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FRANK BALIS

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AeRang Kim; Bruce Korf; Staci Martin; Naira Muradyan; Alyssa Reddy; Kathleen Tepas; Baris Turkbey; FRANK BALIS; Peter L Choyke; Eva Dombi; Elizabeth Fox; Nalini Jayaprakash; Pamela Wolters; BRIGITTE WIDEMANN
Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas.
BRIGITTE WIDEMANN; Peter Charles Adamson; FRANK BALIS; Sylvain Baruchel; Michael Burke; Elizabeth Fox; Julia Glade Bender; Ashish Ingle; Aerang Kim; Diana Stempak; Brenda J Weigel; Susan M Blaney
A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report.
Meredith K Chuk; Alberta Aikin; FRANK BALIS; Eliel Bayever; Trish Whitcomb; BRIGITTE WIDEMANN; Peter Zannikos; Elizabeth Fox
A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis®, ET-743) in children and adolescents with relapsed or refractory solid tumors.

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All Publications

2013: AeRang Kim; Bruce Korf; Staci Martin; Naira Muradyan; Alyssa Reddy; Kathleen Tepas; Baris Turkbey; FRANK BALIS; Peter L Choyke; Eva Dombi; Elizabeth Fox; Nalini Jayaprakash; Pamela Wolters; BRIGITTE WIDEMANN
Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas.
Pediatric blood & cancer 2013;60(3):396-401.
2012: BRIGITTE WIDEMANN; Peter Charles Adamson; FRANK BALIS; Sylvain Baruchel; Michael Burke; Elizabeth Fox; Julia Glade Bender; Ashish Ingle; Aerang Kim; Diana Stempak; Brenda J Weigel; Susan M Blaney
A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(21):6011-22.
2012: Meredith K Chuk; Alberta Aikin; FRANK BALIS; Eliel Bayever; Trish Whitcomb; BRIGITTE WIDEMANN; Peter Zannikos; Elizabeth Fox
A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis®, ET-743) in children and adolescents with relapsed or refractory solid tumors.
Pediatric blood & cancer 2012;59(5):865-9.
2012: AeRang Kim; Cynthia McCully; FRANK BALIS; Diane E Cole; Rafael Cruz; Elizabeth Fox; BRIGITTE WIDEMANN
The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates.
Investigational new drugs 2012;30(2):524-8.
2012: Robert F Murphy; Robert Robey; FRANK BALIS; Nicholas P Farrell; Edina Komlodi-Pasztor; Tito Fojo
Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin.
Cell cycle (Georgetown, Tex.) 2012;11(5):963-73.
2012: Maya Lodish; Leigh Marcus; Ninet Sinaii; Alberta Aikin; FRANK BALIS; Clara C Chen; Meredith Chuk; Urania Dagalakis; Eva Dombi; Elizabeth Fox; Samuel Wells; Patricia Whitcomb; BRIGITTE WIDEMANN; Constantine A Stratakis
(111)In-octreotide scintigraphy for identification of metastatic medullary thyroid carcinoma in children and adolescents.
The Journal of clinical endocrinology and metabolism 2012;97(2):E207-12.
2012: Katherine E Warren; FRANK BALIS; Stacey L Berg; James M Boyett; J Russell Geyer; Stewart Goldman; Sri Gururangan; Roger E McLendon; Jane E. Minturn; Roger J Packer; Ian F Pollack; Tina Young Poussaint; Dana Wallace; Larry E Kun
A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.
Journal of neuro-oncology 2012;106(3):643-9.
2012: Leigh Marcus; Cynthia McCully; Elizabeth Fox; FRANK BALIS; Katherine E Warren; Raphael Cruz; Edward McNiff; Robert Murphy; Thorsten Meyer; BRIGITTE WIDEMANN
The plasma and cerebrospinal fluid pharmacokinetics of the platinum analog satraplatin after intravenous administration in non-human primates.
Cancer chemotherapy and pharmacology 2012;69(1):247-52.
2011: AeRang Kim; Jeffrey Solomon; FRANK BALIS; Eva Dombi; Elizabeth Fox; BRIGITTE WIDEMANN
Automated volumetric growth plate measurement using magnetic resonance imaging for monitoring skeletal toxicity in children treated on investigational drug trials.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(18):5982-90.
2011: Meredith K Chuk; Diane E Cole; Cynthia McCully; Natalia A Loktionova; Anthony E Pegg; Robert J Parker; Gary T Pauly; BRIGITTE WIDEMANN; FRANK BALIS; Elizabeth Fox
Plasma and CNS pharmacokinetics of O4-benzylfolic acid (O4BF) and metabolite in a non-human primate model.
Cancer chemotherapy and pharmacology 2011;67(6):1291-7.
2011: Richard Aplenc; Susan M Blaney; Lewis C Strauss; FRANK BALIS; Suzanne Shusterman; Ashish Mark Ingle; Shruti Agrawal; Junfeng Sun; John J Wright; Peter Charles Adamson
Pediatric phase I trial and pharmacokinetic study of dasatinib: a report from the children's oncology group phase I consortium.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(7):839-44.
2011: R Bagatell; C E Herzog; T M Trippett; J F Grippo; G Cirrincione-Dall; Elizabeth Fox; M Macy; J Bish; P Whitcomb; A Aikin; G Wright; S Yurasov; FRANK BALIS; L Gore
Pharmacokinetically guided phase 1 trial of the IGF-1 receptor antagonist RG1507 in children with recurrent or refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(3):611-9.
2011: Ronan J Kelly; Deborah Draper; Clara C Chen; Robert W Robey; William D Figg; Richard L Piekarz; Xiaohong Chen; Erin R Gardner; FRANK BALIS; Aradhana Venkatesan; Seth M Steinberg; Tito Fojo; Susan E Bates
A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(3):569-80.
2011: BRIGITTE WIDEMANN; Robert J Arceci; Nalini Jayaprakash; Elizabeth Fox; Peter Zannikos; Wendy Goodspeed; Anne Goodwin; John J Wright; Susan M Blaney; Peter Charles Adamson; FRANK BALIS
Phase 1 trial and pharmacokinetic study of the farnesyl transferase inhibitor tipifarnib in children and adolescents with refractory leukemias: a report from the Children's Oncology Group.
Pediatric blood & cancer 2011;56(2):226-33.
2010: Elizabeth Fox; Richard Aplenc; Rochelle Bagatell; Meredith K Chuk; Eva Dombi; Wendy Goodspeed; Anne Goodwin; Marie Kromplewski; Nalini Jayaprakash; Marcelo Marotti; Kathryn H Brown; Barbara Wenrich; Peter Charles Adamson; BRIGITTE WIDEMANN; FRANK BALIS
A phase 1 trial and pharmacokinetic study of cediranib, an orally bioavailable pan-vascular endothelial growth factor receptor inhibitor, in children and adolescents with refractory solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(35):5174-81.
2010: Elizabeth Fox; FRANK BALIS
Commentary.
Clinical chemistry 2010;56(12):1795.
2010: BRIGITTE WIDEMANN; FRANK BALIS; AeRang Kim; Matthew Boron; Nalini Jayaprakash; Aiman Shalabi; Michelle O'Brien; Michelle Eby; Diane E Cole; RF Murphy; Elizabeth Fox; Percy Ivy; Peter Charles Adamson
Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(25):3979-86.
2010: Elizabeth Fox; John M Maris; Susan Cohn; Wendy Goodspeed; Anne Goodwin; Marie Kromplewski; Diane Medina; Hao Xiong; Andrew Krivoshik; BRIGITTE WIDEMANN; Peter Charles Adamson; FRANK BALIS
Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors.
Cancer chemotherapy and pharmacology 2010;66(4):737-43.
2010: Holly Meany; FRANK BALIS; Alberta Aikin; Patricia Whitcomb; Robert F Murphy; Seth M Steinberg; BRIGITTE WIDEMANN; Elizabeth Fox
Pediatric phase I trial design using maximum target inhibition as the primary endpoint.
Journal of the National Cancer Institute 2010;102(12):909-12.
2010: Shana Jacobs; Cynthia McCully; RF Murphy; John Bacher; FRANK BALIS; Elizabeth Fox
Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates.
Cancer chemotherapy and pharmacology 2010;65(5):817-24.
2010: Shana Jacobs; Elizabeth Fox; Mark Krailo; Gwen Hartley; Fariba Navid; Leonard H Wexler; Susan M Blaney; Anne Goodwin; Wendy Goodspeed; FRANK BALIS; Peter Charles Adamson; BRIGITTE WIDEMANN
Phase II trial of ixabepilone administered daily for five days in children and young adults with refractory solid tumors: a report from the children's oncology group.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(2):750-4.
2010: Dana M Sepe; Jill P Ginsberg; FRANK BALIS
Dexrazoxane as a cardioprotectant in children receiving anthracyclines.
The oncologist 2010;15(11):1220-6.
2010: Holly J Meany; Dan L Sackett; John M Maris; Yvona Ward; Andrew Krivoshik; Susan Cohn; Seth M Steinberg; FRANK BALIS; Elizabeth Fox
Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro.
Pediatric blood & cancer 2010;54(1):47-54.
2009: Elizabeth Fox; BRIGITTE WIDEMANN; Douglas S Hawkins; Nalini Jayaprakash; Ramzi Dagher; Alberta A Aikin; Donna Bernstein; Lauren Long; CRYSTAL MACKALL; Lee Helman; Seth M Steinberg; FRANK BALIS
Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(23):7361-7.
2009: Holly J Meany; Katherine E Warren; Elizabeth Fox; Diane E Cole; Alberta Aikin; FRANK BALIS
Pharmacokinetics of temozolomide administered in combination with O6-benzylguanine in children and adolescents with refractory solid tumors.
Cancer chemotherapy and pharmacology 2009;65(1):137-42.
2009: A Kim; Andrea Gillespie; Eva Dombi; Amy K Goodwin; W Goodspeed; Elizabeth Fox; FRANK BALIS; BRIGITTE WIDEMANN
Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas.
Neurology 2009;73(16):1273-9.
2009: Kristi Wojtuszewski Poulin; Aleksandr V Smirnov; Mary E Hawkins; FRANK BALIS; Jay R Knutson
Conformational heterogeneity and quasi-static self-quenching in DNA containing a fluorescent guanine analogue, 3MI or 6MI.
Biochemistry 2009;48(37):8861-8.
2009: Elizabeth Fox; Deborah Citrin; FRANK BALIS
The legacy of cancer therapy in children.
Journal of the National Cancer Institute 2009;101(16):1105-7.
2009: Meredith K Chuk; FRANK BALIS; Elizabeth Fox
Trabectedin.
The oncologist 2009;14(8):794-9.
2009: AeRang Kim; FRANK BALIS; BRIGITTE WIDEMANN
Sorafenib and sunitinib.
The oncologist 2009;14(8):800-5.
2009: Jame Abraham; Maureen Edgerly; Richard Wilson; Clara Chen; Ann Rutt; Susan Bakke; Rob Robey; Andrew Dwyer; Barry Goldspiel; FRANK BALIS; Olaf van Tellingen; Susan E Bates; Tito Fojo
A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3574-82.
2009: FRANK BALIS; E Fox; BRIGITTE WIDEMANN; Peter Charles Adamson
Clinical drug development for childhood cancers.
Clinical pharmacology and therapeutics 2009;85(2):127-9.
2009: BRIGITTE WIDEMANN; Wendy Goodspeed; Anne Goodwin; Tito Fojo; FRANK BALIS; Elizabeth Fox
Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(4):550-6.
2008: Katherine E Warren; Cynthia McCully; Henrik Dvinge; Jette Tjørnelund; Maxwell Sehested; Henri S Lichenstein; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.
Cancer chemotherapy and pharmacology 2008;62(3):433-7.
2008: Holly J Meany; Elizabeth Fox; Cynthia McCully; Chris Tucker; FRANK BALIS
The plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite (OSI-420) after intravenous administration of erlotinib in non-human primates.
Cancer chemotherapy and pharmacology 2008;62(3):387-92.
2008: Ronald J Bernardi; Lisa R Bomgaars; Elizabeth Fox; FRANK BALIS; Merrill J Egorin; Theodore F Lagattuta; Alberta Aikin; Patricia Whitcomb; Jamie L Renbarger; Frank S Lieberman; Stacey L Berg; Susan M Blaney
Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis.
Cancer chemotherapy and pharmacology 2008;62(2):355-61.
2008: Aerang Kim; Elizabeth Fox; Katherine Warren; Susan M Blaney; Stacey L Berg; Peter Charles Adamson; Madeleine Libucha; Elena Byrley; FRANK BALIS; BRIGITTE WIDEMANN
Characteristics and outcome of pediatric patients enrolled in phase I oncology trials.
The oncologist 2008;13(6):679-89.
2008: Elizabeth Fox; John M Maris; BRIGITTE WIDEMANN; Wendy Goodspeed; Anne Goodwin; Marie Kromplewski; Molly E Fouts; Diane Medina; Susan Cohn; Andrew Krivoshik; Anne Hagey; Peter Charles Adamson; FRANK BALIS
A phase I study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 21 days every 28 days in pediatric patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1111-5.
2008: Elizabeth Fox; Bassem I Razzouk; BRIGITTE WIDEMANN; Shaun Xiao; Michelle O'Brien; Wendy Goodspeed; Gregory H Reaman; Susan M Blaney; Anthony J Murgo; FRANK BALIS; Peter Charles Adamson
Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma.
Blood 2008;111(2):566-73.
2007: Peter Charles Adamson; Katherine K Matthay; Michelle O'Brien; Gregory H Reaman; Judith K Sato; FRANK BALIS
A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch, NCI and Children's Oncology Group Study.
Pediatric blood & cancer 2007;49(5):661-5.
2007: Steve Y Cho; Elizabeth Fox; Cynthia McCully; Joy Bauch; Kennan Marsh; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of intravenously administered ABT-751 in non-human primates.
Cancer chemotherapy and pharmacology 2007;60(4):563-7.
2007: Shana S Jacobs; Linda C Stork; Bruce C Bostrom; Raymond J Hutchinson; John Holcenberg; Gregory H Reaman; Gary R Erdmann; Janet Franklin; Joseph P Neglia; Seth M Steinberg; FRANK BALIS; Peter Charles Adamson
Substitution of oral and intravenous thioguanine for mercaptopurine in a treatment regimen for children with standard risk acute lymphoblastic leukemia: a collaborative Children's Oncology Group/National Cancer Institute pilot trial (CCG-1942).
Pediatric blood & cancer 2007;49(3):250-5.
2007: Eva Dombi; Jeffrey Solomon; Andrea Gillespie; Elizabeth Fox; FRANK BALIS; Nicholas Patronas; Bruce Korf; Dusica Babovic-Vuksanovic; Roger J Packer; J Belasco; S Goldman; Regina I Jakacki; M Kieran; S M Steinberg; BRIGITTE WIDEMANN
NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.
Neurology 2007;68(9):643-7.
2006: Paul C Nathan; Trish Whitcomb; Pamela L Wolters; Seth M Steinberg; FRANK BALIS; Pim Brouwers; Sally Hunsberger; James Feusner; Harland Sather; James S Miser; Lorrie F Odom; David G Poplack; Gregory Reaman; Archie Bleyer
Very high-dose methotrexate (33.6 g/m(2)) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children's Cancer Group trials CCG-191P, CCG-134P and CCG-144P.
Leukemia & lymphoma 2006;47(12):2488-504.
2006: Katherine Warren; Regina I Jakacki; BRIGITTE WIDEMANN; Alberta Aikin; Madeleine Libucha; Roger Packer; Gilbert Vezina; Gregory Reaman; D Shaw; Mark Krailo; C Osborne; J Cehelsky; D Caldwell; J Stanwood; Seth M Steinberg; FRANK BALIS
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group.
Cancer chemotherapy and pharmacology 2006;58(3):343-7.
2006: Elizabeth Fox; John M Maris; BRIGITTE WIDEMANN; Kysa Meek; Anne Goodwin; Wendy Goodspeed; Marie Kromplewski; Molly E Fouts; Diane Medina; Steve Y Cho; Susan Cohn; Andrew Krivoshik; Anne Hagey; Peter Charles Adamson; FRANK BALIS
A phase 1 study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 7 days every 21 days in pediatric patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4882-7.
2006: BRIGITTE WIDEMANN; Wanda L Salzer; Robert J Arceci; Susan M Blaney; Elizabeth Fox; David W End; Andrea Gillespie; Patricia Whitcomb; Joseph S Palumbo; Aaron Pitney; Nalini Jayaprakash; Peter Zannikos; FRANK BALIS
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(3):507-16.
2005: Rohan Hazra; Rachel I Gafni; Frank Maldarelli; FRANK BALIS; Antonella N Tullio; Ellen DeCarlo; Carol J Worrell; Seth M Steinberg; John F Flaherty; Kitty Yale; Brian P Kearney; Steven L Zeichner
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infection.
Pediatrics 2005;116(6):e846-54.
2005: Katherine E Warren; Alberta Aikin; Madeleine Libucha; BRIGITTE WIDEMANN; Elizabeth Fox; Roger J Packer; FRANK BALIS
Phase I study of O6-benzylguanine and temozolomide administered daily for 5 days to pediatric patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7646-53.
2005: V Koneti Rao; Turid Knutsen; Thomas Ried; Danny Wangsa; Bernard Mike Flynn; Gregory Langham; Merrill J Egorin; Diane Cole; FRANK BALIS; Seth M Steinberg; Susan Bates; Tito Fojo
The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration.
Mutation research 2005;583(2):105-19.
2005: Sen H Zhuang; Manish Agrawal; Maureen Edgerly; Susan Bakke; Herb Kotz; Paul Thambi; Ann Rutt; FRANK BALIS; Susan Bates; Tito Fojo
A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days.
Cancer 2005;103(9):1932-8.
2005: Susan M Blaney; FRANK BALIS; Stacey Berg; Carola A S Arndt; Richard L Heideman; J Russell Geyer; Roger Packer; Peter Charles Adamson; Kurt A Jaeckle; Renee Klenke; Alberta Aikin; Robert Murphy; Cynthia McCully; David G Poplack
Intrathecal mafosfamide: a preclinical pharmacology and phase I trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(7):1555-63.
2005: Shana S Jacobs; Elizabeth Fox; Christopher Dennie; Lindsey B Morgan; Cynthia McCully; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of intravenous oxaliplatin, cisplatin, and carboplatin in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1669-74.
2005: Peter F Lebowitz; Jennifer Eng-Wong; BRIGITTE WIDEMANN; FRANK BALIS; Nalini Jayaprakash; Catherine Chow; Geoff Clark; Susan B Gantz; David Venzon; Jo Anne Zujewski
A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1247-52.
2004: BRIGITTE WIDEMANN; FRANK BALIS; Aiman Shalabi; Matthew Boron; Michelle O'Brien; Diane E Cole; Nalini Jayaprakash; Percy Ivy; Valerie P Castle; Karin M Muraszko; Christopher L Moertel; Robert Trueworthy; Robert C Hermann; Ali Moussa; Stuart Hinton; Gregory Reaman; David G Poplack; Peter Charles Adamson
Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.
Journal of the National Cancer Institute 2004;96(20):1557-9.
2004: Katherine Warren; Anne Gervais; Alberta Aikin; Merrill J Egorin; FRANK BALIS
Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors.
Cancer chemotherapy and pharmacology 2004;54(3):206-12.
2004: Lawrence A Wolfraim; Tania Fernandez; Mizuko Mamura; Walter L Fuller; Rajesh Kumar; Diane E Cole; Stacey DaCosta Byfield; Angelina Felici; Kathleen C Flanders; Thomas M Walz; Anita B Roberts; Peter D Aplan; FRANK BALIS; John J Letterio
Loss of Smad3 in acute T-cell lymphoblastic leukemia.
The New England journal of medicine 2004;351(6):552-9.
2004: Susan E Bates; Susan Bakke; Min Kang; Robert W Robey; Suoping Zhai; Paul Thambi; Clara C Chen; Sheela Patil; Tom Smith; Seth M Steinberg; Maria Merino; Barry Goldspiel; Beverly Meadows; Wilfred D Stein; Peter Choyke; FRANK BALIS; William D Figg; Tito Fojo
A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4724-33.
2004: Peter Charles Adamson; Susan M Blaney; BRIGITTE WIDEMANN; Brenda Joyce Kitchen; RF Murphy; Alison L Hannah; Gillian F Cropp; M Patel; A F Gillespie; P G Whitcomb; FRANK BALIS
Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101.
Cancer chemotherapy and pharmacology 2004;53(6):482-8.
2004: BRIGITTE WIDEMANN; FRANK BALIS; Beate Kempf-Bielack; Stefan S Bielack; Charles B Pratt; Stefano Ferrari; Gaetano Bacci; Alan W Craft; Peter Charles Adamson
High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma.
Cancer 2004;100(10):2222-32.
2004: Kathleen Neville; Robert A Parise; Patrick Thompson; Alexander Aleksic; Merrill J Egorin; FRANK BALIS; Leticia McGuffey; Cynthia McCully; Stacey L Berg; Susan M Blaney
Plasma and cerebrospinal fluid pharmacokinetics of imatinib after administration to nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2525-9.
2004: Mary E Hawkins; FRANK BALIS
Use of pteridine nucleoside analogs as hybridization probes.
Nucleic acids research 2004;32(7):e62.
2004: Rohan Hazra; FRANK BALIS; Antonella N Tullio; Ellen DeCarlo; Carol J Worrell; Seth M Steinberg; John F Flaherty; Kitty Yale; Marianne Poblenz; Brian P Kearney; Lijie Zhong; Dion F Coakley; Stephane Blanche; Jean Louis Bresson; Judith A Zuckerman; Steven L Zeichner
Single-dose and steady-state pharmacokinetics of tenofovir disoproxil fumarate in human immunodeficiency virus-infected children.
Antimicrobial agents and chemotherapy 2004;48(1):124-9.
2003: Patrick Thompson; FRANK BALIS; Baruti M Serabe; Stacey Berg; Peter Charles Adamson; Renee Klenke; Alberta Aiken; Roger Packer; Daryl J Murry; Regina I Jakacki; Susan M Blaney
Pharmacokinetics of phenylacetate administered as a 30-min infusion in children with refractory cancer.
Cancer chemotherapy and pharmacology 2003;52(5):417-23.
2003: Wanda L Salzer; Seth M Steinberg; David J Liewehr; Alison G Freifeld; FRANK BALIS; BRIGITTE WIDEMANN
Evaluation and treatment of fever in the non-neutropenic child with cancer.
Journal of pediatric hematology/oncology 2003;25(8):606-12.
2003: Jame Abraham; Manish Agrawal; Susan Bakke; Ann Rutt; Maureen Edgerly; FRANK BALIS; BRIGITTE WIDEMANN; Louis Davis; Bharat D Damle; Daryl Sonnichsen; David Lebwohl; Susan Bates; Herb Kotz; Tito Fojo
Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(9):1866-73.
2003: Mahendra Patel; Cynthia McCully; Karen Godwin; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of intravenous temozolomide in non-human primates.
Journal of neuro-oncology 2003;61(3):203-7.
2003: Manish Agrawal; Jame Abraham; FRANK BALIS; Maureen Edgerly; Wilfred D Stein; Susan Bates; Tito Fojo; Clara C Chen
Increased 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):650-6.
2003: Susan M Blaney; Richard L Heideman; Stacey Berg; Peter Charles Adamson; Andrea Gillespie; J Russell Geyer; Roger Packer; Kate Matthay; Kurt A Jaeckle; Diane Cole; Nancy Kuttesch; David G Poplack; FRANK BALIS
Phase I clinical trial of intrathecal topotecan in patients with neoplastic meningitis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(1):143-7.
2002: Merrill J Egorin; Eleanor G Zuhowski; Cynthia M McCully; Susan M Blaney; Jody Z Kerr; Stacey L Berg; FRANK BALIS
Pharmacokinetics of intrathecal gemcitabine in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2437-42.
2002: Robert J Lutz; Katherine Warren; FRANK BALIS; Nicholas Patronas; Robert L Dedrick
Mixing during intravertebral arterial infusions in an in vitro model.
Journal of neuro-oncology 2002;58(2):95-106.
2002: Elizabeth Fox; Peter M Bungay; John Bacher; Cynthia McCully; Robert L Dedrick; FRANK BALIS
Zidovudine concentration in brain extracellular fluid measured by microdialysis: steady-state and transient results in rhesus monkey.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1003-11.
2002: Wyndham H Wilson; Michael L Grossbard; Stefania Pittaluga; Diane Cole; Deborah Pearson; Nicole Drbohlav; Seth M Steinberg; Richard F Little; John Janik; Martin Gutierrez; Mark Raffeld; Louis Staudt; Bruce D Cheson; Dan Longo; Nancy Harris; Elaine S Jaffe; Bruce A Chabner; Robert Wittes; FRANK BALIS
Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy.
Blood 2002;99(8):2685-93.
2002: FRANK BALIS
Evolution of anticancer drug discovery and the role of cell-based screening.
Journal of the National Cancer Institute 2002;94(2):78-9.
2002: Elizabeth Fox; Gregory A Curt; FRANK BALIS
Clinical trial design for target-based therapy.
The oncologist 2002;7(5):401-9.
2001: Mary E Hawkins; W Pfleiderer; O Jungmann; FRANK BALIS
Synthesis and fluorescence characterization of pteridine adenosine nucleoside analogs for DNA incorporation.
Analytical biochemistry 2001;298(2):231-40.
2001: Katherine E Warren; M C Patel; Alberta Aikin; BRIGITTE WIDEMANN; Madeleine Libucha; Peter Charles Adamson; R Neuwirth; D Benziger; T O'Toole; K Ford; Nicholas Patronas; Roger J Packer; FRANK BALIS
Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors.
Cancer chemotherapy and pharmacology 2001;48(4):275-82.
2001: Peter Charles Adamson; BRIGITTE WIDEMANN; Gregory H Reaman; Nita L Seibel; RF Murphy; A F Gillespie; FRANK BALIS
A phase I trial and pharmacokinetic study of 9-cis-retinoic acid (ALRT1057) in pediatric patients with refractory cancer: a joint Pediatric Oncology Branch, National Cancer Institute, and Children's Cancer Group study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3034-9.
2001: Katherine E Warren; N Patronas; Alberta Aikin; P S Albert; FRANK BALIS
Comparison of one-, two-, and three-dimensional measurements of childhood brain tumors.
Journal of the National Cancer Institute 2001;93(18):1401-5.
2001: Wanda L Salzer; BRIGITTE WIDEMANN; Cynthia McCully; Peter Charles Adamson; FRANK BALIS
Effect of probenecid on ventricular cerebrospinal fluid methotrexate pharmacokinetics after intralumbar administration in nonhuman primates.
Cancer chemotherapy and pharmacology 2001;48(3):235-40.
2001: Peter M Bungay; Robert L Dedrick; Elizabeth Fox; FRANK BALIS
Probe calibration in transient microdialysis in vivo.
Pharmaceutical research 2001;18(3):361-6.
2001: E S Lowe; Brenda Joyce Kitchen; Gary R Erdmann; Linda C Stork; Bruce C Bostrom; Raymond J Hutchinson; John Holcenberg; Gregory H Reaman; W Woods; Janet Franklin; BRIGITTE WIDEMANN; FRANK BALIS; RF Murphy; Peter Charles Adamson
Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study.
Cancer chemotherapy and pharmacology 2001;47(3):199-205.
2001: Jean L Grem; Mary Quinn; Abdel-Salam Attia Ismail; Chris H Takimoto; Richard M Lush; David J Liewehr; Seth M Steinberg; FRANK BALIS; Alice P Chen; Brian P Monahan; Nancy Harold; W Corse; Janet Pang; RF Murphy; Carmen J Allegra; J Michael Hamilton
Pharmacokinetics and pharmacodynamic effects of 5-fluorouracil given as a one-hour intravenous infusion.
Cancer chemotherapy and pharmacology 2001;47(2):117-25.
2000: Timothy J Kinsella; Jane E Schupp; TW Davis; Suzanne E Berry; Hwa-shin Hwang; K Warren; FRANK BALIS; J Barnett; Howard Sands
Preclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3670-9.
2000: L Long; Stacey L Berg; S K Roy; Cynthia McCully; H W Song-Yoo; Robert C Moschel; FRANK BALIS; M Eileen Dolan
Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3662-9.
2000: BRIGITTE WIDEMANN; E Sung; L Anderson; Wanda L Salzer; FRANK BALIS; K S Monitjo; Cynthia McCully; M Hawkins; Peter Charles Adamson
Pharmacokinetics and metabolism of the methotrexate metabolite 2, 4-diamino-N(10)-methylpteroic acid.
The Journal of pharmacology and experimental therapeutics 2000;294(3):894-901.
2000: A M Moser; M Patel; H Yoo; FRANK BALIS; Mary E Hawkins
Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.
Analytical biochemistry 2000;281(2):216-22.
2000: Katherine E Warren; Cynthia M McCully; THOMAS WALSH; FRANK BALIS
Effect of fluconazole on the pharmacokinetics of doxorubicin in nonhuman primates.
Antimicrobial agents and chemotherapy 2000;44(4):1100-1.
2000: Katherine E Warren; Joseph A Frank; J L Black; R S Hill; Jeff H Duyn; Alberta Aikin; Bobbi K Lewis; Peter Charles Adamson; FRANK BALIS
Proton magnetic resonance spectroscopic imaging in children with recurrent primary brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(5):1020-6.
2000: Wyndham H Wilson; Lynn Sorbara; William D Figg; E K Mont; Edward A Sausville; Katherine E Warren; FRANK BALIS; Kenneth S. Bauer; Mark Raffeld; Adrian M Senderowicz; Anne Monks
Modulation of clinical drug resistance in a B cell lymphoma patient by the protein kinase inhibitor 7-hydroxystaurosporine: presentation of a novel therapeutic paradigm.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):415-21.
2000: FRANK BALIS
Clinical trials in childhood cancers.
The oncologist 2000;5(3):xii-xiii.
2000: FRANK BALIS; Susan M Blaney; Cynthia McCully; John Bacher; RF Murphy; David G Poplack
Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration.
Cancer chemotherapy and pharmacology 2000;45(3):259-64.
2000: Katherine E Warren; M C Patel; Cynthia M McCully; L M Montuenga; FRANK BALIS
Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates.
Cancer chemotherapy and pharmacology 2000;45(3):207-12.
1999: FRANK BALIS; Peter Charles Adamson
Application of pharmacogenetics to optimization of mercaptopurine dosing.
Journal of the National Cancer Institute 1999;91(23):1983-5.
1999: Brenda Joyce Kitchen; Ann B Moser; E Lowe; FRANK BALIS; BRIGITTE WIDEMANN; L Anderson; J Strong; Susan M Blaney; Stacey L Berg; Michelle O'Brien; Peter Charles Adamson
Thioguanine administered as a continuous intravenous infusion to pediatric patients is metabolized to the novel metabolite 8-hydroxy-thioguanine.
The Journal of pharmacology and experimental therapeutics 1999;291(2):870-4.
1999: JS Roth; Cynthia M McCully; FRANK BALIS; David G Poplack; James A Kelley
2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(10):1128-32.
1999: Nita L Seibel; Susan M Blaney; Michelle O'Brien; Mark Krailo; Raymond J Hutchinson; Revonda B Mosher; FRANK BALIS; Gregory H Reaman
Phase I trial of docetaxel with filgrastim support in pediatric patients with refractory solid tumors: a collaborative Pediatric Oncology Branch, National Cancer Institute and Children's Cancer Group trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):733-7.
1999: DP Callender; Nalini Jayaprakash; A Bell; Vidmantas Petraitis; Ruta Petraitiene; M Candelario; Robert L Schaufele; J M Dunn; Shizuko Sei; THOMAS WALSH; FRANK BALIS; R Petratienes
Pharmacokinetics of oral zidovudine entrapped in biodegradable nanospheres in rabbits.
Antimicrobial agents and chemotherapy 1999;43(4):972-4.
1999: BRIGITTE WIDEMANN; FRANK BALIS; Peter Charles Adamson
Dihydrofolate reductase enzyme inhibition assay for plasma methotrexate determination using a 96-well microplate reader.
Clinical chemistry 1999;45(2):223-8.
1999: A M Moser; Peter Charles Adamson; Andrea Gillespie; David G Poplack; FRANK BALIS
Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma.
Cancer 1999;85(2):511-6.
1999: BRIGITTE WIDEMANN; FRANK BALIS; Karen Godwin; Cynthia McCully; Peter Charles Adamson
The plasma pharmacokinetics and cerebrospinal fluid penetration of the thymidylate synthase inhibitor raltitrexed (Tomudex) in a nonhuman primate model.
Cancer chemotherapy and pharmacology 1999;44(6):439-43.
1999: Stacey L Berg; J Reid; Karen Godwin; Daryl J Murry; David G Poplack; FRANK BALIS; Matthew M Ames
Pharmacokinetics and cerebrospinal fluid penetration of daunorubicin, idarubicin, and their metabolites in the nonhuman primate model.
Journal of pediatric hematology/oncology 1999;21(1):26-30.
1998: BU Mueller; L L Lewis; G J Yuen; M Farley; A Keller; J A Church; J C Goldsmith; DJ Venzon; M Rubin; PA Pizzo; FRANK BALIS
Serum and cerebrospinal fluid pharmacokinetics of intravenous and oral lamivudine in human immunodeficiency virus-infected children.
Antimicrobial agents and chemotherapy 1998;42(12):3187-92.
1998: FRANK BALIS; John Holcenberg; David G Poplack; J Ge; Harland Sather; RF Murphy; M M Ames; M J Waskerwitz; DG Tubergen; S Zimm; G S Gilchrist; Archie Bleyer
Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study.
Blood 1998;92(10):3569-77.
1998: Stacey L Berg; Daryl J Murry; Cynthia McCully; Karen Godwin; FRANK BALIS
Pharmacokinetics of O6-benzylguanine and its active metabolite 8-oxo-O6-benzylguanine in plasma and cerebrospinal fluid after intrathecal administration of O6-benzylguanine in the nonhuman primate.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2891-4.
1998: BU Mueller; B D Anderson; M Q Farley; R Murphy; J Zuckerman; Paul F Jarosinski; Karen Godwin; Cynthia McCully; Hiroaki Mitsuya; PA Pizzo; FRANK BALIS
Pharmacokinetics of the protease inhibitor KNI-272 in plasma and cerebrospinal fluid in nonhuman primates after intravenous dosing and in human immunodeficiency virus-infected children after intravenous and oral dosing.
Antimicrobial agents and chemotherapy 1998;42(7):1815-8.
1998: BU Mueller; John W Sleasman; RP Nelson; S Smith; Paul J Deutsch; W Ju; Seth M Steinberg; FRANK BALIS; Paul F Jarosinski; Pim Brouwers; Goutam C Mistry; Gregory A Winchell; Sheryl Zwerski; Shizuko Sei; Lauren V Wood; Steven L Zeichner; PA Pizzo
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
Pediatrics 1998;102(1 Pt 1):101-9.
1998: BU Mueller; RP Nelson; John W Sleasman; J Zuckerman; M Heath-Chiozzi; Seth M Steinberg; FRANK BALIS; Pim Brouwers; Ann Hsu; R Saulis; Shizuko Sei; Lauren V Wood; Steven L Zeichner; T T Katz; C Higham; D Aker; Maureen Edgerly; Paul F Jarosinski; L Serchuck; Scott M Whitcup; DJ Pizzuti; PA Pizzo
A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.
Pediatrics 1998;101(3 Pt 1):335-43.
1998: Susan M Blaney; Michael Neil Needle; Andrea Gillespie; J K Sato; Gregory H Reaman; Stacey L Berg; Peter Charles Adamson; Mark Krailo; Archie Bleyer; David G Poplack; FRANK BALIS
Phase II trial of topotecan administered as 72-hour continuous infusion in children with refractory solid tumors: a collaborative Pediatric Branch, National Cancer Institute, and Children's Cancer Group Study.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):357-60.
1998: Susan M Blaney; C Takimoto; Daryl J Murry; Nancy Kuttesch; Cynthia McCully; D E Cole; Karen Godwin; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates.
Cancer chemotherapy and pharmacology 1998;41(6):464-8.
1998: Stacey L Berg; Susan M Blaney; Peter Charles Adamson; Michelle O'Brien; David G Poplack; Carola A S Arndt; Julie Blatt; FRANK BALIS
Phase I trial and pharmacokinetic study of pyrazoloacridine in children and young adults with refractory cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(1):181-6.
1997: S L Driscoll; Mary E Hawkins; FRANK BALIS; W Pfleiderer; William R Laws
Fluorescence properties of a new guanosine analog incorporated into small oligonucleotides.
Biophysical journal 1997;73(6):3277-86.
1997: Peter Charles Adamson; Gregory Reaman; Jerry Z Finklestein; James Feusner; Stacey L Berg; Susan M Blaney; Michelle O'Brien; RF Murphy; FRANK BALIS
Phase I trial and pharmacokinetic study of all-trans-retinoic acid administered on an intermittent schedule in combination with interferon-alpha2a in pediatric patients with refractory cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(11):3330-7.
1997: Jean L Grem; N McAtee; RF Murphy; FRANK BALIS; E Cullen; Alice P Chen; J Michael Hamilton; Seth M Steinberg; Mary Quinn; JM Sorensen; Arbuck Susan; D Lawrence; Janet Pang; Carmen J Allegra
A pilot study of gamma-1b-interferon in combination with fluorouracil, leucovorin, and alpha-2a-interferon.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1125-34.
1997: Brenda Joyce Kitchen; FRANK BALIS; David G Poplack; Michelle O'Brien; C E Craig; Peter Charles Adamson
A pediatric phase I trial and pharmacokinetic study of thioguanine administered by continuous i.v. infusion.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):713-7.
1997: BRIGITTE WIDEMANN; FRANK BALIS; RF Murphy; JM Sorensen; MJ Montello; Michelle O'Brien; Peter Charles Adamson
Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):2125-34.
1997: Susan M Blaney; Nita L Seibel; Michelle O'Brien; Gregory H Reaman; Stacey L Berg; Peter Charles Adamson; David G Poplack; Mark Krailo; Revonda B Mosher; FRANK BALIS
Phase I trial of docetaxel administered as a 1-hour infusion in children with refractory solid tumors: a collaborative pediatric branch, National Cancer Institute and Children's Cancer Group trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(4):1538-43.
1997: Mary E Hawkins; W Pfleiderer; FRANK BALIS; D Porter; Jay R Knutson
Fluorescence properties of pteridine nucleoside analogs as monomers and incorporated into oligonucleotides.
Analytical biochemistry 1997;244(1):86-95.
1996: Leonard H Wexler; T F DeLaney; Maria Tsokos; Nilo A Avila; Seth M Steinberg; L Weaver-McClure; J Jacobson; Paul F Jarosinski; Yasmine Hijazi; FRANK BALIS; M E Horowitz
Ifosfamide and etoposide plus vincristine, doxorubicin, and cyclophosphamide for newly diagnosed Ewing's sarcoma family of tumors.
Cancer 1996;78(4):901-11.
1996: Susan M Blaney; Peter C Phillips; R J Packer; Richard L Heideman; Stacey L Berg; Peter Charles Adamson; J C Allen; Stephen E Sallan; R I Jakacki; Beverly J Lange; Gregory H Reaman; M E Horowitz; David G Poplack; FRANK BALIS
Phase II evaluation of topotecan for pediatric central nervous system tumors.
Cancer 1996;78(3):527-31.
1996: L L Lewis; David Venzon; J Church; M Farley; S Wheeler; A Keller; M Rubin; G Yuen; B Mueller; M Sloas; L Wood; FRANK BALIS; Gene M Shearer; Pim Brouwers; J Goldsmith; PA Pizzo
Lamivudine in children with human immunodeficiency virus infection: a phase I/II study. The National Cancer Institute Pediatric Branch-Human Immunodeficiency Virus Working Group.
The Journal of infectious diseases 1996;174(1):16-25.
1996: Jean L Grem; P M Politi; S L Berg; N M Benchekroun; M Patel; FRANK BALIS; B K Sinha; William Dahut; Carmen J Allegra
Cytotoxicity and DNA damage associated with pyrazoloacridine in MCF-7 breast cancer cells.
Biochemical pharmacology 1996;51(12):1649-59.
1996: A W Tolcher; Kenneth H Cowan; D Solomon; Frederick P Ognibene; Barry Goldspiel; R Chang; MH Noone; A M Denicoff; C S Barnes; M R Gossard; Patricia A Fetsch; Stacey L Berg; FRANK BALIS; D J Venzon; Joyce A O'Shaughnessy
Phase I crossover study of paclitaxel with r-verapamil in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(4):1173-84.
1996: J S Fisherman; Kenneth H Cowan; MH Noone; A Denicoff; S Berg; David G Poplack; FRANK BALIS; David Venzon; M McCabe; Barry Goldspiel; Catherine Chow; Frederick P Ognibene; Joyce A O'Shaughnessy
Phase I/II study of 72-hour infusional paclitaxel and doxorubicin with granulocyte colony-stimulating factor in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(3):774-82.
1996: Leonard H Wexler; M P Andrich; David Venzon; Stacey L Berg; L Weaver-McClure; Clara C Chen; Vasken Dilsizian; Nilo A Avila; Paul F Jarosinski; FRANK BALIS; David G Poplack; M E Horowitz
Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(2):362-72.
1996: J R Geyer; FRANK BALIS; Mark Krailo; R Heideman; E Broxson; J K Sato; David G Poplack; Archie Bleyer
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
Investigational new drugs 1996;13(4):337-42.
1995: P T Ho; K Zimmerman; Leonard H Wexler; Susan M Blaney; Paul F Jarosinski; L Weaver-McClure; Shai Izraeli; FRANK BALIS
A prospective evaluation of ifosfamide-related nephrotoxicity in children and young adults.
Cancer 1995;76(12):2557-64.
1995: Susan M Blaney; M J Daniel; A J Harker; Karen Godwin; FRANK BALIS
Pharmacokinetics of lamivudine and BCH-189 in plasma and cerebrospinal fluid of nonhuman primates.
Antimicrobial agents and chemotherapy 1995;39(12):2779-82.
1995: Stacey L Berg; S L Gerson; Karen Godwin; D E Cole; L Liu; FRANK BALIS
Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate.
Cancer research 1995;55(20):4606-10.
1995: Peter Charles Adamson; FRANK BALIS; J E Belasco; B Lange; Stacey L Berg; Susan M Blaney; C Craig; David G Poplack
A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer.
Cancer research 1995;55(18):4069-72.
1995: Mary E Hawkins; W Pfleiderer; A Mazumder; Yves Pommier; FRANK BALIS
Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction.
Nucleic acids research 1995;23(15):2872-80.
1995: BRIGITTE WIDEMANN; M L Hetherington; RF Murphy; FRANK BALIS; Peter Charles Adamson
Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity.
Cancer 1995;76(3):521-6.
1995: Stacey L Berg; A Tolcher; Joyce A O'Shaughnessy; A M Denicoff; MH Noone; Frederick P Ognibene; Kenneth H Cowan; FRANK BALIS
Effect of R-verapamil on the pharmacokinetics of paclitaxel in women with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(8):2039-42.
1995: Wyndham H Wilson; CA Jamis-Dow; G Bryant; FRANK BALIS; Raymond W Klecker; Susan E Bates; B A Chabner; Seth M Steinberg; David R Kohler; Robert Wittes
Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(8):1985-94.
1995: Mary E Hawkins; Hiroaki Mitsuya; C M McCully; K S Godwin; K Murakami; David G Poplack; FRANK BALIS
Pharmacokinetics of dideoxypurine nucleoside analogs in plasma and cerebrospinal fluid of rhesus monkeys.
Antimicrobial agents and chemotherapy 1995;39(6):1259-64.
1995: Peter Charles Adamson; J Bailey; James M Pluda; David G Poplack; S Bauza; RF Murphy; Robert Yarchoan; FRANK BALIS
Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(5):1238-41.
1995: R A Smith; FRANK BALIS; K H Ott; D D Elsberry; M R Sherman; M G Saifer
Pharmacokinetics and tolerability of ventricularly administered superoxide dismutase in monkeys and preliminary clinical observations in familial ALS.
Journal of the neurological sciences 1995;129 Suppl():13-8.
1995: K S Godwin; Cynthia McCully; David G Poplack; FRANK BALIS
An animal facility database management system using a Macintosh computer and commercially available software.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 1995;34(2):54-6.
1995: Peter Charles Adamson; RF Murphy; Karen Godwin; E H Ulm; FRANK BALIS
Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey.
Cancer research 1995;55(3):482-5.
1995: Susan M Blaney; David G Poplack; Karen Godwin; Cynthia McCully; R Murphy; FRANK BALIS
Effect of body position on ventricular CSF methotrexate concentration following intralumbar administration.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(1):177-9.
1995: Susan M Blaney; D E Cole; Karen Godwin; Cynthia Sung; David G Poplack; FRANK BALIS
Intrathecal administration of topotecan in nonhuman primates.
Cancer chemotherapy and pharmacology 1995;36(2):121-4.
1994: Peter Charles Adamson; David G Poplack; FRANK BALIS
The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia.
Leukemia research 1994;18(11):805-10.
1994: BU Mueller; K M Butler; V L Stocker; FRANK BALIS; Pim Brouwers; Paul F Jarosinski; R N Husson; L L Lewis; David Venzon; PA Pizzo
Clinical and pharmacokinetic evaluation of long-term therapy with didanosine in children with HIV infection.
Pediatrics 1994;94(5):724-31.
1994: Cynthia Sung; Susan M Blaney; D E Cole; FRANK BALIS; Robert L Dedrick
A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid.
Cancer research 1994;54(19):5118-22.
1994: Shai Izraeli; Peter Charles Adamson; Susan M Blaney; FRANK BALIS
Acute pancreatitis after ifosfamide therapy.
Cancer 1994;74(5):1627-8.
1994: George L Drusano; FRANK BALIS; S R Gitterman; P A Pizzo
Quantitative relationships between zidovudine exposure and efficacy and toxicity.
Antimicrobial agents and chemotherapy 1994;38(8):1726-31.
1994: J D Bacher; FRANK BALIS; Cynthia McCully; K S Godwin
Cerebral subarachnoid sampling of cerebrospinal fluid in the rhesus monkey.
Laboratory animal science 1994;44(2):148-52.
1994: S Berg; FRANK BALIS; Cynthia McCully; David G Poplack
Re: Toxicity of intrathecal melphalan.
Journal of the National Cancer Institute 1994;86(6):463.
1994: Jean L Grem; N McAtee; RF Murphy; J Michael Hamilton; FRANK BALIS; S Steinberg; Arbuck Susan; A Setser; E Jordan; A Chen
Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony-stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(3):560-8.
1994: R N Husson; BU Mueller; M Farley; L Woods; A Kovacs; J C Goldsmith; J Ono; L L Lewis; FRANK BALIS; Pim Brouwers
Zidovudine and didanosine combination therapy in children with human immunodeficiency virus infection.
Pediatrics 1994;93(2):316-22.
1994: Stacey L Berg; Kenneth H Cowan; FRANK BALIS; J S Fisherman; A M Denicoff; M Hillig; David G Poplack; Joyce A O'Shaughnessy
Pharmacokinetics of taxol and doxorubicin administered alone and in combination by continuous 72-hour infusion.
Journal of the National Cancer Institute 1994;86(2):143-5.
1993: Peter Charles Adamson; FRANK BALIS; Mary E Hawkins; RF Murphy; David G Poplack
Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells.
Biochemical pharmacology 1993;46(9):1627-36.
1993: Stacey L Berg; FRANK BALIS; K S Godwin; David G Poplack
Pharmacokinetics, cerebrospinal fluid penetration, and metabolism of piroxantrone in the rhesus monkey.
Investigational new drugs 1993;11(4):255-61.
1993: Jean L Grem; N McAtee; Seth M Steinberg; J Michael Hamilton; RF Murphy; J Drake; T Chisena; FRANK BALIS; R Cysyk; Arbuck Susan
A phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma.
Cancer research 1993;53(20):4828-36.
1993: D M Savarese; A M Denicoff; Stacey L Berg; M Hillig; Stephen Baker; Joyce A O'Shaughnessy; Catherine Chow; GA Otterson; FRANK BALIS; David G Poplack
Phase I study of high-dose piroxantrone with granulocyte colony-stimulating factor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(9):1795-803.
1993: Jean L Grem; N McAtee; FRANK BALIS; R Murphy; David Venzon; B Kramer; Barry Goldspiel; M Begley; Carmen J Allegra
A phase II study of continuous infusion 5-fluorouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma.
Cancer 1993;72(3):663-8.
1993: Richard L Heideman; R J Packer; Gregory H Reaman; J C Allen; B Lange; M E Horowitz; Seth M Steinberg; A Gillespie; E H Kovnar; FRANK BALIS
A phase II evaluation of thiotepa in pediatric central nervous system malignancies.
Cancer 1993;72(1):271-5.
1993: Peter Charles Adamson; H C Pitot; FRANK BALIS; J Rubin; RF Murphy; David G Poplack
Variability in the oral bioavailability of all-trans-retinoic acid.
Journal of the National Cancer Institute 1993;85(12):993-6.
1993: Stacey L Berg; D M Savarese; FRANK BALIS; A M Denicoff; M Hillig; Joyce A O'Shaughnessy; David G Poplack; Kenneth H Cowan
Pharmacokinetics of piroxantrone in a phase I trial of piroxantrone and granulocyte-colony stimulating factor.
Cancer research 1993;53(11):2587-90.
1993: Richard L Heideman; Cynthia McCully; FRANK BALIS; David G Poplack
Cerebrospinal fluid pharmacokinetics and toxicology of intraventricular and intrathecal arabinosyl-5-azacytosine (fazarabine, NSC 281272) in the nonhuman primate.
Investigational new drugs 1993;11(2-3):135-40.
1993: Susan M Blaney; J L Grem; FRANK BALIS; D E Cole; Peter Charles Adamson; David G Poplack
Mechanism of resistance to cyclopentenyl cytosine (CPE-C) in Molt-4 lymphoblasts.
Biochemical pharmacology 1993;45(7):1493-501.
1993: G Rodriguez; T D Brown; FRANK BALIS; J B Craig; C A Denham; John Kuhn; K Havlin; Daniel Von Hoff
A phase I trial of trimetrexate (NSC352122) on a daily x 5 schedule in patients with refractory adult leukemia.
Anti-cancer drugs 1993;4(2):163-6.
1993: S Kim; S Khatibi; S B Howell; C McCully; FRANK BALIS; David G Poplack
Prolongation of drug exposure in cerebrospinal fluid by encapsulation into DepoFoam.
Cancer research 1993;53(7):1596-8.
1993: K M Butler; David Venzon; N Henry; R N Husson; BU Mueller; FRANK BALIS; F Jacobsen; L L Lewis; PA Pizzo
Pancreatitis in human immunodeficiency virus-infected children receiving dideoxyinosine.
Pediatrics 1993;91(4):747-51.
1993: Susan M Blaney; FRANK BALIS; D E Cole; C Craig; Joel M Reid; Matthew M Ames; Mark Krailo; Gregory Reaman; D Hammond; David G Poplack
Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion.
Cancer research 1993;53(5):1032-6.
1993: Susan M Blaney; D E Cole; FRANK BALIS; Karen Godwin; David G Poplack
Plasma and cerebrospinal fluid pharmacokinetic study of topotecan in nonhuman primates.
Cancer research 1993;53(4):725-7.
1993: Peter Charles Adamson; J F Boylan; FRANK BALIS; RF Murphy; Karen Godwin; L J Gudas; David G Poplack
Time course of induction of metabolism of all-trans-retinoic acid and the up-regulation of cellular retinoic acid-binding protein.
Cancer research 1993;53(3):472-6.
1993: Stacey L Berg; FRANK BALIS; Cynthia McCully; K S Godwin; David G Poplack
Pharmacokinetics of PEG-L-asparaginase and plasma and cerebrospinal fluid L-asparagine concentrations in the rhesus monkey.
Cancer chemotherapy and pharmacology 1993;32(4):310-4.
1992: Malcolm A Smith; Peter Charles Adamson; FRANK BALIS; J Feusner; L Aronson; RF Murphy; M E Horowitz; Gregory Reaman; G D Hammond; R M Fenton
Phase I and pharmacokinetic evaluation of all-trans-retinoic acid in pediatric patients with cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(11):1666-73.
1992: Peter Charles Adamson; FRANK BALIS; Malcolm A Smith; RF Murphy; Karen Godwin; David G Poplack
Dose-dependent pharmacokinetics of all-trans-retinoic acid.
Journal of the National Cancer Institute 1992;84(17):1332-5.
1992: Peter Charles Adamson; FRANK BALIS; Cynthia McCully; K S Godwin; David G Poplack
Methotrexate pharmacokinetics following administration of recombinant carboxypeptidase-G2 in rhesus monkeys.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(8):1359-64.
1992: Susan M Blaney; FRANK BALIS; J Grem; D E Cole; Peter Charles Adamson; David G Poplack
Modulation of the cytotoxic effect of cyclopentenylcytosine by its primary metabolite, cyclopentenyluridine.
Cancer research 1992;52(12):3503-5.
1992: Jean L Grem; Edward Chu; D Boarman; FRANK BALIS; RF Murphy; N McAtee; Carmen J Allegra
Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations.
Seminars in oncology 1992;19(2 Suppl 3):36-44.
1992: Peter Charles Adamson; FRANK BALIS; J Miser; Carola A S Arndt; R J Wells; A Gillespie; L Aronson; J S Penta; N J Clendeninn; David G Poplack
Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule.
Cancer research 1992;52(3):521-4.
1992: Stacey L Berg; FRANK BALIS; S Zimm; RF Murphy; J Holcenberg; J Sato; Gregory Reaman; Peter G Steinherz; A Gillespie; K Doherty
Phase I/II trial and pharmacokinetics of intrathecal diaziquone in refractory meningeal malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(1):143-8.
1992: FRANK BALIS; PA Pizzo; K M Butler; Mary E Hawkins; Pim Brouwers; R N Husson; F Jacobsen; Susan M Blaney; J Gress; Paul F Jarosinski
Clinical pharmacology of 2',3'-dideoxyinosine in human immunodeficiency virus-infected children.
The Journal of infectious diseases 1992;165(1):99-104.
1992: Peter Charles Adamson; S Zimm; A H Ragab; FRANK BALIS; Seth M Steinberg; Barton A. Kamen; Teresa J Vietti; A Gillespie; David G Poplack
A phase II trial of continuous-infusion 6-mercaptopurine for childhood leukemia.
Cancer chemotherapy and pharmacology 1992;30(2):155-7.
1992: Stacey L Berg; FRANK BALIS; Cynthia McCully; G A Parker; RF Murphy; David G Poplack
Intrathecal 5-fluorouracil in the rhesus monkey.
Cancer chemotherapy and pharmacology 1992;31(2):127-30.
1991: Peter Charles Adamson; FRANK BALIS; Carola A S Arndt; J S Holcenberg; P K Narang; RF Murphy; A J Gillespie; David G Poplack
Intrathecal 6-mercaptopurine: preclinical pharmacology, phase I/II trial, and pharmacokinetic study.
Cancer research 1991;51(22):6079-83.
1991: FRANK BALIS; Susan M Blaney; David G Poplack
Antiretroviral drug development and clinical pharmacology.
The Pediatric infectious disease journal 1991;10(11):849-57.
1991: Stacey L Berg; FRANK BALIS; Cynthia McCully; K S Godwin; David G Poplack
Pharmacokinetics of pyrazoloacridine in the rhesus monkey.
Cancer research 1991;51(20):5467-70.
1991: Jean L Grem; N McAtee; RF Murphy; FRANK BALIS; Seth M Steinberg; J Michael Hamilton; JM Sorensen; Oliver Sartor; B S Kramer; L J Goldstein
A pilot study of interferon alfa-2a in combination with fluorouracil plus high-dose leucovorin in metastatic gastrointestinal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(10):1811-20.
1991: Susan M Blaney; FRANK BALIS; David G Poplack
Pharmacologic approaches to the treatment of meningeal malignancy.
Oncology (Williston Park, N.Y.) 1991;5(5):107-16; discussion 123, 127.
1991: Susan M Blaney; FRANK BALIS; David G Poplack
Current pharmacological treatment approaches to central nervous system leukaemia.
Drugs 1991;41(5):702-16.
1991: Peter Charles Adamson; FRANK BALIS; Cynthia McCully; K S Godwin; J D Bacher; THOMAS WALSH; David G Poplack
Rescue of experimental intrathecal methotrexate overdose with carboxypeptidase-G2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(4):670-4.
1991: Stacey L Berg; D L Grisell; T F DeLaney; FRANK BALIS
Principles of treatment of pediatric solid tumors.
Pediatric clinics of North America 1991;38(2):249-67.
1991: K M Butler; R N Husson; FRANK BALIS
Drug trial benefited HIV children.
Nursing times 1991;87(5):10.
1991: K M Butler; R N Husson; FRANK BALIS; Pim Brouwers; J Eddy; D el-Amin; J Gress; M Hawkins; Paul F Jarosinski; H Moss
Dideoxyinosine in children with symptomatic human immunodeficiency virus infection.
The New England journal of medicine 1991;324(3):137-44.
1990: Susan M Blaney; FRANK BALIS; L Hegedus; Richard L Heideman; Cynthia McCully; RF Murphy; James A Kelley; David G Poplack
Pharmacokinetics and metabolism of cyclopentenyl cytosine in nonhuman primates.
Cancer research 1990;50(24):7915-9.
1990: Pim Brouwers; H Moss; Pamela L Wolters; J Eddy; FRANK BALIS; David G Poplack; PA Pizzo
Effect of continuous-infusion zidovudine therapy on neuropsychologic functioning in children with symptomatic human immunodeficiency virus infection.
The Journal of pediatrics 1990;117(6):980-5.
1990: Peter Charles Adamson; FRANK BALIS; S M Steinberg; David G Poplack; J S Holcenberg
Pharmacokinetics of mercaptopurine in children with acute lymphocytic leukemia.
The New England journal of medicine 1990;323(22):1565-6.
1990: M E Hawkins; David G Poplack; P A Pizzo; FRANK BALIS
High-performance liquid chromatographic method for the analysis of 2',3'-dideoxycytidine in human plasma.
Journal of chromatography 1990;532(2):442-4.
1990: PA Pizzo; K Butler; FRANK BALIS; E Brouwers; M Hawkins; J Eddy; M Einloth; Judith Falloon; R Husson; Paul F Jarosinski
Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection.
The Journal of pediatrics 1990;117(5):799-808.
1990: Peter Charles Adamson; David G Poplack; FRANK BALIS
Pharmacology and drug resistance in childhood lymphoblastic leukemia.
Hematology/oncology clinics of North America 1990;4(5):871-94.
1990: Cynthia McCully; FRANK BALIS; John Bacher; J Phillips; David G Poplack
A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid.
Laboratory animal science 1990;40(5):520-5.
1990: Peter Charles Adamson; FRANK BALIS; J Miser; R J Wells; Archie Bleyer; T E Williams; A Gillespie; J S Penta; N J Clendeninn; David G Poplack
Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule.
Cancer research 1990;50(15):4464-7.
1990: THOMAS WALSH; C Lester-McCully; Michael G Rinaldi; J E Wallace; FRANK BALIS; J W Lee; PA Pizzo; David G Poplack
Penetration of SCH-39304, a new antifungal triazole, into cerebrospinal fluid of primates.
Antimicrobial agents and chemotherapy 1990;34(6):1281-4.
1990: FRANK BALIS; A Gillespie; J Belasco; Gregory H Reaman; L J Ettinger; RF Murphy; K Doherty; S Jeffries; M E Horowitz; David G Poplack
Phase II trial of sequential methotrexate and 5-fluorouracil with leucovorin in children with sarcomas.
Investigational new drugs 1990;8(2):181-2.
1990: Carmen J Allegra; J Jenkins; Raymond B Weiss; FRANK BALIS; J C Drake; J Brooks; R Thomas; G A Curt
A phase I and pharmacokinetic study of trimetrexate using a 24-hour continuous-injection schedule.
Investigational new drugs 1990;8(2):159-66.
1990: M E Carpen; David G Poplack; PA Pizzo; FRANK BALIS
High-performance liquid chromatographic method for analysis of 2',3'-dideoxyinosine in human body fluids.
Journal of chromatography 1990;526(1):69-75.
1990: Peter Charles Adamson; S Zimm; A H Ragab; Seth M Steinberg; FRANK BALIS; Barton A. Kamen; Teresa J Vietti; A Gillespie; David G Poplack
A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors.
Cancer chemotherapy and pharmacology 1990;26(5):343-4.
1989: Richard L Heideman; A Gillespie; Harry Ford; Gregory H Reaman; FRANK BALIS; C Tan; J Sato; L J Ettinger; R J Packer; David G Poplack
Phase I trial and pharmacokinetic evaluation of fazarabine in children.
Cancer research 1989;49(18):5213-6.
1989: M L Rothenberg; Lyn A Mickley; D E Cole; FRANK BALIS; T Tsuruo; David G Poplack; Antonio Tito Fojo
Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia.
Blood 1989;74(4):1388-95.
1989: FRANK BALIS; Cynthia McCully; L Gough; PA Pizzo; David G Poplack
Pharmacokinetics of subcutaneous azidothymidine in rhesus monkeys.
Antimicrobial agents and chemotherapy 1989;33(6):810-2.
1989: FRANK BALIS; PA Pizzo; J Eddy; C Wilfert; R McKinney; Gwendolyn B Scott; R F Murphy; Paul F Jarosinski; Judith Falloon; David G Poplack
Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.
The Journal of pediatrics 1989;114(5):880-4.
1989: FRANK BALIS; PA Pizzo; R F Murphy; J Eddy; Paul F Jarosinski; Judith Falloon; S Broder; David G Poplack
The pharmacokinetics of zidovudine administered by continuous infusion in children.
Annals of internal medicine 1989;110(4):279-85.
1989: R Goel; S M Cleary; C Horton; FRANK BALIS; S Zimm; S Kirmani; Stephen B Howell
Selective intraperitoneal biochemical modulation of methotrexate by dipyridamole.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(2):262-9.
1989: Richard L Heideman; D E Cole; FRANK BALIS; J Sato; Gregory H Reaman; R J Packer; L J Singher; L J Ettinger; A Gillespie; J Sam
Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa.
Cancer research 1989;49(3):736-41.
1989: FRANK BALIS; S L Jeffries; B Lange; RF Murphy; K M Doherty; Carola A S Arndt; N Luery; David G Poplack
Chronopharmacokinetics of oral methotrexate and 6-mercaptopurine: is there diurnal variation in the disposition of antileukemic therapy?
The American journal of pediatric hematology/oncology 1989;11(3):324-6.
1989: FRANK BALIS; David G Poplack
Central nervous system pharmacology of antileukemic drugs.
The American journal of pediatric hematology/oncology 1989;11(1):74-86.
1988: FRANK BALIS; J Mirro; Gregory H Reaman; William Evans; Cynthia McCully; K M Doherty; RF Murphy; S Jeffries; David G Poplack
Pharmacokinetics of subcutaneous methotrexate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(12):1882-6.
1988: PA Pizzo; J Eddy; Judith Falloon; FRANK BALIS; R F Murphy; H Moss; Pamela L Wolters; Pim Brouwers; Paul F Jarosinski; M Rubin
Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection.
The New England journal of medicine 1988;319(14):889-96.
1988: N Ramu; A Ramu; D E Cole; FRANK BALIS; David G Poplack; H B Pollard
Mechanism of acquired resistance to methotrexate in P388 murine leukemia cells and in their doxorubicin-resistant subline.
Israel journal of medical sciences 1988;24(9-10):477-82.
1988: FRANK BALIS
Pharmacologic considerations in the treatment of acute lymphoblastic leukemia.
Pediatric clinics of North America 1988;35(4):835-51.
1988: Richard L Heideman; FRANK BALIS; Cynthia McCully; David G Poplack
Preclinical pharmacology of arabinosyl-5-azacytidine in nonhuman primates.
Cancer research 1988;48(15):4294-8.
1988: Paul F Jarosinski; Jeffrey A Moscow; M S Alexander; L J Lesko; FRANK BALIS; David G Poplack
Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia.
The Journal of pediatrics 1988;112(6):996-9.
1988: J M Collins; Raymond W Klecker; James A Kelley; JS Roth; Cynthia McCully; FRANK BALIS; David G Poplack
Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid.
The Journal of pharmacology and experimental therapeutics 1988;245(2):466-70.
1988: Carola A S Arndt; FRANK BALIS; Cynthia McCully; S L Jeffries; K Doherty; R Murphy; David G Poplack
Bioavailability of low-dose vs high-dose 6-mercaptopurine.
Clinical pharmacology and therapeutics 1988;43(5):588-91.
1988: Richard L Heideman; James A Kelley; R J Packer; Gregory H Reaman; JS Roth; FRANK BALIS; L J Ettinger; K M Doherty; S L Jeffries; David G Poplack
A pediatric phase I and pharmacokinetic study of spirohydantoin mustard.
Cancer research 1988;48(8):2292-5.
1988: Carola A S Arndt; FRANK BALIS; Cynthia McCully; O M Colvin; David G Poplack
Cerebrospinal fluid penetration of active metabolites of cyclophosphamide and ifosfamide in rhesus monkeys.
Cancer research 1988;48(8):2113-5.
1988: P Rogers; Carmen J Allegra; R F Murphy; J C Drake; Henry Masur; David G Poplack; B A Chabner; J E Parrillo; H Clifford Lane; FRANK BALIS
Bioavailability of oral trimetrexate in patients with acquired immunodeficiency syndrome.
Antimicrobial agents and chemotherapy 1988;32(3):324-6.
1988: Carola A S Arndt; THOMAS WALSH; Cynthia McCully; FRANK BALIS; PA Pizzo; David G Poplack
Fluconazole penetration into cerebrospinal fluid: implications for treating fungal infections of the central nervous system.
The Journal of infectious diseases 1988;157(1):178-80.
1987: R F Murphy; FRANK BALIS; David G Poplack
Stability of 5-fluorouracil in whole blood and plasma.
Clinical chemistry 1987;33(12):2299-300.
1987: Carola A S Arndt; O M Colvin; FRANK BALIS; C M Lester; G Johnson; David G Poplack
Intrathecal administration of 4-hydroperoxycyclophosphamide in rhesus monkeys.
Cancer research 1987;47(22):5932-4.
1987: Carmen J Allegra; B A Chabner; C U Tuazon; D Ogata-Arakaki; B Baird; J C Drake; J T Simmons; E E Lack; James H Shelhamer; FRANK BALIS
Trimetrexate for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome.
The New England journal of medicine 1987;317(16):978-85.
1987: FRANK BALIS; R Patel; E Luks; K M Doherty; J S Holcenberg; C Tan; Gregory H Reaman; J Belasco; L J Ettinger; S Zimm
Pediatric phase I trial and pharmacokinetic study of trimetrexate.
Cancer research 1987;47(18):4973-6.
1987: R F Greene; A W Miser; C M Lester; FRANK BALIS; David G Poplack
Cerebrospinal fluid and plasma pharmacokinetics of morphine infusions in pediatric cancer patients and rhesus monkeys.
Pain 1987;30(3):339-48.
1987: James A Kelley; C L Litterst; JS Roth; D T Vistica; David G Poplack; D A Cooney; M Nadkarni; FRANK BALIS; S Broder; David G Johns
The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys.
Drug metabolism and disposition: the biological fate of chemicals 1987;15(5):595-601.
1987: FRANK BALIS; J S Holcenberg; S Zimm; DG Tubergen; J M Collins; RF Murphy; G S Gilchrist; D Hammond; David G Poplack
The effect of methotrexate on the bioavailability of oral 6-mercaptopurine.
Clinical pharmacology and therapeutics 1987;41(4):384-7.
1987: FRANK BALIS; C M Lester; G P Chrousos; R L Heideman; David G Poplack
Differences in cerebrospinal fluid penetration of corticosteroids: possible relationship to the prevention of meningeal leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(2):202-7.
1987: N J Winick; Barton A. Kamen; FRANK BALIS; J Holcenberg; C M Lester; David G Poplack
Folate and methotrexate polyglutamate tissue levels in rhesus monkeys following chronic low-dose methotrexate.
Cancer drug delivery 1987;4(1):25-31.
1986: David G Poplack; FRANK BALIS; S Zimm
The pharmacology of orally administered chemotherapy. A reappraisal.
Cancer 1986;58(2 Suppl):473-80.
1986: FRANK BALIS
Pharmacokinetic drug interactions of commonly used anticancer drugs.
Clinical pharmacokinetics 1986;11(3):223-35.
1986: FRANK BALIS; R F Murphy; C M Lester; David G Poplack
The influence of route of administration on the hepatic uptake of methotrexate.
Cancer drug delivery 1986;3(4):239-42.
1986: R L Heideman; FRANK BALIS; S Zimm; C M Lester; David G Poplack
The effect of amitriptyline on the central nervous system penetration of methotrexate.
Cancer drug delivery 1986;3(4):219-22.
1986: Riccardo Riccardi; FRANK BALIS; P Ferrara; Anna Lasorella; David G Poplack; Renato Mastrangelo
Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.
Pediatric hematology and oncology 1986;3(4):319-24.
1986: FRANK BALIS; C M Lester; David G Poplack
Pharmacokinetics of trimetrexate (NSC 352122) in monkeys.
Cancer research 1986;46(1):169-74.
1985: FRANK BALIS; Beverly J Lange; R J Packer; J S Holcenberg; L J Ettinger; Stephen E Sallan; R L Heideman; S Zimm; W A Smithson; N A Cogliano-Shutta
Pediatric phase I trial and pharmacokinetic study of tiazofurin (NSC 286193).
Cancer research 1985;45(10):5169-72.
1985: J J Grygiel; FRANK BALIS; J M Collins; C M Lester; David G Poplack
Pharmacokinetics of tiazofurin in the plasma and cerebrospinal fluid of rhesus monkeys.
Cancer research 1985;45(5):2037-9.
1985: S Zimm; L J Ettinger; J S Holcenberg; Barton A. Kamen; Teresa J Vietti; J Belasco; N Cogliano-Shutta; FRANK BALIS; L E Lavi; J M Collins
Phase I and clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion.
Cancer research 1985;45(4):1869-73.
1985: FRANK BALIS; J L Savitch; W A Bleyer; G H Reaman; David G Poplack
Remission induction of meningeal leukemia with high-dose intravenous methotrexate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(4):485-9.
1985: M Morse; J Savitch; FRANK BALIS; J Miser; J Feusner; Gregory Reaman; David G Poplack; A Bleyer
Altered central nervous system pharmacology of methotrexate in childhood leukemia: another sign of meningeal relapse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(1):19-24.
1983: FRANK BALIS; J L Savitch; W A Bleyer
Pharmacokinetics of oral methotrexate in children.
Cancer research 1983;43(5):2342-5.
1983: FRANK BALIS; J S Holcenberg; W A Bleyer
Clinical pharmacokinetics of commonly used anticancer drugs.
Clinical pharmacokinetics 1983;8(3):202-32.
1982: F L Johnson; FRANK BALIS
Hepatopathy following irradiation and chemotherapy for Wilms' tumor.
The American journal of pediatric hematology/oncology 1982;4(2):217-21.