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Hechmi Louzir

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Noureddine Ben Khalaf; Géraldine De Muylder; Hechmi Louzir; James McKerrow; Mehdi Chenik
Leishmania major protein disulfide isomerase as a drug target: enzymatic and functional characterization.
Nadia Belhadj Hmida; Nadia Kourda; Hechmi Louzir; Bertrand Meresse; Amel Moussa; Majd Ben Rejeb; Yosra Said; Maha Abdeladhim; Mélika Ben Ahmed; Nadine Cerf-Bensussan
Impaired control of effector T cells by regulatory T cells: a clue to loss of oral tolerance and autoimmunity in celiac disease?
Asma El Beldi; Mourad Mokni; Amel Ben Osman; Inès Zaraa; Mélika B Ahmed; Hechmi Louzir
Prevalence of autoantibodies in patients with pemphigus.

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All Publications

2012: Noureddine Ben Khalaf; Géraldine De Muylder; Hechmi Louzir; James McKerrow; Mehdi Chenik
Leishmania major protein disulfide isomerase as a drug target: enzymatic and functional characterization.
Parasitology research 2012;110(5):1911-7.
2012: Nadia Belhadj Hmida; Nadia Kourda; Hechmi Louzir; Bertrand Meresse; Amel Moussa; Majd Ben Rejeb; Yosra Said; Maha Abdeladhim; Mélika Ben Ahmed; Nadine Cerf-Bensussan
Impaired control of effector T cells by regulatory T cells: a clue to loss of oral tolerance and autoimmunity in celiac disease?
The American journal of gastroenterology 2012;107(4):604-11.
2012: Asma El Beldi; Mourad Mokni; Amel Ben Osman; Inès Zaraa; Mélika B Ahmed; Hechmi Louzir
Prevalence of autoantibodies in patients with pemphigus.
Indian journal of dermatology, venereology and leprology 2012;78(2):192-3.
2012: Soumaya Marzouki; Fabiano Oliveira; Jesus G Valenzuela; Maha Abdeladhim; Chaouki Ben Abdessalem; Beya Ferjani; Dana Gilmore; Hechmi Louzir; Mélika Ben Ahmed
Salivary antigen SP32 is the immunodominant target of the antibody response to Phlebotomus papatasi bites in humans.
PLoS neglected tropical diseases 2012;6(11):e1911.
2012: Maha Abdeladhim; Mélika Ben Ahmed; Ifhem Chelbi; Saifedine Cherni; Ryan Jochim; Hechmi Louzir; José M C Ribeiro; Elyes Zhioua; Jesus G Valenzuela
Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans.
PloS one 2012;7(11):e47347.
2011: Maha Abdeladhim; Nadia Belhadj Hmida; Nabil Belhaj Hamida; Mélika Ben Ahmed; Afif Ben Salah; Thouraya Boussoffara; Soumaya Marzouki; Hechmi Louzir
Human cellular immune response to the saliva of Phlebotomus papatasi is mediated by IL-10-producing CD8+ T cells and Th1-polarized CD4+ lymphocytes.
PLoS neglected tropical diseases 2011;5(10):e1345.
2011: Asma Elbeldi-Ferchiou; Mohamed Habib Houman; Monia Smiti Khanfir; Maha Abdeladhim; Nadia Belhadj Hmida; Mélika Ben Ahmed; Nadine Cerf-Bensussan; Hechmi Louzir
Resistance to exogenous TGF-β effects in patients with systemic lupus erythematosus.
Journal of clinical immunology 2011;31(4):574-83.
2011: Soumaya Marzouki; Mélika Ben Ahmed; Thouraya Boussoffara; Maha Abdeladhim; Abdelkader Namane; Nabil Belhaj Hamida; Nissaf Ben Aleya-Bouafif; Afif Ben Salah; Hechmi Louzir
Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis.
The American journal of tropical medicine and hygiene 2011;84(5):653-61.
2010: Jean-Paul Gonzalez; Micheline Guiserix; Frank Sauvage; Jean-Sébastien Guitton; Pierre Vidal; Nargès Bahi-Jaber; Hechmi Louzir; Dominique Pontier
Pathocenosis: a holistic approach to disease ecology.
EcoHealth 2010;7(2):237-41.
2010: A Meddeb-Garnaoui; A Toumi; H Ghelis; M Mahjoub; Hechmi Louzir; Mehdi Chenik
Cellular and humoral responses induced by Leishmania histone H2B and its divergent and conserved parts in cutaneous and visceral leishmaniasis patients, respectively.
Vaccine 2010;28(7):1881-6.
2009: Fouad Benhnini; Mehdi Chenik; Dhafer Laouini; Hechmi Louzir; Pierre André Cazenave; Koussay Dellagi
Comparative evaluation of two vaccine candidates against experimental leishmaniasis due to Leishmania major infection in four inbred mouse strains.
Clinical and vaccine immunology : CVI 2009;16(11):1529-37.
2009: Mélika Ben Ahmed; Mélika Ben Ahmed; Nicolette Moes; Sophie Buyse; Maha Abdeladhim; Hechmi Louzir; Nadine Cerf-Bensussan
IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6763-70.
2009: Inès Lakhal-Naouar; Thouraya Boussoffara; Amel Meddeb-Garnaoui; Yosser Ben Achour-Chenik; Hechmi Louzir; Mehdi Chenik
Cellular and humoral responses to Leishmania major virulence factors in healed cutaneous leishmaniasis and Mediterranean visceral leishmaniasis patients.
Clinical and vaccine immunology : CVI 2009;16(6):956-8.
2008: Inès Lakhal-Naouar; Yosser Ben Achour-Chenik; Yvan Boublik; Mounira Meddeb; Ahlem Aamouri; Abdellatif Fattoum; Hechmi Louzir; Mehdi Chenik
Identification and characterization of a new Leishmania major specific 3'nucleotidase/nuclease protein.
Biochemical and biophysical research communications 2008;375(1):54-8.
2008: M Ammar; M Mokni; S Boubaker; Amel El Gaied; A Ben Osman; Hechmi Louzir
Involvement of granzyme B and granulysin in the cytotoxic response in lichen planus.
Journal of cutaneous pathology 2008;35(7):630-4.
2008: Abderrahman Abdelkefi; Saloua Ladeb; Lamia Torjman; Tarek Ben Othman; Amel Lakhal; Neila Ben Romdhane; Halima El Omri; Moez Elloumi; Hatem Belaaj; Ramzi Jeddi; Lamia Aissaouï; Habib Ksouri; Assia Ben Hassen; Fahmi Msadek; Ali Saad; Mohamed Hsaïri; K Boukef; Ahlem Amouri; Hechmi Louzir; Koussay Dellagi; Abdeladhim Ben Abdeladhim
Single autologous stem-cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicenter randomized clinical trial.
Blood 2008;111(4):1805-10.
2007: Richard Reithinger; Jean-Claude Dujardin; Hechmi Louzir; Claude Pirmez; Bruce Alexander; Simon Brooker
Cutaneous leishmaniasis.
The Lancet infectious diseases 2007;7(9):581-96.
2007: Meriem Ouakad; Narges Bahi-Jaber; Mehdi Chenik; Koussay Dellagi; Hechmi Louzir
Selection of endogenous reference genes for gene expression analysis in Leishmania major developmental stages.
Parasitology research 2007;101(2):473-7.
2007: Chokri Maktouf; F Bchir; Hechmi Louzir; Moez Elloumi; Hela Ben Abid; M Mdhaffer; N Elleuch; Balkis Meddeb; Chokri Mhiri; Z Hassen; Fattouma Makni; Mohamed Abid; Ouahida Cherif; Lilia Rokbani; Taoufik Souissi; Aïcha Hafsia; Koussay Dellagi
[Clinical spectrum of cobalamin deficiency in Tunisia].
Annales de biologie clinique 2007;65(2):135-42.
2007: Meriem Ouakad; Mehdi Chenik; Yosser Ben Achour-Chenik; Hechmi Louzir; Koussay Dellagi
Gene expression analysis of wild Leishmania major isolates: identification of genes preferentially expressed in amastigotes.
Parasitology research 2007;100(2):255-64.
2006: Chokri Maktouf; Attouma Bchir; Hechmi Louzir; Moez Mdhaffer; Moez Elloumi; Hela Ben Abid; Balkis Meddeb; Fattouma Makni; Adnene Laatiri; Taoufik Soussi; Aïcha Hafsia; Koussay Dellagi
Megaloblastic anemia in North Africa.
Haematologica 2006;91(7):990-1.
2006: Mehdi Chenik; Sami Lakhal; N Ben Khalef; L Zribi; Hechmi Louzir; Koussay Dellagi
Approaches for the identification of potential excreted/secreted proteins of Leishmania major parasites.
Parasitology 2006;132(Pt 4):493-509.
2006: Mehdi Chenik; Hechmi Louzir; H Ksontini; A Dilou; I Abdmouleh; Koussay Dellagi
Vaccination with the divergent portion of the protein histone H2B of Leishmania protects susceptible BALB/c mice against a virulent challenge with Leishmania major.
Vaccine 2006;24(14):2521-9.
2006: Mehdi Chenik; Noura Chaabouni; Yosser Ben Achour-Chenik; Meriem Ouakad; Inès Lakhal-Naouar; Hechmi Louzir; Koussay Dellagi
Identification of a new developmentally regulated Leishmania major large RAB GTPase.
Biochemical and biophysical research communications 2006;341(2):541-8.
2006: S Gharsallah Chouchane; F Gorsane; Hechmi Louzir; M K Nakhla; Mohamed Marrakchi; H Fakhfakh
Development of a real-time PCR for Tomato yellow leaf curl Sardinia virus.
Acta virologica 2006;50(2):101-5.
2005: Afif Ben Salah; Hechmi Louzir; Sadok Chlif; Moncef Mokni; Amor Zaatour; Mohamed Raouene; Riadh Ben Ismail; Koussay Dellagi
The predictive validity of naturally acquired delayed-type hypersensitivity to leishmanin in resistance to Leishmania major-associated cutaneous leishmaniasis.
The Journal of infectious diseases 2005;192(11):1981-7.
2005: Mehdi Chenik; Feriel Douagi; Yosser Ben Achour; Noureddine Ben Khalef; Meriem Ouakad; Hechmi Louzir; Koussay Dellagi
Characterization of two different mucolipin-like genes from Leishmania major.
Parasitology research 2005;98(1):5-13.
2005: Lamia Kallel; Jalel Boubaker; Hechmi Louzir; Mélika Ben Ahmed; Atfa Sassi; Samir Boubaker; Bechir Zouari; Azza Filali
[Colonic expression of gamma-interferon and interleukin-10 in Crohn's disease and ulcerative colitis].
Presse médicale (Paris, France : 1983) 2005;34(1):8-12.
2004: Besma E C Babay; Hechmi Louzir; Chahnaz Kebaïer; Samir Boubaker; Koussay Dellagi; Pierre-André Cazenave
Inbred strains derived from feral mice reveal new pathogenic mechanisms of experimental leishmaniasis due to Leishmania major.
Infection and immunity 2004;72(8):4603-11.
2004: Mélika Ben Ahmed; Habib Houman; Mohamed Miled; Koussay Dellagi; Hechmi Louzir
Involvement of chemokines and Th1 cytokines in the pathogenesis of mucocutaneous lesions of Behçet's disease.
Arthritis and rheumatism 2004;50(7):2291-5.
2004: Thouraya Bousoffara; Hechmi Louzir; Afif Ben Salah; Koussay Dellagi
Analysis of granzyme B activity as a surrogate marker of Leishmania-specific cell-mediated cytotoxicity in zoonotic cutaneous leishmaniasis.
The Journal of infectious diseases 2004;189(7):1265-73.
2003: Sameh Sarray; Najet Srairi; Mohamed Hatmi; José Luis; Hechmi Louzir; Imed Regaya; Hmida Slema; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi
Lebecetin, a potent antiplatelet C-type lectin from Macrovipera lebetina venom.
Biochimica et biophysica acta 2003;1651(1-2):30-40.
2003: Ibtissem Abdmouleh Maalej; Mehdi Chenik; Hechmi Louzir; Afif Ben Salah; Chokri Bahloul; Fethi Amri; Koussay Dellagi
Comparative evaluation of ELISAs based on ten recombinant or purified Leishmania antigens for the serodiagnosis of Mediterranean visceral leishmaniasis.
The American journal of tropical medicine and hygiene 2003;68(3):312-20.
2003: Mélika Ben Ahmed; Habib Houman; Imed Ben Ghorbel; A Braham-Sfaxi; Mohamed Miled; Koussay Dellagi; Hechmi Louzir
Cytokine expression within mucocutaneous lesions of Behçet's disease: involvement of proinflammatory and Th1 cytokines.
Advances in experimental medicine and biology 2003;528():343-6.
2003: Mélika Ben Ahmed; Habib Houman; S Abdelhak; Imed Ben Ghorbel; Mohamed Miled; Koussay Dellagi; Hechmi Louzir
MICA transmembrane region polymorphism and HLA B51 in Tunisian Behçet's disease patients.
Advances in experimental medicine and biology 2003;528():225-8.
2002: Y Ben Achour; Mehdi Chenik; Hechmi Louzir; Koussay Dellagi
Identification of a disulfide isomerase protein of Leishmania major as a putative virulence factor.
Infection and immunity 2002;70(7):3576-85.
2001: C Kébaïer; Hechmi Louzir; Mehdi Chenik; Afif Ben Salah; Koussay Dellagi
Heterogeneity of wild Leishmania major isolates in experimental murine pathogenicity and specific immune response.
Infection and immunity 2001;69(8):4906-15.
2001: N Ben Alaya Bouafif; Afif Ben Salah; Hechmi Louzir; A Zaâtour; N Bel Haj Hamida; F Mighri; A Gharbi; Marina Gramiccia; Luigi Gradoni; Koussay Dellagi; R Ben Ismaïl
[Concordance of leishmaniasis cutaneous tests in Tunisia].
Archives de l'Institut Pasteur de Tunis 2001;78(1-4):11-6.
1999: B Babai; Hechmi Louzir; P A Cazenave; Koussay Dellagi
Depletion of peritoneal CD5+ B cells has no effect on the course of Leishmania major infection in susceptible and resistant mice.
Clinical and experimental immunology 1999;117(1):123-9.
1999: Atfa Sassi; Hechmi Louzir; Afif Ben Salah; Moncef Mokni; A Ben Osman; Koussay Dellagi
Leishmanin skin test lymphoproliferative responses and cytokine production after symptomatic or asymptomatic Leishmania major infection in Tunisia.
Clinical and experimental immunology 1999;116(1):127-32.
1999: MK Chahed; Afif Ben Salah; Hechmi Louzir; H Marrakchi; Amor Zaatour; A Ftaïti; B Ben Chaabane; M Sidhom; Koussay Dellagi; Riadh Ben Ismail
[Efficacy of intra-lesional glucantime in the treatment of zoonotic cutaneous leishmaniasis in basic health care conditions].
Archives de l'Institut Pasteur de Tunis 1999;76(1-4):13-8.
1998: Hechmi Louzir; Peter C Melby; Afif Ben Salah; H Marrakchi; Karim Aoun; Riadh Ben Ismail; Koussay Dellagi
Immunologic determinants of disease evolution in localized cutaneous leishmaniasis due to Leishmania major.
The Journal of infectious diseases 1998;177(6):1687-95.
1998: V Grunewald; M Bonnet; S Boutin; Tai-Tung Yip; Hechmi Louzir; M Levrero; Jean-Marie Seigneurin; M Raphael; R Touitou; Dominique Martel-Renoir; C Cochet; A Durandy; P Andre; W Lau; Y Zeng; Irene Joab
Amino-acid change in the Epstein-Barr-virus ZEBRA protein in undifferentiated nasopharyngeal carcinomas from Europe and North Africa.
International journal of cancer. Journal international du cancer 1998;75(4):497-503.
1995: S Abdelhak; Hechmi Louzir; J Timm; L Blel; Z Benlasfar; Micheline Lagranderie; M Gheorghiu; K Dellagi; Brigitte Gicquel
Recombinant BCG expressing the leishmania surface antigen Gp63 induces protective immunity against Leishmania major infection in BALB/c mice.
Microbiology (Reading, England) 1995;141 ( Pt 7)():1585-92.
1994: F Tebourski; A el Gaied; Hechmi Louzir; Riadh Ben Ismail; R Kammoun; Koussay Dellagi
Identification of an immunodominant 32-kilodalton membrane protein of Leishmania donovani infantum promastigotes suitable for specific diagnosis of Mediterranean visceral leishmaniasis.
Journal of clinical microbiology 1994;32(10):2474-80.
1994: Hechmi Louzir
[The role of Epstein-Barr virus in the development of visceral leishmaniasis].
Archives de l'Institut Pasteur de Tunis 1994;71(3-4):453-7.
1994: F Tebourski; Hechmi Louzir; A Ben Ammar-el Gaied; R Ben Ismaïl; Koussay Dellagi
[Identification of specific serologic markers in visceral leishmaniasis: anti-p32 antibody response].
Archives de l'Institut Pasteur de Tunis 1994;71(3-4):447-51.
1994: Hechmi Louzir; F Tebourski; Deborah Smith; R B Ismail; Koussay Dellagi
Antibodies to Leishmania donovani infantum heat-shock protein 70 in human visceral leishmaniasis.
The Journal of infectious diseases 1994;169(5):1183-4.
1994: Hechmi Louzir; L Belal-Kacemi; A Sassi; Dhafer Laouini; Riadh Ben Ismail; Koussay Dellagi
Natural autoantibodies, IgG antibodies to tetanus toxoid and CD5+ B cells in patients with Mediterranean visceral leishmaniasis. The Leishmania Study Group.
Clinical and experimental immunology 1994;95(3):479-84.
1994: A Gasmi; Hechmi Louzir; Habib Karoui; Mohamed El Ayeb; Koussay Dellagi
Purification from Vipera lebetina (desert adder) venom of a protein that depletes human complement.
Natural toxins 1994;2(1):44-8.
1993: Hechmi Louzir; H Triki; S Bennani; Léna Edelman; Dhafer Laouini; Riadh Ben Ismail; Irene Joab; Koussay Dellagi
Risk factors for visceral leishmaniasis: role of Epstein-Barr virus infection.
Archives de l'Institut Pasteur de Tunis 1993;70(3-4):357-62.
1992: André Galinowski; R Barbouche; P Truffinet; Hechmi Louzir; Marie-France Poirier; O Bouvet; Henri Loo; S Avrameas
Natural autoantibodies in schizophrenia.
Acta psychiatrica Scandinavica 1992;85(3):240-2.
1992: Hechmi Louzir; Therese Ternynck; Yousr Gorgi; S Tahar; Khaled Ayed; Stratis Avrameas
Autoantibodies and circulating immune complexes in sera from patients with hepatitis B virus-related chronic liver disease.
Clinical immunology and immunopathology 1992;62(2):160-7.
1990: P Matsiota; P Dosquet; Hechmi Louzir; E Druet; P Druet; Stratis Avrameas
IgA polyspecific autoantibodies in IgA nephropathy.
Clinical and experimental immunology 1990;79(3):361-6.
1988: Hechmi Louzir; Therese Ternynck; Yousr Gorgi; Khaled Ayed; Stratis Avrameas
Enzyme immunoassay analysis of antibody specificities present in the circulating immune complexes of selected pathological sera.
Journal of immunological methods 1988;114(1-2):145-53.