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Manfred Frasch
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Research Profile (preview)
Chemicals & Drugs
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Physiology
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Network (preview)
9
Lo, Patrick
9
Zaffran, Stéphane
7
Saumweber, Harald
5
Reim, Ingolf
5
Levine, Michael
4
Lee, Hsiu-Hsiang
3
Lufkin, Thomas
3
Yin, Z
2
Nguyen, Hanh
2
Bellard, M
2
Gajewski, Kathleen
2
Glover, David
2
Jagla, Krzysztof
2
Paterson, Bruce
1
Ronshaugen, Matthew
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All Publications
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2008: Frasch Manfred
A matter of timing: microRNA-controlled temporal identities in worms and flies.
Genes & development 2008;22(12):1572-6.
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2007: Lo Patrick C H; Zaffran Stéphane; Sénatore Sébastien; Frasch Manfred
The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis.
Developmental biology 2007;311(2):287-96.
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2007: Nguyen Hanh T; Voza Francesca; Ezzeddine Nader; Frasch Manfred
Drosophila mind bomb2 is required for maintaining muscle integrity and survival.
The Journal of cell biology 2007;179(2):219-27.
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2007: Goltsev Yury; Fuse Naoyuki; Frasch Manfred; Zinzen Robert P; Lanzaro Gregory; Levine Mike
Evolution of the dorsal-ventral patterning network in the mosquito, Anopheles gambiae.
Development (Cambridge, England) 2007;134(13):2415-24.
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2006: Zaffran Stéphane; Reim Ingolf; Qian Li; Lo Patrick C; Bodmer Rolf; Frasch Manfred
Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila.
Development (Cambridge, England) 2006;133(20):4073-83.
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2006: Nguyen Hanh T; Frasch Manfred
MicroRNAs in muscle differentiation: lessons from Drosophila and beyond.
Current opinion in genetics & development 2006;16(5):533-9.
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2005: Reim Ingolf; Frasch Manfred
The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila.
Development (Cambridge, England) 2005;132(22):4911-25.
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2005: Reim Ingolf; Mohler James P; Frasch Manfred
Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila.
Mechanisms of development 2005;122(9):1056-69.
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2005: Zaffran Stéphane; Frasch Manfred
The homeodomain of Tinman mediates homo- and heterodimerization of NK proteins.
Biochemical and biophysical research communications 2005;334(2):361-9.
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2005: Wang Jianbo; Tao Ye; Reim Ingolf; Gajewski Kathleen; Frasch Manfred; Schulz Robert A
Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster.
Molecular and cellular biology 2005;25(10):4200-10.
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2005: Lee Hsiu-Hsiang; Frasch Manfred
Nuclear integration of positive Dpp signals, antagonistic Wg inputs and mesodermal competence factors during Drosophila visceral mesoderm induction.
Development (Cambridge, England) 2005;132(6):1429-42.
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2004: Stathopoulos Angelike; Tam Bergin; Ronshaugen Matthew; Frasch Manfred; Levine Michael
pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos.
Genes & development 2004;18(6):687-99.
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2004: Lee Hsiu-Hsiang; Frasch Manfred
Survey of forkhead domain encoding genes in the Drosophila genome: Classification and embryonic expression patterns.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;229(2):357-66.
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2003: Lee Hsiu-Hsiang; Norris Audra; Weiss Joseph B; Frasch Manfred
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers.
Nature 2003;425(6957):507-12.
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2003: Lo Patrick C H; Frasch Manfred
Establishing A-P polarity in the embryonic heart tube: a conserved function of Hox genes in Drosophila and vertebrates?
Trends in cardiovascular medicine 2003;13(5):182-7.
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2003: Reim Ingolf; Lee Hsiu-Hsiang; Frasch Manfred
The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp.
Development (Cambridge, England) 2003;130(14):3187-204.
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2002: Lo Patrick C H; Skeath James B; Gajewski Kathleen; Schulz Robert A; Frasch Manfred
Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heart.
Developmental biology 2002;251(2):307-19.
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2002: Zaffran Stéphane; Frasch Manfred
Early signals in cardiac development.
Circulation research 2002;91(6):457-69.
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2002: Zaffran Stephane; Frasch Manfred
The beta 3 tubulin gene is a direct target of bagpipe and biniou in the visceral mesoderm of Drosophila.
Mechanisms of development 2002;114(1-2):85-93.
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2002: Zaffran S; Xu X; Lo P C; Lee H H; Frasch M
Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors.
Cold Spring Harbor symposia on quantitative biology 2002;67():1-12.
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2001: Zaffran S; Küchler A; Lee H H; Frasch M
biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila.
Genes & development 2001;15(21):2900-15.
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2001: Knirr S; Frasch M
Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors.
Developmental biology 2001;238(1):13-26.
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2001: Lo P C; Frasch M
A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila.
Mechanisms of development 2001;104(1-2):49-60.
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2001: Jagla K; Bellard M; Frasch M
A cluster of Drosophila homeobox genes involved in mesoderm differentiation programs.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(2):125-33.
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2000: Wang W; Lo P; Frasch M; Lufkin T
Hmx: an evolutionary conserved homeobox gene family expressed in the developing nervous system in mice and Drosophila.
Mechanisms of development 2000;99(1-2):123-37.
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2000: Lee H H; Frasch M
Wingless effects mesoderm patterning and ectoderm segmentation events via induction of its downstream target sloppy paired.
Development (Cambridge, England) 2000;127(24):5497-508.
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2000: Read D; Butte M J; Dernburg A F; Frasch M; Kornberg T B
Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins.
Nucleic acids research 2000;28(20):3864-70.
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2000: Frasch M; Leptin M
Mergers and acquisitions: unequal partnerships in Drosophila myoblast fusion.
Cell 2000;102(2):127-9.
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2000: Zaffran S; Das G; Frasch M
The NK-2 homeobox gene scarecrow (scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos.
Mechanisms of development 2000;94(1-2):237-41.
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2000: Zaffran S; Frasch M
Barbu: an E(spl) m4/m(alpha)-related gene that antagonizes Notch signaling and is required for the establishment of ommatidial polarity.
Development (Cambridge, England) 2000;127(5):1115-30.
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1999: Frasch M
Controls in patterning and diversification of somatic muscles during Drosophila embryogenesis.
Current opinion in genetics & development 1999;9(5):522-9.
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1999: Knirr S; Azpiazu N; Frasch M
The role of the NK-homeobox gene slouch (S59) in somatic muscle patterning.
Development (Cambridge, England) 1999;126(20):4525-35.
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1999: Lo P C; Frasch M
Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-beta superfamily.
Mechanisms of development 1999;86(1-2):171-5.
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1999: Frasch M
Intersecting signalling and transcriptional pathways in Drosophila heart specification.
Seminars in cell & developmental biology 1999;10(1):61-71.
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1998: Xu X; Yin Z; Hudson J B; Ferguson E L; Frasch M
Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm.
Genes & development 1998;12(15):2354-70.
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1998: Lo P C; Frasch M
bagpipe-Dependent expression of vimar, a novel Armadillo-repeats gene, in Drosophila visceral mesoderm.
Mechanisms of development 1998;72(1-2):65-75.
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1998: Yin Z; Frasch M
Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila.
Developmental genetics 1998;22(3):187-200.
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1997: Yin Z; Xu X L; Frasch M
Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development.
Development (Cambridge, England) 1997;124(24):4971-82.
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1997: Lo P C; Frasch M
A novel KH-domain protein mediates cell adhesion processes in Drosophila.
Developmental biology 1997;190(2):241-56.
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1997: Jagla K; Frasch M; Jagla T; Dretzen G; Bellard F; Bellard M
ladybird, a new component of the cardiogenic pathway in Drosophila required for diversification of heart precursors.
Development (Cambridge, England) 1997;124(18):3471-9.
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1997: Tribioli C; Frasch M; Lufkin T
Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton.
Mechanisms of development 1997;65(1-2):145-62.
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1996: Azpiazu N; Lawrence P A; Vincent J P; Frasch M
Segmentation and specification of the Drosophila mesoderm.
Genes & development 1996;10(24):3183-94.
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1996: D'Alessio M; Frasch M
msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm.
Mechanisms of development 1996;58(1-2):217-31.
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1995: Küssel P; Frasch M
Yeast Srp1, a nuclear protein related to Drosophila and mouse pendulin, is required for normal migration, division, and integrity of nuclei during mitosis.
Molecular & general genetics : MGG 1995;248(3):351-63.
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1995: Maggert K; Levine M; Frasch M
The somatic-visceral subdivision of the embryonic mesoderm is initiated by dorsal gradient thresholds in Drosophila.
Development (Cambridge, England) 1995;121(7):2107-16.
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1995: Fernandez R; Tabarini D; Azpiazu N; Frasch M; Schlessinger J
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.
The EMBO journal 1995;14(14):3373-84.
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1995: Küssel P; Frasch M
Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation.
The Journal of cell biology 1995;129(6):1491-507.
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1995: Frasch M; Chen X; Lufkin T
Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila.
Development (Cambridge, England) 1995;121(4):957-74.
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1995: Frasch M
Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo.
Nature 1995;374(6521):464-7.
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1993: Azpiazu N; Frasch M
tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila.
Genes & development 1993;7(7B):1325-40.
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1993: Bate M; Rushton E; Frasch M
A dual requirement for neurogenic genes in Drosophila myogenesis.
Development (Cambridge, England). Supplement 1993;():149-61.
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1992: Paterson B M; Shirakata M; Nakamura S; Dechesne C; Walldorf U; Eldridge J; Dübendorfer A; Frasch M; Gehring W J
Isolation and functional comparison of Dmyd, the Drosophila homologue of the vertebrate myogenic determination genes, with CMD1.
Symposia of the Society for Experimental Biology 1992;46():89-109.
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1991: van Lohuizen M; Frasch M; Wientjens E; Berns A
Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2.
Nature 1991;353(6342):353-5.
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1991: Champlin D T; Frasch M; Saumweber H; Lis J T
Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin.
Genes & development 1991;5(9):1611-21.
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1991: Ohtsubo M; Yoshida T; Seino H; Nishitani H; Clark K L; Sprague G F; Frasch M; Nishimoto T
Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae.
The EMBO journal 1991;10(5):1265-73.
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1991: Frasch M
The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.
The EMBO journal 1991;10(5):1225-36.
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1991: Paterson B M; Walldorf U; Eldridge J; Dübendorfer A; Frasch M; Gehring W J
The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3782-6.
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1990: Dohrmann C; Azpiazu N; Frasch M
A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis.
Genes & development 1990;4(12A):2098-111.
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1990: Saumweber H; Frasch M; Korge G
Two puff-specific proteins bind within the 2.5 kb upstream region of the Drosophila melanogaster Sgs-4 gene.
Chromosoma 1990;99(1):52-60.
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1989: Frasch M; Saumweber H
Two proteins from Drosophila nuclei are bound to chromatin and are detected in a series of puffs on polytene chromosomes.
Chromosoma 1989;97(4):272-81.
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1988: Frasch M; Warrior R; Tugwood J; Levine M
Molecular analysis of even-skipped mutants in Drosophila development.
Genes & development 1988;2(12B):1824-38.
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1988: Frasch M; Paddy M; Saumweber H
Developmental and mitotic behaviour of two novel groups of nuclear envelope antigens of Drosophila melanogaster.
Journal of cell science 1988;90 ( Pt 2)():247-63.
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1988: Whitfield W G; Millar S E; Saumweber H; Frasch M; Glover D M
Cloning of a gene encoding an antigen associated with the centrosome in Drosophila.
Journal of cell science 1988;89 ( Pt 4)():467-80.
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1988: Ruder F J; Frasch M; Büsen W
Specific radioimmunoprecipitation of histone H2A antigens by protein A conjugated sepharose.
Experientia 1988;44(4):347-8.
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1987: Rushlow C; Frasch M; Doyle H; Levine M
Maternal regulation of zerknüllt: a homoeobox gene controlling differentiation of dorsal tissues in Drosophila.
Nature 1987;330(6148):583-6.
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1987: Frasch M; Levine M
Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila.
Genes & development 1987;1(9):981-95.
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1987: Frasch M; Hoey T; Rushlow C; Doyle H; Levine M
Characterization and localization of the even-skipped protein of Drosophila.
The EMBO journal 1987;6(3):749-59.
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1986: Frasch M; Glover D M; Saumweber H
Nuclear antigens follow different pathways into daughter nuclei during mitosis in early Drosophila embryos.
Journal of cell science 1986;82():155-72.
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1983: Risau W; Symmons P; Saumweber H; Frasch M
Nonpackaging and packaging proteins of hnRNA in Drosophila melanogaster.
Cell 1983;33(2):529-41.
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