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Marilia Cascalho

Research Profile

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TOP 3
Marilia I Cascalho; Brian J Chen; Mandy Kain; Jeffrey L Platt
The paradoxical functions of B cells and antibodies in transplantation.
Mouhammed AbuAttieh; Diane Bender; Esther Liu; Jeffrey L Platt; Peter Wettstein; Marilia I Cascalho
Affinity maturation of antibodies requires integrity of the adult thymus.
Shoichiro Tsuji; Richard J Bram; Catarina Cortesao; Jeffrey L Platt; Marilia I Cascalho
TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow.

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All Publications

2013: Marilia I Cascalho; Brian J Chen; Mandy Kain; Jeffrey L Platt
The paradoxical functions of B cells and antibodies in transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(3):875-9.
2012: Mouhammed AbuAttieh; Diane Bender; Esther Liu; Jeffrey L Platt; Peter Wettstein; Marilia I Cascalho
Affinity maturation of antibodies requires integrity of the adult thymus.
European journal of immunology 2012;42(2):500-10.
2011: Shoichiro Tsuji; Richard J Bram; Catarina Cortesao; Jeffrey L Platt; Marilia I Cascalho
TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow.
Blood 2011;118(22):5832-9.
2011: Jeffrey L Platt; Marilia I Cascalho
Donor specific antibodies after transplantation.
Pediatric transplantation 2011;15(7):686-90.
2010: Anna Bolduc; Eugene Long; Dale Stapler; Marilia I Cascalho; Takeshi Tsubata; Pandelakis Koni; Michiko Shimoda
Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):220-30.
2010: Samuel J Balin; Marilia I Cascalho
The rate of mutation of a single gene.
Nucleic acids research 2010;38(5):1575-82.
2009: Jeffrey L Platt; Marilia I Cascalho; Lori West
Lessons from cardiac transplantation in infancy.
Pediatric transplantation 2009;13(7):814-9.
2009: Samuel J Balin; Jeffrey L Platt; Marilia I Cascalho
Noncognate function of B cells in transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(6):593-8.
2008: Samuel J Balin; Jeffrey L Platt; Marilia I Cascalho
New insights into the functions of B cells.
Pediatric transplantation 2008;12(5):510-5.
2008: Samuel J Balin; Ted M Ross; Jeffrey L Platt; Marilia I Cascalho
HIV genes diversify in B cells.
Current HIV research 2008;6(1):10-8.
2007: Denise A Martin; Liwei Lu; Marilia I Cascalho; Gillian E Wu
Maintenance of surrogate light chain expression induces developmental delay in early B cell compartment.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):4996-5005.
2007: George T Mantchev; Catarina Cortesao; Michelle Rebrovich; Marilia I Cascalho; Richard J Bram
TACI is required for efficient plasma cell differentiation in response to T-independent type 2 antigens.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2282-8.
2007: Pedro Geraldes; Michelle Rebrovich; Kai Herrmann; Jamie Wong; Hans-Martin Jäck; Matthias Wabl; Marilia I Cascalho
Ig heavy chain promotes mature B cell survival in the absence of light chain.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1659-68.
2007: Amy H Tang; Gregory J Brunn; Marilia I Cascalho; Jeffrey L Platt
Pivotal advance: endogenous pathway to SIRS, sepsis, and related conditions.
Journal of leukocyte biology 2007;82(2):282-5.
2007: Allan D Kirk; William M Baldwin; Marilia I Cascalho; A S Chong; M Sykes; L J West
American society of transplantation symposium on B cells in transplantation: harnessing humoral immunity from rodent models to clinical practice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(6):1464-70.
2007: K Solez; Robert Colvin; Lorraine C Racusen; B Sis; P F Halloran; P E Birk; P M Campbell; Marilia I Cascalho; A B Collins; Anthony Demetris; Cinthia Drachenberg; I W Gibson; P C Grimm; Mark Haas; E Lerut; H Liapis; R B Mannon; P B Marcus; M Mengel; M J Mihatsch; B J Nankivell; Volker Nickeleit; John C Papadimitriou; Jeffrey L Platt; P Randhawa; I Roberts; L Salinas-Madriga; D R Salomon; D Seron; M Sheaff; J J Weening
Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN').
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(3):518-26.
2007: Mouhammed AbuAttieh; Michelle Rebrovich; Peter J Wettstein; Zvezdana Vuk-Pavlovic; Andrew H Limper; Jeffrey L Platt; Marilia I Cascalho
Fitness of cell-mediated immunity independent of repertoire diversity.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2950-60.
2007: Marilia I Cascalho; Jeffrey L Platt
Novel functions of B cells.
Critical reviews in immunology 2007;27(2):141-51.
2006: Marilia I Cascalho; Jeffrey L Platt
The future of organ replacement: needs, potential applications, and obstacles to application.
Transplantation proceedings 2006;38(2):362-4.
2006: Brenda M Ogle; Lori J West; David J Driscoll; Scott E Strome; Raymund R Razonable; Carlos V Paya; Marilia I Cascalho; Jeffrey L Platt
Effacing of the T cell compartment by cardiac transplantation in infancy.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1962-7.
2006: Marilia I Cascalho; Brenda M Ogle; Jeffrey L Platt
The future of organ transplantation.
Annals of transplantation : quarterly of the Polish Transplantation Society 2006;11(2):44-7.
2005: Brenda M Ogle; Marilia I Cascalho; Jeffrey L Platt
Biological implications of cell fusion.
Nature reviews. Molecular cell biology 2005;6(7):567-75.
2005: Marilia I Cascalho
B cell tolerance: lessons from transplantation.
Current drug targets. Cardiovascular & haematological disorders 2005;5(3):271-5.
2005: Marilia I Cascalho; Brenda M Ogle; Jeffrey L Platt
Xenotransplantation and the future of renal replacement.
The Journal of urology 2005;173(4):1431.
2005: Marilia I Cascalho; Jeffrey L Platt
New technologies for organ replacement and augmentation.
Mayo Clinic proceedings. Mayo Clinic 2005;80(3):370-8.
2005: Marilia I Cascalho; Jeffrey L Platt
Basic mechanisms of humoral rejection.
Pediatric transplantation 2005;9(1):9-16.
2005: Naoki Kanayama; Marilia I Cascalho; Hitoshi Ohmori
Analysis of marginal zone B cell development in the mouse with limited B cell diversity: role of the antigen receptor signals in the recruitment of B cells to the marginal zone.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1438-45.
2005: Xiaosheng Wu; Pedro Geraldes; Jeffrey L Platt; Marilia I Cascalho
The double-edged sword of activation-induced cytidine deaminase.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):934-41.
2004: Marilia I Cascalho; Brenda M Ogle; Jeffrey L Platt
New approaches to replacing failing organs.
Transplantation proceedings 2004;36(6):1629.
2004: Marilia I Cascalho
Advantages and disadvantages of cytidine deamination.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6513-8.
2004: Irene M Ward; Bernardo Reina-San-Martin; Andreea Olaru; Kay Minn; Koji Tamada; Julie S Lau; Marilia I Cascalho; Lieping Chen; André Nussenzweig; Ferenc Livak; Michel C Nussenzweig; Junjie Chen
53BP1 is required for class switch recombination.
The Journal of cell biology 2004;165(4):459-64.
2004: Marilia I Cascalho; Jeffrey L Platt
B cell-dependent T cell development.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2004;93(445):52-3; discussion 54.
2004: Marilia I Cascalho; Brenda M Ogle; Jeffrey L Platt
Xenotransplantation and the future of renal replacement.
Journal of the American Society of Nephrology : JASN 2004;15(5):1106-12.
2004: Cristina João; Brenda M Ogle; Carlota Gay-Rabinstein; Jeffrey L Platt; Marilia I Cascalho
B cell-dependent TCR diversification.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4709-16.
2004: Brenda M Ogle; Kim A Butters; Timothy B Plummer; Kevin R Ring; Bruce E Knudsen; Mark R Litzow; Marilia I Cascalho; Jeffrey L Platt
Spontaneous fusion of cells between species yields transdifferentiation and retroviral transfer in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(3):548-50.
2004: X Wu; Z Khalpey; Marilia I Cascalho
Cellular physiology of mismatch repair.
Current pharmaceutical design 2004;10(32):4121-6.
2004: Hidefumi Kojima; Brendan T Jones; Jianzhu Chen; Marilia I Cascalho; Michail V Sitkovsky
Hypoxia-inducible factor 1alpha-deficient chimeric mice as a model to study abnormal B lymphocyte development and autoimmunity.
Methods in enzymology 2004;381():218-29.
2004: Brenda Ogle; Marilia I Cascalho; Jeffrey L Platt
Fusion of approaches to the treatment of organ failure.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4 Suppl 6():74-7.
2003: Brenda M Ogle; Marilia I Cascalho; Cristina Joao; William Taylor; Lori J West; Jeffrey L Platt
Direct measurement of lymphocyte receptor diversity.
Nucleic acids research 2003;31(22):e139.
2003: S Keshavarzi; C Rietz; S Simões; S Shih; Jeffrey L Platt; J Wong; Matthias Wabl; Marilia I Cascalho
The possibility of B-cell-dependent T-cell development.
Scandinavian journal of immunology 2003;57(5):446-52.
2003: Xiaosheng Wu; Jeffrey L Platt; Marilia I Cascalho
Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha.
Molecular and cellular biology 2003;23(9):3320-8.
2003: Hidefumi Kojima; Michail V Sitkovsky; Marilia I Cascalho
HIF-1 alpha deficiency perturbs T and B cell functions.
Current pharmaceutical design 2003;9(23):1827-32.
2002: Naoki Kanayama; Takafumi Kimoto; Kagefumi Todo; Yumiko Nishikawa; Masaki Hikida; Masaki Magari; Marilia I Cascalho; Hitoshi Ohmori
B cell selection and affinity maturation during an antibody response in the mouse with limited B cell diversity.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):6865-74.
2002: Masaki Magari; Takashi Sawatari; Yohei Kawano; Marilia I Cascalho; Matthias Wabl; Naoki Kanayama; Masaki Hikida; Hitoshi Ohmori
Contribution of light chain rearrangement in peripheral B cells to the generation of high-affinity antibodies.
European journal of immunology 2002;32(4):957-66.
2002: Brian P O'Connor; Marilia I Cascalho; Randolph J Noelle
Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population.
The Journal of experimental medicine 2002;195(6):737-45.
2002: Loren D Erickson; Brigit G Durell; Laura Vogel; Brian P O'Connor; Marilia I Cascalho; Teruhito Yasui; Hitoshi Kikutani; Randolph J Noelle
Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.
The Journal of clinical investigation 2002;109(5):613-20.
2001: Marilia I Cascalho; Jeffrey L Platt
Xenotransplantation and other means of organ replacement.
Nature reviews. Immunology 2001;1(2):154-60.
2001: Marilia I Cascalho; Jeffrey L Platt
The immunological barrier to xenotransplantation.
Immunity 2001;14(4):437-46.
2001: Rachel Golub; D Martin; FE Bertrand; Marilia I Cascalho; Matthias Wabl; Gillian E Wu
VH gene replacement in thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):855-60.
2000: Loren D Erickson; Laura Vogel; Marilia I Cascalho; J Wong; Matthias Wabl; Brigit G Durell; Randolph J Noelle
B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell-independent immune responses in an Ig transgenic system.
European journal of immunology 2000;30(11):3121-31.
2000: C G de Vinuesa; Matthew C Cook; Jennifer Ball; M Drew; Y Sunners; Marilia I Cascalho; Matthias Wabl; Gerry G B Klaus; Ian C M MacLennan
Germinal centers without T cells.
The Journal of experimental medicine 2000;191(3):485-94.
2000: Marilia I Cascalho; J Wong; J Brown; Hans-Martin Jäck; C Steinberg; Matthias Wabl
A B220(-), CD19(-) population of B cells in the peripheral blood of quasimonoclonal mice.
International immunology 2000;12(1):29-35.
1999: C García de Vinuesa; Adam Gulbranson-Judge; Mahmood Khan; P O'Leary; Marilia I Cascalho; Matthias Wabl; Gerry G B Klaus; M J Owen; Ian C M MacLennan
Dendritic cells associated with plasmablast survival.
European journal of immunology 1999;29(11):3712-21.
1999: Constantino López-Macías; Ulrich Kalinke; Marilia I Cascalho; Matthias Wabl; Hans Hengartner; Rolf M Zinkernagel; Alain Lamarre
Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses.
The Journal of experimental medicine 1999;189(11):1791-8.
1999: Matthias Wabl; Marilia I Cascalho; C Steinberg
Hypermutation in antibody affinity maturation.
Current opinion in immunology 1999;11(2):186-9.
1999: Marilia I Cascalho; Denise A Martin; J Wong; Queenie Lai Kwan Lam; Matthias Wabl; Gillian E Wu
A mouse with a monoclonal primary immunoglobulin repertoire not further diversified by V-gene replacement.
Developmental immunology 1999;7(1):43-50.
1998: Marilia I Cascalho; J Wong; C Steinberg; Matthias Wabl
Mismatch repair co-opted by hypermutation.
Science (New York, N.Y.) 1998;279(5354):1207-10.
1997: Marilia I Cascalho; J Wong; Matthias Wabl
VH gene replacement in hyperselected B cells of the quasimonoclonal mouse.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5795-801.
1996: L Masat; Marilia I Cascalho; Matthias Wabl
Loss of the beta 1 subunit of the sodium pump during lymphocyte differentiation.
European journal of immunology 1996;26(11):2731-5.
1996: Marilia I Cascalho; A Ma; S Lee; L Masat; Matthias Wabl
A quasi-monoclonal mouse.
Science (New York, N.Y.) 1996;272(5268):1649-52.
1990: Steinunn Baekkeskov; Henk-Jan Aanstoot; Stephan Christgau; A Reetz; Michele Solimena; Marilia I Cascalho; Franco Folli; H Richter-Olesen; Pietro De Camilli; P D Camilli
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
Nature 1990;347(6289):151-6.
1988: L M Falcão; J G Clara; Marilia I Cascalho; D Matias; E Mota
[Septal rupture after acute myocardial infarct].
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 1988;7(4):431-7.