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Bernd Nilius

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Ion Channel Gating

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Publications

TOP 3
Nilius Bernd
Polycystins under pressure.
Talavera Karel; Gees Maarten; Karashima Yuji; Meseguer Víctor M; Vanoirbeek Jeroen A J; Damann Nils; Everaerts Wouter; Benoit Melissa; Janssens Annelies; Vennekens Rudi; Viana Félix; Nemery Benoit; Nilius Bernd; Voets Thomas
Nicotine activates the chemosensory cation channel TRPA1.
Vriens Joris; Appendino Giovanni; Nilius Bernd
Pharmacology of vanilloid transient receptor potential cation channels.

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All Publications

2009: Nilius Bernd
Polycystins under pressure.
Cell 2009;139(3):466-7.
2009: Talavera Karel; Gees Maarten; Karashima Yuji; Meseguer Víctor M; Vanoirbeek Jeroen A J; Damann Nils; Everaerts Wouter; Benoit Melissa; Janssens Annelies; Vennekens Rudi; Viana Félix; Nemery Benoit; Nilius Bernd; Voets Thomas
Nicotine activates the chemosensory cation channel TRPA1.
Nature neuroscience 2009;12(10):1293-9.
2009: Vriens Joris; Appendino Giovanni; Nilius Bernd
Pharmacology of vanilloid transient receptor potential cation channels.
Molecular pharmacology 2009;75(6):1262-79.
2009: Klausen Thomas Kjaer; Pagani Alberto; Minassi Alberto; Ech-Chahad Abdellah; Prenen Jean; Owsianik Grzegorz; Hoffmann Else Kay; Pedersen Stine Falsig; Appendino Giovanni; Nilius Bernd
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study.
Journal of medicinal chemistry 2009;52(9):2933-9.
2009: Hutchings Graham; Gevaert Thomas; Deprest Jan; Nilius Bernd; Williams Olivia; De Ridder Dirk
The effect of extracellular adenosine triphosphate on the spontaneous contractility of human myometrial strips.
European journal of obstetrics, gynecology, and reproductive biology 2009;143(2):79-83.
2009: Everaerts Wouter; Sepúlveda M Rosario; Gevaert Thomas; Roskams Tania; Nilius Bernd; De Ridder Dirk
Where is TRPV1 expressed in the bladder, do we see the real channel?
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(4):421-5.
2009: Shimizu Takahiro; Owsianik Grzegorz; Freichel Marc; Flockerzi Veit; Nilius Bernd; Vennekens Rudi
TRPM4 regulates migration of mast cells in mice.
Cell calcium 2009;45(3):226-32.
2009: Shimizu Takahiro; Janssens Annelies; Voets Thomas; Nilius Bernd
Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume.
Pflügers Archiv : European journal of physiology 2009;457(4):795-807.
2009: Karashima Yuji; Talavera Karel; Everaerts Wouter; Janssens Annelies; Kwan Kelvin Y; Vennekens Rudi; Nilius Bernd; Voets Thomas
TRPA1 acts as a cold sensor in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1273-8.
2009: Voets Thomas; Nilius Bernd
TRPCs, GPCRs and the Bayliss effect.
The EMBO journal 2009;28(1):4-5.
2009: Damann N; Owsianik G; Li S; Poll C; Nilius B
The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils.
Acta physiologica (Oxford, England) 2009;195(1):3-11.
2008: Nilius Bernd; Voets Thomas
A TRP channel-steroid marriage.
Nature cell biology 2008;10(12):1383-4.
2008: Loot Annemarieke E; Popp Rüdiger; Fisslthaler Beate; Vriens Joris; Nilius Bernd; Fleming Ingrid
Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation.
Cardiovascular research 2008;80(3):445-52.
2008: Nilius Bernd; Owsianik Grzegorz; Voets Thomas
Transient receptor potential channels meet phosphoinositides.
The EMBO journal 2008;27(21):2809-16.
2008: Fabian A; Fortmann T; Dieterich P; Riethmüller C; Schön P; Mally S; Nilius B; Schwab A
TRPC1 channels regulate directionality of migrating cells.
Pflügers Archiv : European journal of physiology 2008;457(2):475-84.
2008: Karashima Yuji; Prenen Jean; Meseguer Victor; Owsianik Grzegorz; Voets Thomas; Nilius Bernd
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators.
Pflügers Archiv : European journal of physiology 2008;457(1):77-89.
2008: Damann Nils; Voets Thomas; Nilius Bernd
TRPs in our senses.
Current biology : CB 2008;18(18):R880-9.
2008: Masuyama Ritsuko; Vriens Joris; Voets Thomas; Karashima Yuji; Owsianik Grzegorz; Vennekens Rudi; Lieben Liesbet; Torrekens Sophie; Moermans Karen; Vanden Bosch An; Bouillon Roger; Nilius Bernd; Carmeliet Geert
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts.
Cell metabolism 2008;8(3):257-65.
2008: Köttgen Michael; Buchholz Björn; Garcia-Gonzalez Miguel A; Kotsis Fruzsina; Fu Xiao; Doerken Mara; Boehlke Christopher; Steffl Daniel; Tauber Robert; Wegierski Tomasz; Nitschke Roland; Suzuki Makoto; Kramer-Zucker Albrecht; Germino Gregory G; Watnick Terry; Prenen Jean; Nilius Bernd; Kuehn E Wolfgang; Walz Gerd
TRPP2 and TRPV4 form a polymodal sensory channel complex.
The Journal of cell biology 2008;182(3):437-47.
2008: Rock Matthew J; Prenen Jean; Funari Vincent A; Funari Tara L; Merriman Barry; Nelson Stanley F; Lachman Ralph S; Wilcox William R; Reyno Soraya; Quadrelli Roberto; Vaglio Alicia; Owsianik Grzegorz; Janssens Annelies; Voets Thomas; Ikegawa Shiro; Nagai Toshiro; Rimoin David L; Nilius Bernd; Cohn Daniel H
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia.
Nature genetics 2008;40(8):999-1003.
2008: Wondergem Robert; Ecay Tom W; Mahieu Frank; Owsianik Grzegorz; Nilius Bernd
HGF/SF and menthol increase human glioblastoma cell calcium and migration.
Biochemical and biophysical research communications 2008;372(1):210-5.
2008: Talavera Karel; Nilius Bernd; Voets Thomas
Neuronal TRP channels: thermometers, pathfinders and life-savers.
Trends in neurosciences 2008;31(6):287-95.
2008: Sharif-Naeini Reza; Dedman Alexandra; Folgering Joost H A; Duprat Fabrice; Patel Amanda; Nilius Bernd; Honoré Eric
TRP channels and mechanosensory transduction: insights into the arterial myogenic response.
Pflügers Archiv : European journal of physiology 2008;456(3):529-40.
2008: Talavera Karel; Yasumatsu Keiko; Yoshida Ryusuke; Margolskee Robert F; Voets Thomas; Ninomiya Yuzo; Nilius Bernd
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1343-55.
2008: Dewachter I; Ris L; Croes S; Borghgraef P; Devijver H; Voets T; Nilius B; Godaux E; Van Leuven F
Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
Neurobiology of aging 2008;29(5):639-52.
2008: Vriens Joris; Nilius Bernd; Vennekens Rudi
Herbal Compounds and Toxins Modulating TRP Channels.
Current neuropharmacology 2008;6(1):79-96.
2008: D'hoedt Dieter; Owsianik Grzegorz; Prenen Jean; Cuajungco Math Pham; Grimm Christian; Heller Stefan; Voets Thomas; Nilius Bernd
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3.
The Journal of biological chemistry 2008;283(10):6272-80.
2008: Wilkinson Jenny A; Scragg Jason L; Boyle John P; Nilius Bernd; Peers Chris
H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death.
Pflügers Archiv : European journal of physiology 2008;455(6):1141-51.
2008: Saliez J; Bouzin C; Rath G; Ghisdal P; Desjardins F; Rezzani R; Rodella L F; Vriens J; Nilius B; Feron O; Balligand J-L; Dessy C
Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.
Circulation 2008;117(8):1065-74.
2008: Meseguer Victor; Karashima Yuji; Talavera Karel; D'Hoedt Dieter; Donovan-Rodríguez Tansy; Viana Felix; Nilius Bernd; Voets Thomas
Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(3):576-86.
2008: Hutchings Graham; Gevaert Thomas; Deprest Jan; Roskams Tania; Van Lommel Alfons; Nilius Bernd; De Ridder Dirk
Immunohistochemistry using an antibody to unphosphorylated connexin 43 to identify human myometrial interstitial cells.
Reproductive biology and endocrinology : RB&E 2008;6():43.
2008: Hughes David A; Tang Kun; Strotmann Rainer; Schöneberg Torsten; Prenen Jean; Nilius Bernd; Stoneking Mark
Parallel selection on TRPV6 in human populations.
PloS one 2008;3(2):e1686.
2008: Vennekens Rudi; Owsianik Grzegorz; Nilius Bernd
Vanilloid transient receptor potential cation channels: an overview.
Current pharmaceutical design 2008;14(1):18-31.
2008: Hutchings G; Gevaert T; Deprest J; Nilius B; De Ridder D
Effect of prolonged c-kit receptor inhibition by imatinib mesylate on the uterine contractility of pregnant rabbits.
Gynecologic and obstetric investigation 2008;65(2):108-11.
2008: Everaerts Wouter; Gevaert Thomas; Nilius Bernd; De Ridder Dirk
On the origin of bladder sensing: Tr(i)ps in urology.
Neurourology and urodynamics 2008;27(4):264-73.
2007: Gevaert Thomas; Vriens Joris; Segal Andrei; Everaerts Wouter; Roskams Tania; Talavera Karel; Owsianik Grzegorz; Liedtke Wolfgang; Daelemans Dirk; Dewachter Ilse; Van Leuven Fred; Voets Thomas; De Ridder Dirk; Nilius Bernd
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
The Journal of clinical investigation 2007;117(11):3453-62.
2007: Logothetis Diomedes E; Nilius Bernd
Dynamic changes in phosphoinositide levels control ion channel activity.
Pflügers Archiv : European journal of physiology 2007;455(1):1-3.
2007: Rohacs Tibor; Nilius Bernd
Regulation of transient receptor potential (TRP) channels by phosphoinositides.
Pflügers Archiv : European journal of physiology 2007;455(1):157-68.
2007: Karashima Yuji; Damann Nils; Prenen Jean; Talavera Karel; Segal Andrei; Voets Thomas; Nilius Bernd
Bimodal action of menthol on the transient receptor potential channel TRPA1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(37):9874-84.
2007: Voets Thomas; Nilius Bernd
Modulation of TRPs by PIPs.
The Journal of physiology 2007;582(Pt 3):939-44.
2007: Nilius Bernd
TRP channels in disease.
Biochimica et biophysica acta 2007;1772(8):805-12.
2007: Nilius Bernd; Voets Thomas
Neurophysiology: channelling cold reception.
Nature 2007;448(7150):147-8.
2007: Waning J; Vriens J; Owsianik G; Stüwe L; Mally S; Fabian A; Frippiat C; Nilius B; Schwab A
A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migration.
Cell calcium 2007;42(1):17-25.
2007: Topala Catalin N; Groenestege Wouter Tiel; Thébault Stéphanie; van den Berg Dennis; Nilius Bernd; Hoenderop Joost G; Bindels René J
Molecular determinants of permeation through the cation channel TRPM6.
Cell calcium 2007;41(6):513-23.
2007: Vriens Joris; Owsianik Grzegorz; Janssens Annelies; Voets Thomas; Nilius Bernd
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4.
The Journal of biological chemistry 2007;282(17):12796-803.
2007: Voets Thomas; Owsianik Grzegorz; Janssens Annelies; Talavera Karel; Nilius Bernd
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli.
Nature chemical biology 2007;3(3):174-82.
2007: Vennekens Rudi; Olausson Jenny; Meissner Marcel; Bloch Wilhelm; Mathar Ilka; Philipp Stephan E; Schmitz Frank; Weissgerber Petra; Nilius Bernd; Flockerzi Veit; Freichel Marc
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4.
Nature immunology 2007;8(3):312-20.
2007: Nilius B; Mahieu F; Karashima Y; Voets T
Regulation of TRP channels: a voltage-lipid connection.
Biochemical Society transactions 2007;35(Pt 1):105-8.
2007: Talavera K; Ninomiya Y; Winkel C; Voets T; Nilius B
Influence of temperature on taste perception.
Cellular and molecular life sciences : CMLS 2007;64(4):377-81.
2007: Mahieu Frank; Owsianik Grzegorz; Verbert Leen; Janssens Annelies; De Smedt Humbert; Nilius Bernd; Voets Thomas
TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
The Journal of biological chemistry 2007;282(5):3325-36.
2007: Nilius Bernd; Owsianik Grzegorz; Voets Thomas; Peters John A
Transient receptor potential cation channels in disease.
Physiological reviews 2007;87(1):165-217.
2007: Nilius Bernd
Transient receptor potential (TRP) cation channels: rewarding unique proteins.
Bulletin et mémoires de l'Académie royale de médecine de Belgique 2007;162(3-4):244-53.
2007: Pedersen Stine Falsig; Nilius Bernd
Transient receptor potential channels in mechanosensing and cell volume regulation.
Methods in enzymology 2007;428():183-207.
2007: Gevaert Thomas; Vandepitte Joachim; Hutchings Graham; Vriens Joris; Nilius Bernd; De Ridder Dirk
TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.
Neurourology and urodynamics 2007;26(3):440-50; discussion 451-3.
2007: Voets T; Owsianik G; Nilius B
TRPM8.
Handbook of experimental pharmacology 2007;(179):329-44.
2007: Vennekens R; Nilius B
Insights into TRPM4 function, regulation and physiological role.
Handbook of experimental pharmacology 2007;(179):269-85.
2007: Gevaert Thomas; Vandepitte Joachim; Ost Dieter; Nilius Bernd; De Ridder Dirk
Autonomous contractile activity in the isolated rat bladder is modulated by a TRPV1 dependent mechanism.
Neurourology and urodynamics 2007;26(3):424-32; discussion 451-3.
2006: Nilius Bernd; Vennekens Rudi
From cardiac cation channels to the molecular dissection of the transient receptor potential channel TRPM4.
Pflügers Archiv : European journal of physiology 2006;453(3):313-21.
2006: Talavera Karel; Nilius Bernd
Evidence for common structural determinants of activation and inactivation in T-type Ca2+ channels.
Pflügers Archiv : European journal of physiology 2006;453(2):189-201.
2006: Nilius Bernd; Talavera Karel; Verkhratsky Alexei
T-type calcium channels: the never ending story.
Cell calcium 2006;40(2):81-8.
2006: Talavera Karel; Nilius Bernd
Biophysics and structure-function relationship of T-type Ca2+ channels.
Cell calcium 2006;40(2):97-114.
2006: Lambers Tim T; Mahieu Frank; Oancea Elena; Hoofd Louis; de Lange Frank; Mensenkamp Arjen R; Voets Thomas; Nilius Bernd; Clapham David E; Hoenderop Joost G; Bindels René J
Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.
The EMBO journal 2006;25(13):2978-88.
2006: Cuajungco Math P; Grimm Christian; Oshima Kazuo; D'hoedt Dieter; Nilius Bernd; Mensenkamp Arjen R; Bindels René J M; Plomann Markus; Heller Stefan
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.
The Journal of biological chemistry 2006;281(27):18753-62.
2006: Nilius Bernd; Mahieu Frank
A road map for TR(I)Ps.
Molecular cell 2006;22(3):297-307.
2006: Ullrich Nina; Caplanusi Adrian; Brône Bert; Hermans Diane; Larivière Els; Nilius Bernd; Van Driessche Willy; Eggermont Jan
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells.
American journal of physiology. Cell physiology 2006;290(5):C1287-96.
2006: Nilius Bernd; Mahieu Frank; Prenen Jean; Janssens Annelies; Owsianik Grzegorz; Vennekens Rudi; Voets Thomas
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.
The EMBO journal 2006;25(3):467-78.
2006: Owsianik G; D'hoedt D; Voets T; Nilius B
Structure-function relationship of the TRP channel superfamily.
Reviews of physiology, biochemistry and pharmacology 2006;156():61-90.
2006: Hutchings G; Deprest J; Nilius B; Roskams T; De Ridder D
The effect of imatinib mesylate on the contractility of isolated rabbit myometrial strips.
Gynecologic and obstetric investigation 2006;62(2):79-83.
2006: Owsianik Grzegorz; Talavera Karel; Voets Thomas; Nilius Bernd
Permeation and selectivity of TRP channels.
Annual review of physiology 2006;68():685-717.
2005: Talavera Karel; Yasumatsu Keiko; Voets Thomas; Droogmans Guy; Shigemura Noriatsu; Ninomiya Yuzo; Margolskee Robert F; Nilius Bernd
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.
Nature 2005;438(7070):1022-5.
2005: Vriens J; Owsianik G; Fisslthaler B; Suzuki M; Janssens A; Voets T; Morisseau C; Hammock B D; Fleming I; Busse R; Nilius B
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium.
Circulation research 2005;97(9):908-15.
2005: Nilius Bernd; Voets Thomas
TRP channels: a TR(I)P through a world of multifunctional cation channels.
Pflügers Archiv : European journal of physiology 2005;451(1):1-10.
2005: Pedersen Stine Falsig; Owsianik Grzegorz; Nilius Bernd
TRP channels: an overview.
Cell calcium 2005;38(3-4):233-52.
2005: Nilius Bernd; Voets Thomas; Peters John
TRP channels in disease.
Science's STKE : signal transduction knowledge environment 2005;2005(295):re8.
2005: Nilius Bernd; Talavera Karel; Owsianik Grzegorz; Prenen Jean; Droogmans Guy; Voets Thomas
Gating of TRP channels: a voltage connection?
The Journal of physiology 2005;567(Pt 1):35-44.
2005: Voets Thomas; Talavera Karel; Owsianik Grzegorz; Nilius Bernd
Sensing with TRP channels.
Nature chemical biology 2005;1(2):85-92.
2005: Vastiau Annick; Cao Lishuang; Jaspers Martine; Owsianik Grzegorz; Janssens Veerle; Cuppens Harry; Goris Jozef; Nilius Bernd; Cassiman Jean-Jacques
Interaction of the protein phosphatase 2A with the regulatory domain of the cystic fibrosis transmembrane conductance regulator channel.
FEBS letters 2005;579(16):3392-6.
2005: Cao Lishuang; Owsianik Grzegorz; Becq Frédéric; Nilius Bernd
Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells.
Biochemical and biophysical research communications 2005;331(2):503-11.
2005: Nilius Bernd; Prenen Jean; Janssens Annelies; Owsianik Grzegorz; Wang Chunbo; Zhu Michael X; Voets Thomas
The selectivity filter of the cation channel TRPM4.
The Journal of biological chemistry 2005;280(24):22899-906.
2005: Ullrich Nina D; Voets Thomas; Prenen Jean; Vennekens Rudi; Talavera Karel; Droogmans Guy; Nilius Bernd
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.
Cell calcium 2005;37(3):267-78.
2005: Nilius Bernd; Prenen Jean; Tang Jisen; Wang Chunbo; Owsianik Grzegorz; Janssens Annelies; Voets Thomas; Zhu Michael X
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.
The Journal of biological chemistry 2005;280(8):6423-33.
2005: Hoenderop Joost G J; Nilius Bernd; Bindels René J M
Calcium absorption across epithelia.
Physiological reviews 2005;85(1):373-422.
2004: Vriens Joris; Owsianik Grzegorz; Voets Thomas; Droogmans Guy; Nilius Bernd
Invertebrate TRP proteins as functional models for mammalian channels.
Pflügers Archiv : European journal of physiology 2004;449(3):213-26.
2004: Nilius Bernd; Prenen Jean; Janssens Annelies; Voets Thomas; Droogmans Guy
Decavanadate modulates gating of TRPM4 cation channels.
The Journal of physiology 2004;560(Pt 3):753-65.
2004: Talavera Karel; Staes Mik; Janssens Annelies; Droogmans Guy; Nilius Bernd
Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2004;124(3):225-38.
2004: Voets Thomas; Droogmans Guy; Wissenbach Ulrich; Janssens Annelies; Flockerzi Veit; Nilius Bernd
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Nature 2004;430(7001):748-54.
2004: Nilius Bernd
Store-operated Ca2+ entry channels: still elusive!
Science's STKE : signal transduction knowledge environment 2004;2004(243):pe36.
2004: Lemonnier Loïc; Shuba Yaroslav; Crepin Alexandre; Roudbaraki Morad; Slomianny Christian; Mauroy Brigitte; Nilius Bernd; Prevarskaya Natalia; Skryma Roman
Bcl-2-dependent modulation of swelling-activated Cl- current and ClC-3 expression in human prostate cancer epithelial cells.
Cancer research 2004;64(14):4841-8.
2004: Vriens Joris; Janssens Annelies; Prenen Jean; Nilius Bernd; Wondergem Robert
TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells.
Cell calcium 2004;36(1):19-28.
2004: Lambers Tim T; Weidema A Freek; Nilius Bernd; Hoenderop Joost G J; Bindels René J M
Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.
The Journal of biological chemistry 2004;279(28):28855-61.
2004: Gkika Dimitra; Mahieu Frank; Nilius Bernd; Hoenderop Joost G J; Bindels René J M
80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).
The Journal of biological chemistry 2004;279(25):26351-7.
2004: Best Leonard; Yates Allen P; Decher Neils; Steinmeyer Klaus; Nilius Bernd
Inhibition of glucose-induced electrical activity in rat pancreatic beta-cells by DCPIB, a selective inhibitor of volume-sensitive anion currents.
European journal of pharmacology 2004;489(1-2):13-9.
2004: Nilius Bernd; Prenen Jean; Voets Thomas; Droogmans Guy
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.
Pflügers Archiv : European journal of physiology 2004;448(1):70-5.
2004: Voets Thomas; Janssens Annelies; Droogmans Guy; Nilius Bernd
Outer pore architecture of a Ca2+-selective TRP channel.
The Journal of biological chemistry 2004;279(15):15223-30.
2004: Nilius Bernd; Vriens Joris; Prenen Jean; Droogmans Guy; Voets Thomas
TRPV4 calcium entry channel: a paradigm for gating diversity.
American journal of physiology. Cell physiology 2004;286(2):C195-205.
2004: Nilius Bernd
Is the volume-regulated anion channel VRAC a "water-permeable" channel?
Neurochemical research 2004;29(1):3-8.
2004: Vriens J; Watanabe H; Janssens A; Droogmans G; Voets T; Nilius B
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):396-401.
2004: Srinivas S P; Maertens C; Goon L H; Goon L; Satpathy M; Yue B Y J T; Droogmans G; Nilius B
Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells.
Experimental eye research 2004;78(1):15-26.
2004: Voets Thomas; Nilius Bernd; Hoefs Susan; van der Kemp Annemiete W C M; Droogmans Guy; Bindels Rene J M; Hoenderop Joost G J
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
The Journal of biological chemistry 2004;279(1):19-25.
2004: Seol Geun Hee; Ahn Seung Cheol; Kim Ji Aee; Nilius Bernd; Suh Suk Hyo
Inhibition of endothelium-dependent vasorelaxation by extracellular K(+): a novel controlling signal for vascular contractility.
American journal of physiology. Heart and circulatory physiology 2004;286(1):H329-39.
2004: Nilius Bernd; Voets Thomas
Diversity of TRP channel activation.
Novartis Foundation symposium 2004;258():140-9; discussion 149-59, 263-6.
2003: Nilius Bernd
Pflügers Archiv and the advent of modern electrophysiology. From the first action potential to patch clamp.
Pflügers Archiv : European journal of physiology 2003;447(3):267-71.
2003: Owsianik Grzegorz; Cao Lishuang; Nilius Bernd
Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells.
FEBS letters 2003;554(1-2):173-8.
2003: Nilius Bernd; Prenen Jean; Droogmans Guy; Voets Thomas; Vennekens Rudi; Freichel Marc; Wissenbach Ulrich; Flockerzi Veit
Voltage dependence of the Ca2+-activated cation channel TRPM4.
The Journal of biological chemistry 2003;278(33):30813-20.
2003: Watanabe Hiroyuki; Vriens Joris; Prenen Jean; Droogmans Guy; Voets Thomas; Nilius Bernd
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Nature 2003;424(6947):434-8.
2003: Nijenhuis Tom; Hoenderop Joost G J; Nilius Bernd; Bindels René J M
(Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6.
Pflügers Archiv : European journal of physiology 2003;446(4):401-9.
2003: Talavera Karel; Janssens Annelies; Klugbauer Norbert; Droogmans Guy; Nilius Bernd
Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel alpha1G (CaV3.1).
The Journal of general physiology 2003;121(6):511-28.
2003: Talavera Karel; Janssens Annelies; Klugbauer Norbert; Droogmans Guy; Nilius Bernd
Pore structure influences gating properties of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2003;121(6):529-40.
2003: Nilius Bernd; Watanabe Hiroyuki; Vriens Joris
The TRPV4 channel: structure-function relationship and promiscuous gating behaviour.
Pflügers Archiv : European journal of physiology 2003;446(3):298-303.
2003: Hoenderop Joost G J; Nilius Bernd; Bindels René J M
Epithelial calcium channels: from identification to function and regulation.
Pflügers Archiv : European journal of physiology 2003;446(3):304-8.
2003: den Dekker Els; Hoenderop Joost G J; Nilius Bernd; Bindels René J M
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation.
Cell calcium 2003;33(5-6):497-507.
2003: Watanabe Hiroyuki; Vriens Joris; Janssens Annelies; Wondergem Robert; Droogmans Guy; Nilius Bernd
Modulation of TRPV4 gating by intra- and extracellular Ca2+.
Cell calcium 2003;33(5-6):489-95.
2003: Voets Thomas; Nilius Bernd
The pore of TRP channels: trivial or neglected?
Cell calcium 2003;33(5-6):299-302.
2003: Nilius Bernd
From TRPs to SOCs, CCEs, and CRACs: consensus and controversies.
Cell calcium 2003;33(5-6):293-8.
2003: Cao Lishuang; Owsianik Grzegorz; Jaspers Martine; Janssens Annelies; Cuppens Harry; Cassiman Jean-Jacques; Nilius Bernd
Functional analysis of CFTR chloride channel activity in cells with elevated MDR1 expression.
Biochemical and biophysical research communications 2003;304(2):248-52.
2003: van de Graaf Stan F J; Hoenderop Joost G J; Gkika Dimitra; Lamers Dennis; Prenen Jean; Rescher Ursula; Gerke Volker; Staub Olivier; Nilius Bernd; Bindels René J M
Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.
The EMBO journal 2003;22(7):1478-87.
2003: Voets T; Nilius B
TRPs make sense.
The Journal of membrane biology 2003;192(1):1-8.
2003: Voets Thomas; Janssens Annelies; Prenen Jean; Droogmans Guy; Nilius Bernd
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.
The Journal of general physiology 2003;121(3):245-60.
2003: Nilius Bernd; Weidema Freek; Prenen Jean; Hoenderop Joost G J; Vennekens Rudi; Hoefs Susan; Droogmans Guy; Bindels René J M
The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation.
Pflügers Archiv : European journal of physiology 2003;445(5):584-8.
2003: Hoenderop J G J; Voets T; Hoefs S; Weidema F; Prenen J; Nilius B; Bindels R J M
Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.
The EMBO journal 2003;22(4):776-85.
2003: Nilius B; Droogmans G
Amazing chloride channels: an overview.
Acta physiologica Scandinavica 2003;177(2):119-47.
2003: Nilius Bernd
Calcium-impermeable monovalent cation channels: a TRP connection?
British journal of pharmacology 2003;138(1):5-7.
2003: Nilius Bernd; Droogmans Guy; Wondergem Robert
Transient receptor potential channels in endothelium: solving the calcium entry puzzle?
Endothelium : journal of endothelial cell research 2003;10(1):5-15.
2002: Watanabe Hiroyuki; Vriens Joris; Suh Suk H; Benham Christopher D; Droogmans Guy; Nilius Bernd
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.
The Journal of biological chemistry 2002;277(49):47044-51.
2002: Hoenderop Joost G J; Nilius Bernd; Bindels René J M
ECaC: the gatekeeper of transepithelial Ca2+ transport.
Biochimica et biophysica acta 2002;1600(1-2):6-11.
2002: Müller Dominik; Hoenderop Joost G J; Vennekens Rudi; Eggert Paul; Harangi Ferenc; Méhes Károly; Garcia-Nieto Victor; Claverie-Martin Felix; Os Carel H van; Nilius Bernd; J M Bindels René
Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(9):1614-20.
2002: Voets Thomas; Prenen Jean; Vriens Joris; Watanabe Hiroyuki; Janssens Annelies; Wissenbach Ulrich; Bödding Matthias; Droogmans Guy; Nilius Bernd
Molecular determinants of permeation through the cation channel TRPV4.
The Journal of biological chemistry 2002;277(37):33704-10.
2002: Maertens C; Droogmans G; Verbesselt R; Nilius B
Block of volume-regulated anion channels by selective serotonin reuptake inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):158-65.
2002: Nilius Bernd; Prenen Jean; Hoenderop Joost G J; Vennekens Rudi; Hoefs Susan; Weidema A Freek; Droogmans Guy; Bindels René J M
Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.
The Journal of biological chemistry 2002;277(34):30852-8.
2002: Toth-Zsamboki Emese; Oury Cecile; Watanabe Hiroyuki; Nilius Bernd; Vermylen Jos; Hoylaerts Marc F
The intracellular tyrosine residues of the ATP-gated P2X(1) ion channel are essential for its function.
FEBS letters 2002;524(1-3):15-9.
2002: Carton Iris; Trouet Dominique; Hermans Diane; Barth Holger; Aktories Klaus; Droogmans Guy; Jorgensen Nanna K; Hoffmann Else K; Nilius Bernd; Eggermont Jan
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.
American journal of physiology. Cell physiology 2002;283(1):C115-25.
2002: Suh Suk H; Watanabe Hiroyuki; Droogmans Guy; Nilius Bernd
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 2002;444(3):438-45.
2002: Vennekens R; Voets T; Bindels R J M; Droogmans G; Nilius B
Current understanding of mammalian TRP homologues.
Cell calcium 2002;31(6):253-64.
2002: Watanabe Hiroyuki; Davis John B; Smart Darren; Jerman Jeff C; Smith Graham D; Hayes Phil; Vriens Joris; Cairns William; Wissenbach Ullrich; Prenen Jean; Flockerzi Veit; Droogmans Guy; Benham Christopher D; Nilius Bernd
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
The Journal of biological chemistry 2002;277(16):13569-77.
2002: Lemonnier Loïc; Prevarskaya Natalia; Shuba Yaroslav; Vanden Abeele Fabien; Nilius Bernd; Mazurier Joël; Skryma Roman
Ca2+ modulation of volume-regulated anion channels: evidence for colocalization with store-operated channels.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):222-4.
2002: Raeymaekers Luc; Nilius Bernd; Voets Thomas; Missiaen Ludwig; Van Baelen Kurt; Vanoevelen Jo; Wuytack Frank
Additional fluxes of activator Ca2+ accompanying Ca2+ release from the sarcoplasmic reticulum triggered by insP3-mobilizing agonists.
Novartis Foundation symposium 2002;246():71-6; discussion 76-80, 221-7.
2002: Hoenderop Joost G J; Nilius Bernd; Bindels Rene J M
Molecular mechanism of active Ca2+ reabsorption in the distal nephron.
Annual review of physiology 2002;64():529-49.
2001: Hoenderop J G; Vennekens R; Müller D; Prenen J; Droogmans G; Bindels R J; Nilius B
Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2.
The Journal of physiology 2001;537(Pt 3):747-61.
2001: Decher N; Lang H J; Nilius B; Brüggemann A; Busch A E; Steinmeyer K
DCPIB is a novel selective blocker of I(Cl,swell) and prevents swelling-induced shortening of guinea-pig atrial action potential duration.
British journal of pharmacology 2001;134(7):1467-79.
2001: Voets T; Prenen J; Fleig A; Vennekens R; Watanabe H; Hoenderop J G; Bindels R J; Droogmans G; Penner R; Nilius B
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties.
The Journal of biological chemistry 2001;276(51):47767-70.
2001: Talavera K; Staes M; Janssens A; Klugbauer N; Droogmans G; Hofmann F; Nilius B
Aspartate residues of the Glu-Glu-Asp-Asp (EEDD) pore locus control selectivity and permeation of the T-type Ca(2+) channel alpha(1G).
The Journal of biological chemistry 2001;276(49):45628-35.
2001: Nilius B; Prenen J; Wissenbach U; Bödding M; Droogmans G
Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells.
Pflügers Archiv : European journal of physiology 2001;443(2):227-33.
2001: Nilius B; Prenen J; Vennekens R; Hoenderop J G; Bindels R J; Droogmans G
Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1.
British journal of pharmacology 2001;134(3):453-62.
2001: Nilius B; Droogmans G
Ion channels and their functional role in vascular endothelium.
Physiological reviews 2001;81(4):1415-59.
2001: Vennekens R; Droogmans G; Nilius B
Functional properties of the epithelial Ca2+ channel, ECaC.
General physiology and biophysics 2001;20(3):239-53.
2001: Trouet D; Carton I; Hermans D; Droogmans G; Nilius B; Eggermont J
Inhibition of VRAC by c-Src tyrosine kinase targeted to caveolae is mediated by the Src homology domains.
American journal of physiology. Cell physiology 2001;281(1):C248-56.
2001: Kielbassa-Schnepp K; Strey A; Janning A; Missiaen L; Nilius B; Gerke V
Endothelial intracellular Ca2+ release following monocyte adhesion is required for the transendothelial migration of monocytes.
Cell calcium 2001;30(1):29-40.
2001: Trouet D; Hermans D; Droogmans G; Nilius B; Eggermont J
Inhibition of volume-regulated anion channels by dominant-negative caveolin-1.
Biochemical and biophysical research communications 2001;284(2):461-5.
2001: Nilius B; Prenen J; Vennekens R; Hoenderop J G; Bindels R J; Droogmans G
Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+.
Cell calcium 2001;29(6):417-28.
2001: Wei L; Vankeerberghen A; Cuppens H; Cassiman J J; Droogmans G; Nilius B
The C-terminal part of the R-domain, but not the PDZ binding motif, of CFTR is involved in interaction with Ca(2+)-activated Cl- channels.
Pflügers Archiv : European journal of physiology 2001;442(2):280-5.
2001: Papassotiriou J; Eggermont J; Droogmans G; Nilius B
Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3.
Pflügers Archiv : European journal of physiology 2001;442(2):273-9.
2001: Vennekens R; Prenen J; Hoenderop J G; Bindels R J; Droogmans G; Nilius B
Modulation of the epithelial Ca2+ channel ECaC by extracellular pH.
Pflügers Archiv : European journal of physiology 2001;442(2):237-42.
2001: Nilius B
Chloride channels go cell cycling.
The Journal of physiology 2001;532(Pt 3):581.
2001: Freichel M; Suh S H; Pfeifer A; Schweig U; Trost C; Weissgerber P; Biel M; Philipp S; Freise D; Droogmans G; Hofmann F; Flockerzi V; Nilius B
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.
Nature cell biology 2001;3(2):121-7.
2001: Vennekens R; Prenen J; Hoenderop J G; Bindels R J; Droogmans G; Nilius B
Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells.
The Journal of physiology 2001;530(Pt 2):183-91.
2001: Maertens C; Droogmans G; Chakraborty P; Nilius B
Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine.
British journal of pharmacology 2001;132(1):135-42.
2001: Staes M; Talavera K; Klugbauer N; Prenen J; Lacinova L; Droogmans G; Hofmann F; Nilius B
The amino side of the C-terminus determines fast inactivation of the T-type calcium channel alpha1G.
The Journal of physiology 2001;530(Pt 1):35-45.
2001: Nilius B; Vennekens R; Prenen J; Hoenderop J G; Droogmans G; Bindels R J
The single pore residue Asp542 determines Ca2+ permeation and Mg2+ block of the epithelial Ca2+ channel.
The Journal of biological chemistry 2001;276(2):1020-5.
2001: Eggermont J; Trouet D; Carton I; Nilius B
Cellular function and control of volume-regulated anion channels.
Cell biochemistry and biophysics 2001;35(3):263-74.
2001: Wei L; Freichel M; Jaspers M; Cuppens H; Cassiman J J; Droogmans G; Flockerzi V; Nilius B
Functional interaction between TRP4 and CFTR in mouse aorta endothelial cells.
BMC physiology 2001;1():3.
2000: Shen M R; Droogmans G; Eggermont J; Voets T; Ellory J C; Nilius B
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells.
The Journal of physiology 2000;529 Pt 2():385-94.
2000: Maertens C; Wei L; Droogmans G; Nilius B
Inhibition of volume-regulated and calcium-activated chloride channels by the antimalarial mefloquine.
The Journal of pharmacology and experimental therapeutics 2000;295(1):29-36.
2000: Nilius B; Vennekens R; Prenen J; Hoenderop J G; Bindels R J; Droogmans G
Whole-cell and single channel monovalent cation currents through the novel rabbit epithelial Ca2+ channel ECaC.
The Journal of physiology 2000;527 Pt 2():239-48.
2000: Sabirov R Z; Prenen J; Droogmans G; Nilius B
Extra- and intracellular proton-binding sites of volume-regulated anion channels.
The Journal of membrane biology 2000;177(1):13-22.
2000: Missiaen L; Robberecht W; van den Bosch L; Callewaert G; Parys J B; Wuytack F; Raeymaekers L; Nilius B; Eggermont J; De Smedt H
Abnormal intracellular ca(2+)homeostasis and disease.
Cell calcium 2000;28(1):1-21.
2000: Oury C; Toth-Zsamboki E; Van Geet C; Thys C; Wei L; Nilius B; Vermylen J; Hoylaerts M F
A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue.
The Journal of biological chemistry 2000;275(30):22611-4.
2000: Wagner C A; Huber S M; Wärntges S; Zempel G; Kaba N K; Fux R; Orth N; Busch G L; Waldegger S; Lambert I; Nilius B; Heinle H; Lang F
Effect of urea and osmotic cell shrinkage on Ca2+ entry and contraction of vascular smooth muscle cells.
Pflügers Archiv : European journal of physiology 2000;440(2):295-301.
2000: Wei L; Vankeerberghen A; Jaspers M; Cassiman J; Nilius B; Cuppens H
Suppressive interactions between mutations located in the two nucleotide binding domains of CFTR.
FEBS letters 2000;473(2):149-53.
2000: Papassotiriou J; Köhler R; Prenen J; Krause H; Akbar M; Eggermont J; Paul M; Distler A; Nilius B; Hoyer J
Endothelial K(+) channel lacks the Ca(2+) sensitivity-regulating beta subunit.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):885-94.
2000: Manolopoulos V G; Liekens S; Koolwijk P; Voets T; Peters E; Droogmans G; Lelkes P I; De Clercq E; Nilius B
Inhibition of angiogenesis by blockers of volume-regulated anion channels.
General pharmacology 2000;34(2):107-16.
2000: Maertens C; Wei L; Tytgat J; Droogmans G; Nilius B
Chlorotoxin does not inhibit volume-regulated, calcium-activated and cyclic AMP-activated chloride channels.
British journal of pharmacology 2000;129(4):791-801.
2000: Vennekens R; Hoenderop J G; Prenen J; Stuiver M; Willems P H; Droogmans G; Nilius B; Bindels R J
Permeation and gating properties of the novel epithelial Ca(2+) channel.
The Journal of biological chemistry 2000;275(6):3963-9.
2000: Nilius B; Prenen J; Walsh M P; Carton I; Bollen M; Droogmans G; Eggermont J
Myosin light chain phosphorylation-dependent modulation of volume-regulated anion channels in macrovascular endothelium.
FEBS letters 2000;466(2-3):346-50.
2000: Sabirov R Z; Prenen J; Tomita T; Droogmans G; Nilius B
Reduction of ionic strength activates single volume-regulated anion channels (VRAC) in endothelial cells.
Pflügers Archiv : European journal of physiology 2000;439(3):315-20.
2000: Missiaen L; Callewaert G; Parys J B; Wuytack F; Raeymaekers L; Droogmans G; Nilius B; Eggermont J; De Smedt H
[Intracellular calcium: physiology and physiopathology]
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2000;62(6):471-99.
2000: Nilius B; Eggermont J; Droogmans G
The endothelial volume-regulated anion channel, VRAC.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):313-20.
2000: Suh S H; Droogmans G; Nilius B
Effects of cyanide and deoxyglucose on Ca2+ signalling in macrovascular endothelial cells.
Endothelium : journal of endothelial cell research 2000;7(3):155-68.
1999: Vankeerberghen A; Lin W; Jaspers M; Cuppens H; Nilius B; Cassiman J J
Functional characterization of the CFTR R domain using CFTR/MDR1 hybrid and deletion constructs.
Biochemistry 1999;38(45):14988-98.
1999: Wei L; Vankeerberghen A; Cuppens H; Eggermont J; Cassiman J J; Droogmans G; Nilius B
Interaction between calcium-activated chloride channels and the cystic fibrosis transmembrane conductance regulator.
Pflügers Archiv : European journal of physiology 1999;438(5):635-41.
1999: Suh S H; Vennekens R; Manolopoulos V G; Freichel M; Schweig U; Prenen J; Flockerzi V; Droogmans G; Nilius B
Characterisation of explanted endothelial cells from mouse aorta: electrophysiology and Ca2+ signalling.
Pflügers Archiv : European journal of physiology 1999;438(5):612-20.
1999: Trouet D; Nilius B; Jacobs A; Remacle C; Droogmans G; Eggermont J
Caveolin-1 modulates the activity of the volume-regulated chloride channel.
The Journal of physiology 1999;520 Pt 1():113-9.
1999: Droogmans G; Maertens C; Prenen J; Nilius B
Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells.
British journal of pharmacology 1999;128(1):35-40.
1999: Kamouchi M; Philipp S; Flockerzi V; Wissenbach U; Mamin A; Raeymaekers L; Eggermont J; Droogmans G; Nilius B
Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1999;518 Pt 2():345-58.
1999: Kamouchi M; Droogmans G; Nilius B
Membrane potential as a modulator of the free intracellular Ca2+ concentration in agonist-activated endothelial cells.
General physiology and biophysics 1999;18(2):199-208.
1999: Lang F; Uhlemann A C; Lepple-Wienhues A; Szabo I; Siemen D; Nilius B; Gulbins E
Cell volume regulatory mechanisms in apoptotic cell death.
Herz 1999;24(3):232-5.
1999: Kamouchi M; Mamin A; Droogmans G; Nilius B
Nonselective cation channels in endothelial cells derived from human umbilical vein.
The Journal of membrane biology 1999;169(1):29-38.
1999: Junge S; Brenner B; Lepple-Wienhues A; Nilius B; Lang F; Linderkamp O; Gulbins E
Intracellular mechanisms of L-selectin induced capping.
Cellular signalling 1999;11(4):301-8.
1999: Voets T; Droogmans G; Raskin G; Eggermont J; Nilius B
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5298-303.
1999: Nilius B; Voets T; Prenen J; Barth H; Aktories K; Kaibuchi K; Droogmans G; Eggermont J
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.
The Journal of physiology 1999;516 ( Pt 1)():67-74.
1999: Boegehold M; Lee R M; Mulvany M J; Nilius B; Prewitt R L; Zhang J
Vascular research at INABIS 98.
Journal of vascular research 1999;36(2):147-50.
1999: Vennekens R; Trouet D; Vankeerberghen A; Voets T; Cuppens H; Eggermont J; Cassiman J J; Droogmans G; Nilius B
Inhibition of volume-regulated anion channels by expression of the cystic fibrosis transmembrane conductance regulator.
The Journal of physiology 1999;515 ( Pt 1)():75-85.
1999: Maertens C; Wei L; Voets T; Droogmans G; Nilius B
Block by fluoxetine of volume-regulated anion channels.
British journal of pharmacology 1999;126(2):508-14.
1999: Pedersen S; Pedersen S F; Nilius B; Lambert I H; Hoffmann E K
Mechanical stress induces release of ATP from Ehrlich ascites tumor cells.
Biochimica et biophysica acta 1999;1416(1-2):271-84.
1998: Wei L; Vankeerberghen A; Cuppens H; Droogmans G; Cassiman J J; Nilius B
Phosphorylation site independent single R-domain mutations affect CFTR channel activity.
FEBS letters 1998;439(1-2):121-6.
1998: Vankeerberghen A; Wei L; Teng H; Jaspers M; Cassiman J J; Nilius B; Cuppens H
Characterization of mutations located in exon 18 of the CFTR gene.
FEBS letters 1998;437(1-2):1-4.
1998: Vankeerberghen A; Wei L; Jaspers M; Cassiman J J; Nilius B; Cuppens H
Characterization of 19 disease-associated missense mutations in the regulatory domain of the cystic fibrosis transmembrane conductance regulator.
Human molecular genetics 1998;7(11):1761-9.
1998: Nilius B; Prenen J; Droogmans G
Modulation of volume-regulated anion channels by extra- and intracellular pH.
Pflügers Archiv : European journal of physiology 1998;436(5):742-8.
1998: Droogmans G; Prenen J; Eggermont J; Voets T; Nilius B
Voltage-dependent block of endothelial volume-regulated anion channels by calix[4]arenes.
The American journal of physiology 1998;275(3 Pt 1):C646-52.
1998: Viana F; de Smedt H; Droogmans G; Nilius B
Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium.
Cell calcium 1998;24(2):117-27.
1998: König J; Prenen J; Nilius B; Gerke V
The annexin II-p11 complex is involved in regulated exocytosis in bovine pulmonary artery endothelial cells.
The Journal of biological chemistry 1998;273(31):19679-84.
1998: Fasolato C; Nilius B
Store depletion triggers the calcium release-activated calcium current (ICRAC) in macrovascular endothelial cells: a comparison with Jurkat and embryonic kidney cell lines.
Pflügers Archiv : European journal of physiology 1998;436(1):69-74.
1998: Pedersen S F; Prenen J; Droogmans G; Hoffmann E K; Nilius B
Separate swelling- and Ca2+-activated anion currents in Ehrlich ascites tumor cells.
The Journal of membrane biology 1998;163(2):97-110.
1998: Voets T; Buyse G; Droogmans G; Eggermont J; Nilius B
The GXGXG motif in the pI(Cln) protein is not important for the nucleotide sensitivity of the pI(Cln)-induced Cl- current in Xenopus oocytes.
FEBS letters 1998;426(2):171-3.
1998: Eggermont J; Buyse G; Voets T; Tytgat J; Droogmans G; Nilius B
Is there a link between protein pICln and volume-regulated anion channels?
The Biochemical journal 1998;331 ( Pt 1)():347-9.
1998: Nilius B; Prenen J; Voets T; Eggermont J; Bruzik K S; Shears S B; Droogmans G
Inhibition by inositoltetrakisphosphates of calcium- and volume-activated Cl- currents in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 1998;435(5):637-44.
1998: Buyse G; Trouet D; Voets T; Missiaen L; Droogmans G; Nilius B; Eggermont J
Evidence for the intracellular location of chloride channel (ClC)-type proteins: co-localization of ClC-6a and ClC-6c with the sarco/endoplasmic-reticulum Ca2+ pump SERCA2b.
The Biochemical journal 1998;330 ( Pt 2)():1015-21.
1998: Nilius B; Prenen J; Voets T; Eggermont J; Droogmans G
Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells.
The Journal of physiology 1998;506 ( Pt 2)():353-61.
1998: Voets T; Manolopoulos V; Eggermont J; Ellory C; Droogmans G; Nilius B
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins.
The Journal of physiology 1998;506 ( Pt 2)():341-52.
1998: Cuppens H; Lin W; Jaspers M; Costes B; Teng H; Vankeerberghen A; Jorissen M; Droogmans G; Reynaert I; Goossens M; Nilius B; Cassiman J J
Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation.
The Journal of clinical investigation 1998;101(2):487-96.
1998: Nilius B
Signaltransduction in vascular endothelium: the role of intracellular calcium and ion channels.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1998;60(3):215-50.
1997: Kamouchi M; Trouet D; De Greef C; Droogmans G; Eggermont J; Nilius B
Functional effects of expression of hslo Ca2+ activated K+ channels in cultured macrovascular endothelial cells.
Cell calcium 1997;22(6):497-506.
1997: Kamouchi M; Van Den Bremt K; Eggermont J; Droogmans G; Nilius B
Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;504 ( Pt 3)():545-56.
1997: Viana F; Van den Bosch L; Missiaen L; Vandenberghe W; Droogmans G; Nilius B; Robberecht W
Mibefradil (Ro 40-5967) blocks multiple types of voltage-gated calcium channels in cultured rat spinal motoneurones.
Cell calcium 1997;22(4):299-311.
1997: Voets T; Droogmans G; Nilius B
Modulation of voltage-dependent properties of a swelling-activated Cl- current.
The Journal of general physiology 1997;110(3):313-25.
1997: Trouet D; Nilius B; Voets T; Droogmans G; Eggermont J
Use of a bicistronic GFP-expression vector to characterise ion channels after transfection in mammalian cells.
Pflügers Archiv : European journal of physiology 1997;434(5):632-8.
1997: Manolopoulos V G; Voets T; Declercq P E; Droogmans G; Nilius B
Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells.
The American journal of physiology 1997;273(1 Pt 1):C214-22.
1997: Nilius B; Prenen J; Voets T; Van den Bremt K; Eggermont J; Droogmans G
Kinetic and pharmacological properties of the calcium-activated chloride-current in macrovascular endothelial cells.
Cell calcium 1997;22(1):53-63.
1997: Eggermont J; Buyse G; Voets T; Tytgat J; De Smedt H; Droogmans G; Nilius B
Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.
The Biochemical journal 1997;325 ( Pt 1)():269-76.
1997: Nilius B; Prenen J; Kamouchi M; Viana F; Voets T; Droogmans G
Inhibition by mibefradil, a novel calcium channel antagonist, of Ca(2+)- and volume-activated Cl- channels in macrovascular endothelial cells.
British journal of pharmacology 1997;121(3):547-55.
1997: Nilius B; Szücs G; Heinke S; Voets T; Droogmans G
Multiple types of chloride channels in bovine pulmonary artery endothelial cells.
Journal of vascular research 1997;34(3):220-8.
1997: Haburcák M; Wei L; Viana F; Prenen J; Droogmans G; Nilius B
Calcium-activated potassium channels in cultured human endothelial cells are not directly modulated by nitric oxide.
Cell calcium 1997;21(4):291-300.
1997: Manolopoulos G V; Prenen J; Droogmans G; Nilius B
Thrombin potentiates volume-activated chloride currents in pulmonary artery endothelial cells.
Pflügers Archiv : European journal of physiology 1997;433(6):845-7.
1997: Manolopoulos V G; Droogmans G; Nilius B
Hypotonicity and thrombin activate taurine efflux in BC3H1 and C2C12 myoblasts that is down regulated during differentiation.
Biochemical and biophysical research communications 1997;232(1):74-9.
1997: Szabó I; Nilius B; Zhang X; Busch A E; Gulbins E; Suessbrich H; Lang F
Inhibitory effects of oxidants on n-type K+ channels in T lymphocytes and Xenopus oocytes.
Pflügers Archiv : European journal of physiology 1997;433(5):626-32.
1997: Voets T; Wei L; De Smet P; Van Driessche W; Eggermont J; Droogmans G; Nilius B
Downregulation of volume-activated Cl- currents during muscle differentiation.
The American journal of physiology 1997;272(2 Pt 1):C667-74.
1997: Buyse G; Voets T; Tytgat J; De Greef C; Droogmans G; Nilius B; Eggermont J
Expression of human pICln and ClC-6 in Xenopus oocytes induces an identical endogenous chloride conductance.
The Journal of biological chemistry 1997;272(6):3615-21.
1997: Nilius B; Prenen J; Szücs G; Wei L; Tanzi F; Voets T; Droogmans G
Calcium-activated chloride channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;498 ( Pt 2)():381-96.
1997: Nilius B; Eggermont J; Voets T; Buyse G; Manolopoulos V; Droogmans G
Properties of volume-regulated anion channels in mammalian cells.
Progress in biophysics and molecular biology 1997;68(1):69-119.
1997: Nilius B; Viana F; Droogmans G
Ion channels in vascular endothelium.
Annual review of physiology 1997;59():145-70.
1996: Voets T; Droogmans G; Nilius B
Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1996;497 ( Pt 1)():95-107.
1996: Nilius B; Gerke V; Prenen J; Szücs G; Heinke S; Weber K; Droogmans G
Annexin II modulates volume-activated chloride currents in vascular endothelial cells.
The Journal of biological chemistry 1996;271(48):30631-6.
1996: Nilius B; Eggermont J; Voets T; Droogmans G
Volume-activated Cl- channels.
General pharmacology 1996;27(7):1131-40.
1996: Voets T; Buyse G; Tytgat J; Droogmans G; Eggermont J; Nilius B
The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume-sensitive chloride current.
The Journal of physiology 1996;495 ( Pt 2)():441-7.
1996: Voets T; Droogmans G; Nilius B
Potent block of volume-activated chloride currents in endothelial cells by the uncharged form of quinine and quinidine.
British journal of pharmacology 1996;118(7):1869-71.
1996: Tytgat J; Buyse G; Eggermont J; Droogmans G; Nilius B; Daenens P
Do voltage-gated Kv1.1 and inward rectifier Kir2.1 potassium channels form heteromultimers?
FEBS letters 1996;390(3):280-4.
1996: Missiaen L; De Smedt H; Parys J B; Sienaert I; Vanlingen S; Droogmans G; Nilius B; Casteels R
Hypotonically induced calcium release from intracellular calcium stores.
The Journal of biological chemistry 1996;271(9):4601-4.
1996: Szücs G; Buyse G; Eggermont J; Droogmans G; Nilius B
Characterization of volume-activated chloride currents in endothelial cells from bovine pulmonary artery.
The Journal of membrane biology 1996;149(3):189-97.
1996: Szücs G; Heinke S; De Greef C; Raeymaekers L; Eggermont J; Droogmans G; Nilius B
The volume-activated chloride current in endothelial cells from bovine pulmonary artery is not modulated by phosphorylation.
Pflügers Archiv : European journal of physiology 1996;431(4):540-8.
1996: Szücs G; Heinke S; Droogmans G; Nilius B
Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration.
Pflügers Archiv : European journal of physiology 1996;431(3):467-9.
1996: Buyse G; de Greef C; Raeymaekers L; Droogmans G; Nilius B; Eggermont J
The ubiquitously expressed pICln protein forms homomeric complexes in vitro.
Biochemical and biophysical research communications 1996;218(3):822-7.
1995: Voets T; Szücs G; Droogmans G; Nilius B
Blockers of volume-activated Cl- currents inhibit endothelial cell proliferation.
Pflügers Archiv : European journal of physiology 1995;431(1):132-4.
1995: Nilius B; Sehrer J; De Smet P; Van Driessche W; Droogmans G
Volume regulation in a toad epithelial cell line: role of coactivation of K+ and Cl- channels.
The Journal of physiology 1995;487 ( Pt 2)():367-78.
1995: Heinke S; Szücs G; Norris A; Droogmans G; Nilius B
Inhibition of volume-activated chloride currents in endothelial cells by chromones.
British journal of pharmacology 1995;115(8):1393-8.
1995: Nilius B; Sehrer J; Heinke S; Droogmans G
Ca2+ release and activation of K+ and Cl- currents by extracellular ATP in distal nephron epithelial cells.
The American journal of physiology 1995;269(2 Pt 1):C376-84.
1995: De Greef C; van der Heyden S; Viana F; Eggermont J; De Bruijn E A; Raeymaekers L; Droogmans G; Nilius B
Lack of correlation between mdr-1 expression and volume-activation of cloride-currents in rat colon cancer cells.
Pflügers Archiv : European journal of physiology 1995;430(2):296-8.
1995: De Greef C; Sehrer J; Viana F; van Acker K; Eggermont J; Mertens L; Raeymaekers L; Droogmans G; Nilius B
Volume-activated chloride currents are not correlated with P-glycoprotein expression.
The Biochemical journal 1995;307 ( Pt 3)():713-8.
1995: Viana F; Van Acker K; De Greef C; Eggermont J; Raeymaekers L; Droogmans G; Nilius B
Drug-transport and volume-activated chloride channel functions in human erythroleukemia cells: relation to expression level of P-glycoprotein.
The Journal of membrane biology 1995;145(1):87-98.
1995: Gericke M; Dar O; Droogmans G; Pecht I; Nilius B
Immunological stimulation of single rat basophilic leukemia RBL-2H3 cells co-activates Ca(2+)-entry and K(+)-channels.
Cell calcium 1995;17(1):71-83.
1994: Gericke M; Oike M; Droogmans G; Nilius B
Inhibition of capacitative Ca2+ entry by a Cl- channel blocker in human endothelial cells.
European journal of pharmacology 1994;269(3):381-4.
1994: Oike M; Gericke M; Droogmans G; Nilius B
Calcium entry activated by store depletion in human umbilical vein endothelial cells.
Cell calcium 1994;16(5):367-76.
1994: Oike M; Schwarz G; Sehrer J; Jost M; Gerke V; Weber K; Droogmans G; Nilius B
Cytoskeletal modulation of the response to mechanical stimulation in human vascular endothelial cells.
Pflügers Archiv : European journal of physiology 1994;428(5-6):569-76.
1994: Nilius B; Sehrer J; Viana F; De Greef C; Raeymaekers L; Eggermont J; Droogmans G
Volume-activated Cl- currents in different mammalian non-excitable cell types.
Pflügers Archiv : European journal of physiology 1994;428(3-4):364-71.
1994: De Smet P; Oike M; Droogmans G; Van Driessche W; Nilius B
Responses of endothelial cells to hypotonic solutions: lack of regulatory volume decrease.
Pflügers Archiv : European journal of physiology 1994;428(1):94-6.
1994: Nilius B; Sehrer J; Droogmans G
Permeation properties and modulation of volume-activated Cl(-)-currents in human endothelial cells.
British journal of pharmacology 1994;112(4):1049-56.
1994: Oike M; Droogmans G; Nilius B
Amplitude modulation of Ca2+ signals induced by histamine in human endothelial cells.
Biochimica et biophysica acta 1994;1222(2):287-91.
1994: Oike M; Droogmans G; Nilius B
The volume-activated chloride current in human endothelial cells depends on intracellular ATP.
Pflügers Archiv : European journal of physiology 1994;427(1-2):184-6.
1994: Nilius B; Oike M; Zahradnik I; Droogmans G
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
The Journal of general physiology 1994;103(5):787-805.
1994: Oike M; Droogmans G; Nilius B
Mechanosensitive Ca2+ transients in endothelial cells from human umbilical vein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):2940-4.
1994: Nilius B; Kitamura K; Kuriyama H
Properties of inactivation of calcium channel currents in smooth muscle cells of rabbit portal vein.
Pflügers Archiv : European journal of physiology 1994;426(3-4):239-46.
1994: Schwarz G; Droogmans G; Nilius B
Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells.
Cell calcium 1994;15(1):45-54.
1993: Nilius B; Schwarz G; Droogmans G
Control of intracellular calcium by membrane potential in human melanoma cells.
The American journal of physiology 1993;265(6 Pt 1):C1501-10.
1993: Nilius B; Schwarz G; Droogmans G
Modulation by histamine of an inwardly rectifying potassium channel in human endothelial cells.
The Journal of physiology 1993;472():359-71.
1993: Oike M; Droogmans G; Casteels R; Nilius B
Electrogenic Na+/K(+)-transport in human endothelial cells.
Pflügers Archiv : European journal of physiology 1993;424(3-4):301-7.
1993: Nilius B; Schwartz G; Oike M; Droogmans G
Histamine-activated, non-selective cation currents and Ca2+ transients in endothelial cells from human umbilical vein.
Pflügers Archiv : European journal of physiology 1993;424(3-4):285-93.
1993: Gericke M; Droogmans G; Nilius B
Thimerosal induced changes of intracellular calcium in human endothelial cells.
Cell calcium 1993;14(3):201-7.
1993: Gericke M; Droogmans G; Nilius B
Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells.
Pflügers Archiv : European journal of physiology 1993;422(6):552-7.
1993: Scamps F; Nilius B; Alvarez J; Vassort G
Modulation of L-type Ca channel activity by P2-purinergic agonist in cardiac cells.
Pflügers Archiv : European journal of physiology 1993;422(5):465-71.
1993: Nilius B; Droogmans G; Gericke M; Schwarz G
Nonselective ion pathways in human endothelial cells.
EXS 1993;66():269-80.
1992: Schwarz G; Callewaert G; Droogmans G; Nilius B
Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins.
The Journal of physiology 1992;458():527-38.
1992: Schwarz G; Droogmans G; Nilius B
Shear stress induced membrane currents and calcium transients in human vascular endothelial cells.
Pflügers Archiv : European journal of physiology 1992;421(4):394-6.
1990: Tytgat J; Nilius B; Carmeliet E
Modulation of the T-type cardiac Ca channel by changes in proton concentration.
The Journal of general physiology 1990;96(5):973-90.
1990: Csernoch L; Kovács L; Nilius B; Szücs G
Caffeine and the myoplasmic calcium removal mechanisms in cut frog skeletal muscle fibres.
General physiology and biophysics 1990;9(3):251-66.
1989: Droogmans G; Nilius B
Kinetic properties of the cardiac T-type calcium channel in the guinea-pig.
The Journal of physiology 1989;419():627-50.
1988: Tytgat J; Nilius B; Vereecke J; Carmeliet E
The T-type Ca channel in guinea-pig ventricular myocytes is insensitive to isoproterenol.
Pflügers Archiv : European journal of physiology 1988;411(6):704-6.
1987: Tsien R W; Fox A P; Hess P; McCleskey E W; Nilius B; Nowycky M C; Rosenberg R L
Multiple types of calcium channel in excitable cells.
Society of General Physiologists series 1987;41():167-87.
1986: Reichenbach A; Nilius B; Eberhardt W
Potassium accumulation by the glial membrane pump as revealed by membrane potential recording from isolated rabbit retinal Müller cells.
Neuroscience letters 1986;63(3):280-4.

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