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John Bucher

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TOP 3
Linda S Birnbaum; John R Bucher; Kristina A Thayer; Mary S Wolfe
Implementing systematic review at the national toxicology program: status and next steps.
John R Bucher
Regulatory forum opinion piece: Tox21 and toxicologic pathology.
Linda S Birnbaum; John R Bucher; Gwen Collman; Anne F Johnson; Thaddeus T Schug; Darryl C Zeldin; Jerrold J Heindel
Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A.

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All Publications

2013: Linda S Birnbaum; John R Bucher; Kristina A Thayer; Mary S Wolfe
Implementing systematic review at the national toxicology program: status and next steps.
Environmental health perspectives 2013;121(4):A108-9.
2013: John R Bucher
Regulatory forum opinion piece: Tox21 and toxicologic pathology.
Toxicologic pathology 2013;41(1):125-7.
2012: Linda S Birnbaum; John R Bucher; Gwen Collman; Anne F Johnson; Thaddeus T Schug; Darryl C Zeldin; Jerrold J Heindel
Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A.
Environmental health perspectives 2012;120(12):1640-4.
2012: Kristina A Thayer; Jerrold J Heindel; John R Bucher; Michael A Gallo
Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review.
Environmental health perspectives 2012;120(6):779-89.
2011: Stephanie A Lahousse; T Masinde; D Olson; Y Rebolloso; John R Bucher; J Collins; Mark Hoenerhoff; Hue-Hua L Hong; Takatoshi Koujitani; Kenneth B Tomer; Thai-Vu T Ton; Robert C Sills
Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.
Veterinary pathology 2011;48(4):875-84.
2011: John R Bucher; Kristina A Thayer; Linda S Birnbaum
The Office of Health Assessment and Translation: a problem-solving resource for the National Toxicology Program.
Environmental health perspectives 2011;119(5):A196-7.
2010: Angela King-Herbert; Robert C Sills; John R Bucher
Commentary: update on animal models for NTP studies.
Toxicologic pathology 2010;38(1):180-1.
2009: Nigel J Walker; John R Bucher
A 21st century paradigm for evaluating the health hazards of nanoscale materials?
Toxicological sciences : an official journal of the Society of Toxicology 2009;110(2):251-4.
2009: J M Sanders; John R Bucher; John Peckham; Grace E Kissling; milton hejtmancik; Rajendra S Chhabra
Carcinogenesis studies of cresols in rats and mice.
Toxicology 2009;257(1-2):33-9.
2008: Matthew D Stout; Grace E Kissling; Fernando A Suárez; David E Malarkey; Ronald A Herbert; John R Bucher
Influence of Helicobacter hepaticus infection on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice.
Toxicologic pathology 2008;36(6):783-94.
2008: Matthew D Stout; Ronald A Herbert; Grace E Kissling; Fernando Suarez; Joseph H Roycroft; Rajendra S Chhabra; John R Bucher
Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure.
Toxicology 2008;244(2-3):209-19.
2008: Ronald L Melnick; Kristina A Thayer; John R Bucher
Conflicting views on chemical carcinogenesis arising from the design and evaluation of rodent carcinogenicity studies.
Environmental health perspectives 2008;116(1):130-5.
2007: Adriana M Doi; Georgette Hill; John C Seely; James R Hailey; Grace E Kissling; John R Bucher
alpha 2u-globulin nephropathy and renal tumors in national toxicology program studies.
Toxicologic pathology 2007;35(4):533-40.
2007: M C Rhodes; John R Bucher; John Peckham; Grace E Kissling; milton hejtmancik; Rajendra S Chhabra
Carcinogenesis studies of benzophenone in rats and mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(5):843-51.
2006: Nigel J Walker; Michael E Wyde; Lawrence J Fischer; Abraham Nyska; John R Bucher
Comparison of chronic toxicity and carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 2-year bioassays in female Sprague-Dawley rats.
Molecular nutrition & food research 2006;50(10):934-44.
2005: Nancy R Bordelon; Rajendra S Chhabra; John R Bucher
A review of evidence from short-term studies leading to the prediction that diazoaminobenzene (1,3-diphenyltriazine) is a carcinogen.
Journal of applied toxicology : JAT 2005;25(6):514-21.
2005: Adriana M Doi; Richard D Irwin; John R Bucher
Influence of functional group substitutions on the carcinogenicity of anthraquinone in rats and mice: analysis of long-term bioassays by the National Cancer Institute and the National Toxicology Program.
Journal of toxicology and environmental health. Part B, Critical reviews 2005;8(2):109-26.
2005: Nigel J Walker; Patrick W Crockett; Abraham Nyska; Amy E Brix; Micheal P Jokinen; Donald M Sells; James R Hailey; Micheal Easterling; Joseph K Haseman; Ming Yin; Michael E Wyde; John R Bucher; Christopher Portier
Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds".
Environmental health perspectives 2005;113(1):43-8.
2004: John R Bucher; Christopher Portier
Human carcinogenic risk evaluation, Part V: The national toxicology program vision for assessing the human carcinogenic hazard of chemicals.
Toxicological sciences : an official journal of the Society of Toxicology 2004;82(2):363-6.
2004: Michelle J Hooth; Ronald A Herbert; Joseph K Haseman; Denise P Orzech; Jerry D Johnson; John R Bucher
Toxicology and carcinogenesis studies of dipropylene glycol in rats and mice.
Toxicology 2004;204(2-3):123-40.
2004: Michelle J Hooth; Robert C Sills; Leo T Burka; Joseph K Haseman; K L Witt; Denise P Orzech; Alfred F Fuciarelli; S W Graves; Jerry D Johnson; John R Bucher
Toxicology and carcinogenesis studies of microencapsulated trans-cinnamaldehyde in rats and mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(11):1757-68.
2004: Michael E Wyde; Angelique P J M Braen; milton hejtmancik; Jerry D Johnson; John D Toft; James C Blake; Stephen D Cooper; Joel Mahler; Molly K Vallant; John R Bucher; Nigel J Walker
Oral and dermal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces cutaneous papillomas and squamous cell carcinomas in female hemizygous Tg.AC transgenic mice.
Toxicological sciences : an official journal of the Society of Toxicology 2004;82(1):34-45.
2004: Adriana M Doi; Joseph H Roycroft; Ronald A Herbert; Joseph K Haseman; James R Hailey; Billy J Chou; Jeffrey A Dill; Sondra L Grumbein; Rodney A Miller; Roger A Renne; John R Bucher
Inhalation toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether in rats and mice.
Toxicology 2004;199(1):1-22.
2003: Rajendra S Chhabra; John R Bucher; Mary Wolfe; Christopher Portier
Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview.
International journal of hygiene and environmental health 2003;206(4-5):437-45.
2003: Nancy B Ress; Billy J Chou; Roger A Renne; Jeffrey A Dill; Rodney A Miller; Joseph H Roycroft; James R Hailey; Joseph K Haseman; John R Bucher
Carcinogenicity of inhaled vanadium pentoxide in F344/N rats and B6C3F1 mice.
Toxicological sciences : an official journal of the Society of Toxicology 2003;74(2):287-96.
2003: Nancy B Ress; James R Hailey; Robert R Maronpot; John R Bucher; Gregory S Travlos; Joseph K Haseman; Denise P Orzech; Jerry D Johnson; milton hejtmancik
Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(2):198-206.
2002: John R Bucher
The National Toxicology Program rodent bioassay: designs, interpretations, and scientific contributions.
Annals of the New York Academy of Sciences 2002;982():198-207.
2002: Nancy B Ress; Kristine L Witt; Jing Xu; Joseph K Haseman; John R Bucher
Micronucleus induction in mice exposed to diazoaminobenzene or its metabolites, benzene and aniline: implications for diazoaminobenzene carcinogenicity.
Mutation research 2002;521(1-2):201-8.
2002: Burhan I Ghanayem; Abraham Nyska; Joseph K Haseman; John R Bucher
Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(1):59-68.
2001: Kamal Abdo; Michael L Cunningham; M L Snell; Ronald A Herbert; Gregory S Travlos; S R Eldridge; John R Bucher
14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(4):303-16.
2001: Rajendra S Chhabra; Ronald A Herbert; John R Bucher; Gregory S Travlos; Jerry D Johnson; milton hejtmancik
Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice.
Toxicological sciences : an official journal of the Society of Toxicology 2001;60(1):28-37.
2001: WC Eastin; JH Mennear; Raymond W Tennant; Raymond Stoll; D G Branstetter; John R Bucher; B McCullough; R L Binder; Judson W Spalding; Joel Mahler
Tg.AC genetically altered mouse: assay working group overview of available data.
Toxicologic pathology 2001;29 Suppl():60-80.
2000: AP van Birgelen; Billy J Chou; Roger A Renne; Sondra L Grumbein; Joseph H Roycroft; James R Hailey; John R Bucher
Effects of glutaraldehyde in a 2-year inhalation study in rats and mice.
Toxicological sciences : an official journal of the Society of Toxicology 2000;55(1):195-205.
2000: John R Bucher
Doses in rodent cancer studies: sorting fact from fiction.
Drug metabolism reviews 2000;32(2):153-63.
1999: John R Bucher; James R Hailey; J R Roycroft; Joseph K Haseman; Robert C Sills; Sondra L Grumbein; P W Mellick; Billy J Chou
Inhalation toxicity and carcinogenicity studies of cobalt sulfate.
Toxicological sciences : an official journal of the Society of Toxicology 1999;49(1):56-67.
1999: AP van Birgelen; CD Hébert; ML Wenk; L K Grimes; Robert Chapin; Gregory S Travlos; Joel Mahler; John R Bucher
Toxicity of 3,3',4,4'-tetrachloroazoxybenzene in rats and mice.
Toxicology and applied pharmacology 1999;156(3):206-21.
1999: AP van Birgelen; CD Hébert; ML Wenk; L K Grimes; Robert Chapin; Joel Mahler; Gregory S Travlos; John R Bucher
Toxicity of 3,3',4,4'-tetrachloroazobenzene in rats and mice.
Toxicology and applied pharmacology 1999;156(2):147-59.
1999: Rajendra S Chhabra; R M Maronpot; John R Bucher; Joseph K Haseman; John D Toft; milton hejtmancik
Toxicology and carcinogenesis studies of pentachlorophenol in rats.
Toxicological sciences : an official journal of the Society of Toxicology 1999;48(1):14-20.
1998: John R Bucher; George W Lucier
Current approaches toward chemical mixture studies at the National Institute of Environmental Health Sciences and the U.S. National Toxicology Program.
Environmental health perspectives 1998;106 Suppl 6():1295-8.
1998: John R Bucher
Update on national toxicology program (NTP) assays with genetically altered or "transgenic" mice.
Environmental health perspectives 1998;106(10):619-21.
1998: James R Hailey; Joseph K Haseman; John R Bucher; A E Radovsky; David E Malarkey; R T Miller; Abraham Nyska; Robert R Maronpot
Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve National Toxicology Program two-year carcinogenesis studies.
Toxicologic pathology 1998;26(5):602-11.
1998: WC Eastin; Joseph K Haseman; Joel Mahler; John R Bucher
The National Toxicology Program evaluation of genetically altered mice as predictive models for identifying carcinogens.
Toxicologic pathology 1998;26(4):461-73.
1998: James M Mathews; Amy S Etheridge; James H Raymer; Sherry R Black; D W Pulliam; John R Bucher
Selective inhibition of cytochrome P450 2E1 in vivo and in vitro with trans-1,2-dichloroethylene.
Chemical research in toxicology 1998;11(7):778-85.
1998: John R Bucher; Joseph K Haseman; Ronald A Herbert; milton hejtmancik; MJ Ryan
Toxicity and carcinogenicity studies of oxazepam in the Fischer 344 rat.
Toxicological sciences : an official journal of the Society of Toxicology 1998;42(1):1-12.
1998: Michael L Cunningham; John R Bucher
Pharmacodynamic responses of F344 rats to the mouse hepatocarcinogen oxazepam in a 90-day feed study.
Toxicology and applied pharmacology 1998;149(1):41-8.
1997: James M Mathews; James H Raymer; Amy S Etheridge; G R Velez; John R Bucher
Do endogenous volatile organic chemicals measured in breath reflect and maintain CYP2E1 levels in vivo?
Toxicology and applied pharmacology 1997;146(2):255-60.
1997: Lorenzo Tomatis; James Huff; Irva Hertz-Picciotto; Dale P Sandler; John R Bucher; P Boffetta; Olav Axelson; Aaron Blair; J Taylor; Leslie T Stayner; J Carl Barrett
Avoided and avoidable risks of cancer.
Carcinogenesis 1997;18(1):97-105.
1996: John R Bucher; Christopher Portier; J I Goodman; E M Faustman; George W Lucier
Workshop overview. National Toxicology Program Studies: principles of dose selection and applications to mechanistic based risk assessment.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;31(1):1-8.
1996: Po C Chan; Robert C Sills; A G Braun; J K Haseman; John R Bucher
Toxicity and carcinogenicity of delta 9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;30(1):109-17.
1996: Gregory S Travlos; Joel Mahler; H A Ragan; Billy J Chou; John R Bucher
Thirteen-week inhalation toxicity of 2- and 4-chloronitrobenzene in F344/N rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;30(1):75-92.
1995: John R Bucher; G N Rao; Kamal Abdo; F Kari; George W Lucier
Diet and test animals.
Science (New York, N.Y.) 1995;270(5241):1421-2.
1995: John R Bucher; Daniel L Morgan; B Adkins; Gregory S Travlos; Barbara J Davis; R Morris; Michael R Elwell
Early changes in sex hormones are not evident in mice exposed to the uterine carcinogens chloroethane or bromoethane.
Toxicology and applied pharmacology 1995;130(1):169-73.
1994: P C Chan; Joel Mahler; John R Bucher; Gregory S Travlos; J B Reid
Toxicity and carcinogenicity of riddelliine following 13 weeks of treatment to rats and mice.
Toxicon : official journal of the International Society on Toxinology 1994;32(8):891-908.
1994: John R Bucher; C C Shackelford; J K Haseman; J D Johnson; P J Kurtz; R L Persing
Carcinogenicity studies of oxazepam in mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;23(2):280-97.
1994: Theodora R Devereux; C M White; Robert C Sills; John R Bucher; Robert R Maronpot; M W Anderson
Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1 mice exposed to oxazepam in the diet.
Carcinogenesis 1994;15(5):1083-7.
1994: June K Dunnick; Michael R Elwell; John R Bucher
Comparative toxicities of o-, m-, and p-nitrotoluene in 13-week feed studies in F344 rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;22(3):411-21.
1994: ML Cunningham; Robert R Maronpot; M Thompson; John R Bucher
Early responses of the liver of B6C3F1 mice to the hepatocarcinogen oxazepam.
Toxicology and applied pharmacology 1994;124(1):31-8.
1994: R L Melnick; Joel Mahler; John R Bucher; M Hejtmancik; A Singer; R L Persing
Toxicity of diethanolamine. 2. Drinking water and topical application exposures in B6C3F1 mice.
Journal of applied toxicology : JAT 1994;14(1):11-9.
1994: R L Melnick; Joel Mahler; John R Bucher; M Thompson; M Hejtmancik; M J Ryan; L E Mezza
Toxicity of diethanolamine. 1. Drinking water and topical application exposures in F344 rats.
Journal of applied toxicology : JAT 1994;14(1):1-9.
1993: C D Hébert; Michael R Elwell; Gregory S Travlos; C J Fitz; John R Bucher
Subchronic toxicity of cupric sulfate administered in drinking water and feed to rats and mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;21(4):461-75.
1993: Rajendra S Chhabra; John R Bucher; J K Haseman; Michael R Elwell; P J Kurtz; B D Carlton
Comparative carcinogenicity of polybrominated biphenyls with or without perinatal exposure in rats and mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;21(4):451-60.
1993: Rajendra S Chhabra; John R Bucher; J K Haseman; Michael R Elwell; P J Kurtz; B D Carlton
Comparative carcinogenicity of 5,5-diphenylhydantoin with or without perinatal exposure in rats and mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;21(2):174-86.
1993: C D Hébert; Michael R Elwell; Gregory S Travlos; E Zeiger; John E French; John R Bucher
Inhalation toxicity of 1,6-hexanediamine dihydrochloride in F344/N rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;20(3):348-59.
1993: J Yuan; M P Dieter; John R Bucher; C W Jameson
Application of microencapsulation for toxicology studies. III. Bioavailability of microencapsulated cinnamaldehyde.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;20(1):83-7.
1992: J H Yuan; M P Dieter; John R Bucher; C W Jameson
Toxicokinetics of cinnamaldehyde in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(12):997-1004.
1992: J Yuan; John R Bucher; TJ Goehl; M P Dieter; C W Jameson
Quantitation of cinnamaldehyde and cinnamic acid in blood by HPLC.
Journal of analytical toxicology 1992;16(6):359-62.
1991: John R Bucher; milton hejtmancik; J D Toft; R L Persing; S L Eustis; J K Haseman
Results and conclusions of the National Toxicology Program's rodent carcinogenicity studies with sodium fluoride.
International journal of cancer. Journal international du cancer 1991;48(5):733-7.
1991: R E Morrissey; S Eustis; J K Haseman; James Huff; John R Bucher
Toxicity and carcinogenicity studies of nalidixic acid in rodents.
Drug and chemical toxicology 1991;14(1-2):45-66.
1990: D L Morgan; John R Bucher; Michael R Elwell; H S Lilja; A S Murthy
Comparative toxicity of ethylene dichloride in F344/N, Sprague-Dawley and Osborne-Mendel rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1990;28(12):839-45.
1990: John R Bucher; J Huff; J K Haseman; S L Eustis; A Peters; J D Toft
Neurotoxicity and carcinogenicity of N-methylolacrylamide in F344 rats and B6C3F1 mice.
Journal of toxicology and environmental health 1990;31(3):161-77.
1990: John R Bucher; James Huff; J K Haseman; S L Eustis; W E Davis; E F Meierhenry
Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 2. Furosemide.
Journal of applied toxicology : JAT 1990;10(5):369-78.
1990: John R Bucher; James Huff; J K Haseman; S L Eustis; Michael R Elwell; W E Davis; E F Meierhenry
Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 1. Hydrochlorothiazide.
Journal of applied toxicology : JAT 1990;10(5):359-67.
1990: John R Bucher; James Huff; J K Haseman; S L Eustis; H S Lilja; A S Murthy
No evidence of toxicity or carcinogenicity of pentaerythritol tetranitrate given in the diet to F344 rats and B6C3F1 mice for up to two years.
Journal of applied toxicology : JAT 1990;10(5):353-7.
1990: John R Bucher; Michael R Elwell; M B Thompson; Billy J Chou; R Renne; H A Ragan
Inhalation toxicity studies of cobalt sulfate in F344/N rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(2):357-72.
1988: John R Bucher; James Huff; J K Haseman
Toxicity and carcinogenicity studies of phenylephrine hydrochloride in F344/N rats and B6C3F1 mice.
Drug and chemical toxicology 1988;11(4):355-70.
1987: K Mitsumori; Gary A Boorman; B N Gupta; John R Bucher
Four-day repeated inhalation and recovery study of methyl isocyanate in F344 rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1987;9(3):480-95.
1987: John R Bucher; R H Alison; Charles Montgomery; James Huff; J K Haseman; D Farnell; R Thompson; J D Prejean
Comparative toxicity and carcinogenicity of two chlorinated paraffins in F344/N rats and B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1987;9(3):454-68.
1987: John R Bucher
Methyl isocyanate: a review of health effects research since Bhopal.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1987;9(3):367-79.