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Shekhar Srivastava

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Olga Zhdanova; Shekhar Srivastava; Leila Tchelebi; Jiri Zavadil; Laura Barisoni; Mark M Chong; Lie Di; Sara Dworkin; Lawrence B Holzman; Duncan B Johnstone; Zhai Li; Dan R Littman; Edward Y Skolnik
The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.
Lie Di; Shekhar Srivastava; Olga Zhdanova; Yi Ding; Zhai Li; Heike Wulff; Maria Lafaille; Edward Y Skolnik
Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis.
Shekhar Srivastava; Lie Di; Olga Zhdanova; Zhai Li; Santosha Vardhana; Qi Wan; Ying Yan; Rajat Varma; Jonathan M Backer; Heike Wulff; Michael L Dustin; Edward Y Skolnik
The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.

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All Publications

2011: Olga Zhdanova; Shekhar Srivastava; Leila Tchelebi; Jiri Zavadil; Laura Barisoni; Mark M Chong; Lie Di; Sara Dworkin; Lawrence B Holzman; Duncan B Johnstone; Zhai Li; Dan R Littman; Edward Y Skolnik
The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.
Kidney international 2011;80(7):719-30.
2010: Lie Di; Shekhar Srivastava; Olga Zhdanova; Yi Ding; Zhai Li; Heike Wulff; Maria Lafaille; Edward Y Skolnik
Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1541-6.
2009: Shekhar Srivastava; Lie Di; Olga Zhdanova; Zhai Li; Santosha Vardhana; Qi Wan; Ying Yan; Rajat Varma; Jonathan M Backer; Heike Wulff; Michael L Dustin; Edward Y Skolnik
The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.
Molecular biology of the cell 2009;20(17):3783-91.
2008: Shekhar Srivastava; Olga Zhdanova; Lie Di; Zhai Li; Mamdouh Albaqumi; Heike Wulff; Edward Y Skolnik
Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K+ channel KCa3.1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14442-6.
2008: Mamdouh Albaqumi; Shekhar Srivastava; Zhai Li; Olga Zhdnova; Heike Wulff; Omar Itani; Darren P Wallace; Edward Y Skolnik
KCa3.1 potassium channels are critical for cAMP-dependent chloride secretion and cyst growth in autosomal-dominant polycystic kidney disease.
Kidney international 2008;74(6):740-9.
2007: Leon Collis; Shekhar Srivastava; William A Coetzee; Michael Artman
beta2-Adrenergic receptor agonists stimulate L-type calcium current independent of PKA in newborn rabbit ventricular myocytes.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2826-35.
2007: Shekhar Srivastava; Steven E Cala; William A Coetzee; Michael Artman
Phospholemman expression is high in the newborn rabbit heart and declines with postnatal maturation.
Biochemical and biophysical research communications 2007;355(2):338-41.
2006: Shekhar Srivastava; Zhai Li; Kyung Ko; Papiya Choudhury; Mamdouh Albaqumi; Amanda K Johnson; Ying Yan; Jonathan M Backer; Derya Unutmaz; William A Coetzee; Edward Y Skolnik
Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.
Molecular cell 2006;24(5):665-75.
2006: Papiya Choudhury; Shekhar Srivastava; Zhai Li; Kyung Ko; Mamdouh Albaqumi; Kartik Narayan; William A Coetzee; Mark A Lemmon; Edward Y Skolnik
Specificity of the myotubularin family of phosphatidylinositol-3-phosphatase is determined by the PH/GRAM domain.
The Journal of biological chemistry 2006;281(42):31762-9.
2006: Shekhar Srivastava; Kyung Ko; Papiya Choudhury; Zhai Li; Amanda K Johnson; Vivek Nadkarni; Derya Unutmaz; William A Coetzee; Edward Y Skolnik
Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells.
Molecular and cellular biology 2006;26(15):5595-602.
2006: XiaoYong Tong; Lisa M Porter; GongXin Liu; Piyali Dhar Chowdhury; Shekhar Srivastava; David J Pountney; Hidetada Yoshida; Michael Artman; Glenn I Fishman; Cindy Yu; Ramesh Iyer; Gregory E Morley; David E Gutstein; William A Coetzee
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.
American journal of physiology. Heart and circulatory physiology 2006;291(2):H543-51.
2006: Shekhar Srivastava; Papiya Choudhury; Zhai Li; Gongxin Liu; Vivek Nadkarni; Kyung Ko; William A Coetzee; Edward Y Skolnik
Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1.
Molecular biology of the cell 2006;17(1):146-54.
2005: Piyali Dhar Chowdhury; Maddison D Harrell; Sandra Y Han; Danuta Jankowska; Lavanya Parachuru; Alison Morrissey; Shekhar Srivastava; Weixia Liu; Brian Malester; Hidetada Yoshida; William A Coetzee
The glycolytic enzymes, glyceraldehyde-3-phosphate dehydrogenase, triose-phosphate isomerase, and pyruvate kinase are components of the K(ATP) channel macromolecular complex and regulate its function.
The Journal of biological chemistry 2005;280(46):38464-70.
2005: Shekhar Srivastava; Zhai Li; Lin Lin; GongXin Liu; Kyung Ko; William A Coetzee; Edward Y Skolnik
The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1.
Molecular and cellular biology 2005;25(9):3630-8.
2005: Anita Go; Shekhar Srivastava; Leon Collis; William A Coetzee; Michael Artman
Negative inotropic effect of nifedipine in the immature rabbit heart is due to shortening of the action potential.
Pediatric research 2005;57(3):399-403.
2005: Shekhar Srivastava; Leon Collis; Anita Go; Salvatore Mancarella; William A Coetzee; Michael Artman
Paradoxical effect of dofetilide on action potential duration and calcium transient amplitude in newborn rabbit ventricular myocytes.
Journal of cardiovascular pharmacology 2005;45(2):165-74.
2000: M Ray; Shekhar Srivastava; S C Maitra; M P Dubey
The hamster heart is resistant to calcium paradox.
Pharmacological research : the official journal of the Italian Pharmacological Society 2000;41(4):475-81.