Martin J; Havinga Rick; Chimini Giovanna; Groen Albert K; Kuipers Folkert
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.
The Journal of biological chemistry 2002;277(37):33870-7.
2002: Grefhorst Aldo; Elzinga Baukje M; Voshol Peter J; Plösch Torsten; Kok Tineke; Bloks Vincent W; van der Sluijs Fjodor H; Havekes Louis M; Romijn Johannes A; Verkade Henkjan J; Kuipers Folkert
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
The Journal of biological chemistry 2002;277(37):34182-90.
2002: Bisschop Peter H; Ackermans Mariëtte T; Endert Erik; Ruiter An F C; Meijer Alfred J; Kuipers Folkert; Sauerwein Hans P; Romijn Johannes A
The effect of carbohydrate and fat variation in euenergetic diets on postabsorptive free fatty acid release.
The British journal of nutrition 2002;87(6):555-9.
2002: van Waarde Willie M; Verkade Henkjan J; Wolters Henk; Havinga Rick; Baller Juul; Bloks Vincent; Müller Michael; Sauer Pieter J J; Kuipers Folkert
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats.
Gastroenterology 2002;122(7):1842-52.
2002: Claudel Thierry; Sturm Ekkehard; Duez Hélène; Torra Inés Pineda; Sirvent Audrey; Kosykh Vladimir; Fruchart Jean-Charles; Dallongeville Jean; Hum Dean W; Kuipers Folkert; Staels Bart
Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.
The Journal of clinical investigation 2002;109(7):961-71.
2002: Bandsma Robert H J; Rake Jan-Peter; Visser Gepke; Neese Richard A; Hellerstein Marc K; van Duyvenvoorde Wim; Princen Hans M G; Stellaard Frans; Smit G Peter A; Kuipers Folkert
Increased lipogenesis and resistance of lipoproteins to oxidative modification in two patients with glycogen storage disease type 1a.
The Journal of pediatrics 2002;140(2):256-60.
2002: Plösch Torsten; Bloks Vincent W; Baller Juul F W; Havinga Rick; Verkade Henkjan J; Jansen Peter L M; Kuipers Folkert
Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.
Hepatology (Baltimore, Md.) 2002;35(2):299-306.
2002: Sturm E; Franssen C F M; Gouw A; Staels B; Boverhof R; De Knegt R J; Stellaard F; Bijleveld C M A; Kuipers F
Extracorporal albumin dialysis (MARS) improves cholestasis and normalizes low apo A-I levels in a patient with benign recurrent intrahepatic cholestasis (BRIC).
Liver 2002;22 Suppl 2():72-5.
2001: Mensenkamp A R; Havekes L M; Romijn J A; Kuipers F
Hepatic steatosis and very low density lipoprotein secretion: the involvement of apolipoprotein E.
Journal of hepatology 2001;35(6):816-22.
2001: Hulzebos C V; Renfurm L; Bandsma R H; Verkade H J; Boer T; Boverhof R; Tanaka H; Mierau I; Sauer P J; Kuipers F; Stellaard F
Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans.
Journal of lipid research 2001;42(11):1923-9.
2001: Post S M; Duez H; Gervois P P; Staels B; Kuipers F; Princen H M
Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1840-5.
2001: Bandsma R H; Wiegman C H; Herling A W; Burger H J; ter Harmsel A; Meijer A J; Romijn J A; Reijngoud D J; Kuipers F
Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats.
Diabetes 2001;50(11):2591-7.
2001: Teusink B; Mensenkamp A R; van der Boom H; Kuipers F; van Dijk K W; Havekes L M
Stimulation of the in vivo production of very low density lipoproteins by apolipoprotein E is independent of the presence of the low density lipoprotein receptor.
The Journal of biological chemistry 2001;276(44):40693-7.
2001: Groen A K; Bloks V W; Bandsma R H; Ottenhoff R; Chimini G; Kuipers F
Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL.
The Journal of clinical investigation 2001;108(6):843-50.
2001: Gustafson L A; Neeft M; Reijngoud D J; Kuipers F; Sauerwein H P; Romijn J A; Herling A W; Burger H J; Meijer A J
Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.
The Biochemical journal 2001;358(Pt 3):665-71.
2001: Mensenkamp A R; Teusink B; Baller J F; Wolters H; Havinga R; van Dijk K W; Havekes L M; Kuipers F
Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(8):1366-72.
2001: van Dijk T H; van der Sluijs F H; Wiegman C H; Baller J F; Gustafson L A; Burger H J; Herling A W; Kuipers F; Meijer A J; Reijngoud D J
Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.
The Journal of biological chemistry 2001;276(28):25727-35.
2001: Ros J E; Schuetz J D; Geuken M; Streetz K; Moshage H; Kuipers F; Manns M P; Jansen P L; Trautwein C; Müller M
Induction of Mdr1b expression by tumor necrosis factor-alpha in rat liver cells is independent of p53 but requires NF-kappaB signaling.
Hepatology (Baltimore, Md.) 2001;33(6):1425-31.
2001: Voshol P J; Schwarz M; Rigotti A; Krieger M; Groen A K; Kuipers F
Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine.
The Biochemical journal 2001;356(Pt 2):317-25.
2001: Adage T; Scheurink A J; de Boer S F; de Vries K; Konsman J P; Kuipers F; Adan R A; Baskin D G; Schwartz M W; van Dijk G
Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):3639-45.
2001: Smit-van Oosten A; Navis G; Stegeman C A; Joles J A; Klok P A; Kuipers F; Tiebosch A T; van Goor H
Chronic blockade of angiotensin II action prevents glomerulosclerosis, but induces graft vasculopathy in experimental kidney transplantation.
The Journal of pathology 2001;194(1):122-9.
2001: Bisschop P H; de Metz J; Ackermans M T; Endert E; Pijl H; Kuipers F; Meijer A J; Sauerwein H P; Romijn J A
Dietary fat content alters insulin-mediated glucose metabolism in healthy men.
The American journal of clinical nutrition 2001;73(3):554-9.
2001: Voshol P J; Koopen N R; de Vree J M; Havinga R; Princen H M; Elferink R P; Groen A K; Kuipers F
Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice.
Journal of hepatology 2001;34(2):202-9.
2001: Bloks V W; Plösch T; van Goor H; Roelofsen H; Baller J; Havinga R; Verkade H J; van Tol A; Jansen P L; Kuipers F
Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice.
Journal of lipid research 2001;42(1):41-50.
2000: Minich D M; Havinga R; Stellaard F; Vonk R J; Kuipers F; Verkade H J
Intestinal absorption and postabsorptive metabolism of linoleic acid in rats with short-term bile duct ligation.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1242-8.
2000: Benthem L; Keizer K; Wiegman C H; de Boer SF; Strubbe J H; Steffens A B; Kuipers F; Scheurink A J
Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation.
American journal of physiology. Endocrinology and metabolism 2000;279(6):E1286-93.
2000: Roelofsen H; Wolters H; Van Luyn M J; Miura N; Kuipers F; Vonk R J
Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion.
Gastroenterology 2000;119(3):782-93.
2000: Mensenkamp A R; van Luyn M J; van Goor H; Bloks V; Apostel F; Greeve J; Hofker M H; Jong M C; van Vlijmen B J; Havekes L M; Kuipers F
Hepatic lipid accumulation, altered very low density lipoprotein formation and apolipoprotein E deposition in apolipoprotein E3-Leiden transgenic mice.
Journal of hepatology 2000;33(2):189-98.
2000: Kalivianakis M; Minich D M; Havinga R; Kuipers F; Stellaard F; Vonk R J; Verkade H J
Detection of impaired intestinal absorption of long-chain fatty acids: validation studies of a novel test in a rat model of fat malabsorption.
The American journal of clinical nutrition 2000;72(1):174-80.
2000: Bisschop P H; Pereira Arias A M; Ackermans M T; Endert E; Pijl H; Kuipers F; Meijer A J; Sauerwein H P; Romijn J A
The effects of carbohydrate variation in isocaloric diets on glycogenolysis and gluconeogenesis in healthy men.
The Journal of clinical endocrinology and metabolism 2000;85(5):1963-7.
2000: Bandsma R H; Kuipers F; Vonk R J; Boverhof R; Sauer P J; Nagel G T; Elzinga H; Neese R A; Hellerstein M K; Stellaard F
The contribution of newly synthesized cholesterol to bile salt synthesis in rats quantified by mass isotopomer distribution analysis.
Biochimica et biophysica acta 2000;1483(3):343-51.
2000: Voshol P J; Minich D M; Havinga R; Elferink R P; Verkade H J; Groen A K; Kuipers F
Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Gastroenterology 2000;118(1):173-82.
1999: Mensenkamp A R; Jong M C; van Goor H; van Luyn M J; Bloks V; Havinga R; Voshol P J; Hofker M H; van Dijk K W; Havekes L M; Kuipers F
Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver.
The Journal of biological chemistry 1999;274(50):35711-8.
1999: Schaefer M; Roelofsen H; Wolters H; Hofmann W J; Müller M; Kuipers F; Stremmel W; Vonk R J
Localization of the Wilson's disease protein in human liver.
Gastroenterology 1999;117(6):1380-5.
1999: Jansen P L; Strautnieks S S; Jacquemin E; Hadchouel M; Sokal E M; Hooiveld G J; Koning J H; De Jager-Krikken A; Kuipers F; Stellaard F; Bijleveld C M; Gouw A; Van Goor H; Thompson R J; Müller M
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.
Gastroenterology 1999;117(6):1370-9.
1999: Benthem L; Kuipers F; Steffens A B; Scheurink A J
Excessive portal venous supply of long-chain free fatty acids to the liver, leading to hypothalamus-pituitary-adrenal-axis and sympathetic activation as a key to the development of syndrome X. A proposed concept for the induction of syndrome X.
Annals of the New York Academy of Sciences 1999;892():308-11.
1999: Minich D M; Voshol P J; Havinga R; Stellaard F; Kuipers F; Vonk R J; Verkade H J
Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice.
Biochimica et biophysica acta 1999;1441(1):14-22.
1999: Kalivianakis M; Elstrodt J; Havinga R; Kuipers F; Stellaard F; Sauer P J; Vonk R J; Verkade H J
Validation in an animal model of the carbon 13-labeled mixed triglyceride breath test for the detection of intestinal fat malabsorption.
The Journal of pediatrics 1999;135(4):444-50.
1999: Meerman L; Koopen N R; Bloks V; Van Goor H; Havinga R; Wolthers B G; Kramer W; Stengelin S; Müller M; Kuipers F; Jansen P L
Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria.
Gastroenterology 1999;117(3):696-705.
1999: Hooiveld G J; Vos T A; Scheffer G L; Van Goor H; Koning H; Bloks V; Loot A E; Meijer D K; Jansen P L; Kuipers F; Müller M
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats.
Gastroenterology 1999;117(3):678-87.
1999: Post S M; Zoeteweij J P; Bos M H; de Wit E C; Havinga R; Kuipers F; Princen H M
Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
Hepatology (Baltimore, Md.) 1999;30(2):491-500.
1999: Vos T A; Ros J E; Havinga R; Moshage H; Kuipers F; Jansen P L; Müller M
Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats.
Hepatology (Baltimore, Md.) 1999;29(6):1833-9.
1999: Minich D M; Kalivianakis M; Havinga R; van Goor H; Stellaard F; Vonk R J; Kuipers F; Verkade H J
Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid.
Biochimica et biophysica acta 1999;1438(1):111-9.
1999: Vos T A; Van Goor H; Tuyt L; De Jager-Krikken A; Leuvenink R; Kuipers F; Jansen P L; Moshage H
Expression of inducible nitric oxide synthase in endotoxemic rat hepatocytes is dependent on the cellular glutathione status.
Hepatology (Baltimore, Md.) 1999;29(2):421-6.
1999: Koopen N R; Wolters H; Voshol P; Stieger B; Vonk R J; Meier P J; Kuipers F; Hagenbuch B
Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice.
Journal of hepatology 1999;30(1):14-21.
1999: Koopen N R; Post S M; Wolters H; Havinga R; Stellaard F; Boverhof R; Kuipers F; Princen H M
Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat.
Journal of lipid research 1999;40(1):100-8.
1998: de Sain-van der Velden M G; Rabelink T J; Gadellaa M M; Elzinga H; Reijngoud D J; Kuipers F; Stellaard F
In vivo determination of very-low-density lipoprotein-apolipoprotein B100 secretion rates in humans with a low dose of l-[1-13C]valine and isotope ratio mass spectrometry.
Analytical biochemistry 1998;265(2):308-12.
1998: Koopen N R; Müller M; Vonk R J; Zimniak P; Kuipers F
Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation.
Biochimica et biophysica acta 1998;1408(1):1-17.
1998: Voshol P J; Havinga R; Wolters H; Ottenhoff R; Princen H M; Oude Elferink R P; Groen A K; Kuipers F
Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Gastroenterology 1998;114(5):1024-34.
1998: Koopen N R; Wolters H; Havinga R; Vonk R J; Jansen P L; Müller M; Kuipers F
Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.
Hepatology (Baltimore, Md.) 1998;27(2):537-45.
1998: Bandsma R H; Stellaard F; Vonk R J; Nagel G T; Neese R A; Hellerstein M K; Kuipers F
Contribution of newly synthesized cholesterol to rat plasma and bile determined by mass isotopomer distribution analysis: bile-salt flux promotes secretion of newly synthesized cholesterol into bile.
The Biochemical journal 1998;329 ( Pt 3)():699-703.
1997: Kuipers F; Jong M C; Lin Y; Eck M; Havinga R; Bloks V; Verkade H J; Hofker M H; Moshage H; Berkel T J; Vonk R J; Havekes L M
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes.
The Journal of clinical investigation 1997;100(11):2915-22.
1997: Koopen N R; Wolters H; Müller M; Schippers I J; Havinga R; Roelofsen H; Vonk R J; Stieger B; Meier P J; Kuipers F
Hepatic bile salt flux does not modulate level and activity of the sinusoidal Na+-taurocholate cotransporter (ntcp) in rats.
Journal of hepatology 1997;27(4):699-706.
1997: Dijkstra M; Kuipers F; van den Berg G J; Havinga R; Vonk R J
Differences in hepatic processing of dietary and intravenously administered copper in rats.
Hepatology (Baltimore, Md.) 1997;26(4):962-6.
1997: Vos T A; Gouw A S; Klok P A; Havinga R; van Goor H; Huitema S; Roelofsen H; Kuipers F; Jansen P L; Moshage H
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.
Gastroenterology 1997;113(4):1323-33.
1997: Schippers I J; Moshage H; Roelofsen H; Müller M; Heymans H S; Ruiters M; Kuipers F
Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation.
Cell biology and toxicology 1997;13(4-5):375-86.
1997: Roelofsen H; Vos T A; Schippers I J; Kuipers F; Koning H; Moshage H; Jansen P L; Müller M
Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells.
Gastroenterology 1997;112(2):511-21.
1997: Verkade H J; Kuipers F; Domingo N; Havinga R; Léonardi J; Vonk R J; Lafont H
Biliary secretion of anionic polypeptide fraction is not coupled to that of phospholipids and cholesterol in rats.
Hepatology (Baltimore, Md.) 1997;25(1):38-47.
1997: Kuipers F; Oude Elferink R P; Verkade H J; Groen A K
Mechanisms and (patho)physiological significance of biliary cholesterol secretion.
Sub-cellular biochemistry 1997;28():295-318.
1996: Verkade H J; de Bruijn M A; Brink M A; Talsma H; Vonk R J; Kuipers F; Groen A K
Interactions between organic anions, micelles and vesicles in model bile systems.
The Biochemical journal 1996;320 ( Pt 3)():917-23.
1996: Dijkstra M; van den Berg G J; Wolters H; In't Veld G; Slooff M J; Heymans H S; Kuipers F; Vonk R J
Adenosine triphosphate-dependent copper transport in human liver.
Journal of hepatology 1996;25(1):37-42.
1996: Kuipers F; van Ree J M; Hofker M H; Wolters H; In't Veld G; Havinga R; Vonk R J; Princen H M; Havekes L M
Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver.
Hepatology (Baltimore, Md.) 1996;24(1):241-7.
1996: Lin Y; Havinga R; Schippers I J; Verkade H J; Vonk R J; Kuipers F
Characterization of the inhibitory effects of bile acids on very-low-density lipoprotein secretion by rat hepatocytes in primary culture.
The Biochemical journal 1996;316 ( Pt 2)():531-8.
1996: Beukeveld G J; In 't Veld G; Havinga R; Groen A K; Wolthers B G; Kuipers F
Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport.
Journal of hepatology 1996;24(3):343-52.
1996: Lin Y; Havinga R; Verkade H J; Moshage H; Slooff M J; Vonk R J; Kuipers F
Bile acids suppress the secretion of very-low-density lipoprotein by human hepatocytes in primary culture.
Hepatology (Baltimore, Md.) 1996;23(2):218-28.
1996: Dijkstra M; Vonk R J; Kuipers F
How does copper get into bile? New insights into the mechanism(s) of hepatobiliary copper transport.
Journal of hepatology 1996;24 Suppl 1():109-20.
1996: Dijkstra M; Havinga R; Vonk R J; Kuipers F
Bile secretion of cadmium, silver, zinc and copper in the rat. Involvement of various transport systems.
Life sciences 1996;59(15):1237-46.
1995: Beukeveld G J; Bijleveld C M; Kuipers F; Kreeftenberg H G; Huizenga J R; te Velde K; Wolthers B G
Evaluation and clinical application of the Enterotest for the determination of human biliary porphyrin composition.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1995;33(7):453-62.
1995: Lin Y; Smit M J; Havinga R; Verkade H J; Vonk R J; Kuipers F
Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat hepatocytes.
Biochimica et biophysica acta 1995;1256(1):88-96.
1995: Verkade H J; Vonk R J; Kuipers F
New insights into the mechanism of bile acid-induced biliary lipid secretion.
Hepatology (Baltimore, Md.) 1995;21(4):1174-89.
1995: Dijkstra M; In 't Veld G; van den Berg G J; Müller M; Kuipers F; Vonk R J
Adenosine triphosphate-dependent copper transport in isolated rat liver plasma membranes.
The Journal of clinical investigation 1995;95(1):412-6.
1994: Smit M J; Verkade H J; Havinga R; Vonk R J; Scherphof G L; In 't Veld G; Kuipers F
Dietary fish oil potentiates bile acid-induced cholesterol secretion into bile in rats.
Journal of lipid research 1994;35(2):301-10.
1994: Smit M J; Wolters H; Temmerman A M; Kuipers F; Beynen A C; Vonk R J
Effects of dietary corn and olive oil versus coconut fat on biliary cholesterol secretion in rats.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1994;64(1):75-80.
1993: Verkade H J; Wolters H; Gerding A; Havinga R; Fidler V; Vonk R J; Kuipers F
Mechanism of biliary lipid secretion in the rat: a role for bile acid-independent bile flow?
Hepatology (Baltimore, Md.) 1993;17(6):1074-80.
1993: Dijkstra M; Kuipers F; Smit E P; Havinga R; Vonk R J
The role of glutathione in bile secretion of endogenous trace elements in rats.
The Journal of laboratory and clinical medicine 1993;121(6):751-8.
1993: Verkade H J; Havinga R; Gerding A; Vonk R J; Kuipers F
Mechanism of bile acid-induced biliary lipid secretion in the rat: effect of conjugated bilirubin.
The American journal of physiology 1993;264(3 Pt 1):G462-9.
1993: Smit M J; Kuipers F; Vonk R J; Temmerman A M; Jäckle S; Windler E E
Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat.
Hepatology (Baltimore, Md.) 1993;17(3):445-54.
1992: Wolters H; Kuipers F; Slooff M J; Vonk R J
Adenosine triphosphate-dependent taurocholate transport in human liver plasma membranes.
The Journal of clinical investigation 1992;90(6):2321-6.
1992: Verkade H J; Zaal K J; Derksen J T; Vonk R J; Hoekstra D; Kuipers F; Scherphof G L
Processing of the phospholipid analogue phosphatidyl(N-sulphorhodamine B sulphonyl)ethanolamine by rat hepatocytes in vitro and in vivo.
The Biochemical journal 1992;284 ( Pt 1)():259-65.
1992: Kuipers F; Hardonk M J; Vonk R J; van der Meer R
Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats.
The American journal of physiology 1992;262(2 Pt 1):G267-73.
1991: Wolters H; Spiering M; Gerding A; Slooff M J; Kuipers F; Hardonk M J; Vonk R J
Isolation and characterization of canalicular and basolateral plasma membrane fractions from human liver.
Biochimica et biophysica acta 1991;1069(1):61-9.
1991: Smit M J; Temmerman A M; Wolters H; Kuipers F; Beynen A C; Vonk R J
Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats.
The Journal of clinical investigation 1991;88(3):943-51.
1991: Dijkstra M; Kuipers F; Smit E P; de Vries J J; Havinga R; Vonk R J
Biliary secretion of trace elements and minerals in the rat. Effects of bile flow variation and diurnal rhythms.
Journal of hepatology 1991;13(1):112-9.
1991: Verkade H J; Derksen J T; Gerding A; Scherphof G L; Vonk R J; Kuipers F
Differential hepatic processing and biliary secretion of head-group and acyl chains of liposomal phosphatidylcholines.
The Biochemical journal 1991;275 ( Pt 1)():139-44.
1991: Oude Elferink R P; Ottenhoff R; Radominska A; Hofmann A F; Kuipers F; Jansen P L
Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions.
The Biochemical journal 1991;274 ( Pt 1)():281-6.
1990: Verkade H J; Wolbers M J; Havinga R; Uges D R; Vonk R J; Kuipers F
The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat.
Gastroenterology 1990;99(5):1485-92.
1990: Dijkstra M; Kuipers F; Havinga R; Smit E P; Vonk R J
Bile secretion of trace elements in rats with a congenital defect in hepatobiliary transport of glutathione.
Pediatric research 1990;28(4):339-43.
1990: Smit M J; Temmerman A M; Havinga R; Kuipers F; Vonk R J
Short- and long-term effects of biliary drainage on hepatic cholesterol metabolism in the rat.
The Biochemical journal 1990;269(3):781-8.
1990: Bakkeren H F; Kuipers F; Vonk R J; Van Berkel T J
Evidence for reverse cholesterol transport in vivo from liver endothelial cells to parenchymal cells and bile by high-density lipoprotein.
The Biochemical journal 1990;268(3):685-91.
1990: Houwen R; Dijkstra M; Kuipers F; Smit E P; Havinga R; Vonk R J
Two pathways for biliary copper excretion in the rat. The role of glutathione.
Biochemical pharmacology 1990;39(6):1039-44.
1989: Kuipers F; Radominska A; Zimniak P; Little J M; Havinga R; Vonk R J; Lester R
Defective biliary secretion of bile acid 3-O-glucuronides in rats with hereditary conjugated hyperbilirubinemia.
Journal of lipid research 1989;30(12):1835-45.
1989: Kuipers F; Havinga R; Huijsmans C M; Vonk R J; Princen H M
Inhibition and induction of bile acid synthesis by ketoconazole. Effects on bile formation in the rat.
Lipids 1989;24(9):759-64.
1989: Bijleveld C M; Vonk R J; Kuipers F; Havinga R; Boverhof R; Koopman B J; Wolthers B G; Fernandes J
Benign recurrent intrahepatic cholestasis: altered bile acid metabolism.
Gastroenterology 1989;97(2):427-32.
1989: Polhuijs M; Kuipers F; Vonk R J; Mulder G J
Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
The Journal of pharmacology and experimental therapeutics 1989;249(3):874-8.
1989: Kuipers F; Nagelkerke J F; Bakkeren H; Havinga R; Van Berkel T J; Vonk R J
Processing of cholesteryl ester from low-density lipoproteins in the rat. Hepatic metabolism and biliary secretion after uptake by different hepatic cell types.
The Biochemical journal 1989;257(3):699-704.
1988: Koopman B J; Kuipers F; Bijleveld C M; van der Molen J C; Nagel G T; Vonk R J; Wolthers B G
Determination of cholic acid and chenodeoxycholic acid pool sizes and fractional turnover rates by means of stable isotope dilution technique, making use of deuterated cholic acid and chenodeoxycholic acid.
Clinica chimica acta; international journal of clinical chemistry 1988;175(2):143-55.
1988: Kuipers F; Enserink M; Havinga R; van der Steen A B; Hardonk M J; Fevery J; Vonk R J
Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat.
The Journal of clinical investigation 1988;81(5):1593-9.
1988: van Berkel T J; Kuipers F; Nagelkerke J F; Bakkeren H F; Havinga R; Vonk R J
Processing of cholesteryl ester from low density lipoproteins in the rat: hepatic metabolism and biliary excretion after uptake by different hepatic cells.
Agents and actions. Supplements 1988;26():99-107.
1987: Scherphof G L; Kuipers F; Derksen J T; Spanjer H H; Vonk R J
Liposomes in vivo; conversion of liposomal cholesterol to bile salts.
Biochemical Society transactions 1987;15 Suppl():62S-68S.
1987: Kuipers F; Derksen J P; Gerding A; Scherphof G L; Vonk R J
Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid.
Biochimica et biophysica acta 1987;922(2):136-44.
1987: Scherphof G L; Spanjer H H; Derksen J T; Kuipers F; Vonk R J; Daemen T; Roerdink F H
Delivery of liposome-associated drugs to liver cells.
Biochemical Society transactions 1987;15(3):345-8.
1986: Nagelkerke J F; Bakkeren H F; Kuipers F; Vonk R J; van Berkel T J
Hepatic processing of the cholesteryl ester from low density lipoprotein in the rat.
The Journal of biological chemistry 1986;261(19):8908-13.
1986: Kuipers F; Spanjer H H; Havinga R; Scherphof G L; Vonk R J
Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids.
Biochimica et biophysica acta 1986;876(3):559-66.

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