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Rolf Issels
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15
Multhoff, Gabriele
12
Wilmanns, W
12
Botzler, C
11
Abdel-Rahman, Sultan
11
Lindner, Lars
9
Noessner, Elfriede
9
Schlemmer, Marcus
8
Reiser, Maximilian
8
Peller, Michael
8
Wendtner, Clemens-Martin
7
Hiddemann, Wolfgang
6
Kuppner, Maria
6
Milani, Valeria
4
Falk, MH
4
Eibl, Hansjörg
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All Publications
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2009: Jarius Sven; Arnold Stephan; Linke Rainer; Noachtar Soheyl; Schlemmer Marcus; Issels Rolf; Voltz Raymond
Long term survival in anti-Hu associated adult neuroblastoma.
Journal of the neurological sciences 2009;284(1-2):205-8.
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2009: Le Cesne Axel; Van Glabbeke Martine; Verweij Jaap; Casali Paolo G; Findlay Michael; Reichardt Peter; Issels Rolf; Judson Ian; Schoffski Patrick; Leyvraz Serge; Bui Binh; Hogendoorn Pancras C W; Sciot Raf; Blay Jean-Yves
Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(24):3969-74.
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2009: Stahl Robert; Wang Tungte; Lindner Lars H; Abdel-Rahman Sultan; Santl Margareta; Reiser Maximilian F; Issels Rolf D
Comparison of radiological and pathohistological response to neoadjuvant chemotherapy combined with regional hyperthermia (RHT) and study of response dependence on the applied thermal parameters in patients with soft tissue sarcomas (STS).
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2009;25(4):289-98.
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2009: Milani Valeria; Lorenz Monika; Weinkauf Marc; Rieken Malte; Pastore Alessandro; Dreyling Martin; Issels Rolf
Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2009;25(4):262-72.
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2009: Pandya Maya J; Bendz Henriette; Manzenrieder Florian; Noessner Elfriede; Kessler Horst; Buchner Johannes; Issels Rolf D
Interaction of human heat shock protein 70 with tumor-associated peptides.
Biological chemistry 2009;390(4):305-12.
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2009: Milani Valeria; Stangl Stefan; Issels Rolf; Gehrmann Mathias; Wagner Beate; Hube Kathrin; Mayr Doris; Hiddemann Wolfgang; Molls Michael; Multhoff Gabriele
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report.
Journal of translational medicine 2009;7():50.
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2008: Bleifuss Elke; Bendz Henriette; Sirch Birgit; Thompson Sylvia; Brandl Anna; Milani Valeria; Graner Michael W; Drexler Ingo; Kuppner Maria; Katsanis Emmanuel; Noessner Elfriede; Issels Rolf-Dieter
Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(8):623-37.
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2008: Schwerdt Alenka; Zintchenko Arkadi; Concia Massimo; Roesen Nick; Fisher Kerry; Lindner Lars H; Issels Rolf; Wagner Ernst; Ogris Manfred
Hyperthermia-induced targeting of thermosensitive gene carriers to tumors.
Human gene therapy 2008;19(11):1283-92.
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2008: Issels Rolf D
Hyperthermia adds to chemotherapy.
European journal of cancer (Oxford, England : 1990) 2008;44(17):2546-54.
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2008: Bendz Henriette; Marincek Boris-Christian; Momburg Frank; Ellwart Joachim W; Issels Rolf D; Nelson Peter J; Noessner Elfriede
Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation.
The Journal of biological chemistry 2008;283(39):26477-83.
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2008: Kuppner M C; Bleifuss E; Noessner E; Mocikat R; Hesler C von; Mayerhofer C; Issels R D
Differential effects of ifosfamide on dendritic cell-mediated stimulation of T cell interleukin-2 production, natural killer cell cytotoxicity and interferon-gamma production.
Clinical and experimental immunology 2008;153(3):429-38.
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2008: Cho C H; Wust P; Hildebrandt B; Issels R D; Sehouli J; Kerner T; Deja M; Budach V; Gellermann J
Regional hyperthermia of the abdomen in conjunction with chemotherapy for peritoneal carcinomatosis: evaluation of two annular-phased-array applicators.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(5):399-408.
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2008: Issels Rolf D
Regional hyperthermia in high-risk soft tissue sarcomas.
Current opinion in oncology 2008;20(4):438-43.
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2008: Milani Valeria; Pazos Montserrat; Issels Rolf Dieter; Buecklein Veit; Rahman Sultan; Tschoep Katharina; Schaffer Pamela; Wilkowski Ralf; Duehmke Eckhart; Schaffer Moshe
Radiochemotherapy in combination with regional hyperthermia in preirradiated patients with recurrent rectal cancer.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2008;184(3):163-8.
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2008: Banjac A; Perisic T; Sato H; Seiler A; Bannai S; Weiss N; Kölle P; Tschoep K; Issels R D; Daniel P T; Conrad M; Bornkamm G W
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.
Oncogene 2008;27(11):1618-28.
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2008: Wang Tungte; Hossann Martin; Reinl Herbert M; Peller Michael; Eibl Hansjoerg; Reiser Maximilian; Issels Rolf D; Lindner Lars H
In vitro characterization of phosphatidylglyceroglycerol-based thermosensitive liposomes with encapsulated 1H MR T1-shortening gadodiamide.
Contrast media & molecular imaging 2008;3(1):19-26.
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2008: Lindner Lars H; Hossann Martin; Vogeser Michael; Teichert Nicole; Wachholz Kirsten; Eibl Hansjoerg; Hiddemann Wolfgang; Issels Rolf D
Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release.
Journal of controlled release : official journal of the Controlled Release Society 2008;125(2):112-20.
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2007: Bendz Henriette; Ruhland Sibylle C; Pandya Maya J; Hainzl Otmar; Riegelsberger Stefan; Braüchle Christoph; Mayer Matthias P; Buchner Johannes; Issels Rolf D; Noessner Elfriede
Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling.
The Journal of biological chemistry 2007;282(43):31688-702.
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2007: Hossann Martin; Wiggenhorn Michael; Schwerdt Alenka; Wachholz Kirsten; Teichert Nicole; Eibl Hansjörg; Issels Rolf D; Lindner Lars H
In vitro stability and content release properties of phosphatidylglyceroglycerol containing thermosensitive liposomes.
Biochimica et biophysica acta 2007;1768(10):2491-9.
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2007: Pfister Karin; Radons Jürgen; Busch Raymonde; Tidball James G; Pfeifer Michael; Freitag Lutz; Feldmann Horst-Jürgen; Milani Valeria; Issels Rolf; Multhoff Gabriele
Patient survival by Hsp70 membrane phenotype: association with different routes of metastasis.
Cancer 2007;110(4):926-35.
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2007: Tschoep Katharina; Kohlmann Alexander; Schlemmer Marcus; Haferlach Torsten; Issels Rolf-Dieter
Gene expression profiling in sarcomas.
Critical reviews in oncology/hematology 2007;63(2):111-24.
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2007: Verweij Jaap; Casali Paolo G; Kotasek Dusan; Le Cesne Axel; Reichard Peter; Judson Ian R; Issels R; van Oosterom Allan T; Van Glabbeke Martine; Blay Jean-Yves
Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: analysis of EORTC-ISG-AGITG study 62005.
European journal of cancer (Oxford, England : 1990) 2007;43(6):974-8.
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2007: Boeck Stefan; Wilkowski Ralf; Bruns Christiane J; Issels Rolf D; Schulz Christoph; Moosmann Nicolas; Laessig Dorit; Haas Michael; Golf Alexander; Heinemann Volker
Oral capecitabine in gemcitabine-pretreated patients with advanced pancreatic cancer.
Oncology 2007;73(3-4):221-7.
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2006: Bischoff J; Lindner L H; Issels R D; Costa S
[Clinical impact of locoregional hyperthermia in gynecological oncology]
Zentralblatt für Gynäkologie 2006;128(5):255-60.
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2006: Gellermann Johanna; Hildebrandt Bert; Issels Rolf; Ganter Hildegard; Wlodarczyk Waldemar; Budach Volker; Felix Roland; Tunn Per-Ulf; Reichardt Peter; Wust Peter
Noninvasive magnetic resonance thermography of soft tissue sarcomas during regional hyperthermia: correlation with response and direct thermometry.
Cancer 2006;107(6):1373-82.
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2006: Van Glabbeke Martine; Verweij Jaap; Casali Paolo G; Simes John; Le Cesne Axel; Reichardt Peter; Issels Rolf; Judson Ian R; van Oosterom Allan T; Blay Jean-Yves
Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: a study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Trials Group (EORTC-ISG-AGITG).
European journal of cancer (Oxford, England : 1990) 2006;42(14):2277-85.
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2006: Issels Rolf D; Schlemmer Marcus; Lindner Lars H
The role of hyperthermia in combined treatment in the management of soft tissue sarcoma.
Current oncology reports 2006;8(4):305-9.
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2006: Issels Rolf D
High-risk soft tissue sarcoma: clinical trial and hyperthermia combined chemotherapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(3):235-9.
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2006: Schlemmer Marcus; Wendtner Clemens-Martin; Falk Martin; Abdel-Rahman Sultan; Licht Thomas; Baumert Jens; Straka Christian; Hentrich Marcus; Salat Christoph; Hiddemann Wolfgang; Issels Rolf-Dieter
Efficacy of consolidation high-dose chemotherapy with ifosfamide, carboplatin and etoposide (HD-ICE) followed by autologous peripheral blood stem cell rescue in chemosensitive patients with metastatic soft tissue sarcomas.
Oncology 2006;71(1-2):32-9.
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2005: Reinl Herbert M; Peller Michael; Hagmann Mark; Turner Paul; Issels Rolf D; Reiser Maximilian
Ferrite-enhanced MRI monitoring in hyperthermia.
Magnetic resonance imaging 2005;23(10):1017-20.
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2005: Milani Valeria; Frankenberger Bernhard; Heinz Oksana; Brandl Anna; Ruhland Sibylle; Issels Rolf Dieter; Noessner Elfriede
Melanoma-associated antigen tyrosinase but not Melan-A/MART-1 expression and presentation dissociate during the heat shock response.
International immunology 2005;17(3):257-68.
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2004: Fahn Werner; Issels Rolf D
Emerging treatments for soft tissue sarcoma of adults.
Expert opinion on emerging drugs 2004;9(2):313-34.
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2004: Verweij Jaap; Casali Paolo G; Zalcberg John; LeCesne Axel; Reichardt Peter; Blay Jean-Yves; Issels Rolf; van Oosterom Allan; Hogendoorn Pancras C W; Van Glabbeke Martine; Bertulli Rossella; Judson Ian
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial.
Lancet 2004;364(9440):1127-34.
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2004: Fiegl M; Schlemmer M; Wendtner C-M; Abdel-Rahman S; Fahn W; Issels R D
Ifosfamide, carboplatin and etoposide (ICE) as second-line regimen alone and in combination with regional hyperthermia is active in chemo-pre-treated advanced soft tissue sarcoma of adults.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2004;20(6):661-70.
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2004: Peller M; Muacevic A; Reinl H; Sroka R; Abdel-Rahman S; Issels R; Reiser M F
[MRI-assisted thermometry for regional hyperthermia and interstitial laser thermotherapy]
Der Radiologe 2004;44(4):310-9.
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2004: Schlemmer M; Lindner L H; Abdel-Rahman S; Issels R D
[Principles, technology and indication of hyperthermia and part body hyperthermia]
Der Radiologe 2004;44(4):301-9.
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2004: Lindner Lars H; Eichhorn Martin E; Eibl Hansjoerg; Teichert Nicole; Schmitt-Sody Marcus; Issels Rolf D; Dellian Marc
Novel temperature-sensitive liposomes with prolonged circulation time.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(6):2168-78.
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2004: Milani V; Endres M; Kuppner M C; Issels R D; Noessner E
[Heat shock proteins, immune competence and vaccination]
Deutsche medizinische Wochenschrift (1946) 2004;129(1-2):31-5.
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2003: Reichardt Peter; Oechsle Karin; Pink Daniel; Bokemeyer Carsten; Schneller F; Issels Rolf; Kanz Lothar; Hartmann Jörg Thomas
An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.
Investigational new drugs 2003;21(4):481-6.
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2003: Kuppner Maria C; Scharner Anabel; Milani Valeria; Von Hesler Christoph; Tschop Katharina E; Heinz Oksana; Issels Rolf D
Ifosfamide impairs the allostimulatory capacity of human dendritic cells by intracellular glutathione depletion.
Blood 2003;102(10):3668-74.
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2003: Tschoep K; Kohlmann A; Schlemmer M; Haferlach T; Issels R
[Gene expression analysis using DNA microarrays in soft tissue and bone tumors]
Deutsche medizinische Wochenschrift (1946) 2003;128(39):2030-6.
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2003: Wust P; Hegewisch-Becker S; Issels R
[Hyperthermia: current status and therapeutic results]
Deutsche medizinische Wochenschrift (1946) 2003;128(39):2023-9.
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2003: Lindner L H; Issels R
[Thermosensitive liposomes for regional hyperthermia]
Deutsche medizinische Wochenschrift (1946) 2003;128(39):2020-2.
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2003: Fahn W; Schlemmer M; Issels R; Uberfuhr P; Reichart B
[Leiomyosarcoma of the heart--interdisciplinary therapeutic approach of systemic chemotherapy and subsequent heart transplantation]
Deutsche medizinische Wochenschrift (1946) 2003;128(39):2005-8.
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2003: Baur A; Stäbler A; Wendtner C M; Arbogast S; Rahman S A; Santl M; Issels R; Reiser M
MR-imaging changes of musculoskeletal soft-tissue sarcomas associated with neoadjuvant chemotherapy and hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(4):391-401.
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2003: Peller Michael; Kurze Volker; Loeffler Ralf; Pahernik Sascha; Dellian Marc; Goetz Alwin E; Issels Rolf; Reiser Maximilian
Hyperthermia induces T1 relaxation and blood flow changes in tumors. A MRI thermometry study in vivo.
Magnetic resonance imaging 2003;21(5):545-51.
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2003: Schaffer M; Krych M; Pachmann S; Abdel-Rahman S; Schaffer P M; Ertl-Wagner B; D hmke E; Issels R D
Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer--preliminary results.
Onkologie 2003;26(2):120-4.
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2003: Schlemmer M; Wendtner C M; Issels R D
Ifosfamide with regional hyperthermia in soft-tissue sarcomas.
Oncology 2003;65 Suppl 2():76-9.
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2002: Milani V; Noessner E; Ghose S; Kuppner M; Ahrens B; Scharner A; Gastpar R; Issels R D
Heat shock protein 70: role in antigen presentation and immune stimulation.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002;18(6):563-75.
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2002: Repasky Elizabeth; Issels Rolf
Physiological consequences of hyperthermia: heat, heat shock proteins and the immune response.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002;18(6):486-9.
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2002: Noessner Elfriede; Gastpar Robert; Milani Valeria; Brandl Anna; Hutzler Peter J S; Kuppner Maria C; Roos Miriam; Kremmer Elisabeth; Asea Alexzander; Calderwood Stuart K; Issels Rolf D
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5424-32.
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2002: Uberfuhr Peter; Meiser Bruno; Fuchs Alexandra; Schulze Costas; Reichenspurner Hermann; Falk Martin; Weiss Max; Wintersperger Bernd; Issels Rolf; Reichart Bruno
Heart transplantation: an approach to treating primary cardiac sarcoma?
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2002;21(10):1135-9.
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2002: Wendtner Clemens-M; Abdel-Rahman Sultan; Krych Matthäus; Baumert Jens; Lindner Lars H; Baur Andrea; Hiddemann Wolfgang; Issels Rolf D
Response to neoadjuvant chemotherapy combined with regional hyperthermia predicts long-term survival for adult patients with retroperitoneal and visceral high-risk soft tissue sarcomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(14):3156-64.
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2002: Peller Michael; Reinl Herbert M; Weigel Andreas; Meininger Martin; Issels Rolf D; Reiser Maximilian
T1 relaxation time at 0.2 Tesla for monitoring regional hyperthermia: feasibility study in muscle and adipose tissue.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(6):1194-201.
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2002: Issels R D; Schlemmer M
Current trials and new aspects in soft tissue sarcoma of adults.
Cancer chemotherapy and pharmacology 2002;49 Suppl 1():S4-8.
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2002: Vabulas Ramunas M; Ahmad-Nejad Parviz; Ghose Sanghamitra; Kirschning Carsten J; Issels Rolf D; Wagner Hermann
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway.
The Journal of biological chemistry 2002;277(17):15107-12.
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2001: Wendtner C; Abdel-Rahman S; Baumert J; Falk M H; Krych M; Santl M; Hiddemann W; Issels R D
Treatment of primary, recurrent or inadequately resected high-risk soft-tissue sarcomas (STS) of adults: results of a phase II pilot study (RHT-95) of neoadjuvant chemotherapy combined with regional hyperthermia.
European journal of cancer (Oxford, England : 1990) 2001;37(13):1609-16.
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2001: Issels R D; Abdel-Rahman S; Wendtner C; Falk M H; Kurze V; Sauer H; Aydemir U; Hiddemann W
Neoadjuvant chemotherapy combined with regional hyperthermia (RHT) for locally advanced primary or recurrent high-risk adult soft-tissue sarcomas (STS) of adults: long-term results of a phase II study.
European journal of cancer (Oxford, England : 1990) 2001;37(13):1599-608.
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2001: Kuppner M C; Gastpar R; Gelwer S; Nössner E; Ochmann O; Scharner A; Issels R D
The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors.
European journal of immunology 2001;31(5):1602-9.
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2001: Falk M H; Issels R D
Hyperthermia in oncology.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2001;17(1):1-18.
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1999: Wendtner C M; Abdel-Rahman S; Issels R D
[Regional and whole-body hyperthermia]
Deutsche medizinische Wochenschrift (1946) 1999;124(46):1398-9.
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1999: Wessalowski R; Van Heek-Romanowski R; Issels R D; Jürgens H T; Göbel U
Estimated number of children with cancer eligible for hyperthermia based on population- and treatment-related criteria.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(6):455-66.
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1999: Pahernik S A; Peller M; Dellian M; Loeffler R; Issels R; Reiser M; Messmer K; Goetz A E
Validation of MR thermometry technology: a small animal model for hyperthermic treatment of tumours.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1999;199(2):59-71.
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1999: Peller M; Löffler R; Baur A; Turner P; Abdel-Rahman S; Futschik G; Santl M; Hiddemann W; Reiser M; Issels R
[MRI-controlled regional hyperthermia]
Der Radiologe 1999;39(9):756-63.
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1998: Botzler C; Schmidt J; Luz A; Jennen L; Issels R; Multhoff G
Differential Hsp70 plasma-membrane expression on primary human tumors and metastases in mice with severe combined immunodeficiency.
International journal of cancer. Journal international du cancer 1998;77(6):942-8.
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1998: Bertsch F; Mattner J; Stehling M K; Müller-Lisse U; Peller M; Loeffler R; Weber J; Messmer K; Wilmanns W; Issels R; Reiser M
Non-invasive temperature mapping using MRI: comparison of two methods based on chemical shift and T1-relaxation.
Magnetic resonance imaging 1998;16(4):393-404.
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1998: Botzler C; Li G; Issels R D; Multhoff G
Definition of extracellular localized epitopes of Hsp70 involved in an NK immune response.
Cell stress & chaperones 1998;3(1):6-11.
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1998: Multhoff G; Botzler C; Issels R
The role of heat shock proteins in the stimulation of an immune response.
Biological chemistry 1998;379(3):295-300.
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1998: Falk M H; Meier T; Issels R D; Brielmeier M; Scheffer B; Bornkamm G W
Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake.
International journal of cancer. Journal international du cancer 1998;75(4):620-5.
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1998: Heinemann V; Schulz L; Issels R D; Wilmanns W
Regulation of deoxycytidine kinase by deoxycytidine and deoxycytidine 5' triphosphate in whole leukemia and tumor cells.
Advances in experimental medicine and biology 1998;431():249-53.
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1997: Multhoff G; Botzler C; Jennen L; Schmidt J; Ellwart J; Issels R
Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4341-50.
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1997: Botzler C; Kis K; Issels R; Multhoff G
A comparison of the effects of ifosfamide vs. mafosfamide treatment on intracellular glutathione levels and immunological functions of immunocompetent lymphocyte subsets.
Experimental hematology 1997;25(4):338-44.
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1996: Botzler C; Issels R; Multhoff G
Heat-shock protein 72 cell-surface expression on human lung carcinoma cells in associated with an increased sensitivity to lysis mediated by adherent natural killer cells.
Cancer immunology, immunotherapy : CII 1996;43(4):226-30.
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1996: Multhoff G; Botzler C; Allenbacher A; Issels R
Effects of ifosfamide on immunocompetent effector cells.
Cancer immunology, immunotherapy : CII 1996;42(4):251-4.
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1996: Botzler C; Kolb H J; Issels R D; Multhoff G
Noncytotoxic alkyl-lysophospholipid treatment increases sensitivity of leukemic K562 cells to lysis by natural killer (NK) cells.
International journal of cancer. Journal international du cancer 1996;65(5):633-8.
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1995: Wust P; Fähling H; Felix R; Rahman S; Issels R D; Feldmann H; van Rhoon G; van der Zee J
Quality control of the SIGMA applicator using a lamp phantom: a four-centre comparison.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1995;11(6):755-67; discussion 867, 869.
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1995: Issels R D
Soft tissue sarcomas--what is currently being done.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1995;21(5):471-4.
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1995: Meier T; Issels R D
Degradation of 2-(3-aminopropylamino)-ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of Chinese hamster ovary cells.
Biochemical pharmacology 1995;50(4):489-96.
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1995: Multhoff G; Botzler C; Wiesnet M; Eissner G; Issels R
CD3- large granular lymphocytes recognize a heat-inducible immunogenic determinant associated with the 72-kD heat shock protein on human sarcoma cells.
Blood 1995;86(4):1374-82.
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1995: Heinemann V; Schulz L; Issels R D; Plunkett W
Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism.
Seminars in oncology 1995;22(4 Suppl 11):11-8.
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1995: Multhoff G; Meier T; Botzler C; Wiesnet M; Allenbacher A; Wilmanns W; Issels R D
Differential effects of ifosfamide on the capacity of cytotoxic T lymphocytes and natural killer cells to lyse their target cells correlate with intracellular glutathione levels.
Blood 1995;85(8):2124-31.
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1995: Multhoff G; Botzler C; Wiesnet M; Müller E; Meier T; Wilmanns W; Issels R D
A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells.
International journal of cancer. Journal international du cancer 1995;61(2):272-9.
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1995: Issels R D
Regional hyperthermia combined with systemic chemotherapy of locally advanced sarcomas: preclinical aspects and clinical results.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1995;138():81-90.
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1995: Meier T; Issels R D
Promotion of cyst(e)ine uptake.
Methods in enzymology 1995;252():103-12.
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1994: Meier T; Allenbacher A; Mueller E; Multhoff G; Botzler C; Wiesnet M; Issels R
Ifosfamide induced depletion of glutathione in human peripheral blood lymphocytes and protection by mesna.
Anti-cancer drugs 1994;5(4):403-9.
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1994: Fuller K J; Issels R D; Slosman D O; Guillet J G; Soussi T; Polla B S
Cancer and the heat shock response.
European journal of cancer (Oxford, England : 1990) 1994;30A(12):1884-91.
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1993: Issels R D; Bosse D; Starck M; Abdel-Rahman S; Jauch K W; Schildberg F W; Wilmanns W
[Soft tissue tumors: indications and results of hyperthermia]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1993;64(6):461-7.
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1993: Kampinga H H; Muller E; Brunsting J F; Heine L; Konings A W; Issels R D
Association of HSP72 with the nuclear (TX-100-insoluble) fraction upon heating tolerant and non-tolerant HeLa S3 cells.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1993;9(1):89-98.
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1993: Issels R D; Bosse D; Abdel-Rahman S; Starck M; Panzer M; Jauch K W; Stiegler H; Berger H; Sauer H; Peter K
Preoperative systemic etoposide/ifosfamide/doxorubicin chemotherapy combined with regional hyperthermia in high-risk sarcoma: a pilot study.
Cancer chemotherapy and pharmacology 1993;31 Suppl 2():S233-7.
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1993: Issels R D; Meier T H; Müller E; Multhoff G; Wilmanns W
Ifosfamide induced stress response in human lymphocytes.
Molecular aspects of medicine 1993;14(3):281-6.
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1993: Issels R D
Hyperthermia and thermochemotherapy.
Cancer treatment and research 1993;67():143-60.
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1992: Issels R D
[Antioxidants]
Der Internist 1992;33(2):122.
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1991: Issels R D; Mittermüller J; Gerl A; Simon W; Ortmaier A; Denzlinger C; Sauer H; Wilmanns W
Improvement of local control by regional hyperthermia combined with systemic chemotherapy (ifosfamide plus etoposide) in advanced sarcomas: updated report on 65 patients.
Journal of cancer research and clinical oncology 1991;117 Suppl 4():S141-7.
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1990: Issels R D; Prenninger S W; Nagele A; Boehm E; Sauer H; Jauch K W; Denecke H; Berger H; Peter K; Wilmanns W
Ifosfamide plus etoposide combined with regional hyperthermia in patients with locally advanced sarcomas: a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1990;8(11):1818-29.
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1990: Issels R D; Nagele A
Influence of thiols on thermosensitivity of mammalian cells in vitro.
Methods in enzymology 1990;186():696-708.
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1989: Issels R D; Nagele A
Promotion of cystine uptake, increase of glutathione biosynthesis, and modulation of glutathione status by S-2-(3-aminopropylamino)ethyl phosphorothioic acid (WR-2721) in Chinese hamster cells.
Cancer research 1989;49(8):2082-6.
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1989: Issels R; Wadepohl M; Cramer H; Krieger K; Wilmanns W
[Hyperthermia in cancer research. Historical development, current status of research, future perspectives and differentiation from alternative medical procedures]
Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V 1989;41(2):48-53.
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1988: Issels R; Krieger K
[Status of regional hyperthermia. Combination with systemic chemotherapy in malignant tumors of the pelvis]
Fortschritte der Medizin 1988;106(21):437-8.
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1988: Issels R D; Nagele A; Eckert K G; Wilmanns W
Promotion of cystine uptake and its utilization for glutathione biosynthesis induced by cysteamine and N-acetylcysteine.
Biochemical pharmacology 1988;37(5):881-8.
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1988: Berger H; Markl G; Issels R D; Lissner J
Percutaneous placement of catheters for temperature measurement during hyperthermia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;107():263-6.
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1988: Issels R D; Wadepohl M; Tiling K; Müller M; Sauer H; Wilmanns W
Regional hyperthermia combined with systemic chemotherapy in advanced abdominal and pelvic tumors: first results of a pilot study employing an annular phased array applicator.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;107():236-43.
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1988: Issels R D
Sulfhydryl compounds as thermosensitizers.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;109():22-7.
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1987: Issels R D; Nagele A; Böning B; Bourier S; Wilmanns W
Thiol-compounds as thermosensitizer: experimental results.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1987;163(7):420-1.
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1987: Issels R D; Bourier S; Böning B; Li G C; Mak J J; Wilmanns W
Influence of oxidative stress induced by cysteamine upon the induction and development of thermotolerance in Chinese hamster ovary cells.
Cancer research 1987;47(9):2268-74.
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1986: Issels R D; Fink R M; Lengfelder E
Effects of hyperthermic conditions on the reactivity of oxygen radicals.
Free radical research communications 1986;2(1-2):7-18.
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1985: Issels R D; Bourier S; Biaglow J E; Gerweck L E; Wilmanns W
Temperature-dependent influence of thiols upon glutathione levels in Chinese hamster ovary cells at cytotoxic concentrations.
Cancer research 1985;45(12 Pt 1):6219-24.
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1984: Issels R D; Biaglow J E; Epstein L; Gerweck L E
Enhancement of cysteamine cytotoxicity by hyperthermia and its modification by catalase and superoxide dismutase in Chinese hamster ovary cells.
Cancer research 1984;44(9):3911-5.
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