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FX Hubert

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Lymphocyte Culture Test, Mixed

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Thomas Anjubault; Camille Chauvin; Dominique Heymann; FX Hubert; Jérôme Martin; Régis Josien
Constitutive expression of TNF-related activation-induced cytokine (TRANCE)/receptor activating NF-κB ligand (RANK)-L by rat plasmacytoid dendritic cells.
FX Hubert; Sarah A Kinkel; Adrian Liston; Scott N Mueller; Belinda Phipson; Anna I Proietto; Hamish Scott; Gordon K Smyth; Li Wu; Ping Z F Cannon; Francis R Carbone; Gayle M Davey; Simon Forehan; Christopher C Goodnow; William R Heath
Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.
Hyun-Ja Ko; Sarah A Kinkel; FX Hubert; Zeyad Nasa; James Chan; Christopher Siatskas; Premila Hirubalan; Ban-Hock Toh; Hamish Scott; Frank Alderuccio
Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis.

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2012: Thomas Anjubault; Camille Chauvin; Dominique Heymann; FX Hubert; Jérôme Martin; Régis Josien
Constitutive expression of TNF-related activation-induced cytokine (TRANCE)/receptor activating NF-κB ligand (RANK)-L by rat plasmacytoid dendritic cells.
PloS one 2012;7(3):e33713.
2011: FX Hubert; Sarah A Kinkel; Adrian Liston; Scott N Mueller; Belinda Phipson; Anna I Proietto; Hamish Scott; Gordon K Smyth; Li Wu; Ping Z F Cannon; Francis R Carbone; Gayle M Davey; Simon Forehan; Christopher C Goodnow; William R Heath
Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.
Blood 2011;118(9):2462-72.
2010: Hyun-Ja Ko; Sarah A Kinkel; FX Hubert; Zeyad Nasa; James Chan; Christopher Siatskas; Premila Hirubalan; Ban-Hock Toh; Hamish Scott; Frank Alderuccio
Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis.
European journal of immunology 2010;40(12):3499-509.
2010: Katherine Kedzierska; Sophie A Valkenburg; Carole Guillonneau; FX Hubert; Tania Cukalac; Joan M Curtis; John Stambas; Hamish Scott; Lukasz Kedzierski; Vanessa Venturi; Miles P Davenport
Diversity and clonotypic composition of influenza-specific CD8+ TCR repertoires remain unaltered in the absence of Aire.
European journal of immunology 2010;40(3):849-58.
2009: Ian K Campbell; Sarah A Kinkel; Sarah F Drake; Annemarie van Nieuwenhuijze; FX Hubert; David M Tarlinton; William R Heath; Hamish Scott; Ian P Wicks
Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis.
Arthritis and rheumatism 2009;60(6):1683-93.
2009: FX Hubert; Sarah A Kinkel; Pauline E Crewther; Ping Z F Cannon; Kylie E Webster; Maire Link; Raivo Uibo; Moira K O'Bryan; Anthony Meager; Simon P Forehan; Gordon K Smyth; Lauréane Mittaz; Stylianos E Antonarakis; Pärt Peterson; William R Heath; Hamish Scott
Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3902-18.
2009: Carole Guillonneau; Justine D Mintern; FX Hubert; Aeron C Hurt; Gurdyal S Besra; Steven A Porcelli; Ian Barr; Peter C Doherty; Dale I Godfrey; Stephen J Turner
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3330-5.
2008: Camille Chauvin; Jean-Marie Philippeau; Caroline Hémont; FX Hubert; Yohann Wittrant; François Lamoureux; Benjamin Trinité; Dominique Heymann; Françoise Rédini; Régis Josien
Killer dendritic cells link innate and adaptive immunity against established osteosarcoma in rats.
Cancer research 2008;68(22):9433-40.
2008: Lauren A Pitt; FX Hubert; Hamish Scott; Dale I Godfrey; Stuart P Berzins
NKT cell development in the absence of the autoimmune regulator gene (Aire).
European journal of immunology 2008;38(10):2689-96.
2008: Magali Irla; Stéphanie Hugues; Jason Gill; Takeshi Nitta; Yu Hikosaka; Ifor Williams; FX Hubert; Hamish Scott; Yousuke Takahama; Georg A Holländer; Walter Reith
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.
Immunity 2008;29(3):451-63.
2008: Asmahan Ouabed; FX Hubert; Dominique Chabannes; Laetitia Gautreau; Michèle Heslan; Régis Josien
Differential control of T regulatory cell proliferation and suppressive activity by mature plasmacytoid versus conventional spleen dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(9):5862-70.
2008: FX Hubert; Sarah A Kinkel; Kylie E Webster; Ping Cannon; Pauline E Crewther; Anna I Proeitto; Li Wu; William R Heath; Hamish Scott
A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):3824-32.
2007: Marcelo Hill; Séverine Tanguy-Royer; Pierre-Joseph Royer; Christine Chauveau; Kashif Asghar; Laurent Tesson; Frédéric Lavainne; Séverine Rémy; Régis Brion; FX Hubert; Michèle Heslan; Marie Rimbert; Laureline Berthelot; John R Moffett; Régis Josien; Marc Grégoire; Ignacio Anegon
IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cells.
European journal of immunology 2007;37(11):3054-62.
2007: Carole Guillonneau; Marcelo Hill; FX Hubert; Elise Chiffoleau; Caroline Hervé; Xian-Liang Li; Michèle Heslan; Claire Usal; Laurent Tesson; Séverine Ménoret; Abdelhadi Saoudi; Brigitte Le Mauff; Régis Josien; Maria Cristina Cuturi; Ignacio Anegon
CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase.
The Journal of clinical investigation 2007;117(4):1096-106.
2006: FX Hubert; Cécile Voisine; Cédric Louvet; Jean-Marie Heslan; Asmahan Ouabed; Michèle Heslan; Régis Josien
Differential pattern recognition receptor expression but stereotyped responsiveness in rat spleen dendritic cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1007-16.
2006: Nicolas Degauque; David LAIR; Alexandre Dupont; Anne Moreau; Gwénaelle Roussey; Frédérique Moizant; FX Hubert; Cédric Louvet; Marcelo Hill; Fabienne Haspot; Régis Josien; Claire Usal; Bernard Vanhove; Jean-Paul Soulillou; Sophie Brouard
Dominant tolerance to kidney allografts induced by anti-donor MHC class II antibodies: cooperation between T and non-T CD103+ cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):3915-22.
2006: James F Curtin; Gwendalyn D King; Carlos Barcia; Chunyan Liu; FX Hubert; Carole Guillonneau; Régis Josien; Ignacio Anegon; Pedro R Lowenstein; Maria G Castro
Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3566-77.
2005: Christine Chauveau; Séverine Rémy; Pierre-Joseph Royer; Marcelo Hill; Séverine Tanguy-Royer; FX Hubert; Laurent Tesson; Régis Brion; Gaëlle Beriou; Marc Gregoire; Régis Josien; Maria Cristina Cuturi; Ignacio Anegon
Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression.
Blood 2005;106(5):1694-702.
2004: FX Hubert; Cécile Voisine; Cédric Louvet; Michèle Heslan; Régis Josien
Rat plasmacytoid dendritic cells are an abundant subset of MHC class II+ CD4+CD11b-OX62- and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7485-94.
2002: Cécile Voisine; FX Hubert; Benjamin Trinité; Michèle Heslan; Régis Josien
Two phenotypically distinct subsets of spleen dendritic cells in rats exhibit different cytokine production and T cell stimulatory activity.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2284-91.