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J. SAMUEL ZIGLER

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Debasish Sinha; Walter J Stark; Mallika Valapala; Imran A Bhutto; Marisol Cano; Stacey Hose; Gerard A Lutty; Bonnie Patek; Fang Yang; Cheng Zhang; J. SAMUEL ZIGLER; Eric F Wawrousek
βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina.
Cheng Zhang; Laura Asnaghi; Celine Gongora; Bonnie Patek; Stacey Hose; Bo Ma; Masoud Aghsaei Fard; Lawrence Brako; Kamaljeet Singh; Morton F Goldberg; James T Handa; Woo-Kuen Lo; Charles G Eberhart; J. SAMUEL ZIGLER; Debasish Sinha
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye.
J. SAMUEL ZIGLER; Cheng Zhang; Rhonda Grebe; Gitanjali Sehrawat; Laszlo Hackler; Souvonik Adhya; Stacey Hose; D Scott McLeod; Imran A Bhutto; Walid Khaled Barbour; Geetha Parthasarathy; Donald J Zack; Yuri V Sergeev; Gerard A Lutty; James T Handa; Debasish Sinha
Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

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2012: Debasish Sinha; Walter J Stark; Mallika Valapala; Imran A Bhutto; Marisol Cano; Stacey Hose; Gerard A Lutty; Bonnie Patek; Fang Yang; Cheng Zhang; J. SAMUEL ZIGLER; Eric F Wawrousek
βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina.
Transgenic research 2012;21(5):1033-42.
2011: Cheng Zhang; Laura Asnaghi; Celine Gongora; Bonnie Patek; Stacey Hose; Bo Ma; Masoud Aghsaei Fard; Lawrence Brako; Kamaljeet Singh; Morton F Goldberg; James T Handa; Woo-Kuen Lo; Charles G Eberhart; J. SAMUEL ZIGLER; Debasish Sinha
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye.
European journal of cell biology 2011;90(5):440-8.
2011: J. SAMUEL ZIGLER; Cheng Zhang; Rhonda Grebe; Gitanjali Sehrawat; Laszlo Hackler; Souvonik Adhya; Stacey Hose; D Scott McLeod; Imran A Bhutto; Walid Khaled Barbour; Geetha Parthasarathy; Donald J Zack; Yuri V Sergeev; Gerard A Lutty; James T Handa; Debasish Sinha
Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.
Journal of cell science 2011;124(Pt 4):523-31.
2011: B Ma; D S McLeod; T Sen; L Asnaghi; Charles G Eberhart; Stacey Hose; Y Lu; M Valapala; F Yang; J. SAMUEL ZIGLER; Debasish Sinha
βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis.
Cell death & disease 2011;2():e217.
2010: R E Neal; C Lin; R Isom; K Vaishnav; J. SAMUEL ZIGLER
Opacification of lenses cultured in the presence of Pb.
Molecular vision 2010;16():2137-45.
2008: Manuel B Datiles; Rafat Ansari; Kwang I Suh; Susan Vitale; George F Reed; J. SAMUEL ZIGLER; Frederick L Ferris
Clinical detection of precataractous lens protein changes using dynamic light scattering.
Archives of ophthalmology 2008;126(12):1687-93.
2008: Debasish Sinha; Andrew Klise; Yuri V Sergeev; Stacey Hose; Imran A Bhutto; Laszlo Hackler; Tanya Malpic-Llanos; Sonia Samtani; Rhonda Grebe; Morton F Goldberg; J Fielding Hejtmancik; Avindra Nath; Donald J Zack; Robert Fariss; D Scott McLeod; Olof H Sundin; Karl W Broman; Gerard A Lutty; J. SAMUEL ZIGLER
betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development.
Molecular and cellular neurosciences 2008;37(1):85-95.
2006: Amber A Smith; Keith Wyatt; Jennifer Vacha; Thomas S Vihtelic; J. SAMUEL ZIGLER; Graeme Wistow; Mason Posner
Gene duplication and separation of functions in alphaB-crystallin from zebrafish (Danio rerio).
The FEBS journal 2006;273(3):481-90.
2006: Peter L Gehlbach; Stacey Hose; Bo Lei; Cheng Zhang; Marisol Cano; M Arora; R Neal; C Barnstable; Morton F Goldberg; J. SAMUEL ZIGLER; Debasish Sinha
Developmental abnormalities in the Nuc1 rat retina: a spontaneous mutation that affects neuronal and vascular remodeling and retinal function.
Neuroscience 2006;137(2):447-61.
2005: Cheng Zhang; Peter L Gehlbach; Celine Gongora; Marisol Cano; Robert Fariss; Stacey Hose; Avindra Nath; W Richard Green; Morton F Goldberg; J. SAMUEL ZIGLER; Debasish Sinha
A potential role for beta- and gamma-crystallins in the vascular remodeling of the eye.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;234(1):36-47.
2005: R Neal; Nukhet Aykin-Burns; Nuran Ercal; J. SAMUEL ZIGLER
Pb2+ exposure alters the lens alpha A-crystallin protein profile in vivo and induces cataract formation in lens organ culture.
Toxicology 2005;212(1):1-9.
2005: Rachel Neal; Frederick A Bettelheim; C Lin; K C Winn; Donita Garland; J. SAMUEL ZIGLER
Alterations in human vitreous humour following cataract extraction.
Experimental eye research 2005;80(3):337-47.
2005: Stacey Hose; J. SAMUEL ZIGLER; Debasish Sinha
A novel rat model to study the functions of macrophages during normal development and pathophysiology of the eye.
Immunology letters 2005;96(2):299-302.
2005: Madhumita P Ghosh; J. SAMUEL ZIGLER
Lack of fiber cell induction stops normal growth of rat lenses in organ culture.
Molecular vision 2005;11():901-8.
2005: Martin J Lizak; J. SAMUEL ZIGLER; Frederick A Bettelheim
Syneretic response to incremental pressures in calf lenses.
Current eye research 2005;30(1):21-5.
2005: Howard M Jernigan Jr; Penny S Blum; Ipsit Chakrabarti; Yin Su; J. SAMUEL ZIGLER
Effects of cataractogenesis on the CDP-choline pathway: increased phospholipid synthesis in lenses from galactosemic rats and 13/N guinea pigs.
Ophthalmic research 2005;37(1):7-12.
2004: Frederick A Bettelheim; J. SAMUEL ZIGLER
Regional mapping of molecular components of human liquid vitreous by dynamic light scattering.
Experimental eye research 2004;79(5):713-8.
2004: Peter H Frederikse; Esther Yun; Hung-Teh Kao; J. SAMUEL ZIGLER; Qian Sun; A Sami Qazi
Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.
Molecular vision 2004;10():794-804.
2004: Rupalatha Maddala; Pei-Feng Deng; Joseph M Costello; Eric F Wawrousek; J. SAMUEL ZIGLER; Vasantha P Rao
Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse.
Laboratory investigation; a journal of technical methods and pathology 2004;84(6):679-92.
2004: P Vasantha Rao; Rupalatha Maddala; Faith John; J. SAMUEL ZIGLER
Expression of nonphagocytic NADPH oxidase system in the ocular lens.
Molecular vision 2004;10():112-21.
2003: J. SAMUEL ZIGLER; Chuan Qin; Toshikazu Kamiya; Murali K Cherukuri; Qiufang Cheng; Santa Tumminia; Paul Russell
Tempol-H inhibits opacification of lenses in organ culture.
Free radical biology & medicine 2003;35(10):1194-202.
2003: Puwat Charukamnoetkanok; James P Brady; Eric F Wawrousek; Charles E Egwuagu; J. SAMUEL ZIGLER; Barbara P Vistica; Scott M Whitcup; Igal Gery
Immunotolerance toward native alphaA-crystallin in knockout mice deficient in the functional protein.
Immunology letters 2003;89(2-3):259-65.
2003: Monique P Gelderman; Puwat Charukamnoetkanok; James P Brady; L Hung; J. SAMUEL ZIGLER; Eric F Wawrousek; Barbara P Vistica; E Fortin; Chi-Chao Chan; Igal Gery
A novel inflammatory eye disease induced by lymphocytes from knockout mice sensitized against the deleted ocular antigen.
Clinical and experimental immunology 2003;133(2):177-81.
2003: Frederick A Bettelheim; Martin J Lizak; J. SAMUEL ZIGLER
Syneretic response of aging normal human lens to pressure.
Investigative ophthalmology & visual science 2003;44(1):258-63.
2002: Frederick A Bettelheim; Martin J Lizak; J. SAMUEL ZIGLER
Relaxographic studies of aging normal human lenses.
Experimental eye research 2002;75(6):695-702.
2002: Vasantha Rao; Eric F Wawrousek; Ernst R Tamm; J. SAMUEL ZIGLER
Rho GTPase inactivation impairs lens growth and integrity.
Laboratory investigation; a journal of technical methods and pathology 2002;82(2):231-9.
2001: Qiufang Cheng; PV Rao; J. SAMUEL ZIGLER
Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.
Experimental eye research 2001;73(2):239-45.
2001: Frederick A Bettelheim; Martin J Lizak; J. SAMUEL ZIGLER
NMR relaxation studies of syneretic response to pressure change in bovine lenses.
Current eye research 2001;22(6):438-45.
2001: Rachel Neal; J. SAMUEL ZIGLER; Frederick A Bettelheim
On the equilibrium between monomeric alpha-lactalbumin and the chaperoning complex of alpha-crystallin.
Biochemical and biophysical research communications 2001;280(1):14-8.
2000: Q Cheng; P Gonzalez; J. SAMUEL ZIGLER
High level of ferritin light chain mRNA in lens.
Biochemical and biophysical research communications 2000;270(2):349-55.
2000: Q Cheng; David Lichtstein; Paul Russell; J. SAMUEL ZIGLER
Use of a lipophilic cation to monitor electrical membrane potential in the intact rat lens.
Investigative ophthalmology & visual science 2000;41(2):482-7.
2000: J K Sun; Takeshi Iwata; J. SAMUEL ZIGLER; Deborah A Carper
Differential gene expression in male and female rat lenses undergoing cataract induction by transforming growth factor-beta (TGF-beta).
Experimental eye research 2000;70(2):169-81.
2000: Peter H Frederikse; J. SAMUEL ZIGLER; PN Farnsworth; D A Carper
Prion protein expression in mammalian lenses.
Current eye research 2000;20(2):137-43.
1999: Frederick A Bettelheim; Rafat Ansari; Q F Cheng; J. SAMUEL ZIGLER
The mode of chaperoning of dithiothreitol-denatured alpha-lactalbumin by alpha-crystallin.
Biochemical and biophysical research communications 1999;261(2):292-7.
1999: Y Wang; H He; J. SAMUEL ZIGLER; Takeshi Iwata; Nobuhiro Ibaraki; Venkat N Reddy; Deborah A Carper
bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line.
Experimental cell research 1999;249(1):123-30.
1999: Peter H Frederikse; PN Farnsworth; J. SAMUEL ZIGLER
Thiamine deficiency in vivo produces fiber cell degeneration in mouse lenses.
Biochemical and biophysical research communications 1999;258(3):703-7.
1999: Pedro Gonzalez; J. SAMUEL ZIGLER; David L Epstein; Teresa Borrás
Identification and isolation of differentially expressed genes from very small tissue samples.
BioTechniques 1999;26(5):884-6, 888-92.
1999: Frederick A Bettelheim; J. SAMUEL ZIGLER
Pressure-induced syneretic response in rhesus monkey lenses.
Investigative ophthalmology & visual science 1999;40(6):1285-8.
1999: David Lichtstein; Talia Levy; Joseph Deutsch; Michael Steinitz; J. SAMUEL ZIGLER; Paul Russell
The effects of digitalis-like compounds on rat lenses.
Investigative ophthalmology & visual science 1999;40(2):407-13.
1999: Deborah A Carper; J K Sun; Takeshi Iwata; J. SAMUEL ZIGLER; Nobuhiro Ibaraki; Li-Ren Lin; V Reddy
Oxidative stress induces differential gene expression in a human lens epithelial cell line.
Investigative ophthalmology & visual science 1999;40(2):400-6.
1998: PV Rao; Timothy A Garrow; F John; Donita Garland; Norman S Millian; J. SAMUEL ZIGLER
Betaine-homocysteine methyltransferase is a developmentally regulated enzyme crystallin in rhesus monkey lens.
The Journal of biological chemistry 1998;273(46):30669-74.
1998: Peter H Frederikse; J. SAMUEL ZIGLER
Presenilin expression in the ocular lens.
Current eye research 1998;17(9):947-52.
1998: Howard M Jernigan; J. SAMUEL ZIGLER; Ying Liu; Penny S Blum; L O Merola; C D Stimbert
Effects of xylose on monkey lenses in organ culture: a model for study of sugar cataracts in a primate.
Experimental eye research 1998;67(1):61-71.
1997: PV Rao; W Gerald Robison; Frederick A Bettelheim; Li-Ren Lin; Venkat N Reddy; J. SAMUEL ZIGLER
Role of small GTP-binding proteins in lovastatin-induced cataracts.
Investigative ophthalmology & visual science 1997;38(11):2313-21.
1997: Frederick A Bettelheim; A C Churchill; J. SAMUEL ZIGLER
On the nature of hereditary cataract in strain 13/N guinea pigs.
Current eye research 1997;16(9):917-24.
1997: PV Rao; P Gonzalez; B Persson; H Jörnvall; Donita Garland; J. SAMUEL ZIGLER
Guinea pig and bovine zeta-crystallins have distinct functional characteristics highlighting replacements in otherwise similar structures.
Biochemistry 1997;36(18):5353-62.
1997: PV Rao; J. SAMUEL ZIGLER; Donita Garland
Analysis of small GTP-binding proteins of the lens by GTP overlay assay reveals the presence of unique GTP-binding proteins associated with fiber cells.
Experimental eye research 1997;64(2):219-27.
1996: T Kamiya; J. SAMUEL ZIGLER
Long-term maintenance of monkey lenses in organ culture: a potential model system for the study of human cataractogenesis.
Experimental eye research 1996;63(4):425-31.
1996: SJ Tumminia; C Chambers; C Qin; J. SAMUEL ZIGLER; Paul Russell
A comparison of antioxidant enzyme activities in organ-cultured rhesus monkey lenses following peroxide challenge.
Current eye research 1996;15(8):845-51.
1996: P Russell; C Qin; D Garland; Y Tabor; J. SAMUEL ZIGLER
RNA and protein synthesis in the primate lens.
Experimental eye research 1996;63(1):121-4.
1996: C Qin; SJ Tumminia; Paul Russell; PV Rao; J. SAMUEL ZIGLER
Investigations into the loss of glutathione from lenses in organ culture.
Current eye research 1996;15(7):719-25.
1996: R W Parks; R E Becker; R F Rippey; D G Gilbert; Jeffery R Matthews; E Kabatay; C S Young; C Vohs; V Danz; P Keim; G T Collins; J. SAMUEL ZIGLER; P G Urycki
Increased regional cerebral glucose metabolism and semantic memory performance in Alzheimer's disease: a pilot double blind transdermal nicotine positron emission tomography study.
Neuropsychology review 1996;6(2):61-79.
1996: Teresa Borrás; E R Tamm; J. SAMUEL ZIGLER
Ocular adenovirus gene transfer varies in efficiency and inflammatory response.
Investigative ophthalmology & visual science 1996;37(7):1282-93.
1996: Peter H Frederikse; Donita Garland; J. SAMUEL ZIGLER; Joram Piatigorsky
Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.
The Journal of biological chemistry 1996;271(17):10169-74.
1996: Marjorie F Lou; Guo-Tong Xu; J. SAMUEL ZIGLER; B York
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Current eye research 1996;15(4):423-32.
1996: Frederick A Bettelheim; J. SAMUEL ZIGLER
Degradation of vimentin in frozen rat lenses.
Ophthalmic research 1996;28(4):219-23.
1995: PV Rao; Q L Huang; J Horwitz; J. SAMUEL ZIGLER
Evidence that alpha-crystallin prevents non-specific protein aggregation in the intact eye lens.
Biochimica et biophysica acta 1995;1245(3):439-47.
1995: P Gonzalez; P V Rao; S B Nuñez; J. SAMUEL ZIGLER
Evidence for independent recruitment of zeta-crystallin/quinone reductase (CRYZ) as a crystallin in camelids and hystricomorph rodents.
Molecular biology and evolution 1995;12(5):773-81.
1995: J Jimenez-Asensio; P Gonzalez; J. SAMUEL ZIGLER; D L Garland
Glyceraldehyde 3-phosphate dehydrogenase is an enzyme-crystallin in diurnal geckos of the genus Phelsuma.
Biochemical and biophysical research communications 1995;209(3):796-802.
1995: Mohan Chintalagiri Rao; C Qin; W G Robison; J. SAMUEL ZIGLER
Effect of smoke condensate on the physiological integrity and morphology of organ cultured rat lenses.
Current eye research 1995;14(4):295-301.
1995: Frederick A Bettelheim; C Qin; J. SAMUEL ZIGLER
Calcium cataract: a model for optical anisotropy fluctuations.
Experimental eye research 1995;60(2):153-7.
1994: Bengt Persson; J. SAMUEL ZIGLER; Hans Jörnvall
A super-family of medium-chain dehydrogenases/reductases (MDR). Sub-lines including zeta-crystallin, alcohol and polyol dehydrogenases, quinone oxidoreductase enoyl reductases, VAT-1 and other proteins.
European journal of biochemistry / FEBS 1994;226(1):15-22.
1994: C Heinzmann; T L Kojis; P Gonzalez; P V Rao; J. SAMUEL ZIGLER; Mihael H Polymeropoulos; I Klisak; RS Sparkes; T Mohandas; J B Bateman
Assignment of the zeta-crystallin gene (CRYZ) to human chromosome 1p22-p31 and identification of restriction fragment length polymorphisms.
Genomics 1994;23(2):403-7.
1994: P Gonzalez; PV Rao; J. SAMUEL ZIGLER
Organization of the human zeta-crystallin/quinone reductase gene (CRYZ).
Genomics 1994;21(2):317-24.
1994: PV Rao; J Horwitz; J. SAMUEL ZIGLER
Chaperone-like activity of alpha-crystallin. The effect of NADPH on its interaction with zeta-crystallin.
The Journal of biological chemistry 1994;269(18):13266-72.
1994: SJ Tumminia; C Qin; J. SAMUEL ZIGLER; Paul Russell
The integrity of mammalian lenses in organ culture.
Experimental eye research 1994;58(3):367-74.
1994: P Gonzalez; C Hernández-Calzadilla; PV Rao; Ignacio R Rodriguez; J. SAMUEL ZIGLER; Teresa Borrás
Comparative analysis of the zeta-crystallin/quinone reductase gene in guinea pig and mouse.
Molecular biology and evolution 1994;11(2):305-15.
1994: X L Cui; C Qin; J. SAMUEL ZIGLER
Residual EDTA bound by lens crystallins accounts for their reported resistance to copper-catalyzed oxidative damage.
Archives of biochemistry and biophysics 1994;308(1):207-13.
1993: SJ Tumminia; PV Rao; J. SAMUEL ZIGLER; Paul Russell
Xenobiotic induction of quinone oxidoreductase activity in lens epithelial cells.
Biochimica et biophysica acta 1993;1203(2):251-9.
1993: Hans Jörnvall; Bengt Persson; G C Du Bois; G C Lavers; J H Chen; P Gonzalez; P V Rao; J. SAMUEL ZIGLER
Zeta-crystallin versus other members of the alcohol dehydrogenase super-family. Variability as a functional characteristic.
FEBS letters 1993;322(3):240-4.
1993: Mohan Chintalagiri Rao; J. SAMUEL ZIGLER
Are crystallins designed for high intracellular stability?
Experimental eye research 1993;56(5):615-9.
1993: P Gonzalez; PV Rao; J. SAMUEL ZIGLER
Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver.
Biochemical and biophysical research communications 1993;191(3):902-7.
1993: PV Rao; J Horwitz; J. SAMUEL ZIGLER
Alpha-crystallin, a molecular chaperone, forms a stable complex with carbonic anhydrase upon heat denaturation.
Biochemical and biophysical research communications 1993;190(3):786-93.
1993: D C Lee; P Gonzalez; PV Rao; J. SAMUEL ZIGLER; Graeme Wistow
Carbonyl-metabolizing enzymes and their relatives recruited as structural proteins in the eye lens.
Advances in experimental medicine and biology 1993;328():159-68.
1992: PV Rao; J. SAMUEL ZIGLER
Purification and characterization of zeta-crystallin/quinone reductase from guinea pig liver.
Biochimica et biophysica acta 1992;1117(3):315-20.
1992: Ignacio R Rodriguez; P Gonzalez; J. SAMUEL ZIGLER; Teresa Borrás
A guinea-pig hereditary cataract contains a splice-site deletion in a crystallin gene.
Biochimica et biophysica acta 1992;1180(1):44-52.
1992: Mohan Chintalagiri Rao; J. SAMUEL ZIGLER
Levels of reduced pyridine nucleotides and lens photodamage.
Photochemistry and photobiology 1992;56(4):523-8.
1992: Manuel B Datiles; D J Schumer; J. SAMUEL ZIGLER; P Russell; L Anderson; Donita Garland
Two-dimensional gel electrophoretic analysis of human lens proteins.
Current eye research 1992;11(7):669-77.
1992: X Y Du; P Linser; Paul Russell; J. SAMUEL ZIGLER
Carbonic anhydrase III is expressed in bovine lens.
Current eye research 1992;11(5):475-8.
1992: P V Rao; J. SAMUEL ZIGLER
Mutant zeta-crystallin from guinea-pig hereditary cataracts has altered structural and enzymatic properties.
Experimental eye research 1992;54(4):627-30.
1992: P Rao; J. SAMUEL ZIGLER
Quinone induced stimulation of hexose monophosphate shunt activity in the guinea pig lens: role of zeta-crystallin.
Biochimica et biophysica acta 1992;1116(1):75-81.
1992: E P Roquemore; Anne Dell; Howard R Morris; Maria Panico; Andrew J Reason; L A Savoy; Graeme Wistow; J. SAMUEL ZIGLER; B J Earles; Gerald W Hart
Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine.
The Journal of biological chemistry 1992;267(1):555-63.
1992: PV Rao; Murali K Cherukuri; J. SAMUEL ZIGLER
Identification and characterization of the enzymatic activity of zeta-crystallin from guinea pig lens. A novel NADPH:quinone oxidoreductase.
The Journal of biological chemistry 1992;267(1):96-102.
1992: Guo-Tong Xu; J. SAMUEL ZIGLER; Marjorie F Lou
Establishment of a naphthalene cataract model in vitro.
Experimental eye research 1992;54(1):73-81.
1992: Guo-Tong Xu; J. SAMUEL ZIGLER; Marjorie F Lou
The possible mechanism of naphthalene cataract in rat and its prevention by an aldose reductase inhibitor (ALO1576).
Experimental eye research 1992;54(1):63-72.
1992: P Russell; J. SAMUEL ZIGLER
Analysis of the effect of eye bank storage conditions on primate lens epithelium.
Experimental eye research 1992;54(1):153-5.
1991: Murali K Cherukuri; S Uppuluri; Péter Riesz; J. SAMUEL ZIGLER; D Balasubramanian
A study of the photodynamic efficiencies of some eye lens constituents.
Photochemistry and photobiology 1991;54(1):51-8.
1991: Donita Garland; PV Rao; Antonella Del Corso; Umberto Mura; J. SAMUEL ZIGLER
zeta-Crystallin is a major protein in the lens of Camelus dromedarius.
Archives of biochemistry and biophysics 1991;285(1):134-6.
1991: J. SAMUEL ZIGLER; PV Rao
Enzyme/crystallins and extremely high pyridine nucleotide levels in the eye lens.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(2):223-5.
1991: PV Rao; J. SAMUEL ZIGLER
Zeta-crystallin from guinea pig lens is capable of functioning catalytically as an oxidoreductase.
Archives of biochemistry and biophysics 1991;284(1):181-5.
1991: P Russell; T Yamada; Guo-Tong Xu; Donita Garland; J. SAMUEL ZIGLER
Effects of naphthalene metabolites on cultured cells from eye lens.
Free radical biology & medicine 1991;10(5):255-61.
1990: T L O'Keefe; H H Hess; J. SAMUEL ZIGLER; T Kuwabara; J J Knapka
Prevention of cataracts in pink-eyed RCS rats by dark rearing.
Experimental eye research 1990;51(5):509-17.
1990: Dorairajan Balasubramanian; X Du; J. SAMUEL ZIGLER
The reaction of singlet oxygen with proteins, with special reference to crystallins.
Photochemistry and photobiology 1990;52(4):761-8.
1990: J. SAMUEL ZIGLER
Animal models for the study of maturity-onset and hereditary cataract.
Experimental eye research 1990;50(6):651-7.
1990: PV Rao; J. SAMUEL ZIGLER
Extremely high levels of NADPH in guinea pig lens: correlation with zeta-crystallin concentration.
Biochemical and biophysical research communications 1990;167(3):1221-8.
1990: Q L Huang; X Y Du; S H Stone; D F Amsbaugh; Manuel B Datiles; T S Hu; J. SAMUEL ZIGLER
Association of hereditary cataracts in strain 13/N guinea-pigs with mutation of the gene for zeta-crystallin.
Experimental eye research 1990;50(3):317-25.
1990: AM Geller; J. SAMUEL ZIGLER; H M Jernigan
Serine hydroxymethyltransferase: evidence for its presence in human, monkey and rat lenses.
Experimental eye research 1990;50(2):149-55.
1989: H M Jernigan; J. SAMUEL ZIGLER
Phosphorylcholine and phosphorylethanolamine in human and rhesus monkey lenses.
Experimental eye research 1989;49(5):901-9.
1989: J. SAMUEL ZIGLER; V A Lucas; X Y Du
Rhesus monkey lens as an in vitro model for studying oxidative stress.
Investigative ophthalmology & visual science 1989;30(10):2195-9.
1989: M F Lou; Qing Ling Huang; J. SAMUEL ZIGLER
Effect of opacification and pigmentation on human lens protein thiol/disulfide and solubility.
Current eye research 1989;8(9):883-90.
1989: J. SAMUEL ZIGLER; Q L Huang; X Y Du
Oxidative modification of lens crystallins by H2O2 and chelated iron.
Free radical biology & medicine 1989;7(5):499-505.
1988: Venkat N Reddy; Li-Ren Lin; T Arita; J. SAMUEL ZIGLER; Q L Huang
Crystallins and their synthesis in human lens epithelial cells in tissue culture.
Experimental eye research 1988;47(3):465-78.
1988: Frederick A Bettelheim; J. SAMUEL ZIGLER
Preferential interaction among lens proteins as evidenced from accessibility of crystallins to ammonia gas.
Experimental eye research 1988;47(2):227-36.
1988: V A Lucas; J. SAMUEL ZIGLER
Identification of the monkey lens glucose transporter by photoaffinity labelling with cytochalasin B.
Investigative ophthalmology & visual science 1988;29(4):630-5.
1988: D Garland; Paul Russell; J. SAMUEL ZIGLER
The oxidative modification of lens proteins.
Basic life sciences 1988;49():347-52.
1987: J L Lepe-Zuniga; J. SAMUEL ZIGLER; I Gery
Toxicity of light-exposed Hepes media.
Journal of immunological methods 1987;103(1):145.
1987: Frederick A Bettelheim; J. SAMUEL ZIGLER; V N Reddy
Accessibility of low-molecular-weight crystallins to ammonia and hydrogen chloride gases.
Experimental eye research 1987;45(2):271-9.
1987: V A Lucas; J. SAMUEL ZIGLER
Transmembrane glucose carriers in the monkey lens. Quantitation and regional distribution as determined by cytochalasin B binding to lens membranes.
Investigative ophthalmology & visual science 1987;28(8):1404-12.
1987: Paul Russell; D Garland; J. SAMUEL ZIGLER; S O Meakin; Lap-Chee Tsui; M L Breitman
Aging effects of vitamin C on a human lens protein produced in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1987;1(1):32-5.
1987: H M Jernigan; J. SAMUEL ZIGLER
Metabolism of glutamine and glutamate in monkey lens.
Experimental eye research 1987;44(6):871-6.
1987: Q L Huang; P Russell; S H Stone; J. SAMUEL ZIGLER
Zeta-crystallin, a novel lens protein from the guinea pig.
Current eye research 1987;6(5):725-32.
1986: D Garland; J. SAMUEL ZIGLER; J Kinoshita
Structural changes in bovine lens crystallins induced by ascorbate, metal, and oxygen.
Archives of biochemistry and biophysics 1986;251(2):771-6.
1986: J. SAMUEL ZIGLER; P Russell; J Horwitz; V N Reddy; J H Kinoshita
Further studies on low molecular weight crystallins: relationship between the bovine beta s, the human 24kD protein and the gamma-crystallins.
Current eye research 1986;5(5):395-401.
1986: H W Korf; A Oksche; P Ekström; I Gery; J. SAMUEL ZIGLER; David Klein
Pinealocyte projections into the mammalian brain revealed with S-antigen antiserum.
Science (New York, N.Y.) 1986;231(4739):735-7.
1986: H W Korf; David Klein; J. SAMUEL ZIGLER; I Gery; W Schachenmayr
S-antigen-like immunoreactivity in a human pineocytoma.
Acta neuropathologica 1986;69(1-2):165-7.
1985: J L Lepe-Zuniga; J. SAMUEL ZIGLER; M L Zimmerman; I Gery
Differences between intra- and extracellular interleukin-1.
Molecular immunology 1985;22(12):1387-92.
1985: J L Lepe-Zuniga; J. SAMUEL ZIGLER; I Gery
Dual effect of phorbol myristate acetate (PMA) on murine thymocyte cultures.
Immunobiology 1985;170(4):327-37.
1985: J. SAMUEL ZIGLER; H M Jernigan; D Garland; V N Reddy
The effects of "oxygen radicals" generated in the medium on lenses in organ culture: inhibition of damage by chelated iron.
Archives of biochemistry and biophysics 1985;241(1):163-72.
1985: J. SAMUEL ZIGLER; H H Hess
Cataracts in the Royal College of Surgeons rat: evidence for initiation by lipid peroxidation products.
Experimental eye research 1985;41(1):67-76.
1985: J. SAMUEL ZIGLER; J L Lepe-Zuniga; B Vistica; I Gery
Analysis of the cytotoxic effects of light-exposed HEPES-containing culture medium.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1985;21(5):282-7.
1985: J. SAMUEL ZIGLER; P Russell; Larry Takemoto; S J Schwab; J S Hansen; Joseph Horwitz; J H Kinoshita
Partial characterization of three distinct populations of human gamma-crystallins.
Investigative ophthalmology & visual science 1985;26(4):525-31.
1985: Larry Takemoto; J S Hansen; J. SAMUEL ZIGLER; Joseph Horwitz
Characterization of polypeptides from human nuclear cataracts by Western blot analysis.
Experimental eye research 1985;40(2):205-12.
1985: H W Korf; M Møller; I Gery; J. SAMUEL ZIGLER; D C Klein
Immunocytochemical demonstration of retinal S-antigen in the pineal organ of four mammalian species.
Cell and tissue research 1985;239(1):81-5.
1984: P Russell; J. SAMUEL ZIGLER; V Reddy
The development of a monoclonal antibody to a human gamma crystallin.
Current eye research 1984;3(11):1329-35.
1984: J. SAMUEL ZIGLER; M Mochizuki; T Kuwabara; I Gery
Purification of retinal S-antigen to homogeneity by the criterion of gel electrophoresis silver staining.
Investigative ophthalmology & visual science 1984;25(8):977-80.
1984: R S Bodaness; M Leclair; J. SAMUEL ZIGLER
An analysis of the H2O2-mediated crosslinking of lens crystallins catalyzed by the heme-undecapeptide from cytochrome c.
Archives of biochemistry and biophysics 1984;231(2):461-9.
1984: J. SAMUEL ZIGLER; J D Goosey
Singlet oxygen as a possible factor in human senile nuclear cataract development.
Current eye research 1984;3(1):59-65.
1984: M Mochizuki; J. SAMUEL ZIGLER; P Russell; I Gery
Cytostatic and cytolytic activities of macrophages regulation by prostaglandins.
Cellular immunology 1984;83(1):34-42.
1983: J. SAMUEL ZIGLER; R S Bodaness; I Gery; J H Kinoshita
Effects of lipid peroxidation products on the rat lens in organ culture: a possible mechanism of cataract initiation in retinal degenerative disease.
Archives of biochemistry and biophysics 1983;225(1):149-56.
1983: R S Bodaness; J. SAMUEL ZIGLER
The rapid H2O2-mediated nonphotodynamic crosslinking of lens crystallins generated by the heme-undecapeptide from cytochrome C: potential implications for cataractogenesis in man.
Biochemical and biophysical research communications 1983;113(2):592-7.
1983: J. SAMUEL ZIGLER; I Gery; D Kessler; J H Kinoshita
Macrophage mediated damage to rat lenses in culture: a possible model for uveitis-associated cataract.
Investigative ophthalmology & visual science 1983;24(5):651-4.
1982: J. SAMUEL ZIGLER; H M Jernigan; N S Perlmutter; J H Kinoshita
Photodynamic cross-linking of polypeptides in intact rat lens.
Experimental eye research 1982;35(3):239-49.
1982: M Mochizuki; J. SAMUEL ZIGLER; P Russell; I Gery
Serum proteins neutralize the toxic effect of lysophosphatidyl choline.
Current eye research 1982;2(9):621-4.
1981: I Gery; J. SAMUEL ZIGLER; R O Brady; J A Barranger
Selective effects of glucocerebroside (Gaucher's storage material) on macrophage cultures.
The Journal of clinical investigation 1981;68(5):1182-9.
1981: J. SAMUEL ZIGLER; J Horwitz
Immunochemical studies on the major intrinsic polypeptides from human lens membrane.
Investigative ophthalmology & visual science 1981;21(1 Pt 1):46-51.
1981: J. SAMUEL ZIGLER; J D Goosey
Photosensitized oxidation in the ocular lens: evidence for photosensitizers endogenous to the human lens.
Photochemistry and photobiology 1981;33(6):869-74.
1981: J D Goosey; J. SAMUEL ZIGLER; I B Matheson; J H Kinoshita
Effects of singlet oxygen on human lens crystallins in vitro.
Investigative ophthalmology & visual science 1981;20(5):679-83.
1981: P Russell; S Uga; J. SAMUEL ZIGLER; M Kaiser-Kupfer; T Kuwabara
Studies using human lenses from a family displaying hereditary congenital cataracts.
Vision research 1981;21(1):169-72.
1981: J. SAMUEL ZIGLER; J Horwitz; J H Kinoshita
Studies on the low molecular weight proteins of human lens.
Experimental eye research 1981;32(1):21-30.
1980: J. SAMUEL ZIGLER; D Carper; P Russell; J H Kinoshita
Analysis of some immunochemical properties of human beta-crystallin by radioimmunoassay.
Experimental eye research 1980;31(4):389-97.
1980: J. SAMUEL ZIGLER; J Horwitz; J H Kinoshita
Human beta-crystallin. I. Comparative studies on the beta 1, beta 2 and beta 3-crystallins.
Experimental eye research 1980;31(1):41-55.
1980: J D Goosey; J. SAMUEL ZIGLER; J H Kinoshita
Cross-linking of lens crystallins in a photodynamic system: a process mediated by singlet oxygen.
Science (New York, N.Y.) 1980;208(4449):1278-80.
1979: P F Kador; J. SAMUEL ZIGLER; J H Kinoshita
Alterations of lens protein synthesis in galactosemic rats.
Investigative ophthalmology & visual science 1979;18(7):696-702.
1979: J Horwitz; N P Robertson; M M Wong; J. SAMUEL ZIGLER; J H Kinoshita
Some properties of lens plasma membrane polypeptides isolated from normal human lenses.
Experimental eye research 1979;28(3):359-65.
1978: J. SAMUEL ZIGLER
Age-related changes in the polypeptide composition of beta-crystallin from bovine lens.
Experimental eye research 1978;26(5):537-46.
1978: P M Masters; J L Bada; J. SAMUEL ZIGLER
Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(3):1204-8.
1977: P M Masters; J L Bada; J. SAMUEL ZIGLER
Aspartic acid racemisation in the human lens during ageing and in cataract formation.
Nature 1977;268(5615):71-3.
1977: J. SAMUEL ZIGLER; M E Mauney; J B Sidbury
Age-related changes in the free amino acid pool of rat lens.
Investigative ophthalmology & visual science 1977;16(2):171-5.
1976: J. SAMUEL ZIGLER; J B Sidbury
Studies on beta-crystallin from primate lens.
Investigative ophthalmology 1976;15(8):673-7.
1976: J. SAMUEL ZIGLER; J B Sidbury
A comparative study of the beta-crystallins of four sub-mammalian species.
Comparative biochemistry and physiology. B, Comparative biochemistry 1976;55(1):19-24.
1976: J. SAMUEL ZIGLER; J B Sidbury
A comparative study of beta-crystallin from six mammals.
Comparative biochemistry and physiology. B, Comparative biochemistry 1976;53(3):349-55.
1973: V D Rowe; J. SAMUEL ZIGLER; A E Andersen; J B Sidbury; G Guroff
Some characteristics of the p-chlorophenylalanine-induced cataract.
Experimental eye research 1973;17(3):245-50.
1973: J. SAMUEL ZIGLER; J B Sidbury
Structure of calf lens beta-crystallins.
Experimental eye research 1973;16(3):207-14.