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Sebastian Springer

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Publications

TOP 3
Susanne Fritzsche; Sebastian Springer
Investigating MHC class I folding and trafficking with pulse-chase experiments.
Sunil Kumar Saini; Esam Tolba Abualrous; Kathryn Covella; Anca-Sarmiza Tigan; Ursula Wellbrock; Sebastian Springer
Not all empty MHC class I molecules are molten globules: tryptophan fluorescence reveals a two-step mechanism of thermal denaturation.
Esther Ghanem; Sebastian Springer
Determining the activity of the transporter associated with antigen processing in the compartments of the secretory pathway.

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All Publications

2013: Susanne Fritzsche; Sebastian Springer
Investigating MHC class I folding and trafficking with pulse-chase experiments.
Molecular immunology 2013;55(2):126-30.
2013: Sunil Kumar Saini; Esam Tolba Abualrous; Kathryn Covella; Anca-Sarmiza Tigan; Ursula Wellbrock; Sebastian Springer
Not all empty MHC class I molecules are molten globules: tryptophan fluorescence reveals a two-step mechanism of thermal denaturation.
Molecular immunology 2013;54(3-4):386-96.
2013: Esther Ghanem; Sebastian Springer
Determining the activity of the transporter associated with antigen processing in the compartments of the secretory pathway.
Methods in molecular biology (Clifton, N.J.) 2013;960():137-44.
2011: Malgorzata Anna Garstka; Zeynep Hein; Gytis Jankevicius; Izabela Lenart; Antony N Antoniou; Louise H Boyle; Tim Elliott; Susanne Fritzsche; John Trowsdale; Martin Zacharias; Sebastian Springer
Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(11):3989-98.
2010: Esther Ghanem; Susanne Fritzsche; Mohammed Al-Balushi; Jood Hashem; Lana Ghuneim; Lena Thomer; Hubert Kalbacher; Peter van Endert; Emmanuel Wiertz; Robert Tampé; Sebastian Springer
The transporter associated with antigen processing (TAP) is active in a post-ER compartment.
Journal of cell science 2010;123(Pt 24):4271-9.
2010: Deborah Studer; Raghavendra Palankar; Matthieu Bédard; Mathias Winterhalter; Sebastian Springer
Retrieval of a metabolite from cells with polyelectrolyte microcapsules.
Small (Weinheim an der Bergstrasse, Germany) 2010;6(21):2412-9.
2010: Praveen Pudiavettil Tayakuniyil; Rakina Yaneva; Hubert Kalbacher; Sebastian Springer
Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange.
European journal of immunology 2010;40(1):214-24.
2010: Rakina Yaneva; Clemens Schneeweiss; Martin Zacharias; Sebastian Springer
Peptide binding to MHC class I and II proteins: new avenues from new methods.
Molecular immunology 2010;47(4):649-57.
2009: Raghavendra Palankar; André G Skirtach; Oliver Kreft; Matthieu Bédard; Malgorzata Garstka; Keith Gould; Helmuth Möhwald; Gleb B Sukhorukov; Matthias Winterhalter; Sebastian Springer
Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules.
Small (Weinheim an der Bergstrasse, Germany) 2009;5(19):2168-76.
2009: Clemens Schneeweiss; Malgorzata Garstka; James Smith; Marc-Thorsten Hütt; Sebastian Springer
The mechanism of action of tapasin in the peptide exchange on MHC class I molecules determined from kinetics simulation studies.
Molecular immunology 2009;46(10):2054-63.
2009: Rakina Yaneva; Sebastian Springer; Martin Zacharias
Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study.
Biopolymers 2009;91(1):14-27.
2008: Florian Sieker; Tjerk P Straatsma; Sebastian Springer; Martin Zacharias
Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: a molecular dynamics simulation study.
Molecular immunology 2008;45(14):3714-22.
2007: Malgorzata Garstka; Britta Borchert; Mohammed Al-Balushi; Praveen Pudiavettil Tayakuniyil; Nicole Kühl; Irina Majoul; Rainer Dr. Duden; Sebastian Springer
Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes.
The Journal of biological chemistry 2007;282(42):30680-90.
2007: Gleb B Sukhorukov; Andrey L Rogach; Malgorzata Garstka; Sebastian Springer; Wolfgang J Parak; Almudena Muñoz Javier; Oliver Kreft; Andre G Skirtach; Andrei S Susha; Yannic Ramaye; Raghavendra Palankar; Mathias Winterhalter
Multifunctionalized polymer microcapsules: novel tools for biological and pharmacological applications.
Small (Weinheim an der Bergstrasse, Germany) 2007;3(6):944-55.
2007: Florian Sieker; Sebastian Springer; Martin Zacharias
Comparative molecular dynamics analysis of tapasin-dependent and -independent MHC class I alleles.
Protein science : a publication of the Protein Society 2007;16(2):299-308.
2004: Martin Zacharias; Sebastian Springer
Conformational flexibility of the MHC class I alpha1-alpha2 domain in peptide bound and free states: a molecular dynamics simulation study.
Biophysical journal 2004;87(4):2203-14.
2004: Cynthia Anne Wright; Patrycja Kozik; Martin Zacharias; Sebastian Springer
Tapasin and other chaperones: models of the MHC class I loading complex.
Biological chemistry 2004;385(9):763-78.
2001: G Z Lederkremer; Yuan Cheng; Benjamin M Petre; E Vogan; Sebastian Springer; Randy Schekman; Thomas Walz; Tomas Kirchhausen
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10704-9.
2000: Sebastian Springer; E Chen; Rainer Dr. Duden; M Marzioch; A Rowley; Susan Hamamoto; S Merchant; Randy Schekman
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4034-9.
1999: Sebastian Springer; Anne Spang; Randy Schekman
A primer on vesicle budding.
Cell 1999;97(2):145-8.
1999: Ann Glithero; Jose Tormo; JS Haurum; Gemma Arsequell; Gregorio Valencia; J Edwards; Sebastian Springer; A Townsend; Y L Pao; Mark R Wormald; Raymond A Dwek; E Yvonne Jones; Tim Elliott
Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Immunity 1999;10(1):63-74.
1998: Sebastian Springer; Randy Schekman
Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs.
Science (New York, N.Y.) 1998;281(5377):698-700.
1998: Sebastian Springer; K Doring; J C Skipper; A R Townsend; V Cerundolo
Fast association rates suggest a conformational change in the MHC class I molecule H-2Db upon peptide binding.
Biochemistry 1998;37(9):3001-12.