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Guojun Bu

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Physiology

Endocytosis

Living Beings

Anatomy

Phenomena

Protein Binding

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Co-Publications
Name
32
Schwartz, Alan
23
Li, Yonghe
16
Holtzman, David
13
Marzolo, María-Paz
9
van Kerkhof, Peter
9
Zerbinatti, Celina
8
Cam, Judy
7
Ladu, Mary Jo
7
Lu, Wenyan
6
Strous, Ger
5
Fagan, Anne
4
Getz, Godfrey
4
Knisely, Jane
4
McCormick, Lynn
4
Reardon-Alulis, Catherine

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Publications

TOP 3
Song Heesang; Bu Guojun
MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1.
Hoe Hyang-Sook; Lee Kea Joo; Carney Rosalind S E; Lee Jiyeon; Markova Alexandra; Lee Ji-Yun; Howell Brian W; Hyman Bradley T; Pak Daniel T S; Bu Guojun; Rebeck G William
Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.
Woodley David T; Fan Jianhua; Cheng Chieh-Fang; Li Yong; Chen Mei; Bu Guojun; Li Wei
Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.

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All Publications

2009: Song Heesang; Bu Guojun
MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1.
Biochemical and biophysical research communications 2009;388(2):400-5.
2009: Hoe Hyang-Sook; Lee Kea Joo; Carney Rosalind S E; Lee Jiyeon; Markova Alexandra; Lee Ji-Yun; Howell Brian W; Hyman Bradley T; Pak Daniel T S; Bu Guojun; Rebeck G William
Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(23):7459-73.
2009: Woodley David T; Fan Jianhua; Cheng Chieh-Fang; Li Yong; Chen Mei; Bu Guojun; Li Wei
Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.
Journal of cell science 2009;122(Pt 10):1495-8.
2009: Bu Guojun
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy.
Nature reviews. Neuroscience 2009;10(5):333-44.
2009: Liu Chia-Chen; Pearson Chelsea; Bu Guojun
Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains.
The Journal of biological chemistry 2009;284(22):15299-307.
2009: Marzolo Maria-Paz; Bu Guojun
Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease.
Seminars in cell & developmental biology 2009;20(2):191-200.
2009: Hayashi Shuji; Yamamoto Masaki; Tachibana Katsuhiro; Ueno Yushi; Bu Guojun; Fukushima Takeo
Mechanism of photofrin-enhanced ultrasound-induced human glioma cell death.
Anticancer research 2009;29(3):897-905.
2009: Song Heesang; Li Yonghe; Lee Jiyeon; Schwartz Alan L; Bu Guojun
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.
Cancer research 2009;69(3):879-86.
2009: Donoso Maribel; Cancino Jorge; Lee Jiyeon; van Kerkhof Peter; Retamal Claudio; Bu Guojun; Gonzalez Alfonso; Cáceres Alfredo; Marzolo María-Paz
Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways.
Molecular biology of the cell 2009;20(1):481-97.
2009: Zhang Yunwu; Owens Lisa; Bu Guojun
Meeting report: 2009 international conference on molecular neurodegeneration May 18-20, 2009, Xiamen, China.
Molecular neurodegeneration 2009;4():43.
2009: Liu Qiang; Zhang Juan; Tran Hien; Verbeek Marcel M; Reiss Karina; Estus Steven; Bu Guojun
LRP1 shedding in human brain: roles of ADAM10 and ADAM17.
Molecular neurodegeneration 2009;4():17.
2008: Yamada Kaoru; Hashimoto Tadafumi; Yabuki Chiori; Nagae Yusuke; Tachikawa Masanori; Strickland Dudley K; Liu Qiang; Bu Guojun; Basak Jacob M; Holtzman David M; Ohtsuki Sumio; Terasaki Tetsuya; Iwatsubo Takeshi
The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid beta peptides in an in vitro model of the blood-brain barrier cells.
The Journal of biological chemistry 2008;283(50):34554-62.
2008: Doray Balraj; Knisely Jane M; Wartman Lukas; Bu Guojun; Kornfeld Stuart
Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2.
Traffic (Copenhagen, Denmark) 2008;9(9):1551-62.
2008: Bu Guojun; Lu Wenyan; Liu Chia-Chen; Selander Katri; Yoneda Toshiyuki; Hall Christopher; Keller Evan T; Li Yonghe
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases.
International journal of cancer. Journal international du cancer 2008;123(5):1034-42.
2008: Cirrito John R; Kang Jae-Eun; Lee Jiyeon; Stewart Floy R; Verges Deborah K; Silverio Luz M; Bu Guojun; Mennerick Steven; Holtzman David M
Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo.
Neuron 2008;58(1):42-51.
2008: Lee Jiyeon; Retamal Claudio; Cuitiño Loreto; Caruano-Yzermans Amy; Shin Jung-Eun; van Kerkhof Peter; Marzolo Maria-Paz; Bu Guojun
Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.
The Journal of biological chemistry 2008;283(17):11501-8.
2008: Parkyn Celia J; Vermeulen Esmeralda G M; Mootoosamy Roy C; Sunyach Claire; Jacobsen Christian; Oxvig Claus; Moestrup Søren; Liu Qiang; Bu Guojun; Jen Angela; Morris Roger J
LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein.
Journal of cell science 2008;121(Pt 6):773-83.
2008: Hu Kebin; Lin Ling; Tan Xiaoyue; Yang Junwei; Bu Guojun; Mars Wendy M; Liu Youhua
tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis.
Journal of the American Society of Nephrology : JASN 2008;19(3):503-14.
2008: Knisely Jane M; Lee Jiyeon; Bu Guojun
Measurement of receptor endocytosis and recycling.
Methods in molecular biology (Clifton, N.J.) 2008;457():319-32.
2007: Wilhelmus Micha M M; Otte-Höller Irene; van Triel Jos J J; Veerhuis Robert; Maat-Schieman Marion L C; Bu Guojun; de Waal Robert M W; Verbeek Marcel M
Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells.
The American journal of pathology 2007;171(6):1989-99.
2007: Chen Sen; Bu Guojun; Takei Yoshifumi; Sakamoto Kazuma; Ikematsu Shinya; Muramatsu Takashi; Kadomatsu Kenji
Midkine and LDL-receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells.
Journal of cell science 2007;120(Pt 22):4009-15.
2007: Liu Qiang; Zerbinatti Celina V; Zhang Juan; Hoe Hyang-Sook; Wang Baiping; Cole Sarah L; Herz Joachim; Muglia Louis; Bu Guojun
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.
Neuron 2007;56(1):66-78.
2007: Knisely Jane M; Li Yonghe; Griffith Janice M; Geuze Hans J; Schwartz Alan L; Bu Guojun
Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.
Experimental cell research 2007;313(15):3298-307.
2007: Yuseff María Isabel; Farfan Pamela; Bu Guojun; Marzolo María-Paz
A cytoplasmic PPPSP motif determines megalin's phosphorylation and regulates receptor's recycling and surface expression.
Traffic (Copenhagen, Denmark) 2007;8(9):1215-30.
2007: Chen Jianglei; Bu Guojun; Wang Jianjun
A complete NMR spectral assignment of the conserved region of the MESD protein, MESD(12-155).
Biomolecular NMR assignments 2007;1(1):3-5.
2007: Doray Balraj; Lee Intaek; Knisely Jane; Bu Guojun; Kornfeld Stuart
The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.
Molecular biology of the cell 2007;18(5):1887-96.
2007: Fuentealba Rodrigo A; Barría Maria Ines; Lee Jiyeon; Cam Judy; Araya Claudia; Escudero Claudia A; Inestrosa Nibaldo C; Bronfman Francisca C; Bu Guojun; Marzolo Maria-Paz
ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.
Molecular neurodegeneration 2007;2():14.
2006: Bu Guojun; Cam Judy; Zerbinatti Celina
LRP in amyloid-beta production and metabolism.
Annals of the New York Academy of Sciences 2006;1086():35-53.
2006: Zerbinatti Celina V; Wahrle Suzanne E; Kim Hyungjin; Cam Judy A; Bales Kelly; Paul Steven M; Holtzman David M; Bu Guojun
Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice.
The Journal of biological chemistry 2006;281(47):36180-6.
2006: Li Yonghe; Lu Wenyan; He Xi; Bu Guojun
Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.
FEBS letters 2006;580(22):5423-8.
2006: Knisely Jane M; Bu Guojun
Genetics and molecular biology: motive studies in mice--two NPXY motifs in the intracellular domain of lipoprotein receptor-related protein 1 exhibit differential importance during fetal development.
Current opinion in lipidology 2006;17(4):480-2.
2006: Marzolo María-Paz; Bu Guojun
Morphogens, new passengers on lipoprotein particles.
Current opinion in lipidology 2006;17(2):202-4.
2006: Lisi Simonetta; Botta Roberta; Pinchera Aldo; Collins A Bernard; Refetoff Samuel; Arvan Peter; Bu Guojun; Grasso Lucia; Marshansky Vladimir; Bechoua Shaliha; Hurtado-Lorenzo Andres; Marcocci Claudio; Brown Dennis; McCluskey Robert T; Marinò Michele
Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
American journal of physiology. Cell physiology 2006;290(4):C1160-7.
2006: LaDu Mary Jo; Stine W Blaine; Narita Masaaki; Getz Godfrey S; Reardon Catherine A; Bu Guojun
Self-assembly of HEK cell-secreted ApoE particles resembles ApoE enrichment of lipoproteins as a ligand for the LDL receptor-related protein.
Biochemistry 2006;45(2):381-90.
2006: Bi Guo-Qiang; Bolshakov Vadim; Bu Guojun; Cahill Catherine M; Chen Zhou-Feng; Collingridge Graham L; Cooper Robin L; Coorssen Jens R; El-Husseini Alaa; Galhardo Vasco; Gan Wen-Biao; Gu Jianguo; Inoue Kazuhide; Isaac John; Iwata Koichi; Jia Zhengping; Kaang Bong-Kiun; Kawamata Mikito; Kida Satoshi; Klann Eric; Kohno Tatsuro; Li Min; Li Xiao-Jiang; MacDonald John F; Nader Karim; Nguyen Peter V; Oh Uhtaek; Ren Ke; Roder John C; Salter Michael W; Song Weihong; Sugita Shuzo; Tang Shao-Jun; Tao Yuanxiang; Wang Yu Tian; Woo Newton; Woodin Melanie A; Yan Zhen; Yoshimura Megumu; Xu Ming; Xu Zao C; Zhang Xia; Zhen Mei; Zhuo Min
Recent advances in basic neurosciences and brain disease: from synapses to behavior.
Molecular pain 2006;2():38.
2006: Rebeck G William; LaDu Mary Jo; Estus Steven; Bu Guojun; Weeber Edwin J
The generation and function of soluble apoE receptors in the CNS.
Molecular neurodegeneration 2006;1():15.
2006: Cam Judy A; Bu Guojun
Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.
Molecular neurodegeneration 2006;1():8.
2005: Wu Long-Jun; Toyoda Hiroki; Zhao Ming-Gao; Lee Yong-Seok; Tang Jianrong; Ko Shanelle W; Jia Yong Heng; Shum Fanny W F; Zerbinatti Celina V; Bu Guojun; Wei Feng; Xu Tian-Le; Muglia Louis J; Chen Zhou-Feng; Auberson Yves P; Kaang Bong-Kiun; Zhuo Min
Upregulation of forebrain NMDA NR2B receptors contributes to behavioral sensitization after inflammation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(48):11107-16.
2005: Li Yonghe; Chen Jianglei; Lu Wenyan; McCormick Lynn M; Wang Jianjun; Bu Guojun
Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.
Journal of cell science 2005;118(Pt 22):5305-14.
2005: Li Yonghe; Bu Guojun
LRP5/6 in Wnt signaling and tumorigenesis.
Future oncology (London, England) 2005;1(5):673-81.
2005: Cuitino Loreto; Matute Ricardo; Retamal Claudio; Bu Guojun; Inestrosa Nibaldo C; Marzolo María-Paz
ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.
Traffic (Copenhagen, Denmark) 2005;6(9):820-38.
2005: Pastrana Diana V; Hanson Alison J; Knisely Jane; Bu Guojun; Fitzgerald David J
LRP 1 B functions as a receptor for Pseudomonas exotoxin.
Biochimica et biophysica acta 2005;1741(3):234-9.
2005: van Kerkhof Peter; Lee Jiyeon; McCormick Lynn; Tetrault Elena; Lu Wenyan; Schoenfish Marissa; Oorschot Viola; Strous Ger J; Klumperman Judith; Bu Guojun
Sorting nexin 17 facilitates LRP recycling in the early endosome.
The EMBO journal 2005;24(16):2851-61.
2005: Li Yonghe; Lu Wenyan; Bu Guojun
Striking differences of LDL receptor-related protein 1B expression in mouse and human.
Biochemical and biophysical research communications 2005;333(3):868-73.
2005: Fryer John D; Demattos Ronald B; McCormick Lynn M; O'Dell Mark A; Spinner Michael L; Bales Kelly R; Paul Steven M; Sullivan Patrick M; Parsadanian Maia; Bu Guojun; Holtzman David M
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
The Journal of biological chemistry 2005;280(27):25754-9.
2005: Green Pattie S; Bales Kelly; Paul Steven; Bu Guojun
Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease.
Endocrinology 2005;146(6):2774-81.
2005: Benchenane Karim; Berezowski Vincent; Ali Carine; Fernández-Monreal Mónica; López-Atalaya José P; Brillault Julien; Chuquet Julien; Nouvelot André; MacKenzie Eric T; Bu Guojun; Cecchelli Roméo; Touzani Omar; Vivien Denis
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis.
Circulation 2005;111(17):2241-9.
2005: McCormick Lynn M; Urade Reiko; Arakaki Yukino; Schwartz Alan L; Bu Guojun
Independent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein.
Biochemistry 2005;44(15):5794-803.
2005: Cam Judy A; Zerbinatti Celina V; Li Yonghe; Bu Guojun
Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
The Journal of biological chemistry 2005;280(15):15464-70.
2005: Lee Jiyeon; Bu Guojun
Genetics and molecular biology: ABCA1 in brain apolipoprotein E metabolism and lipidation.
Current opinion in lipidology 2005;16(1):115-7.
2005: Zerbinatti Celina V; Bu Guojun
LRP and Alzheimer's disease.
Reviews in the neurosciences 2005;16(2):123-35.
2004: Li Yonghe; Lu Wenyan; He Xi; Schwartz Alan L; Bu Guojun
LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution.
Oncogene 2004;23(56):9129-35.
2004: Pan Weihong; Kastin Abba J; Zankel Todd C; van Kerkhof Peter; Terasaki Tetsuya; Bu Guojun
Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier.
Journal of cell science 2004;117(Pt 21):5071-8.
2004: Prince William S; McCormick Lynn M; Wendt Dan J; Fitzpatrick Paul A; Schwartz Keri L; Aguilera Allora I; Koppaka Vishwanath; Christianson Terri M; Vellard Michel C; Pavloff Nadine; Lemontt Jeff F; Qin Minmin; Starr Chris M; Bu Guojun; Zankel Todd C
Lipoprotein receptor binding, cellular uptake, and lysosomal delivery of fusions between the receptor-associated protein (RAP) and alpha-L-iduronidase or acid alpha-glucosidase.
The Journal of biological chemistry 2004;279(33):35037-46.
2004: Cam Judy A; Zerbinatti Celina V; Knisely Jane M; Hecimovic Silva; Li Yonghe; Bu Guojun
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
The Journal of biological chemistry 2004;279(28):29639-46.
2004: Li Yonghe; Bu Guojun
LRP5, a multifunctional cell surface receptor.
Current opinion in lipidology 2004;15(3):361-3.
2004: Li Yonghe; Lu Wenyan; Schwartz Alan L; Bu Guojun
Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.
Journal of lipid research 2004;45(6):1084-91.
2004: Fernández-Monreal Mónica; López-Atalaya José P; Benchenane Karim; Léveillé Frederic; Cacquevel Mathias; Plawinski Laurent; MacKenzie Eric T; Bu Guojun; Buisson Alain; Vivien Denis
Is tissue-type plasminogen activator a neuromodulator?
Molecular and cellular neurosciences 2004;25(4):594-601.
2004: Zerbinatti Celina V; Wozniak David F; Cirrito John; Cam Judy A; Osaka Hiroshi; Bales Kelly R; Zhuo Min; Paul Steven M; Holtzman David M; Bu Guojun
Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(4):1075-80.
2003: Li Yonghe; Lu Wenyan; Bu Guojun
Essential role of the low density lipoprotein receptor-related protein in vascular smooth muscle cell migration.
FEBS letters 2003;555(2):346-50.
2003: Knisely Jane M; Bu Guojun
Genetics and molecular biology.
Current opinion in lipidology 2003;14(4):401-3.
2003: Marzolo María-Paz; Yuseff María Isabel; Retamal Claudio; Donoso Maribel; Ezquer Fernando; Farfán Pamela; Li Yonghe; Bu Guojun
Differential distribution of low-density lipoprotein-receptor-related protein (LRP) and megalin in polarized epithelial cells is determined by their cytoplasmic domains.
Traffic (Copenhagen, Denmark) 2003;4(4):273-88.
2002: Shirotani-Ikejima Hiroko; Kokame Koichi; Hamuro Tsutomu; Bu Guojun; Kato Hisao; Miyata Toshiyuki
Tissue factor pathway inhibitor induces expression of JUNB and GADD45B mRNAs.
Biochemical and biophysical research communications 2002;299(5):847-52.
2002: Narita Masaaki; Holtzman David M; Fagan Anne M; LaDu Mary Jo; Yu Li; Han Xianlin; Gross Richard W; Bu Guojun; Schwartz Alan L
Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.
Journal of biochemistry 2002;132(5):743-9.
2002: Li Yonghe; Knisely Jane M; Lu Wenyan; McCormick Lynn M; Wang Jieyi; Henkin Jack; Schwartz Alan L; Bu Guojun
Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.
The Journal of biological chemistry 2002;277(44):42366-71.
2002: Green Pattie S; Bu Guojun
Genetics and molecular biology: phosphorylation of low-density lipoprotein receptor-related protein by platelet-derived growth factor.
Current opinion in lipidology 2002;13(5):569-72.
2002: Shibata Yoshihisa; Muramatsu Takashi; Hirai Makoto; Inui Tatsuya; Kimura Terutoshi; Saito Hidehiko; McCormick Lynn M; Bu Guojun; Kadomatsu Kenji
Nuclear targeting by the growth factor midkine.
Molecular and cellular biology 2002;22(19):6788-96.
2002: Melman Lora; Geuze Hans J; Li Yonghe; McCormick Lynn M; Van Kerkhof Peter; Strous Ger J; Schwartz Alan L; Bu Guojun
Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.
Molecular biology of the cell 2002;13(9):3325-35.
2002: Gent Jürgen; van Kerkhof Peter; Roza Marcel; Bu Guojun; Strous Ger J
Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9858-63.
2002: Li Yonghe; Lu Wenyan; Schwartz Alan L; Bu Guojun
Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants.
Biochemistry 2002;41(15):4921-8.
2002: Su Hua Poo; Nakada-Tsukui Kumiko; Tosello-Trampont Annie-Carole; Li Yonghe; Bu Guojun; Henson Peter M; Ravichandran Kodimangalam S
Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).
The Journal of biological chemistry 2002;277(14):11772-9.
2002: Swertfeger Debi K; Bu Guojun; Hui David Y
Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration.
The Journal of biological chemistry 2002;277(6):4141-6.
2001: LaDu M J; Shah J A; Reardon C A; Getz G S; Bu G; Hu J; Guo L; Van Eldik L J
Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses.
Neurochemistry international 2001;39(5-6):427-34.
2001: van Kerkhof P; Alves dos Santos C M; Sachse M; Klumperman J; Bu G; Strous G J
Proteasome inhibitors block a late step in lysosomal transport of selected membrane but not soluble proteins.
Molecular biology of the cell 2001;12(8):2556-66.
2001: Liu C X; Li Y; Obermoeller-McCormick L M; Schwartz A L; Bu G
The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein.
The Journal of biological chemistry 2001;276(31):28889-96.
2001: Melman L; Cao Z F; Rennke S; Marzolo M P; Wardell M R; Bu G
High affinity binding of receptor-associated protein to heparin and low density lipoprotein receptor-related protein requires similar basic amino acid sequence motifs.
The Journal of biological chemistry 2001;276(31):29338-46.
2001: Li Y; Lu W; Marzolo M P; Bu G
Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates.
The Journal of biological chemistry 2001;276(21):18000-6.
2001: Obermoeller-McCormick L M; Li Y; Osaka H; FitzGerald D J; Schwartz A L; Bu G
Dissection of receptor folding and ligand-binding property with functional minireceptors of LDL receptor-related protein.
Journal of cell science 2001;114(Pt 5):899-908.
2001: Li Y; Cam J; Bu G
Low-density lipoprotein receptor family: endocytosis and signal transduction.
Molecular neurobiology 2001;23(1):53-67.
2001: Zerbinatti C; Bu G
Bimonthly update. Genetics and molecular biology.
Current opinion in lipidology 2001;12(1):77-9.
2001: Li Y; van Kerkhof P; Marzolo M P; Strous G J; Bu G
Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptor-related protein: implication for receptor-mediated endocytosis.
Molecular and cellular biology 2001;21(4):1185-95.
2001: Bu G
The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family.
International review of cytology 2001;209():79-116.
2000: Liu Y; Jones M; Hingtgen C M; Bu G; Laribee N; Tanzi R E; Moir R D; Nath A; He J J
Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands.
Nature medicine 2000;6(12):1380-7.
2000: LaDu M J; Shah J A; Reardon C A; Getz G S; Bu G; Hu J; Guo L; van Eldik L J
Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures.
The Journal of biological chemistry 2000;275(43):33974-80.
2000: Li Y; Marzolo M P; van Kerkhof P; Strous G J; Bu G
The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein.
The Journal of biological chemistry 2000;275(22):17187-94.
2000: Bu G; Marzolo M P
Role of rap in the biogenesis of lipoprotein receptors.
Trends in cardiovascular medicine 2000;10(4):148-55.
2000: Marzolo M P; von Bernhardi R; Bu G; Inestrosa N C
Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells.
Journal of neuroscience research 2000;60(3):401-11.
2000: Ladu M J; Reardon C; Van Eldik L; Fagan A M; Bu G; Holtzman D; Getz G S
Lipoproteins in the central nervous system.
Annals of the New York Academy of Sciences 2000;903():167-75.
2000: Zhuo M; Holtzman D M; Li Y; Osaka H; DeMaro J; Jacquin M; Bu G
Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(2):542-9.
1999: Li Y; Bu G
Genetics and molecular biology.
Current opinion in lipidology 1999;10(6):627-9.
1999: Savonen R; Obermoeller L M; Trausch-Azar J S; Schwartz A L; Bu G
The carboxyl-terminal domain of receptor-associated protein facilitates proper folding and trafficking of the very low density lipoprotein receptor by interaction with the three amino-terminal ligand-binding repeats of the receptor.
The Journal of biological chemistry 1999;274(36):25877-82.
1999: Moulder K L; Narita M; Chang L K; Bu G; Johnson E M
Analysis of a novel mechanism of neuronal toxicity produced by an apolipoprotein E-derived peptide.
Journal of neurochemistry 1999;72(3):1069-80.
1999: Hamik A; Setiadi H; Bu G; McEver R P; Morrissey J H
Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1999;274(8):4962-9.
1998: Rall S C; Ye P; Bu G; Wardell M R
The domain structure of human receptor-associated protein. Protease sensitivity and guanidine HCl denaturation.
The Journal of biological chemistry 1998;273(37):24152-7.
1998: Obermoeller L M; Chen Z; Schwartz A L; Bu G
Ca2+ and receptor-associated protein are independently required for proper folding and disulfide bond formation of the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1998;273(35):22374-81.
1998: Bu G; Schwartz A L
RAP, a novel type of ER chaperone.
Trends in cell biology 1998;8(7):272-6.
1998: Fagan A M; Murphy B A; Patel S N; Kilbridge J F; Mobley W C; Bu G; Holtzman D M
Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury.
Experimental neurology 1998;151(2):314-25.
1998: Bu G; Sun Y; Schwartz A L; Holtzman D M
Nerve growth factor induces rapid increases in functional cell surface low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1998;273(21):13359-65.
1998: Sun Y; Wu S; Bu G; Onifade M K; Patel S N; LaDu M J; Fagan A M; Holtzman D M
Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3261-72.
1998: Bu G
Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family.
Current opinion in lipidology 1998;9(2):149-55.
1997: Narita M; Holtzman D M; Schwartz A L; Bu G
Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.
Journal of neurochemistry 1997;69(5):1904-11.
1997: Obermoeller L M; Warshawsky I; Wardell M R; Bu G
Differential functions of triplicated repeats suggest two independent roles for the receptor-associated protein as a molecular chaperone.
The Journal of biological chemistry 1997;272(16):10761-8.
1997: Farhangrazi Z S; Ying H; Bu G; Dugan L L; Fagan A M; Choi D W; Holtzman D M
High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.
Neuroreport 1997;8(5):1127-30.
1997: Hardy M M; Feder J; Wolfe R A; Bu G
Low density lipoprotein receptor-related protein modulates the expression of tissue-type plasminogen activator in human colon fibroblasts.
The Journal of biological chemistry 1997;272(10):6812-7.
1997: Narita M; Bu G; Holtzman D M; Schwartz A L
The low-density lipoprotein receptor-related protein, a multifunctional apolipoprotein E receptor, modulates hippocampal neurite development.
Journal of neurochemistry 1997;68(2):587-95.
1997: Bu G; Rennke S; Geuze H J
ERD2 proteins mediate ER retention of the HNEL signal of LRP's receptor-associated protein (RAP).
Journal of cell science 1997;110 ( Pt 1)():65-73.
1996: Fagan A M; Bu G; Sun Y; Daugherty A; Holtzman D M
Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1996;271(47):30121-5.
1996: Bu G; Rennke S
Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1996;271(36):22218-24.
1995: Holtzman D M; Pitas R E; Kilbridge J; Nathan B; Mahley R W; Bu G; Schwartz A L
Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9480-4.
1995: Narita M; Bu G; Olins G M; Higuchi D A; Herz J; Broze G J; Schwartz A L
Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo.
The Journal of biological chemistry 1995;270(42):24800-4.
1995: Narita M; Bu G; Herz J; Schwartz A L
Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo.
The Journal of clinical investigation 1995;96(2):1164-8.
1995: Vettenranta K; Bu G; Schwartz A L
Binding and endocytosis of 39 kDa protein by MDBK cells.
Journal of cellular physiology 1995;164(2):441-7.
1995: Bu G; Geuze H J; Strous G J; Schwartz A L
39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.
The EMBO journal 1995;14(10):2269-80.
1995: Warshawsky I; Bu G; Mast A; Saffitz J E; Broze G J; Schwartz A L
The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo.
The Journal of clinical investigation 1995;95(4):1773-81.
1995: Warshawsky I; Bu G; Schwartz A L
Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein.
Biochemistry 1995;34(10):3404-15.
1994: Bu G; Maksymovitch E A; Geuze H; Schwartz A L
Subcellular localization and endocytic function of low density lipoprotein receptor-related protein in human glioblastoma cells.
The Journal of biological chemistry 1994;269(47):29874-82.
1994: Warshawsky I; Bu G; Schwartz A L
LRP and the receptor-mediated endocytosis of plasminogen activators.
Annals of the New York Academy of Sciences 1994;737():70-87.
1994: Warshawsky I; Bu G; Schwartz A L
Identification of domains on the 39-kDa protein that inhibit the binding of ligands to the low density lipoprotein receptor--related protein.
Annals of the New York Academy of Sciences 1994;737():514-7.
1994: Bu G; Maksymovitch E A; Nerbonne J M; Schwartz A L
Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons.
The Journal of biological chemistry 1994;269(28):18521-8.
1994: Bu G; Warshawsky I; Schwartz A L
Cellular receptors for the plasminogen activators.
Blood 1994;83(12):3427-36.
1994: Warshawsky I; Bu G; Schwartz A L
Binding analysis of amino-terminal and carboxyl-terminal regions of the 39-kDa protein to the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1994;269(5):3325-30.
1993: Iadonato S P; Bu G; Maksymovitch E A; Schwartz A L
Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells.
The Biochemical journal 1993;296 ( Pt 3)():867-75.
1993: Warshawsky I; Bu G; Schwartz A L
Identification of domains on the 39-kDa protein that inhibit the binding of ligands to the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1993;268(29):22046-54.
1993: Warshawsky I; Bu G; Schwartz A L
39-kD protein inhibits tissue-type plasminogen activator clearance in vivo.
The Journal of clinical investigation 1993;92(2):937-44.
1993: Bu G; Maksymovitch E A; Schwartz A L
Receptor-mediated endocytosis of tissue-type plasminogen activator by low density lipoprotein receptor-related protein on human hepatoma HepG2 cells.
The Journal of biological chemistry 1993;268(17):13002-9.
1992: Bu G; Williams S; Strickland D K; Schwartz A L
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7427-31.
1992: Bu G; Morton P A; Schwartz A L
Identification and partial characterization by chemical cross-linking of a binding protein for tissue-type plasminogen activator (t-PA) on rat hepatoma cells. A plasminogen activator inhibitor type 1-independent t-PA receptor.
The Journal of biological chemistry 1992;267(22):15595-602.

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