FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

jeffrey smith

Research Profile

Chemicals & Drugs

Phenomena

Phosphorylation

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Living Beings

Co-author Network

Publications

TOP 3
jeffrey smith; David J Maloney; Sidney Hecht; Deborah A Lannigan
Structural basis for the activity of the RSK-specific inhibitor, SL0101.
Tam L Nguyen; Rick Gussio; jeffrey smith; Deborah A Lannigan; Sidney Hecht; Dominic A Scudiero; Robert H Shoemaker; Daniel W Zaharevitz
Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore.
jeffrey smith; David J Maloney; David E Clark; Yaming Xu; Sidney Hecht; Deborah A Lannigan
Influence of rhamnose substituents on the potency of SL0101, an inhibitor of the Ser/Thr kinase, RSK.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of jeffrey smith (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2007: jeffrey smith; David J Maloney; Sidney Hecht; Deborah A Lannigan
Structural basis for the activity of the RSK-specific inhibitor, SL0101.
Bioorganic & medicinal chemistry 2007;15(14):5018-34.
2006: Tam L Nguyen; Rick Gussio; jeffrey smith; Deborah A Lannigan; Sidney Hecht; Dominic A Scudiero; Robert H Shoemaker; Daniel W Zaharevitz
Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore.
Bioorganic & medicinal chemistry 2006;14(17):6097-105.
2006: jeffrey smith; David J Maloney; David E Clark; Yaming Xu; Sidney Hecht; Deborah A Lannigan
Influence of rhamnose substituents on the potency of SL0101, an inhibitor of the Ser/Thr kinase, RSK.
Bioorganic & medicinal chemistry 2006;14(17):6034-42.
2006: Ya-ming Xu; jeffrey smith; Deborah A Lannigan; Sidney Hecht
Three acetylated flavonol glycosides from Forsteronia refracta that specifically inhibit p90 RSK.
Bioorganic & medicinal chemistry 2006;14(11):3974-7.
2005: David E Clark; Timothy M Errington; jeffrey smith; Henry F Frierson; Michael J Weber; Deborah A Lannigan
The serine/threonine protein kinase, p90 ribosomal S6 kinase, is an important regulator of prostate cancer cell proliferation.
Cancer research 2005;65(8):3108-16.
2005: jeffrey smith; Celeste E Poteet-Smith; Yaming Xu; Timothy M Errington; Sidney Hecht; Deborah A Lannigan
Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation.
Cancer research 2005;65(3):1027-34.
2003: Lorin M Henrich; jeffrey smith; Danielle Kitt; Timothy M Errington; Binh Nguyen; Abdulmaged M Traish; Deborah A Lannigan
Extracellular signal-regulated kinase 7, a regulator of hormone-dependent estrogen receptor destruction.
Molecular and cellular biology 2003;23(17):5979-88.
2001: David E Clark; Celeste E Poteet-Smith; jeffrey smith; Deborah A Lannigan
Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.
The EMBO journal 2001;20(13):3484-94.
2000: jeffrey smith; Celeste E Poteet-Smith; Deborah A Lannigan; T A Freed; A J Zoltoski; Thomas W Sturgill
Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function.
The Journal of biological chemistry 2000;275(41):31588-93.
2000: Theodore S Steiner; James P Nataro; Celeste E Poteet-Smith; jeffrey smith; Richard L Guerrant
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.
The Journal of clinical investigation 2000;105(12):1769-77.
2000: jeffrey smith; R B Reed; Sharron H Francis; Kennard A Grimes; Jackie D Corbin
Distinguishing the roles of the two different cGMP-binding sites for modulating phosphorylation of exogenous substrate (heterophosphorylation) and autophosphorylation of cGMP-dependent protein kinase.
The Journal of biological chemistry 2000;275(1):154-8.
1999: Celeste E Poteet-Smith; jeffrey smith; Deborah A Lannigan; T A Freed; Thomas W Sturgill
Generation of constitutively active p90 ribosomal S6 kinase in vivo. Implications for the mitogen-activated protein kinase-activated protein kinase family.
The Journal of biological chemistry 1999;274(32):22135-8.
1999: jeffrey smith; Celeste E Poteet-Smith; K Malarkey; Thomas W Sturgill
Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo.
The Journal of biological chemistry 1999;274(5):2893-8.
1998: P B Joel; jeffrey smith; Thomas W Sturgill; T L Fisher; John Blenis; Deborah A Lannigan
pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167.
Molecular and cellular biology 1998;18(4):1978-84.
1996: jeffrey smith; Sharron H Francis; KA Walsh; S Kumar; Jackie D Corbin
Autophosphorylation of type Ibeta cGMP-dependent protein kinase increases basal catalytic activity and enhances allosteric activation by cGMP or cAMP.
The Journal of biological chemistry 1996;271(34):20756-62.
1996: Sharron H Francis; jeffrey smith; J L Colbran; Kennard A Grimes; KA Walsh; S Kumar; Jackie D Corbin
Arginine 75 in the pseudosubstrate sequence of type Ibeta cGMP-dependent protein kinase is critical for autoinhibition, although autophosphorylated serine 63 is outside this sequence.
The Journal of biological chemistry 1996;271(34):20748-55.
1993: jeffrey smith; S H Francis; J D Corbin
Autophosphorylation: a salient feature of protein kinases.
Molecular and cellular biochemistry 1993;127-128():51-70.
1990: S J Taylor; jeffrey smith; John H Exton
Purification from bovine liver membranes of a guanine nucleotide-dependent activator of phosphoinositide-specific phospholipase C. Immunologic identification as a novel G-protein alpha subunit.
The Journal of biological chemistry 1990;265(28):17150-6.
1988: C J Lynch; S J Taylor; jeffrey smith; John H Exton
Formation of the high-affinity agonist state of the alpha 1-adrenergic receptor at cold temperatures does not require a G-protein.
FEBS letters 1988;229(1):54-8.