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DAVID PICKAR

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Disorders

Activities & Behaviors

Schizophrenic Psychology

Concepts & Ideas

Psychiatric Status Rating Scales

Chemicals & Drugs

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Anatomy

Brain

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Co-Publications
Name
65
Breier, Alan
45
Wolkowitz, Owen
21
Malhotra, Anil
18
Weinberger, Daniel
12
Su, TP
12
Elman, Igor
11
Adler, Caleb
10
Rapaport, Mark Hyman
9
Cohen, Robert
9
Hommer, Daniel
8
Kelsoe, John
7
Buchsbaum, Monte
6
nordahl, thomas
6
Semple, WE
6
Holcomb, Henry

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Publications

TOP 3
Pickar David; Vinik Jessie; Bartko John J
Pharmacotherapy of schizophrenic patients: preponderance of off-label drug use.
Zahn Theodore P; Pickar David
Autonomic activity in relation to symptom ratings and reaction time in unmedicated patients with schizophrenia.
Pickar David
Pharmacogenomics of psychiatric drug treatment.

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All Publications

2008: Pickar David; Vinik Jessie; Bartko John J
Pharmacotherapy of schizophrenic patients: preponderance of off-label drug use.
PloS one 2008;3(9):e3150.
2005: Zahn Theodore P; Pickar David
Autonomic activity in relation to symptom ratings and reaction time in unmedicated patients with schizophrenia.
Schizophrenia research 2005;79(2-3):257-70.
2003: Pickar David
Pharmacogenomics of psychiatric drug treatment.
The Psychiatric clinics of North America 2003;26(2):303-21, vii.
2003: Pickar David; Bartko John J
Effect size of symptom status in withdrawal of typical antipsychotics and subsequent clozapine treatment in patients with treatment-resistant schizophrenia.
The American journal of psychiatry 2003;160(6):1133-8.
2003: Daly R C; Su T-P; Schmidt P J; Pagliaro M; Pickar D; Rubinow D R
Neuroendocrine and behavioral effects of high-dose anabolic steroid administration in male normal volunteers.
Psychoneuroendocrinology 2003;28(3):317-31.
2003: Nicolson Rob; Brookner Frances B; Lenane Marge; Gochman Peter; Ingraham Loring J; Egan Michael F; Kendler Kenneth S; Pickar David; Weinberger Daniel R; Rapoport Judith L
Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia.
The American journal of psychiatry 2003;160(3):490-5.
2002: Elman Igor; Goldstein David S; Green Alan I; Eisenhofer Graeme; Folio Carol J; Holmes Courtney S; Pickar David; Breier Alan
Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(2):293-300.
2002: Adler Caleb M; Malhotra Anil K; Elman Igor; Pickar David; Breier Alan
Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(3):295-300.
2001: Daly R C; Su T P; Schmidt P J; Pickar D; Murphy D L; Rubinow D R
Cerebrospinal fluid and behavioral changes after methyltestosterone administration: preliminary findings.
Archives of general psychiatry 2001;58(2):172-7.
2001: Pickar D; Rubinow K
Pharmacogenomics of psychiatric disorders.
Trends in pharmacological sciences 2001;22(2):75-83.
2001: Zahn T P; Pickar D; van Kammen D P
Neuroleptic effects on autonomic activity in schizophrenia: between-group and within-subject paradigms and comparisons with controls.
Schizophrenia bulletin 2001;27(3):503-15.
2000: Raedler T J; Knable M B; Jones D W; Lafargue T; Urbina R A; Egan M F; Pickar D; Weinberger D R
In vivo olanzapine occupancy of muscarinic acetylcholine receptors in patients with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(1):56-68.
2000: Adler C M; Elman I; Weisenfeld N; Kestler L; Pickar D; Breier A
Effects of acute metabolic stress on striatal dopamine release in healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(5):545-50.
2000: Bertolino A; Breier A; Callicott J H; Adler C; Mattay V S; Shapiro M; Frank J A; Pickar D; Weinberger D R
The relationship between dorsolateral prefrontal neuronal N-acetylaspartate and evoked release of striatal dopamine in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(2):125-32.
1999: Cohen R M; Nordahl T E; Semple W E; Pickar D
The brain metabolic patterns of clozapine- and fluphenazine-treated female patients with schizophrenia: evidence of a sex effect.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(5):632-40.
1999: Adler C M; Malhotra A K; Elman I; Goldberg T; Egan M; Pickar D; Breier A
Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia.
The American journal of psychiatry 1999;156(10):1646-9.
1999: Miller F G; Pickar D; Rosenstein D L
Addressing ethical issues in the psychiatric research literature.
Archives of general psychiatry 1999;56(8):763-4.
1999: Raedler T J; Knable M B; Lafargue T; Urbina R A; Egan M F; Pickar D; Weinberger D R
In vivo determination of striatal dopamine D2 receptor occupancy in patients treated with olanzapine.
Psychiatry research 1999;90(2):81-90.
1999: Breier A; Su T P; Malhotra A K; Elman I; Adler C M; Weisenfeld N I; Pickar D
Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(4):340-5.
1999: Breier A F; Malhotra A K; Su T P; Pinals D A; Elman I; Adler C M; Lafargue R T; Clifton A; Pickar D
Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response.
The American journal of psychiatry 1999;156(2):294-8.
1999: Elman I; Goldstein D S; Eisenhofer G; Folio J; Malhotra A K; Adler C M; Pickar D; Breier A
Mechanism of peripheral noradrenergic stimulation by clozapine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(1):29-34.
1998: Aloia M S; Gourovitch M L; Missar D; Pickar D; Weinberger D R; Goldberg T E
Cognitive substrates of thought disorder, II: specifying a candidate cognitive mechanism.
The American journal of psychiatry 1998;155(12):1677-84.
1998: Goldberg T E; Aloia M S; Gourovitch M L; Missar D; Pickar D; Weinberger D R
Cognitive substrates of thought disorder, I: the semantic system.
The American journal of psychiatry 1998;155(12):1671-6.
1998: Malhotra A K; Breier A; Goldman D; Picken L; Pickar D
The apolipoprotein E epsilon 4 allele is associated with blunting of ketamine-induced psychosis in schizophrenia. A preliminary report.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;19(5):445-8.
1998: Breier A; Kestler L; Adler C; Elman I; Wiesenfeld N; Malhotra A; Pickar D
Dopamine D2 receptor density and personal detachment in healthy subjects.
The American journal of psychiatry 1998;155(10):1440-2.
1998: Malhotra A K; Goldman D; Mazzanti C; Clifton A; Breier A; Pickar D
A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics.
Molecular psychiatry 1998;3(4):328-32.
1998: Elman I; Adler C M; Malhotra A K; Bir C; Pickar D; Breier A
Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia.
The American journal of psychiatry 1998;155(7):979-81.
1998: Cohen R M; Nordahl T E; Semple W E; Andreason P; Pickar D
Abnormalities in the distributed network of sustained attention predict neuroleptic treatment response in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;19(1):36-47.
1998: Adler C M; Goldberg T E; Malhotra A K; Pickar D; Breier A
Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers.
Biological psychiatry 1998;43(11):811-6.
1998: Breier A; Adler C M; Weisenfeld N; Su T P; Elman I; Picken L; Malhotra A K; Pickar D
Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach.
Synapse (New York, N.Y.) 1998;29(2):142-7.
1998: Pickar D
The D2 receptor: love it and leave it.
Molecular psychiatry 1998;3(2):101-2.
1998: Pinals D A; Malhotra A K; Breier A; Pickar D
Informed consent in schizophrenia research.
Psychiatric services (Washington, D.C.) 1998;49(2):244.
1998: Malhotra A K; Goldman D; Buchanan R W; Rooney W; Clifton A; Kosmidis M H; Breier A; Pickar D
The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response.
Molecular psychiatry 1998;3(1):72-5.
1998: Pearsall R; Glick I D; Pickar D; Suppes T; Tauscher J; Jobson K O
A new algorithm for treating schizophrenia.
Psychopharmacology bulletin 1998;34(3):349-53.
1998: Murphy D L; Karoum F; Pickar D; Cohen R M; Lipper S; Mellow A M; Tariot P N; Sunderland T
Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline).
Journal of neural transmission. Supplementum 1998;52():39-48.
1997: Su T P; Malhotra A K; Hadd K; Breier A; Pickar D
D2 dopamine receptor occupancy: a crossover comparison of risperidone with clozapine therapy in schizophrenic patients.
Archives of general psychiatry 1997;54(10):972-3.
1997: Malhotra A K; Adler C M; Kennison S D; Elman I; Pickar D; Breier A
Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine.
Biological psychiatry 1997;42(8):664-8.
1997: Pickar D; Malhotra A K; Rooney W; Breier A; Goldman D
Apolipoprotein E epsilon 4 and clinical phenotype in schizophrenia.
Lancet 1997;350(9082):930-1.
1997: Malhotra A K; Pinals D A; Adler C M; Elman I; Clifton A; Pickar D; Breier A
Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(3):141-50.
1997: De Bartolomeis A; Koprivica V; Pickar D; Crawley J N; Abbott L C
Opioidergic and dopaminergic gene expression in the caudate-putamen and accumbens of the mutant mouse, tottering (tg/tg).
Brain research. Molecular brain research 1997;46(1-2):321-4.
1997: Breier A; Malhotra A K; Pinals D A; Weisenfeld N I; Pickar D
Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers.
The American journal of psychiatry 1997;154(6):805-11.
1997: Rapaport M H; McAllister C G; Pickar D; Tamarkin L; Kirch D G; Paul S M
CSF IL-1 and IL-2 in medicated schizophrenic patients and normal volunteers.
Schizophrenia research 1997;25(2):123-9.
1997: Cohen R M; Nordahl T E; Semple W E; Andreason P; Litman R E; Pickar D
The brain metabolic patterns of clozapine- and fluphenazine-treated patients with schizophrenia during a continuous performance task.
Archives of general psychiatry 1997;54(5):481-6.
1997: Litman R E; Torrey E F; Hommer D W; Radant A R; Pickar D; Weinberger D R
A quantitative analysis of smooth pursuit eye tracking in monozygotic twins discordant for schizophrenia.
Archives of general psychiatry 1997;54(5):417-26.
1997: Carson R E; Breier A; de Bartolomeis A; Saunders R C; Su T P; Schmall B; Der M G; Pickar D; Eckelman W C
Quantification of amphetamine-induced changes in [11C]raclopride binding with continuous infusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(4):437-47.
1997: Breier A; Su T P; Saunders R; Carson R E; Kolachana B S; de Bartolomeis A; Weinberger D R; Weisenfeld N; Malhotra A K; Eckelman W C; Pickar D
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2569-74.
1997: Jacobsen L K; Frazier J A; Malhotra A K; Karoum F; McKenna K; Gordon C T; Hamburger S D; Lenane M C; Pickar D; Potter W Z; Rapoport J L
Cerebrospinal fluid monoamine metabolites in childhood-onset schizophrenia.
The American journal of psychiatry 1997;154(1):69-74.
1996: Pinals D A; Malhotra A K; Missar C D; Pickar D; Breier A
Lack of gender differences in neuroleptic response in patients with schizophrenia.
Schizophrenia research 1996;22(3):215-22.
1996: Pickar D; Su T P; Weinberger D R; Coppola R; Malhotra A K; Knable M B; Lee K S; Gorey J; Bartko J J; Breier A; Hsiao J
Individual variation in D2 dopamine receptor occupancy in clozapine-treated patients.
The American journal of psychiatry 1996;153(12):1571-8.
1996: Malhotra A K; Goldman D; Ozaki N; Rooney W; Clifton A; Buchanan R W; Breier A; Pickar D
Clozapine response and the 5HT2C Cys23Ser polymorphism.
Neuroreport 1996;7(13):2100-2.
1996: Malhotra A K; Goldman D; Ozaki N; Breier A; Buchanan R; Pickar D
Lack of association between polymorphisms in the 5-HT2A receptor gene and the antipsychotic response to clozapine.
The American journal of psychiatry 1996;153(8):1092-4.
1996: Malhotra A K; Goldman D; Buchanan R; Breier A; Pickar D
5HT 2a receptor T102C polymorphism and schizophrenia.
Lancet 1996;347(9018):1830-1.
1996: Litman R E; Su T P; Potter W Z; Hong W W; Pickar D
Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine.
The British journal of psychiatry : the journal of mental science 1996;168(5):571-9.
1996: Malhotra A K; Pinals D A; Weingartner H; Sirocco K; Missar C D; Pickar D; Breier A
NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;14(5):301-7.
1996: Daniel D G; Goldberg T E; Weinberger D R; Kleinman J E; Pickar D; Lubick L J; Williams T S
Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study.
The American journal of psychiatry 1996;153(3):417-9.
1995: Pickar D; Hsiao J K
Clozapine treatment of schizophrenia.
JAMA : the journal of the American Medical Association 1995;274(12):981-3.
1995: Schreiber J L; Breier A; Pickar D
Expressed emotion. Trait or state?
The British journal of psychiatry : the journal of mental science 1995;166(5):647-9.
1995: Pickar D
Prospects for pharmacotherapy of schizophrenia.
Lancet 1995;345(8949):557-62.
1995: Zarate C A; Daniel D G; Kinon B J; Litman R E; Naber D; Pickar D; Sato M
Algorithms for the treatment of schizophrenia.
Psychopharmacology bulletin 1995;31(3):461-7.
1995: Chung I W; Kim Y S; Ahn J S; Lee H S; Chen G; Manji H K; Potter W Z; Pickar D
Pharmacologic profile of natural products used to treat psychotic illnesses.
Psychopharmacology bulletin 1995;31(1):139-45.
1994: Rao P A; Pickar D; Gejman P V; Ram A; Gershon E S; Gelernter J
Allelic variation in the D4 dopamine receptor (DRD4) gene does not predict response to clozapine.
Archives of general psychiatry 1994;51(11):912-7.
1994: Zahn T P; Pickar D; Haier R J
Effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia.
Schizophrenia research 1994;13(2):133-44.
1994: Pickar D; Owen R R; Litman R E; Hsiao J K; Su T P
Predictors of clozapine response in schizophrenia.
The Journal of clinical psychiatry 1994;55 Suppl B():129-32.
1994: Malow B A; Reese K B; Sato S; Bogard P J; Malhotra A K; Su T P; Pickar D
Spectrum of EEG abnormalities during clozapine treatment.
Electroencephalography and clinical neurophysiology 1994;91(3):205-11.
1994: Rapaport M H; McAllister C G; Kim Y S; Han J H; Pickar D; Nelson D L; Kirch D G; Paul S M
Increased serum soluble interleukin-2 receptors in Caucasian and Korean schizophrenic patients.
Biological psychiatry 1994;35(10):767-71.
1994: Litman R E; Hommer D W; Radant A; Clem T; Pickar D
Quantitative effects of typical and atypical neuroleptics on smooth pursuit eye tracking in schizophrenia.
Schizophrenia research 1994;12(2):107-20.
1994: Pickar D; Litman R E; Hong W W; Su T P; Weissman E M; Hsiao J K; Potter W Z
Clinical response to clozapine in patients with schizophrenia.
Archives of general psychiatry 1994;51(2):159-60.
1994: de Bartolomeis A; Austin M C; Goodwin G A; Spear L P; Pickar D; Crawley J N
Dopaminergic and peptidergic mRNA levels in juvenile rat brain after prenatal cocaine treatment.
Brain research. Molecular brain research 1994;21(3-4):321-32.
1994: Gejman P V; Ram A; Gelernter J; Friedman E; Cao Q; Pickar D; Blum K; Noble E P; Kranzler H R; O'Malley S
No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis.
JAMA : the journal of the American Medical Association 1994;271(3):204-8.
1993: Malhotra A K; Litman R E; Pickar D
Adverse effects of antipsychotic drugs.
Drug safety : an international journal of medical toxicology and drug experience 1993;9(6):429-36.
1993: Goldberg T E; Gold J M; Greenberg R; Griffin S; Schulz S C; Pickar D; Kleinman J E; Weinberger D R
Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery.
The American journal of psychiatry 1993;150(9):1355-62.
1993: Rapaport M H; Wolkowitz O; Kelsoe J R; Pato C; Konicki P E; Pickar D
Beneficial effects of nalmefene augmentation in neuroleptic-stabilized schizophrenic patients.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1993;9(2):111-5.
1993: Schreiber J L; Breier A; Pickar D
Hospital vs. community.
Hospital & community psychiatry 1993;44(8):795.
1993: Owen R R; Gutierrez-Esteinou R; Hsiao J; Hadd K; Benkelfat C; Lawlor B A; Murphy D L; Pickar D
Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia.
Archives of general psychiatry 1993;50(8):636-44.
1993: Litman R E; Hong W W; Weissman E M; Su T P; Potter W Z; Pickar D
Idazoxan, an alpha 2 antagonist, augments fluphenazine in schizophrenic patients: a pilot study.
Journal of clinical psychopharmacology 1993;13(4):264-7.
1993: Hsiao J K; Colison J; Bartko J J; Doran A R; Konicki P E; Potter W Z; Pickar D
Monoamine neurotransmitter interactions in drug-free and neuroleptic-treated schizophrenics.
Archives of general psychiatry 1993;50(8):606-14.
1993: Zahn T P; Pickar D
Autonomic effects of clozapine in schizophrenia: comparison with placebo and fluphenazine.
Biological psychiatry 1993;34(1-2):3-12.
1993: Su T P; Pagliaro M; Schmidt P J; Pickar D; Wolkowitz O; Rubinow D R
Neuropsychiatric effects of anabolic steroids in male normal volunteers.
JAMA : the journal of the American Medical Association 1993;269(21):2760-4.
1993: Berman K F; Doran A R; Pickar D; Weinberger D R
Is the mechanism of prefrontal hypofunction in depression the same as in schizophrenia? Regional cerebral blood flow during cognitive activation.
The British journal of psychiatry : the journal of mental science 1993;162():183-92.
1993: Goldberg T E; Greenberg R D; Griffin S J; Gold J M; Kleinman J E; Pickar D; Schulz S C; Weinberger D R
The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia.
The British journal of psychiatry : the journal of mental science 1993;162():43-8.
1993: Rapaport M H; Torrey E F; McAllister C G; Nelson D L; Pickar D; Paul S M
Increased serum soluble interleukin-2 receptors in schizophrenic monozygotic twins.
European archives of psychiatry and clinical neuroscience 1993;243(1):7-10.
1993: Wolkowitz O M; Coppola R; Breier A; Doran A R; Rubinow D R; Berrettini W H; Kling M A; Pickar D
Quantitative electroencephalographic correlates of steroid administration in man.
Neuropsychobiology 1993;27(4):224-30.
1993: Hsiao J K; Potter W Z; Agren H; Owen R R; Pickar D
Clinical investigation of monoamine neurotransmitter interactions.
Psychopharmacology 1993;112(1 Suppl):S76-84.
1992: Goldstein D S; Breier A; Wolkowitz O M; Pickar D; Lenders J W
Plasma levels of catecholamines and corticotrophin during acute glucopenia induced by 2-deoxy-D-glucose in normal man.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 1992;2(6):359-66.
1992: Breier A; Davis O; Buchanan R; Listwak S J; Holmes C; Pickar D; Goldstein D S
Effects of alprazolam on pituitary-adrenal and catecholaminergic responses to metabolic stress in humans.
Biological psychiatry 1992;32(10):880-90.
1992: Breier A; Schreiber J L; Dyer J; Pickar D
Course of illness and predictors of outcome in chronic schizophrenia: implications for pathophysiology.
The British journal of psychiatry. Supplement 1992;(18):38-43.
1992: Pickar D; Owen R R; Litman R E; Konicki E; Gutierrez R; Rapaport M H
Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine.
Archives of general psychiatry 1992;49(5):345-53.
1992: Pickar D
Plasma homovanillic acid and other predictors of clozapine response.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():516A-517A.
1992: Pickar D; Hsiao J K; Litman R E
Regional brain metabolism as predictors of clozapine response.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():399A-400A.
1991: Litman R E; Hommer D W; Clem T; Ornsteen M L; Ollo C; Pickar D
Correlation of Wisconsin Card Sorting Test performance with eye tracking in schizophrenia.
The American journal of psychiatry 1991;148(11):1580-2.
1991: Hommer D W; Clem T; Litman R; Pickar D
Maladaptive anticipatory saccades in schizophrenia.
Biological psychiatry 1991;30(8):779-94.
1991: Wolkowitz O M; Pickar D
Benzodiazepines in the treatment of schizophrenia: a review and reappraisal.
The American journal of psychiatry 1991;148(6):714-26.
1991: Daniel D G; Kim E; Kostianovsky D; Goldberg T E; Casanova M F; Pickar D; Kleinman J E; Weinberger D R
Computed tomography measurements of brain density in Schizophrenia.
Biological psychiatry 1991;29(8):745-56.
1991: Rapaport M H; McAllister C G; Kirch D G; Pickar D
The effects of typical and atypical neuroleptics on mitogen-induced T lymphocyte responsiveness.
Biological psychiatry 1991;29(7):715-7.
1991: Breier A; Schreiber J L; Dyer J; Pickar D
National Institute of Mental Health longitudinal study of chronic schizophrenia. Prognosis and predictors of outcome.
Archives of general psychiatry 1991;48(3):239-46.
1991: Konicki P E; Owen R R; Litman R E; Pickar D
The acute effects of central- and peripheral-acting dopamine antagonists on plasma HVA in schizophrenic patients.
Life sciences 1991;48(14):1411-6.
1990: Wolkowitz O M; Bartko J J; Pickar D
Drug trials and heterogeneity in schizophrenia: the mean is not the end.
Biological psychiatry 1990;28(12):1021-5.
1990: Breier A; Wolkowitz O M; Roy A; Potter W Z; Pickar D
Plasma norepinephrine in chronic schizophrenia.
The American journal of psychiatry 1990;147(11):1467-70.
1990: Wolkowitz O M; Reus V I; Weingartner H; Thompson K; Breier A; Doran A; Rubinow D; Pickar D
Cognitive effects of corticosteroids.
The American journal of psychiatry 1990;147(10):1297-303.
1990: Wolkowitz O M; Rubinow D; Doran A R; Breier A; Berrettini W H; Kling M A; Pickar D
Prednisone effects on neurochemistry and behavior. Preliminary findings.
Archives of general psychiatry 1990;47(10):963-8.
1990: Muscettola G; Barbato G; de Bartolomeis A; Monteleone P; Pickar D
Plasma HVA, tardive dyskinesia and psychotic symptoms in long-term drug-free inpatients with schizophrenia.
Psychiatry research 1990;33(3):259-67.
1990: Lucas P B; Pickar D; Kelsoe J; Rapaport M; Pato C; Hommer D
Effects of the acute administration of caffeine in patients with schizophrenia.
Biological psychiatry 1990;28(1):35-40.
1990: Pickar D; Breier A; Hsiao J K; Doran A R; Wolkowitz O M; Pato C N; Konicki P E; Potter W Z
Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia.
Archives of general psychiatry 1990;47(7):641-8.
1990: Doran A R; Labarca R; Wolkowitz O M; Roy A; Douillet P; Pickar D
Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia.
Archives of general psychiatry 1990;47(6):558-63.
1990: Schreiber J L; Breier A; Pickar D
Characteristics of patients selected for treatment on a schizophrenia research unit.
Hospital & community psychiatry 1990;41(4):441-3.
1990: Cottingham S L; Pickar D; Shimotake T K; Montpied P; Paul S M; Crawley J N
Tyrosine hydroxylase and cholecystokinin mRNA levels in the substantia nigra, ventral tegmental area, and locus ceruleus are unaffected by acute and chronic haloperidol administration.
Cellular and molecular neurobiology 1990;10(1):41-50.
1990: Wolkowitz O M; Papadopoulos N M; Costello R; Breier A; Doran A R; Pickar D; Rubinow D
Prednisone effects on blood-brain barrier permeability and CNS IgG synthesis in healthy humans.
Psychoneuroendocrinology 1990;15(2):155-8.
1990: Pickar D
A clinical perspective on microdialysis.
Progress in neuro-psychopharmacology & biological psychiatry 1990;14 Suppl():S59-62.
1990: Pickar D; Litman R E; Konicki P E; Wolkowitz O M; Breier A
Neurochemical and neural mechanisms of positive and negative symptoms in schizophrenia.
Modern problems of pharmacopsychiatry 1990;24():124-51.
1989: Cohen R M; Semple W E; Gross M; Nordahl T E; King A C; Pickar D; Post R M
Evidence for common alterations in cerebral glucose metabolism in major affective disorders and schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1989;2(4):241-54.
1989: McAllister C G; Rapaport M H; Pickar D; Paul S M
Effects of short-term administration of antipsychotic drugs on lymphocyte subsets in schizophrenic patients.
Archives of general psychiatry 1989;46(10):956-7.
1989: McAllister C G; Rapaport M H; Pickar D; Podruchny T A; Christison G; Alphs L D; Paul S M
Increased numbers of CD5+ B lymphocytes in schizophrenic patients.
Archives of general psychiatry 1989;46(10):890-4.
1989: Roy A; Pickar D; Gold P; Barbaccia M; Guidotti A; Costa E; Linnoila M
Diazepam-binding inhibitor and corticotropin-releasing hormone in cerebrospinal fluid.
Acta psychiatrica Scandinavica 1989;80(3):287-91.
1989: Wolkowitz O M; Doran A; Breier A; Roy A; Pickar D
Specificity of plasma HVA response to dexamethasone in psychotic depression.
Psychiatry research 1989;29(2):177-86.
1989: Wolkowitz O M; Breier A; Doran A; Lucas P; Kelsoe J; Paul S M; Pickar D
Alprazolam augmentation of neuroleptics in schizophrenia.
The American journal of psychiatry 1989;146(8):1087-8.
1989: DeLisi L E; Buchsbaum M S; Holcomb H H; Langston K C; King A C; Kessler R; Pickar D; Carpenter W T; Morihisa J M; Margolin R
Increased temporal lobe glucose use in chronic schizophrenic patients.
Biological psychiatry 1989;25(7):835-51.
1989: Heh C W; Potkin S G; Pickar D; Costa J; Herrera J; Sramek J; DeMet E
Serum homovanillic acid concentrations in carbamazepine-treated chronic schizophrenics.
Biological psychiatry 1989;25(5):639-41.
1989: Rapaport M H; McAllister C G; Pickar D; Nelson D L; Paul S M
Elevated levels of soluble interleukin 2 receptors in schizophrenia.
Archives of general psychiatry 1989;46(3):291-2.
1989: Roy A; Pickar D; De Jong J; Karoum F; Linnoila M
Suicidal behavior in depression: relationship to noradrenergic function.
Biological psychiatry 1989;25(3):341-50.
1989: Lucas P B; Gardner D L; Cowdry R W; Pickar D
Cerebral structure in borderline personality disorder.
Psychiatry research 1989;27(2):111-5.
1989: Doran A R; Rubinow D R; Wolkowitz O M; Roy A; Breier A; Pickar D
Fluphenazine treatment reduces CSF somatostatin in patients with schizophrenia: correlations with CSF HVA.
Biological psychiatry 1989;25(4):431-9.
1989: Pickar D; Bunney W E; Douillet P; Sethi B B; Sharma M; Vartanian M E; Lideman R P; Naber D; Leibl K; Yamashita I
Repeated naloxone administration in schizophrenia: a phase II World Health Organization Study.
Biological psychiatry 1989;25(4):440-8.
1989: Roy A; Wolkowitz O; Doran A; Pickar D
TRH test in schizophrenic patients and controls.
Biological psychiatry 1989;25(4):523-6.
1989: Litman R E; Hommer D W; Clem T; Rapaport M H; Pato C N; Pickar D
Smooth pursuit eye movements in schizophrenia: effects of neuroleptic treatment and caffeine.
Psychopharmacology bulletin 1989;25(3):473-8.
1989: Pato C N; Wolkowitz O M; Rapaport M; Schulz S C; Pickar D
Benzodiazepine augmentation of neuroleptic treatment in patients with schizophrenia.
Psychopharmacology bulletin 1989;25(2):263-6.
1988: Narang P K; Blumhardt C L; Doran A R; Pickar D
Steady-state cerebrospinal fluid transfer of verapamil and metabolites in patients with schizophrenia.
Clinical pharmacology and therapeutics 1988;44(5):550-7.
1988: Breier A; Kelsoe J R; Kirwin P D; Beller S A; Wolkowitz O M; Pickar D
Early parental loss and development of adult psychopathology.
Archives of general psychiatry 1988;45(11):987-93.
1988: Roy A; Pickar D; De Jong J; Karoum F; Linnoila M
Norepinephrine and its metabolites in cerebrospinal fluid, plasma, and urine. Relationship to hypothalamic-pituitary-adrenal axis function in depression.
Archives of general psychiatry 1988;45(9):849-57.
1988: Breier A; Wolkowitz O M; Doran A R; Bellar S; Pickar D
Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers.
Psychiatry research 1988;25(2):187-94.
1988: Wolkowitz O M; Doran A R; Cohen M R; Cohen R M; Wise T N; Pickar D
Single-dose naloxone acutely reduces eating in obese humans: behavioral and biochemical effects.
Biological psychiatry 1988;24(4):483-7.
1988: Wolkowitz O M; Breier A; Doran A; Kelsoe J; Lucas P; Paul S M; Pickar D
Alprazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic patients. Preliminary results.
Archives of general psychiatry 1988;45(7):664-71.
1988: Kelsoe J R; Cadet J L; Pickar D; Weinberger D R
Quantitative neuroanatomy in schizophrenia. A controlled magnetic resonance imaging study.
Archives of general psychiatry 1988;45(6):533-41.
1988: Labarca R; Thomas J W; Koulu M; Kim Y S; Janowsky A; Wilkinson L; Linnoila M; Paul S M; Pickar D
A central 6-hydroxydopamine lesion prevents fluphenazine-induced increase in plasma homovanillic acid.
Brain research bulletin 1988;20(5):567-71.
1988: Roy A; Linnoila M; Karoum F; Pickar D
Urinary-free cortisol in depressed patients and controls: relationship to urinary indices of noradrenergic function.
Psychological medicine 1988;18(1):93-8.
1988: Roy A; Guthrie S; Karoum F; Pickar D; Linnoila M
High intercorrelations among urinary outputs of norepinephrine and its major metabolites. A replication in depressed patients and controls.
Archives of general psychiatry 1988;45(2):158-61.
1988: Shelton R C; Karson C N; Doran A R; Pickar D; Bigelow L B; Weinberger D R
Cerebral structural pathology in schizophrenia: evidence for a selective prefrontal cortical defect.
The American journal of psychiatry 1988;145(2):154-63.
1988: Roy A; Karoum F; Linnoila M; Pickar D
Thyrotropin releasing hormone test in unipolar depressed patients and controls: relationship to clinical and biologic variables.
Acta psychiatrica Scandinavica 1988;77(2):151-9.
1988: Wolkowitz O M; Breier A; Doran A; Rubinow D; Berrettini W; Coppola R; Gold P; Pickar D
Prednisone-induced behavioral and biological changes in medically healthy volunteers.
Psychopharmacology bulletin 1988;24(3):492-4.
1988: Roy A; Pickar D
TRH-induced prolactin release in unipolar depressed patients and controls.
Journal of psychiatric research 1988;22(3):221-5.
1988: Friedhoff A J; Pickar D; Axelrod J; Creese I; Davis K L; Gallagher D W; Greengard P; Housman D; Maas J W; Richelson E
Neurochemistry and neuropharmacology.
Schizophrenia bulletin 1988;14(3):399-412.
1988: Pickar D; Breier A; Kelsoe J
Plasma homovanillic acid as an index of central dopaminergic activity: studies in schizophrenic patients.
Annals of the New York Academy of Sciences 1988;537():339-46.
1988: Pickar D
Perspectives on a time-dependent model of neuroleptic action.
Schizophrenia bulletin 1988;14(2):255-68.
1988: Cohen R M; Semple W E; Gross M; Nordahl T E; Holcomb H H; Dowling M S; Pickar D
The effect of neuroleptics on dysfunction in a prefrontal substrate of sustained attention in schizophrenia.
Life sciences 1988;43(14):1141-50.
1988: Breier A; Wolkowitz O M; Rapaport M; Paul S M; Pickar D
Metabolic stress effects in normal volunteers and schizophrenic patients.
Psychopharmacology bulletin 1988;24(3):431-3.
1987: Breier A; Wolkowitz O M; Doran A R; Roy A; Boronow J; Hommer D W; Pickar D
Neuroleptic responsivity of negative and positive symptoms in schizophrenia.
The American journal of psychiatry 1987;144(12):1549-55.
1987: Doran A R; Boronow J; Weinberger D R; Wolkowitz O M; Breier A; Pickar D
Structural brain pathology in schizophrenia revisited. Prefrontal cortex pathology is inversely correlated with cerebrospinal fluid levels of homovanillic acid.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1987;1(1):25-32.
1987: Berrettini W H; Doran A R; Kelsoe J; Roy A; Pickar D
Cerebrospinal fluid neuropeptide Y in depression and schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1987;1(1):81-3.
1987: Breier A; Arora P K; Wolkowitz O M; Pickar D; Paul S M
Metabolic stress produces rapid immunosuppression in humans.
Archives of general psychiatry 1987;44(12):1108-9.
1987: Breier A; Albus M; Pickar D; Zahn T P; Wolkowitz O M; Paul S M
Controllable and uncontrollable stress in humans: alterations in mood and neuroendocrine and psychophysiological function.
The American journal of psychiatry 1987;144(11):1419-25.
1987: Raz S; Raz N; Weinberger D R; Boronow J; Pickar D; Bigler E D; Turkheimer E
Morphological brain abnormalities in schizophrenia determined by computed tomography: a problem of measurement?
Psychiatry research 1987;22(2):91-8.
1987: Wolkowitz O M; Rubinow D R; Breier A; Doran A R; Davis C; Pickar D
Prednisone decreases CSF somatostatin in healthy humans: implications for neuropsychiatric illness.
Life sciences 1987;41(16):1929-33.
1987: Wolkowitz O M; Doran A R; Breier A; Roy A; Jimerson D C; Sutton M E; Golden R N; Paul S M; Pickar D
The effects of dexamethasone on plasma homovanillic acid and 3-methoxy-4-hydroxyphenylglycol. Evidence for abnormal corticosteroid-catecholamine interactions in major depression.
Archives of general psychiatry 1987;44(9):782-9.
1987: Potter W Z; Rudorfer M V; Pickar D; Linnoila M
Effects of psychotropic drugs on neurotransmitters in man.
Life sciences 1987;41(7):817-20.
1987: Roy A; Guthrie S; Pickar D; Linnoila M
Plasma norepinephrine responses to cold challenge in depressed patients and normal controls.
Psychiatry research 1987;21(2):161-8.
1987: Roy A; Pickar D; Paul S; Doran A; Chrousos G P; Gold P W
CSF corticotropin-releasing hormone in depressed patients and normal control subjects.
The American journal of psychiatry 1987;144(5):641-5.
1987: Cohen R M; Semple W E; Gross M; Nordahl T E; DeLisi L E; Holcomb H H; King A C; Morihisa J M; Pickar D
Dysfunction in a prefrontal substrate of sustained attention in schizophrenia.
Life sciences 1987;40(20):2031-9.
1987: Roy A; Everett D; Pickar D; Paul S M
Platelet tritiated imipramine binding and serotonin uptake in depressed patients and controls. Relationship to plasma cortisol levels before and after dexamethasone administration.
Archives of general psychiatry 1987;44(4):320-7.
1987: Roy A; Pickar D; Linnoila M; Chrousos G P; Gold P W
Cerebrospinal fluid corticotropin-releasing hormone in depression: relationship to noradrenergic function.
Psychiatry research 1987;20(3):229-37.
1987: Pickar D; Wolkowitz O M; Doran A R; Labarca R; Roy A; Breier A; Narang P K
Clinical and biochemical effects of verapamil administration to schizophrenic patients.
Archives of general psychiatry 1987;44(2):113-8.
1987: Wolkowitz O M; Weingartner H; Thompson K; Pickar D; Paul S M; Hommer D W
Diazepam-induced amnesia: a neuropharmacological model of an "organic amnestic syndrome".
The American journal of psychiatry 1987;144(1):25-9.
1987: Pickar D; Wolkowitz O M; Labarca R; Doran A R; Breier A; Paul S M
Biochemical alterations produced by neuroleptics in man: studies of plasma homovanillic acid in schizophrenic patients.
Psychopharmacology series 1987;3():248-54.
1986: Roy A; Linnoila M; Jimerson D C; Gold P; Pickar D
Pre-menopausal and post-menopausal depressed women.
The Australian and New Zealand journal of psychiatry 1986;20(4):464-9.
1986: Amsterdam J D; Henle W; Winokur A; Wolkowitz O M; Pickar D; Paul S M
Serum antibodies to Epstein-Barr virus in patients with major depressive disorder.
The American journal of psychiatry 1986;143(12):1593-6.
1986: Barbaccia M L; Costa E; Ferrero P; Guidotti A; Roy A; Sunderland T; Pickar D; Paul S M; Goodwin F K
Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer's disease.
Archives of general psychiatry 1986;43(12):1143-7.
1986: Roy A; Agren H; Pickar D; Linnoila M; Doran A R; Cutler N R; Paul S M
Reduced CSF concentrations of homovanillic acid and homovanillic acid to 5-hydroxyindoleacetic acid ratios in depressed patients: relationship to suicidal behavior and dexamethasone nonsuppression.
The American journal of psychiatry 1986;143(12):1539-45.
1986: Roy A; Schreiber J; Mazonson A; Pickar D
Suicidal behavior in chronic schizophrenic patients: a follow-up study.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 1986;31(8):737-40.
1986: Roy A; Pickar D; Doran A; Wolkowitz O; Gallucci W; Chrousos G; Gold P
The corticotropin-releasing hormone stimulation test in chronic schizophrenia.
The American journal of psychiatry 1986;143(11):1393-7.
1986: Roy A; Pickar D; Douillet P; Karoum F; Linnoila M
Urinary monoamines and monoamine metabolites in subtypes of unipolar depressive disorder and normal controls.
Psychological medicine 1986;16(3):541-6.
1986: Pickar D; Labarca R; Doran A R; Wolkowitz O M; Roy A; Breier A; Linnoila M; Paul S M
Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.
Archives of general psychiatry 1986;43(7):669-76.
1986: Roy A; Jimerson D C; Pickar D
Plasma MHPG in depressive disorders and relationship to the dexamethasone suppression test.
The American journal of psychiatry 1986;143(7):846-51.
1986: Roy A; Linnoila M; Karoum F; Pickar D
Relative activity of metabolic pathways for norepinephrine in endogenous depression.
Acta psychiatrica Scandinavica 1986;73(6):624-8.
1986: Gold P W; Loriaux D L; Roy A; Kling M A; Calabrese J R; Kellner C H; Nieman L K; Post R M; Pickar D; Gallucci W
Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications.
The New England journal of medicine 1986;314(21):1329-35.
1986: Wolkowitz O; Sutton M; Koulu M; Labarca R; Wilkinson L; Doran A; Hauger R; Pickar D; Crawley J
Chronic corticosterone administration in rats: behavioral and biochemical evidence of increased central dopaminergic activity.
European journal of pharmacology 1986;122(3):329-38.
1986: Wolkowitz O M; Doran A R; Breier A; Cohen M R; Pickar D
Endogenous opioid regulation of hypothalamo-pituitary-adrenal axis activity in schizophrenia.
Biological psychiatry 1986;21(4):366-73.
1986: Doran A R; Rubinow D R; Roy A; Pickar D
CSF somatostatin and abnormal response to dexamethasone administration in schizophrenic and depressed patients.
Archives of general psychiatry 1986;43(4):365-9.
1986: Roy A; Pickar D; Linnoila M; Doran A R; Paul S M
Cerebrospinal fluid monoamine and monoamine metabolite levels and the dexamethasone suppression test in depression. Relationship to life events.
Archives of general psychiatry 1986;43(4):356-60.
1986: Roy A; Gold P; Pickar D; Wolkowitz O M; Chrousos G; Paul S M
Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls.
Journal of affective disorders 1986;10(2):95-9.
1986: Pickar D
Neuroleptics, dopamine, and schizophrenia.
The Psychiatric clinics of North America 1986;9(1):35-48.
1986: Roy A; Linnoila M; Karoum F; Pickar D
Urinary excretion of free tyramine and of norepinephrine and its metabolites in unipolar depressed patients.
Biological psychiatry 1986;21(2):221-4.
1986: Wolkowitz O M; Pickar D; Doran A R; Breier A; Tarell J; Paul S M
Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia.
The American journal of psychiatry 1986;143(1):85-7.
1986: Buchsbaum M S; Awsare S V; Holcomb H H; DeLisi L E; Hazlett E; Carpenter W T; Pickar D; Morihisa J M
Topographic differences between normals and schizophrenics: the N120 evoked potential component.
Neuropsychobiology 1986;15(1):1-6.
1986: Pickar D; Roy A; Breier A; Doran A; Wolkowitz O; Colison J; Agren H
Suicide and aggression in schizophrenia. Neurobiologic correlates.
Annals of the New York Academy of Sciences 1986;487():189-96.
1985: Campbell I C; Durcan M J; Cohen R M; Pickar D; Chugani D; Murphy D L
Chronic clorgyline and pargyline increase apomorphine-induced stereotypy in the rat.
Pharmacology, biochemistry, and behavior 1985;23(6):921-5.
1985: Roy A; Pickar D; Linnoila M; Potter W Z
Plasma norepinephrine level in affective disorders. Relationship to melancholia.
Archives of general psychiatry 1985;42(12):1181-5.
1985: Roy A; Pickar D
Lithium potentiation of imipramine in treatment resistant depression.
The British journal of psychiatry : the journal of mental science 1985;147():582-3.
1985: Wolkowitz O M; Sutton M E; Doran A R; Labarca R; Roy A; Thomas J W; Pickar D; Paul S M
Dexamethasone increases plasma HVA but not MHPG in normal humans.
Psychiatry research 1985;16(2):101-9.
1985: Roy A; Breier A; Doran A R; Pickar D
Life events in depression. Relationship to subtypes.
Journal of affective disorders 1985;9(2):143-8.
1985: Wolkowitz O M; Doran A R; Cohen M R; Cohen R M; Wise T N; Pickar D
Effect of naloxone on food consumption in obesity.
The New England journal of medicine 1985;313(5):327.
1985: Roy A; Pickar D; Linnoila M; Doran A R; Ninan P; Paul S M
Cerebrospinal fluid monoamine and monoamine metabolite concentrations in melancholia.
Psychiatry research 1985;15(4):281-92.
1985: Cohen M R; Cohen R M; Pickar D; Kreger D; McLellan C; Murphy D L
Hormonal effects of high dose naloxone in humans.
Neuropeptides 1985;6(4):373-80.
1985: DeLisi L E; Holcomb H H; Cohen R M; Pickar D; Carpenter W; Morihisa J M; King A C; Kessler R; Buchsbaum M S
Positron emission tomography in schizophrenic patients with and without neuroleptic medication.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1985;5(2):201-6.
1985: Crawley J N; Sutton M E; Pickar D
Animal models of self-destructive behavior and suicide.
The Psychiatric clinics of North America 1985;8(2):299-310.
1985: Doran A R; Narang P K; Meigs C Y; Wolkowitz O M; Roy A; Breier A; Pickar D
Verapamil concentrations in cerebrospinal fluid after oral administration.
The New England journal of medicine 1985;312(19):1261-2.
1985: Cohen M R; Pickar D; Cohen R M
High-dose naloxone administration in chronic schizophrenia.
Biological psychiatry 1985;20(5):573-5.
1985: Roy A; Ninan P; Mazonson A; Pickar D; Van Kammen D; Linnoila M; Paul S M
CSF monoamine metabolites in chronic schizophrenic patients who attempt suicide.
Psychological medicine 1985;15(2):335-40.
1985: Cohen M R; Cohen R M; Pickar D; Murphy D L
Naloxone reduces food intake in humans.
Psychosomatic medicine 1985;47(2):132-8.
1985: Boronow J; Pickar D; Ninan P T; Roy A; Hommer D; Linnoila M; Paul S M
Atrophy limited to the third ventricle in chronic schizophrenic patients. Report of a controlled series.
Archives of general psychiatry 1985;42(3):266-71.
1985: Crawley J N; Ninan P T; Pickar D; Chrousos G P; Linnoila M; Skolnick P; Paul S M
Neuropharmacological antagonism of the beta-carboline-induced "anxiety" response in rhesus monkeys.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(2):477-85.
1985: Roy A; Pickar D; Ninan P; Hooks J; Paul S M
A search for interferon in the CSF of chronic schizophrenic patients.
The American journal of psychiatry 1985;142(2):269.
1985: Roy A; Sutton M; Pickar D
Neuroendocrine and personality variables in dysthymic disorder.
The American journal of psychiatry 1985;142(1):94-7.
1985: DeLisi L E; Buchsbaum M S; Holcomb H H; Dowling-Zimmerman S; Pickar D; Boronow J; Morihisa J M; van Kammen D P; Carpenter W; Kessler R
Clinical correlates of decreased anteroposterior metabolic gradients in positron emission tomography (PET) of schizophrenic patients.
The American journal of psychiatry 1985;142(1):78-81.
1985: Cowdry R W; Pickar D; Davies R
Symptoms and EEG findings in the borderline syndrome.
International journal of psychiatry in medicine 1985;15(3):201-11.
1985: Doran A R; Pickar D; Labarca R; Douillet P; Wolkowitz O M; Thomas J W; Roy A; Paul S M
Evidence for a daily rhythm of plasma HVA in normal controls but not in schizophrenic patients.
Psychopharmacology bulletin 1985;21(3):694-7.
1985: Sunderland T; Mueller E A; Cohen R M; Jimerson D C; Pickar D; Murphy D L
Tyramine pressor sensitivity changes during deprenyl treatment.
Psychopharmacology 1985;86(4):432-7.
1985: Hommer D W; Pickar D; Crawley J N; Weingartner H; Paul S M
The effects of cholecystokinin-like peptides in schizophrenics and normal human subjects.
Annals of the New York Academy of Sciences 1985;448():542-52.
1984: Cohen M R; Pickar D; Cohen R M; Wise T N; Cooper J N
Plasma cortisol and beta-endorphin immunoreactivity in human obesity.
Psychosomatic medicine 1984;46(5):454-62.
1984: Pickar D; Labarca R; Linnoila M; Roy A; Hommer D; Everett D; Paul S M
Neuroleptic-induced decrease in plasma homovanillic acid and antipsychotic activity in schizophrenic patients.
Science (New York, N.Y.) 1984;225(4665):954-7.
1984: Bullinger M; Naber D; Pickar D; Cohen R M; Kalin N H; Pert A; Bunney W E
Endocrine effects of the cold pressor test: relationships to subjective pain appraisal and coping.
Psychiatry research 1984;12(3):227-33.
1984: Naber D; Pickar D
[Endorphins and endogenous psychoses]
Der Nervenarzt 1984;55(7):378-81.
1984: Cohen M R; Cohen R M; Pickar D; Sunderland T; Mueller E A; Murphy D L
High dose naloxone in depression.
Biological psychiatry 1984;19(6):825-32.
1984: Hommer D W; Pickar D; Roy A; Ninan P; Boronow J; Paul S M
The effects of ceruletide in schizophrenia.
Archives of general psychiatry 1984;41(6):617-9.
1984: Roy A; Pickar D; Paul S
Biologic tests in depression.
Psychosomatics 1984;25(6):443-7, 451.
1984: Cohen M R; Pickar D; Extein I; Gold M S; Sweeney D R
Plasma cortisol and beta-endorphin immunoreactivity in nonmajor and major depression.
The American journal of psychiatry 1984;141(5):628-32.
1984: Muscettola G; Potter W Z; Pickar D; Goodwin F K
Urinary 3-methoxy-4-hydroxyphenylglycol and major affective disorders. A replication and new findings.
Archives of general psychiatry 1984;41(4):337-42.
1984: Roy A; Mazonson A; Pickar D
Attempted suicide in chronic schizophrenia.
The British journal of psychiatry : the journal of mental science 1984;144():303-6.
1984: Hommer D W; Zahn T P; Pickar D; van Kammen D P
Prazosin, a specific alpha 1-noradrenergic receptor antagonist, has no effect on symptoms but increases autonomic arousal in schizophrenic patients.
Psychiatry research 1984;11(3):193-204.
1984: Pickar D; Dubois M; Cohen M R
Behavioral change in a cancer patient following intrathecal beta-endorphin administration.
The American journal of psychiatry 1984;141(1):103-4.
1984: Crawley J N; Ninan P T; Pickar D; Chrousos G P; Skolnick P; Paul S M
Behavioral and physiological responses to benzodiazepine receptor antagonists.
Psychopharmacology bulletin 1984;20(3):403-7.
1983: Risch S C; Kalin N H; Janowsky D S; Cohen R M; Pickar D; Murphy D L
Co-release of ACTH and beta-endorphin immunoreactivity in human subjects in response to central cholinergic stimulation.
Science (New York, N.Y.) 1983;222(4619):77.
1983: Insel T R; Pickar D
Naloxone administration in obsessive-compulsive disorder: report of two cases.
The American journal of psychiatry 1983;140(9):1219-20.
1983: Cohen M R; Pickar D; Dubois M
The role of the endogenous opioid system in the human stress response.
The Psychiatric clinics of North America 1983;6(3):457-71.
1983: Naber D; Pickar D
The measurement of endorphins in body fluids.
The Psychiatric clinics of North America 1983;6(3):443-56.
1983: Pickar D; Cohen M R; Dubois M
The relationship of plasma cortisol and beta-endorphin immunoreactivity to surgical stress and postoperative analgesic requirement.
General hospital psychiatry 1983;5(2):93-8.
1983: Cohen M R; Cohen R M; Pickar D; Weingartner H; Murphy D L
High-dose naloxone infusions in normals. Dose-dependent behavioral, hormonal, and physiological responses.
Archives of general psychiatry 1983;40(6):613-9.
1983: Pickar D
Naloxone in schizophrenia.
Lancet 1983;1(8328):819.
1983: Cohen R M; Cohen M R; Weingartner H; Pickar D; Murphy D L
High-dose naloxone affects task performance in normal subjects.
Psychiatry research 1983;8(2):127-36.
1983: Siever L J; Pickar D; Lake C R; Cohen R M; Uhde T W; Murphy D L
Extreme elevations in plasma norepinephrine associated with decreased alpha-adrenergic responsiveness in major depressive disorder: two case reports.
Journal of clinical psychopharmacology 1983;3(1):39-41.
1983: Buchsbaum M S; Davis G C; Naber D; Pickar D
Pain enhances naloxone-induced hyperalgesia in humans as assessed by somatosensory evoked potentials.
Psychopharmacology 1983;79(2-3):99-103.
1982: Dubois M; Pickar D; Cohen M; Gadde P; Macnamara T E; Bunney W E
Effects of fentanyl on the response of plasma beta-endorphin immunoreactivity to surgery.
Anesthesiology 1982;57(6):468-72.
1982: Pickar D; Cohen M R; Naber D; Cohen R M
Clinical studies of the endogenous opioid system.
Biological psychiatry 1982;17(11):1243-76.
1982: Schulz S C; van Kammen D P; Pickar D; Cohen M R; Naber D
Response of plasma beta-endorphin immunoreactivity to d-amphetamine and placebo in schizophrenic patients.
Psychiatry research 1982;7(2):171-8.
1982: Lake C R; Pickar D; Ziegler M G; Lipper S; Slater S; Murphy D L
High plasma norepinephrine levels in patients with major affective disorder.
The American journal of psychiatry 1982;139(10):1315-8.
1982: Cohen M R; Cohen R M; Pickar D; Murphy D L; Bunney W E
Physiological effects of high dose naloxone administration to normal adults.
Life sciences 1982;30(23):2025-31.
1982: Cohen R M; Weingartner H; Smallberg S A; Pickar D; Murphy D L
Effort and cognition in depression.
Archives of general psychiatry 1982;39(5):593-7.
1982: Pickar D; Murphy D L; Cohen R M; Campbell I C; Lipper S
Selective and nonselective monoamine oxidase inhibitors: behavioral disturbances during their administration to depressed patients.
Archives of general psychiatry 1982;39(5):535-40.
1982: Kaye W H; Pickar D; Naber D; Ebert M H
Cerebrospinal fluid opioid activity in anorexia nervosa.
The American journal of psychiatry 1982;139(5):643-5.
1982: Cohen R M; Campbell I C; Yamaguchi I; Pickar D; Kopin I J; Murphy D L
Cardiovascular changes in response to selective monoamine oxidase inhibition in the rat.
European journal of pharmacology 1982;80(1):155-60.
1982: Pickar D; Vartanian F; Bunney W E; Maier H P; Gastpar M T; Prakash R; Sethi B B; Lideman R; Belyaev B S; Tsutsulkovskaja M V; Jungkunz G; Nedopil N; Verhoeven W; van Praag H
Short-term naloxone administration in schizophrenic and manic patients. A World Health Organization Collaborative Study.
Archives of general psychiatry 1982;39(3):313-9.
1982: Cohen M R; Pickar D; Dubois M; Bunney W E
Stress-induced plasma beta-endorphin immunoreactivity may predict postoperative morphine usage.
Psychiatry research 1982;6(1):7-12.
1982: Davis G C; Buchsbaum M S; Naber D; Pickar D; Post R; van Kammen D; Bunney W E
Altered pain perception and cerebrospinal endorphins in psychiatric illness.
Annals of the New York Academy of Sciences 1982;398():366-73.
1982: Cohen R M; Pickar D; Garnett D; Lipper S; Gillin J C; Murphy D L
REM sleep suppression induced by selective monoamine oxidase inhibitors.
Psychopharmacology 1982;78(2):137-40.
1982: Cohen M R; Pickar D; Dubois M; Nurnberger J; Roth Y; Cohen R M; Gershon E; Bunney W E
Clinical and experimental studies of stress and the endogenous opioid system.
Annals of the New York Academy of Sciences 1982;398():424-32.
1982: Pickar D; Naber D; Post R M; van Kammen D P; Kaye W; Rubinow D R; Ballenger J C; Bunney W E
Endorphins in the cerebrospinal fluid of psychiatric patients.
Annals of the New York Academy of Sciences 1982;398():399-412.
1981: Naber D; Pickar D; Post R M; Van Kammen D P; Waters R N; Ballenger J C; Goodwin F K; Bunney W E
Endogenous opioid activity and beta-endorphin immunoreactivity in CSF of psychiatric patients and normal volunteers.
The American journal of psychiatry 1981;138(11):1457-62.
1981: Cohen M R; Cohen R M; Pickar D; Weingartner H; Murphy D L; Bunney W E
Behavioural effects after high dose naloxone administration to normal volunteers.
Lancet 1981;2(8255):1110.
1981: Dubois M; Pickar D; Cohen M R; Roth Y F; Macnamara T; Bunney W E
Surgical stress in humans is accompanied by an increase in plasma beta-endorphin immunoreactivity.
Life sciences 1981;29(12):1249-54.
1981: Cohen M R; Nurnberger J I; Pickar D; Gershon E; Bunney W E
Dextroamphetamine infusions in normals result in correlated increases of plasma beta-endorphin and cortisol immunoreactivity.
Life sciences 1981;29(12):1243-7.
1981: Naber D; Soble M G; Pickar D
Ethanol increases opioid activity in plasma of normal volunteers.
Pharmacopsychiatria 1981;14(5):160-1.
1981: Rubinow D R; Post R M; Pickar D; Naber D; Ballenger J C; Gold P W; Bunney W E
Relationship between urinary free cortisol and CSF opioid binding activity in depressed patients and normal volunteers.
Psychiatry research 1981;5(1):87-93.
1981: Post R M; Pickar D; Naber D; Ballenger J C; Uhde T W; Bunney W E
Effect of carbamazepine on CSF opioid activity; relationship to antidepressant response.
Psychiatry research 1981;5(1):59-66.
1981: Cohen M R; Pickar D
Pharmacological challenges to the endogenous opioid system in affective illness.
Journal of clinical psychopharmacology 1981;1(4):223-31.
1981: Naber D; Cohen R M; Pickar D; Kalin N H; Davis G; Pert C B; Bunney W E
Episodic secretion of opioid activity in human plasma and monkey CSF: evidence for a diurnal rhythm.
Life sciences 1981;28(8):931-5.
1981: Pickar D; Davis G C; Schulz S C; Extein I; Wagner R; Naber D; Gold P W; van Kammen D P; Goodwin F K; Wyatt R J; Li C H; Bunney W E
Behavioral and biological effects of acute beta-endorphin injection in schizophrenic and depressed patients.
The American journal of psychiatry 1981;138(2):160-6.
1981: Extein I; Pickar D; Gold M S; Gold P W; Pottash A L; Sweeney D R; Ross R J; Rebard R; Martin D; Goodwin F K
Methadone and morphine in depression [proceedings]
Psychopharmacology bulletin 1981;17(1):29-33.
1981: Pickar D; Naber D; Post R M; van Kammen D P; Ballenger J; Kalin N; Bunney W E
Measurement of endorphins in CSF. Relationship to psychiatric diagnosis.
Modern problems of pharmacopsychiatry 1981;17():246-62.
1981: Pickar D; Cohen R M; Jimerson D C; Lake C R; Murphy D L
Tyramine infusions and selective monoamine oxidase inhibitor treatment. II. Interrelationships among pressor sensitivity changes, platelet MAO inhibition, and plasma MHPG reduction.
Psychopharmacology 1981;74(1):8-12.
1981: Pickar D; Cohen R M; Jimerson D C; Murphy D L
Tyramine infusions and selective monoamine oxidase inhibitor treatment. I. Changes in pressor sensitivity.
Psychopharmacology 1981;74(1):4-7.
1981: Naber D; Pickar D; Davis G C; Cohen R M; Jimerson D C; Elchisak M A; Defraites E G; Kalin N H; Risch S C; Buchsbaum M S
Naloxone effects on beta-endorphin, cortisol, prolactin, growth hormone, HVA and MHPG in plasma of normal volunteers.
Psychopharmacology 1981;74(2):125-8.
1980: Cohen R M; Campbell I C; Cohen M R; Torda T; Pickar D; Siever L J; Murphy D L
Presynaptic noradrenergic regulation during depression and antidepressant drug treatment.
Psychiatry research 1980;3(1):93-105.
1980: Gold P W; Extein I; Pickar D; Rebar R; Ross R; Goodwin F K
Supression of plasma cortisol in depressed patients by acute intravenous methadone infusion.
The American journal of psychiatry 1980;137(7):862-3.
1980: Pickar D; Cutler N R; Naber D; Post R M; Pert C B; Bunney W E
Plasma opioid activity in manic-depressive illness.
Lancet 1980;1(8174):937.
1980: Cohen R M; Pickar D; Murphy D L
Myoclonus-associated hypomania during MAO-inhibitor treatment.
The American journal of psychiatry 1980;137(1):105-6.
1980: Pickar D; Lake C R; Cohen R M; Jimerson D C; Murphy D L
Alterations in noradrenergic function during clorgyline treatment.
Communications in psychopharmacology 1980;4(5):379-86.
1980: Naber D; Pickar D; Dionne R A; Bowie D L; Ewels B A; Moody T W; Soble M G; Pert C B
Assay of endogenous opiate receptor ligands in human CSF and plasma.
Substance and alcohol actions/misuse 1980;1(1):83-91.
1979: Pickar D; Cohen R M; Murphy D L; Fried D
Tyramine infusions in bipolar illness: behavioral effects and longitudinal changes in pressor sensitivity.
The American journal of psychiatry 1979;136(11):1460-3.
1979: Sturges J S; Sweeney D R; Pickar D
A follow-up neurobiological study: why volunteer?
Journal of medical ethics 1979;5(1):9-12.
1978: Cohen R; Pickar D
Implications of monoamine oxidase inhibitor-induced hypomania.
Archives of general psychiatry 1978;35(11):1393-4.
1978: Pickar D; Sweeney D R; Maas J W; Heninger G R
Primary affective disorder, clinical state change, and MHPG excretion: a longitudinal study.
Archives of general psychiatry 1978;35(11):1378-83.
1978: Sweeney D; Pickar D; Redmond D E; Maas J
Noradrenergic and dopaminergic mechanisms in Gilles de la Tourette syndrome.
Lancet 1978;1(8069):872.
1978: Pickar D; Davies R K
Tardive dyskinesia in younger patients.
The American journal of psychiatry 1978;135(3):385-6.
1975: Kupfer D J; Pickar D; Himmelhoch J M; Detre T P
Are there two types of unipolar depression?
Archives of general psychiatry 1975;32(7):866-71.

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