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Burkhard Brandt

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Cornelia Liedtke; Jens Packeisen; Ulf Vogt; Burkhard Brandt; Kenneth R Hess; Christian Kersting; Ludwig Kiesel; Eberhard Korsching; Horst Buerger
Systematic analysis of in vitro chemosensitivity and mib-1 expression in molecular breast cancer subtypes.
Lydia M Balz; Kai Bartkowiak; Burkhard Brandt; Bernd Niggemann; Klaus Pantel; Kurt S Zänker; Antje Andreas; Thomas Dittmar
The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination.
Cem Ozel; Jeanette Seidel; Kurt S Zänker; Burkhard Brandt; Sönke Meyer-Staeckling; Bernd Niggemann; Thomas Dittmar
Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk.

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2012: Cornelia Liedtke; Jens Packeisen; Ulf Vogt; Burkhard Brandt; Kenneth R Hess; Christian Kersting; Ludwig Kiesel; Eberhard Korsching; Horst Buerger
Systematic analysis of in vitro chemosensitivity and mib-1 expression in molecular breast cancer subtypes.
European journal of cancer (Oxford, England : 1990) 2012;48(13):2066-74.
2012: Lydia M Balz; Kai Bartkowiak; Burkhard Brandt; Bernd Niggemann; Klaus Pantel; Kurt S Zänker; Antje Andreas; Thomas Dittmar
The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination.
The Journal of pathology 2012;227(2):234-44.
2012: Cem Ozel; Jeanette Seidel; Kurt S Zänker; Burkhard Brandt; Sönke Meyer-Staeckling; Bernd Niggemann; Thomas Dittmar
Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk.
Cell communication and signaling : CCS 2012;10(1):10.
2012: Ronaldo Schuch; Anna Neumann; Konstantin Agelopoulos; Burkhard Brandt; Horst Bürger; Eberhard Korsching
Site-specific chromatin immunoprecipitation: a selective method to individually analyze neighboring transcription factor binding sites in vivo.
BMC research notes 2012;5():109.
2011: Nicole Grabinski; Katharina Grupp; Kai Bartkowiak; Burkhard Brandt; Klaus Pantel; Manfred Jücker
Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.
Cellular signalling 2011;23(12):1952-60.
2011: Daniela Hungermann; Burkhard Brandt; Horst Buerger; Rachael Natrajan; Kathrin Poos; Jorge S Reis-Filho; Hartmut Schmidt; Nicola Tidow; Eberhard Korsching
Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer.
The Journal of pathology 2011;224(4):517-28.
2011: Ulla Kasten-Pisula; Mechthild Krause; Malte Kriegs; Sönke Meyer-Staeckling; Cordula Petersen; Jarob Saker; Benjamin Scherkl; Ala Yaromina; Michael Baumann; Burkhard Brandt; Wolfgang Eicheler; Reidar Grénman; Ekkehard Dikomey
Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification.
International journal of radiation oncology, biology, physics 2011;80(4):1181-8.
2011: Katharina E Effenberger; Elin Borgen; Christine Zu Eulenburg; Kai Bartkowiak; Andrea Grosser; Marit Synnestvedt; Rolf Kaaresen; Burkhard Brandt; Jahn M Nesland; Klaus Pantel; Bjorn Naume
Detection and clinical relevance of early disseminated breast cancer cells depend on their cytokeratin expression pattern.
Breast cancer research and treatment 2011;125(3):729-38.
2011: Juliane Hannemann; Simon A Joosse; Dirk Kemming; Stefan Kurtz; Sönke Meyer-Staeckling; Klaus Pantel; Heike Pospisil; Klaus Püschel; Sabine Riethdorf; Iris Alpers; Jennifer Görndt; Burkhard Brandt
Quantitative high-resolution genomic analysis of single cancer cells.
PloS one 2011;6(11):e26362.
2011: Thomas Dittmar; Sarah Schwitalla; Jeanette Seidel; Sonja Haverkampf; Georg Reith; Sönke Meyer-Staeckling; Burkhard Brandt; Bernd Niggemann; Kurt S Zänker
Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells.
Clinical & experimental metastasis 2011;28(1):75-90.
2010: Natalia Bednarz; Elke Eltze; Axel Semjonow; Michael Rink; Antje Andreas; Lennart Mulder; Juliane Hannemann; Margit Fisch; Klaus Pantel; Heinz-Ulrich G Weier; Krzysztof Piotr Bielawski; Burkhard Brandt
BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(13):3340-8.
2010: Sabine Windhorst; Ralf Fliegert; Christine Blechner; Katharina Möllmann; Zara Hosseini; Thomas Günther; Maike Eiben; Lydia Chang; Hong-Ying Lin; Werner Fanick; Udo Schumacher; Burkhard Brandt; Georg W Mayr
Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.
The Journal of biological chemistry 2010;285(8):5541-54.
2010: Konstantin Agelopoulos; Burkhard Greve; Hartmut Schmidt; Heike Pospisil; Stefan Kurtz; Kai Bartkowiak; Antje Andreas; Marek Wieczorek; Eberhard Korsching; Horst Buerger; Burkhard Brandt
Selective regain of egfr gene copies in CD44+/CD24-/low breast cancer cellular model MDA-MB-468.
BMC cancer 2010;10():78.
2008: Konstantin Agelopoulos; Horst Buerger; Burkhard Brandt
Allelic imbalances of the egfr gene as key events in breast cancer progression--the concept of committed progenitor cells.
Current cancer drug targets 2008;8(5):431-45.
2008: Christian Kersting; Konstantin Agelopoulos; Hartmut Schmidt; Eberhard Korsching; Christian August; Georg Gosheger; Uta Dirksen; Herbert Juergens; Winfried Winkelmann; Burkhard Brandt; Stefan S Bielack; Horst Buerger; Carsten Gebert
Biological importance of a polymorphic CA sequence within intron 1 of the epidermal growth factor receptor gene (EGFR) in high grade central osteosarcomas.
Genes, chromosomes & cancer 2008;47(8):657-64.
2008: Elke Eltze; H Schmidt; A Semjonow; Burkhard Brandt
Translating genetic pathways to protein networks for cancer sub-typing.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19 Suppl 5():v44-7.
2008: Klaus Pantel; Ruud H Brakenhoff; Burkhard Brandt
Detection, clinical relevance and specific biological properties of disseminating tumour cells.
Nature reviews. Cancer 2008;8(5):329-40.
2007: Thomas Fillies; Mirco Jogschies; Johannes Kleinheinz; Burkhard Brandt; Ulrich Joos; Horst Buerger
Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.
Oncology reports 2007;18(3):639-43.
2007: Christian Kersting; Carsten Gebert; Konstantin Agelopoulos; Hartmut Schmidt; Paulus van Diest; Herbert Juergens; Winfried Winkelmann; Matthias Kevric; Georg Gosheger; Burkhard Brandt; Stefan S Bielack; Horst Buerger
Epidermal growth factor receptor expression in high-grade osteosarcomas is associated with a good clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(10):2998-3005.
2007: Thomas Fillies; Mike Woltering; Burkhard Brandt; Jean-Paul Van Diest; Richard Werkmeister; Ulrich Joos; Horst Buerger
Cell cycle regulating proteins p21 and p27 in prognosis of oral squamous cell carcinomas.
Oncology reports 2007;17(2):355-9.
2007: H Schmidt; A Semjonow; K Csiszar; E Korsching; Burkhard Brandt; E Eltze
[Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2007;91():302-7.
2007: Konstantin Agelopoulos; Christian Kersting; Eberhard Korsching; Hartmut Schmidt; Arno Kuijper; Christian August; Pia Wülfing; Joke Tio; Werner Boecker; Paulus van Diest; Burkhard Brandt; Horst Buerger
Egfr amplification specific gene expression in phyllodes tumours of the breast.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(6):443-51.
2006: Burkhard Brandt; Sönke Meyer-Staeckling; Hartmut Schmidt; Konstantin Agelopoulos; Horst Buerger
Mechanisms of egfr gene transcription modulation: relationship to cancer risk and therapy response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7252-60.
2006: Hartmut Schmidt; Gabriela DeAngelis; Elke Eltze; Iris Gockel; Axel Semjonow; Burkhard Brandt
Asynchronous growth of prostate cancer is reflected by circulating tumor cells delivered from distinct, even small foci, harboring loss of heterozygosity of the PTEN gene.
Cancer research 2006;66(18):8959-65.
2006: Jan-Henrik Mikesch; Horst Buerger; Ronald Simon; Burkhard Brandt
Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies.
Biochimica et biophysica acta 2006;1766(1):42-52.
2006: Marzena Wełnicka-Jaśkiewicz; Anna Zaczek; Burkhard Brandt; Krzysztof Piotr Bielawski; Janusz Jaśkiewicz; Krzysztof Konopa; Jacek Jassem
(CA)n microsatellite polymorphism of ERBB-1 in breast cancer.
European journal of cancer (Oxford, England : 1990) 2006;42(12):1698-701.
2006: Christian Kersting; Jens Packeisen; Benedikt Leidinger; Burkhard Brandt; R von Wasielewski; Winfried Winkelmann; Paulus van Diest; Georg Gosheger; Horst Buerger
Pitfalls in immunohistochemical assessment of EGFR expression in soft tissue sarcomas.
Journal of clinical pathology 2006;59(6):585-90.
2006: Pia Wülfing; Julia Borchard; Horst Buerger; Stefan Heidl; Kurt S Zänker; Ludwig Kiesel; Burkhard Brandt
HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1715-20.
2006: Jan-Henrik Mikesch; Katrin Schier; Antje Roetger; Ronald Simon; Horst Buerger; Burkhard Brandt
The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(5-6):223-32.
2006: Dirk Kemming; Ulf Vogt; Nicola Tidow; Claus M Schlotter; Horst Bürger; M W Helms; Eberhard Korsching; Andreas Granetzny; Ahmad Boseila; Ludger Hillejan; A Marra; Y Ergönenc; H Adigüzel; Burkhard Brandt
Whole genome expression analysis for biologic rational pathway modeling: application in cancer prognosis and therapy prediction.
Molecular diagnosis & therapy 2006;10(5):271-80.
2006: Eberhard Korsching; Konstantin Agelopolous; Hartmut Schmidt; Inka Buchroth; Georg Gosheger; Pia Wülfing; Werner Boecker; Burkhard Brandt; Horst Buerger
Improvements in the analysis strategy make single nucleotide polymorphism analysis a powerful tool in the detection and characterization of amplified chromosomal regions in human tumors.
Pathobiology : journal of immunopathology, molecular and cellular biology 2006;73(1):18-25.
2006: Mike W Helms; Burkhard Brandt; Christopher H Contag
Options for visualizing metastatic disease in the living body.
Contributions to microbiology 2006;13():209-31.
2006: Thomas Fillies; Richard Werkmeister; Jens Packeisen; Burkhard Brandt; Philippe Morin; Dieter Weingart; Ulrich Joos; Horst Buerger
Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity.
BMC cancer 2006;6():10.
2006: Christian Kersting; Arno Kuijper; Hartmut Schmidt; Jens Packeisen; Cornelia Liedtke; Nicola Tidow; Christian Gustmann; Bernd Hinrichs; Pia Wülfing; Joke Tio; Werner Boecker; Paulus van Diest; Burkhard Brandt; Horst Buerger
Amplifications of the epidermal growth factor receptor gene (egfr) are common in phyllodes tumors of the breast and are associated with tumor progression.
Laboratory investigation; a journal of technical methods and pathology 2006;86(1):54-61.
2005: Burkhard Brandt; Dirk Kemming; Jens Packeisen; R Simon; M Helms; U Feldmann; A Matuschek; Christian Kersting; Bernd Hinrichs; J-M Bidart; Dominique Bellet; K Bartkowiak; N Dankbar; Thomas Dittmar; Guido Sauter; W Boecker; Horst Buerger
Expression of early placenta insulin-like growth factor in breast cancer cells provides an autocrine loop that predominantly enhances invasiveness and motility.
Endocrine-related cancer 2005;12(4):823-37.
2005: Thomas Fillies; Horst Buerger; Christoph Gaertner; C August; Burkhard Brandt; Ulrich Joos; Richard Werkmeister
Catenin expression in T1/2 carcinomas of the floor of the mouth.
International journal of oral and maxillofacial surgery 2005;34(8):907-11.
2005: Jens Packeisen; K Nakachi; Werner Boecker; Burkhard Brandt; Horst Buerger
Cytogenetic differences in breast cancer samples between German and Japanese patients.
Journal of clinical pathology 2005;58(10):1101-3.
2005: Daniel Palm; Kerstin Lang; Burkhard Brandt; Kurt S Zaenker; Frank Entschladen
In vitro and in vivo imaging of cell migration: two interdepending methods to unravel metastasis formation.
Seminars in cancer biology 2005;15(5):396-404.
2005: Burkhard Brandt; Christoph Heyder; Eva Gloria-Maercker; Wolfgang Hatzmann; Antje Rötger; Dirk Kemming; Kurt S Zänker; Frank Entschladen; Thomas Dittmar
3D-extravasation model -- selection of highly motile and metastatic cancer cells.
Seminars in cancer biology 2005;15(5):387-95.
2005: Uwe Joosten; Alexander Joist; G Gosheger; Ulf Liljenqvist; Burkhard Brandt; Christof von Eiff
Effectiveness of hydroxyapatite-vancomycin bone cement in the treatment of Staphylococcus aureus induced chronic osteomyelitis.
Biomaterials 2005;26(25):5251-8.
2005: Eberhard Korsching; Jens Packeisen; Cornelia Liedtke; Daniela Hungermann; Pia Wülfing; Paulus van Diest; Burkhard Brandt; Werner Boecker; Horst Buerger
The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential?
The Journal of pathology 2005;206(4):451-7.
2005: Krzysztof Piotr Bielawski; P Klos; Marzena Welnicka-Jaskiewicz; M Tidow; Burkhard Brandt; Bogdan Falkiewicz; Anna Zaczek
An epidermal growth factor receptor intron 1 polymorphism in healthy women in Poland.
The International journal of biological markers 2005;20(3):184-8.
2005: Anna Zaczek; Burkhard Brandt; Krzysztof Piotr Bielawski
The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches.
Histology and histopathology 2005;20(3):1005-15.
2005: Mike W Helms; Jens Packeisen; Christian August; Birgit Schittek; Werner Boecker; Burkhard Brandt; Horst Buerger
First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.
The Journal of pathology 2005;206(3):366-76.
2005: Anna Zaczek; Marzena Welnicka-Jaskiewicz; Horst Buerger; Burkhard Brandt; Krzysztof Piotr Bielawski
Modified direct-double-differential PCR for gene dosage quantification of HER2.
Oncology reports 2005;13(5):971-5.
2005: Burkhard Brandt; Jan-Henrik Mikesch; Ronald Simon; Antje Rötger; Dirk Kemming; Katrin Schier; Guido Sauter; Horst Bürger
Selective expression of a splice variant of decay-accelerating factor in c-erbB-2-positive mammary carcinoma cells showing increased transendothelial invasiveness.
Biochemical and biophysical research communications 2005;329(1):318-23.
2005: Horst Bürger; Dirk Kemming; Mike W Helms; U Feldmann; A Matuschek; Werner Böcker; Burkhard Brandt
[Expression of early placenta insulin-like growth factor (EPIL) in breast cancer cells provides an autocrine loop with enhancement of predominantly HER-2-related invasivity].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2005;89():201-6.
2005: Thomas Fillies; Richard Werkmeister; Paulus van Diest; Burkhard Brandt; Ulrich Joos; Horst Buerger
HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor.
BMC cancer 2005;5():84.
2005: Olaf Bettendorf; Hartmut Schmidt; Elke Eltze; Iris Gockel; Axel Semjonow; Horst Bürger; Werner Böcker; Burkhard Brandt
Cytogenetic changes and loss of heterozygosity in atypical adenomatous hyperplasia, in carcinoma of the prostate and in non-neoplastic prostate tissue using comparative genomic hybridization and multiplex-PCR.
International journal of oncology 2005;26(1):267-74.
2004: Uwe Joosten; Alexander Joist; Thomas Frebel; Burkhard Brandt; Sven Diederichs; Christof von Eiff
Evaluation of an in situ setting injectable calcium phosphate as a new carrier material for gentamicin in the treatment of chronic osteomyelitis: studies in vitro and in vivo.
Biomaterials 2004;25(18):4287-95.
2004: Horst Buerger; Jens Packeisen; Almuth Boecker; Nicola Tidow; Christian Kersting; Krzysztof Piotr Bielawski; Jorma Isola; Yasushi Yatabe; Kei Nakachi; Werner Boecker; Burkhard Brandt
Allelic length of a CA dinucleotide repeat in the egfr gene correlates with the frequency of amplifications of this sequence--first results of an inter-ethnic breast cancer study.
The Journal of pathology 2004;203(1):545-50.
2004: Christian Kersting; Nicola Tidow; Hartmut Schmidt; Cornelia Liedtke; Joerg Neumann; Werner Boecker; Paulus van Diest; Burkhard Brandt; Horst Buerger
Gene dosage PCR and fluorescence in situ hybridization reveal low frequency of egfr amplifications despite protein overexpression in invasive breast carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2004;84(5):582-7.
2004: Eberhard Korsching; Jens Packeisen; Mike W Helms; Christian Kersting; Reinhard Voss; Paulus van Diest; Burkhard Brandt; ELSKEN VAN DER WALL; Werner Boecker; Horst Bürger
Deciphering a subgroup of breast carcinomas with putative progression of grade during carcinogenesis revealed by comparative genomic hybridisation (CGH) and immunohistochemistry.
British journal of cancer 2004;90(7):1422-8.
2004: H Schmidt; G De Angelis; Olaf Bettendorf; Elke Eltze; Axel Semjonow; G Knichwitz; Burkhard Brandt
Frequent detection and immunophenotyping of prostate-derived cell clusters in the peripheral blood of prostate cancer patients.
The International journal of biological markers 2004;19(2):93-9.
2004: Carsten Müller-Tidow; Joachim Schwäble; Björn Steffen; Nicola Tidow; Burkhard Brandt; Kerstin Becker; Eric Schulze-Bahr; Hartmut Halfter; Ulf Vogt; Ralf Metzger; Paul M Schneider; Thomas Büchner; Christian Brandts; Wolfgang E Berdel; Hubert Serve
High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(4):1241-9.
2004: Y Katterle; Burkhard Brandt; S F Dowdy; Bernd Niggemann; Kurt S Zänker; Thomas Dittmar
Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells.
British journal of cancer 2004;90(1):230-5.
2004: Burkhard Brandt; Silke Hermann; Kurt Straif; Nicola Tidow; Horst Buerger; Jenny Chang-Claude
Modification of breast cancer risk in young women by a polymorphic sequence in the egfr gene.
Cancer research 2004;64(1):7-12.
2003: Ping Ji; Sven Diederichs; Wenbing Wang; Sebastian Böing; Ralf Metzger; Paul M Schneider; Nicola Tidow; Burkhard Brandt; Horst Buerger; Etmar Bulk; Michael Thomas; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer.
Oncogene 2003;22(39):8031-41.
2003: Konstantin Agelopoulos; Nicola Tidow; Eberhard Korsching; Reinhard Voss; Bernd Hinrichs; Burkhard Brandt; Werner Boecker; Horst Buerger
Molecular cytogenetic investigations of synchronous bilateral breast cancer.
Journal of clinical pathology 2003;56(9):660-5.
2003: Frank Oberpenning; Stefan Hetzel; Christoph Weining; Burkhard Brandt; Gabriela De Angelis; Achim Heinecke; Michael Lein; Paolo Fornara; Hans-Peter Schmid; Lothar Hertle; Axel Semjonow
Semi-quantitative immunochromatographic test for prostate specific antigen in whole blood: tossing the coin to predict prostate cancer?
European urology 2003;43(5):478-84.
2003: Nicola Tidow; Almuth Boecker; Hartmut Schmidt; Konstantin Agelopoulos; Werner Boecker; Horst Buerger; Burkhard Brandt
Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development.
Cancer research 2003;63(6):1172-8.
2003: R Keller; Burkhard Brandt; Hans-Joachim Terpe; Günther Winde; Ernst Christoph Foerster; Wolfram Domschke
Cytology and image cytometry after colonic lavage: a complementary diagnostic tool in patients with ulcerative colitis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35(1):24-31.
2003: Frank Oberpenning; Christoph Weining; Burkhard Brandt; Gabriela De Angelis; Achim Heinecke; Michael Hamm; Petra Stieber; Lothar Hertle; Hans-Peter Schmid; Axel Semjonow
A new modification of the Chiron ACS assay for total prostate-specific antigen achieves equimolar response characteristics and improves the detection of prostate cancer.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(1):90-4.
2002: Frank Oberpenning; Christoph Weining; Burkhard Brandt; Gabriela De Angelis; Achim Heinecke; Michael Hamm; Petra Stieber; Lothar Hertle; Hans-Peter Schmid; Axel Semjonow
Combining free and total prostate specific antigen assays from different manufacturers: the pitfalls.
European urology 2002;42(6):577-82; discussion 582.
2002: Eberhard Korsching; Jens Packeisen; Konstantin Agelopoulos; Martin Eisenacher; Reinhard Voss; Jorma Isola; Paulus van Diest; Burkhard Brandt; Werner Boecker; Horst Buerger
Cytogenetic alterations and cytokeratin expression patterns in breast cancer: integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis.
Laboratory investigation; a journal of technical methods and pathology 2002;82(11):1525-33.
2002: Thomas Dittmar; Anja Husemann; Yvonne Schewe; Jerzy-Roch Nofer; Bernd Niggemann; Kurt S Zänker; Burkhard Brandt
Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1823-5.
2002: Werner Böcker; Roland Moll; Christopher Poremba; Roland Holland; Paulus van Diest; Peter Dervan; Horst Bürger; Daniel Wai; Raihanatou Ina Diallo; Burkhard Brandt; Hermann Herbst; Ansgar Schmidt; Markus M Lerch; Igor B Buchwallow
Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept.
Laboratory investigation; a journal of technical methods and pathology 2002;82(6):737-46.
2002: Niels Reinmuth; Burkhard Brandt; Michael Semik; Wolf-Peter Kunze; Richard Achatzy; Hans H Scheld; Petra Broermann; Wolfgang E Berdel; Hans-Nicol Macha; Michael Thomas
Prognostic impact of Cyfra21-1 and other serum markers in completely resected non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2002;36(3):265-70.
2002: Petra Broermann; Klaus Junker; Burkhard Brandt; Achim Heinecke; Lutz Freitag; Folker Klinke; Wolfgang E Berdel; Michael Thomas
Trimodality treatment in Stage III nonsmall cell lung carcinoma: prrognostic impact of K-ras mutations after neoadjuvant therapy.
Cancer 2002;94(7):2055-62.
2002: Britta S Kubens; Julia C Feldner; Burkhard Brandt; Kurt S Zänker
Migrating and circulating breast carcinoma cells are within active phases of the cell cycle.
Anticancer research 2002;22(2A):899-903.
2002: Burkhard Brandt; Antje Roetger; Jean-Michel Bidart; Jens Packeisen; Katrin Schier; Jan-Henrik Mikesch; Dirk Kemming; Werner Boecker; Dihua Yu; Horst Buerger
Early placenta insulin-like growth factor (pro-EPIL) is overexpressed and secreted by c-erbB-2-positive cells with high invasion potential.
Cancer research 2002;62(4):1020-4.
2002: Julia C Feldner; Burkhard Brandt
Cancer cell motility--on the road from c-erbB-2 receptor steered signaling to actin reorganization.
Experimental cell research 2002;272(2):93-108.
2002: Burkhard Brandt
Molecular diagnostics of solid malignant tumours.
Clinical laboratory 2002;48(11-12):605-15.
2001: Horst Buerger; Hartmut Schmidt; A Beckmann; Kurt S Zänker; Werner Boecker; Burkhard Brandt
Genetic characterisation of invasive breast cancer: a comparison of CGH and PCR based multiplex microsatellite analysis.
Journal of clinical pathology 2001;54(11):836-40.
2001: Axel Semjonow; Frank Oberpenning; Christoph Weining; Margarete Schön; Burkhard Brandt; Gabriela De Angelis; Achim Heinecke; Michael Hamm; Petra Stieber; Lothar Hertle; Hans-Peter Schmid
Do modifications of nonequimolar assays for total prostate-specific antigen improve detection of prostate cancer?
Clinical chemistry 2001;47(8):1472-5.
2001: Marius Nap; Gero Brockhoff; Burkhard Brandt; Ruth Knuechel; Mathie Leers; H Schmidt; G De Angelis; Elke Eltze; A Semjonow
Flow cytometric DNA and phenotype analysis in pathology. A meeting report of a symposium at the annual conference of the German Society of Pathology, Kiel, Germany, 6-9 June 2000.
Virchows Archiv : an international journal of pathology 2001;438(5):425-32.
2001: Burkhard Brandt; Hartmut Schmidt; G de Angelis; Kurt S Zänker
Predictive laboratory diagnostics in oncology utilizing blood-borne cancer cells--current best practice and unmet needs.
Cancer letters 2001;162 Suppl():S11-S16.
2000: Niels Reinmuth; Burkhard Brandt; W P Kunze; Klaus Junker; Michael Thomas; R Achatzy; Hans H Scheld; Michael Semik
Ploidy, expression of erbB1, erbB2, P53 and amplification of erbB1, erbB2 and erbB3 in non-small cell lung cancer.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(5):991-6.
2000: Agnes Bánkfalvi; Ronald Simon; Burkhard Brandt; Horst Bürger; I Vollmer; Barbara Dockhorn-Dworniczak; Ralph J Lellé; Werner Boecker
Comparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in breast carcinoma tissues for diagnostic use.
Histopathology 2000;37(5):411-9.
2000: Thomas Dittmar; F Schäfer; Burkhard Brandt; Kurt S Zänker
Accelerated assessing of antisense RNA efficacy using a chimeric enhanced green fluorescent protein-antisense RNA-producing vector.
Antisense & nucleic acid drug development 2000;10(5):401-8.
2000: Axel Semjonow; Gabriela De Angelis; Frank Oberpenning; Hans-Peter Schmid; Burkhard Brandt; Lothar Hertle
The clinical impact of different assays for prostate specific antigen.
BJU international 2000;86(5):590-7.
2000: F Gebhardt; H Bürger; Burkhard Brandt
Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations--a link between genetics and epigenetics.
Histology and histopathology 2000;15(3):929-36.
2000: G De Angelis; Burkhard Brandt; HP Schmid; A Semjonow
[From antigen to tumor marker. Results of research regarding PSA and its clinical applications].
Der Urologe. Ausg. A 2000;39(4):309-12.
2000: Marc Azemar; Manfred Schmidt; F Arlt; P Kennel; Burkhard Brandt; A Papadimitriou; Bernd Groner; Winfried S Wels
Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo.
International journal of cancer. Journal international du cancer 2000;86(2):269-75.
2000: Horst Buerger; F Gebhardt; Hartmut Schmidt; A Beckmann; K Hutmacher; Ronald Simon; Ralph Lelle; Werner Boecker; Burkhard Brandt
Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression.
Cancer research 2000;60(4):854-7.
2000: Thomas Dittmar; Burkhard Brandt; K Lang; Kurt S Zaenker; Frank Entschladen
Lessons from tumor and immunocompetent cells. The quantitative engagement of ligand-receptor interactions modulates stop-and-go behavior as well as proliferation.
Medicina 2000;60 Suppl 2():27-33.
2000: Richard Werkmeister; Burkhard Brandt; Ulrich Joos
Clinical relevance of erbB-1 and -2 oncogenes in oral carcinomas.
Oral oncology 2000;36(1):100-5.
2000: Burkhard Brandt; H Schmitt; Julia C Feldner; Ralph J Lellé; Axel Semjonow; A Beckmann
Blood-borne cancer cells--quo vadis?
The International journal of biological markers 2000;15(1):111-3.
2000: F Gebhardt; H Bürger; Burkhard Brandt
Modulation of EGFR gene transcription by a polymorphic repetitive sequence--a link between genetics and epigenetics.
The International journal of biological markers 2000;15(1):105-10.
1999: Richard Werkmeister; Burkhard Brandt; Ulrich Joos
Aberrations of erbB-1 and erbB-2 oncogenes in non-dysplastic leukoplakias of the oral cavity.
The British journal of oral & maxillofacial surgery 1999;37(6):477-80.
1999: Burkhard Brandt; Antje Roetger; Thomas Dittmar; G Nikolai; M Seeling; A Merschjann; Jerzy-Roch Nofer; G Dehmer-Möller; R Junker; Gerd Assmann; Kurt S Zaenker
c-erbB-2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(14):1939-49.
1999: Richard Werkmeister; Thomas Fillies; Burkhard Brandt; B Groner; W Weis; Ulrich Joos
Chemosensitivity testing of oral cancer cells treated with a p185neu-specific agent.
European journal of oral sciences 1999;107(5):338-43.
1999: R Junker; Burkhard Brandt; Axel Semjonow; Michael Erren; C Zechel; G Assmann
The biologic lower detection limit of six ultrasensitive PSA assays.
Anticancer research 1999;19(4A):2625-8.
1999: F Gebhardt; Kurt S Zänker; Burkhard Brandt
Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1.
The Journal of biological chemistry 1999;274(19):13176-80.
1999: R Keller; Burkhard Brandt; Hans-Joachim Terpe; Günther Winde; Ernst Christoph Foerster; Wolfram Domschke
Density gradient centrifugation of colonic fluid after segmental lavage: a method of purification of exfoliative epithelial colonic cells for cytological interpretation and image cytometry in patients with long-standing ulcerative colitis.
The American journal of gastroenterology 1999;94(2):404-9.
1999: A Beckmann; Ulf Vogt; N Huda; Kurt S Zänker; Burkhard Brandt
Direct-double-differential PCR for gene dosage quantification of c-myc.
Clinical chemistry 1999;45(1):141-3.
1998: Antje Roetger; A Merschjann; Thomas Dittmar; C Jackisch; Angelika Barnekow; Burkhard Brandt
Selection of potentially metastatic subpopulations expressing c-erbB-2 from breast cancer tissue by use of an extravasation model.
The American journal of pathology 1998;153(6):1797-806.
1998: F Gebhardt; Kurt S Zänker; Burkhard Brandt
Differential expression of alternatively spliced c-erbB-2 mRNA in primary tumors, lymph node metastases, and bone marrow micrometastases from breast cancer patients.
Biochemical and biophysical research communications 1998;247(2):319-23.
1998: A Beckmann; F Gebhardt; Burkhard Brandt
Direct quantification of polymerase chain reaction fragments using field-amplified sample injection in capillary zone electrophoresis for gene dosage estimation.
Journal of chromatography. B, Biomedical sciences and applications 1998;710(1-2):75-80.
1998: Burkhard Brandt; Antje Roetger; S Heidl; C Jackisch; Ralph Lelle; Gerd Assmann; Kurt S Zänker
Isolation of blood-borne epithelium-derived c-erbB-2 oncoprotein-positive clustered cells from the peripheral blood of breast cancer patients.
International journal of cancer. Journal international du cancer 1998;76(6):824-8.
1997: Burkhard Brandt; A Beckmann; F Gebhardt; Antje Rötger; C Jackisch; Gerd Assmann; Kurt S Zänker
Translational research studies of erbB oncogenes: selection strategies for breast cancer treatment.
Cancer letters 1997;118(2):143-51.
1997: Günther Winde; K W Schmid; Burkhard Brandt; O Müller; H Osswald
Clinical and genomic influence of sulindac on rectal mucosa in familial adenomatous polyposis.
Diseases of the colon and rectum 1997;40(10):1156-68; discussion 1168-9.
1997: R Junker; Burkhard Brandt; C Zechel; G Assmann
Comparison of prostate-specific antigen (PSA) measured by four combinations of free PSA and total PSA assays.
Clinical chemistry 1997;43(9):1588-94.
1997: Ulrich Schäfer; Oliver Micke; G Hampel; Burkhard Brandt; A Bovenschulte; Axel Semjonow; Normann Willich
The use of prostate-specific antigen (PSA) for the monitoring of radiation therapy in prostate cancer.
Anticancer research 1997;17(4B):2983-6.
1997: Antje Roetger; Burkhard Brandt; Angelika Barnekow
Competitive-differential polymerase chain reaction for gene dosage estimation of erbB-1 (egfr), erbB-2, and erbB-3 oncogenes.
DNA and cell biology 1997;16(4):443-8.
1997: Burkhard Brandt; C Griwatz; O Brinkmann; Kurt S Zänker
Circulating prostate-specific antigen/CD14-double-positive cells: a biomarker indicating low risk for hematogeneous metastasis of prostate cancer.
Journal of the National Cancer Institute 1997;89(2):174.
1996: Richard Werkmeister; Burkhard Brandt; Ulrich Joos
The erbB oncogenes as prognostic markers in oral squamous cell carcinomas.
American journal of surgery 1996;172(6):681-3.
1996: Günther Winde; K W Schmid; Norbert Lügering; R Fischer; Burkhard Brandt; T Berns; H Bünte
Results and prognostic factors of splenectomy in idiopathic thrombocytopenic purpura.
Journal of the American College of Surgeons 1996;183(6):565-74.
1996: Ralf Junker; Burkhard Brandt; Axel Semjonow; G Assmann
Measurement of prostate-specific antigen: no advantage to ultrasensitive assays?
Journal of the National Cancer Institute 1996;88(21):1594-5.
1996: Burkhard Brandt; C Griwatz; S Heidl; Gerd Assmann; Kurt S Zänker
Detection of the metastatic potential of blood-borne and immunomagnetically enriched epithelial cells by quantitative erbB-2 RT-PCR.
Clinical & experimental metastasis 1996;14(4):399-408.
1996: Burkhard Brandt; M Thomas; M von Eiff; Gerd Assmann
Immunophenotyping of lymphocytes obtained by bronchoalveolar lavage: description of an all-purpose tricolor flow cytometric application.
Journal of immunological methods 1996;194(1):95-102.
1995: M Thomas; M von Eiff; Burkhard Brandt; A Heinecke; J van de Loo
Immunophenotyping of lymphocytes in bronchoalveolar lavage fluid. A new flow cytometric method vs standard immunoperoxidase technique.
Chest 1995;108(2):464-9.
1995: Axel Semjonow; Burkhard Brandt; Frank Oberpenning; Lothar Hertle
[Different determination methods make interpretation of prostate-specific antigen more difficult].
Der Urologe. Ausg. A 1995;34(4):303-15.
1995: C Griwatz; Burkhard Brandt; Gerd Assmann; Kurt S Zänker
An immunological enrichment method for epithelial cells from peripheral blood.
Journal of immunological methods 1995;183(2):251-65.
1995: Burkhard Brandt; Ulf Vogt; Claus M Schlotter; Christian Jackisch; Richard Werkmeister; M Thomas; M von Eiff; Ulrich Bosse; Gerd Assmann; Kurt S Zänker
Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: double-differential polymerase chain reaction (ddPCR) for clinical diagnosis.
Gene 1995;159(1):35-42.
1994: P G Schneider; Christian Jackisch; Burkhard Brandt
Endocrine management of breast cancer.
International journal of fertility and menopausal studies 1994;39 Suppl 2():115-27.
1988: D Seitzer; Burkhard Brandt; F K Beller; G Assmann
[The tumor marker CA 15-3 in breast cancer in serum and cell compartments as an additional prognostic criterion].
Geburtshilfe und Frauenheilkunde 1988;48(5):305-8.