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Elangovan Gopal

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Maciej P Mazurek; Puttur D Prasad; Elangovan Gopal; Scott P Fraser; Leszek Bolt; Nahit Rizaner; Christopher P Palmer; Christopher S Foster; Ferdinando Palmieri; Vadivel Ganapathy; Walter Stühmer; Mustafa B A Djamgoz; Maria E Mycielska
Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells.
Seiji Miyauchi; Elangovan Gopal; Ellappan Babu; Sonne R Srinivas; Yoshiyuki Kubo; Umapathy Siddaramappa; Santoshanand V Thakkar; Vadivel Ganapathy; Puttur D Prasad
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
Sudha Ananth; Lina Zhuang; Elangovan Gopal; Shiro Itagaki; Babu Ellappan; Sylvia B Smith; Vadivel Ganapathy; Pamela Moore Martin
Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon.

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All Publications

2010: Maciej P Mazurek; Puttur D Prasad; Elangovan Gopal; Scott P Fraser; Leszek Bolt; Nahit Rizaner; Christopher P Palmer; Christopher S Foster; Ferdinando Palmieri; Vadivel Ganapathy; Walter Stühmer; Mustafa B A Djamgoz; Maria E Mycielska
Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells.
EMBO reports 2010;11(6):431-7.
2010: Seiji Miyauchi; Elangovan Gopal; Ellappan Babu; Sonne R Srinivas; Yoshiyuki Kubo; Umapathy Siddaramappa; Santoshanand V Thakkar; Vadivel Ganapathy; Puttur D Prasad
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
Biochimica et biophysica acta 2010;1798(6):1164-71.
2010: Sudha Ananth; Lina Zhuang; Elangovan Gopal; Shiro Itagaki; Babu Ellappan; Sylvia B Smith; Vadivel Ganapathy; Pamela Moore Martin
Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon.
Biochemical and biophysical research communications 2010;394(1):75-80.
2010: Sudharsan Periyasamy-Thandavan; William H Jackson; Julia S Samaddar; Brian Erickson; John R Barrett; Lauren Raney; Elangovan Gopal; Vadivel Ganapathy; William Hill; Kapil N Bhalla; Patricia V Schoenlein
Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.
Autophagy 2010;6(1):19-35.
2009: Muthusamy Thangaraju; Senthil K Karunakaran; Shiro Itagaki; Elangovan Gopal; Selvakumar Elangovan; Puttur D Prasad; Vadivel Ganapathy
Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate.
Cancer 2009;115(20):4655-66.
2008: Vadivel Ganapathy; Muthusamy Thangaraju; Elangovan Gopal; Pamela Moore Martin; Shirou Itagaki; Seiji Miyauchi; Puttur D Prasad
Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.
The AAPS journal 2008;10(1):193-9.
2007: Elangovan Gopal; Umapathy Siddaramappa; Pamela Moore Martin; Sudha Ananth; Jaya P Gnana-Prakasam; H Becker; Carsten A Wagner; Vadivel Ganapathy; Puttur D Prasad
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.
Biochimica et biophysica acta 2007;1768(11):2690-7.
2007: Seiji Miyauchi; Elangovan Gopal; Santosh V Thakkar; Satoshi Ichikawa; Puttur D Prasad; Vadivel Ganapathy
Differential modulation of sodium- and chloride-dependent opioid peptide transport system by small nonopioid peptides and free amino acids.
The Journal of pharmacology and experimental therapeutics 2007;321(1):257-64.
2007: Elangovan Gopal; Seiji Miyauchi; Pamela Moore Martin; Sudha Ananth; Penny Roon; Sylvia B Smith; Vadivel Ganapathy
Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract.
Pharmaceutical research 2007;24(3):575-84.
2007: Elangovan Gopal; Seiji Miyauchi; Pamela Moore Martin; Sudha Ananth; Sonne R Srinivas; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G402-8.
2006: Muthusamy Thangaraju; Elangovan Gopal; Pamela Moore Martin; Sudha Ananth; Sylvia B Smith; Puttur D Prasad; Esta Sterneck; Vadivel Ganapathy
SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.
Cancer research 2006;66(24):11560-4.
2006: Pamela Moore Martin; Elangovan Gopal; Sudha Ananth; Lina Zhuang; Shirou Itagaki; Balakrishna M Prasad; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain.
Journal of neurochemistry 2006;98(1):279-88.
2006: Shirou Itagaki; Elangovan Gopal; Lina Zhuang; You-Jun Fei; Seiji Miyauchi; Puttur D Prasad; Vadivel Ganapathy
Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8).
Pharmaceutical research 2006;23(6):1209-16.
2006: Seiji Miyauchi; Sonne R Srinivas; You-Jun Fei; Elangovan Gopal; Umapathy Siddaramappa; Heng Wang; S J Conway; Vadivel Ganapathy; Puttur D Prasad
Functional characteristics of NaS2, a placenta-specific Na+-coupled transporter for sulfate and oxyanions of the micronutrients selenium and chromium.
Placenta 2006;27(6-7):550-9.
2005: Sonne R Srinivas; Elangovan Gopal; Lina Zhuang; Shirou Itagaki; Pamela Moore Martin; You-Jun Fei; Vadivel Ganapathy; Puttur D Prasad
Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).
The Biochemical journal 2005;392(Pt 3):655-64.
2005: Elangovan Gopal; You-Jun Fei; Seiji Miyauchi; Lina Zhuang; Puttur D Prasad; Vadivel Ganapathy
Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.
The Biochemical journal 2005;388(Pt 1):309-16.
2005: Vadivel Ganapathy; Elangovan Gopal; Seiji Miyauchi; Puttur D Prasad
Biological functions of SLC5A8, a candidate tumour suppressor.
Biochemical Society transactions 2005;33(Pt 1):237-40.
2004: Elangovan Gopal; You-Jun Fei; Mitsuru Sugawara; Seiji Miyauchi; Lina Zhuang; Pamela Moore Martin; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate.
The Journal of biological chemistry 2004;279(43):44522-32.
2004: Seiji Miyauchi; Elangovan Gopal; You-Jun Fei; Vadivel Ganapathy
Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids.
The Journal of biological chemistry 2004;279(14):13293-6.
2004: Katsuhisa Inoue; You-Jun Fei; Lina Zhuang; Elangovan Gopal; Seiji Miyauchi; Vadivel Ganapathy
Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates.
The Biochemical journal 2004;378(Pt 3):949-57.