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FRANK BALIS

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Kim A; Gillespie A; Dombi E; Goodwin A; Goodspeed W; Fox E; Balis F M; Widemann B C
Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas.
Abraham Jame; Edgerly Maureen; Wilson Richard; Chen Clara; Rutt Ann; Bakke Susan; Robey Rob; Dwyer Andrew; Goldspiel Barry; Balis Frank; Van Tellingen Olaf; Bates Susan E; Fojo Tito
A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine.
Balis F M; Fox E; Widemann B C; Adamson P C
Clinical drug development for childhood cancers.

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All Publications

2009: Kim A; Gillespie A; Dombi E; Goodwin A; Goodspeed W; Fox E; Balis F M; Widemann B C
Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas.
Neurology 2009;73(16):1273-9.
2009: Abraham Jame; Edgerly Maureen; Wilson Richard; Chen Clara; Rutt Ann; Bakke Susan; Robey Rob; Dwyer Andrew; Goldspiel Barry; Balis Frank; Van Tellingen Olaf; Bates Susan E; Fojo Tito
A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3574-82.
2009: Balis F M; Fox E; Widemann B C; Adamson P C
Clinical drug development for childhood cancers.
Clinical pharmacology and therapeutics 2009;85(2):127-9.
2009: Widemann Brigitte C; Goodspeed Wendy; Goodwin Anne; Fojo Tito; Balis Frank M; Fox Elizabeth
Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(4):550-6.
2008: Warren Katherine E; McCully Cindy; Dvinge Henrik; Tjørnelund Jette; Sehested Maxwell; Lichenstein Henri S; Balis Frank M
Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.
Cancer chemotherapy and pharmacology 2008;62(3):433-7.
2008: Meany Holly J; Fox Elizabeth; McCully Cynthia; Tucker Chris; Balis Frank M
The plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite (OSI-420) after intravenous administration of erlotinib in non-human primates.
Cancer chemotherapy and pharmacology 2008;62(3):387-92.
2008: Bernardi Ronald J; Bomgaars Lisa; Fox Elizabeth; Balis Frank M; Egorin Merrill J; Lagattuta Theodore F; Aikin Alberta; Whitcomb Patricia; Renbarger Jamie; Lieberman Frank S; Berg Stacey L; Blaney Susan M
Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis.
Cancer chemotherapy and pharmacology 2008;62(2):355-61.
2008: Kim Aerang; Fox Elizabeth; Warren Katherine; Blaney Susan M; Berg Stacey L; Adamson Peter C; Libucha Madeleine; Byrley Elena; Balis Frank M; Widemann Brigitte C
Characteristics and outcome of pediatric patients enrolled in phase I oncology trials.
The oncologist 2008;13(6):679-89.
2008: Fox Elizabeth; Maris John M; Widemann Brigitte C; Goodspeed Wendy; Goodwin Anne; Kromplewski Marie; Fouts Molly E; Medina Diane; Cohn Susan L; Krivoshik Andrew; Hagey Anne E; Adamson Peter C; Balis Frank M
A phase I study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 21 days every 28 days in pediatric patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1111-5.
2008: Fox Elizabeth; Razzouk Bassem I; Widemann Brigitte C; Xiao Shaun; O'Brien Michelle; Goodspeed Wendy; Reaman Gregory H; Blaney Susan M; Murgo Anthony J; Balis Frank M; Adamson Peter C
Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma.
Blood 2008;111(2):566-73.
2007: Adamson Peter C; Matthay Katherine K; O'Brien Michelle; Reaman Gregory H; Sato Judith K; Balis Frank M
A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch, NCI and Children's Oncology Group Study.
Pediatric blood & cancer 2007;49(5):661-5.
2007: Cho Steve Y; Fox Elizabeth; McCully Cynthia; Bauch Joy; Marsh Kennan; Balis Frank M
Plasma and cerebrospinal fluid pharmacokinetics of intravenously administered ABT-751 in non-human primates.
Cancer chemotherapy and pharmacology 2007;60(4):563-7.
2007: Jacobs Shana S; Stork Linda C; Bostrom Bruce C; Hutchinson Ray; Holcenberg John; Reaman Gregory H; Erdmann Gary; Franklin Janet; Neglia Joseph P; Steinberg Seth M; Balis Frank M; Adamson Peter C;
Substitution of oral and intravenous thioguanine for mercaptopurine in a treatment regimen for children with standard risk acute lymphoblastic leukemia: a collaborative Children's Oncology Group/National Cancer Institute pilot trial (CCG-1942).
Pediatric blood & cancer 2007;49(3):250-5.
2007: Dombi E; Solomon J; Gillespie A J; Fox E; Balis F M; Patronas N; Korf B R; Babovic-Vuksanovic D; Packer R J; Belasco J; Goldman S; Jakacki R; Kieran M; Steinberg S M; Widemann B C
NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.
Neurology 2007;68(9):643-7.
2006: Nathan Paul C; Whitcomb Trish; Wolters Pamela L; Steinberg Seth M; Balis Frank M; Brouwers Pim; Hunsberger Sally; Feusner James; Sather Harland; Miser James; Odom Lorrie F; Poplack David; Reaman Gregory; Bleyer W Archie
Very high-dose methotrexate (33.6 g/m(2)) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children's Cancer Group trials CCG-191P, CCG-134P and CCG-144P.
Leukemia & lymphoma 2006;47(12):2488-504.
2006: Warren K; Jakacki R; Widemann B; Aikin A; Libucha M; Packer R; Vezina G; Reaman G; Shaw D; Krailo M; Osborne C; Cehelsky J; Caldwell D; Stanwood J; Steinberg S M; Balis F M
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group.
Cancer chemotherapy and pharmacology 2006;58(3):343-7.
2006: Fox Elizabeth; Maris John M; Widemann Brigitte C; Meek Kysa; Goodwin Anne; Goodspeed Wendy; Kromplewski Marie; Fouts Molly E; Medina Diane; Cho Steve Y; Cohn Susan L; Krivoshik Andrew; Hagey Anne E; Adamson Peter C; Balis Frank M
A phase 1 study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 7 days every 21 days in pediatric patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4882-7.
2006: Widemann Brigitte C; Salzer Wanda L; Arceci Robert J; Blaney Susan M; Fox Elizabeth; End David; Gillespie Andrea; Whitcomb Patricia; Palumbo Joseph S; Pitney Aaron; Jayaprakash Nalini; Zannikos Peter; Balis Frank M
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(3):507-16.
2005: Hazra Rohan; Gafni Rachel I; Maldarelli Frank; Balis Frank M; Tullio Antonella N; DeCarlo Ellen; Worrell Carol J; Steinberg Seth M; Flaherty John; Yale Kitty; Kearney Brian P; Zeichner Steven L
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infection.
Pediatrics 2005;116(6):e846-54.
2005: Warren Katherine E; Aikin Alberta A; Libucha Madeleine; Widemann Brigitte C; Fox Elizabeth; Packer Roger J; Balis Frank M
Phase I study of O6-benzylguanine and temozolomide administered daily for 5 days to pediatric patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7646-53.
2005: Rao V Koneti; Knutsen Turid; Ried Thomas; Wangsa Darawalee; Flynn Bernard Mike; Langham Gregory; Egorin Merrill J; Cole Diane; Balis Frank; Steinberg Seth M; Bates Susan; Fojo Tito
The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration.
Mutation research 2005;583(2):105-19.
2005: Zhuang Sen H; Agrawal Manish; Edgerly Maureen; Bakke Susan; Kotz Herb; Thambi Paul; Rutt Ann; Balis Frank M; Bates Susan; Fojo Tito
A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days.
Cancer 2005;103(9):1932-8.
2005: Blaney Susan M; Balis Frank M; Berg Stacey; Arndt Carola A S; Heideman Richard; Geyer J Russell; Packer Roger; Adamson Peter C; Jaeckle Kurt; Klenke Renee; Aikin Alberta; Murphy Robert; McCully Cynthia; Poplack David G
Intrathecal mafosfamide: a preclinical pharmacology and phase I trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(7):1555-63.
2005: Jacobs Shana S; Fox Elizabeth; Dennie Christopher; Morgan Lindsey B; McCully Cynthia L; Balis Frank M
Plasma and cerebrospinal fluid pharmacokinetics of intravenous oxaliplatin, cisplatin, and carboplatin in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1669-74.
2005: Lebowitz Peter F; Eng-Wong Jennifer; Widemann Brigitte C; Balis Frank M; Jayaprakash Nalini; Chow Catherine; Clark Geoff; Gantz Susan B; Venzon David; Zujewski JoAnne
A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1247-52.
2004: Widemann Brigitte C; Balis Frank M; Shalabi Aiman; Boron Matthew; O'Brien Michelle; Cole Diane E; Jayaprakash Nalini; Ivy Percy; Castle Valerie; Muraszko Karin; Moertel Christopher L; Trueworthy Robert; Hermann Robert C; Moussa Ali; Hinton Stuart; Reaman Gregory; Poplack David; Adamson Peter C
Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.
Journal of the National Cancer Institute 2004;96(20):1557-9.
2004: Warren Katherine; Gervais Anne; Aikin Alberta; Egorin Merrill; Balis Frank M
Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors.
Cancer chemotherapy and pharmacology 2004;54(3):206-12.
2004: Wolfraim Lawrence A; Fernandez Tania M; Mamura Mizuko; Fuller Walter L; Kumar Rajesh; Cole Diane E; Byfield Stacey; Felici Angelina; Flanders Kathleen C; Walz Thomas M; Roberts Anita B; Aplan Peter D; Balis Frank M; Letterio John J
Loss of Smad3 in acute T-cell lymphoblastic leukemia.
The New England journal of medicine 2004;351(6):552-9.
2004: Bates Susan E; Bakke Susan; Kang Min; Robey Robert W; Zhai Suoping; Thambi Paul; Chen Clara C; Patil Sheela; Smith Tom; Steinberg Seth M; Merino Maria; Goldspiel Barry; Meadows Beverly; Stein Wilfred D; Choyke Peter; Balis Frank; Figg William D; Fojo Tito
A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4724-33.
2004: Adamson P C; Blaney S M; Widemann B C; Kitchen B; Murphy R F; Hannah A L; Cropp G F; Patel M; Gillespie A F; Whitcomb P G; Balis F M
Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101.
Cancer chemotherapy and pharmacology 2004;53(6):482-8.
2004: Widemann Brigitte C; Balis Frank M; Kempf-Bielack Beate; Bielack Stefan; Pratt Charles B; Ferrari Stefano; Bacci Gaetano; Craft Alan W; Adamson Peter C
High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma.
Cancer 2004;100(10):2222-32.
2004: Neville Kathleen; Parise Robert A; Thompson Patrick; Aleksic Alexander; Egorin Merrill J; Balis Frank M; McGuffey Leticia; McCully Cynthia; Berg Stacey L; Blaney Susan M
Plasma and cerebrospinal fluid pharmacokinetics of imatinib after administration to nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2525-9.
2004: Hazra Rohan; Balis Frank M; Tullio Antonella N; DeCarlo Ellen; Worrell Carol J; Steinberg Seth M; Flaherty John F; Yale Kitty; Poblenz Marianne; Kearney Brian P; Zhong Lijie; Coakley Dion F; Blanche Stephane; Bresson Jean Louis; Zuckerman Judith A; Zeichner Steven L
Single-dose and steady-state pharmacokinetics of tenofovir disoproxil fumarate in human immunodeficiency virus-infected children.
Antimicrobial agents and chemotherapy 2004;48(1):124-9.
2004: Hawkins Mary E; Balis Frank M
Use of pteridine nucleoside analogs as hybridization probes.
Nucleic acids research 2004;32(7):e62.
2003: Thompson Patrick; Balis Frank; Serabe Baruti M; Berg Stacey; Adamson Peter; Klenke Renee; Aiken Alberta; Packer Roger; Murry Daryl J; Jakacki Regina; Blaney Susan M
Pharmacokinetics of phenylacetate administered as a 30-min infusion in children with refractory cancer.
Cancer chemotherapy and pharmacology 2003;52(5):417-23.
2003: Salzer Wanda; Steinberg Seth M; Liewehr David J; Freifeld Alison; Balis Frank M; Widemann Brigitte C
Evaluation and treatment of fever in the non-neutropenic child with cancer.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2003;25(8):606-12.
2003: Abraham Jame; Agrawal Manish; Bakke Susan; Rutt Ann; Edgerly Maureen; Balis Frank M; Widemann Brigitte; Davis Louis; Damle Bharat; Sonnichsen Daryl; Lebwohl David; Bates Susan; Kotz Herb; Fojo Tito
Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(9):1866-73.
2003: Patel Mahendra; McCully Cynthia; Godwin Karen; Balis Frank M
Plasma and cerebrospinal fluid pharmacokinetics of intravenous temozolomide in non-human primates.
Journal of neuro-oncology 2003;61(3):203-7.
2003: Agrawal Manish; Abraham Jame; Balis Frank M; Edgerly Maureen; Stein Wilfred D; Bates Susan; Fojo Tito; Chen Clara C
Increased 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):650-6.
2003: Blaney Susan M; Heideman Richard; Berg Stacey; Adamson Peter; Gillespie Andy; Geyer J Russell; Packer Roger; Matthay Kate; Jaeckle Kurt; Cole Diane; Kuttesch Nancy; Poplack David G; Balis Frank M
Phase I clinical trial of intrathecal topotecan in patients with neoplastic meningitis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(1):143-7.
2002: Egorin Merrill J; Zuhowski Eleanor G; McCully Cynthia M; Blaney Susan M; Kerr Jody Z; Berg Stacey L; Balis Frank M
Pharmacokinetics of intrathecal gemcitabine in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2437-42.
2002: Lutz Robert J; Warren Kathy; Balis Frank; Patronas Nicholas; Dedrick Robert L
Mixing during intravertebral arterial infusions in an in vitro model.
Journal of neuro-oncology 2002;58(2):95-106.
2002: Fox Elizabeth; Bungay Peter M; Bacher John; McCully Cynthia L; Dedrick Robert L; Balis Frank M
Zidovudine concentration in brain extracellular fluid measured by microdialysis: steady-state and transient results in rhesus monkey.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1003-11.
2002: Wilson Wyndham H; Grossbard Michael L; Pittaluga Stefania; Cole Diane; Pearson Deborah; Drbohlav Nicole; Steinberg Seth M; Little Richard F; Janik John; Gutierrez Martin; Raffeld Mark; Staudt Louis; Cheson Bruce D; Longo Dan L; Harris Nancy; Jaffe Elaine S; Chabner Bruce A; Wittes Robert; Balis Frank
Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy.
Blood 2002;99(8):2685-93.
2002: Balis Frank M
Evolution of anticancer drug discovery and the role of cell-based screening.
Journal of the National Cancer Institute 2002;94(2):78-9.
2002: Fox Elizabeth; Curt Gregory A; Balis Frank M
Clinical trial design for target-based therapy.
The oncologist 2002;7(5):401-9.
2001: Hawkins M E; Pfleiderer W; Jungmann O; Balis F M
Synthesis and fluorescence characterization of pteridine adenosine nucleoside analogs for DNA incorporation.
Analytical biochemistry 2001;298(2):231-40.
2001: Warren K E; Patel M C; Aikin A A; Widemann B; Libucha M; Adamson P C; Neuwirth R; Benziger D; O'Toole T; Ford K; Patronas N; Packer R J; Balis F M
Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors.
Cancer chemotherapy and pharmacology 2001;48(4):275-82.
2001: Adamson P C; Widemann B C; Reaman G H; Seibel N L; Murphy R F; Gillespie A F; Balis F M
A phase I trial and pharmacokinetic study of 9-cis-retinoic acid (ALRT1057) in pediatric patients with refractory cancer: a joint Pediatric Oncology Branch, National Cancer Institute, and Children's Cancer Group study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3034-9.
2001: Salzer W; Widemann B; McCully C; Adamson P C; Balis F M
Effect of probenecid on ventricular cerebrospinal fluid methotrexate pharmacokinetics after intralumbar administration in nonhuman primates.
Cancer chemotherapy and pharmacology 2001;48(3):235-40.
2001: Warren K E; Patronas N; Aikin A A; Albert P S; Balis F M
Comparison of one-, two-, and three-dimensional measurements of childhood brain tumors.
Journal of the National Cancer Institute 2001;93(18):1401-5.
2001: Bungay P M; Dedrick R L; Fox E; Balis F M
Probe calibration in transient microdialysis in vivo.
Pharmaceutical research 2001;18(3):361-6.
2001: Lowe E S; Kitchen B J; Erdmann G; Stork L C; Bostrom B C; Hutchinson R; Holcenberg J; Reaman G H; Woods W; Franklin J; Widemann B C; Balis F M; Murphy R F; Adamson P C
Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study.
Cancer chemotherapy and pharmacology 2001;47(3):199-205.
2001: Grem J L; Quinn M; Ismail A S; Takimoto C H; Lush R; Liewehr D J; Steinberg S M; Balis F M; Chen A P; Monahan B P; Harold N; Corse W; Pang J; Murphy R F; Allegra C J; Hamilton J M
Pharmacokinetics and pharmacodynamic effects of 5-fluorouracil given as a one-hour intravenous infusion.
Cancer chemotherapy and pharmacology 2001;47(2):117-25.
2000: Kinsella T J; Schupp J E; Davis T W; Berry S E; Hwang H S; Warren K; Balis F; Barnett J; Sands H
Preclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3670-9.
2000: Long L; Berg S L; Roy S K; McCully C L; Song-Yoo H W; Moschel R C; Balis F M; Dolan M E
Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3662-9.
2000: Widemann B C; Sung E; Anderson L; Salzer W L; Balis F M; Monitjo K S; McCully C; Hawkins M; Adamson P C
Pharmacokinetics and metabolism of the methotrexate metabolite 2, 4-diamino-N(10)-methylpteroic acid.
The Journal of pharmacology and experimental therapeutics 2000;294(3):894-901.
2000: Moser A M; Patel M; Yoo H; Balis F M; Hawkins M E
Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.
Analytical biochemistry 2000;281(2):216-22.
2000: Warren K E; McCully C M; Walsh T J; Balis F M
Effect of fluconazole on the pharmacokinetics of doxorubicin in nonhuman primates.
Antimicrobial agents and chemotherapy 2000;44(4):1100-1.
2000: Warren K E; Frank J A; Black J L; Hill R S; Duyn J H; Aikin A A; Lewis B K; Adamson P C; Balis F M
Proton magnetic resonance spectroscopic imaging in children with recurrent primary brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(5):1020-6.
2000: Wilson W H; Sorbara L; Figg W D; Mont E K; Sausville E; Warren K E; Balis F M; Bauer K; Raffeld M; Senderowicz A M; Monks A
Modulation of clinical drug resistance in a B cell lymphoma patient by the protein kinase inhibitor 7-hydroxystaurosporine: presentation of a novel therapeutic paradigm.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):415-21.
2000: Balis F M
Clinical trials in childhood cancers.
The oncologist 2000;5(3):xii-xiii.
2000: Balis F M; Blaney S M; McCully C L; Bacher J D; Murphy R F; Poplack D G
Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration.
Cancer chemotherapy and pharmacology 2000;45(3):259-64.
2000: Warren K E; Patel M C; McCully C M; Montuenga L M; Balis F M
Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates.
Cancer chemotherapy and pharmacology 2000;45(3):207-12.
1999: Balis F M; Adamson P C
Application of pharmacogenetics to optimization of mercaptopurine dosing.
Journal of the National Cancer Institute 1999;91(23):1983-5.
1999: Kitchen B J; Moser A; Lowe E; Balis F M; Widemann B; Anderson L; Strong J; Blaney S M; Berg S L; O'Brien M; Adamson P C
Thioguanine administered as a continuous intravenous infusion to pediatric patients is metabolized to the novel metabolite 8-hydroxy-thioguanine.
The Journal of pharmacology and experimental therapeutics 1999;291(2):870-4.
1999: Roth J S; McCully C M; Balis F M; Poplack D G; Kelley J A
2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(10):1128-32.
1999: Seibel N L; Blaney S M; O'Brien M; Krailo M; Hutchinson R; Mosher R B; Balis F M; Reaman G H
Phase I trial of docetaxel with filgrastim support in pediatric patients with refractory solid tumors: a collaborative Pediatric Oncology Branch, National Cancer Institute and Children's Cancer Group trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):733-7.
1999: Callender D P; Jayaprakash N; Bell A; Petraitis V; Petraitiene R; Candelario M; Schaufele R; Dunn J M; Sei S; Walsh T J; Balis F M;
Pharmacokinetics of oral zidovudine entrapped in biodegradable nanospheres in rabbits.
Antimicrobial agents and chemotherapy 1999;43(4):972-4.
1999: Widemann B C; Balis F M; Adamson P C
Dihydrofolate reductase enzyme inhibition assay for plasma methotrexate determination using a 96-well microplate reader.
Clinical chemistry 1999;45(2):223-8.
1999: Berg S L; Reid J; Godwin K; Murry D J; Poplack D G; Balis F M; Ames M M
Pharmacokinetics and cerebrospinal fluid penetration of daunorubicin, idarubicin, and their metabolites in the nonhuman primate model.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 1999;21(1):26-30.
1999: Moser A M; Adamson P C; Gillespie A J; Poplack D G; Balis F M
Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma.
Cancer 1999;85(2):511-6.
1999: Widemann B C; Balis F M; Godwin K S; McCully C; Adamson P C
The plasma pharmacokinetics and cerebrospinal fluid penetration of the thymidylate synthase inhibitor raltitrexed (Tomudex) in a nonhuman primate model.
Cancer chemotherapy and pharmacology 1999;44(6):439-43.
1998: Mueller B U; Lewis L L; Yuen G J; Farley M; Keller A; Church J A; Goldsmith J C; Venzon D J; Rubin M; Pizzo P A; Balis F M
Serum and cerebrospinal fluid pharmacokinetics of intravenous and oral lamivudine in human immunodeficiency virus-infected children.
Antimicrobial agents and chemotherapy 1998;42(12):3187-92.
1998: Berg S L; Murry D J; McCully C L; Godwin K; Balis F M
Pharmacokinetics of O6-benzylguanine and its active metabolite 8-oxo-O6-benzylguanine in plasma and cerebrospinal fluid after intrathecal administration of O6-benzylguanine in the nonhuman primate.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2891-4.
1998: Balis F M; Holcenberg J S; Poplack D G; Ge J; Sather H N; Murphy R F; Ames M M; Waskerwitz M J; Tubergen D G; Zimm S; Gilchrist G S; Bleyer W A
Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study.
Blood 1998;92(10):3569-77.
1998: Mueller B U; Anderson B D; Farley M Q; Murphy R; Zuckerman J; Jarosinski P; Godwin K; McCully C L; Mitsuya H; Pizzo P A; Balis F M
Pharmacokinetics of the protease inhibitor KNI-272 in plasma and cerebrospinal fluid in nonhuman primates after intravenous dosing and in human immunodeficiency virus-infected children after intravenous and oral dosing.
Antimicrobial agents and chemotherapy 1998;42(7):1815-8.
1998: Mueller B U; Sleasman J; Nelson R P; Smith S; Deutsch P J; Ju W; Steinberg S M; Balis F M; Jarosinski P F; Brouwers P; Mistry G; Winchell G; Zwerski S; Sei S; Wood L V; Zeichner S; Pizzo P A
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
Pediatrics 1998;102(1 Pt 1):101-9.
1998: Mueller B U; Nelson R P; Sleasman J; Zuckerman J; Heath-Chiozzi M; Steinberg S M; Balis F M; Brouwers P; Hsu A; Saulis R; Sei S; Wood L V; Zeichner S; Katz T T; Higham C; Aker D; Edgerly M; Jarosinski P; Serchuck L; Whitcup S M; Pizzuti D; Pizzo P A
A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.
Pediatrics 1998;101(3 Pt 1):335-43.
1998: Blaney S M; Needle M N; Gillespie A; Sato J K; Reaman G H; Berg S L; Adamson P C; Krailo M D; Bleyer W A; Poplack D G; Balis F M
Phase II trial of topotecan administered as 72-hour continuous infusion in children with refractory solid tumors: a collaborative Pediatric Branch, National Cancer Institute, and Children's Cancer Group Study.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):357-60.
1998: Berg S L; Blaney S M; Adamson P C; O'Brien M; Poplack D G; Arndt C; Blatt J; Balis F M
Phase I trial and pharmacokinetic study of pyrazoloacridine in children and young adults with refractory cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(1):181-6.
1998: Blaney S M; Takimoto C; Murry D J; Kuttesch N; McCully C; Cole D E; Godwin K; Balis F M
Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates.
Cancer chemotherapy and pharmacology 1998;41(6):464-8.
1997: Driscoll S L; Hawkins M E; Balis F M; Pfleiderer W; Laws W R
Fluorescence properties of a new guanosine analog incorporated into small oligonucleotides.
Biophysical journal 1997;73(6):3277-86.
1997: Adamson P C; Reaman G; Finklestein J Z; Feusner J; Berg S L; Blaney S M; O'Brien M; Murphy R F; Balis F M
Phase I trial and pharmacokinetic study of all-trans-retinoic acid administered on an intermittent schedule in combination with interferon-alpha2a in pediatric patients with refractory cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(11):3330-7.
1997: Grem J L; McAtee N; Murphy R F; Balis F M; Cullen E; Chen A P; Hamilton J M; Steinberg S M; Quinn M; Sorensen J M; Arbuck S G; Lawrence D; Pang J; Allegra C J
A pilot study of gamma-1b-interferon in combination with fluorouracil, leucovorin, and alpha-2a-interferon.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1125-34.
1997: Kitchen B J; Balis F M; Poplack D G; O'Brien M; Craig C E; Adamson P C
A pediatric phase I trial and pharmacokinetic study of thioguanine administered by continuous i.v. infusion.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):713-7.
1997: Widemann B C; Balis F M; Murphy R F; Sorensen J M; Montello M J; O'Brien M; Adamson P C
Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):2125-34.
1997: Blaney S M; Seibel N L; O'Brien M; Reaman G H; Berg S L; Adamson P C; Poplack D G; Krailo M D; Mosher R; Balis F M
Phase I trial of docetaxel administered as a 1-hour infusion in children with refractory solid tumors: a collaborative pediatric branch, National Cancer Institute and Children's Cancer Group trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(4):1538-43.
1997: Hawkins M E; Pfleiderer W; Balis F M; Porter D; Knutson J R
Fluorescence properties of pteridine nucleoside analogs as monomers and incorporated into oligonucleotides.
Analytical biochemistry 1997;244(1):86-95.
1996: Wexler L H; DeLaney T F; Tsokos M; Avila N; Steinberg S M; Weaver-McClure L; Jacobson J; Jarosinski P; Hijazi Y M; Balis F M; Horowitz M E
Ifosfamide and etoposide plus vincristine, doxorubicin, and cyclophosphamide for newly diagnosed Ewing's sarcoma family of tumors.
Cancer 1996;78(4):901-11.
1996: Blaney S M; Phillips P C; Packer R J; Heideman R L; Berg S L; Adamson P C; Allen J C; Sallan S E; Jakacki R I; Lange B J; Reaman G H; Horowitz M E; Poplack D G; Balis F M
Phase II evaluation of topotecan for pediatric central nervous system tumors.
Cancer 1996;78(3):527-31.
1996: Lewis L L; Venzon D; Church J; Farley M; Wheeler S; Keller A; Rubin M; Yuen G; Mueller B; Sloas M; Wood L; Balis F; Shearer G M; Brouwers P; Goldsmith J; Pizzo P A
Lamivudine in children with human immunodeficiency virus infection: a phase I/II study. The National Cancer Institute Pediatric Branch-Human Immunodeficiency Virus Working Group.
The Journal of infectious diseases 1996;174(1):16-25.
1996: Grem J L; Politi P M; Berg S L; Benchekroun N M; Patel M; Balis F M; Sinha B K; Dahut W; Allegra C J
Cytotoxicity and DNA damage associated with pyrazoloacridine in MCF-7 breast cancer cells.
Biochemical pharmacology 1996;51(12):1649-59.
1996: Tolcher A W; Cowan K H; Solomon D; Ognibene F; Goldspiel B; Chang R; Noone M H; Denicoff A M; Barnes C S; Gossard M R; Fetsch P A; Berg S L; Balis F M; Venzon D J; O'Shaughnessy J A
Phase I crossover study of paclitaxel with r-verapamil in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(4):1173-84.
1996: Fisherman J S; Cowan K H; Noone M; Denicoff A; Berg S; Poplack D; Balis F; Venzon D; McCabe M; Goldspiel B; Chow C; Ognibene F P; O'Shaughnessy J
Phase I/II study of 72-hour infusional paclitaxel and doxorubicin with granulocyte colony-stimulating factor in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(3):774-82.
1996: Wexler L H; Andrich M P; Venzon D; Berg S L; Weaver-McClure L; Chen C C; Dilsizian V; Avila N; Jarosinski P; Balis F M; Poplack D G; Horowitz M E
Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(2):362-72.
1996: Geyer J R; Balis F M; Krailo M D; Heideman R; Broxson E; Sato J K; Poplack D; Bleyer W A
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
Investigational new drugs 1996;13(4):337-42.
1995: Ho P T; Zimmerman K; Wexler L H; Blaney S; Jarosinski P; Weaver-McClure L; Izraeli S; Balis F M
A prospective evaluation of ifosfamide-related nephrotoxicity in children and young adults.
Cancer 1995;76(12):2557-64.
1995: Blaney S M; Daniel M J; Harker A J; Godwin K; Balis F M
Pharmacokinetics of lamivudine and BCH-189 in plasma and cerebrospinal fluid of nonhuman primates.
Antimicrobial agents and chemotherapy 1995;39(12):2779-82.
1995: Berg S L; Gerson S L; Godwin K; Cole D E; Liu L; Balis F M
Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate.
Cancer research 1995;55(20):4606-10.
1995: Adamson P C; Balis F M; Belasco J E; Lange B; Berg S L; Blaney S M; Craig C; Poplack D G
A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer.
Cancer research 1995;55(18):4069-72.
1995: Widemann B C; Hetherington M L; Murphy R F; Balis F M; Adamson P C
Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity.
Cancer 1995;76(3):521-6.
1995: Hawkins M E; Pfleiderer W; Mazumder A; Pommier Y G; Balis F M
Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction.
Nucleic acids research 1995;23(15):2872-80.
1995: Berg S L; Tolcher A; O'Shaughnessy J A; Denicoff A M; Noone M; Ognibene F P; Cowan K H; Balis F M
Effect of R-verapamil on the pharmacokinetics of paclitaxel in women with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(8):2039-42.
1995: Wilson W H; Jamis-Dow C; Bryant G; Balis F M; Klecker R W; Bates S E; Chabner B A; Steinberg S M; Kohler D R; Wittes R E
Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(8):1985-94.
1995: Hawkins M E; Mitsuya H; McCully C M; Godwin K S; Murakami K; Poplack D G; Balis F M
Pharmacokinetics of dideoxypurine nucleoside analogs in plasma and cerebrospinal fluid of rhesus monkeys.
Antimicrobial agents and chemotherapy 1995;39(6):1259-64.
1995: Adamson P C; Bailey J; Pluda J; Poplack D G; Bauza S; Murphy R F; Yarchoan R; Balis F M
Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(5):1238-41.
1995: Smith R A; Balis F M; Ott K H; Elsberry D D; Sherman M R; Saifer M G
Pharmacokinetics and tolerability of ventricularly administered superoxide dismutase in monkeys and preliminary clinical observations in familial ALS.
Journal of the neurological sciences 1995;129 Suppl():13-8.
1995: Godwin K S; McCully C L; Poplack D C; Balis F M
An animal facility database management system using a Macintosh computer and commercially available software.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 1995;34(2):54-6.
1995: Adamson P C; Murphy R F; Godwin K A; Ulm E H; Balis F M
Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey.
Cancer research 1995;55(3):482-5.
1995: Blaney S M; Poplack D G; Godwin K; McCully C L; Murphy R; Balis F M
Effect of body position on ventricular CSF methotrexate concentration following intralumbar administration.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(1):177-9.
1995: Blaney S M; Cole D E; Godwin K; Sung C; Poplack D G; Balis F M
Intrathecal administration of topotecan in nonhuman primates.
Cancer chemotherapy and pharmacology 1995;36(2):121-4.
1994: Adamson P C; Poplack D G; Balis F M
The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia.
Leukemia research 1994;18(11):805-10.
1994: Mueller B U; Butler K M; Stocker V L; Balis F M; Brouwers P; Jarosinski P; Husson R N; Lewis L L; Venzon D; Pizzo P A
Clinical and pharmacokinetic evaluation of long-term therapy with didanosine in children with HIV infection.
Pediatrics 1994;94(5):724-31.
1994: Sung C; Blaney S M; Cole D E; Balis F M; Dedrick R L
A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid.
Cancer research 1994;54(19):5118-22.
1994: Izraeli S; Adamson P C; Blaney S M; Balis F M
Acute pancreatitis after ifosfamide therapy.
Cancer 1994;74(5):1627-8.
1994: Drusano G L; Balis F M; Gitterman S R; Pizzo P A
Quantitative relationships between zidovudine exposure and efficacy and toxicity.
Antimicrobial agents and chemotherapy 1994;38(8):1726-31.
1994: Bacher J D; Balis F M; McCully C L; Godwin K S
Cerebral subarachnoid sampling of cerebrospinal fluid in the rhesus monkey.
Laboratory animal science 1994;44(2):148-52.
1994: Berg S; Balis F M; McCully C L; Poplack D C
Re: Toxicity of intrathecal melphalan.
Journal of the National Cancer Institute 1994;86(6):463.
1994: Grem J L; McAtee N; Murphy R F; Hamilton J M; Balis F; Steinberg S; Arbuck S G; Setser A; Jordan E; Chen A
Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony-stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(3):560-8.
1994: Husson R N; Mueller B U; Farley M; Woods L; Kovacs A; Goldsmith J C; Ono J; Lewis L L; Balis F M; Brouwers P
Zidovudine and didanosine combination therapy in children with human immunodeficiency virus infection.
Pediatrics 1994;93(2):316-22.
1994: Berg S L; Cowan K H; Balis F M; Fisherman J S; Denicoff A M; Hillig M; Poplack D G; O'Shaughnessy J A
Pharmacokinetics of taxol and doxorubicin administered alone and in combination by continuous 72-hour infusion.
Journal of the National Cancer Institute 1994;86(2):143-5.
1993: Adamson P C; Balis F M; Hawkins M E; Murphy R F; Poplack D G
Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells.
Biochemical pharmacology 1993;46(9):1627-36.
1993: Berg S L; Balis F M; Godwin K S; Poplack D G
Pharmacokinetics, cerebrospinal fluid penetration, and metabolism of piroxantrone in the rhesus monkey.
Investigational new drugs 1993;11(4):255-61.
1993: Grem J L; McAtee N; Steinberg S M; Hamilton J M; Murphy R F; Drake J; Chisena T; Balis F; Cysyk R; Arbuck S G
A phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma.
Cancer research 1993;53(20):4828-36.
1993: Savarese D M; Denicoff A M; Berg S L; Hillig M; Baker S P; O'Shaughnessy J A; Chow C; Otterson G A; Balis F M; Poplack D G
Phase I study of high-dose piroxantrone with granulocyte colony-stimulating factor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(9):1795-803.
1993: Grem J L; McAtee N; Balis F; Murphy R; Venzon D; Kramer B; Goldspiel B; Begley M; Allegra C J
A phase II study of continuous infusion 5-fluorouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma.
Cancer 1993;72(3):663-8.
1993: Heideman R L; Packer R J; Reaman G H; Allen J C; Lange B; Horowitz M E; Steinberg S M; Gillespie A; Kovnar E H; Balis F M
A phase II evaluation of thiotepa in pediatric central nervous system malignancies.
Cancer 1993;72(1):271-5.
1993: Adamson P C; Pitot H C; Balis F M; Rubin J; Murphy R F; Poplack D G
Variability in the oral bioavailability of all-trans-retinoic acid.
Journal of the National Cancer Institute 1993;85(12):993-6.
1993: Berg S L; Savarese D M; Balis F M; Denicoff A M; Hillig M; O'Shaughnessy J A; Poplack D G; Cowan K H
Pharmacokinetics of piroxantrone in a phase I trial of piroxantrone and granulocyte-colony stimulating factor.
Cancer research 1993;53(11):2587-90.
1993: Heideman R L; McCully C; Balis F M; Poplack D G
Cerebrospinal fluid pharmacokinetics and toxicology of intraventricular and intrathecal arabinosyl-5-azacytosine (fazarabine, NSC 281272) in the nonhuman primate.
Investigational new drugs 1993;11(2-3):135-40.
1993: Rodriguez G; Brown T D; Balis F M; Craig J B; Denham C A; Kuhn J G; Havlin K; Von Hoff D D
A phase I trial of trimetrexate (NSC352122) on a daily x 5 schedule in patients with refractory adult leukemia.
Anti-cancer drugs 1993;4(2):163-6.
1993: Blaney S M; Grem J L; Balis F M; Cole D E; Adamson P C; Poplack D G
Mechanism of resistance to cyclopentenyl cytosine (CPE-C) in Molt-4 lymphoblasts.
Biochemical pharmacology 1993;45(7):1493-501.
1993: Kim S; Khatibi S; Howell S B; McCully C; Balis F M; Poplack D G
Prolongation of drug exposure in cerebrospinal fluid by encapsulation into DepoFoam.
Cancer research 1993;53(7):1596-8.
1993: Butler K M; Venzon D; Henry N; Husson R N; Mueller B U; Balis F M; Jacobsen F; Lewis L L; Pizzo P A
Pancreatitis in human immunodeficiency virus-infected children receiving dideoxyinosine.
Pediatrics 1993;91(4):747-51.
1993: Blaney S M; Balis F M; Cole D E; Craig C; Reid J M; Ames M M; Krailo M; Reaman G; Hammond D; Poplack D G
Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion.
Cancer research 1993;53(5):1032-6.
1993: Blaney S M; Cole D E; Balis F M; Godwin K; Poplack D G
Plasma and cerebrospinal fluid pharmacokinetic study of topotecan in nonhuman primates.
Cancer research 1993;53(4):725-7.
1993: Adamson P C; Boylan J F; Balis F M; Murphy R F; Godwin K A; Gudas L J; Poplack D G
Time course of induction of metabolism of all-trans-retinoic acid and the up-regulation of cellular retinoic acid-binding protein.
Cancer research 1993;53(3):472-6.
1993: Berg S L; Balis F M; McCully C L; Godwin K S; Poplack D G
Pharmacokinetics of PEG-L-asparaginase and plasma and cerebrospinal fluid L-asparagine concentrations in the rhesus monkey.
Cancer chemotherapy and pharmacology 1993;32(4):310-4.
1992: Smith M A; Adamson P C; Balis F M; Feusner J; Aronson L; Murphy R F; Horowitz M E; Reaman G; Hammond G D; Fenton R M
Phase I and pharmacokinetic evaluation of all-trans-retinoic acid in pediatric patients with cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(11):1666-73.
1992: Adamson P C; Balis F M; Smith M A; Murphy R F; Godwin K A; Poplack D G
Dose-dependent pharmacokinetics of all-trans-retinoic acid.
Journal of the National Cancer Institute 1992;84(17):1332-5.
1992: Adamson P C; Balis F M; McCully C L; Godwin K S; Poplack D G
Methotrexate pharmacokinetics following administration of recombinant carboxypeptidase-G2 in rhesus monkeys.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(8):1359-64.
1992: Blaney S M; Balis F M; Grem J; Cole D E; Adamson P C; Poplack D G
Modulation of the cytotoxic effect of cyclopentenylcytosine by its primary metabolite, cyclopentenyluridine.
Cancer research 1992;52(12):3503-5.
1992: Grem J L; Chu E; Boarman D; Balis F M; Murphy R F; McAtee N; Allegra C J
Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations.
Seminars in oncology 1992;19(2 Suppl 3):36-44.
1992: Adamson P C; Balis F M; Miser J; Arndt C; Wells R J; Gillespie A; Aronson L; Penta J S; Clendeninn N J; Poplack D G
Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule.
Cancer research 1992;52(3):521-4.
1992: Berg S L; Balis F M; Zimm S; Murphy R F; Holcenberg J; Sato J; Reaman G; Steinherz P; Gillespie A; Doherty K
Phase I/II trial and pharmacokinetics of intrathecal diaziquone in refractory meningeal malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(1):143-8.
1992: Balis F M; Pizzo P A; Butler K M; Hawkins M E; Brouwers P; Husson R N; Jacobsen F; Blaney S M; Gress J; Jarosinski P
Clinical pharmacology of 2',3'-dideoxyinosine in human immunodeficiency virus-infected children.
The Journal of infectious diseases 1992;165(1):99-104.
1992: Adamson P C; Zimm S; Ragab A H; Balis F; Steinberg S M; Kamen B A; Vietti T J; Gillespie A; Poplack D G
A phase II trial of continuous-infusion 6-mercaptopurine for childhood leukemia.
Cancer chemotherapy and pharmacology 1992;30(2):155-7.
1992: Berg S L; Balis F M; McCully C L; Parker G A; Murphy R F; Poplack D G
Intrathecal 5-fluorouracil in the rhesus monkey.
Cancer chemotherapy and pharmacology 1992;31(2):127-30.
1991: Adamson P C; Balis F M; Arndt C A; Holcenberg J S; Narang P K; Murphy R F; Gillespie A J; Poplack D G
Intrathecal 6-mercaptopurine: preclinical pharmacology, phase I/II trial, and pharmacokinetic study.
Cancer research 1991;51(22):6079-83.
1991: Balis F M; Blaney S M; Poplack D G
Antiretroviral drug development and clinical pharmacology.
The Pediatric infectious disease journal 1991;10(11):849-57.
1991: Grem J L; McAtee N; Murphy R F; Balis F M; Steinberg S M; Hamilton J M; Sorensen J M; Sartor O; Kramer B S; Goldstein L J
A pilot study of interferon alfa-2a in combination with fluorouracil plus high-dose leucovorin in metastatic gastrointestinal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(10):1811-20.
1991: Berg S L; Balis F M; McCully C L; Godwin K S; Poplack D G
Pharmacokinetics of pyrazoloacridine in the rhesus monkey.
Cancer research 1991;51(20):5467-70.
1991: Blaney S M; Balis F M; Poplack D G
Pharmacologic approaches to the treatment of meningeal malignancy.
Oncology (Williston Park, N.Y.) 1991;5(5):107-16; discussion 123, 127.
1991: Blaney S M; Balis F M; Poplack D G
Current pharmacological treatment approaches to central nervous system leukaemia.
Drugs 1991;41(5):702-16.
1991: Adamson P C; Balis F M; McCully C L; Godwin K S; Bacher J D; Walsh T J; Poplack D G
Rescue of experimental intrathecal methotrexate overdose with carboxypeptidase-G2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(4):670-4.
1991: Berg S L; Grisell D L; DeLaney T F; Balis F M
Principles of treatment of pediatric solid tumors.
Pediatric clinics of North America 1991;38(2):249-67.
1991: Butler K M; Husson R N; Balis F M
Drug trial benefited HIV children.
Nursing times 1991;87(5):10.
1991: Butler K M; Husson R N; Balis F M; Brouwers P; Eddy J; el-Amin D; Gress J; Hawkins M; Jarosinski P; Moss H
Dideoxyinosine in children with symptomatic human immunodeficiency virus infection.
The New England journal of medicine 1991;324(3):137-44.
1990: Blaney S M; Balis F M; Hegedus L; Heideman R L; McCully C; Murphy R F; Kelley J A; Poplack D G
Pharmacokinetics and metabolism of cyclopentenyl cytosine in nonhuman primates.
Cancer research 1990;50(24):7915-9.
1990: Brouwers P; Moss H; Wolters P; Eddy J; Balis F; Poplack D G; Pizzo P A
Effect of continuous-infusion zidovudine therapy on neuropsychologic functioning in children with symptomatic human immunodeficiency virus infection.
The Journal of pediatrics 1990;117(6):980-5.
1990: Adamson P C; Balis F M; Steinberg S M; Poplack D G; Holcenberg J S
Pharmacokinetics of mercaptopurine in children with acute lymphocytic leukemia.
The New England journal of medicine 1990;323(22):1565-6.
1990: Pizzo P A; Butler K; Balis F; Brouwers E; Hawkins M; Eddy J; Einloth M; Falloon J; Husson R; Jarosinski P
Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection.
The Journal of pediatrics 1990;117(5):799-808.
1990: Hawkins M E; Poplack D G; Pizzo P A; Balis F M
High-performance liquid chromatographic method for the analysis of 2',3'-dideoxycytidine in human plasma.
Journal of chromatography 1990;532(2):442-4.
1990: Adamson P C; Poplack D G; Balis F M
Pharmacology and drug resistance in childhood lymphoblastic leukemia.
Hematology/oncology clinics of North America 1990;4(5):871-94.
1990: McCully C L; Balis F M; Bacher J; Phillips J; Poplack D G
A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid.
Laboratory animal science 1990;40(5):520-5.
1990: Adamson P C; Balis F M; Miser J; Wells R J; Bleyer W A; Williams T E; Gillespie A; Penta J S; Clendeninn N J; Poplack D G
Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule.
Cancer research 1990;50(15):4464-7.
1990: Walsh T J; Lester-McCully C; Rinaldi M G; Wallace J E; Balis F M; Lee J W; Pizzo P A; Poplack D G
Penetration of SCH-39304, a new antifungal triazole, into cerebrospinal fluid of primates.
Antimicrobial agents and chemotherapy 1990;34(6):1281-4.
1990: Balis F M; Gillespie A; Belasco J; Reaman G H; Ettinger L J; Murphy R F; Doherty K; Jeffries S; Horowitz M E; Poplack D G
Phase II trial of sequential methotrexate and 5-fluorouracil with leucovorin in children with sarcomas.
Investigational new drugs 1990;8(2):181-2.
1990: Allegra C J; Jenkins J; Weiss R B; Balis F; Drake J C; Brooks J; Thomas R; Curt G A
A phase I and pharmacokinetic study of trimetrexate using a 24-hour continuous-injection schedule.
Investigational new drugs 1990;8(2):159-66.
1990: Carpen M E; Poplack D G; Pizzo P A; Balis F M
High-performance liquid chromatographic method for analysis of 2',3'-dideoxyinosine in human body fluids.
Journal of chromatography 1990;526(1):69-75.
1990: Adamson P C; Zimm S; Ragab A H; Steinberg S M; Balis F; Kamen B A; Vietti T J; Gillespie A; Poplack D G
A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors.
Cancer chemotherapy and pharmacology 1990;26(5):343-4.
1989: Rothenberg M L; Mickley L A; Cole D E; Balis F M; Tsuruo T; Poplack D G; Fojo A T
Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia.
Blood 1989;74(4):1388-95.
1989: Heideman R L; Gillespie A; Ford H; Reaman G H; Balis F M; Tan C; Sato J; Ettinger L J; Packer R J; Poplack D G
Phase I trial and pharmacokinetic evaluation of fazarabine in children.
Cancer research 1989;49(18):5213-6.
1989: Balis F M; McCully C; Gough L; Pizzo P A; Poplack D G
Pharmacokinetics of subcutaneous azidothymidine in rhesus monkeys.
Antimicrobial agents and chemotherapy 1989;33(6):810-2.
1989: Balis F M; Pizzo P A; Eddy J; Wilfert C; McKinney R; Scott G; Murphy R F; Jarosinski P F; Falloon J; Poplack D G
Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.
The Journal of pediatrics 1989;114(5):880-4.
1989: Goel R; Cleary S M; Horton C; Balis F M; Zimm S; Kirmani S; Howell S B
Selective intraperitoneal biochemical modulation of methotrexate by dipyridamole.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(2):262-9.
1989: Balis F M; Pizzo P A; Murphy R F; Eddy J; Jarosinski P F; Falloon J; Broder S; Poplack D G
The pharmacokinetics of zidovudine administered by continuous infusion in children.
Annals of internal medicine 1989;110(4):279-85.
1989: Heideman R L; Cole D E; Balis F; Sato J; Reaman G H; Packer R J; Singher L J; Ettinger L J; Gillespie A; Sam J
Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa.
Cancer research 1989;49(3):736-41.
1989: Balis F M; Jeffries S L; Lange B; Murphy R F; Doherty K M; Arndt C A; Luery N; Poplack D G
Chronopharmacokinetics of oral methotrexate and 6-mercaptopurine: is there diurnal variation in the disposition of antileukemic therapy?
The American journal of pediatric hematology/oncology 1989;11(3):324-6.
1989: Balis F M; Poplack D G
Central nervous system pharmacology of antileukemic drugs.
The American journal of pediatric hematology/oncology 1989;11(1):74-86.
1988: Balis F M; Mirro J; Reaman G H; Evans W E; McCully C; Doherty K M; Murphy R F; Jeffries S; Poplack D G
Pharmacokinetics of subcutaneous methotrexate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(12):1882-6.
1988: Pizzo P A; Eddy J; Falloon J; Balis F M; Murphy R F; Moss H; Wolters P; Brouwers P; Jarosinski P; Rubin M
Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection.
The New England journal of medicine 1988;319(14):889-96.
1988: Ramu N; Ramu A; Cole D E; Balis F M; Poplack D G; Pollard H B
Mechanism of acquired resistance to methotrexate in P388 murine leukemia cells and in their doxorubicin-resistant subline.
Israel journal of medical sciences 1988;24(9-10):477-82.
1988: Balis F M
Pharmacologic considerations in the treatment of acute lymphoblastic leukemia.
Pediatric clinics of North America 1988;35(4):835-51.
1988: Heideman R L; Balis F M; McCully C; Poplack D G
Preclinical pharmacology of arabinosyl-5-azacytidine in nonhuman primates.
Cancer research 1988;48(15):4294-8.
1988: Jarosinski P F; Moscow J A; Alexander M S; Lesko L J; Balis F M; Poplack D G
Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia.
The Journal of pediatrics 1988;112(6):996-9.
1988: Collins J M; Klecker R W; Kelley J A; Roth J S; McCully C L; Balis F M; Poplack D G
Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid.
The Journal of pharmacology and experimental therapeutics 1988;245(2):466-70.
1988: Arndt C A; Balis F M; McCully C L; Jeffries S L; Doherty K; Murphy R; Poplack D G
Bioavailability of low-dose vs high-dose 6-mercaptopurine.
Clinical pharmacology and therapeutics 1988;43(5):588-91.
1988: Heideman R L; Kelley J A; Packer R J; Reaman G H; Roth J S; Balis F; Ettinger L J; Doherty K M; Jeffries S L; Poplack D G
A pediatric phase I and pharmacokinetic study of spirohydantoin mustard.
Cancer research 1988;48(8):2292-5.
1988: Arndt C A; Balis F M; McCully C L; Colvin O M; Poplack D G
Cerebrospinal fluid penetration of active metabolites of cyclophosphamide and ifosfamide in rhesus monkeys.
Cancer research 1988;48(8):2113-5.
1988: Rogers P; Allegra C J; Murphy R F; Drake J C; Masur H; Poplack D G; Chabner B A; Parrillo J E; Lane H C; Balis F M
Bioavailability of oral trimetrexate in patients with acquired immunodeficiency syndrome.
Antimicrobial agents and chemotherapy 1988;32(3):324-6.
1988: Arndt C A; Walsh T J; McCully C L; Balis F M; Pizzo P A; Poplack D G
Fluconazole penetration into cerebrospinal fluid: implications for treating fungal infections of the central nervous system.
The Journal of infectious diseases 1988;157(1):178-80.
1987: Murphy R F; Balis F M; Poplack D G
Stability of 5-fluorouracil in whole blood and plasma.
Clinical chemistry 1987;33(12):2299-300.
1987: Arndt C A; Colvin O M; Balis F M; Lester C M; Johnson G; Poplack D G
Intrathecal administration of 4-hydroperoxycyclophosphamide in rhesus monkeys.
Cancer research 1987;47(22):5932-4.
1987: Allegra C J; Chabner B A; Tuazon C U; Ogata-Arakaki D; Baird B; Drake J C; Simmons J T; Lack E E; Shelhamer J H; Balis F
Trimetrexate for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome.
The New England journal of medicine 1987;317(16):978-85.
1987: Greene R F; Miser A W; Lester C M; Balis F M; Poplack D G
Cerebrospinal fluid and plasma pharmacokinetics of morphine infusions in pediatric cancer patients and rhesus monkeys.
Pain 1987;30(3):339-48.
1987: Balis F M; Patel R; Luks E; Doherty K M; Holcenberg J S; Tan C; Reaman G H; Belasco J; Ettinger L J; Zimm S
Pediatric phase I trial and pharmacokinetic study of trimetrexate.
Cancer research 1987;47(18):4973-6.
1987: Kelley J A; Litterst C L; Roth J S; Vistica D T; Poplack D G; Cooney D A; Nadkarni M; Balis F M; Broder S; Johns D G
The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys.
Drug metabolism and disposition: the biological fate of chemicals 1987;15(5):595-601.
1987: Balis F M; Holcenberg J S; Zimm S; Tubergen D; Collins J M; Murphy R F; Gilchrist G S; Hammond D; Poplack D G
The effect of methotrexate on the bioavailability of oral 6-mercaptopurine.
Clinical pharmacology and therapeutics 1987;41(4):384-7.
1987: Balis F M; Lester C M; Chrousos G P; Heideman R L; Poplack D G
Differences in cerebrospinal fluid penetration of corticosteroids: possible relationship to the prevention of meningeal leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(2):202-7.
1987: Winick N J; Kamen B A; Balis F M; Holcenberg J; Lester C M; Poplack D G
Folate and methotrexate polyglutamate tissue levels in rhesus monkeys following chronic low-dose methotrexate.
Cancer drug delivery 1987;4(1):25-31.
1986: Poplack D G; Balis F M; Zimm S
The pharmacology of orally administered chemotherapy. A reappraisal.
Cancer 1986;58(2 Suppl):473-80.
1986: Balis F M
Pharmacokinetic drug interactions of commonly used anticancer drugs.
Clinical pharmacokinetics 1986;11(3):223-35.
1986: Balis F M; Lester C M; Poplack D G
Pharmacokinetics of trimetrexate (NSC 352122) in monkeys.
Cancer research 1986;46(1):169-74.
1986: Balis F M; Murphy R F; Lester C M; Poplack D G
The influence of route of administration on the hepatic uptake of methotrexate.
Cancer drug delivery 1986;3(4):239-42.
1986: Heideman R L; Balis F M; Zimm S; Lester C M; Poplack D G
The effect of amitriptyline on the central nervous system penetration of methotrexate.
Cancer drug delivery 1986;3(4):219-22.
1986: Riccardi R; Balis F M; Ferrara P; Lasorella A; Poplack D G; Mastrangelo R
Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.
Pediatric hematology and oncology 1986;3(4):319-24.
1985: Balis F M; Lange B J; Packer R J; Holcenberg J S; Ettinger L J; Sallan S E; Heideman R L; Zimm S; Smithson W A; Cogliano-Shutta N A
Pediatric phase I trial and pharmacokinetic study of tiazofurin (NSC 286193).
Cancer research 1985;45(10):5169-72.
1985: Grygiel J J; Balis F M; Collins J M; Lester C M; Poplack D G
Pharmacokinetics of tiazofurin in the plasma and cerebrospinal fluid of rhesus monkeys.
Cancer research 1985;45(5):2037-9.
1985: Zimm S; Ettinger L J; Holcenberg J S; Kamen B A; Vietti T J; Belasco J; Cogliano-Shutta N; Balis F; Lavi L E; Collins J M
Phase I and clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion.
Cancer research 1985;45(4):1869-73.
1985: Balis F M; Savitch J L; Bleyer W A; Reaman G H; Poplack D G
Remission induction of meningeal leukemia with high-dose intravenous methotrexate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(4):485-9.
1985: Morse M; Savitch J; Balis F; Miser J; Feusner J; Reaman G; Poplack D; Bleyer A
Altered central nervous system pharmacology of methotrexate in childhood leukemia: another sign of meningeal relapse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(1):19-24.
1983: Balis F M; Savitch J L; Bleyer W A
Pharmacokinetics of oral methotrexate in children.
Cancer research 1983;43(5):2342-5.
1983: Balis F M; Holcenberg J S; Bleyer W A
Clinical pharmacokinetics of commonly used anticancer drugs.
Clinical pharmacokinetics 1983;8(3):202-32.
1982: Johnson F L; Balis F M
Hepatopathy following irradiation and chemotherapy for Wilms' tumor.
The American journal of pediatric hematology/oncology 1982;4(2):217-21.

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