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Robbert van der Most

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Philippe Moris; Robbert van der Most; Frédéric Clement; Mamadou Dramé; Emmanuel Hanon; Geert G Leroux-Roels; Isabel Leroux-Roels; Marcelle Van Mechelen
H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses.
Adriaan F.G. Antonis; Marina C de Jong; Wim H M van der Poel; Robbert van der Most; Norbert Stockhofe-Zurwieden; Tjeerd G Kimman; remco schrijver
Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence.
Isabel Leroux-Roels; François Roman; Sheron Forgus; Cathy Maes; Fien De Boever; Mamadou Dramé; Paul Gillard; Robbert van der Most; Marcelle Van Mechelen; Emmanuel Hanon; Geert Leroux-Roels
Priming with AS03 A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study.

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All Publications

2011: Philippe Moris; Robbert van der Most; Frédéric Clement; Mamadou Dramé; Emmanuel Hanon; Geert G Leroux-Roels; Isabel Leroux-Roels; Marcelle Van Mechelen
H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses.
Journal of clinical immunology 2011;31(3):443-54.
2010: Adriaan F.G. Antonis; Marina C de Jong; Wim H M van der Poel; Robbert van der Most; Norbert Stockhofe-Zurwieden; Tjeerd G Kimman; remco schrijver
Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence.
The Journal of general virology 2010;91(Pt 10):2497-506.
2010: Isabel Leroux-Roels; François Roman; Sheron Forgus; Cathy Maes; Fien De Boever; Mamadou Dramé; Paul Gillard; Robbert van der Most; Marcelle Van Mechelen; Emmanuel Hanon; Geert Leroux-Roels
Priming with AS03 A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study.
Vaccine 2010;28(3):849-57.
2009: Andrew J Currie; Amy Prosser; Alison McDonnell; Amanda L Cleaver; Bruce W S Robinson; Gordon J Freeman; Robbert van der Most
Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: regulation and counterregulation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(12):7898-908.
2009: Steve A Broomfield; Robbert van der Most; Amy C Prosser; Sathish Mahendran; Michael G Tovey; Mark J Smyth; Bruce W S Robinson; Andrew J Currie
Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5217-24.
2009: Joseph N Blattman; E John Wherry; Sang-Jun Ha; Robbert van der Most; Rafi Ahmed
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection.
Journal of virology 2009;83(9):4386-94.
2008: Joseph D Miller; Robbert van der Most; Rama S Akondy; John T Glidewell; Sophia Albott; David Masopust; Kaja Murali-Krishna; Patryce L Mahar; Srilatha Edupuganti; Susan Lalor; Stephanie Germon; Carlos del Rio; Mark MULLIGAN; Silvija I Staprans; John D Altman; Mark B Feinberg; Rafi Ahmed
Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines.
Immunity 2008;28(5):710-22.
2008: Andrew Currie; Robbert van der Most; Steve A Broomfield; Amy C Prosser; Michael G Tovey; Bruce W S Robinson
Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1535-44.
2008: Robbert van der Most; Andrew Currie; Bruce W S Robinson; Richard A Lake
Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all.
Cell death and differentiation 2008;15(1):13-20.
2007: Erwin A W Claassen; Grada M van Bleek; Zuzana S Rychnavska; Raoul J de Groot; Evert J Hensen; Edwin J Tijhaar; Willem van Eden; Robbert van der Most
Identification of a CD4 T cell epitope in the pneumonia virus of mice glycoprotein and characterization of its role in protective immunity.
Virology 2007;368(1):17-25.
2007: Adriaan F.G. Antonis; Robbert van der Most; Yasemin Suezer; Norbert Stockhofe-Zurwieden; Franz Daus; Gerd Sutter; remco schrijver
Vaccination with recombinant modified vaccinia virus Ankara expressing bovine respiratory syncytial virus (bRSV) proteins protects calves against RSV challenge.
Vaccine 2007;25(25):4818-27.
2006: Robbert van der Most; Bruce W S Robinson; Delia J Nelson
Gene therapy for malignant mesothelioma: beyond the infant years.
Cancer gene therapy 2006;13(10):897-904.
2006: Michaël V Lukens; Erwin A W Claassen; Patricia M A De Graaff; Mariska E A van Dijk; Peter Hoogerhout; Mireille Toebes; Schumacher Ton; Robbert van der Most; Jan L L Kimpen; Grada M van Bleek
Characterization of the CD8+ T cell responses directed against respiratory syncytial virus during primary and secondary infection in C57BL/6 mice.
Virology 2006;352(1):157-68.
2006: Richard A Lake; Robbert van der Most
A better way for a cancer cell to die.
The New England journal of medicine 2006;354(23):2503-4.
2006: Adriaan F.G. Antonis; Erwin A W Claassen; Evert J Hensen; Raoul J de Groot; Jolanda D F de Groot-Mijnes; remco schrijver; Robbert van der Most
Kinetics of antiviral CD8 T cell responses during primary and post-vaccination secondary bovine respiratory syncytial virus infection.
Vaccine 2006;24(10):1551-61.
2006: Robbert van der Most; Robyn Himbeck; Simon Aarons; Stephen J Carter; Irma Larma; Cleo Robinson; Andrew Currie; Richard A Lake
Antitumor efficacy of the novel chemotherapeutic agent coramsine is potentiated by cotreatment with CpG-containing oligodeoxynucleotides.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(2):134-42.
2006: Robbert van der Most; Andrew Currie; Bruce W S Robinson; Richard A Lake
Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity.
Cancer research 2006;66(2):601-4.
2005: Erwin A W Claassen; Patrick A A van der Kant; Zuzana S Rychnavska; Grada M van Bleek; Andrew J Easton; Robbert van der Most
Activation and inactivation of antiviral CD8 T cell responses during murine pneumovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6597-604.
2005: Steve Broomfield; Andrew Currie; Robbert van der Most; Matthew Brown; Ivonne van Bruggen; Bruce W S Robinson; Richard A Lake
Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy.
Cancer research 2005;65(17):7580-4.
2005: Delia J Nelson; Bruce W S Robinson; Jane Allan; Robbert van der Most
Gene therapy of mesothelioma.
Expert opinion on biological therapy 2005;5(8):1039-49.
2005: Antonio Scibelli; Robbert van der Most; Johan A Turkstra; Mark P Ariaans; Ger Arkesteijn; Evert J Hensen; Rob H Meloen
Fast track selection of immunogens for novel vaccines through visualisation of the early onset of the B-cell response.
Vaccine 2005;23(16):1900-9.
2005: Jolanda D F de Groot-Mijnes; Jessica M van Dun; Robbert van der Most; Raoul J de Groot
Natural history of a recurrent feline coronavirus infection and the role of cellular immunity in survival and disease.
Journal of virology 2005;79(2):1036-44.
2004: Ernst C Soethout; Adriaan F.G. Antonis; L H Ulfman; Aad Hoek; Robbert van der Most; Kerstin E Müller; V P M G Rutten
Bovine respiratory syncytial virus infection influences the impact of alpha- and beta-integrin-mediated adhesion of peripheral blood neutrophils.
Clinical and experimental immunology 2004;138(3):388-95.
2004: Patricia M A De Graaff; Jojanneke Heidema; Martien C M Poelen; Mariska E A van Dijk; Michael V Lukens; Sjef P J van Gestel; Judith Reinders; Erik H Rozemuller; Marcel Tilanus; Peter Hoogerhout; Cécile A C M van Els; Robbert van der Most; Jan L L Kimpen; Grada M van Bleek
HLA-DP4 presents an immunodominant peptide from the RSV G protein to CD4 T cells.
Virology 2004;326(2):220-30.
2004: Jolanda D F de Groot-Mijnes; Robbert van der Most; Jessica M van Dun; Eddie G te Lintelo; N M P Schuurman; Herman F Egberink; Raoul J de Groot
Three-color flow cytometry detection of virus-specific CD4+ and CD8+ T cells in the cat.
Journal of immunological methods 2004;285(1):41-54.
2003: Adriaan F.G. Antonis; remco schrijver; Franz Daus; Paul J G M Steverink; Norbert Stockhofe; Evert J Hensen; Johannes P M Langedijk; Robbert van der Most
Vaccine-induced immunopathology during bovine respiratory syncytial virus infection: exploring the parameters of pathogenesis.
Journal of virology 2003;77(22):12067-73.
2003: Robbert van der Most; Kaja Murali-Krishna; J Gibson Lanier; E John Wherry; Maryann T Puglielli; Joseph N Blattman; Alessandro Sette; Rafi Ahmed
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation.
Virology 2003;315(1):93-102.
2003: E John Wherry; Joseph N Blattman; Kaja Murali-Krishna; Robbert van der Most; Rafi Ahmed
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
Journal of virology 2003;77(8):4911-27.
2003: Grada M van Bleek; Martien C M Poelen; Robbert van der Most; Humphrey F Brugghe; hans timmermans; Claire J P Boog; Peter Hoogerhout; Henny G Otten; Cécile A C M van Els
Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.
Journal of virology 2003;77(2):980-8.
2003: Robbert van der Most; Kaja Murali-Krishna; Rafi Ahmed
Prolonged presence of effector-memory CD8 T cells in the central nervous system after dengue virus encephalitis.
International immunology 2003;15(1):119-25.
2002: Robbert van der Most; Laurie E Harrington; Vicki Giuggio; Patryce L Mahar; Rafi Ahmed
Yellow fever virus 17D envelope and NS3 proteins are major targets of the antiviral T cell response in mice.
Virology 2002;296(1):117-24.
2001: Maryann T Puglielli; AJ Zajac; Robbert van der Most; John Dzuris; Alessandro Sette; John D Altman; Rafi Ahmed
In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb.
Journal of virology 2001;75(11):5099-107.
2000: Robbert van der Most; Kaja Murali-Krishna; Rafi Ahmed; James H Strauss
Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response.
Journal of virology 2000;74(17):8094-101.
1999: Robbert van der Most; Jeroen Corver; James H Strauss
Mutagenesis of the RGD motif in the yellow fever virus 17D envelope protein.
Virology 1999;265(1):83-95.
1998: Robbert van der Most; Kaja Murali-Krishna; J L Whitton; Carla Oseroff; J Alexander; Scott Southwood; John Sidney; Robert W Chesnut; Alessandro Sette; Rafi Ahmed
Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice.
Virology 1998;240(1):158-67.
1997: Robbert van der Most; R J Concepcion; Carla Oseroff; J Alexander; Scott Southwood; John Sidney; Robert W Chesnut; Rafi Ahmed; Alessandro Sette
Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.
Journal of virology 1997;71(7):5110-4.
1996: Robbert van der Most; Alessandro Sette; Carla Oseroff; J Alexander; Kaja Murali-Krishna; L L Lau; Scott Southwood; John Sidney; Robert W Chesnut; M Matloubian; Rafi Ahmed
Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5543-54.
1995: G van Marle; W Luytjes; Robbert van der Most; Tahar van der Straaten; Willy Spaan
Regulation of coronavirus mRNA transcription.
Journal of virology 1995;69(12):7851-6.
1995: Robbert van der Most; W Luytjes; S Rutjes; Willy Spaan
Translation but not the encoded sequence is essential for the efficient propagation of the defective interfering RNAs of the coronavirus mouse hepatitis virus.
Journal of virology 1995;69(6):3744-51.
1995: G van Marle; Robbert van der Most; Tahar van der Straaten; W Luytjes; Willy Spaan
Regulation of transcription of coronaviruses.
Advances in experimental medicine and biology 1995;380():507-10.
1994: Robbert van der Most; R J de Groot; Willy Spaan
Subgenomic RNA synthesis directed by a synthetic defective interfering RNA of mouse hepatitis virus: a study of coronavirus transcription initiation.
Journal of virology 1994;68(6):3656-66.
1994: R de Groot; L Heijnen; Robbert van der Most; Willy Spaan
Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs.
Archives of virology. Supplementum 1994;9():221-30.
1993: Robbert van der Most; L Heijnen; Willy Spaan; R de Groot
Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs.
Advances in experimental medicine and biology 1993;342():149-54.
1992: R J de Groot; Robbert van der Most; Willy Spaan
The fitness of defective interfering murine coronavirus DI-a and its derivatives is decreased by nonsense and frameshift mutations.
Journal of virology 1992;66(10):5898-905.
1992: Robbert van der Most; L Heijnen; Willy Spaan; R J de Groot
Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs.
Nucleic acids research 1992;20(13):3375-81.
1991: Robbert van der Most; P J Bredenbeek; Willy Spaan
A domain at the 3' end of the polymerase gene is essential for encapsidation of coronavirus defective interfering RNAs.
Journal of virology 1991;65(6):3219-26.