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Gerhard Wagner

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Procedures

Chemicals & Drugs

Physiology

Protein Folding

Living Beings

Escherichia coli

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Co-Publications
Name
23
Sun, Zhen-Yu
21
Reinherz, Ellis
15
Marintchev, Assen
13
Frueh, Dominique
11
Wüthrich, Kurt
10
Dötsch, Volker
10
Arthanari, Haribabu
9
Gross, John
9
Matsuo, H
9
Lugovskoy, Alexey
9
Hoch, Jeffrey
9
Hyberts, Sven
9
Verdine, Gregory
8
Walsh, Christopher
7
Yuan, Junying

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Publications

TOP 3
Frueh Dominique P; Leed Alison; Arthanari Haribabu; Koglin Alexander; Walsh Christopher T; Wagner Gerhard
Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in (15)N-(13)C-ILV methyl labeled proteins.
Hyberts Sven G; Frueh Dominique P; Arthanari Haribabu; Wagner Gerhard
FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation.
Hiller Sebastian; Ibraghimov Ilghis; Wagner Gerhard; Orekhov Vladislav Y
Coupled decomposition of four-dimensional NOESY spectra.

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All Publications

2009: Frueh Dominique P; Leed Alison; Arthanari Haribabu; Koglin Alexander; Walsh Christopher T; Wagner Gerhard
Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in (15)N-(13)C-ILV methyl labeled proteins.
Journal of biomolecular NMR 2009;45(3):311-8.
2009: Hyberts Sven G; Frueh Dominique P; Arthanari Haribabu; Wagner Gerhard
FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation.
Journal of biomolecular NMR 2009;45(3):283-94.
2009: Hiller Sebastian; Ibraghimov Ilghis; Wagner Gerhard; Orekhov Vladislav Y
Coupled decomposition of four-dimensional NOESY spectra.
Journal of the American Chemical Society 2009;131(36):12970-8.
2009: Frueh Dominique P; Arthanari Haribabu; Koglin Alexander; Walsh Christopher T; Wagner Gerhard
A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins.
Journal of the American Chemical Society 2009;131(36):12880-1.
2009: Hiller Sebastian; Wagner Gerhard
The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins.
Current opinion in structural biology 2009;19(4):396-401.
2009: Yu Yingpu; Marintchev Assen; Kolupaeva Victoria G; Unbehaun Anett; Veryasova Tatyana; Lai Shao-Chiang; Hong Peng; Wagner Gerhard; Hellen Christopher U T; Pestova Tatyana V
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.
Nucleic acids research 2009;37(15):5167-82.
2009: Song Likai; Sun Zhen-Yu J; Coleman Kate E; Zwick Michael B; Gach Johannes S; Wang Jia-huai; Reinherz Ellis L; Wagner Gerhard; Kim Mikyung
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):9057-62.
2009: Hiller Sebastian; Arthanari Haribabu; Wagner Gerhard
The T-lock: automated compensation of radio-frequency induced sample heating.
Journal of biomolecular NMR 2009;44(2):69-76.
2009: Hemond Michael; Rothstein Thomas L; Wagner Gerhard
Fas apoptosis inhibitory molecule contains a novel beta-sandwich in contact with a partially ordered domain.
Journal of molecular biology 2009;386(4):1024-37.
2009: Marintchev Assen; Edmonds Katherine A; Marintcheva Boriana; Hendrickson Elthea; Oberer Monika; Suzuki Chikako; Herdy Barbara; Sonenberg Nahum; Wagner Gerhard
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation.
Cell 2009;136(3):447-60.
2009: Thakur Jitendra K; Arthanari Haribabu; Yang Fajun; Chau Katherine H; Wagner Gerhard; Näär Anders M
Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p.
The Journal of biological chemistry 2009;284(7):4422-8.
2008: Hiller Sebastian; Garces Robert G; Malia Thomas J; Orekhov Vladislav Y; Colombini Marco; Wagner Gerhard
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
Science (New York, N.Y.) 2008;321(5893):1206-10.
2008: Koglin Alexander; Löhr Frank; Bernhard Frank; Rogov Vladimir V; Frueh Dominique P; Strieter Eric R; Mofid Mohammad R; Güntert Peter; Wagner Gerhard; Walsh Christopher T; Marahiel Mohamed A; Dötsch Volker
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase.
Nature 2008;454(7206):907-11.
2008: Frueh Dominique P; Arthanari Haribabu; Koglin Alexander; Vosburg David A; Bennett Andrew E; Walsh Christopher T; Wagner Gerhard
Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase.
Nature 2008;454(7206):903-6.
2008: Takeuchi Koh; Yang Hailin; Ng Elise; Park Sungh-youk; Sun Zhen-Yu J; Reinherz Ellis L; Wagner Gerhard
Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
Journal of molecular biology 2008;380(4):704-16.
2008: Arthanari H; Frueh D; Wagner G; Pryor B; Khaneja N
Fourier synthesis techniques for NMR spectroscopy in inhomogeneous fields.
The Journal of chemical physics 2008;128(21):214503.
2008: Degterev Alexei; Hitomi Junichi; Germscheid Megan; Ch'en Irene L; Korkina Olga; Teng Xin; Abbott Derek; Cuny Gregory D; Yuan Chengye; Wagner Gerhard; Hedrick Stephen M; Gerber Scott A; Lugovskoy Alexey; Yuan Junying
Identification of RIP1 kinase as a specific cellular target of necrostatins.
Nature chemical biology 2008;4(5):313-21.
2008: Thakur Jitendra K; Arthanari Haribabu; Yang Fajun; Pan Shih-Jung; Fan Xiaochun; Breger Julia; Frueh Dominique P; Gulshan Kailash; Li Darrick K; Mylonakis Eleftherios; Struhl Kevin; Moye-Rowley W Scott; Cormack Brendan P; Wagner Gerhard; Näär Anders M
A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Nature 2008;452(7187):604-9.
2008: Selenko Philipp; Frueh Dominique P; Elsaesser Simon J; Haas Wilhelm; Gygi Steven P; Wagner Gerhard
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy.
Nature structural & molecular biology 2008;15(3):321-9.
2008: Suzuki Chikako; Garces Robert G; Edmonds Katherine A; Hiller Sebastian; Hyberts Sven G; Marintchev Assen; Wagner Gerhard
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3274-9.
2008: Marintcheva Boriana; Marintchev Assen; Wagner Gerhard; Richardson Charles C
Acidic C-terminal tail of the ssDNA-binding protein of bacteriophage T7 and ssDNA compete for the same binding surface.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):1855-60.
2008: Sun Zhen-Yu J; Oh Kyoung Joon; Kim Mikyung; Yu Jessica; Brusic Vladimir; Song Likai; Qiao Zhisong; Wang Jia-huai; Wagner Gerhard; Reinherz Ellis L
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane.
Immunity 2008;28(1):52-63.
2008: Reibarkh Mikhail; Yamamoto Yasufumi; Singh Chingakham Ranjit; del Rio Federico; Fahmy Amr; Lee Bumjun; Luna Rafael E; Ii Miki; Wagner Gerhard; Asano Katsura
Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection.
The Journal of biological chemistry 2008;283(2):1094-103.
2008: Lindqvist Lisa; Oberer Monika; Reibarkh Mikhail; Cencic Regina; Bordeleau Marie-Eve; Vogt Emily; Marintchev Assen; Tanaka Junichi; Fagotto Francois; Altmann Michael; Wagner Gerhard; Pelletier Jerry
Selective pharmacological targeting of a DEAD box RNA helicase.
PloS one 2008;3(2):e1583.
2007: Tsodikov Oleg V; Ivanov Dmitri; Orelli Barbara; Staresincic Lidija; Shoshani Ilana; Oberman Robert; Schärer Orlando D; Wagner Gerhard; Ellenberger Tom
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.
The EMBO journal 2007;26(22):4768-76.
2007: Zhong Weimin; Dixit Surjit B; Mallis Robert J; Arthanari Haribabu; Lugovskoy Alexey A; Beveridge David L; Wagner Gerhard; Reinherz Ellis L
CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vbeta but diverse Valpha repertoire: functional and structural implications.
Journal of molecular biology 2007;372(2):535-48.
2007: Catic André; Sun Zhen-Yu J; Ratner Daniel M; Misaghi Shahram; Spooner Eric; Samuelson John; Wagner Gerhard; Ploegh Hidde L
Sequence and structure evolved separately in a ribosomal ubiquitin variant.
The EMBO journal 2007;26(14):3474-83.
2007: Unbehaun Anett; Marintchev Assen; Lomakin Ivan B; Didenko Tatyana; Wagner Gerhard; Hellen Christopher U T; Pestova Tatyana V
Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing.
The EMBO journal 2007;26(13):3109-23.
2007: Léjard Véronique; Brideau Gaëlle; Blais Frédéric; Salingcarnboriboon Ruchanee; Wagner Gerhard; Roehrl Michael H A; Noda Masaki; Duprez Delphine; Houillier Pascal; Rossert Jerome
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.
The Journal of biological chemistry 2007;282(24):17665-75.
2007: Ito Takuhiro; Wagner Gerhard
Resonance assignments of the alpha subunit of human eukaryotic initiation factor 2 (heIF2alpha).
Journal of biomolecular NMR 2007;38(2):173.
2007: Selenko Philipp; Wagner Gerhard
Looking into live cells with in-cell NMR spectroscopy.
Journal of structural biology 2007;158(2):244-53.
2007: Takeuchi Koh; Roehrl Michael H A; Sun Zhen-Yu J; Wagner Gerhard
Structure of the calcineurin-NFAT complex: defining a T cell activation switch using solution NMR and crystal coordinates.
Structure (London, England : 1993) 2007;15(5):587-97.
2007: Takeuchi Koh; Ng Elise; Malia Thomas J; Wagner Gerhard
1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins.
Journal of biomolecular NMR 2007;38(1):89-98.
2007: Hyberts Sven G; Heffron Gregory J; Tarragona Nestor G; Solanky Kirty; Edmonds Katherine A; Luithardt Harry; Fejzo Jasna; Chorev Michael; Aktas Huseyin; Colson Kimberly; Falchuk Kenneth H; Halperin Jose A; Wagner Gerhard
Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction.
Journal of the American Chemical Society 2007;129(16):5108-16.
2007: McKenna Sean A; Lindhout Darrin A; Kim Insil; Liu Corey W; Gelev Vladimir M; Wagner Gerhard; Puglisi Joseph D
Molecular framework for the activation of RNA-dependent protein kinase.
The Journal of biological chemistry 2007;282(15):11474-86.
2007: Ivanov Dmitri; Tsodikov Oleg V; Kasanov Jeremy; Ellenberger Tom; Wagner Gerhard; Collins Tucker
Domain-swapped dimerization of the HIV-1 capsid C-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4353-8.
2007: Touma Maki; Sun Zhen-Yu J; Clayton Linda K; Marissen Wilfred E; Kruisbeek Ada M; Wagner Gerhard; Reinherz Ellis L
Importance of the CD3gamma ectodomain terminal beta-strand and membrane proximal stalk in thymic development and receptor assembly.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3668-79.
2007: Moerke Nathan J; Aktas Huseyin; Chen Han; Cantel Sonia; Reibarkh Mikhail Y; Fahmy Amr; Gross John D; Degterev Alexei; Yuan Junying; Chorev Michael; Halperin Jose A; Wagner Gerhard
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
Cell 2007;128(2):257-67.
2007: Malia Thomas J; Wagner Gerhard
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.
Biochemistry 2007;46(2):514-25.
2007: Marintchev Assen; Frueh Dominique; Wagner Gerhard
NMR methods for studying protein-protein interactions involved in translation initiation.
Methods in enzymology 2007;430():283-331.
2006: Bordeleau Marie-Eve; Cencic Regina; Lindqvist Lisa; Oberer Monika; Northcote Peter; Wagner Gerhard; Pelletier Jerry
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
Chemistry & biology 2006;13(12):1287-95.
2006: Gelev Vladimir; Aktas Huseyin; Marintchev Assen; Ito Takuhiro; Frueh Dominique; Hemond Michael; Rovnyak David; Debus Mirijam; Hyberts Sven; Usheva Anny; Halperin Jose; Wagner Gerhard
Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance.
Journal of molecular biology 2006;364(3):352-63.
2006: Reibarkh Mikhail; Malia Thomas J; Hopkins Brian T; Wagner Gerhard
Identification of individual protein-ligand NOEs in the limit of intermediate exchange.
Journal of biomolecular NMR 2006;36(1):1-11.
2006: Sastry Mallika; Brown Christopher; Wagner Gerhard; Clark Thomas D
Cyclic peptide helices: a hybrid beta-hairpin/beta-helical supersecondary structure.
Journal of the American Chemical Society 2006;128(33):10650-1.
2006: Selenko Philipp; Serber Zach; Gadea Bedrick; Ruderman Joan; Wagner Gerhard
Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):11904-9.
2006: Yang Fajun; Vought Bryan W; Satterlee John S; Walker Amy K; Jim Sun Z-Y; Watts Jennifer L; DeBeaumont Rosalie; Saito R Mako; Hyberts Sven G; Yang Shaosong; Macol Christine; Iyer Lakshmanan; Tjian Robert; van den Heuvel Sander; Hart Anne C; Wagner Gerhard; Näär Anders M
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.
Nature 2006;442(7103):700-4.
2006: Kitao Akio; Wagner Gerhard
Amplitudes and directions of internal protein motions from a JAM analysis of 15N relaxation data.
Magnetic resonance in chemistry : MRC 2006;44 Spec No():S130-42.
2006: Frueh Dominique P; Sun Zhen-Yu J; Vosburg David A; Walsh Christopher T; Hoch Jeffrey C; Wagner Gerhard
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.
Journal of the American Chemical Society 2006;128(17):5757-63.
2006: Bordeleau Marie-Eve; Mori Ayaka; Oberer Monika; Lindqvist Lisa; Chard Louisa S; Higa Tatsuo; Belsham Graham J; Wagner Gerhard; Tanaka Junichi; Pelletier Jerry
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
Nature chemical biology 2006;2(4):213-20.
2006: Park Sunghyouk; Takeuchi Koh; Wagner Gerhard
Solution structure of the first SRC homology 3 domain of human Nck2.
Journal of biomolecular NMR 2006;34(3):203-8.
2006: von der Haar Tobias; Oku Yuko; Ptushkina Marina; Moerke Nathan; Wagner Gerhard; Gross John D; McCarthy John E G
Folding transitions during assembly of the eukaryotic mRNA cap-binding complex.
Journal of molecular biology 2006;356(4):982-92.
2006: Reibarkh Mikhail; Malia Thomas J; Wagner Gerhard
NMR distinction of single- and multiple-mode binding of small-molecule protein ligands.
Journal of the American Chemical Society 2006;128(7):2160-1.
2006: Selenko Philipp; Wagner Gerhard
NMR mapping of protein interactions in living cells.
Nature methods 2006;3(2):80-1.
2006: Takeuchi Koh; Wagner Gerhard
NMR studies of protein interactions.
Current opinion in structural biology 2006;16(1):109-17.
2006: Frueh Dominique P; Vosburg David A; Walsh Christopher T; Wagner Gerhard
Determination of all nOes in 1H-13C-Me-ILV-U-2H-15N proteins with two time-shared experiments.
Journal of biomolecular NMR 2006;34(1):31-40.
2006: Serber Zach; Selenko Philipp; Hänsel Robert; Reckel Sina; Löhr Frank; Ferrell James E; Wagner Gerhard; Dötsch Volker
Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy.
Nature protocols 2006;1(6):2701-9.
2005: Frueh Dominique P; Arthanari Haribabu; Wagner Gerhard
Unambiguous assignment of NMR protein backbone signals with a time-shared triple-resonance experiment.
Journal of biomolecular NMR 2005;33(3):187-96.
2005: Yamamoto Yasufumi; Singh Chingakham Ranjit; Marintchev Assen; Hall Nathan S; Hannig Ernest M; Wagner Gerhard; Asano Katsura
The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16164-9.
2005: He Chuan; Hus Jean-Christophe; Sun Li Jing; Zhou Pei; Norman Derek P G; Dötsch Volker; Wei Hua; Gross John D; Lane William S; Wagner Gerhard; Verdine Gregory L
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
Molecular cell 2005;20(1):117-29.
2005: Robinson Michael A; Park Sunghyouk; Sun Zhen-Yu J; Silver Pamela A; Wagner Gerhard; Hogle James M
Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
The Journal of biological chemistry 2005;280(42):35723-32.
2005: Sun Zhen-Yu J; Frueh Dominique P; Selenko Philipp; Hoch Jeffrey C; Wagner Gerhard
Fast assignment of 15N-HSQC peaks using high-resolution 3D HNcocaNH experiments with non-uniform sampling.
Journal of biomolecular NMR 2005;33(1):43-50.
2005: Oberer Monika; Marintchev Assen; Wagner Gerhard
Structural basis for the enhancement of eIF4A helicase activity by eIF4G.
Genes & development 2005;19(18):2212-23.
2005: Marintchev Assen; Wagner Gerhard
eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G.
Biochemistry 2005;44(37):12265-72.
2005: Natarajan Amarnath; Guo Yuhong; Arthanari Haribabu; Wagner Gerhard; Halperin Jose A; Chorev Michael
Synthetic studies toward aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics.
The Journal of organic chemistry 2005;70(16):6362-8.
2005: Elkin Sheryl K; Ivanov Dmitri; Ewalt Mark; Ferguson Colin G; Hyberts Sven G; Sun Zhen-Yu J; Prestwich Glenn D; Yuan Junying; Wagner Gerhard; Oettinger Marjorie A; Gozani Or P
A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
The Journal of biological chemistry 2005;280(31):28701-10.
2005: Park Sunghyouk; Isaacson Rivka; Kim Hyoung Tae; Silver Pamela A; Wagner Gerhard
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites.
Structure (London, England : 1993) 2005;13(7):995-1005.
2005: Wagner Gerhard
Ending the prolonged life of cancer cells.
Nature chemical biology 2005;1(1):8-9.
2005: Cherepanov Peter; Sun Zhen-Yu J; Rahman Shaila; Maertens Goedele; Wagner Gerhard; Engelman Alan
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75.
Nature structural & molecular biology 2005;12(6):526-32.
2005: Roehrl Michael H A; Heffron Gregory J; Wagner Gerhard
Correspondence between spin-dynamic phases and pulse program phases of NMR spectrometers.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2005;174(2):325-30.
2005: Sun Zhen-Yu J; Hyberts Sven G; Rovnyak David; Park Sunghyouk; Stern Alan S; Hoch Jeffrey C; Wagner Gerhard
High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H-C evolution and non-uniform sampling.
Journal of biomolecular NMR 2005;32(1):55-60.
2005: Frueh Dominique P; Ito Takuhiro; Li Jr-Shin; Wagner Gerhard; Glaser Steffen J; Khaneja Navin
Sensitivity enhancement in NMR of macromolecules by application of optimal control theory.
Journal of biomolecular NMR 2005;32(1):23-30.
2005: Ivanov Dmitri; Stone James R; Maki Jenny L; Collins Tucker; Wagner Gerhard
Mammalian SCAN domain dimer is a domain-swapped homolog of the HIV capsid C-terminal domain.
Molecular cell 2005;17(1):137-43.
2004: Roehrl Michael H A; Wang Julia Y; Wagner Gerhard
Discovery of small-molecule inhibitors of the NFAT--calcineurin interaction by competitive high-throughput fluorescence polarization screening.
Biochemistry 2004;43(51):16067-75.
2004: Roehrl Michael H A; Wang Julia Y; Wagner Gerhard
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization.
Biochemistry 2004;43(51):16056-66.
2004: Walters Kylie J; Goh Amanda M; Wang Qinghua; Wagner Gerhard; Howley Peter M
Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.
Biochimica et biophysica acta 2004;1695(1-3):73-87.
2004: Sun Zhen-Yu J; Kim Sun Taek; Kim Il Chul; Fahmy Amr; Reinherz Ellis L; Wagner Gerhard
Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16867-72.
2004: Rovnyak D; Hoch J C; Stern A S; Wagner G
Resolution and sensitivity of high field nuclear magnetic resonance spectroscopy.
Journal of biomolecular NMR 2004;30(1):1-10.
2004: Chatwood Lisa L; Müller Jens; Gross John D; Wagner Gerhard; Lippard Stephen J
NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath).
Biochemistry 2004;43(38):11983-91.
2004: Walensky Loren D; Kung Andrew L; Escher Iris; Malia Thomas J; Barbuto Scott; Wright Renee D; Wagner Gerhard; Verdine Gregory L; Korsmeyer Stanley J
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Science (New York, N.Y.) 2004;305(5689):1466-70.
2004: Ito Takuhiro; Marintchev Assen; Wagner Gerhard
Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B.
Structure (London, England : 1993) 2004;12(9):1693-704.
2004: Rovnyak David; Frueh Dominique P; Sastry Mallika; Sun Zhen-Yu J; Stern Alan S; Hoch Jeffrey C; Wagner Gerhard
Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;170(1):15-21.
2004: Marintchev Assen; Wagner Gerhard
Translation initiation: structures, mechanisms and evolution.
Quarterly reviews of biophysics 2004;37(3-4):197-284.
2004: Kato Masato; Ito Takuhiro; Wagner Gerhard; Ellenberger Tom
A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis.
The Journal of biological chemistry 2004;279(29):30554-62.
2004: von der Haar Tobias; Gross John D; Wagner Gerhard; McCarthy John E G
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression.
Nature structural & molecular biology 2004;11(6):503-11.
2004: Roehrl Michael H A; Kang Sunghyun; Aramburu José; Wagner Gerhard; Rao Anjana; Hogan Patrick G
Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(20):7554-9.
2004: Natarajan Amarnath; Moerke Nathan; Fan Yun-Hua; Chen Han; Christ William J; Wagner Gerhard; Halperin Jose A
Synthesis of fluorescein labeled 7-methylguanosinemonophosphate.
Bioorganic & medicinal chemistry letters 2004;14(10):2657-60.
2004: Ito Takuhiro; Wagner Gerhard
Using codon optimization, chaperone co-expression, and rational mutagenesis for production and NMR assignments of human eIF2 alpha.
Journal of biomolecular NMR 2004;28(4):357-67.
2004: Misaghi Shahram; Sun Zhen-Yu J; Stern Patrick; Gaudet Rachelle; Wagner Gerhard; Ploegh Hidde
Structural and functional analysis of human cytomegalovirus US3 protein.
Journal of virology 2004;78(1):413-23.
2003: Gross John D; Moerke Nathan J; von der Haar Tobias; Lugovskoy Alexey A; Sachs Alan B; McCarthy John E G; Wagner Gerhard
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell 2003;115(6):739-50.
2003: Lomakin Ivan B; Kolupaeva Victoria G; Marintchev Assen; Wagner Gerhard; Pestova Tatyana V
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing.
Genes & development 2003;17(22):2786-97.
2003: Bennett Andrew E; Gross John D; Wagner Gerhard
Broadband 13C-13C adiabatic mixing in solution optimized for high fields.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;165(1):59-79.
2003: Freund Christian; Kühne Ronald; Park Sunghyouk; Thiemke Katharina; Reinherz Ellis L; Wagner Gerhard
Structural investigations of a GYF domain covalently linked to a proline-rich peptide.
Journal of biomolecular NMR 2003;27(2):143-9.
2003: Kim Peter W; Sun Zhen-Yu J; Blacklow Stephen C; Wagner Gerhard; Eck Michael J
A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.
Science (New York, N.Y.) 2003;301(5640):1725-8.
2003: Roehrl Michael H A; Hyberts Sven G; Sun Zhen-Yu Jim; Fields Alan P; Wagner Gerhard
Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS.
Journal of biomolecular NMR 2003;26(4):373-4.
2003: Hyberts Sven G; Wagner Gerhard
IBIS--a tool for automated sequential assignment of protein spectra from triple resonance experiments.
Journal of biomolecular NMR 2003;26(4):335-44.
2003: Gozani Or; Karuman Philip; Jones David R; Ivanov Dmitri; Cha James; Lugovskoy Alexey A; Baird Cheryl L; Zhu Hong; Field Seth J; Lessnick Stephen L; Villasenor Jennifer; Mehrotra Bharat; Chen Jian; Rao Vikram R; Brugge Joan S; Ferguson Colin G; Payrastre Bernard; Myszka David G; Cantley Lewis C; Wagner Gerhard; Divecha Nullin; Prestwich Glenn D; Yuan Junying
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Cell 2003;114(1):99-111.
2003: Kato Masato; Ito Takuhiro; Wagner Gerhard; Richardson Charles C; Ellenberger Tom
Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis.
Molecular cell 2003;11(5):1349-60.
2003: Rovnyak David; Filip Claudiu; Itin Boris; Stern Alan S; Wagner Gerhard; Griffin Robert G; Hoch Jeffrey C
Multiple-quantum magic-angle spinning spectroscopy using nonlinear sampling.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;161(1):43-55.
2003: Gross John D; Gelev Vladimir M; Wagner Gerhard
A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes.
Journal of biomolecular NMR 2003;25(3):235-42.
2003: Marintchev Assen; Kolupaeva Victoria G; Pestova Tatyana V; Wagner Gerhard
Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1535-40.
2002: Freund Christian; Kühne Ronald; Yang Hailin; Park Sunghyouk; Reinherz Ellis L; Wagner Gerhard
Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules.
The EMBO journal 2002;21(22):5985-95.
2002: Dormitzer Philip R; Sun Zhen-Yu J; Blixt Ola; Paulson James C; Wagner Gerhard; Harrison Stephen C
Specificity and affinity of sialic acid binding by the rhesus rotavirus VP8* core.
Journal of virology 2002;76(20):10512-7.
2002: Dormitzer Philip R; Sun Zhen-Yu J; Wagner Gerhard; Harrison Stephen C
The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site.
The EMBO journal 2002;21(5):885-97.
2002: Fahmy Amr; Wagner Gerhard
TreeDock: a tool for protein docking based on minimizing van der Waals energies.
Journal of the American Chemical Society 2002;124(7):1241-50.
2002: Lugovskoy Alexey A; Degterev Alexei I; Fahmy Amr F; Zhou Pei; Gross John D; Yuan Junying; Wagner Gerhard
A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors.
Journal of the American Chemical Society 2002;124(7):1234-40.
2002: Walters Kylie J; Kleijnen Maurits F; Goh Amanda M; Wagner Gerhard; Howley Peter M
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
Biochemistry 2002;41(6):1767-77.
2002: Müller Jens; Lugovskoy Alexey A; Wagner Gerhard; Lippard Stephen J
NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase.
Biochemistry 2002;41(1):42-51.
2001: Lin C H; Hare B J; Wagner G; Harrison S C; Maniatis T; Fraenkel E
A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies.
Molecular cell 2001;8(3):581-90.
2001: Kim M; Sun Z Y; Byron O; Campbell G; Wagner G; Wang J; Reinherz E L
Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot".
Journal of molecular biology 2001;312(4):711-20.
2001: Fan C; Wagner G; Li G
Effect of dimethyl sulfoxide on the electron transfer reactivity of hemoglobin.
Bioelectrochemistry (Amsterdam, Netherlands) 2001;54(1):49-51.
2001: Ferentz A E; Walker G C; Wagner G
Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C).
The EMBO journal 2001;20(15):4287-98.
2001: Sun Z J; Kim K S; Wagner G; Reinherz E L
Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer.
Cell 2001;105(7):913-23.
2001: Zhou P; Lugovskoy A A; Wagner G
A solubility-enhancement tag (SET) for NMR studies of poorly behaving proteins.
Journal of biomolecular NMR 2001;20(1):11-4.
2001: Zhou P; Lugovskoy A A; McCarty J S; Li P; Wagner G
Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6051-5.
2001: Hidalgo P; Ansari A Z; Schmidt P; Hare B; Simkovich N; Farrell S; Shin E J; Ptashne M; Wagner G
Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain.
Genes & development 2001;15(8):1007-20.
2001: Lin Y; Dötsch V; Wintner T; Peariso K; Myers L C; Penner-Hahn J E; Verdine G L; Wagner G
Structural basis for the functional switch of the E. coli Ada protein.
Biochemistry 2001;40(14):4261-71.
2001: Goldenberg D P; Koehn R E; Gilbert D E; Wagner G
Solution structure and backbone dynamics of an omega-conotoxin precursor.
Protein science : a publication of the Protein Society 2001;10(3):538-50.
2001: Degterev A; Lugovskoy A; Cardone M; Mulley B; Wagner G; Mitchison T; Yuan J
Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL.
Nature cell biology 2001;3(2):173-82.
2001: Gross J D; Matsuo H; Fletcher M; Sachs A B; Wagner G
Interactions of the eukaryotic translation initiation factor eIF4E.
Cold Spring Harbor symposia on quantitative biology 2001;66():397-402.
2001: Walters K J; Ferentz A E; Hare B J; Hidalgo P; Jasanoff A; Matsuo H; Wagner G
Characterizing protein-protein complexes and oligomers by nuclear magnetic resonance spectroscopy.
Methods in enzymology 2001;339():238-58.
2000: Choe S E; Li L; Matsudaira P T; Wagner G; Shakhnovich E I
Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction.
Journal of molecular biology 2000;304(1):99-115.
2000: Kim K S; Sun Z Y; Wagner G; Reinherz E L
Heterodimeric CD3epsilongamma extracellular domain fragments: production, purification and structural analysis.
Journal of molecular biology 2000;302(4):899-916.
2000: Kang H; Freund C; Duke-Cohan J S; Musacchio A; Wagner G; Rudd C E
SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55.
The EMBO journal 2000;19(12):2889-99.
2000: Battiste J L; Wagner G
Utilization of site-directed spin labeling and high-resolution heteronuclear nuclear magnetic resonance for global fold determination of large proteins with limited nuclear overhauser effect data.
Biochemistry 2000;39(18):5355-65.
2000: Luo X; Fang G; Coldiron M; Lin Y; Yu H; Kirschner M W; Wagner G
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nature structural biology 2000;7(3):224-9.
2000: Ferentz A E; Wagner G
NMR spectroscopy: a multifaceted approach to macromolecular structure.
Quarterly reviews of biophysics 2000;33(1):29-65.
2000: Kitao A; Wagner G
A space-time structure determination of human CD2 reveals the CD58-binding mode.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2064-8.
2000: Battiste J L; Pestova T V; Hellen C U; Wagner G
The eIF1A solution structure reveals a large RNA-binding surface important for scanning function.
Molecular cell 2000;5(1):109-19.
1999: Lugovskoy A A; Zhou P; Chou J J; McCarty J S; Li P; Wagner G
Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.
Cell 1999;99(7):747-55.
1999: Reinherz E L; Tan K; Tang L; Kern P; Liu J; Xiong Y; Hussey R E; Smolyar A; Hare B; Zhang R; Joachimiak A; Chang H C; Wagner G; Wang J
The crystal structure of a T cell receptor in complex with peptide and MHC class II.
Science (New York, N.Y.) 1999;286(5446):1913-21.
1999: Lin Y; Wagner G
Efficient side-chain and backbone assignment in large proteins: application to tGCN5.
Journal of biomolecular NMR 1999;15(3):227-39.
1999: del Río-Portilla F; Gaskell A; Gilbert D; Ladias J A; Wagner G
Solution structure of the hRPABC14.4 subunit of human RNA polymerases.
Nature structural biology 1999;6(11):1039-42.
1999: Hare B J; Wagner G
Application of automated NOE assignment to three-dimensional structure refinement of a 28 kDa single-chain T cell receptor.
Journal of biomolecular NMR 1999;15(2):103-13.
1999: Zhou P; Chou J; Olea R S; Yuan J; Wagner G
Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11265-70.
1999: Hershey P E; McWhirter S M; Gross J D; Wagner G; Alber T; Sachs A B
The Cap-binding protein eIF4E promotes folding of a functional domain of yeast translation initiation factor eIF4G1.
The Journal of biological chemistry 1999;274(30):21297-304.
1999: Freund C; Dötsch V; Nishizawa K; Reinherz E L; Wagner G
The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.
Nature structural biology 1999;6(7):656-60.
1999: Lin Y; Fletcher C M; Zhou J; Allis C D; Wagner G
Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A.
Nature 1999;400(6739):86-9.
1999: Walters K J; Gassner G T; Lippard S J; Wagner G
Structure of the soluble methane monooxygenase regulatory protein B.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7877-82.
1999: Jasanoff A; Song S; Dinner A R; Wagner G; Wiley D C
One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules.
Immunity 1999;10(6):761-8.
1999: Wang J H; Smolyar A; Tan K; Liu J H; Kim M; Sun Z Y; Wagner G; Reinherz E L
Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell 1999;97(6):791-803.
1999: Hare B J; Wyss D F; Osburne M S; Kern P S; Reinherz E L; Wagner G
Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.
Nature structural biology 1999;6(6):574-81.
1999: Sun Z Y; Dötsch V; Kim M; Li J; Reinherz E L; Wagner G
Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies.
The EMBO journal 1999;18(11):2941-9.
1999: Fletcher C M; Pestova T V; Hellen C U; Wagner G
Structure and interactions of the translation initiation factor eIF1.
The EMBO journal 1999;18(9):2631-7.
1999: Chou J J; Li H; Salvesen G S; Yuan J; Wagner G
Solution structure of BID, an intracellular amplifier of apoptotic signaling.
Cell 1999;96(5):615-24.
1998: Kupce E; Schmidt P; Rance M; Wagner G
Adiabatic mixing in the liquid state.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;135(2):361-7.
1998: Nishizawa K; Freund C; Li J; Wagner G; Reinherz E L
Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14897-902.
1998: Jasanoff A; Wagner G; Wiley D C
Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.
The EMBO journal 1998;17(23):6812-8.
1998: Dötsch V; Wagner G
New approaches to structure determination by NMR spectroscopy.
Current opinion in structural biology 1998;8(5):619-23.
1998: Choe S E; Matsudaira P T; Osterhout J; Wagner G; Shakhnovich E I
Folding kinetics of villin 14T, a protein domain with a central beta-sheet and two hydrophobic cores.
Biochemistry 1998;37(41):14508-18.
1998: McGuire A M; Matsuo H; Wagner G
Internal and overall motions of the translation factor eIF4E: cap binding and insertion in a CHAPS detergent micelle.
Journal of biomolecular NMR 1998;12(1):73-88.
1998: Chou J J; Matsuo H; Duan H; Wagner G
Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment.
Cell 1998;94(2):171-80.
1998: Fletcher C M; Wagner G
The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein.
Protein science : a publication of the Protein Society 1998;7(7):1639-42.
1998: Zhu J; Shibasaki F; Price R; Guillemot J C; Yano T; Dötsch V; Wagner G; Ferrara P; McKeon F
Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1.
Cell 1998;93(5):851-61.
1998: Zhou P; Sun L J; Dötsch V; Wagner G; Verdine G L
Solution structure of the core NFATC1/DNA complex.
Cell 1998;92(5):687-96.
1998: Fletcher C M; McGuire A M; Gingras A C; Li H; Matsuo H; Sonenberg N; Wagner G
4E binding proteins inhibit the translation factor eIF4E without folded structure.
Biochemistry 1998;37(1):9-15.
1997: Baleja J D; Thanabal V; Wagner G
Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination.
Journal of biomolecular NMR 1997;10(4):397-401.
1997: Ferentz A E; Opperman T; Walker G C; Wagner G
Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis.
Nature structural biology 1997;4(12):979-83.
1997: Wagner G
An account of NMR in structural biology.
Nature structural biology 1997;4 Suppl():841-4.
1997: Zhang P; Dayie K T; Wagner G
Unusual lack of internal mobility and fast overall tumbling in oxidized flavodoxin from Anacystis nidulans.
Journal of molecular biology 1997;272(3):443-55.
1997: Carroll A S; Gilbert D E; Liu X; Cheung J W; Michnowicz J E; Wagner G; Ellenberger T E; Blackwell T K
SKN-1 domain folding and basic region monomer stabilization upon DNA binding.
Genes & development 1997;11(17):2227-38.
1997: Walters K J; Dayie K T; Reece R J; Ptashne M; Wagner G
Structure and mobility of the PUT3 dimer.
Nature structural biology 1997;4(9):744-50.
1997: Matsuo H; Li H; McGuire A M; Fletcher C M; Gingras A C; Sonenberg N; Wagner G
Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein.
Nature structural biology 1997;4(9):717-24.
1997: Markus M A; Matsudaira P; Wagner G
Refined structure of villin 14T and a detailed comparison with other actin-severing domains.
Protein science : a publication of the Protein Society 1997;6(6):1197-209.
1997: Schmieder P; Stern A S; Wagner G; Hoch J C
Quantification of maximum-entropy spectrum reconstructions.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;125(2):332-9.
1997: Johnson J M; Meiering E M; Wright J E; Pardo J; Rosowsky A; Wagner G
NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase.
Biochemistry 1997;36(15):4399-411.
1997: Wyss D F; Dayie K T; Wagner G
The counterreceptor binding site of human CD2 exhibits an extended surface patch with multiple conformations fluctuating with millisecond to microsecond motions.
Protein science : a publication of the Protein Society 1997;6(3):534-42.
1997: Najfeld I; Dayie K T; Wagner G; Havel T F
A robust method for estimating cross-relaxation rates from simultaneous fits to build-up and decay curves.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;124(2):372-82.
1997: Wolfe S A; Zhou P; Dötsch V; Chen L; You A; Ho S N; Crabtree G R; Wagner G; Verdine G L
Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc.
Nature 1997;385(6612):172-6.
1996: Matsuo H; Kupce E; Wagner G
Resolution and sensitivity gain in HCCH-TOCSY experiments by homonuclear C beta decoupling.
Journal of magnetic resonance. Series B 1996;113(2):190-4.
1996: Matsuo H; Kupce E; Li H; Wagner G
Increased sensitivity in HNCA and HN(CO)CA experiments by selective C beta decoupling.
Journal of magnetic resonance. Series B 1996;113(1):91-6.
1996: Talluri S; Wagner G
An optimized 3D NOESY-HSQC.
Journal of magnetic resonance. Series B 1996;112(2):200-5.
1996: Wyss D F; Wagner G
The structural role of sugars in glycoproteins.
Current opinion in biotechnology 1996;7(4):409-16.
1996: Habazettl J; Myers L C; Yuan F; Verdine G L; Wagner G
Backbone dynamics, amide hydrogen exchange, and resonance assignments of the DNA methylphosphotriester repair domain of Escherichia coli Ada using NMR.
Biochemistry 1996;35(29):9335-48.
1996: Dötsch V; Matsuo H; Wagner G
Amino-acid-type identification for deuterated proteins with a beta-carbon-edited HNCOCACB experiment.
Journal of magnetic resonance. Series B 1996;112(1):95-100.
1996: Dötsch V; Wagner G
Editing for amino-acid type in CBCACONH experiments based on the 13C beta-13C gamma coupling.
Journal of magnetic resonance. Series B 1996;111(3):310-3.
1996: Matsuo H; Kupce E; Li H; Wagner G
Use of selective C alpha pulses for improvement of HN(CA)CO-D and HN(COCA)NH-D experiments.
Journal of magnetic resonance. Series B 1996;111(2):194-8.
1996: Chen J; Peters R; Saha P; Lee P; Theodoras A; Pagano M; Wagner G; Dutta A
A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo.
Nucleic acids research 1996;24(9):1727-33.
1996: Kupce E; Wagner G
Multisite band-selective decoupling in proteins.
Journal of magnetic resonance. Series B 1996;110(3):309-12.
1996: Dötsch V; Oswald R E; Wagner G
Selective identification of threonine, valine, and isoleucine sequential connectivities with a TVI-CBCACONH experiment.
Journal of magnetic resonance. Series B 1996;110(3):304-8.
1996: Markus M A; Dayie K T; Matsudaira P; Wagner G
Local mobility within villin 14T probed via heteronuclear relaxation measurements and a reduced spectral density mapping.
Biochemistry 1996;35(6):1722-32.
1996: Lefevre J F; Dayie K T; Peng J W; Wagner G
Internal mobility in the partially folded DNA binding and dimerization domains of GAL4: NMR analysis of the N-H spectral density functions.
Biochemistry 1996;35(8):2674-86.
1996: Matsuo H; Li H; Wagner G
A sensitive HN(CA)CO experiment for deuterated proteins.
Journal of magnetic resonance. Series B 1996;110(1):112-5.
1996: Dötsch V; Oswald R E; Wagner G
Amino-acid-type-selective triple-resonance experiments.
Journal of magnetic resonance. Series B 1996;110(1):107-11.
1996: Dayie K T; Wagner G; Lefèvre J F
Theory and practice of nuclear spin relaxation in proteins.
Annual review of physical chemistry 1996;47():243-82.
1995: Peng J W; Wagner G
Frequency spectrum of NH bonds in eglin c from spectral density mapping at multiple fields.
Biochemistry 1995;34(51):16733-52.
1995: Zhang P; Talluri S; Deng H; Branton D; Wagner G
Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin.
Structure (London, England : 1993) 1995;3(11):1185-95.
1995: Dayie K T; Wagner G
Carbonyl-carbon relaxation rates reveal a dynamic heterogeneity of the polypeptide backbone in villin 14T.
Journal of magnetic resonance. Series B 1995;109(1):105-8.
1995: Dötsch V; Oswald R E; Wagner G
Water suppression by coherence selection with absorptive lineshape without loss in sensitivity.
Journal of magnetic resonance. Series B 1995;108(3):285-8.
1995: Wyss D F; Choi J S; Li J; Knoppers M H; Willis K J; Arulanandam A R; Smolyar A; Reinherz E L; Wagner G
Conformation and function of the N-linked glycan in the adhesion domain of human CD2.
Science (New York, N.Y.) 1995;269(5228):1273-8.
1995: Krezel A M; Kasibhatla C; Hidalgo P; MacKinnon R; Wagner G
Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Protein science : a publication of the Protein Society 1995;4(8):1478-89.
1995: Wagner G
The importance of being floppy.
Nature structural biology 1995;2(4):255-7.
1995: Meiering E M; Li H; Delcamp T J; Freisheim J H; Wagner G
Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1995;247(2):309-25.
1995: Meiering E M; Wagner G
Detection of long-lived bound water molecules in complexes of human dihydrofolate reductase with methotrexate and NADPH.
Journal of molecular biology 1995;247(2):294-308.
1995: Wyss D F; Choi J S; Wagner G
Composition and sequence specific resonance assignments of the heterogeneous N-linked glycan in the 13.6 kDa adhesion domain of human CD2 as determined by NMR on the intact glycoprotein.
Biochemistry 1995;34(5):1622-34.
1995: Wagner G
E-cadherin: a distant member of the immunoglobulin superfamily.
Science (New York, N.Y.) 1995;267(5196):342.
1994: Wagner G; Wyss D F
Cell surface adhesion receptors.
Current opinion in structural biology 1994;4(6):841-51.
1994: Yang J X; Krezel A; Schmieder P; Wagner G; Havel T F
An evaluation of least-squares fits to COSY spectra as a means of estimating proton-proton coupling constants. II. Applications to polypeptides.
Journal of biomolecular NMR 1994;4(6):827-44.
1994: Arulanandam A R; Kister A; McGregor M J; Wyss D F; Wagner G; Reinherz E L
Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains.
The Journal of experimental medicine 1994;180(5):1861-71.
1994: Myers L C; Cushing T D; Wagner G; Verdine G L
Metal-coordination sphere in the methylated Ada protein-DNA co-complex.
Chemistry & biology 1994;1(2):91-7.
1994: Markus M A; Dayie K T; Matsudaira P; Wagner G
Effect of deuteration on the amide proton relaxation rates in proteins. Heteronuclear NMR experiments on villin 14T.
Journal of magnetic resonance. Series B 1994;105(2):192-5.
1994: Wagner G
Thin end of the wedge.
Nature structural biology 1994;1(8):497-8.
1994: Markus M A; Nakayama T; Matsudaira P; Wagner G
1H, 15N, 13C and 13CO resonance assignments and secondary structure of villin 14T, a domain conserved among actin-severing proteins.
Journal of biomolecular NMR 1994;4(4):553-74.
1994: Schmieder P; Stern A S; Wagner G; Hoch J C
Improved resolution in triple-resonance spectra by nonlinear sampling in the constant-time domain.
Journal of biomolecular NMR 1994;4(4):483-90.
1994: Krezel A M; Wagner G; Seymour-Ulmer J; Lazarus R A
Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting.
Science (New York, N.Y.) 1994;264(5167):1944-7.
1994: Fejzo J; Etzkorn F A; Clubb R T; Shi Y; Walsh C T; Wagner G
The mutant Escherichia coli F112W cyclophilin binds cyclosporin A in nearly identical conformation as human cyclophilin.
Biochemistry 1994;33(19):5711-20.
1994: Baleja J D; Mau T; Wagner G
Recognition of DNA by GAL4 in solution: use of a monomeric protein-DNA complex for study by NMR.
Biochemistry 1994;33(10):3071-8.
1994: Clubb R T; Ferguson S B; Walsh C T; Wagner G
Three-dimensional solution structure of Escherichia coli periplasmic cyclophilin.
Biochemistry 1994;33(10):2761-72.
1994: Markus M A; Nakayama T; Matsudaira P; Wagner G
Solution structure of villin 14T, a domain conserved among actin-severing proteins.
Protein science : a publication of the Protein Society 1994;3(1):70-81.
1994: Peng J W; Wagner G
Investigation of protein motions via relaxation measurements.
Methods in enzymology 1994;239():563-96.
1993: Myers L C; Verdine G L; Wagner G
Solution structure of the DNA methyl phosphotriester repair domain of Escherichia coli Ada.
Biochemistry 1993;32(51):14089-94.
1993: Arulanandam A R; Withka J M; Wyss D F; Wagner G; Kister A; Pallai P; Recny M A; Reinherz E L
The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC'C" face of the human CD2 adhesion domain.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11613-7.
1993: Wyss D F; Withka J M; Knoppers M H; Sterne K A; Recny M A; Wagner G
1H resonance assignments and secondary structure of the 13.6 kDa glycosylated adhesion domain of human CD2.
Biochemistry 1993;32(41):10995-1006.
1993: Schmieder P; Stern A S; Wagner G; Hoch J C
Application of nonlinear sampling schemes to COSY-type spectra.
Journal of biomolecular NMR 1993;3(5):569-76.
1993: Withka J M; Wyss D F; Wagner G; Arulanandam A R; Reinherz E L; Recny M A
Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2.
Structure (London, England : 1993) 1993;1(1):69-81.
1993: Myers L C; Terranova M P; Ferentz A E; Wagner G; Verdine G L
Repair of DNA methylphosphotriesters through a metalloactivated cysteine nucleophile.
Science (New York, N.Y.) 1993;261(5125):1164-7.
1993: Wagner G
Prospects for NMR of large proteins.
Journal of biomolecular NMR 1993;3(4):375-85.
1993: Clubb R T; Thanabal V; Fejzo J; Ferguson S B; Zydowsky L; Baker C H; Walsh C T; Wagner G
Secondary structure and backbone resonance assignments of the periplasmic cyclophilin type peptidyl-prolyl isomerase from Escherichia coli.
Biochemistry 1993;32(25):6391-401.
1993: Adler M; Carter P; Lazarus R A; Wagner G
Cysteine pairing in the glycoprotein IIbIIIa antagonist kistrin using NMR, chemical analysis, and structure calculations.
Biochemistry 1993;32(1):282-9.
1992: Braun W; Vasák M; Robbins A H; Stout C D; Wagner G; Kägi J H; Wüthrich K
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10124-8.
1992: Mau T; Baleja J D; Wagner G
Effects of DNA binding and metal substitution on the dynamics of the GAL4 DNA-binding domain as studied by amide proton exchange.
Protein science : a publication of the Protein Society 1992;1(11):1403-12.
1992: Heinz D W; Hyberts S G; Peng J W; Priestle J P; Wagner G; Grütter M G
Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: functional and structural investigation.
Biochemistry 1992;31(37):8755-66.
1992: Peng J W; Wagner G
Mapping of the spectral densities of N-H bond motions in eglin c using heteronuclear relaxation experiments.
Biochemistry 1992;31(36):8571-86.
1992: Clubb R T; Wagner G
A triple-resonance pulse scheme for selectively correlating amide 1HN and 15N nuclei with the 1H alpha proton of the preceding residue.
Journal of biomolecular NMR 1992;2(4):389-94.
1992: Hyberts S G; Goldberg M S; Havel T F; Wagner G
The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures.
Protein science : a publication of the Protein Society 1992;1(6):736-51.
1992: Reily M D; Thanabal V; Lunney E A; Repine J T; Humblet C C; Wagner G
Design, synthesis and solution structure of a renin inhibitor. Structural constraints from NOE, and homonuclear and heteronuclear coupling constants combined with distance geometry calculations.
FEBS letters 1992;302(1):97-103.
1992: Baleja J D; Marmorstein R; Harrison S C; Wagner G
Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae.
Nature 1992;356(6368):450-3.
1992: Wagner G; Thanabal V; Stockman B J; Peng J W; Nirmala N R; Hyberts S G; Goldberg M S; Detlefsen D J; Clubb R T; Adler M
NMR studies of structure and dynamics of isotope enriched proteins.
Biopolymers 1992;32(4):381-90.
1992: Clubb R T; Thanabal V; Wagner G
A new 3D HN(CA)HA experiment for obtaining fingerprint HN-Halpha peaks in 15N- and 13C-labeled proteins.
Journal of biomolecular NMR 1992;2(2):203-10.
1992: Adler M; Wagner G
Sequential 1H NMR assignments of kistrin, a potent platelet aggregation inhibitor and glycoprotein IIb-IIIa antagonist.
Biochemistry 1992;31(4):1031-9.
1992: Montelione G T; Wüthrich K; Burgess A W; Nice E C; Wagner G; Gibson K D; Scheraga H A
Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry 1992;31(1):236-49.
1992: Stockman B J; Nirmala N R; Wagner G; Delcamp T J; DeYarman M T; Freisheim J H
Sequence-specific 1H and 15N resonance assignments for human dihydrofolate reductase in solution.
Biochemistry 1992;31(1):218-29.
1992: Wagner G; Hyberts S G; Havel T F
NMR structure determination in solution: a critique and comparison with X-ray crystallography.
Annual review of biophysics and biomolecular structure 1992;21():167-98.
1991: Detlefsen D J; Thanabal V; Pecoraro V L; Wagner G
Solution structure of Fe(II) cytochrome c551 from Pseudomonas aeruginosa as determined by two-dimensional 1H NMR.
Biochemistry 1991;30(37):9040-6.
1991: Clubb R T; Thanabal V; Osborne C; Wagner G
1H and 15N resonance assignments of oxidized flavodoxin from Anacystis nidulans with 3D NMR.
Biochemistry 1991;30(31):7718-30.
1991: Adler M; Lazarus R A; Dennis M S; Wagner G
Solution structure of kistrin, a potent platelet aggregation inhibitor and GP IIb-IIIa antagonist.
Science (New York, N.Y.) 1991;253(5018):445-8.
1991: Stockman B J; Nirmala N R; Wagner G; Delcamp T J; DeYarman M T; Freisheim J H
Methotrexate binds in a non-productive orientation to human dihydrofolate reductase in solution, based on NMR spectroscopy.
FEBS letters 1991;283(2):267-9.
1990: Detlefsen D J; Thanabal V; Pecoraro V L; Wagner G
Sequential 1H NMR assignments of iron(II) cytochrome c551 from Pseudomonas aeruginosa.
Biochemistry 1990;29(40):9377-86.
1990: Hyberts S G; Wagner G
Sequence-specific 1H NMR assignments and secondary structure of eglin c.
Biochemistry 1990;29(6):1465-74.
1989: Montelione G T; Winkler M E; Burton L E; Rinderknecht E; Sporn M B; Wagner G
Sequence-specific 1H-NMR assignments and identification of two small antiparallel beta-sheets in the solution structure of recombinant human transforming growth factor alpha.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1519-23.
1989: Wagner G
Heteronuclear nuclear magnetic resonance experiments for studies of protein conformation.
Methods in enzymology 1989;176():93-113.
1988: Schultze P; Wörgötter E; Braun W; Wagner G; Vasák M; Kägi J H; Wüthrich K
Conformation of [Cd7]-metallothionein-2 from rat liver in aqueous solution determined by nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1988;203(1):251-68.
1988: Arseniev A; Schultze P; Wörgötter E; Braun W; Wagner G; Vasák M; Kägi J H; Wüthrich K
Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
Journal of molecular biology 1988;201(3):637-57.
1988: Widmer H; Wagner G; Schweitz H; Lazdunski M; Wüthrich K
The secondary structure of the toxin ATX Ia from Anemonia sulcata in aqueous solution determined on the basis of complete sequence-specific 1H-NMR assignments.
European journal of biochemistry / FEBS 1988;171(1-2):177-92.
1987: Wörgötter E; Wagner G; Vasák M; Kägi J H; Wüthrich K
Sequence-specific 1H-NMR assignments in rat-liver metallothionein-2.
European journal of biochemistry / FEBS 1987;167(3):457-66.
1987: Vasák M; Wörgötter E; Wagner G; Kägi J H; Wüthrich K
Metal co-ordination in rat liver metallothionein-2 prepared with or without reconstitution of the metal clusters, and comparison with rabbit liver metallothionein-2.
Journal of molecular biology 1987;196(3):711-9.
1987: Wagner G; Braun W; Havel T F; Schaumann T; Go N; Wüthrich K
Protein structures in solution by nuclear magnetic resonance and distance geometry. The polypeptide fold of the basic pancreatic trypsin inhibitor determined using two different algorithms, DISGEO and DISMAN.
Journal of molecular biology 1987;196(3):611-39.
1987: Wagner G; Brühwiler D; Wüthrich K
Reinvestigation of the aromatic side-chains in the basic pancreatic trypsin inhibitor by heteronuclear two-dimensional nuclear magnetic resonance.
Journal of molecular biology 1987;196(1):227-31.
1987: Hyberts S G; Märki W; Wagner G
Stereospecific assignments of side-chain protons and characterization of torsion angles in Eglin c.
European journal of biochemistry / FEBS 1987;164(3):625-35.
1987: Leupin W; Wagner G; Denny W A; Wüthrich K
Assignment of the 13C nuclear magnetic resonance spectrum of a short DNA-duplex with 1H-detected two-dimensional heteronuclear correlation spectroscopy.
Nucleic acids research 1987;15(1):267-75.
1987: Wagner G; Frey M H; Neuhaus D; Wörgötter E; Braun W; Vasak M; Kägi J H; Wüthrich K
Spatial structure of rabbit liver metallothionein-2 in solution by NMR.
Experientia. Supplementum 1987;52():149-57.
1986: Wagner G; Brühwiler D
Toward the complete assignment of the carbon nuclear magnetic resonance spectrum of the basic pancreatic trypsin inhibitor.
Biochemistry 1986;25(20):5839-43.

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