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Joachim Herz

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Elisabeth Bouché; Timothy Catchpole; Michael Frotscher; Mark Henkemeyer; Joachim Herz; Jost Leemhuis; Petra May; Mario I Romero-Ortega; Hans H Bock
Reelin induces EphB activation.
Marco Dieckmann; Joachim Herz; Steve E Humphries; Till Koehne; Robert P Marshall; Brigitte Mueller; Michael Amling; Alexander Bartelt; Frank Timo Beil; Jackie A Cooper; Wolfgang Ruether; Andreas Niemeier
Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.
Colleen M Dewey; Joachim Herz; Brett A Johnson; Chantelle F Sephton; Basar Cenik; Gang Yu
TDP-43 aggregation in neurodegeneration: are stress granules the key?

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2013: Elisabeth Bouché; Timothy Catchpole; Michael Frotscher; Mark Henkemeyer; Joachim Herz; Jost Leemhuis; Petra May; Mario I Romero-Ortega; Hans H Bock
Reelin induces EphB activation.
Cell research 2013;23(4):473-90.
2013: Marco Dieckmann; Joachim Herz; Steve E Humphries; Till Koehne; Robert P Marshall; Brigitte Mueller; Michael Amling; Alexander Bartelt; Frank Timo Beil; Jackie A Cooper; Wolfgang Ruether; Andreas Niemeier
Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(2):236-45.
2012: Colleen M Dewey; Joachim Herz; Brett A Johnson; Chantelle F Sephton; Basar Cenik; Gang Yu
TDP-43 aggregation in neurodegeneration: are stress granules the key?
Brain research 2012;1462():16-25.
2012: David M Holtzman; Joachim Herz; Guojun Bu
Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease.
Cold Spring Harbor perspectives in medicine 2012;2(3):a006312.
2012: Daniel R Dries; Gang Yu; Joachim Herz
Extracting β-amyloid from Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(9):3199-200.
2012: Yang Du; Joachim Herz; Hoang Dinh Huynh; Alan Saghatelian; Wei Wei; Marie Yang; Yihong Wan
Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates.
Nature communications 2012;3():1008.
2011: Colleen M Dewey; Basar Cenik; Chantelle F Sephton; Daniel R Dries; Paul Mayer; Shannon K Good; Brett A Johnson; Joachim Herz; Gang Yu
TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.
Molecular and cellular biology 2011;31(5):1098-108.
2011: Chantelle F Sephton; Can Cenik; Alper Kucukural; Eric B Dammer; Basar Cenik; Yuhong Han; Colleen M Dewey; Frederick P Roth; Joachim Herz; Junmin Peng; Melissa J Moore; Gang Yu
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes.
The Journal of biological chemistry 2011;286(2):1204-15.
2011: Qiang Liu; Juan Zhang; Celina Zerbinatti; Yan Zhan; Benedict J Kolber; Joachim Herz; Louis J Muglia; Guojun Bu
Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.
PLoS biology 2011;9(1):e1000575.
2011: Sangeetha Ramesh; Craig N Morrell; Cristina Tarango; Gail D Thomas; Ivan S Yuhanna; Guillermina Girardi; Joachim Herz; Rolf T Urbanus; Philip G de Groot; Philip E Thorpe; Jane E Salmon; Philip W Shaul; Chieko Mineo
Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2.
The Journal of clinical investigation 2011;121(1):120-31.
2010: Jost Leemhuis; Elisabeth Bouché; Michael Frotscher; Frank Henle; Lutz Hein; Joachim Herz; Dieter K Meyer; Marina Pichler; Günter Roth; Carsten Schwan; Hans H Bock
Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(44):14759-72.
2010: Marco Dieckmann; Martin Frederik Dietrich; Joachim Herz
Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family.
Biological chemistry 2010;391(11):1341-63.
2010: Bianka Brunne; Shanting Zhao; Amin Derouiche; Joachim Herz; Petra May; Michael Frotscher; Hans H Bock
Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus.
Glia 2010;58(13):1553-69.
2010: Ying Chen; Murat S Durakoglugil; Xunde Xian; Joachim Herz
ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):12011-6.
2010: Courtney Karner; Martin F Dietrich; Eric B Johnson; Natalie Kappesser; Christian Tennert; Ferda Percin; Bernd Wollnik; Thomas J. Carroll; Joachim Herz
Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome.
PloS one 2010;5(4):e10418.
2010: Martin F Dietrich; Louise van der Weyden; Haydn M Prosser; Allan Bradley; Joachim Herz; David J Adams
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.
PloS one 2010;5(4):e9960.
2009: Joshua E Basford; Zachary W Q Moore; Li Zhou; Joachim Herz; David Y Hui
Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1772-8.
2009: Kym M Boycott; Carsten Bonnemann; Joachim Herz; Stephanie Neuert; Chandree Beaulieu; James N Scott; Anuradha Venkatasubramanian; Jillian S Parboosingh
Mutations in VLDLR as a cause for autosomal recessive cerebellar ataxia with mental retardation (dysequilibrium syndrome).
Journal of child neurology 2009;24(10):1310-5.
2009: Murat S Durakoglugil; Ying Chen; Charles L White; Ege T Kavalali; Joachim Herz
Reelin signaling antagonizes beta-amyloid at the synapse.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15938-43.
2009: Joachim Herz
Apolipoprotein E receptors in the nervous system.
Current opinion in lipidology 2009;20(3):190-6.
2009: Joachim Herz; Ying Chen; Irene Masiulis; Li Zhou
Expanding functions of lipoprotein receptors.
Journal of lipid research 2009;50 Suppl():S287-92.
2009: Hong Y Choi; Marco Dieckmann; Joachim Herz; Andreas Niemeier
Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo.
PloS one 2009;4(11):e7930.
2009: Li Zhou; Yoshiharu Takayama; Philippe Boucher; Michelle Tallquist; Joachim Herz
LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation.
PloS one 2009;4(9):e6922.
2009: Li Zhou; Hong Y Choi; Wei-Ping Li; Fang Xu; Joachim Herz
LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export.
PloS one 2009;4(8):e6853.
2008: Robert Lukowski; Pascal Weinmeister; Dominik Bernhard; Susanne Feil; Michael Gotthardt; Joachim Herz; Steffen Massberg; Alma Zernecke; Christian Weber; Franz Hofmann; Robert Feil
Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(7):1244-50.
2008: Joachim Herz; Kym M Boycott; Jillian S Parboosingh
"Devolution" of bipedality.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):E25.
2008: Alin L Akopians; Alex H Babayan; Uwe Beffert; Joachim Herz; Allan I Basbaum; Patricia E Phelps
Contribution of the Reelin signaling pathways to nociceptive processing.
The European journal of neuroscience 2008;27(3):523-37.
2008: Matt Larouche; Uwe Beffert; Joachim Herz; Richard Hawkes
The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.
PloS one 2008;3(2):e1653.
2007: Susanna M Hofmann; Li Zhou; Diego Perez-Tilve; Todd Greer; Erin Grant; Lauren Wancata; Andrew Thomas; Paul Pfluger; Joshua E Basford; Dean Gilham; Joachim Herz; Matthias H Tschöp; David Y Hui
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice.
The Journal of clinical investigation 2007;117(11):3271-82.
2007: Qiang Liu; Celina V Zerbinatti; Juan Zhang; Hyang-Sook Hoe; Baiping Wang; Sarah L Cole; Joachim Herz; Louis J Muglia; Guojun Bu
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.
Neuron 2007;56(1):66-78.
2007: Joachim Herz
Overview: the long and winding road to understanding Alzheimer's disease.
Neuron 2007;53(4):477-9.
2007: Philippe Boucher; Wei-Ping Li; Rachel L Matz; Yoshiharu Takayama; Johan Auwerx; Richard G W Anderson; Joachim Herz
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.
PloS one 2007;2(5):e448.
2007: Guangcheng Zhang; Amir H Assadi; Robert S McNeil; Uwe Beffert; Anthony Wynshaw-Boris; Joachim Herz; Gary D Clark; Gabriella D'Arcangelo
The Pafah1b complex interacts with the reelin receptor VLDLR.
PloS one 2007;2(2):e252.
2007: Hans H Bock; Joachim Herz; Petra May
Conditional animal models for the study of lipid metabolism and lipid disorders.
Handbook of experimental pharmacology 2007;(178):407-39.
2007: Christopher Jones; Rita Garuti; Peter Michaely; Wei-Ping Li; Nobuyo Maeda; Jonathan C Cohen; Joachim Herz; Helen H Hobbs
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia.
The Journal of clinical investigation 2007;117(1):165-74.
2006: Uwe Beffert; Farnas Nematollah Farsian; Irene Masiulis; Robert E Hammer; Sung Ok Yoon; Klaus M Giehl; Joachim Herz
ApoE receptor 2 controls neuronal survival in the adult brain.
Current biology : CB 2006;16(24):2446-52.
2006: L Hu; Lianne S M Boesten; P May; Joachim Herz; Niels Bovenschen; Menno V Huisman; Jimmy F P Berbée; Louis M Havekes; Bart J M van Vlijmen; Jouke T Tamsma
Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2710-5.
2006: Joachim Herz; Ying Chen
Reelin, lipoprotein receptors and synaptic plasticity.
Nature reviews. Neuroscience 2006;7(11):850-9.
2006: Eric B Johnson; David J Steffen; Kristen W Lynch; Joachim Herz
Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease.
Genomics 2006;88(5):600-9.
2006: Xiaobiao Li; Joachim Herz; Denis Monard
Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1.
Journal of cellular biochemistry 2006;99(3):936-51.
2006: Joachim Herz
The switch on the RAPper's necklace...
Molecular cell 2006;23(4):451-5.
2006: Chunzhang Cao; Daniel Lawrence; Yang Li; Christine A F Von Arnim; Joachim Herz; Enming Joseph Su; Alexandra Makarova; Bradley T Hyman; Dudley K Strickland; Li Zhang
Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration.
The EMBO journal 2006;25(9):1860-70.
2006: Uwe Beffert; Andre Durudas; Edwin J Weeber; Peggy C Stolt; Klaus M Giehl; J David Sweatt; Robert E Hammer; Joachim Herz
Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(7):2041-52.
2006: Suzanne Y Guénette; Yang Chang; Thomas Hiesberger; James A Richardson; Christopher B Eckman; Elizabeth A Eckman; Robert E Hammer; Joachim Herz
Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development.
The EMBO journal 2006;25(2):420-31.
2005: Rita Garuti; Christopher Jones; Wei-Ping Li; Peter Michaely; Joachim Herz; Robert D Gerard; Jonathan C Cohen; Helen H Hobbs
The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits.
The Journal of biological chemistry 2005;280(49):40996-1004.
2005: Eric B Johnson; Robert E Hammer; Joachim Herz
Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.
Human molecular genetics 2005;14(22):3523-38.
2005: Petra May; Joachim Herz; Hans H Bock
Molecular mechanisms of lipoprotein receptor signalling.
Cellular and molecular life sciences : CMLS 2005;62(19-20):2325-38.
2005: Hiroshi Kurosu; Masaya Yamamoto; Jeremy D Clark; Johanne V Pastor; Animesh Nandi; Prem Gurnani; Owen P McGuinness; Hirotaka Chikuda; Masayuki Yamaguchi; Hiroshi Kawaguchi; Iichiro Shimomura; Yoshiharu Takayama; Joachim Herz; C Ronald Kahn; Kevin P Rosenblatt; Makoto Kuro-o
Suppression of aging in mice by the hormone Klotho.
Science (New York, N.Y.) 2005;309(5742):1829-33.
2005: Ying Chen; Uwe Beffert; Mert Ertunc; Tie-Shan Tang; Ege T Kavalali; Ilya Bezprozvanny; Joachim Herz
Reelin modulates NMDA receptor activity in cortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(36):8209-16.
2005: Uwe Beffert; Edwin J Weeber; Andre Durudas; Shenfeng Qiu; Irene Masiulis; J David Sweatt; Wei-Ping Li; Giselind Adelmann; Michael Frotscher; Robert E Hammer; Joachim Herz
Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2.
Neuron 2005;47(4):567-79.
2005: Yoshiharu Takayama; Petra May; Richard G W Anderson; Joachim Herz
Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta).
The Journal of biological chemistry 2005;280(18):18504-10.
2005: Peggy C Stolt; Ying Chen; Pingsheng Liu; Hans H Bock; Stephen C Blacklow; Joachim Herz
Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction.
The Journal of biological chemistry 2005;280(10):9671-7.
2005: Hisayuki Shigematsu; Li Lin; Takao Takahashi; Masaharu Nomura; Makoto Suzuki; Ignacio I Wistuba; Kwun M Fong; Huei Lee; Shinichi Toyooka; Nobuyoshi Shimizu; Takehiko Fujisawa; Ziding Feng; Jack A Roth; Joachim Herz; John D Minna; Adi F Gazdar
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
Journal of the National Cancer Institute 2005;97(5):339-46.
2005: Aparna R Aiyer; Narimon Honarpour; Joachim Herz; Deepak Srivastava
Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype.
Developmental biology 2005;278(1):155-62.
2005: Caroline Petit-Turcotte; Nicole Aumont; Uwe Beffert; Doris Dea; Joachim Herz; Judes Poirier
The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity.
Neurobiology of aging 2005;26(2):195-206.
2004: Adi F Gazdar; Hisayuki Shigematsu; Joachim Herz; John D Minna
Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?
Trends in molecular medicine 2004;10(10):481-6.
2004: Petra May; Astrid Rohlmann; Hans H Bock; Kai Zurhove; Jamey D Marth; Eike D Schomburg; Jeffrey L Noebels; Uwe Beffert; J David Sweatt; Edwin J Weeber; Joachim Herz
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.
Molecular and cellular biology 2004;24(20):8872-83.
2004: Hans H Bock; Yves Jossin; Petra May; Oliver Bergner; Joachim Herz
Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1.
The Journal of biological chemistry 2004;279(32):33471-9.
2004: John D Minna; Adi F Gazdar; Stephen R Sprang; Joachim Herz
Cancer. A bull's eye for targeted lung cancer therapy.
Science (New York, N.Y.) 2004;304(5676):1458-61.
2004: Sonia M S Espirito Santo; Nuno M M Pires; Lianne S M Boesten; Gery Gerritsen; Niels Bovenschen; Ko Willems van Dijk; J Wouter Jukema; Hans M G Princen; André Bensadoun; Wei-Ping Li; Joachim Herz; Louis M Havekes; Bart J M van Vlijmen
Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol.
Blood 2004;103(10):3777-82.
2004: Peter Marschang; Jochen Brich; Edwin J Weeber; J David Sweatt; John M Shelton; James A Richardson; Robert E Hammer; Joachim Herz
Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.
Molecular and cellular biology 2004;24(9):3782-93.
2004: Joachim Herz; David Y Hui
Lipoprotein receptors in the vascular wall.
Current opinion in lipidology 2004;15(2):175-81.
2004: Marcel Vergés; Andre Bensadoun; Joachim Herz; John D Belcher; Richard J Havel
Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 2004;279(10):9030-6.
2004: Uwe Beffert; Peggy C Stolt; Joachim Herz
Functions of lipoprotein receptors in neurons.
Journal of lipid research 2004;45(3):403-9.
2004: Uwe Beffert; Edwin J Weeber; Gerardo Morfini; Jane Ko; Scott T Brady; Li-Huei Tsai; J David Sweatt; Joachim Herz
Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(8):1897-906.
2004: Vera Strasser; Daniela Fasching; Christoph Hauser; Harald Mayer; Hans H Bock; Thomas Hiesberger; Joachim Herz; Edwin J Weeber; J David Sweatt; Albéna Pramatarova; Brian Howell; Wolfgang J Schneider; Johannes Nimpf
Receptor clustering is involved in Reelin signaling.
Molecular and cellular biology 2004;24(3):1378-86.
2004: Yves Jossin; Nina Ignatova; Thomas Hiesberger; Joachim Herz; Catherine Lambert de Rouvroit; André M Goffinet
The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(2):514-21.
2003: Joachim Herz
LRP: a bright beacon at the blood-brain barrier.
The Journal of clinical investigation 2003;112(10):1483-5.
2003: Amir H Assadi; Guangcheng Zhang; Uwe Beffert; Robert S McNeil; Amy Renfro; Sanyong Niu; Carlo C Quattrocchi; Barbara Antalffy; Michael Sheldon; Dawna Duncan Armstrong; Anthony Wynshaw-Boris; Joachim Herz; Gabriella D'Arcangelo; Gary D Clark
Interaction of reelin signaling and Lis1 in brain development.
Nature genetics 2003;35(3):270-6.
2003: Hans H Bock; Yves Jossin; Pingsheng Liu; Eckart Förster; Petra May; André M Goffinet; Joachim Herz
Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination.
The Journal of biological chemistry 2003;278(40):38772-9.
2003: Eva Hartfuss; Eckart Förster; Hans H Bock; Michael A Hack; Pierre Leprince; Juan M Luque; Joachim Herz; Michael Frotscher; Magdalena Götz
Reelin signaling directly affects radial glia morphology and biochemical maturation.
Development (Cambridge, England) 2003;130(19):4597-609.
2003: Petra May; Hans H Bock; Johannes Nimpf; Joachim Herz
Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.
The Journal of biological chemistry 2003;278(39):37386-92.
2003: Christopher Jones; Robert E Hammer; Wei-Ping Li; Jonathan C Cohen; Helen H Hobbs; Joachim Herz
Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.
The Journal of biological chemistry 2003;278(31):29024-30.
2003: Olav M Andersen; Ching-Hei Yeung; Henrik Vorum; Maren Wellner; Thomas K Andreassen; Bettina Erdmann; Eva-Christina Mueller; Joachim Herz; Albrecht Otto; Trevor G Cooper; Thomas E Willnow
Essential role of the apolipoprotein E receptor-2 in sperm development.
The Journal of biological chemistry 2003;278(26):23989-95.
2003: Karl Heinz Weiss; Celine Johanssen; Albrecht Tielsch; Joachim Herz; Thomas Deller; Michael Frotscher; Eckart Förster
Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice.
The Journal of comparative neurology 2003;460(1):56-65.
2003: Marc-Estienne Roehrich; Vincent Mooser; Vincent Lenain; Joachim Herz; Johannes Nimpf; Salman Azhar; Martine Bideau; Alessandro M Capponi; Pascal Nicod; Jacques-Antoine Haefliger; Gérard Waeber
Insulin-secreting beta-cell dysfunction induced by human lipoproteins.
The Journal of biological chemistry 2003;278(20):18368-75.
2003: Niels Bovenschen; Joachim Herz; Jos M Grimbergen; Peter J Lenting; Louis M Havekes; Koen Mertens; Bart J M van Vlijmen
Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency.
Blood 2003;101(10):3933-9.
2003: Peggy C Stolt; Hyesung Jeon; Hyun Kyu Song; Joachim Herz; Michael J Eck; Stephen C Blacklow
Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes.
Structure (London, England : 1993) 2003;11(5):569-79.
2003: Petra May; Joachim Herz
LDL receptor-related proteins in neurodevelopment.
Traffic (Copenhagen, Denmark) 2003;4(5):291-301.
2003: Philippe Boucher; Michael Gotthardt; Wei-Ping Li; Richard G W Anderson; Joachim Herz
LRP: role in vascular wall integrity and protection from atherosclerosis.
Science (New York, N.Y.) 2003;300(5617):329-32.
2003: Petra May; Hans H Bock; Joachim Herz
Integration of endocytosis and signal transduction by lipoprotein receptors.
Science's STKE : signal transduction knowledge environment 2003;2003(176):PE12.
2003: Michael Gotthardt; Robert E Hammer; Norbert Hübner; Jan Monti; Christian C Witt; Mark McNabb; James A Richardson; Henk Granzier; Siegfried Labeit; Joachim Herz
Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
The Journal of biological chemistry 2003;278(8):6059-65.
2003: Joachim Herz; Peter Marschang
Coaxing the LDL receptor family into the fold.
Cell 2003;112(3):289-92.
2003: Peter Marschang; Joachim Herz
Mouse models as tools for dissecting disorders of lipoprotein metabolism.
Seminars in cell & developmental biology 2003;14(1):25-35.
2003: Hans H Bock; Joachim Herz
Reelin activates SRC family tyrosine kinases in neurons.
Current biology : CB 2003;13(1):18-26.
2003: Jochen Brich; Feng-Shiun Shie; Brian Howell; Renhua Li; Katalin Tus; Edward K Wakeland; Lee-Way Jin; Marc C Mumby; Gary Churchill; Joachim Herz; Jonathan A Cooper
Genetic modulation of tau phosphorylation in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(1):187-92.
2002: Uwe Beffert; Gerardo Morfini; Hans H Bock; Huichuan Reyna; Scott T Brady; Joachim Herz
Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta.
The Journal of biological chemistry 2002;277(51):49958-64.
2002: Edwin J Weeber; Uwe Beffert; Chris Jones; Jill M Christian; Eckart Forster; J David Sweatt; Joachim Herz
Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning.
The Journal of biological chemistry 2002;277(42):39944-52.
2002: Alexander Drakew; Thomas Deller; Bernd Heimrich; Carl Gebhardt; Domenico Del Turco; Albrecht Tielsch; Eckart Förster; Joachim Herz; Michael Frotscher
Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice.
Experimental neurology 2002;176(1):12-24.
2002: Petra May; Y Krishna Reddy; Joachim Herz
Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain.
The Journal of biological chemistry 2002;277(21):18736-43.
2002: Rita Holtwick; Michael Gotthardt; Boris Skryabin; Martin Steinmetz; Regine Potthast; Bernd Zetsche; Robert E Hammer; Joachim Herz; Michaela Kuhn
Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7142-7.
2002: Philippe Boucher; Pingsheng Liu; Michael Gotthardt; Thomas Hiesberger; Richard G W Anderson; Joachim Herz
Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.
The Journal of biological chemistry 2002;277(18):15507-13.
2002: Carl Gebhardt; Domenico Del Turco; Alexander Drakew; Albrecht Tielsch; Joachim Herz; Michael Frotscher; Thomas Deller
Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice.
The Journal of comparative neurology 2002;445(3):278-92.
2002: Joachim Herz; Hans H Bock
Lipoprotein receptors in the nervous system.
Annual review of biochemistry 2002;71():405-34.
2001: Joachim Herz; Dudley K Strickland
LRP: a multifunctional scavenger and signaling receptor.
The Journal of clinical investigation 2001;108(6):779-84.
2001: Narimon Honarpour; Sandra L Gilbert; Bruce T Lahn; Xinhe Wang; Joachim Herz
Apaf-1 deficiency and neural tube closure defects are found in fog mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9683-7.
2001: Joachim Herz
Deconstructing the LDL receptor--a rhapsody in pieces.
Nature structural biology 2001;8(6):476-8.
2001: Joachim Herz
Lipoprotein receptors: beacons to neurons?
Trends in neurosciences 2001;24(4):193-5.
2001: Joachim Herz
The LDL receptor gene family: (un)expected signal transducers in the brain.
Neuron 2001;29(3):571-81.
2001: Brian Howell; Joachim Herz
The LDL receptor gene family: signaling functions during development.
Current opinion in neurobiology 2001;11(1):74-81.
2001: Narimon Honarpour; K Tabuchi; J M Stark; Robert E Hammer; Thomas C Südhof; Luis F Parada; Xinhe Wang; James A Richardson; Joachim Herz
Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1.
Neuroscience 2001;106(2):263-74.
2000: Joachim Herz; Uwe Beffert
Apolipoprotein E receptors: linking brain development and Alzheimer's disease.
Nature reviews. Neuroscience 2000;1(1):51-8.
2000: Walter Stockinger; Christian Brandes; Daniela Fasching; Marcela Hermann; Michael Gotthardt; Joachim Herz; Wolfgang J Schneider; Johannes Nimpf
The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2.
The Journal of biological chemistry 2000;275(33):25625-32.
2000: Michael Gotthardt; M Trommsdorff; M F Nevitt; John Shelton; James A Richardson; Walter Stockinger; Johannes Nimpf; Joachim Herz
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.
The Journal of biological chemistry 2000;275(33):25616-24.
2000: Joachim Herz; Michael Gotthardt; Thomas E Willnow
Cellular signalling by lipoprotein receptors.
Current opinion in lipidology 2000;11(2):161-6.
2000: P Marshall; A Rohlmann; Victor Nussenzweig; Joachim Herz; Photini Sinnis
Plasmodium sporozoites invade cells with targeted deletions in the LDL receptor related protein.
Molecular and biochemical parasitology 2000;106(2):293-8.
2000: Narimon Honarpour; C Du; James A Richardson; Robert E Hammer; Xinhe Wang; Joachim Herz
Adult Apaf-1-deficient mice exhibit male infertility.
Developmental biology 2000;218(2):248-58.
1999: Bart J M van Vlijmen; A Rohlmann; S T Page; André Bensadoun; I S Bos; Theo Van berkel; Louis M Havekes; Joachim Herz
An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins.
The Journal of biological chemistry 1999;274(49):35219-26.
1999: Thomas Hiesberger; M Trommsdorff; Brian Howell; André M Goffinet; Marc C Mumby; J A Cooper; Joachim Herz
Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation.
Neuron 1999;24(2):481-9.
1999: Thomas E Willnow; Anders Nykjaer; Joachim Herz
Lipoprotein receptors: new roles for ancient proteins.
Nature cell biology 1999;1(6):E157-62.
1999: A Sato; Y Shimada; Joachim Herz; T Yamamoto; Hisato Jingami
39-kDa receptor-associated protein (RAP) facilitates secretion and ligand binding of extracellular region of very-low-density-lipoprotein receptor: implications for a distinct pathway from low-density-lipoprotein receptor.
The Biochemical journal 1999;341 ( Pt 2)():377-83.
1999: M Trommsdorff; Michael Gotthardt; Thomas Hiesberger; John Shelton; Walter Stockinger; Johannes Nimpf; Robert E Hammer; James A Richardson; Joachim Herz
Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.
Cell 1999;97(6):689-701.
1999: Anders Nykjaer; D Dragun; D Walther; Henrik Vorum; Christian Jacobsen; Joachim Herz; F Melsen; Erik I Christensen; Thomas E Willnow
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3.
Cell 1999;96(4):507-15.
1999: Joachim Herz; R V Farese
The LDL receptor gene family, apolipoprotein B and cholesterol in embryonic development.
The Journal of nutrition 1999;129(2S Suppl):473S-475S.
1999: B J van Vlijmen; Joachim Herz
Gene targets and approaches for raising HDL.
Circulation 1999;99(1):12-4.
1998: M Trommsdorff; Jean-Paul Borg; Benjamin L Margolis; Joachim Herz
Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.
The Journal of biological chemistry 1998;273(50):33556-60.
1998: Murielle Véniant; CH Zlot; Rosemary Walzem; V Pierotti; Robert Driscoll; David A Dichek; Joachim Herz; Stephen G Young
Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice.
The Journal of clinical investigation 1998;102(8):1559-68.
1998: Thomas Hiesberger; S Hüttler; A Rohlmann; W Schneider; K Sandhoff; Joachim Herz
Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).
The EMBO journal 1998;17(16):4617-25.
1998: Robert V Farese; Joachim Herz
Cholesterol metabolism and embryogenesis.
Trends in genetics : TIG 1998;14(3):115-20.
1998: A Rohlmann; Michael Gotthardt; Robert E Hammer; Joachim Herz
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.
The Journal of clinical investigation 1998;101(3):689-95.
1997: D Storm; Joachim Herz; PK Trinder; Michael Loos
C1 inhibitor-C1s complexes are internalized and degraded by the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1997;272(49):31043-50.
1997: Attilio Rigotti; Bernardo L Trigatti; Marsha Penman; Helen Rayburn; Joachim Herz; Monty Krieger
A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12610-5.
1997: H Shimano; Iichiro Shimomura; Robert E Hammer; Joachim Herz; Joseph L Goldstein; Michael S Brown; Jay D Horton
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.
The Journal of clinical investigation 1997;100(8):2115-24.
1997: Michael S Brown; Joachim Herz; Joseph L Goldstein
LDL-receptor structure. Calcium cages, acid baths and recycling receptors.
Nature 1997;388(6643):629-30.
1997: Christian Brandes; S Novak; Walter Stockinger; Joachim Herz; Wolfgang J Schneider; Johannes Nimpf
Avian and murine LR8B and human apolipoprotein E receptor 2: differentially spliced products from corresponding genes.
Genomics 1997;42(2):185-91.
1997: R C Johnson; SM Chapman; ZM Dong; Jose Ordovas; Tanya N Mayadas; Joachim Herz; Richard O Hynes; Ernst Schaefer; Denisa D Wagner
Absence of P-selectin delays fatty streak formation in mice.
The Journal of clinical investigation 1997;99(5):1037-43.
1997: Joachim Herz; Thomas E Willnow; R V Farese
Cholesterol, hedgehog and embryogenesis.
Nature genetics 1997;15(2):123-4.
1996: V L Meiner; Sylvaine Cases; Heather M Myers; E Sande; Stefano Bellosta; M Schambelan; Robert E Pitas; J McGuire; Joachim Herz; Robert V Farese
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14041-6.
1996: A Rohlmann; Michael Gotthardt; Thomas E Willnow; Robert E Hammer; Joachim Herz
Sustained somatic gene inactivation by viral transfer of Cre recombinase.
Nature biotechnology 1996;14(11):1562-5.
1996: I Warshawsky; Joachim Herz; George J Broze; Alan L Schwartz
The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis.
The Journal of biological chemistry 1996;271(42):25873-9.
1996: Photini Sinnis; Thomas E Willnow; Marcelo RS Briones; Joachim Herz; Victor Nussenzweig
Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.
The Journal of experimental medicine 1996;184(3):945-54.
1996: J R Braun; Thomas E Willnow; S Ishibashi; G Ashwell; Joachim Herz
The major subunit of the asialoglycoprotein receptor is expressed on the hepatocellular surface in mice lacking the minor receptor subunit.
The Journal of biological chemistry 1996;271(35):21160-6.
1996: Thomas E Willnow; Jan Hilpert; Scott A Armstrong; A Rohlmann; Robert E Hammer; DK Burns; Joachim Herz
Defective forebrain development in mice lacking gp330/megalin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8460-4.
1996: Margrit Schwarz; Erik G Lund; Kenneth D R Setchell; H J Kayden; Joseph E Zerwekh; I Björkhem; Joachim Herz; David W Russell
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.
The Journal of biological chemistry 1996;271(30):18024-31.
1996: S Ishibashi; Margrit Schwarz; Philip Frykman; Joachim Herz; David W Russell
Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.
The Journal of biological chemistry 1996;271(30):18017-23.
1996: Thomas E Willnow; A Rohlmann; J Horton; H Otani; J R Braun; Robert E Hammer; Joachim Herz
RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors.
The EMBO journal 1996;15(11):2632-9.
1996: E Sehayek; X X Wang; Israel Vlodavsky; R Avner; Hana Levkovitz; Thomas Olivecrona; G Olivecrona; Thomas E Willnow; Joachim Herz; S Eisenberg
Heparan sulfate-dependent and low density lipoprotein receptor-related protein-dependent catabolic pathways for lipoprotein lipase in mouse embryonic fibroblasts.
Israel journal of medical sciences 1996;32(6):449-54.
1996: Thomas E Willnow; J M Moehring; N M Inocencio; T J Moehring; Joachim Herz
The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro.
The Biochemical journal 1996;313 ( Pt 1)():71-6.
1995: Laura A Woollett; Y Osono; Joachim Herz; John M Dietschy
Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12500-4.
1995: Joachim Herz; Thomas E Willnow
Gene transfer and disruption strategies to elucidate hepatic lipoprotein receptor functions.
Atherosclerosis 1995;118 Suppl():S37-41.
1995: M Narita; Guojun Bu; G M Olins; D A Higuchi; Joachim Herz; George J Broze; Alan L Schwartz
Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo.
The Journal of biological chemistry 1995;270(42):24800-4.
1995: Philip Frykman; Michael S Brown; T Yamamoto; Joseph L Goldstein; Joachim Herz
Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8453-7.
1995: M Narita; Guojun Bu; Joachim Herz; Alan L Schwartz
Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo.
The Journal of clinical investigation 1995;96(2):1164-8.
1995: T W Rosahl; D Spillane; Markus Missler; Joachim Herz; D K Selig; J R Wolff; Robert E Hammer; Robert C Malenka; Thomas C Südhof
Essential functions of synapsins I and II in synaptic vesicle regulation.
Nature 1995;375(6531):488-93.
1995: Joachim Herz; S Q Qiu; A Oesterle; H V DeSilva; S Shafi; R J Havel
Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4611-5.
1995: Thomas E Willnow; Scott A Armstrong; Robert E Hammer; Joachim Herz
Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4537-41.
1995: Thomas E Willnow; Joachim Herz
Animal models for disorders of hepatic lipoprotein metabolism.
Journal of molecular medicine (Berlin, Germany) 1995;73(5):213-20.
1995: Joachim Herz; Thomas E Willnow
Lipoprotein and receptor interactions in vivo.
Current opinion in lipidology 1995;6(2):97-103.
1995: Y Osono; Laura A Woollett; Joachim Herz; John M Dietschy
Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse.
The Journal of clinical investigation 1995;95(3):1124-32.
1995: Wolfgang Poller; Thomas E Willnow; Jan Hilpert; Joachim Herz
Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1995;270(6):2841-5.
1994: S Ishibashi; Robert E Hammer; Joachim Herz
Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit.
The Journal of biological chemistry 1994;269(45):27803-6.
1994: Joachim Herz; Thomas E Willnow
Functions of the LDL receptor gene family.
Annals of the New York Academy of Sciences 1994;737():14-9.
1994: K Orth; Thomas E Willnow; Joachim Herz; Mary-Jane Gething; J Sambrook
Low density lipoprotein receptor-related protein is necessary for the internalization of both tissue-type plasminogen activator-inhibitor complexes and free tissue-type plasminogen activator.
The Journal of biological chemistry 1994;269(33):21117-22.
1994: Thomas E Willnow; Z Sheng; S Ishibashi; Joachim Herz
Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist.
Science (New York, N.Y.) 1994;264(5164):1471-4.
1994: Thomas E Willnow; K Orth; Joachim Herz
Molecular dissection of ligand binding sites on the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1994;269(22):15827-32.
1994: S Ishibashi; Joachim Herz; Nobuyo Maeda; Joseph L Goldstein; Michael S Brown
The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4431-5.
1994: H Mokuno; S Brady; Leila Kotite; Joachim Herz; Richard J Havel
Effect of the 39-kDa receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in the rat.
The Journal of biological chemistry 1994;269(18):13238-43.
1994: S Ishibashi; Joseph L Goldstein; Michael S Brown; Joachim Herz; DK Burns
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice.
The Journal of clinical investigation 1994;93(5):1885-93.
1994: Thomas E Willnow; Joachim Herz
Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A. Evidence that this protein is required for uptake and degradation of multiple ligands.
Journal of cell science 1994;107 ( Pt 3)():719-26.
1994: Monty Krieger; Joachim Herz
Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).
Annual review of biochemistry 1994;63():601-37.
1994: Thomas E Willnow; Joachim Herz
Homologous recombination for gene replacement in mouse cell lines.
Methods in cell biology 1994;43 Pt A():305-34.
1993: T W Rosahl; Martin Geppert; D Spillane; Joachim Herz; Robert E Hammer; Robert C Malenka; Thomas C Südhof
Short-term synaptic plasticity is altered in mice lacking synapsin I.
Cell 1993;75(4):661-70.
1993: S Ishibashi; Michael S Brown; Joseph L Goldstein; Robert D Gerard; Robert E Hammer; Joachim Herz
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
The Journal of clinical investigation 1993;92(2):883-93.
1993: Joachim Herz; Robert D Gerard
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2812-6.
1993: O Descamps; D Bilheimer; Joachim Herz
Insulin stimulates receptor-mediated uptake of apoE-enriched lipoproteins and activated alpha 2-macroglobulin in adipocytes.
The Journal of biological chemistry 1993;268(2):974-81.
1992: Thomas E Willnow; Joseph L Goldstein; K Orth; Michael S Brown; Joachim Herz
Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.
The Journal of biological chemistry 1992;267(36):26172-80.
1992: Joachim Herz; David E Clouthier; Robert E Hammer
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.
Cell 1992;71(3):411-21.
1992: K Orth; Edwin L Madison; Mary-Jane Gething; J F Sambrook; Joachim Herz
Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7422-6.
1991: Joachim Herz; Joseph L Goldstein; Dudley K Strickland; Y K Ho; Michael S Brown
39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
The Journal of biological chemistry 1991;266(31):21232-8.
1990: Karl H Weisgraber; Robert W Mahley; Robert C Kowal; Joachim Herz; Joseph L Goldstein; Michael S Brown
Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1990;265(36):22453-9.
1990: Joachim Herz; N Flint; K Stanley; R Frank; Bernhard Dobberstein
The 68 kDa protein of signal recognition particle contains a glycine-rich region also found in certain RNA-binding proteins.
FEBS letters 1990;276(1-2):103-7.
1990: Joachim Herz; Robert C Kowal; Y K Ho; Michael S Brown; Joseph L Goldstein
Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver.
The Journal of biological chemistry 1990;265(34):21355-62.
1990: Dirk Görlich; Siegfried Prehn; E Hartmann; Joachim Herz; Albrecht Otto; R Kraft; M Wiedmann; Siegne Knespel; Bernhard Dobberstein; Tom A Rapoport
The signal sequence receptor has a second subunit and is part of a translocation complex in the endoplasmic reticulum as probed by bifunctional reagents.
The Journal of cell biology 1990;111(6 Pt 1):2283-94.
1990: Robert C Kowal; Joachim Herz; Karl H Weisgraber; Robert W Mahley; Michael S Brown; Joseph L Goldstein
Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1990;265(18):10771-9.
1990: Joachim Herz; Robert C Kowal; Joseph L Goldstein; Michael S Brown
Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.
The EMBO journal 1990;9(6):1769-76.
1990: Siegfried Prehn; Joachim Herz; E Hartmann; T V Kurzchalia; R Frank; K Roemisch; Bernhard Dobberstein; Tom A Rapoport
Structure and biosynthesis of the signal-sequence receptor.
European journal of biochemistry / FEBS 1990;188(2):439-45.
1989: H Kütt; Joachim Herz; K K Stanley
Structure of the low-density lipoprotein receptor-related protein (LRP) promoter.
Biochimica et biophysica acta 1989;1009(3):229-36.
1989: Ulrike Beisiegel; W Weber; G Ihrke; Joachim Herz; K K Stanley
The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein.
Nature 1989;341(6238):162-4.
1989: K Römisch; J Webb; Joachim Herz; Siegfried Prehn; R Frank; M Vingron; Bernhard Dobberstein
Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains.
Nature 1989;340(6233):478-82.
1989: Robert C Kowal; Joachim Herz; Joseph L Goldstein; Victoria Esser; Michael S Brown
Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(15):5810-4.
1989: Ola Myklebost; K Arheden; S Rogne; A Geurts van Kessel; N Mandahl; Joachim Herz; K Stanley; S Heim; F Mitelman
The gene for the human putative apoE receptor is on chromosome 12 in the segment q13-14.
Genomics 1989;5(1):65-9.
1988: Joachim Herz; U Hamann; S Rogne; Ola Myklebost; H Gausepohl; K K Stanley
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.
The EMBO journal 1988;7(13):4119-27.
1988: Doris Koesling; Joachim Herz; H Gausepohl; F Niroomand; Klaus-Dieter Hinsch; A Mülsch; E Böhme; Günter Schultz; R Frank
The primary structure of the 70 kDa subunit of bovine soluble guanylate cyclase.
FEBS letters 1988;239(1):29-34.
1988: K K Stanley; Joachim Herz; H Haymerle
Constructing expression cDNA libraries using unphosphorylated adaptors.
Methods in molecular biology (Clifton, N.J.) 1988;4():319-28.
1988: D Jenne; C Rey; D Masson; K K Stanley; Joachim Herz; G Plaetinck; Jürg Tschopp
cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(1):318-23.
1987: K K Stanley; Joachim Herz
Topological mapping of complement component C9 by recombinant DNA techniques suggests a novel mechanism for its insertion into target membranes.
The EMBO journal 1987;6(7):1951-7.
1986: H Haymerle; Joachim Herz; Giorgio M Bressan; R Frank; K K Stanley
Efficient construction of cDNA libraries in plasmid expression vectors using an adaptor strategy.
Nucleic acids research 1986;14(21):8615-24.
1984: E Böhme; G Grossmann; Joachim Herz; A Mülsch; C Spies; G Schultz
Regulation of cyclic GMP formation by soluble guanylate cyclase: stimulation by NO-containing compounds.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():259-66.