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Warren Fiskus

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Disorders

Leukemia, Myeloid, Acute

Phenomena

Procedures

Antineoplastic Combined Chemotherapy Protocols

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Publications

TOP 3
Fiskus Warren; Wang Yongchao; Sreekumar Arun; Buckley Kathleen M; Shi Huidong; Jillella Anand; Ustun Celalettin; Rao Rekha; Fernandez Pravina; Chen Jianguang; Balusu Ramesh; Koul Sanjay; Atadja Peter; Marquez Victor E; Bhalla Kapil N
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
Rao Rekha; Lee Pearl; Fiskus Warren; Yang Yonghua; Joshi Rajeshree; Wang Yongchao; Buckley Kate; Balusu Ramesh; Chen Jianguang; Koul Sanjay; Joshi Atul; Upadhyay Sunil; Tao Jianguo; Sotomayor Eduardo; Bhalla Kapil N
Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells.
Buckley Kathleen; Fiskus Warren; Bhalla Kapil
Activation of mTOR: A new mechanism "PIMed".

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All Publications

2009: Fiskus Warren; Wang Yongchao; Sreekumar Arun; Buckley Kathleen M; Shi Huidong; Jillella Anand; Ustun Celalettin; Rao Rekha; Fernandez Pravina; Chen Jianguang; Balusu Ramesh; Koul Sanjay; Atadja Peter; Marquez Victor E; Bhalla Kapil N
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
Blood 2009;114(13):2733-43.
2009: Rao Rekha; Lee Pearl; Fiskus Warren; Yang Yonghua; Joshi Rajeshree; Wang Yongchao; Buckley Kate; Balusu Ramesh; Chen Jianguang; Koul Sanjay; Joshi Atul; Upadhyay Sunil; Tao Jianguo; Sotomayor Eduardo; Bhalla Kapil N
Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells.
Cancer biology & therapy 2009;8(13):1273-80.
2009: Buckley Kathleen; Fiskus Warren; Bhalla Kapil
Activation of mTOR: A new mechanism "PIMed".
Cancer biology & therapy 2009;8(9):854-5.
2009: Fiskus Warren; Buckley Kate; Rao Rekha; Mandawat Aditya; Yang Yonghua; Joshi Rajeshree; Wang Yongchao; Balusu Ramesh; Chen Jianguang; Koul Sanjay; Joshi Atul; Upadhyay Sunil; Atadja Peter; Bhalla Kapil N
Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.
Cancer biology & therapy 2009;8(10):939-50.
2009: Ustun Celalettin; Corless Christopher L; Savage Natasha; Fiskus Warren; Manaloor Elizabeth; Heinrich Michael C; Lewis Grant; Ramalingam Preetha; Kepten Ilana; Jillella Anand; Bhalla Kapil
Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V.
Leukemia research 2009;33(5):735-41.
2009: Chen Jianguang; Fiskus Warren; Eaton Kelly; Fernandez Pravina; Wang Yongchao; Rao Rekha; Lee Pearl; Joshi Rajeshree; Yang Yonghua; Kolhe Ravindra; Balusu Ramesh; Chappa Prasanthi; Natarajan Kavita; Jillella Anand; Atadja Peter; Bhalla Kapil N
Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77-based mechanism.
Blood 2009;113(17):4038-48.
2008: Fiskus Warren; Wang Yongchao; Joshi Rajeshree; Rao Rekha; Yang Yonghua; Chen Jianguang; Kolhe Ravindra; Balusu Ramesh; Eaton Kelly; Lee Pearl; Ustun Celalettin; Jillella Anand; Buser Carolyn A; Peiper Stephen; Bhalla Kapil
Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(19):6106-15.
2008: Fiskus Warren; Rao Rekha; Fernandez Pravina; Herger Bryan; Yang Yonghua; Chen Jianguang; Kolhe Ravindra; Mandawat Aditya; Wang Yongchao; Joshi Rajeshree; Eaton Kelly; Lee Pearl; Atadja Peter; Peiper Stephen; Bhalla Kapil
Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.
Blood 2008;112(7):2896-905.
2008: Rao Rekha; Fiskus Warren; Yang Yonghua; Lee Pearl; Joshi Rajeshree; Fernandez Pravina; Mandawat Aditya; Atadja Peter; Bradner James E; Bhalla Kapil
HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
Blood 2008;112(5):1886-93.
2008: Yang Yonghua; Rao Rehka; Shen Jie; Tang Yun; Fiskus Warren; Nechtman John; Atadja Peter; Bhalla Kapil
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Cancer research 2008;68(12):4833-42.
2007: Fiskus Warren; Ren Yuan; Mohapatra Alex; Bali Purva; Mandawat Aditya; Rao Rekha; Herger Bryan; Yang Yonghua; Atadja Peter; Wu Jie; Bhalla Kapil
Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4882-90.
2006: Fiskus Warren; Pranpat Michael; Balasis Maria; Herger Bryan; Rao Rekha; Chinnaiyan Arul; Atadja Peter; Bhalla Kapil
Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.
Molecular cancer therapeutics 2006;5(12):3096-104.
2006: Fiskus Warren; Pranpat Michael; Balasis Maria; Bali Purva; Estrella Veronica; Kumaraswamy Sandhya; Rao Rekha; Rocha Kathy; Herger Bryan; Lee Francis; Richon Victoria; Bhalla Kapil
Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5869-78.
2006: Fiskus Warren; Pranpat Michael; Bali Purva; Balasis Maria; Kumaraswamy Sandhya; Boyapalle Sandhya; Rocha Kathy; Wu Jie; Giles Francis; Manley Paul W; Atadja Peter; Bhalla Kapil
Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl-expressing human leukemia cells.
Blood 2006;108(2):645-52.
2005: Guo Fei; Rocha Kathy; Bali Purva; Pranpat Michael; Fiskus Warren; Boyapalle Sandhya; Kumaraswamy Sandhya; Balasis Maria; Greedy Benjamin; Armitage E Simon M; Lawrence Nicholas; Bhalla Kapil
Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
Cancer research 2005;65(22):10536-44.
2005: Bali Purva; Pranpat Michael; Swaby Ramona; Fiskus Warren; Yamaguchi Hirohito; Balasis Maria; Rocha Kathy; Wang Hong-Gang; Richon Victoria; Bhalla Kapil
Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6382-9.
2005: Bali Purva; Pranpat Michael; Bradner James; Balasis Maria; Fiskus Warren; Guo Fei; Rocha Kathy; Kumaraswamy Sandhya; Boyapalle Sandhya; Atadja Peter; Seto Edward; Bhalla Kapil
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
The Journal of biological chemistry 2005;280(29):26729-34.
2005: George Prince; Bali Purva; Annavarapu Srinivas; Scuto Anna; Fiskus Warren; Guo Fei; Sigua Celia; Sondarva Gautam; Moscinski Lynn; Atadja Peter; Bhalla Kapil
Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
Blood 2005;105(4):1768-76.
2005: Guo Fei; Sigua Celia; Bali Purva; George Prince; Fiskus Warren; Scuto Anna; Annavarapu Srinivas; Mouttaki Abdelmoughite; Sondarva Gautam; Wei Sheng; Wu Jie; Djeu Julie; Bhalla Kapil
Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells.
Blood 2005;105(3):1246-55.
2004: Bali Purva; George Prince; Cohen Pamela; Tao Jianguo; Guo Fei; Sigua Celia; Vishvanath Anasuya; Scuto Anna; Annavarapu Srinivas; Fiskus Warren; Moscinski Lynn; Atadja Peter; Bhalla Kapil
Superior activity of the combination of histone deacetylase inhibitor LAQ824 and the FLT-3 kinase inhibitor PKC412 against human acute myelogenous leukemia cells with mutant FLT-3.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):4991-7.
2004: George Prince; Bali Purva; Cohen Pamela; Tao Jianguo; Guo Fei; Sigua Celia; Vishvanath Anasuya; Fiskus Warren; Scuto Anna; Annavarapu Srinivas; Moscinski Lynn; Bhalla Kapil
Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3.
Cancer research 2004;64(10):3645-52.
2003: Fiskus Warren; Padmalayam Indira; Kelly Tim; Guibao Christina; Baumstark Barbara R
Identification and characterization of the DdlB, FtsQ and FtsA genes upstream of FtsZ in Bartonella bacilliformis and Bartonella henselae.
DNA and cell biology 2003;22(11):743-52.
2003: Padmalayam Indira; Fiskus Warren; Massung Robert F; Baumstark Barbara R
Molecular cloning and analysis of a region of the Bartonella bacilliformis genome encoding NlpD, L-isoaspartyl methyltransferase and YajC homologs.
DNA and cell biology 2003;22(5):347-53.

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Warren Fiskus

Research Profile (preview)

Chemicals & Drugs

Anatomy

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Network (preview)

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