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Bernd Nilius

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All Publications

2013: Bernd Nilius
Introduction (Transient Receptor Potential TRP Channels as Therapeutic Drug Targets: Next Round!).
Current topics in medicinal chemistry 2013;13(3):244-6.
2013: Barbara Colsoul; Bernd Nilius; Rudi Vennekens
Transient Receptor Potential (TRP) Cation Channels in Diabetes.
Current topics in medicinal chemistry 2013;13(3):258-69.
2013: Bernd Nilius; Thomas Voets
The puzzle of TRPV4 channelopathies.
EMBO reports 2013;14(2):152-63.
2012: Thomas Voets; Karel Talavera; Bernd Nilius
Transient receptor potential channel promiscuity frustrates constellation pharmacology.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(49):E3338; author reply E338.
2012: Bernd Nilius; Giovanni Appendino; Grzegorz Owsianik
The transient receptor potential channel TRPA1: from gene to pathophysiology.
Pflügers Archiv : European journal of physiology 2012;464(5):425-58.
2012: Géraldine Rath; Miguel Romero-Perez; Julie Saliez; Joris Vriens; Gaëtane Behets; Caroline Bouzin; Olivier Feron; Elvira Leon-Gomez; Bernd Nilius; Chantal Dessy
Vascular hypoxic preconditioning relies on TRPV4-dependent calcium influx and proper intercellular gap junctions communication.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(9):2241-9.
2012: Serena Materazzi; Silvia Benemei; Christophe Creminon; Camilla Fusi; Pierangelo Geppetti; Bernd Nilius; Riccardo Patacchini; Pamela Pedretti; Jean Prenen; Romina Nassini
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.
Pflügers Archiv : European journal of physiology 2012;463(4):561-9.
2012: Romina Nassini; Bernd Nilius; Frank Porreca; Jean Prenen; Delia Preti; Laura Sadofsky; Orazio Taglialatela-Scafati; Joris Vriens; Eunice Andrè; Giovanni Appendino; Cristina Avonto; Silvia Benemei; Luciano De Petrocellis; Gaetano De Siena; Vincenzo Di Marzo; Greg Dussor; Giancarlo la Marca; Serena Materazzi; Pierangelo Geppetti
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.
Brain : a journal of neurology 2012;135(Pt 2):376-90.
2012: Rudi Vennekens; Aurelie Menigoz; Bernd Nilius
TRPs in the Brain.
Reviews of physiology, biochemistry and pharmacology 2012;163():27-64.
2012: Pieter Uvin; Thomas Voets; Yeranddy A Alpízar; Mathieu Boudes; Wouter Everaerts; Thomas Gevaert; Bernd Nilius; Silvia Pinto; Karel Talavera; Dirk De Ridder
The use of cystometry in small rodents: a study of bladder chemosensation.
Journal of visualized experiments : JoVE 2012;(66):e3869.
2011: Jian Zhong; Giovanni Appendino; Alberto Minassi; Jean Prenen; Orazio Taglialatela-Scafati; Bernd Nilius
Umbellulone modulates TRP channels.
Pflügers Archiv : European journal of physiology 2011;462(6):861-70.
2011: Jian Zhong; Zhiming Zhu; Giovanni Appendino; Federica Pollastro; Jean Prenen; Bernd Nilius
Ligustilide: a novel TRPA1 modulator.
Pflügers Archiv : European journal of physiology 2011;462(6):841-9.
2011: Bernd Nilius; Giovanni Appendino
Tasty and healthy TR(i)Ps. The human quest for culinary pungency.
EMBO reports 2011;12(11):1094-101.
2011: Romina Nassini; Bernd Nilius; Riccardo Patacchini; Pamela Pedretti; Delia Preti; Alberto Cavazzini; Gaetano De Siena; Paola Failli; Maarten Gees; Selena Harrison; Francesca Mancini; Nicola Marchetti; Serena Materazzi; Nadia Moretto; Pierangelo Geppetti
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.
Pain 2011;152(7):1621-31.
2011: Joris Vriens; Grzegorz Owsianik; Thomas Hofmann; Stephan E Philipp; Julia Stab; Xiaodi Chen; Melissa Benoit; Fenqin Xue; Annelies Janssens; Sara Kerselaers; Johannes Oberwinkler; Rudi Vennekens; Thomas Gudermann; Bernd Nilius; Thomas Voets
TRPM3 is a nociceptor channel involved in the detection of noxious heat.
Neuron 2011;70(3):482-94.
2011: Bernd Nilius; Jean Prenen; Grzegorz Owsianik
Irritating channels: the case of TRPA1.
The Journal of physiology 2011;589(Pt 7):1543-9.
2011: Wouter Everaerts; Maarten Gees; Yeranddy Aguiar Alpízar; Ricard Farre; Cindy Leten; Aurelia Apetrei; Ilse Dewachter; Fred Van Leuven; Rudi Vennekens; Dirk De Ridder; Bernd Nilius; Thomas Voets; Karel Talavera
The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil.
Current biology : CB 2011;21(4):316-21.
2011: Roberta Zaninetti; Alessandra Fornarelli; Monica Ciarletta; Dmitry Lim; Antonio Caldarelli; Tracey Pirali; Anna Cariboni; Grzegorz Owsianik; Bernd Nilius; Pier Luigi Canonico; Carla Distasi; Armando Genazzani
Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells.
Journal of neurochemistry 2011;116(4):606-15.
2011: Barbara Colsoul; Rudi Vennekens; Bernd Nilius
Transient receptor potential cation channels in pancreatic β cells.
Reviews of physiology, biochemistry and pharmacology 2011;161():87-110.
2011: Bernd Nilius; Grzegorz Owsianik
The transient receptor potential family of ion channels.
Genome biology 2011;12(3):218.
2010: Bernd Nilius
Pressing and squeezing with Piezos.
EMBO reports 2010;11(12):902-3.
2010: Wouter Everaerts; Xiaoguang Zhen; Debapriya Ghosh; Joris Vriens; Thomas Gevaert; James P Gilbert; Neil J Hayward; Colleen R McNamara; Fenqin Xue; Magdalene M Moran; Timothy Strassmaier; Eda Uykal; Grzegorz Owsianik; Rudi Vennekens; Dirk De Ridder; Bernd Nilius; Christopher M Fanger; Thomas Voets
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):19084-9.
2010: Maarten Gees; Barbara Colsoul; Bernd Nilius
The role of transient receptor potential cation channels in Ca2+ signaling.
Cold Spring Harbor perspectives in biology 2010;2(10):a003962.
2010: Wouter Everaerts; Bernd Nilius; Grzegorz Owsianik
The vanilloid transient receptor potential channel TRPV4: from structure to disease.
Progress in biophysics and molecular biology 2010;103(1):2-17.
2010: Bernd Nilius
A Special Issue on channelopathies.
Pflügers Archiv : European journal of physiology 2010;460(2):221-2.
2010: Bernd Nilius; Grzegorz Owsianik
Transient receptor potential channelopathies.
Pflügers Archiv : European journal of physiology 2010;460(2):437-50.
2010: Thomas Gevaert; Grzegorz Owsianik; Graham Hutchings; Wouter Everaerts; Bernd Nilius; Dirk De Ridder
Maturation of stretch-induced contractile activity and its muscarinic regulation in isolated whole bladder strips from rat.
Neurourology and urodynamics 2010;29(5):789-96.
2010: Barbara Colsoul; Anica Schraenen; Katleen Lemaire; Roel Quintens; Leentje Van Lommel; Andrei Segal; Grzegorz Owsianik; Karel Talavera; Thomas Voets; Robert Margolskee; Zaza Kokrashvili; Patrick Gilon; Bernd Nilius; Frans Schuit; Rudi Vennekens
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):5208-13.
2010: Yuji Karashima; Jean Prenen; Karel Talavera; Annelies Janssens; Thomas Voets; Bernd Nilius
Agonist-induced changes in Ca(2+) permeation through the nociceptor cation channel TRPA1.
Biophysical journal 2010;98(5):773-83.
2010: Wouter Everaerts; Joris Vriens; Grzegorz Owsianik; Giovanni Appendino; Thomas Voets; Dirk De Ridder; Bernd Nilius
Functional characterization of transient receptor potential channels in mouse urothelial cells.
American journal of physiology. Renal physiology 2010;298(3):F692-701.
2010: Frank Mahieu; Annelies Janssens; Maarten Gees; Karel Talavera; Bernd Nilius; Thomas Voets
Modulation of the cold-activated cation channel TRPM8 by surface charge screening.
The Journal of physiology 2010;588(Pt 2):315-24.
2009: Bernd Nilius
Polycystins under pressure.
Cell 2009;139(3):466-7.
2009: Karel Talavera; Maarten Gees; Yuji Karashima; Victor Meseguer; Jeroen A J Vanoirbeek; Nils Damann; Wouter Everaerts; Melissa Benoit; Annelies Janssens; Rudi Vennekens; Felix Viana; Benoit Nemery; Bernd Nilius; Thomas Voets
Nicotine activates the chemosensory cation channel TRPA1.
Nature neuroscience 2009;12(10):1293-9.
2009: Barbara Colsoul; Bernd Nilius; Rudi Vennekens
On the putative role of transient receptor potential cation channels in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(10):1456-66.
2009: Thomas Gevaert; Grzegorz Owsianik; Graham Hutchings; Liesbeth Van Leuven; Wouter Everaerts; Bernd Nilius; Dirk De Ridder
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity.
European urology 2009;56(1):168-76.
2009: Joris Vriens; Giovanni Appendino; Bernd Nilius
Pharmacology of vanilloid transient receptor potential cation channels.
Molecular pharmacology 2009;75(6):1262-79.
2009: Thomas Kjaer Klausen; Alberto Pagani; Alberto Minassi; Abdellah Ech-Chahad; Jean Prenen; Grzegorz Owsianik; Else Kay Hoffmann; Stine Falsig Pedersen; Giovanni Appendino; Bernd Nilius
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study.
Journal of medicinal chemistry 2009;52(9):2933-9.
2009: Graham Hutchings; Thomas Gevaert; Jan Deprest; Bernd Nilius; Olivia Williams; Dirk De Ridder
The effect of extracellular adenosine triphosphate on the spontaneous contractility of human myometrial strips.
European journal of obstetrics, gynecology, and reproductive biology 2009;143(2):79-83.
2009: Wouter Everaerts; M Rosario Sepúlveda; Thomas Gevaert; Tania Roskams; Bernd Nilius; Dirk De Ridder
Where is TRPV1 expressed in the bladder, do we see the real channel?
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(4):421-5.
2009: Takahiro Shimizu; Grzegorz Owsianik; Marc Freichel; Veit Flockerzi; Bernd Nilius; Rudi Vennekens
TRPM4 regulates migration of mast cells in mice.
Cell calcium 2009;45(3):226-32.
2009: Takahiro Shimizu; Annelies Janssens; Thomas Voets; Bernd Nilius
Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume.
Pflügers Archiv : European journal of physiology 2009;457(4):795-807.
2009: Yuji Karashima; Karel Talavera; Wouter Everaerts; Annelies Janssens; Kelvin Y Kwan; Rudi Vennekens; Bernd Nilius; Thomas Voets
TRPA1 acts as a cold sensor in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1273-8.
2009: Thomas Voets; Bernd Nilius
TRPCs, GPCRs and the Bayliss effect.
The EMBO journal 2009;28(1):4-5.
2009: N Damann; Grzegorz Owsianik; S Li; C Poll; Bernd Nilius
The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils.
Acta physiologica (Oxford, England) 2009;195(1):3-11.
2008: Bernd Nilius; Thomas Voets
A TRP channel-steroid marriage.
Nature cell biology 2008;10(12):1383-4.
2008: Annemarieke E Loot; Rüdiger Popp; Beate Fisslthaler; Joris Vriens; Bernd Nilius; Ingrid Fleming
Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation.
Cardiovascular research 2008;80(3):445-52.
2008: Bernd Nilius; Grzegorz Owsianik; Thomas Voets
Transient receptor potential channels meet phosphoinositides.
The EMBO journal 2008;27(21):2809-16.
2008: Anke Fabian; T Fortmann; Peter Dieterich; Christoph Riethmüller; P Schön; Sabine Mally; Bernd Nilius; Albrecht Schwab
TRPC1 channels regulate directionality of migrating cells.
Pflügers Archiv : European journal of physiology 2008;457(2):475-84.
2008: Yuji Karashima; Jean Prenen; Victor Meseguer; Grzegorz Owsianik; Thomas Voets; Bernd Nilius
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators.
Pflügers Archiv : European journal of physiology 2008;457(1):77-89.
2008: Nils Damann; Thomas Voets; Bernd Nilius
TRPs in our senses.
Current biology : CB 2008;18(18):R880-9.
2008: Ritsuko Masuyama; Joris Vriens; Thomas Voets; Yuji Karashima; Grzegorz Owsianik; Rudi Vennekens; Liesbet Lieben; Sophie Torrekens; Karen Moermans; An Vanden Bosch; Roger Bouillon; Bernd Nilius; Geert Carmeliet
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts.
Cell metabolism 2008;8(3):257-65.
2008: Michael Köttgen; Björn Buchholz; Miguel A Garcia-Gonzalez; Fruzsina Kotsis; Xiao Fu; Mara Doerken; Christopher Boehlke; Daniel Steffl; Robert Tauber; Tomasz Wegierski; Roland Nitschke; Makoto Suzuki; Albrecht Kramer-Zucker; Gregory G Germino; Terry Watnick; Jean Prenen; Bernd Nilius; E Wolfgang Kuehn; Gerd Walz
TRPP2 and TRPV4 form a polymodal sensory channel complex.
The Journal of cell biology 2008;182(3):437-47.
2008: Matthew J Rock; Jean Prenen; Vincent A Funari; Tara L Funari; Barry Merriman; Stanley F Nelson; Ralph S Lachman; William R Wilcox; Soraya Reyno; Roberto Quadrelli; Alicia Vaglio; Grzegorz Owsianik; Annelies Janssens; Thomas Voets; Shiro Ikegawa; Toshiro Nagai; David L Rimoin; Bernd Nilius; Daniel H Cohn
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia.
Nature genetics 2008;40(8):999-1003.
2008: R Wondergem; Tom Ecay; Frank Mahieu; Grzegorz Owsianik; Bernd Nilius
HGF/SF and menthol increase human glioblastoma cell calcium and migration.
Biochemical and biophysical research communications 2008;372(1):210-5.
2008: Karel Talavera; Bernd Nilius; Thomas Voets
Neuronal TRP channels: thermometers, pathfinders and life-savers.
Trends in neurosciences 2008;31(6):287-95.
2008: Reza Sharif Naeini; Alexandra Dedman; Joost H A Folgering; Fabrice DUPRAT; Amanda Patel; Bernd Nilius; Eric Honoré
TRP channels and mechanosensory transduction: insights into the arterial myogenic response.
Pflügers Archiv : European journal of physiology 2008;456(3):529-40.
2008: Karel Talavera; Keiko Yasumatsu; Ryusuke Yoshida; Robert Margolskee; Thomas Voets; Yuzo Ninomiya; Bernd Nilius
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1343-55.
2008: I Dewachter; L Ris; S Croes; P Borghgraef; H Devijver; T Voets; Bernd Nilius; E Godaux; Fred Van Leuven
Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
Neurobiology of aging 2008;29(5):639-52.
2008: Dieter D'hoedt; Grzegorz Owsianik; Jean Prenen; Math Pham Cuajungco; Christian Grimm; Stefan Heller; Thomas Voets; Bernd Nilius
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3.
The Journal of biological chemistry 2008;283(10):6272-80.
2008: Joris Vriens; Bernd Nilius; Rudi Vennekens
Herbal compounds and toxins modulating TRP channels.
Current neuropharmacology 2008;6(1):79-96.
2008: Jenny A Wilkinson; Jason L Scragg; John P Boyle; Bernd Nilius; Chris Peers
H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death.
Pflügers Archiv : European journal of physiology 2008;455(6):1141-51.
2008: J Saliez; Caroline Bouzin; G Rath; Philippe Ghisdal; Fanny Desjardins; R Rezzani; Luigi Rodella; J Vriens; Bernd Nilius; Olivier Feron; Jean-Luc Balligand; Chantal Dessy
Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.
Circulation 2008;117(8):1065-74.
2008: Victor Meseguer; Yuji Karashima; Karel Talavera; Dieter D'Hoedt; Tansy Donovan-Rodriguez; Felix Viana; Bernd Nilius; Thomas Voets
Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(3):576-86.
2008: Graham Hutchings; Thomas Gevaert; Jan Deprest; Tania Roskams; Alfons Van Lommel; Bernd Nilius; Dirk De Ridder
Immunohistochemistry using an antibody to unphosphorylated connexin 43 to identify human myometrial interstitial cells.
Reproductive biology and endocrinology : RB&E 2008;6():43.
2008: David A Hughes; Kun Tang; Rainer Strotmann; Torsten Schöneberg; Jean Prenen; Bernd Nilius; Mark Stoneking
Parallel selection on TRPV6 in human populations.
PloS one 2008;3(2):e1686.
2008: Rudi Vennekens; Grzegorz Owsianik; Bernd Nilius
Vanilloid transient receptor potential cation channels: an overview.
Current pharmaceutical design 2008;14(1):18-31.
2008: G Hutchings; Thomas Gevaert; Jan Deprest; Bernd Nilius; Dirk De Ridder
Effect of prolonged c-kit receptor inhibition by imatinib mesylate on the uterine contractility of pregnant rabbits.
Gynecologic and obstetric investigation 2008;65(2):108-11.
2008: Wouter Everaerts; Thomas Gevaert; Bernd Nilius; Dirk De Ridder
On the origin of bladder sensing: Tr(i)ps in urology.
Neurourology and urodynamics 2008;27(4):264-73.
2007: Thomas Gevaert; Joris Vriens; Andrei Segal; Wouter Everaerts; Tania Roskams; Karel Talavera; Grzegorz Owsianik; Wolfgang Liedtke; Dirk Daelemans; Ilse Dewachter; Fred Van Leuven; Thomas Voets; Dirk De Ridder; Bernd Nilius
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
The Journal of clinical investigation 2007;117(11):3453-62.
2007: Diomedes E Logothetis; Bernd Nilius
Dynamic changes in phosphoinositide levels control ion channel activity.
Pflügers Archiv : European journal of physiology 2007;455(1):1-3.
2007: Tibor Rohacs; Bernd Nilius
Regulation of transient receptor potential (TRP) channels by phosphoinositides.
Pflügers Archiv : European journal of physiology 2007;455(1):157-68.
2007: Yuji Karashima; Nils Damann; Jean Prenen; Karel Talavera; Andrei Segal; Thomas Voets; Bernd Nilius
Bimodal action of menthol on the transient receptor potential channel TRPA1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(37):9874-84.
2007: Thomas Voets; Bernd Nilius
Modulation of TRPs by PIPs.
The Journal of physiology 2007;582(Pt 3):939-44.
2007: Bernd Nilius
TRP channels in disease.
Biochimica et biophysica acta 2007;1772(8):805-12.
2007: Bernd Nilius; Thomas Voets
Neurophysiology: channelling cold reception.
Nature 2007;448(7150):147-8.
2007: J Waning; Joris Vriens; Grzegorz Owsianik; L Stüwe; Sabine Mally; Anke Fabian; C Frippiat; Bernd Nilius; Albrecht Schwab
A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migration.
Cell calcium 2007;42(1):17-25.
2007: Catalin N Topala; Wouter Tiel Groenestege; Stéphanie Thébault; Dennis van den Berg; Bernd Nilius; Joost G J Hoenderop; René J M Bindels
Molecular determinants of permeation through the cation channel TRPM6.
Cell calcium 2007;41(6):513-23.
2007: Joris Vriens; Grzegorz Owsianik; Annelies Janssens; Thomas Voets; Bernd Nilius
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4.
The Journal of biological chemistry 2007;282(17):12796-803.
2007: Thomas Voets; Grzegorz Owsianik; Annelies Janssens; Karel Talavera; Bernd Nilius
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli.
Nature chemical biology 2007;3(3):174-82.
2007: Rudi Vennekens; Jenny Olausson; Marcel Meissner; Wilhelm Bloch; Ilka Mathar; Stephan E Philipp; Frank Schmitz; Petra Weissgerber; Bernd Nilius; Veit Flockerzi; Marc Freichel
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4.
Nature immunology 2007;8(3):312-20.
2007: Frank Mahieu; Grzegorz Owsianik; Leen Verbert; Annelies Janssens; Humbert De Smedt; Bernd Nilius; Thomas Voets
TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
The Journal of biological chemistry 2007;282(5):3325-36.
2007: Bernd Nilius; Frank Mahieu; Y Karashima; Thomas Voets
Regulation of TRP channels: a voltage-lipid connection.
Biochemical Society transactions 2007;35(Pt 1):105-8.
2007: Karel Talavera; Yuzo Ninomiya; C Winkel; Thomas Voets; Bernd Nilius
Influence of temperature on taste perception.
Cellular and molecular life sciences : CMLS 2007;64(4):377-81.
2007: Bernd Nilius
Transient receptor potential (TRP) cation channels: rewarding unique proteins.
Bulletin et mémoires de l'Académie royale de médecine de Belgique 2007;162(3-4):244-53.
2007: Stine F Pedersen; Bernd Nilius
Transient receptor potential channels in mechanosensing and cell volume regulation.
Methods in enzymology 2007;428():183-207.
2007: Thomas Gevaert; Joachim Vandepitte; Graham Hutchings; Joris Vriens; Bernd Nilius; Dirk De Ridder
TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.
Neurourology and urodynamics 2007;26(3):440-50; discussion 451-3.
2007: Bernd Nilius; Grzegorz Owsianik; Thomas Voets; John A Peters
Transient receptor potential cation channels in disease.
Physiological reviews 2007;87(1):165-217.
2007: Thomas Voets; Grzegorz Owsianik; Bernd Nilius
TRPM8.
Handbook of experimental pharmacology 2007;(179):329-44.
2007: Rudi Vennekens; Bernd Nilius
Insights into TRPM4 function, regulation and physiological role.
Handbook of experimental pharmacology 2007;(179):269-85.
2007: Thomas Gevaert; Joachim Vandepitte; Dieter Ost; Bernd Nilius; Dirk De Ridder
Autonomous contractile activity in the isolated rat bladder is modulated by a TRPV1 dependent mechanism.
Neurourology and urodynamics 2007;26(3):424-32; discussion 451-3.
2006: Bernd Nilius; Rudi Vennekens
From cardiac cation channels to the molecular dissection of the transient receptor potential channel TRPM4.
Pflügers Archiv : European journal of physiology 2006;453(3):313-21.
2006: Karel Talavera; Bernd Nilius
Evidence for common structural determinants of activation and inactivation in T-type Ca2+ channels.
Pflügers Archiv : European journal of physiology 2006;453(2):189-201.
2006: Bernd Nilius; Karel Talavera; Alexei Verkhratsky
T-type calcium channels: the never ending story.
Cell calcium 2006;40(2):81-8.
2006: Karel Talavera; Bernd Nilius
Biophysics and structure-function relationship of T-type Ca2+ channels.
Cell calcium 2006;40(2):97-114.
2006: Tim T Lambers; Frank Mahieu; Elena Oancea; Louis J C Hoofd; Frank de Lange; Arjen Mensenkamp; Thomas Voets; Bernd Nilius; David E Clapham; Joost G J Hoenderop; René J M Bindels
Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.
The EMBO journal 2006;25(13):2978-88.
2006: Math P Cuajungco; Christian Grimm; Kazuo Oshima; Dieter D'hoedt; Bernd Nilius; Arjen Mensenkamp; René J M Bindels; Markus Plomann; Stefan Heller
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.
The Journal of biological chemistry 2006;281(27):18753-62.
2006: Bernd Nilius; Frank Mahieu
A road map for TR(I)Ps.
Molecular cell 2006;22(3):297-307.
2006: Nina Ullrich; Adrian Caplanusi; Bert Brône; Diane Hermans; Els Larivière; Bernd Nilius; Willy Van Driessche; Jan Eggermont
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells.
American journal of physiology. Cell physiology 2006;290(5):C1287-96.
2006: Bernd Nilius; Frank Mahieu; Jean Prenen; Annelies Janssens; Grzegorz Owsianik; Rudi Vennekens; Thomas Voets
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.
The EMBO journal 2006;25(3):467-78.
2006: Grzegorz Owsianik; D D'hoedt; Thomas Voets; Bernd Nilius
Structure-function relationship of the TRP channel superfamily.
Reviews of physiology, biochemistry and pharmacology 2006;156():61-90.
2006: G Hutchings; Jan Deprest; Bernd Nilius; Tania Roskams; Dirk De Ridder
The effect of imatinib mesylate on the contractility of isolated rabbit myometrial strips.
Gynecologic and obstetric investigation 2006;62(2):79-83.
2006: Grzegorz Owsianik; Karel Talavera; Thomas Voets; Bernd Nilius
Permeation and selectivity of TRP channels.
Annual review of physiology 2006;68():685-717.
2005: Karel Talavera; Keiko Yasumatsu; Thomas Voets; Guy Droogmans; Noriatsu Shigemura; Yuzo Ninomiya; Robert Margolskee; Bernd Nilius
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.
Nature 2005;438(7070):1022-5.
2005: Joris Vriens; Grzegorz Owsianik; Beate Fisslthaler; M Suzuki; Annelies Janssens; Thomas Voets; Christophe Morisseau; Bruce D Hammock; Ingrid Fleming; Rudi Busse; Bernd Nilius
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium.
Circulation research 2005;97(9):908-15.
2005: Bernd Nilius; Thomas Voets
TRP channels: a TR(I)P through a world of multifunctional cation channels.
Pflügers Archiv : European journal of physiology 2005;451(1):1-10.
2005: Stine F Pedersen; Grzegorz Owsianik; Bernd Nilius
TRP channels: an overview.
Cell calcium 2005;38(3-4):233-52.
2005: Bernd Nilius; Karel Talavera; Grzegorz Owsianik; Jean Prenen; Guy Droogmans; Thomas Voets
Gating of TRP channels: a voltage connection?
The Journal of physiology 2005;567(Pt 1):35-44.
2005: Bernd Nilius; Thomas Voets; John Peters
TRP channels in disease.
Science's STKE : signal transduction knowledge environment 2005;2005(295):re8.
2005: Thomas Voets; Karel Talavera; Grzegorz Owsianik; Bernd Nilius
Sensing with TRP channels.
Nature chemical biology 2005;1(2):85-92.
2005: Annick Vastiau; Lishuang Cao; Martine Jaspers; Grzegorz Owsianik; Veerle Janssens; Harry Cuppens; Jozef Goris; Bernd Nilius; Jean-Jacques Cassiman
Interaction of the protein phosphatase 2A with the regulatory domain of the cystic fibrosis transmembrane conductance regulator channel.
FEBS letters 2005;579(16):3392-6.
2005: Bernd Nilius; Jean Prenen; Annelies Janssens; Grzegorz Owsianik; Chunbo Wang; Michael X Zhu; Thomas Voets
The selectivity filter of the cation channel TRPM4.
The Journal of biological chemistry 2005;280(24):22899-906.
2005: Lishuang Cao; Grzegorz Owsianik; Frédéric Becq; Bernd Nilius
Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells.
Biochemical and biophysical research communications 2005;331(2):503-11.
2005: Nina D Ullrich; Thomas Voets; Jean Prenen; Rudi Vennekens; Karel Talavera; Guy Droogmans; Bernd Nilius
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.
Cell calcium 2005;37(3):267-78.
2005: Bernd Nilius; Jean Prenen; Jisen Tang; Chunbo Wang; Grzegorz Owsianik; Annelies Janssens; Thomas Voets; Michael X Zhu
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.
The Journal of biological chemistry 2005;280(8):6423-33.
2005: Joost G J Hoenderop; Bernd Nilius; René J M Bindels
Calcium absorption across epithelia.
Physiological reviews 2005;85(1):373-422.
2004: Joris Vriens; Grzegorz Owsianik; Thomas Voets; Guy Droogmans; Bernd Nilius
Invertebrate TRP proteins as functional models for mammalian channels.
Pflügers Archiv : European journal of physiology 2004;449(3):213-26.
2004: Bernd Nilius; Jean Prenen; Annelies Janssens; Thomas Voets; Guy Droogmans
Decavanadate modulates gating of TRPM4 cation channels.
The Journal of physiology 2004;560(Pt 3):753-65.
2004: Karel Talavera; Mik Staes; Annelies Janssens; Guy Droogmans; Bernd Nilius
Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2004;124(3):225-38.
2004: Thomas Voets; Guy Droogmans; Ulrich Wissenbach; Annelies Janssens; Veit Flockerzi; Bernd Nilius
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Nature 2004;430(7001):748-54.
2004: Bernd Nilius
Store-operated Ca2+ entry channels: still elusive!
Science's STKE : signal transduction knowledge environment 2004;2004(243):pe36.
2004: Loïc Lemonnier; Yaroslav Shuba; Alexandre Crepin; Morad Roudbaraki; Christian Slomianny; Brigitte Mauroy; Bernd Nilius; Natalia Prevarskaya; Roman Skryma
Bcl-2-dependent modulation of swelling-activated Cl- current and ClC-3 expression in human prostate cancer epithelial cells.
Cancer research 2004;64(14):4841-8.
2004: Tim T Lambers; A Freek Weidema; Bernd Nilius; Joost G J Hoenderop; René J M Bindels
Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.
The Journal of biological chemistry 2004;279(28):28855-61.
2004: Joris Vriens; Annelies Janssens; Jean Prenen; Bernd Nilius; Robert Wondergem
TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells.
Cell calcium 2004;36(1):19-28.
2004: Dimitra Gkika; Frank Mahieu; Bernd Nilius; Joost G J Hoenderop; René J M Bindels
80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).
The Journal of biological chemistry 2004;279(25):26351-7.
2004: Thomas Voets; Annelies Janssens; Guy Droogmans; Bernd Nilius
Outer pore architecture of a Ca2+-selective TRP channel.
The Journal of biological chemistry 2004;279(15):15223-30.
2004: Leonard Best; Allen P Yates; Niels Decher; Klaus Steinmeyer; Bernd Nilius
Inhibition of glucose-induced electrical activity in rat pancreatic beta-cells by DCPIB, a selective inhibitor of volume-sensitive anion currents.
European journal of pharmacology 2004;489(1-2):13-9.
2004: Bernd Nilius; Jean Prenen; Thomas Voets; Guy Droogmans
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.
Pflügers Archiv : European journal of physiology 2004;448(1):70-5.
2004: Bernd Nilius; Joris Vriens; Jean Prenen; Guy Droogmans; Thomas Voets
TRPV4 calcium entry channel: a paradigm for gating diversity.
American journal of physiology. Cell physiology 2004;286(2):C195-205.
2004: Joris Vriens; Hiroyuki Watanabe; Annelies Janssens; Guy Droogmans; Thomas Voets; Bernd Nilius
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):396-401.
2004: Thomas Voets; Bernd Nilius; Susan Hoefs; Annemiete W C M van der Kemp; Guy Droogmans; René J M Bindels; Joost G J Hoenderop
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
The Journal of biological chemistry 2004;279(1):19-25.
2004: Bernd Nilius; Thomas Voets
Diversity of TRP channel activation.
Novartis Foundation symposium 2004;258():140-9; discussion 149-59, 263-6.
2004: Bernd Nilius
Is the volume-regulated anion channel VRAC a "water-permeable" channel?
Neurochemical research 2004;29(1):3-8.
2004: Sangly P Srinivas; Chantal Maertens; L H Goon; Levina Goon; Minati Satpathy; Beatrice Y J T Yue; G Droogmans; Bernd Nilius
Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells.
Experimental eye research 2004;78(1):15-26.
2004: Geun Hee Seol; Seung Cheol Ahn; Ji Aee Kim; Bernd Nilius; Suk Hyo Suh
Inhibition of endothelium-dependent vasorelaxation by extracellular K(+): a novel controlling signal for vascular contractility.
American journal of physiology. Heart and circulatory physiology 2004;286(1):H329-39.
2003: Bernd Nilius
Pflügers Archiv and the advent of modern electrophysiology. From the first action potential to patch clamp.
Pflügers Archiv : European journal of physiology 2003;447(3):267-71.
2003: Grzegorz Owsianik; Lishuang Cao; Bernd Nilius
Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells.
FEBS letters 2003;554(1-2):173-8.
2003: Bernd Nilius; Jean Prenen; Guy Droogmans; Thomas Voets; Rudi Vennekens; Marc Freichel; Ulrich Wissenbach; Veit Flockerzi
Voltage dependence of the Ca2+-activated cation channel TRPM4.
The Journal of biological chemistry 2003;278(33):30813-20.
2003: Hiroyuki Watanabe; Joris Vriens; Jean Prenen; Guy Droogmans; Thomas Voets; Bernd Nilius
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Nature 2003;424(6947):434-8.
2003: Tom Nijenhuis; Joost G J Hoenderop; Bernd Nilius; René J M Bindels
(Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6.
Pflügers Archiv : European journal of physiology 2003;446(4):401-9.
2003: Karel Talavera; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Bernd Nilius
Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel alpha1G (CaV3.1).
The Journal of general physiology 2003;121(6):511-28.
2003: Karel Talavera; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Bernd Nilius
Pore structure influences gating properties of the T-type Ca2+ channel alpha1G.
The Journal of general physiology 2003;121(6):529-40.
2003: Bernd Nilius; Hiroyuki Watanabe; Joris Vriens
The TRPV4 channel: structure-function relationship and promiscuous gating behaviour.
Pflügers Archiv : European journal of physiology 2003;446(3):298-303.
2003: Joost G J Hoenderop; Bernd Nilius; René J M Bindels
Epithelial calcium channels: from identification to function and regulation.
Pflügers Archiv : European journal of physiology 2003;446(3):304-8.
2003: Lishuang Cao; Grzegorz Owsianik; Martine Jaspers; Annelies Janssens; Harry Cuppens; Jean-Jacques Cassiman; Bernd Nilius
Functional analysis of CFTR chloride channel activity in cells with elevated MDR1 expression.
Biochemical and biophysical research communications 2003;304(2):248-52.
2003: Els den Dekker; Joost G J Hoenderop; Bernd Nilius; René J M Bindels
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation.
Cell calcium 2003;33(5-6):497-507.
2003: Hiroyuki Watanabe; Joris Vriens; Annelies Janssens; Robert Wondergem; Guy Droogmans; Bernd Nilius
Modulation of TRPV4 gating by intra- and extracellular Ca2+.
Cell calcium 2003;33(5-6):489-95.
2003: Thomas Voets; Bernd Nilius
The pore of TRP channels: trivial or neglected?
Cell calcium 2003;33(5-6):299-302.
2003: Bernd Nilius
From TRPs to SOCs, CCEs, and CRACs: consensus and controversies.
Cell calcium 2003;33(5-6):293-8.
2003: Stan F J van de Graaf; Joost G J Hoenderop; Dimitra Gkika; Dennis Lamers; Jean Prenen; Ursula Rescher; Volker Gerke; Olivier Staub; Bernd Nilius; René J M Bindels
Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.
The EMBO journal 2003;22(7):1478-87.
2003: Thomas Voets; Bernd Nilius
TRPs make sense.
The Journal of membrane biology 2003;192(1):1-8.
2003: Thomas Voets; Annelies Janssens; Jean Prenen; Guy Droogmans; Bernd Nilius
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.
The Journal of general physiology 2003;121(3):245-60.
2003: Joost G J Hoenderop; Thomas Voets; Susan Hoefs; Freek A Weidema; Jean Prenen; Bernd Nilius; René J M Bindels
Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.
The EMBO journal 2003;22(4):776-85.
2003: Bernd Nilius; Freek A Weidema; Jean Prenen; Joost G J Hoenderop; Rudi Vennekens; Susan Hoefs; Guy Droogmans; René J M Bindels
The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation.
Pflügers Archiv : European journal of physiology 2003;445(5):584-8.
2003: Bernd Nilius; G Droogmans
Amazing chloride channels: an overview.
Acta physiologica Scandinavica 2003;177(2):119-47.
2003: Bernd Nilius; Guy Droogmans; Robert Wondergem
Transient receptor potential channels in endothelium: solving the calcium entry puzzle?
Endothelium : journal of endothelial cell research 2003;10(1):5-15.
2003: Bernd Nilius
Calcium-impermeable monovalent cation channels: a TRP connection?
British journal of pharmacology 2003;138(1):5-7.
2002: Hiroyuki Watanabe; Joris Vriens; Suk H Suh; Christopher D Benham; Guy Droogmans; Bernd Nilius
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.
The Journal of biological chemistry 2002;277(49):47044-51.
2002: Joost G J Hoenderop; Bernd Nilius; René J M Bindels
ECaC: the gatekeeper of transepithelial Ca2+ transport.
Biochimica et biophysica acta 2002;1600(1-2):6-11.
2002: Thomas Voets; Jean Prenen; Joris Vriens; Hiroyuki Watanabe; Annelies Janssens; Ulrich Wissenbach; Matthias Bödding; Guy Droogmans; Bernd Nilius
Molecular determinants of permeation through the cation channel TRPV4.
The Journal of biological chemistry 2002;277(37):33704-10.
2002: Dominik Müller; Joost G J Hoenderop; Rudi Vennekens; Paul Eggert; Ferenc Harangi; Károly Méhes; Victor Garcia-Nieto; Felix Claverie-Martin; Carel H van Os; Bernd Nilius; René J M Bindels
Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(9):1614-20.
2002: Bernd Nilius; Jean Prenen; Joost G J Hoenderop; Rudi Vennekens; Susan Hoefs; A Freek Weidema; Guy Droogmans; René J M Bindels
Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.
The Journal of biological chemistry 2002;277(34):30852-8.
2002: Chantal Maertens; Guy Droogmans; Rene Verbesselt; Bernd Nilius
Block of volume-regulated anion channels by selective serotonin reuptake inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):158-65.
2002: Emese Toth-Zsamboki; Cécile Oury; Hiroyuki Watanabe; Bernd Nilius; Jos Vermylen; Marc F Hoylaerts
The intracellular tyrosine residues of the ATP-gated P2X(1) ion channel are essential for its function.
FEBS letters 2002;524(1-3):15-9.
2002: Iris Carton; Dominique Trouet; Diane Hermans; Holger Barth; Klaus Aktories; Guy Droogmans; Nanna K Jorgensen; Else Hoffmann; Bernd Nilius; Jan Eggermont
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.
American journal of physiology. Cell physiology 2002;283(1):C115-25.
2002: Suk H Suh; Hiroyuki Watanabe; Guy Droogmans; Bernd Nilius
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 2002;444(3):438-45.
2002: Rudi Vennekens; Thomas Voets; René J M Bindels; Guy Droogmans; Bernd Nilius
Current understanding of mammalian TRP homologues.
Cell calcium 2002;31(6):253-64.
2002: Hiroyuki Watanabe; John B Davis; Darren Smart; Jeffrey C Jerman; Graham D Smith; Phil Hayes; Joris Vriens; William Cairns; Ulrich Wissenbach; Jean Prenen; Veit Flockerzi; Guy Droogmans; Christopher D Benham; Bernd Nilius
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
The Journal of biological chemistry 2002;277(16):13569-77.
2002: Loïc Lemonnier; Natalia Prevarskaya; Yaroslav Shuba; Fabien Vanden Abeele; Bernd Nilius; Joel Mazurier; Roman Skryma
Ca2+ modulation of volume-regulated anion channels: evidence for colocalization with store-operated channels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):222-4.
2002: Luc Raeymaekers; Bernd Nilius; Thomas Voets; Ludwig Missiaen; Kurt Van Baelen; Jo Vanoevelen; Frank Wuytack
Additional fluxes of activator Ca2+ accompanying Ca2+ release from the sarcoplasmic reticulum triggered by insP3-mobilizing agonists.
Novartis Foundation symposium 2002;246():71-6; discussion 76-80, 221-7.
2002: Joost G J Hoenderop; Bernd Nilius; René J M Bindels
Molecular mechanism of active Ca2+ reabsorption in the distal nephron.
Annual review of physiology 2002;64():529-49.
2001: Thomas Voets; Jean Prenen; Andrea Fleig; Rudi Vennekens; Hiroyuki Watanabe; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Reinhold Penner; Bernd Nilius
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties.
The Journal of biological chemistry 2001;276(51):47767-70.
2001: Joost G J Hoenderop; Rudi Vennekens; Dominik Müller; Jean Prenen; Guy Droogmans; René J M Bindels; Bernd Nilius
Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2.
The Journal of physiology 2001;537(Pt 3):747-61.
2001: Karel Talavera; Mik Staes; Annelies Janssens; Norbert Klugbauer; Guy Droogmans; Franz Hofmann; Bernd Nilius
Aspartate residues of the Glu-Glu-Asp-Asp (EEDD) pore locus control selectivity and permeation of the T-type Ca(2+) channel alpha(1G).
The Journal of biological chemistry 2001;276(49):45628-35.
2001: Niels Decher; Hans-Jochen Lang; Bernd Nilius; Andrea Bruggemann; Andreas E Busch; Klaus Steinmeyer
DCPIB is a novel selective blocker of I(Cl,swell) and prevents swelling-induced shortening of guinea-pig atrial action potential duration.
British journal of pharmacology 2001;134(7):1467-79.
2001: Bernd Nilius; Jean Prenen; Ulrich Wissenbach; Matthias Bödding; Guy Droogmans
Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells.
Pflügers Archiv : European journal of physiology 2001;443(2):227-33.
2001: Bernd Nilius; Jean Prenen; Rudi Vennekens; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1.
British journal of pharmacology 2001;134(3):453-62.
2001: Bernd Nilius; G Droogmans
Ion channels and their functional role in vascular endothelium.
Physiological reviews 2001;81(4):1415-59.
2001: Rudi Vennekens; Guy Droogmans; Bernd Nilius
Functional properties of the epithelial Ca2+ channel, ECaC.
General physiology and biophysics 2001;20(3):239-53.
2001: Dominique Trouet; Iris Carton; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of VRAC by c-Src tyrosine kinase targeted to caveolae is mediated by the Src homology domains.
American journal of physiology. Cell physiology 2001;281(1):C248-56.
2001: K Kielbassa-Schnepp; Anke Strey; Annette Janning; L Missiaen; Bernd Nilius; Volker Gerke
Endothelial intracellular Ca2+ release following monocyte adhesion is required for the transendothelial migration of monocytes.
Cell calcium 2001;30(1):29-40.
2001: Dominique Trouet; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of volume-regulated anion channels by dominant-negative caveolin-1.
Biochemical and biophysical research communications 2001;284(2):461-5.
2001: Bernd Nilius; Jean Prenen; Rudi Vennekens; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+.
Cell calcium 2001;29(6):417-28.
2001: L Wei; Anne Vankeerberghen; Harry Cuppens; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
The C-terminal part of the R-domain, but not the PDZ binding motif, of CFTR is involved in interaction with Ca(2+)-activated Cl- channels.
Pflügers Archiv : European journal of physiology 2001;442(2):280-5.
2001: J Papassotiriou; Jan Eggermont; Guy Droogmans; Bernd Nilius
Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3.
Pflügers Archiv : European journal of physiology 2001;442(2):273-9.
2001: Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Bernd Nilius
Modulation of the epithelial Ca2+ channel ECaC by extracellular pH.
Pflügers Archiv : European journal of physiology 2001;442(2):237-42.
2001: Bernd Nilius
Chloride channels go cell cycling.
The Journal of physiology 2001;532(Pt 3):581.
2001: Marc Freichel; S H Suh; A Pfeifer; U Schweig; Claudia Trost; Petra Weissgerber; M Biel; Stephan E Philipp; Doris Freise; Guy Droogmans; Franz Hofmann; Veit Flockerzi; Bernd Nilius
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.
Nature cell biology 2001;3(2):121-7.
2001: Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans; Bernd Nilius
Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells.
The Journal of physiology 2001;530(Pt 2):183-91.
2001: Bernd Nilius; Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; Guy Droogmans; René J M Bindels
The single pore residue Asp542 determines Ca2+ permeation and Mg2+ block of the epithelial Ca2+ channel.
The Journal of biological chemistry 2001;276(2):1020-5.
2001: Jan Eggermont; Dominique Trouet; Iris Carton; Bernd Nilius
Cellular function and control of volume-regulated anion channels.
Cell biochemistry and biophysics 2001;35(3):263-74.
2001: L Wei; Marc Freichel; Martine Jaspers; Harry Cuppens; Jean-Jacques Cassiman; Guy Droogmans; Veit Flockerzi; Bernd Nilius
Functional interaction between TRP4 and CFTR in mouse aorta endothelial cells.
BMC physiology 2001;1():3.
2001: Chantal Maertens; Guy Droogmans; P Chakraborty; Bernd Nilius
Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine.
British journal of pharmacology 2001;132(1):135-42.
2001: Mik Staes; Karel Talavera; Norbert Klugbauer; Jean Prenen; Lubica Lacinova; Guy Droogmans; Franz Hofmann; Bernd Nilius
The amino side of the C-terminus determines fast inactivation of the T-type calcium channel alpha1G.
The Journal of physiology 2001;530(Pt 1):35-45.
2000: Meng-Ru Shen; Guy Droogmans; Jan Eggermont; Thomas Voets; J Clive Ellory; Bernd Nilius
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells.
The Journal of physiology 2000;529 Pt 2():385-94.
2000: Chantal Maertens; L Wei; Guy Droogmans; Bernd Nilius
Inhibition of volume-regulated and calcium-activated chloride channels by the antimalarial mefloquine.
The Journal of pharmacology and experimental therapeutics 2000;295(1):29-36.
2000: Bernd Nilius; Rudi Vennekens; Jean Prenen; Joost G J Hoenderop; René J M Bindels; Guy Droogmans
Whole-cell and single channel monovalent cation currents through the novel rabbit epithelial Ca2+ channel ECaC.
The Journal of physiology 2000;527 Pt 2():239-48.
2000: R Z Sabirov; Jean Prenen; Guy Droogmans; Bernd Nilius
Extra- and intracellular proton-binding sites of volume-regulated anion channels.
The Journal of membrane biology 2000;177(1):13-22.
2000: Cécile Oury; Emese Toth-Zsamboki; Chris Van Geet; Chantal Thys; L Wei; Bernd Nilius; Jos Vermylen; Marc F Hoylaerts
A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue.
The Journal of biological chemistry 2000;275(30):22611-4.
2000: L Missiaen; W Robberecht; Ludo Van Den Bosch; Geert Callewaert; Jan B Parys; Frank Wuytack; Luc Raeymaekers; Bernd Nilius; Jan Eggermont; H De Smedt
Abnormal intracellular ca(2+)homeostasis and disease.
Cell calcium 2000;28(1):1-21.
2000: Carsten A Wagner; Stephan M Huber; Simone Wärntges; G Zempel; NK Kaba; R Fux; N Orth; GL Busch; Siegfried Waldegger; I Lambert; Bernd Nilius; Helmut Heinle; Florian Lang
Effect of urea and osmotic cell shrinkage on Ca2+ entry and contraction of vascular smooth muscle cells.
Pflügers Archiv : European journal of physiology 2000;440(2):295-301.
2000: L Wei; Anne Vankeerberghen; Martine Jaspers; Jean-Jacques Cassiman; Bernd Nilius; Harry Cuppens
Suppressive interactions between mutations located in the two nucleotide binding domains of CFTR.
FEBS letters 2000;473(2):149-53.
2000: J Papassotiriou; Ralf Köhler; Jean Prenen; Hans Krause; M Akbar; Jan Eggermont; Martin Paul; Armin Distler; Bernd Nilius; Joachim Hoyer
Endothelial K(+) channel lacks the Ca(2+) sensitivity-regulating beta subunit.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):885-94.
2000: Rudi Vennekens; Joost G J Hoenderop; Jean Prenen; M Stuiver; P H Willems; Guy Droogmans; Bernd Nilius; René J M Bindels
Permeation and gating properties of the novel epithelial Ca(2+) channel.
The Journal of biological chemistry 2000;275(6):3963-9.
2000: VG Manolopoulos; S Liekens; PIETER KOOLWIJK; Thomas Voets; E Peters; Guy Droogmans; Peter Lelkes; E De Clercq; Bernd Nilius
Inhibition of angiogenesis by blockers of volume-regulated anion channels.
General pharmacology 2000;34(2):107-16.
2000: Chantal Maertens; L Wei; Jan Tytgat; Guy Droogmans; Bernd Nilius
Chlorotoxin does not inhibit volume-regulated, calcium-activated and cyclic AMP-activated chloride channels.
British journal of pharmacology 2000;129(4):791-801.
2000: Bernd Nilius; Jean Prenen; M P Walsh; Iris Carton; M Bollen; Guy Droogmans; Jan Eggermont
Myosin light chain phosphorylation-dependent modulation of volume-regulated anion channels in macrovascular endothelium.
FEBS letters 2000;466(2-3):346-50.
2000: Ludwig Missiaen; Geert Callewaert; Jan B Parys; Frank Wuytack; Luc Raeymaekers; G Droogmans; Bernd Nilius; Jan Eggermont; Humbert De Smedt
[Intracellular calcium: physiology and physiopathology].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2000;62(6):471-99.
2000: Bernd Nilius; Jan Eggermont; G Droogmans
The endothelial volume-regulated anion channel, VRAC.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):313-20.
2000: S H Suh; Guy Droogmans; Bernd Nilius
Effects of cyanide and deoxyglucose on Ca2+ signalling in macrovascular endothelial cells.
Endothelium : journal of endothelial cell research 2000;7(3):155-68.
2000: R Z Sabirov; Jean Prenen; T Tomita; G Droogmans; Bernd Nilius
Reduction of ionic strength activates single volume-regulated anion channels (VRAC) in endothelial cells.
Pflügers Archiv : European journal of physiology 2000;439(3):315-20.
1999: Anne Vankeerberghen; W Lin; Martine Jaspers; Harry Cuppens; Bernd Nilius; Jean-Jacques Cassiman
Functional characterization of the CFTR R domain using CFTR/MDR1 hybrid and deletion constructs.
Biochemistry 1999;38(45):14988-98.
1999: L Wei; Anne Vankeerberghen; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Interaction between calcium-activated chloride channels and the cystic fibrosis transmembrane conductance regulator.
Pflügers Archiv : European journal of physiology 1999;438(5):635-41.
1999: Suk H Suh; Rudi Vennekens; VG Manolopoulos; Marc Freichel; U Schweig; Jean Prenen; Veit Flockerzi; Guy Droogmans; Bernd Nilius
Characterisation of explanted endothelial cells from mouse aorta: electrophysiology and Ca2+ signalling.
Pflügers Archiv : European journal of physiology 1999;438(5):612-20.
1999: Dominique Trouet; Bernd Nilius; A Jacobs; C Remacle; Guy Droogmans; Jan Eggermont
Caveolin-1 modulates the activity of the volume-regulated chloride channel.
The Journal of physiology 1999;520 Pt 1():113-9.
1999: Guy Droogmans; Chantal Maertens; Jean Prenen; Bernd Nilius
Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells.
British journal of pharmacology 1999;128(1):35-40.
1999: M Kamouchi; Stephan E Philipp; Veit Flockerzi; Ulrich Wissenbach; A Mamin; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1999;518 Pt 2():345-58.
1999: M Kamouchi; Guy Droogmans; Bernd Nilius
Membrane potential as a modulator of the free intracellular Ca2+ concentration in agonist-activated endothelial cells.
General physiology and biophysics 1999;18(2):199-208.
1999: Florian Lang; Anne-Catrin Uhlemann; Albrecht Lepple-Wienhues; Ildiko Szabo; Detlef Siemen; Bernd Nilius; Erich Gulbins
Cell volume regulatory mechanisms in apoptotic cell death.
Herz 1999;24(3):232-5.
1999: M Kamouchi; A Mamin; Guy Droogmans; Bernd Nilius
Nonselective cation channels in endothelial cells derived from human umbilical vein.
The Journal of membrane biology 1999;169(1):29-38.
1999: Thomas Voets; Guy Droogmans; G Raskin; Jan Eggermont; Bernd Nilius
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5298-303.
1999: S Junge; Birgit Brenner; Albrecht Lepple-Wienhues; Bernd Nilius; Florian Lang; Otwin Linderkamp; Erich Gulbins
Intracellular mechanisms of L-selectin induced capping.
Cellular signalling 1999;11(4):301-8.
1999: Bernd Nilius; Thomas Voets; Jean Prenen; H Barth; Klaus Aktories; K Kaibuchi; Guy Droogmans; Jan Eggermont
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.
The Journal of physiology 1999;516 ( Pt 1)():67-74.
1999: M Boegehold; R M Lee; M J Mulvany; Bernd Nilius; R L Prewitt; J Zhang
Vascular research at INABIS 98.
Journal of vascular research 1999;36(2):147-50.
1999: Rudi Vennekens; Dominique Trouet; Anne Vankeerberghen; Thomas Voets; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Inhibition of volume-regulated anion channels by expression of the cystic fibrosis transmembrane conductance regulator.
The Journal of physiology 1999;515 ( Pt 1)():75-85.
1999: S Pedersen; Stine F Pedersen; Bernd Nilius; Ian H Lambert; Else Hoffmann
Mechanical stress induces release of ATP from Ehrlich ascites tumor cells.
Biochimica et biophysica acta 1999;1416(1-2):271-84.
1999: Chantal Maertens; L Wei; Thomas Voets; Guy Droogmans; Bernd Nilius
Block by fluoxetine of volume-regulated anion channels.
British journal of pharmacology 1999;126(2):508-14.
1998: L Wei; Anne Vankeerberghen; Harry Cuppens; Guy Droogmans; Jean-Jacques Cassiman; Bernd Nilius
Phosphorylation site independent single R-domain mutations affect CFTR channel activity.
FEBS letters 1998;439(1-2):121-6.
1998: Anne Vankeerberghen; L Wei; H Teng; Martine Jaspers; Jean-Jacques Cassiman; Bernd Nilius; Harry Cuppens
Characterization of mutations located in exon 18 of the CFTR gene.
FEBS letters 1998;437(1-2):1-4.
1998: Anne Vankeerberghen; L Wei; Martine Jaspers; Jean-Jacques Cassiman; Bernd Nilius; Harry Cuppens
Characterization of 19 disease-associated missense mutations in the regulatory domain of the cystic fibrosis transmembrane conductance regulator.
Human molecular genetics 1998;7(11):1761-9.
1998: Bernd Nilius; Jean Prenen; Guy Droogmans
Modulation of volume-regulated anion channels by extra- and intracellular pH.
Pflügers Archiv : European journal of physiology 1998;436(5):742-8.
1998: Guy Droogmans; Jean Prenen; Jan Eggermont; Thomas Voets; Bernd Nilius
Voltage-dependent block of endothelial volume-regulated anion channels by calix[4]arenes.
The American journal of physiology 1998;275(3 Pt 1):C646-52.
1998: Felix Viana; Humbert De Smedt; Guy Droogmans; Bernd Nilius
Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium.
Cell calcium 1998;24(2):117-27.
1998: J König; J Prenen; Bernd Nilius; Volker Gerke
The annexin II-p11 complex is involved in regulated exocytosis in bovine pulmonary artery endothelial cells.
The Journal of biological chemistry 1998;273(31):19679-84.
1998: Cristina Fasolato; Bernd Nilius
Store depletion triggers the calcium release-activated calcium current (ICRAC) in macrovascular endothelial cells: a comparison with Jurkat and embryonic kidney cell lines.
Pflügers Archiv : European journal of physiology 1998;436(1):69-74.
1998: Stine F Pedersen; J Prenen; G Droogmans; Else Hoffmann; Bernd Nilius
Separate swelling- and Ca2+-activated anion currents in Ehrlich ascites tumor cells.
The Journal of membrane biology 1998;163(2):97-110.
1998: Thomas Voets; Gunnar Buyse; Guy Droogmans; Jan Eggermont; Bernd Nilius
The GXGXG motif in the pI(Cln) protein is not important for the nucleotide sensitivity of the pI(Cln)-induced Cl- current in Xenopus oocytes.
FEBS letters 1998;426(2):171-3.
1998: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Guy Droogmans; Bernd Nilius
Is there a link between protein pICln and volume-regulated anion channels?
The Biochemical journal 1998;331 ( Pt 1)():347-9.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Karol S Bruzik; Stephen B Shears; Guy Droogmans
Inhibition by inositoltetrakisphosphates of calcium- and volume-activated Cl- currents in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 1998;435(5):637-44.
1998: Gunnar Buyse; Dominique Trouet; Thomas Voets; Ludwig Missiaen; Guy Droogmans; Bernd Nilius; Jan Eggermont
Evidence for the intracellular location of chloride channel (ClC)-type proteins: co-localization of ClC-6a and ClC-6c with the sarco/endoplasmic-reticulum Ca2+ pump SERCA2b.
The Biochemical journal 1998;330 ( Pt 2)():1015-21.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Guy Droogmans
Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells.
The Journal of physiology 1998;506 ( Pt 2)():353-61.
1998: Thomas Voets; VG Manolopoulos; Jan Eggermont; C Ellory; Guy Droogmans; Bernd Nilius
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins.
The Journal of physiology 1998;506 ( Pt 2)():341-52.
1998: Harry Cuppens; W Lin; Martine Jaspers; Bruno Costes; H Teng; Anne Vankeerberghen; Mark Jorissen; Guy Droogmans; I Reynaert; Michel Goossens; Bernd Nilius; Jean-Jacques Cassiman
Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation.
The Journal of clinical investigation 1998;101(2):487-96.
1998: Bernd Nilius
Signaltransduction in vascular endothelium: the role of intracellular calcium and ion channels.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1998;60(3):215-50.
1997: M Kamouchi; Dominique Trouet; C De Greef; Guy Droogmans; Jan Eggermont; Bernd Nilius
Functional effects of expression of hslo Ca2+ activated K+ channels in cultured macrovascular endothelial cells.
Cell calcium 1997;22(6):497-506.
1997: M Kamouchi; K Van Den Bremt; Jan Eggermont; Guy Droogmans; Bernd Nilius
Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;504 ( Pt 3)():545-56.
1997: Felix Viana; Ludo Van Den Bosch; Ludwig Missiaen; Wim Vandenberghe; Guy Droogmans; Bernd Nilius; Wim Robberecht
Mibefradil (Ro 40-5967) blocks multiple types of voltage-gated calcium channels in cultured rat spinal motoneurones.
Cell calcium 1997;22(4):299-311.
1997: Thomas Voets; Guy Droogmans; Bernd Nilius
Modulation of voltage-dependent properties of a swelling-activated Cl- current.
The Journal of general physiology 1997;110(3):313-25.
1997: Dominique Trouet; Bernd Nilius; Thomas Voets; Guy Droogmans; Jan Eggermont
Use of a bicistronic GFP-expression vector to characterise ion channels after transfection in mammalian cells.
Pflügers Archiv : European journal of physiology 1997;434(5):632-8.
1997: VG Manolopoulos; Thomas Voets; Peter E Declercq; Guy Droogmans; Bernd Nilius
Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells.
The American journal of physiology 1997;273(1 Pt 1):C214-22.
1997: Bernd Nilius; Jean Prenen; Thomas Voets; K Van den Bremt; Jan Eggermont; Guy Droogmans
Kinetic and pharmacological properties of the calcium-activated chloride-current in macrovascular endothelial cells.
Cell calcium 1997;22(1):53-63.
1997: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Humbert De Smedt; Guy Droogmans; Bernd Nilius
Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.
The Biochemical journal 1997;325 ( Pt 1)():269-76.
1997: Bernd Nilius; Jean Prenen; M Kamouchi; Felix Viana; Thomas Voets; Guy Droogmans
Inhibition by mibefradil, a novel calcium channel antagonist, of Ca(2+)- and volume-activated Cl- channels in macrovascular endothelial cells.
British journal of pharmacology 1997;121(3):547-55.
1997: Bernd Nilius; G Szücs; S Heinke; Thomas Voets; Guy Droogmans
Multiple types of chloride channels in bovine pulmonary artery endothelial cells.
Journal of vascular research 1997;34(3):220-8.
1997: M Haburcák; L Wei; Felix Viana; Jean Prenen; Guy Droogmans; Bernd Nilius
Calcium-activated potassium channels in cultured human endothelial cells are not directly modulated by nitric oxide.
Cell calcium 1997;21(4):291-300.
1997: G V Manolopoulos; Jean Prenen; Guy Droogmans; Bernd Nilius
Thrombin potentiates volume-activated chloride currents in pulmonary artery endothelial cells.
Pflügers Archiv : European journal of physiology 1997;433(6):845-7.
1997: VG Manolopoulos; Guy Droogmans; Bernd Nilius
Hypotonicity and thrombin activate taurine efflux in BC3H1 and C2C12 myoblasts that is down regulated during differentiation.
Biochemical and biophysical research communications 1997;232(1):74-9.
1997: I Szabó; Bernd Nilius; X Zhang; Andreas E Busch; Erich Gulbins; Hartmut Suessbrich; Florian Lang
Inhibitory effects of oxidants on n-type K+ channels in T lymphocytes and Xenopus oocytes.
Pflügers Archiv : European journal of physiology 1997;433(5):626-32.
1997: Gunnar Buyse; Thomas Voets; Jan Tytgat; C De Greef; Guy Droogmans; Bernd Nilius; Jan Eggermont
Expression of human pICln and ClC-6 in Xenopus oocytes induces an identical endogenous chloride conductance.
The Journal of biological chemistry 1997;272(6):3615-21.
1997: Thomas Voets; L Wei; Patrick De Smet; Willy Van Driessche; Jan Eggermont; Guy Droogmans; Bernd Nilius
Downregulation of volume-activated Cl- currents during muscle differentiation.
The American journal of physiology 1997;272(2 Pt 1):C667-74.
1997: Bernd Nilius; Jean Prenen; G Szücs; L Wei; F Tanzi; Thomas Voets; Guy Droogmans
Calcium-activated chloride channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;498 ( Pt 2)():381-96.
1997: Bernd Nilius; Jan Eggermont; Thomas Voets; Gunnar Buyse; VG Manolopoulos; Guy Droogmans
Properties of volume-regulated anion channels in mammalian cells.
Progress in biophysics and molecular biology 1997;68(1):69-119.
1997: Bernd Nilius; Felix Viana; Guy Droogmans
Ion channels in vascular endothelium.
Annual review of physiology 1997;59():145-70.
1996: Bernd Nilius; Volker Gerke; Jean Prenen; G Szücs; S Heinke; K Weber; Guy Droogmans
Annexin II modulates volume-activated chloride currents in vascular endothelial cells.
The Journal of biological chemistry 1996;271(48):30631-6.
1996: Thomas Voets; Guy Droogmans; Bernd Nilius
Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1996;497 ( Pt 1)():95-107.
1996: Bernd Nilius; Jan Eggermont; Thomas Voets; G Droogmans
Volume-activated Cl- channels.
General pharmacology 1996;27(7):1131-40.
1996: Thomas Voets; Gunnar Buyse; Jan Tytgat; Guy Droogmans; Jan Eggermont; Bernd Nilius
The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume-sensitive chloride current.
The Journal of physiology 1996;495 ( Pt 2)():441-7.
1996: Thomas Voets; Guy Droogmans; Bernd Nilius
Potent block of volume-activated chloride currents in endothelial cells by the uncharged form of quinine and quinidine.
British journal of pharmacology 1996;118(7):1869-71.
1996: Jan Tytgat; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius; P Daenens
Do voltage-gated Kv1.1 and inward rectifier Kir2.1 potassium channels form heteromultimers?
FEBS letters 1996;390(3):280-4.
1996: Ludwig Missiaen; Humbert De Smedt; Jan B Parys; Ilse Sienaert; Sara Vanlingen; G Droogmans; Bernd Nilius; Rik Casteels
Hypotonically induced calcium release from intracellular calcium stores.
The Journal of biological chemistry 1996;271(9):4601-4.
1996: G Szücs; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius
Characterization of volume-activated chloride currents in endothelial cells from bovine pulmonary artery.
The Journal of membrane biology 1996;149(3):189-97.
1996: G Szücs; S Heinke; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
The volume-activated chloride current in endothelial cells from bovine pulmonary artery is not modulated by phosphorylation.
Pflügers Archiv : European journal of physiology 1996;431(4):540-8.
1996: Gunnar Buyse; C De Greef; Luc Raeymaekers; Guy Droogmans; Bernd Nilius; Jan Eggermont
The ubiquitously expressed pICln protein forms homomeric complexes in vitro.
Biochemical and biophysical research communications 1996;218(3):822-7.
1996: G Szücs; S Heinke; Guy Droogmans; Bernd Nilius
Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration.
Pflügers Archiv : European journal of physiology 1996;431(3):467-9.
1995: Thomas Voets; G Szücs; Guy Droogmans; Bernd Nilius
Blockers of volume-activated Cl- currents inhibit endothelial cell proliferation.
Pflügers Archiv : European journal of physiology 1995;431(1):132-4.
1995: Bernd Nilius; J Sehrer; Patrick De Smet; Willy Van Driessche; Guy Droogmans
Volume regulation in a toad epithelial cell line: role of coactivation of K+ and Cl- channels.
The Journal of physiology 1995;487 ( Pt 2)():367-78.
1995: S Heinke; G Szücs; A Norris; Guy Droogmans; Bernd Nilius
Inhibition of volume-activated chloride currents in endothelial cells by chromones.
British journal of pharmacology 1995;115(8):1393-8.
1995: Bernd Nilius; J Sehrer; S Heinke; Guy Droogmans
Ca2+ release and activation of K+ and Cl- currents by extracellular ATP in distal nephron epithelial cells.
The American journal of physiology 1995;269(2 Pt 1):C376-84.
1995: C De Greef; S van der Heyden; Felix Viana; Jan Eggermont; Ernst A de Bruijn; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Lack of correlation between mdr-1 expression and volume-activation of cloride-currents in rat colon cancer cells.
Pflügers Archiv : European journal of physiology 1995;430(2):296-8.
1995: C De Greef; J Sehrer; Felix Viana; K van Acker; Jan Eggermont; Luc Mertens; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Volume-activated chloride currents are not correlated with P-glycoprotein expression.
The Biochemical journal 1995;307 ( Pt 3)():713-8.
1995: Felix Viana; K Van Acker; C De Greef; Jan Eggermont; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Drug-transport and volume-activated chloride channel functions in human erythroleukemia cells: relation to expression level of P-glycoprotein.
The Journal of membrane biology 1995;145(1):87-98.
1995: M Gericke; O Dar; Guy Droogmans; I Pecht; Bernd Nilius
Immunological stimulation of single rat basophilic leukemia RBL-2H3 cells co-activates Ca(2+)-entry and K(+)-channels.
Cell calcium 1995;17(1):71-83.
1994: M Gericke; M Oike; Guy Droogmans; Bernd Nilius
Inhibition of capacitative Ca2+ entry by a Cl- channel blocker in human endothelial cells.
European journal of pharmacology 1994;269(3):381-4.
1994: M Oike; M Gericke; Guy Droogmans; Bernd Nilius
Calcium entry activated by store depletion in human umbilical vein endothelial cells.
Cell calcium 1994;16(5):367-76.
1994: M Oike; G Schwarz; J Sehrer; M Jost; Volker Gerke; K Weber; Guy Droogmans; Bernd Nilius
Cytoskeletal modulation of the response to mechanical stimulation in human vascular endothelial cells.
Pflügers Archiv : European journal of physiology 1994;428(5-6):569-76.
1994: Bernd Nilius; J Sehrer; Felix Viana; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans
Volume-activated Cl- currents in different mammalian non-excitable cell types.
Pflügers Archiv : European journal of physiology 1994;428(3-4):364-71.
1994: Patrick De Smet; M Oike; Guy Droogmans; Willy Van Driessche; Bernd Nilius
Responses of endothelial cells to hypotonic solutions: lack of regulatory volume decrease.
Pflügers Archiv : European journal of physiology 1994;428(1):94-6.
1994: Bernd Nilius; J Sehrer; Guy Droogmans
Permeation properties and modulation of volume-activated Cl(-)-currents in human endothelial cells.
British journal of pharmacology 1994;112(4):1049-56.
1994: M Oike; Guy Droogmans; Bernd Nilius
Amplitude modulation of Ca2+ signals induced by histamine in human endothelial cells.
Biochimica et biophysica acta 1994;1222(2):287-91.
1994: M Oike; G Droogmans; Bernd Nilius
The volume-activated chloride current in human endothelial cells depends on intracellular ATP.
Pflügers Archiv : European journal of physiology 1994;427(1-2):184-6.
1994: Bernd Nilius; M Oike; Ivan Zahradník; Guy Droogmans
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
The Journal of general physiology 1994;103(5):787-805.
1994: M Oike; Guy Droogmans; Bernd Nilius
Mechanosensitive Ca2+ transients in endothelial cells from human umbilical vein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):2940-4.
1994: Bernd Nilius; K Kitamura; H Kuriyama
Properties of inactivation of calcium channel currents in smooth muscle cells of rabbit portal vein.
Pflügers Archiv : European journal of physiology 1994;426(3-4):239-46.
1994: G Schwarz; Guy Droogmans; Bernd Nilius
Multiple effects of SK&F 96365 on ionic currents and intracellular calcium in human endothelial cells.
Cell calcium 1994;15(1):45-54.
1993: Bernd Nilius; G Schwarz; Guy Droogmans
Control of intracellular calcium by membrane potential in human melanoma cells.
The American journal of physiology 1993;265(6 Pt 1):C1501-10.
1993: Bernd Nilius; G Schwarz; Guy Droogmans
Modulation by histamine of an inwardly rectifying potassium channel in human endothelial cells.
The Journal of physiology 1993;472():359-71.
1993: M Oike; G Droogmans; R Casteels; Bernd Nilius
Electrogenic Na+/K(+)-transport in human endothelial cells.
Pflügers Archiv : European journal of physiology 1993;424(3-4):301-7.
1993: Bernd Nilius; G Schwartz; M Oike; Guy Droogmans
Histamine-activated, non-selective cation currents and Ca2+ transients in endothelial cells from human umbilical vein.
Pflügers Archiv : European journal of physiology 1993;424(3-4):285-93.
1993: M Gericke; G Droogmans; Bernd Nilius
Thimerosal induced changes of intracellular calcium in human endothelial cells.
Cell calcium 1993;14(3):201-7.
1993: M Gericke; G Droogmans; Bernd Nilius
Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells.
Pflügers Archiv : European journal of physiology 1993;422(6):552-7.
1993: F Scamps; Bernd Nilius; J Alvarez; Guy Vassort
Modulation of L-type Ca channel activity by P2-purinergic agonist in cardiac cells.
Pflügers Archiv : European journal of physiology 1993;422(5):465-71.
1993: Bernd Nilius; Guy Droogmans; M Gericke; G Schwarz
Nonselective ion pathways in human endothelial cells.
EXS 1993;66():269-80.
1992: G Schwarz; G Callewaert; G Droogmans; Bernd Nilius
Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins.
The Journal of physiology 1992;458():527-38.
1992: G Schwarz; G Droogmans; Bernd Nilius
Shear stress induced membrane currents and calcium transients in human vascular endothelial cells.
Pflügers Archiv : European journal of physiology 1992;421(4):394-6.
1990: Jan Tytgat; Bernd Nilius; E Carmeliet
Modulation of the T-type cardiac Ca channel by changes in proton concentration.
The Journal of general physiology 1990;96(5):973-90.
1990: Laszlo Csernoch; László Kovács; Bernd Nilius; G Szücs
Caffeine and the myoplasmic calcium removal mechanisms in cut frog skeletal muscle fibres.
General physiology and biophysics 1990;9(3):251-66.
1989: Guy Droogmans; Bernd Nilius
Kinetic properties of the cardiac T-type calcium channel in the guinea-pig.
The Journal of physiology 1989;419():627-50.
1988: Jan Tytgat; Bernd Nilius; J Vereecke; Edward Carmeliet
The T-type Ca channel in guinea-pig ventricular myocytes is insensitive to isoproterenol.
Pflügers Archiv : European journal of physiology 1988;411(6):704-6.
1987: Richard W Tsien; Aaron P Fox; P Hess; E W McCleskey; Bernd Nilius; M C Nowycky; R L Rosenberg
Multiple types of calcium channel in excitable cells.
Society of General Physiologists series 1987;41():167-87.
1986: Andreas Reichenbach; Bernd Nilius; W Eberhardt
Potassium accumulation by the glial membrane pump as revealed by membrane potential recording from isolated rabbit retinal Müller cells.
Neuroscience letters 1986;63(3):280-4.