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Miguel Viveiros

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Sofia Costa; José Melo-Cristino; Cláudia Mourato; Miguel Viveiros; Leonard Amaral; Isabel Couto
Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain.
Liliana Rodrigues; Cristina Villellas; Miguel Viveiros; Rebeca Bailo; José A Aínsa
Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.
Sofia Santos Costa; Leonard Amaral; Miguel Viveiros; Isabel Couto
Multidrug Efflux Pumps in Staphylococcus aureus: an Update.

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2013: Sofia Costa; José Melo-Cristino; Cláudia Mourato; Miguel Viveiros; Leonard Amaral; Isabel Couto
Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain.
International journal of antimicrobial agents 2013;41(5):490-2.
2013: Liliana Rodrigues; Cristina Villellas; Miguel Viveiros; Rebeca Bailo; José A Aínsa
Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2013;57(2):751-7.
2013: Sofia Santos Costa; Leonard Amaral; Miguel Viveiros; Isabel Couto
Multidrug Efflux Pumps in Staphylococcus aureus: an Update.
The open microbiology journal 2013;7():59-71.
2013: João Perdigão; Carla Silva; Miguel Viveiros; Isabel Couto; Luisa Jordao; Rita Macedo; Diana Machado; Isabel Portugal
From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition.
The Journal of antimicrobial chemotherapy 2013;68(1):27-33.
2012: Bruno Veigas; Miguel Viveiros; Pedro Barquinha; Mafalda N Costa; Elvira Fortunato; João Inácio; Jorge M Jacob; Rodrigo Martins; David S Santos; Pedro Viana Baptista
Gold on paper-paper platform for Au-nanoprobe TB detection.
Lab on a chip 2012;12(22):4802-8.
2012: Miguel Viveiros; José Ainsa; Isabel Couto; Diana Machado; Marta Martins; Liliana Rodrigues; Leonard Amaral
Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.
Expert review of anti-infective therapy 2012;10(9):983-98.
2012: Liliana Rodrigues; Leonard Amaral; Isabel Couto; Diana Machado; Miguel Viveiros
Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2012;12(4):695-700.
2012: Leonard Amaral; Miguel Viveiros
Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections.
International journal of antimicrobial agents 2012;39(5):376-80.
2012: Anna Dymek; Jadwiga Handzlik; Joseph Molnar; Gabriella Spengler; Miguel Viveiros; Katarzyna Kiec-Kononowicz; Ana Armada; Leonard Amaral
The activity of 16 new hydantoin compounds on the intrinsic and overexpressed efflux pump system of Staphylococcus aureus.
In vivo (Athens, Greece) 2012;26(2):223-9.
2012: Diana Machado; João Perdigão; Isabel Portugal; Liliana Rodrigues; Bruno Veigas; Leonard Amaral; Pedro V Baptista; Isabel Couto; Miguel Viveiros
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
PloS one 2012;7(4):e34538.
2011: Gabriella Spengler; Miguel Viveiros; Jadwiga Handzlik; Katarzyna Kiec-Kononowicz; Joseph Molnar; Imre Ocsovszki; Leonard Amaral
Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.
Anticancer research 2011;31(10):3285-8.
2011: Lisa Machado; Joseph Molnár; Gabriella Spengler; Miguel Viveiros; Miguel Evaristo; Jadwiga Handzlik; Katarzyna Kiec-Kononowicz; Leonard Amaral
Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enterica serovar Enteritidis NCTC 13349.
In vivo (Athens, Greece) 2011;25(5):769-72.
2011: Daniella Takács; Miguel Viveiros; Pedro Cerca; Isabel Couto; György Hajós; Ana Martins; Joseph Molnár; Zsuzsanna Riedl; Leonard Amaral
Evaluation of forty new phenothiazine derivatives for activity against intrinsic efflux pump systems of reference Escherichia coli, Salmonella Enteritidis, Enterococcus faecalis and Staphylococcus aureus strains.
In vivo (Athens, Greece) 2011;25(5):719-24.
2011: Leonard Amaral; Pedro Cerca; Isabel Couto; Séamus Fanning; Lisa Machado; Ana Martins; Gabriella Spengler; Miguel Viveiros; Jean-Marie Pagès
Ethidium bromide efflux by Salmonella: modulation by metabolic energy, pH, ions and phenothiazines.
International journal of antimicrobial agents 2011;38(2):140-5.
2011: Pedro Cerca; Isabel Couto; Ana Martins; Miguel Viveiros; Leonard Amaral
Competition between substrates of the efflux pump system of Salmonella enteritidis.
In vivo (Athens, Greece) 2011;25(4):597-602.
2011: Leonard Amaral; Joseph Molnar; Miguel Viveiros; Jette E Kristiansen
Effective therapy with the neuroleptic thioridazine as an adjunct to second line of defence drugs, and the potential that thioridazine offers for new patents that cover a variety of "new uses".
Recent patents on anti-infective drug discovery 2011;6(2):84-7.
2011: Liliana Rodrigues; José A Aínsa; Leonard Amaral; Miguel Viveiros
Inhibition of drug efflux in mycobacteria with phenothiazines and other putative efflux inhibitors.
Recent patents on anti-infective drug discovery 2011;6(2):118-27.
2011: Mihail Lucian Pascu; Adriana Smarandache; Angela Staicu; Miguel Viveiros; Ionut Relu Andrei; Mihai Boni; Seamus Fanning; Ana Martins; Andra Militaru; Joseph Molnar; Viorel Nastasa; Alexandru Pascu; Leonard Amaral
Direct modification of bioactive phenothiazines by exposure to laser radiation.
Recent patents on anti-infective drug discovery 2011;6(2):147-57.
2011: Ana Martins; Lisa Machado; Susana Costa; Pedro Cerca; Gabriella Spengler; Miguel Viveiros; Leonard Amaral
Role of calcium in the efflux system of Escherichia coli.
International journal of antimicrobial agents 2011;37(5):410-4.
2011: Ana Martins; Andrea Vasas; Miguel Viveiros; Joseph Molnár; Judit Hohmann; Leonard Amaral
Antibacterial properties of compounds isolated from Carpobrotus edulis.
International journal of antimicrobial agents 2011;37(5):438-44.
2011: Marta Martins; Miguel Viveiros; Isabel Couto; Sofia Costa; Teresa Pacheco; Séamus Fanning; Jean-Marie Pagès; Leonard Amaral
Identification of efflux pump-mediated multidrug-resistant bacteria by the ethidium bromide-agar cartwheel method.
In vivo (Athens, Greece) 2011;25(2):171-8.
2011: Sofia Costa; Leonard Amaral; Celeste Falcão; Diana Machado; Marta Martins; José Melo-Cristino; Miguel Viveiros; Isabel Couto
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus.
BMC microbiology 2011;11():241.
2011: Liliana Rodrigues; Jorge Ramos; Isabel Couto; Leonard Amaral; Miguel Viveiros
Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.
BMC microbiology 2011;11():35.
2011: Cátia Ramalhete; Gabriella Spengler; Ana Martins; Marta Martins; Miguel Viveiros; Silva Mulhovo; Maria-José Umbelino Ferreira; Leonard Amaral
Inhibition of efflux pumps in methicillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina.
International journal of antimicrobial agents 2011;37(1):70-4.
2010: Gabriella Spengler; Miguel Evaristo; Jadwiga Handzlik; Julianna Serly; Joseph Molnár; Miguel Viveiros; Katarzyna Kiéc-Kononowicz; Leonard Amaral
Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells.
Anticancer research 2010;30(12):4867-71.
2010: Sofia Costa; Eleni Ntokou; Ana Martins; Miguel Viveiros; S Pournaras; Isabel Couto; Leonard Amaral
Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone.
International journal of antimicrobial agents 2010;36(6):557-61.
2010: Bruno Veigas; Diana Machado; João Perdigão; Isabel Portugal; Isabel Couto; Miguel Viveiros; Pedro V Baptista
Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.
Nanotechnology 2010;21(41):415101.
2010: Ana Martins; G Spengler; Marta Martins; L Rodrigues; Miguel Viveiros; Anne Davin-Regli; J Chevalier; Isabel Couto; Jean-Marie Pagès; Leonard Amaral
Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes.
International journal of antimicrobial agents 2010;36(4):313-8.
2010: Jette E Kristiansen; V F Thomsen; Ana Martins; Miguel Viveiros; Leonard Amaral
Non-antibiotics reverse resistance of bacteria to antibiotics.
In vivo (Athens, Greece) 2010;24(5):751-4.
2010: Jacqueline Chevalier; Abdallah Mahamoud; Milad Baitiche; Elissavet Adam; Miguel Viveiros; Adriana Smarandache; Andra Militaru; Mihail L Pascu; Leonard Amaral; Jean-Marie Pagès
Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains.
International journal of antimicrobial agents 2010;36(2):164-8.
2010: Isabel Couto; D Machado; Miguel Viveiros; L Rodrigues; Leonard Amaral
Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2010;16(8):1161-4.
2010: Leonard Amaral; Ana Martins; Joseph Molnar; Jette E Kristiansen; Marta Martins; Miguel Viveiros; Liliana Rodrigues; Gabriella Spengler; Isabel Couto; Jorge Ramos; Sujata G Dastidar; Séamus Fanning; Matt McCusker; Jean-Marie Pages
Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB.
In vivo (Athens, Greece) 2010;24(4):409-24.
2010: Miguel Viveiros; Marta Martins; Isabel Couto; Liliana Rodrigues; Diana Machado; Isabel Portugal; Leonard Amaral
Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.
Expert review of anti-infective therapy 2010;8(4):465-80.
2010: Ana Martins; A Vasas; Zsuzsanna Schelz; Miguel Viveiros; Joseph Molnár; Judit Hohmann; Leonard Amaral
Constituents of Carpobrotus edulis inhibit P-glycoprotein of MDR1-transfected mouse lymphoma cells.
Anticancer research 2010;30(3):829-35.
2010: Miguel Viveiros; Liliana Rodrigues; Marta Martins; Isabel Couto; Gabriella Spengler; Ana Martins; Leonard Amaral
Evaluation of efflux activity of bacteria by a semi-automated fluorometric system.
Methods in molecular biology (Clifton, N.J.) 2010;642():159-72.
2010: Marta Martins; Isabel Couto; Miguel Viveiros; Leonard Amaral
Identification of efflux-mediated multi-drug resistance in bacterial clinical isolates by two simple methods.
Methods in molecular biology (Clifton, N.J.) 2010;642():143-57.
2009: Liliana Rodrigues; Daniela Sampaio; Isabel Couto; Diana Machado; Winfried V Kern; Leonard Amaral; Miguel Viveiros
The role of efflux pumps in macrolide resistance in Mycobacterium avium complex.
International journal of antimicrobial agents 2009;34(6):529-33.
2009: Ana Martins; C Iversen; L Rodrigues; G Spengler; J Ramos; Winfried V Kern; Isabel Couto; Miguel Viveiros; Séamus Fanning; J M Pages; Leonard Amaral
An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators.
International journal of antimicrobial agents 2009;34(6):602-4.
2009: Gabriella Spengler; Cátia Ramalhete; Marta Martins; Ana Martins; Julianna Serly; Miguel Viveiros; Joseph Molnár; Noélia Duarte; Silva Mulhovo; Maria-José Umbelino Ferreira; Leonard Amaral
Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry.
Anticancer research 2009;29(10):3989-93.
2009: Gabriella Spengler; Miguel Viveiros; Marta Martins; Liliana Rodrigues; Ana Martins; Jozsef Molnar; Isabel Couto; Leonard Amaral
Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method.
Anticancer research 2009;29(6):2173-7.
2009: Marta Martins; Miguel Viveiros; Isabel Couto; Leonard Amaral
Targeting human macrophages for enhanced killing of intracellular XDR-TB and MDR-TB.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2009;13(5):569-73.
2009: Marta Martins; Miguel Viveiros; Jorge Ramos; Isabel Couto; Joseph Molnar; Martin Boeree; Leonard Amaral
SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB).
International journal of antimicrobial agents 2009;33(5):479-82.
2009: Laura Paixão; Liliana Rodrigues; Isabel Couto; Marta Martins; Pedro Fernandes; Carla C C R de Carvalho; Gabriel A Monteiro; Filipe Sansonetty; Leonard Amaral; Miguel Viveiros
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli.
Journal of biological engineering 2009;3():18.
2009: Ana Martins; Gabriella Spengler; Liliana Rodrigues; Miguel Viveiros; Jorge Ramos; Marta Martins; Isabel Couto; Séamus Fanning; Jean-Marie Pagès; Jean Michel Bolla; Joseph Molnar; Leonard Amaral
pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.
PloS one 2009;4(8):e6656.
2009: Gabriella Spengler; Ana Martins; Zsuzsanna Schelz; Liliana Rodrigues; Lone Aagaard; Marta Martins; Sofia Costa; Isabel Couto; Miguel Viveiros; Séamus Fanning; Jette E Kristiansen; Joseph Molnar; Leonard Amaral
Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method.
In vivo (Athens, Greece) 2009;23(1):81-7.
2008: Leonard Amaral; Marta Martins; Miguel Viveiros; Joseph Molnar; Jette E Kristiansen
Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps.
Current drug targets 2008;9(9):816-9.
2008: Miguel Viveiros; Marta Martins; Isabel Couto; L Rodrigues; G Spengler; Ana Martins; Jette E Kristiansen; Joseph Molnar; Leonard Amaral
New methods for the identification of efflux mediated MDR bacteria, genetic assessment of regulators and efflux pump constituents, characterization of efflux systems and screening for inhibitors of efflux pumps.
Current drug targets 2008;9(9):760-78.
2008: Isabel Couto; Sofia Costa; Miguel Viveiros; Marta Martins; Leonard Amaral
Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide.
The Journal of antimicrobial chemotherapy 2008;62(3):504-13.
2008: Miguel Viveiros; Ana Martins; Laura Paixão; Liliana Rodrigues; Marta Martins; Isabel Couto; Eva Fähnrich; Winfried V Kern; Leonard Amaral
Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method.
International journal of antimicrobial agents 2008;31(5):458-62.
2008: Liliana Rodrigues; Dirk Wagner; Miguel Viveiros; Daniela Sampaio; Isabel Couto; Martina Vavra; Winfried V Kern; Leonard Amaral
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis.
The Journal of antimicrobial chemotherapy 2008;61(5):1076-82.
2008: Marta Martins; Miguel Viveiros; Leonard Amaral
The TB laboratory of the future: macrophage-based selection of XDR-TB therapeutics.
Future microbiology 2008;3(2):135-44.
2008: Marta Martins; Sujata G Dastidar; Seamus Fanning; Jette E Kristiansen; Joseph Molnar; Jean-Marie Pagès; Zsuzsanna Schelz; Gabriella Spengler; Miguel Viveiros; Leonard Amaral
Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities.
International journal of antimicrobial agents 2008;31(3):198-208.
2008: Marta Martins; Miguel Viveiros; Leonard Amaral
Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M. tuberculosis by non-killing macrophages.
In vivo (Athens, Greece) 2008;22(1):69-75.
2007: Marta Martins; Miguel Viveiros; Jette E Kristiansen; Joseph Molnar; Leonard Amaral
The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis.
In vivo (Athens, Greece) 2007;21(5):771-5.
2007: Leonard Amaral; Marta Martins; Miguel Viveiros
Phenothiazines as anti-multi-drug resistant tubercular agents.
Infectious disorders drug targets 2007;7(3):257-65.
2007: Zsuzsanna Schelz; Marta Martins; Ana Martins; Miguel Viveiros; Joseph Molnar; Leonard Amaral
Elimination of plasmids by SILA compounds that inhibit efflux pumps of bacteria and cancer cells.
In vivo (Athens, Greece) 2007;21(4):635-9.
2007: Noélia Duarte; Maria-José Umbelino Ferreira; Marta Martins; Miguel Viveiros; Leonard Amaral
Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis: dependence upon system and medium employed.
Phytotherapy research : PTR 2007;21(7):601-4.
2007: Leonard Amaral; Marta Martins; Miguel Viveiros
Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps.
The Journal of antimicrobial chemotherapy 2007;59(6):1237-46.
2007: Leonard Amaral; Helga Engi; Miguel Viveiros; Joseph Molnar
Review. Comparison of multidrug resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents.
In vivo (Athens, Greece) 2007;21(2):237-44.
2007: Ana Martins; Isabel Couto; Lone Aagaard; Marta Martins; Miguel Viveiros; Jette E Kristiansen; Leonard Amaral
Prolonged exposure of methicillin-resistant Staphylococcus aureus (MRSA) COL strain to increasing concentrations of oxacillin results in a multidrug-resistant phenotype.
International journal of antimicrobial agents 2007;29(3):302-5.
2007: Marta Martins; Zsuzsanna Schelz; Ana Martins; Joseph Molnar; Gyorgy Hajös; Zsuzsanna Riedl; Miguel Viveiros; Ismail Yalcin; Esin Aki-Sener; Leonard Amaral
In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis.
International journal of antimicrobial agents 2007;29(3):338-40.
2007: Miguel Viveiros; Myrielle Dupont; Liliana Rodrigues; Isabel Couto; Anne Davin-Regli; Marta Martins; Jean-Marie Pagès; Leonard Amaral
Antibiotic stress, genetic response and altered permeability of E. coli.
PloS one 2007;2(4):e365.
2006: Marta Martins; Bruno Santos; Ana Martins; Miguel Viveiros; Isabel Couto; Alexandra Cruz; Jean-Marie Pagès; Joseph Molnar; Seamus Fanning; Leonard Amaral
An instrument-free method for the demonstration of efflux pump activity of bacteria.
In vivo (Athens, Greece) 2006;20(5):657-64.
2006: Leonard Amaral; Miguel Viveiros; Jette E Kristiansen
"Non-Antibiotics": alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries.
Current drug targets 2006;7(7):887-91.
2006: Krisztina Wolfart; Gabriella Spengler; Masami Kawase; Noboru Motohashi; Joseph Molnár; Miguel Viveiros; Leonard Amaral
Synergistic interaction between proton pump inhibitors and resistance modifiers: promoting effects of antibiotics and plasmid curing.
In vivo (Athens, Greece) 2006;20(3):367-72.
2006: Malthe M Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Joseph Molnar; Jette E Kristiansen; Leonard Amaral
Thioridazine reduces resistance of methicillin-resistant staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump.
In vivo (Athens, Greece) 2006;20(3):361-6.
2005: Miguel Viveiros; Clara Leandro; Liliana Rodrigues; Josefina Almeida; Rosário Bettencourt; Isabel Couto; Lurdes Carrilho; José Diogo; Ana Fonseca; Luís Lito; João Lopes; Teresa Pacheco; Mariana Pessanha; Judite Quirim; Luísa Sancho; Max Salfinger; Leonard Amaral
Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis.
Journal of clinical microbiology 2005;43(9):4880-4.
2005: Miguel Viveiros; Ana Jesus; Mafalda Brito; Clara Leandro; Marta Martins; Diane Ordway; Ana Maria Molnar; Joseph Molnar; Leonard Amaral
Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes.
Antimicrobial agents and chemotherapy 2005;49(8):3578-82.
2005: Miguel Viveiros; Marta Martins; Isabel Couto; Jette E Kristiansen; Joseph Molnar; Leonard Amaral
The in vitro activity of phenothiazines against Mycobacterium avium: potential of thioridazine for therapy of the co-infected AIDS patient.
In vivo (Athens, Greece) 2005;19(4):733-6.
2005: Diane Ordway; Luisa Pinto; Leonor Costa; Marta Martins; Clara Leandro; Miguel Viveiros; Leonard Amaral; Maria J Arroz; Fernando A Ventura; Hazel M Dockrell
Gamma delta T cell responses associated with the development of tuberculosis in health care workers.
FEMS immunology and medical microbiology 2005;43(3):339-50.
2005: Marta Martins; Diane Ordway; Malthe M Kristiansen; Miguel Viveiros; Clara Leandro; Joseph Molnar; Leonard Amaral
Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus.
Fitoterapia 2005;76(1):96-9.
2004: Marta Martins; Wilfrid Bleiss; Anorte Marko; Diane Ordway; Miguel Viveiros; Clara Leandro; Teresa Pacheco; Joseph Molnar; Jette E Kristiansen; Leonard Amaral
Clinical concentrations of thioridazine enhance the killing of intracellular methicillin-resistant Staphylococcus aureus: an in vivo, ex vivo and electron microscopy study.
In vivo (Athens, Greece) 2004;18(6):787-94.
2004: Leonard Amaral; Miguel Viveiros; Joseph Molnar
Antimicrobial activity of phenothiazines.
In vivo (Athens, Greece) 2004;18(6):725-31.
2003: Maria Amélia Grácio; António J dos Santos Grácio; Miguel Viveiros; Leonard Amaral
Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?
International journal of antimicrobial agents 2003;22(3):347-51.
2003: Miguel Viveiros; Clara Leandro; Leonard Amaral
Mycobacterial efflux pumps and chemotherapeutic implications.
International journal of antimicrobial agents 2003;22(3):274-8.
2003: Malthe M Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Jette E Kristiansen; Leonard Amaral
Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro.
International journal of antimicrobial agents 2003;22(3):250-3.
2003: Diane Ordway; Judit Hohmann; Miguel Viveiros; Antonio Viveiros; Joseph Molnar; Clara Leandro; Maria J Arroz; Maria Amelia Gracio; Leonard Amaral
Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S. aureus and promotes immune modulation.
Phytotherapy research : PTR 2003;17(5):512-9.
2003: Diane Ordway; Miguel Viveiros; Clara Leandro; Rosário Bettencourt; Josefina Almeida; Marta Martins; Jette E Kristiansen; Joseph Molnar; Leonard Amaral
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2003;47(3):917-22.
2002: Diane Ordway; Miguel Viveiros; Clara Leandro; Maria Jorge Arroz; Joseph Molnar; Jette E Kristiansen; Leonard Amaral
Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2002;8(3):227-31.
2002: Miguel Viveiros; Isabel Portugal; Rosário Bettencourt; Thomas C Victor; Annemarie M Jordaan; Clara Leandro; Diane Ordway; Leonard Amaral
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2002;46(9):2804-10.
2002: Diane Ordway; Miguel Viveiros; Clara Leandro; Maria J Arroz; Leonard Amaral
Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus.
International journal of antimicrobial agents 2002;20(1):34-43.
2001: Leonard Amaral; Miguel Viveiros; Jette E Kristiansen
Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries.
Tropical medicine & international health : TM & IH 2001;6(12):1016-22.
2001: Leonard Amaral; Jette E Kristiansen; Miguel Viveiros; J Atouguia
Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.
The Journal of antimicrobial chemotherapy 2001;47(5):505-11.
2001: Miguel Viveiros; Leonard Amaral
Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines.
International journal of antimicrobial agents 2001;17(3):225-8.
2000: Miguel Viveiros; Philipp Krubasik; Gerhard Sandmann; M Houssaini-Iraqui
Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+.
FEMS microbiology letters 2000;187(1):95-101.
1999: Miguel Viveiros; S Pinheiro; Patrícia Moreira; Teresa Pacheco; Laura Brum
Evaluation of a commercial ligase chain reaction assay for the diagnosis of pulmonary and extra-pulmonary tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;3(6):508-14.
1999: Isabel Portugal; M J Covas; Laura Brum; Miguel Viveiros; P Ferrinho; José Moniz-Pereira; H David
Outbreak of multiple drug-resistant tuberculosis in Lisbon: detection by restriction fragment length polymorphism analysis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;3(3):207-13.
1997: G Ribeiro; Miguel Viveiros; H L David; JV Costa
Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5.
Microbiology (Reading, England) 1997;143 ( Pt 8)():2701-8.