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Jan Potempa
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93
Travis, James
13
Banbula, Agnieszka
13
Pike, Robert
11
Dubin, Adam
9
Enghild, Jan
9
Imamura, Takahisa
9
Travis, James
8
Dubin, Grzegorz
7
Bugno, Marcin
7
Bzowska, Malgorzata
7
Cichy, Joanna
7
Filipek, Renata
7
Genco, Caroline Attardo
7
Nelson, Daniel
7
Sabat, Artur
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All Publications
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2009: Monteiro Ana Carolina; Scovino Aline; Raposo Susane; Gaze Vinicius Mussa; Cruz Catia; Svensjö Erik; Narciso Marcelo Sampaio; Colombo Ana Paula; Pesquero João B; Feres-Filho Eduardo; Nguyen Ky-Anh; Sroka Aneta; Potempa Jan; Scharfstein Julio
Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):3700-11.
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2009: Fitzpatrick R E; Campbell P D; Sivagurunathan S; Pagel C N; Potempa J; Mackie E J; Pike R N
The gingipains from Porphyromonas gingivalis do not directly induce osteoclast differentiation in primary mouse bone marrow cultures.
Journal of periodontal research 2009;44(4):565-7.
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2009: Guentsch A; Puklo M; Preshaw P M; Glockmann E; Pfister W; Potempa J; Eick S
Neutrophils in chronic and aggressive periodontitis in interaction with Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.
Journal of periodontal research 2009;44(3):368-77.
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2009: McAlister A D; Sroka A; Fitzpatrick R E; Quinsey N S; Travis J; Potempa J; Pike R N
Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization?
Journal of periodontal research 2009;44(3):348-53.
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2009: Wójtowicz Halina; Guevara Tibisay; Tallant Cynthia; Olczak Mariusz; Sroka Aneta; Potempa Jan; Solà Maria; Olczak Teresa; Gomis-Rüth F Xavier
Unique structure and stability of HmuY, a novel heme-binding protein of Porphyromonas gingivalis.
PLoS pathogens 2009;5(5):e1000419.
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2009: Stec-Niemczyk Justyna; Pustelny Katarzyna; Kisielewska Magdalena; Bista Michal; Boulware Kevin T; Stennicke Henning R; Thogersen Ida B; Daugherty Patrick S; Enghild Jan J; Baczynski Krzysztof; Popowicz Grzegorz M; Dubin Adam; Potempa Jan; Dubin Grzegorz
Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus.
The Biochemical journal 2009;419(3):555-64.
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2009: Smagur Jan; Guzik Krzysztof; Bzowska Malgorzata; Kuzak Mateusz; Zarebski Miroslaw; Kantyka Tomasz; Walski Michal; Gajkowska Barbara; Potempa Jan
Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages.
Biological chemistry 2009;390(4):361-71.
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2009: Potempa Michal; Potempa Jan; Kantyka Tomasz; Nguyen Ky-Anh; Wawrzonek Katarzyna; Manandhar Surya P; Popadiak Katarzyna; Riesbeck Kristian; Eick Sigrun; Blom Anna M
Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3.
PLoS pathogens 2009;5(2):e1000316.
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2009: Nguyen Ky-Anh; Zylicz Jasiek; Szczesny Pawel; Sroka Aneta; Hunter Neil; Potempa Jan
Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis.
Microbiology (Reading, England) 2009;155(Pt 2):328-37.
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2009: Koziel Joanna; Maciag-Gudowska Agnieszka; Mikolajczyk Tomasz; Bzowska Malgorzata; Sturdevant Daniel E; Whitney Adeline R; Shaw Lindsey N; DeLeo Frank R; Potempa Jan
Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors.
PloS one 2009;4(4):e5210.
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2008: Potempa Michal; Potempa Jan; Okroj Marcin; Popadiak Katarzyna; Eick Sigrun; Nguyen Ky-Anh; Riesbeck Kristian; Blom Anna M
Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5537-44.
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2008: Smalley John W; Birss Andrew J; Szmigielski Borys; Potempa Jan
Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis.
Biological chemistry 2008;389(9):1235-8.
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2008: Puklo M; Guentsch A; Hiemstra P S; Eick S; Potempa J
Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteria.
Oral microbiology and immunology 2008;23(4):328-35.
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2008: Dubin Grzegorz; Stec-Niemczyk Justyna; Kisielewska Magdalena; Pustelny Katarzyna; Popowicz Grzegorz M; Bista Michal; Kantyka Tomasz; Boulware Kevin T; Stennicke Henning R; Czarna Anna; Phopaisarn Mullika; Daugherty Patrick S; Thøgersen Ida B; Enghild Jan J; Thornberry Nancy; Dubin Adam; Potempa Jan
Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln.
Journal of molecular biology 2008;379(2):343-56.
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2008: Uehara A; Imamura T; Potempa J; Travis J; Takada H
Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells.
Cellular microbiology 2008;10(5):1181-9.
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2008: Uehara Akiko; Naito Mariko; Imamura Takahisa; Potempa Jan; Travis James; Nakayama Koji; Takada Haruhiko
Dual regulation of interleukin-8 production in human oral epithelial cells upon stimulation with gingipains from Porphyromonas gingivalis.
Journal of medical microbiology 2008;57(Pt 4):500-7.
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2008: Calander Ann-Marie; Dubin Grzegorz; Potempa Jan; Tarkowski Andrej
Staphylococcus aureus infection triggers production of neutralizing, V8 protease-specific antibodies.
FEMS immunology and medical microbiology 2008;52(2):267-72.
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2008: Olczak Teresa; Sroka Aneta; Potempa Jan; Olczak Mariusz
Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization.
Archives of microbiology 2008;189(3):197-210.
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2008: Mallorquí-Fernández Noemí; Manandhar Surya P; Mallorquí-Fernández Goretti; Usón Isabel; Wawrzonek Katarzyna; Kantyka Tomasz; Solà Maria; Thøgersen Ida B; Enghild Jan J; Potempa Jan; Gomis-Rüth F Xavier
A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A.
The Journal of biological chemistry 2008;283(5):2871-82.
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2008: Beaufort Nathalie; Wojciechowski Piotr; Sommerhoff Christian P; Szmyd Grzegorz; Dubin Grzegorz; Eick Sigrun; Kellermann Josef; Schmitt Manfred; Potempa Jan; Magdolen Viktor
The human fibrinolytic system is a target for the staphylococcal metalloprotease aureolysin.
The Biochemical journal 2008;410(1):157-65.
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2008: Guzik Krzysztof; Potempa Jan
Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages.
Biochimie 2008;90(2):405-15.
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2008: Josefsson Elisabet; Kubica Malgorzata; Mydel Piotr; Potempa Jan; Tarkowski Andrej
In vivo sortase A and clumping factor A mRNA expression during Staphylococcus aureus infection.
Microbial pathogenesis 2008;44(2):103-10.
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2008: Shaw Lindsey N; Lindholm Catharina; Prajsnar Tomasz K; Miller Halie K; Brown Melanie C; Golonka Ewa; Stewart George C; Tarkowski Andrej; Potempa Jan
Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses.
PloS one 2008;3(12):e3844.
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2008: Kubica Malgorzata; Guzik Krzysztof; Koziel Joanna; Zarebski Miroslaw; Richter Walter; Gajkowska Barbara; Golda Anna; Maciag-Gudowska Agnieszka; Brix Klaudia; Shaw Les; Foster Timothy; Potempa Jan
A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages.
PloS one 2008;3(1):e1409.
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2007: Kirdis Ebru; Jonsson Ing-Marie; Kubica Malgorzata; Potempa Jan; Josefsson Elisabet; Masalha Mahmud; Foster Simon J; Tarkowski Andrzej
Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis.
Microbial pathogenesis 2007;43(5-6):179-88.
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2007: Smalley John W; Birss Andrew J; Szmigielski Borys; Potempa Jan
Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhaemoglobin.
Archives of biochemistry and biophysics 2007;465(1):44-9.
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2007: Potempa Jan; Nguyen Ky-Anh
Purification and characterization of gingipains.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2007;Chapter 21():Unit 21.20.
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2007: Popadiak Katarzyna; Potempa Jan; Riesbeck Kristian; Blom Anna M
Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7242-50.
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2007: Valnickova Z; Thøgersen I B; Potempa J; Enghild J J
The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal.
Journal of thrombosis and haemostasis : JTH 2007;5(6):1336-7.
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2007: Vincents Bjarne; Onnerfjord Patrik; Gruca Milosz; Potempa Jan; Abrahamson Magnus
Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B.
Biological chemistry 2007;388(4):437-46.
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2007: Kulig Paulina; Zabel Brian A; Dubin Grzegorz; Allen Samantha J; Ohyama Takao; Potempa Jan; Handel Tracy M; Butcher Eugene C; Cichy Joanna
Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3713-20.
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2007: Dubin Grzegorz; Wladyka Benedykt; Stec-Niemczyk Justyna; Chmiel Dorota; Zdzalik Michal; Dubin Adam; Potempa Jan
The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity.
Biological chemistry 2007;388(2):227-35.
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2007: Nguyen Ky-Anh; Travis James; Potempa Jan
Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria?
Journal of bacteriology 2007;189(3):833-43.
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2007: Valnickova Zuzana; Thøgersen Ida B; Potempa Jan; Enghild Jan J
Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase.
The Journal of biological chemistry 2007;282(5):3066-76.
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2007: Guzik K; Bzowska M; Smagur J; Krupa O; Sieprawska M; Travis J; Potempa J
A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages.
Cell death and differentiation 2007;14(1):171-82.
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2006: Sheets Shaun M; Potempa Jan; Travis James; Fletcher Hansel M; Casiano Carlos A
Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis.
Infection and immunity 2006;74(10):5667-78.
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2006: Shaw Lindsey N; Aish Joanne; Davenport Jessica E; Brown Melanie C; Lithgow James K; Simmonite Kay; Crossley Howard; Travis James; Potempa Jan; Foster Simon J
Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus.
Journal of bacteriology 2006;188(17):6070-80.
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2006: Cronan C A; Potempa J; Travis J; Mayo J A
Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II).
Oral microbiology and immunology 2006;21(4):212-7.
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2006: Moon Jonathan L; Shaw Lindsey N; Mayo John A; Potempa Jan; Travis James
Isolation and properties of extracellular proteinases of Penicillium marneffei.
Biological chemistry 2006;387(7):985-93.
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2006: Matheson Nancy R; Potempa Jan; Travis James
Interaction of a novel form of Pseudomonas aeruginosa alkaline protease (aeruginolysin) with interleukin-6 and interleukin-8.
Biological chemistry 2006;387(7):911-5.
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2006: Mydel Piotr; Takahashi Yusuke; Yumoto Hiromichi; Sztukowska Maryta; Kubica Malgorzata; Gibson Frank C; Kurtz Donald M; Travis Jim; Collins L Vincent; Nguyen Ky-Anh; Genco Caroline Attardo; Potempa Jan
Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.
PLoS pathogens 2006;2(7):e76.
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2006: Smalley J W; Birss A J; Szmigielski B; Potempa J
The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IX.
Microbiology (Reading, England) 2006;152(Pt 6):1839-45.
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2006: Matsushita Kenji; Imamura Takahisa; Tancharoen Salunya; Tatsuyama Syouko; Tomikawa Munehiro; Travis James; Potempa Jan; Torii Mitsuo; Maruyama Ikuro
Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a.
Journal of periodontal research 2006;41(3):171-6.
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2006: Popowicz Grzegorz M; Dubin Grzegorz; Stec-Niemczyk Justyna; Czarny Anna; Dubin Adam; Potempa Jan; Holak Tad A
Functional and structural characterization of Spl proteases from Staphylococcus aureus.
Journal of molecular biology 2006;358(1):270-9.
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2006: Bialas Arkadiusz; Grembecka Jolanta; Krowarsch Daniel; Otlewski Jacek; Potempa Jan; Mucha Artur
Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity.
Journal of medicinal chemistry 2006;49(5):1744-53.
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2006: Potempa Jan; Travis J; Golonka E; Shaw Ln
Poison-antidote systems in bacteria: the co-evolution of functional counterparts.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(4):18-22.
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2005: Uehara Akiko; Muramoto Koji; Imamura Takahisa; Nakayama Koji; Potempa Jan; Travis James; Sugawara Shunji; Takada Haruhiko
Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):6076-84.
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2005: Krunkosky Thomas M; Maruo Keishi; Potempa Jan; Jarrett Carla L; Travis James
Inhibition of tumor necrosis factor-alpha-induced RANTES secretion by alkaline protease in A549 cells.
American journal of respiratory cell and molecular biology 2005;33(5):483-9.
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2005: Mezyk-Kopec Renata; Bzowska Malgorzata; Bzowska Monika; Mickowska Barbara; Mak Pawel; Potempa Jan; Bereta Joanna
Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha.
Biological chemistry 2005;386(8):801-11.
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2005: Potempa Jan; Golonka Ewa; Filipek Renata; Shaw Lindsey N
Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases.
Molecular microbiology 2005;57(3):605-10.
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2005: Imamura Takahisa; Tanase Sumio; Szmyd Grzegorz; Kozik Andrzej; Travis James; Potempa Jan
Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus.
The Journal of experimental medicine 2005;201(10):1669-76.
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2005: Tancharoen Salunya; Sarker Krishna Pada; Imamura Takahisa; Biswas Kamal Krishna; Matsushita Kenji; Tatsuyama Shoko; Travis James; Potempa Jan; Torii Mitsuo; Maruyama Ikuro
Neuropeptide release from dental pulp cells by RgpB via proteinase-activated receptor-2 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5796-804.
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2005: Filipek Renata; Potempa Jan; Bochtler Matthias
A comparison of staphostatin B with standard mechanism serine protease inhibitors.
The Journal of biological chemistry 2005;280(15):14669-74.
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2005: Sheets Shaun M; Potempa Jan; Travis James; Casiano Carlos A; Fletcher Hansel M
Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells.
Infection and immunity 2005;73(3):1543-52.
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2005: Mezyk-Kopec Renata; Bzowska Malgorzata; Potempa Jan; Bzowska Monika; Jura Natalia; Sroka Aneta; Black Roy A; Bereta Joanna
Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis.
Infection and immunity 2005;73(3):1506-14.
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2005: Shaw Lindsey N; Golonka Ewa; Szmyd Grzegorz; Foster Simon J; Travis James; Potempa Jan
Cytoplasmic control of premature activation of a secreted protease zymogen: deletion of staphostatin B (SspC) in Staphylococcus aureus 8325-4 yields a profound pleiotropic phenotype.
Journal of bacteriology 2005;187(5):1751-62.
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2005: Kawalec Magdalena; Potempa Jan; Moon Jonathan L; Travis James; Murray Barbara E
Molecular diversity of a putative virulence factor: purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with different enzymatic activities.
Journal of bacteriology 2005;187(1):266-75.
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2005: Potempa Jan; Pike Robert N
Bacterial peptidases.
Contributions to microbiology 2005;12():132-80.
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2004: Sieprawska-Lupa Magdalena; Mydel Piotr; Krawczyk Katarzyna; Wójcik Kinga; Puklo Magdalena; Lupa Boguslaw; Suder Piotr; Silberring Jerzy; Reed Matthew; Pohl Jan; Shafer William; McAleese Fionnuala; Foster Timothy; Travis Jim; Potempa Jan
Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases.
Antimicrobial agents and chemotherapy 2004;48(12):4673-9.
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2004: Sztukowska Maryta; Sroka Aneta; Bugno Marcin; Banbula Agnieszka; Takahashi Yusuke; Pike Robert N; Genco Caroline A; Travis James; Potempa Jan
The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities.
Molecular microbiology 2004;54(5):1393-408.
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2004: Golonka Ewa; Filipek Renata; Sabat Artur; Sinczak Anna; Potempa Jan
Genetic characterization of staphopain genes in Staphylococcus aureus.
Biological chemistry 2004;385(11):1059-67.
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2004: Liu Xinyan; Sroka Aneta; Potempa Jan; Genco Caroline Attardo
Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.
Biological chemistry 2004;385(11):1049-57.
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2004: Imamura Takahisa; Potempa Jan; Travis James
Activation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases.
Biological chemistry 2004;385(11):989-96.
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2004: Filipek Renata; Szczepanowski Roman; Sabat Artur; Potempa Jan; Bochtler Matthias
Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition.
Biochemistry 2004;43(44):14306-15.
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2004: Dubin Grzegorz; Stec-Niemczyk Justyna; Dylag Tomasz; Silberring Jerzy; Dubin Adam; Potempa Jan
Characterisation of a highly specific, endogenous inhibitor of cysteine protease from Staphylococcus epidermidis, a new member of the staphostatin family.
Biological chemistry 2004;385(6):543-6.
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2004: Oleksy Aneta; Golonka Ewa; Banbula Agnieszka; Szmyd Grzegorz; Moon Jonathan; Kubica Malgorzata; Greenbaum Doron; Bogyo Matthew; Foster Timothy J; Travis James; Potempa Jan
Growth phase-dependent production of a cell wall-associated elastinolytic cysteine proteinase by Staphylococcus epidermidis.
Biological chemistry 2004;385(6):525-35.
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2004: Ekici Ozlem Dogan; Götz Marion G; James Karen Ellis; Li Zhao Zhao; Rukamp Brian J; Asgian Juliana L; Caffrey Conor R; Hansell Elizabeth; Dvorák Jan; McKerrow James H; Potempa Jan; Travis James; Mikolajczyk Jowita; Salvesen Guy S; Powers James C
Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases.
Journal of medicinal chemistry 2004;47(8):1889-92.
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2004: García-Castellanos Raquel; Mallorquí-Fernández Goretti; Marrero Aniebrys; Potempa Jan; Coll Miquel; Gomis-Rüth F Xavier
On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator.
The Journal of biological chemistry 2004;279(17):17888-96.
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2004: Dubin Grzegorz; Popowicz Grzegorz; Krajewski Marcin; Potempa Jan; Dubin Adam; Holak Tad A
1H, 15N and 13C NMR resonance assignments of staphostatin A, a specific Staphylococcus aureus cysteine proteinase inhibitor.
Journal of biomolecular NMR 2004;28(3):295-6.
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2004: Shaw Lindsey; Golonka Ewa; Potempa Jan; Foster Simon J
The role and regulation of the extracellular proteases of Staphylococcus aureus.
Microbiology (Reading, England) 2004;150(Pt 1):217-28.
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2003: Imamura Takahisa; Travis James; Potempa Jan
The biphasic virulence activities of gingipains: activation and inactivation of host proteins.
Current protein & peptide science 2003;4(6):443-50.
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2003: Potempa Jan; Sroka Aneta; Imamura Takahisa; Travis James
Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexes.
Current protein & peptide science 2003;4(6):397-407.
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2003: Dubin Grzegorz; Krajewski Marcin; Popowicz Grzegorz; Stec-Niemczyk Justyna; Bochtler Matthias; Potempa Jan; Dubin Adam; Holak Tad A
A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.
Biochemistry 2003;42(46):13449-56.
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2003: Ally Nafisa; Whisstock James C; Sieprawska-Lupa Magdalena; Potempa Jan; Le Bonniec Bernard F; Travis James; Pike Robert N
Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes.
Biochemistry 2003;42(40):11693-700.
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2003: Tada H; Sugawara S; Nemoto E; Imamura T; Potempa J; Travis J; Shimauchi H; Takada H
Proteolysis of ICAM-1 on human oral epithelial cells by gingipains.
Journal of dental research 2003;82(10):796-801.
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2003: Rzychon Malgorzata; Filipek Renata; Sabat Artur; Kosowska Klaudia; Dubin Adam; Potempa Jan; Bochtler Matthias
Staphostatins resemble lipocalins, not cystatins in fold.
Protein science : a publication of the Protein Society 2003;12(10):2252-6.
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2003: García-Castellanos Raquel; Marrero Aniebrys; Mallorquí-Fernández Goretti; Potempa Jan; Coll Miquel; Gomis-Ruth F Xavier
Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance.
The Journal of biological chemistry 2003;278(41):39897-905.
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2003: Filipek Renata; Rzychon Malgorzata; Oleksy Aneta; Gruca Milosz; Dubin Adam; Potempa Jan; Bochtler Matthias
The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease.
The Journal of biological chemistry 2003;278(42):40959-66.
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2003: Rzychon Malgorzata; Sabat Artur; Kosowska Klaudia; Potempa Jan; Dubin Adam
Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases.
Molecular microbiology 2003;49(4):1051-66.
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2003: Dulinski Robert; Suder Piotr; Guevara-Lora Ibeth; Rapala-Kozik Maria; Potempa Jan; Silberring Jerzy; Imamura Takahisa; Travis James; Kozik Andrzej
Attenuated kinin release from human neutrophil elastase-pretreated kininogens by tissue and plasma kallikreins.
Biological chemistry 2003;384(6):929-37.
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2003: Sabat Artur; Krzyszton-Russjan Jolanta; Strzalka Wojciech; Filipek Renata; Kosowska Klaudia; Hryniewicz Waleria; Travis James; Potempa Jan
New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates.
Journal of clinical microbiology 2003;41(4):1801-4.
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2003: Mikolajczyk Jowita; Boatright Kelly M; Stennicke Henning R; Nazif Tamim; Potempa Jan; Bogyo Matthew; Salvesen Guy S
Sequential autolytic processing activates the zymogen of Arg-gingipain.
The Journal of biological chemistry 2003;278(12):10458-64.
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2002: Cichy Joanna; Bals Robert; Potempa Jan; Mani Anne; Puré Ellen
Proteinase-mediated release of epithelial cell-associated CD44. Extracellular CD44 complexes with components of cellular matrices.
The Journal of biological chemistry 2002;277(46):44440-7.
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2002: Krauser Joel A; Potempa Jan; Travis James; Powers James C
Inhibition of arginine gingipains (RgpB and HRgpA) with benzamidine inhibitors: zinc increases inhibitory potency.
Biological chemistry 2002;383(7-8):1193-8.
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2002: Imamura Takahisa; Tanase Sumio; Hayashi Izumi; Potempa Jan; Kozik Andrzej; Travis James
Release of a new vascular permeability enhancing peptide from kininogens by human neutrophil elastase.
Biochemical and biophysical research communications 2002;294(2):423-8.
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2002: Tada Hiroyuki; Sugawara Shunji; Nemoto Eiji; Takahashi Nobuhiro; Imamura Takahisa; Potempa Jan; Travis James; Shimauchi Hidetoshi; Takada Haruhiko
Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production.
Infection and immunity 2002;70(6):3304-7.
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2002: Katz Jannet; Yang Qiu-Bo; Zhang Ping; Potempa Jan; Travis James; Michalek Suzanne M; Balkovetz Daniel F
Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains.
Infection and immunity 2002;70(5):2512-8.
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2002: Oleksy Aneta; Banbula Agnieszka; Bugno Marcin; Travis James; Potempa Jan
Proteolysis of interleukin-6 receptor (IL-6R) by Porphyromonas gingivalis cysteine proteinases (gingipains) inhibits interleukin-6-mediated cell activation.
Microbial pathogenesis 2002;32(4):173-81.
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2002: Sztukowska Maryta; Bugno Marcin; Potempa Jan; Travis James; Kurtz Donald M
Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis.
Molecular microbiology 2002;44(2):479-88.
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2002: Kosowska Klaudia; Reinholdt Jesper; Rasmussen Lone Kjar; Sabat Artur; Potempa Jan; Kilian Mogens; Poulsen Knud
The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase.
The Journal of biological chemistry 2002;277(14):11987-94.
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2001: Imamura T; Matsushita K; Travis J; Potempa J
Inhibition of trypsin-like cysteine proteinases (gingipains) from Porphyromonas gingivalis by tetracycline and its analogues.
Antimicrobial agents and chemotherapy 2001;45(10):2871-6.
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2001: Sroka A; Sztukowska M; Potempa J; Travis J; Genco C A
Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.
Journal of bacteriology 2001;183(19):5609-16.
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2001: Banbula A; Mak P; Smoluch M; Travis J; Potempa J
Arginine-specific cysteine proteinase from porphyromonas gingivalis as a convenient tool in protein chemistry.
Biological chemistry 2001;382(9):1399-404.
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2001: Lourbakos A; Potempa J; Travis J; D'Andrea M R; Andrade-Gordon P; Santulli R; Mackie E J; Pike R N
Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion.
Infection and immunity 2001;69(8):5121-30.
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2001: Nakagawa T; Sims T; Fan Q; Potempa J; Travis J; Houston L; Page R C
Functional characteristics of antibodies induced by Arg-gingipain (HRgpA) and Lys-gingipain (Kgp) from Porphyromonas gingivalis.
Oral microbiology and immunology 2001;16(4):202-11.
-
2001: McAleese F M; Walsh E J; Sieprawska M; Potempa J; Foster T J
Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease.
The Journal of biological chemistry 2001;276(32):29969-78.
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2001: Snipas S J; Stennicke H R; Riedl S; Potempa J; Travis J; Barrett A J; Salvesen G S
Inhibition of distant caspase homologues by natural caspase inhibitors.
The Biochemical journal 2001;357(Pt 2):575-80.
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2001: Lourbakos A; Yuan Y P; Jenkins A L; Travis J; Andrade-Gordon P; Santulli R; Potempa J; Pike R N
Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity.
Blood 2001;97(12):3790-7.
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2001: Imamura T; Banbula A; Pereira P J; Travis J; Potempa J
Activation of human prothrombin by arginine-specific cysteine proteinases (Gingipains R) from porphyromonas gingivalis.
The Journal of biological chemistry 2001;276(22):18984-91.
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2001: Gusman H; Travis J; Helmerhorst E J; Potempa J; Troxler R F; Oppenheim F G
Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontal disease.
Infection and immunity 2001;69(3):1402-8.
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2001: Banbula A; Yen J; Oleksy A; Mak P; Bugno M; Travis J; Potempa J
Porphyromonas gingivalis DPP-7 represents a novel type of dipeptidylpeptidase.
The Journal of biological chemistry 2001;276(9):6299-305.
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2001: Rubinstein I; Potempa J; Travis J; Gao X P
Mechanisms mediating Porphyromonas gingivalis gingipain RgpA-induced oral mucosa inflammation in vivo.
Infection and immunity 2001;69(2):1199-201.
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2001: Nelson D; Goldstein J M; Boatright K; Harty D W; Cook S L; Hickman P J; Potempa J; Travis J; Mayo J A
pH-regulated secretion of a glyceraldehyde-3-phosphate dehydrogenase from Streptococcus gordonii FSS2: purification, characterization, and cloning of the gene encoding this enzyme.
Journal of dental research 2001;80(1):371-7.
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2001: Imamura T; Tanase S; Hamamoto T; Potempa J; Travis J
Activation of blood coagulation factor IX by gingipains R, arginine-specific cysteine proteinases from Porphyromonas gingivalis.
The Biochemical journal 2001;353(Pt 2):325-31.
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2000: Potempa J; Banbula A; Travis J
Role of bacterial proteinases in matrix destruction and modulation of host responses.
Periodontology 2000 2000;24():153-92.
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2000: Imamura T; Potempa J; Travis J
Comparison of pathogenic properties between two types of arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis.
Microbial pathogenesis 2000;29(3):155-63.
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2000: Travis J; Potempa J
Bacterial proteinases as targets for the development of second-generation antibiotics.
Biochimica et biophysica acta 2000;1477(1-2):35-50.
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2000: Banbula A; Bugno M; Goldstein J; Yen J; Nelson D; Travis J; Potempa J
Emerging family of proline-specific peptidases of Porphyromonas gingivalis: purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV.
Infection and immunity 2000;68(3):1176-82.
-
2000: Abaibou H; Ma Q; Olango G J; Potempa J; Travis J; Fletcher H M
Unaltered expression of the major protease genes in a non-virulent recA-defective mutant of Porphyromonas gingivalis W83.
Oral microbiology and immunology 2000;15(1):40-7.
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2000: Sabat A; Kosowska K; Poulsen K; Kasprowicz A; Sekowska A; van Den Burg B; Travis J; Potempa J
Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus.
Infection and immunity 2000;68(2):973-6.
-
2000: Travis J; Banbula A; Potempa J
The role of bacterial and host proteinases in periodontal disease.
Advances in experimental medicine and biology 2000;477():455-65.
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1999: Curtis M A; Kuramitsu H K; Lantz M; Macrina F L; Nakayama K; Potempa J; Reynolds E C; Aduse-Opoku J
Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis.
Journal of periodontal research 1999;34(8):464-72.
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1999: Rapala-Kozik M; Potempa J; Nelson D; Kozik A; Travis J
Comparative cleavage sites within the reactive-site loop of native and oxidized alpha1-proteinase inhibitor by selected bacterial proteinases.
Biological chemistry 1999;380(10):1211-6.
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1999: Eichinger A; Beisel H G; Jacob U; Huber R; Medrano F J; Banbula A; Potempa J; Travis J; Bode W
Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold.
The EMBO journal 1999;18(20):5453-62.
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1999: Simpson W; Wang C Y; Mikolajczyk-Pawlinska J; Potempa J; Travis J; Bond V C; Genco C A
Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis.
Infection and immunity 1999;67(10):5012-20.
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1999: Banbula A; Bugno M; Kuster A; Heinrich P C; Travis J; Potempa J
Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis.
Biochemical and biophysical research communications 1999;261(3):598-602.
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1999: McGraw W T; Potempa J; Farley D; Travis J
Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase.
Infection and immunity 1999;67(7):3248-56.
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1999: Janusz M J; Hare M; Durham S L; Potempa J; McGraw W; Pike R; Travis J; Shapiro S D
Cartilage proteoglycan degradation by a mouse transformed macrophage cell line is mediated by macrophage metalloelastase.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(5):280-8.
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1999: Nelson D; Potempa J; Kordula T; Travis J
Purification and characterization of a novel cysteine proteinase (periodontain) from Porphyromonas gingivalis. Evidence for a role in the inactivation of human alpha1-proteinase inhibitor.
The Journal of biological chemistry 1999;274(18):12245-51.
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1999: Banbula A; Mak P; Bugno M; Silberring J; Dubin A; Nelson D; Travis J; Potempa J
Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis.
The Journal of biological chemistry 1999;274(14):9246-52.
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1999: Genco C A; Potempa J; Mikolajczyk-Pawlinska J; Travis J
Role of gingipains R in the pathogenesis of Porphyromonas gingivalis-mediated periodontal disease.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;28(3):456-65.
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1999: Hosotaki K; Imamura T; Potempa J; Kitamura N; Travis J
Activation of protein C by arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis.
Biological chemistry 1999;380(1):75-80.
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1998: Mikolajczyk-Pawlinska J; Travis J; Potempa J
Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease.
FEBS letters 1998;440(3):282-6.
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1998: Kozik A; Moore R B; Potempa J; Imamura T; Rapala-Kozik M; Travis J
A novel mechanism for bradykinin production at inflammatory sites. Diverse effects of a mixture of neutrophil elastase and mast cell tryptase versus tissue and plasma kallikreins on native and oxidized kininogens.
The Journal of biological chemistry 1998;273(50):33224-9.
-
1998: Lourbakos A; Chinni C; Thompson P; Potempa J; Travis J; Mackie E J; Pike R N
Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis.
FEBS letters 1998;435(1):45-8.
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1998: Banbula A; Potempa J; Travis J; Fernandez-Catalán C; Mann K; Huber R; Bode W; Medrano F
Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution.
Structure (London, England : 1993) 1998;6(9):1185-93.
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1998: Genco C A; Odusanya B M; Potempa J; Mikolajczyk-Pawlinska J; Travis J
A peptide domain on gingipain R which confers immunity against Porphyromonas gingivalis infection in mice.
Infection and immunity 1998;66(9):4108-14.
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1998: Potempa J; Mikolajczyk-Pawlinska J; Brassell D; Nelson D; Thøgersen I B; Enghild J J; Travis J
Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis.
The Journal of biological chemistry 1998;273(34):21648-57.
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1998: Mailhot J M; Potempa J; Stein S H; Travis J; Sterrett J D; Hanes P J; Russell C M
A relationship between proteinase activity and clinical parameters in the treatment of periodontal disease.
Journal of clinical periodontology 1998;25(7):578-84.
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1998: Nelson D; Potempa J; Travis J
Inactivation of alpha1-proteinase inhibitor as a broad screen for detecting proteolytic activities in unknown samples.
Analytical biochemistry 1998;260(2):230-6.
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1998: Kozik A; Potempa J; Travis J
Spontaneous inactivation of human lung tryptase as probed by size-exclusion chromatography and chemical cross-linking: dissociation of active tetrameric enzyme into inactive monomers is the primary event of the entire process.
Biochimica et biophysica acta 1998;1385(1):139-48.
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1998: Banbula A; Potempa J; Travis J; Bode W; Medrano F J
Crystallization and preliminary X-ray diffraction analysis of gingipain R2 from Porphyromonas gingivalis in complex with H-D-Phe-Phe-Arg-chloromethylketone.
Protein science : a publication of the Protein Society 1998;7(5):1259-61.
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1998: Calkins C C; Platt K; Potempa J; Travis J
Inactivation of tumor necrosis factor-alpha by proteinases (gingipains) from the periodontal pathogen, Porphyromonas gingivalis. Implications of immune evasion.
The Journal of biological chemistry 1998;273(12):6611-4.
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1998: Bagarozzi D A; Potempa J; Travis J
Purification and characterization of an arginine-specific peptidase from ragweed (Ambrosia artemisiifolia) pollen.
American journal of respiratory cell and molecular biology 1998;18(3):363-9.
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1998: Mikolajczyk-Pawlinska J; Kordula T; Pavloff N; Pemberton P A; Chen W C; Travis J; Potempa J
Genetic variation of Porphyromonas gingivalis genes encoding gingipains, cysteine proteinases with arginine or lysine specificity.
Biological chemistry 1998;379(2):205-11.
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1997: Cichy J; Rose-John S; Potempa J; Pryjma J; Travis J
Oncostatin M stimulates the expression and release of the IL-6 receptor in human hepatoma HepG2 cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5648-53.
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1997: Abrahamson M; Wikström M; Potempa J; Renvert S; Hall A
Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis.
Molecular pathology : MP 1997;50(6):291-7.
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1997: Pike R N; Potempa J; Skinner R; Fitton H L; McGraw W T; Travis J; Owen M; Jin L; Carrell R W
Heparin-dependent modification of the reactive center arginine of antithrombin and consequent increase in heparin binding affinity.
The Journal of biological chemistry 1997;272(32):19652-5.
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1997: Imamura T; Potempa J; Tanase S; Travis J
Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis.
The Journal of biological chemistry 1997;272(25):16062-7.
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1997: Potempa J; Pike R; Travis J
Titration and mapping of the active site of cysteine proteinases from Porphyromonas gingivalis (gingipains) using peptidyl chloromethanes.
Biological chemistry 1997;378(3-4):223-30.
-
1997: Cichy J; Potempa J; Travis J
Biosynthesis of alpha1-proteinase inhibitor by human lung-derived epithelial cells.
The Journal of biological chemistry 1997;272(13):8250-5.
-
1997: Grøn H; Pike R; Potempa J; Travis J; Thøgersen I B; Enghild J J; Pizzo S V
The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis.
Journal of periodontal research 1997;32(1 Pt 1):61-8.
-
1997: Travis J; Pike R; Imamura T; Potempa J
Porphyromonas gingivalis proteinases as virulence factors in the development of periodontitis.
Journal of periodontal research 1997;32(1 Pt 2):120-5.
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1997: Pavloff N; Pemberton P A; Potempa J; Chen W C; Pike R N; Prochazka V; Kiefer M C; Travis J; Barr P J
Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinases.
The Journal of biological chemistry 1997;272(3):1595-600.
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1996: Koloczek H; Banbula A; Salvesen G S; Potempa J
Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy.
Protein science : a publication of the Protein Society 1996;5(11):2226-35.
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1996: Hof P; Mayr I; Huber R; Korzus E; Potempa J; Travis J; Powers J C; Bode W
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.
The EMBO journal 1996;15(20):5481-91.
-
1996: Bagarozzi D A; Pike R; Potempa J; Travis J
Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen.
The Journal of biological chemistry 1996;271(42):26227-32.
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1996: Jagels M A; Travis J; Potempa J; Pike R; Hugli T E
Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis.
Infection and immunity 1996;64(6):1984-91.
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1996: Pike R N; Potempa J; McGraw W; Coetzer T H; Travis J
Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis.
Journal of bacteriology 1996;178(10):2876-82.
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1996: Discipio R G; Daffern P J; Kawahara M; Pike R; Travis J; Hugli T E; Potempa J
Cleavage of human complement component C5 by cysteine proteinases from Porphyromonas (Bacteroides) gingivalis. Prior oxidation of C5 augments proteinase digestion of C5.
Immunology 1996;87(4):660-7.
-
1996: Potempa J; Travis J
Porphyromonas gingivalis proteinases in periodontitis, a review.
Acta biochimica Polonica 1996;43(3):455-65.
-
1996: Jagels M A; Ember J A; Travis J; Potempa J; Pike R; Hugli T E
Cleavage of the human C5A receptor by proteinases derived from Porphyromonas gingivalis: cleavage of leukocyte C5a receptor.
Advances in experimental medicine and biology 1996;389():155-64.
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1995: Imamura T; Potempa J; Pike R N; Moore J N; Barton M H; Travis J
Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites.
Infection and immunity 1995;63(12):4877-82.
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1995: Potempa J; Pavloff N; Travis J
Porphyromonas gingivalis: a proteinase/gene accounting audit.
Trends in microbiology 1995;3(11):430-4.
-
1995: Travis J; Potempa J; Maeda H
Are bacterial proteinases pathogenic factors?
Trends in microbiology 1995;3(10):405-7.
-
1995: Cichy J; Potempa J; Chawla R K; Travis J
Stimulatory effect of inflammatory cytokines on alpha 1-antichymotrypsin expression in human lung-derived epithelial cells.
The Journal of clinical investigation 1995;95(6):2729-33.
-
1995: Imamura T; Potempa J; Pike R N; Travis J
Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis.
Infection and immunity 1995;63(5):1999-2003.
-
1995: Potempa J; Pike R; Travis J
The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain.
Infection and immunity 1995;63(4):1176-82.
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1995: Cichy J; Potempa J; Travis J
Effect of dexamethasone on alpha 1-proteinase inhibitor synthesis in human cells of monocytic origin.
Biochemical and biophysical research communications 1995;208(1):216-22.
-
1995: Cichy J; Potempa J; Chawla R K; Travis J
Regulation of alpha 1-antichymotrypsin synthesis in cells of epithelial origin.
FEBS letters 1995;359(2-3):262-6.
-
1995: Potempa J; Enghild J J; Travis J
The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin.
The Biochemical journal 1995;306 ( Pt 1)():191-7.
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1995: Pavloff N; Potempa J; Pike R N; Prochazka V; Kiefer M C; Travis J; Barr P J
Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyprotein.
The Journal of biological chemistry 1995;270(3):1007-10.
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1995: Prokesová L; Potuzníkovà B; Potempa J; Zikán J; Radl J; Porwit-Bóbr Z; John C
Cleavage of human immunoglobulins by proteinase from Staphylococcus aureus.
Advances in experimental medicine and biology 1995;371A():613-6.
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1994: Travis J; Pike R; Imamura T; Potempa J
The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease.
American journal of respiratory and critical care medicine 1994;150(6 Pt 2):S143-6.
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1994: Imamura T; Pike R N; Potempa J; Travis J
Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway.
The Journal of clinical investigation 1994;94(1):361-7.
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1994: Potempa J; Korzus E; Travis J
The serpin superfamily of proteinase inhibitors: structure, function, and regulation.
The Journal of biological chemistry 1994;269(23):15957-60.
-
1994: Dubin A; Potempa J; Travis J
Structural and functional characterization of elastases from horse neutrophils.
The Biochemical journal 1994;300 ( Pt 2)():401-6.
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1994: Koj A; Guzdek A; Potempa J; Korzus E; Travis J
Origin of circulating acute phase cytokines: modified proteins may trigger IL-6 production by macrophages. Preliminary report.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1994;45(1):69-80.
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1994: Pike R; McGraw W; Potempa J; Travis J
Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins.
The Journal of biological chemistry 1994;269(1):406-11.
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1994: Wikström M; Potempa J; Polanowski A; Travis J; Renvert S
Detection of Porphyromonas gingivalis in gingival exudate by a dipeptide-enhanced trypsin-like activity.
Journal of periodontology 1994;65(1):47-55.
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1992: Wingrove J A; DiScipio R G; Chen Z; Potempa J; Travis J; Hugli T E
Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis.
The Journal of biological chemistry 1992;267(26):18902-7.
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1992: Chen Z; Potempa J; Polanowski A; Wikstrom M; Travis J
Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis.
The Journal of biological chemistry 1992;267(26):18896-901.
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1992: Baumann U; Bode W; Huber R; Travis J; Potempa J
Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution.
Journal of molecular biology 1992;226(4):1207-18.
-
1992: Dubin A; Travis J; Enghild J J; Potempa J
Equine leukocyte elastase inhibitor. Primary structure and identification as a thymosin-binding protein.
The Journal of biological chemistry 1992;267(10):6576-83.
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1992: Prokesová L; Potuzníková B; Potempa J; Zikán J; Radl J; Hachová L; Baran K; Porwit-Bobr Z; John C
Cleavage of human immunoglobulins by serine proteinase from Staphylococcus aureus.
Immunology letters 1992;31(3):259-65.
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1991: Potempa J; Fedak D; Dubin A; Mast A; Travis J
Proteolytic inactivation of alpha-1-anti-chymotrypsin. Sites of cleavage and generation of chemotactic activity.
The Journal of biological chemistry 1991;266(32):21482-7.
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1991: Chen Z X; Potempa J; Polanowski A; Renvert S; Wikström M; Travis J
Stimulation of proteinase and amidase activities in Porphyromonas (Bacteroides) gingivalis by amino acids and dipeptides.
Infection and immunity 1991;59(8):2846-50.
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1991: Darien B J; Potempa J; Moore J N; Travis J
Antithrombin III activity in horses with colic: an analysis of 46 cases.
Equine veterinary journal 1991;23(3):211-4.
-
1991: Koloczek H; Wasniowska A; Potempa J; Wasylewski Z
The fluorescence quenching resolved spectra and red-edge excitation fluorescence measurements of human alpha 1-proteinase inhibitor.
Biochimica et biophysica acta 1991;1073(3):619-25.
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1991: Prokesová L; Porwit-Bóbr Z; Baran K; Potempa J; Pospísil M; John C
Effect of metalloproteinase from Staphylococcus aureus on in vitro stimulation of human lymphocytes.
Immunology letters 1991;27(3):225-30.
-
1991: Potempa J; Wunderlich J K; Travis J
Comparative properties of three functionally different but structurally related serpin variants from horse plasma.
The Biochemical journal 1991;274 ( Pt 2)():465-71.
-
1991: Travis J; Dubin A; Potempa J; Watorek W; Kurdowska A
Neutrophil proteinases. Caution signs in designing inhibitors against enzymes with possible multiple functions.
Annals of the New York Academy of Sciences 1991;624():81-6.
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1991: Korzus E; Dubin A; Potempa J; Travis J
Elastase inhibitor from mammalian neutrophil cytosol.
Biomedica biochimica acta 1991;50(4-6):687-90.
-
1990: Guzdek A; Potempa J; Dubin A; Travis J
Comparative properties of human alpha-1-proteinase inhibitor glycosylation variants.
FEBS letters 1990;272(1-2):125-7.
-
1990: Travis J; Guzdek A; Potempa J; Watorek W
Serpins: structure and mechanism of action.
Biological chemistry Hoppe-Seyler 1990;371 Suppl():3-11.
-
1990: Dubin A; Potempa J; Travis J
Isolation of nine human plasma proteinase inhibitors by sequential affinity chromatography.
Preparative biochemistry 1990;20(1):63-74.
-
1989: Potempa J; Porwit-Bobr Z; Travis J
Stabilization vs. degradation of Staphylococcus aureus metalloproteinase.
Biochimica et biophysica acta 1989;993(2-3):301-4.
-
1989: Baran K; Górka M; Potempa J; Porwit-Bóbr Z
Chemoattractant activity of Staphylococcus aureus serine proteinase modified human plasma alpha-1-proteinase inhibitor.
Antonie van Leeuwenhoek 1989;56(4):361-5.
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1989: Potempa J; Kwon K; Chawla R; Travis J
Inter-alpha-trypsin inhibitor. Inhibition spectrum of native and derived forms.
The Journal of biological chemistry 1989;264(25):15109-14.
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1989: Shieh B H; Potempa J; Travis J
The use of alpha 2-antiplasmin as a model for the demonstration of complex reversibility in serpins.
The Journal of biological chemistry 1989;264(23):13420-3.
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1989: Porwit-Bobr Z; Ochalek T; Prokesova L; John C; Baran K; Potempa J
Effects of serine proteinase from Staphylococcus aureus V8 cells on Con A stimulation of human lymphocytes.
Microbiologica 1989;12(2):139-42.
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1989: Darien B J; Potempa J; Moore J N; Travis J
Antithrombin III activity (residual thrombin activity) in plasma from non-medicated or heparinized horses.
Veterinary research communications 1989;13(1):31-46.
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1988: Travis J; Shieh B H; Potempa J
The functional role of acute phase plasma proteinase inhibitors.
The Tokai journal of experimental and clinical medicine 1988;13(6):313-20.
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1988: Prokesová L; Porwit-Bóbr Z; Baran K; Potempa J; John C
Effect of serine proteinase from Staphylococcus aureus on in vitro stimulation of human lymphocytes.
Immunology letters 1988;19(2):127-32.
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1988: Potempa J; Shieh B H; Travis J
Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites.
Science (New York, N.Y.) 1988;241(4866):699-700.
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1988: Potempa J; Dubin A; Watorek W; Travis J
An elastase inhibitor from equine leukocyte cytosol belongs to the serpin superfamily. Further characterization and amino acid sequence of the reactive center.
The Journal of biological chemistry 1988;263(15):7364-9.
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1988: Potempa J; Dubin A; Korzus G; Travis J
Degradation of elastin by a cysteine proteinase from Staphylococcus aureus.
The Journal of biological chemistry 1988;263(6):2664-7.
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1988: Potempa J; Korzus E; Silberring J; Dubin A
Noncatalytic protein component of elastase from horse leucocytes. A protein with regulatory function.
The International journal of biochemistry 1988;20(1):105-8.
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1986: Potempa J; Watorek W; Travis J
The inactivation of human plasma alpha 1-proteinase inhibitor by proteinases from Staphylococcus aureus.
The Journal of biological chemistry 1986;261(30):14330-4.
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1986: Wasylewski Z; Stryjewski W; Wasniowska A; Potempa J; Baran K
Effect of calcium binding on conformational changes of staphylococcal metalloproteinase measured by means of intrinsic protein fluorescence.
Biochimica et biophysica acta 1986;871(2):177-81.
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1986: Dubin A; Potempa J; Schnebli H P; Koj A
Comparison of specificity of human and horse leucocyte proteinases with synthetic peptide substrates.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1986;24(2):157-61.
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1986: Potempa J; Korzus E; Dubin A; Silberring J
Elastinolytic activity of horse leukocyte proteinases. Comparison with elastases from human leukocytes and porcine pancreas.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1986;24(2):149-56.
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1986: Dubin A; Potempa J; Turyna B
The interaction between some serine proteinases and horse leucocyte inhibitor.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1986;24(2):163-8.
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1986: Dubin A; Potempa J; Kurdowska A; Pajdak W; Koj A
Comparison of antiproteolytic activities of alpha-1-proteinase inhibitors from the plasma of some mammalian species.
Comparative biochemistry and physiology. B, Comparative biochemistry 1986;83(2):375-80.
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1985: Potempa J; Dubin A; Seemüller U; Schnebli H P; Koj A
Inhibition of horse leucocyte proteinases by eglin, a proteinase inhibitor from leeches.
Biomedica biochimica acta 1985;44(2):335-9.
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1985: Potempa J; Dubin A
[Evolution of the structure and function of serine proteolytic enzymes]
Postepy biochemii 1985;31(3-4):531-54.
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1985: Dubin A; Potempa J; Silberring J
Horse leucocyte proteinase-inhibitor system. Kinetic parameters of the inhibition reaction.
The International journal of biochemistry 1985;17(4):509-13.
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1984: Dubin A; Potempa J; Silberring J
Alpha 2-macroglobulin from horse plasma. Purification, properties and interaction with certain serine proteinases.
Biochemistry international 1984;8(4):589-96.
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1982: Potempa J
Cibacron Blue-induced modification of neutral proteinase from horse blood leukocytes.
Acta biologica et medica Germanica 1982;41(1):47-52.
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1982: Potempa J
Isolation and properties of an elastase-like proteinase from horse blood leucocytes.
Folia histochemica et cytochemica 1982;20(1-2):41-52.
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