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Clare Futter

Research Profile

Anatomy

Chemicals & Drugs

Physiology

Living Beings

Procedures

Microscopy, Electron

Disorders

Choroideremia

Co-author Network

Publications

TOP 3
Bernadette Carroll; Reiko Daigaku; Ivan Dikic; Mattea Finelli; Richard E Francis; Marieke A Frasa; Clare Futter; Filipe Maximiano; Jessica McCormack; Noor Mohd-Naim; Louis Perdios; Sigrid B Thoresen; Vania M M Braga
The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy.
Rajesh K Singh; Tanya Tolmachova; Christina Wasmeier; Silene T Wavre-Shapton; Sergio D Catz; Clare Futter; Alistair N Hume; Koichi Mizuno; Chiara Recchi; Miguel C Seabra
Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion.
Tânia Martins; Ana P Silva; António F Ambrósio; Thomas Burgoyne; Clare Futter; John Greenwood; Natalie Hudson; Bridget-Ann Kenny; Patric Turowski
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.

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All Publications

2013: Bernadette Carroll; Reiko Daigaku; Ivan Dikic; Mattea Finelli; Richard E Francis; Marieke A Frasa; Clare Futter; Filipe Maximiano; Jessica McCormack; Noor Mohd-Naim; Louis Perdios; Sigrid B Thoresen; Vania M M Braga
The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy.
Developmental cell 2013;25(1):15-28.
2013: Rajesh K Singh; Tanya Tolmachova; Christina Wasmeier; Silene T Wavre-Shapton; Sergio D Catz; Clare Futter; Alistair N Hume; Koichi Mizuno; Chiara Recchi; Miguel C Seabra
Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion.
The FEBS journal 2013;280(3):892-903.
2013: Tânia Martins; Ana P Silva; António F Ambrósio; Thomas Burgoyne; Clare Futter; John Greenwood; Natalie Hudson; Bridget-Ann Kenny; Patric Turowski
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.
Neuropharmacology 2013;65():74-82.
2013: Silène T Wavre-Shapton; Tanya Tolmachova; Mafalda Lopes da Silva; Clare Futter; Miguel C Seabra
Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium.
PloS one 2013;8(2):e57769.
2013: Bethan S Kilpatrick; Emily R Eden; Clare Futter; Anthony H Schapira; Sandip Patel
Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals.
Journal of cell science 2013;126(Pt 1):60-6.
2012: Mafalda Lopes da Silva; José S Ramalho; Duarte C Barral; Laura Cabrita-Santos; Clare Futter; Carolina Thieleke-Matos; Silène T Wavre-Shapton; Miguel C Seabra
The host endocytic pathway is essential for Plasmodium berghei late liver stage development.
Traffic (Copenhagen, Denmark) 2012;13(10):1351-63.
2012: Emily R Eden; James R Edgar; Thomas Burgoyne; Alexander Sorkin; Clare Futter
The relationship between ER-multivesicular body membrane contacts and the ESCRT machinery.
Biochemical Society transactions 2012;40(2):464-8.
2012: Tanya Tolmachova; Dhani Tracey-White; Silene T Wavre-Shapton; Clare Futter; Oleg Tolmachov; Miguel C Seabra
CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the retinal pigment epithelium of choroideremia mice.
The journal of gene medicine 2012;14(3):158-68.
2012: Emily R Eden; Fangtian Huang; Alexander Sorkin; Clare Futter
The role of EGF receptor ubiquitination in regulating its intracellular traffic.
Traffic (Copenhagen, Denmark) 2012;13(2):329-37.
2010: Tanya Tolmachova; Silene T Wavre-Shapton; Alun R Barnard; Robert MacLaren; Clare Futter; Miguel C Seabra
Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia.
Investigative ophthalmology & visual science 2010;51(10):4913-20.
2010: Nicolas Carvou; Roman Holic; Michelle Li; Clare Futter; Alison Skippen; Shamshad Cockcroft
Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.
Journal of cell science 2010;123(Pt 8):1262-73.
2010: Horgan Conor; Sara R Hanscom; Rushee S Jolly; Clare Futter; Mary W McCaffrey
Rab11-FIP3 binds dynein light intermediate chain 2 and its overexpression fragments the Golgi complex.
Biochemical and biophysical research communications 2010;394(2):387-92.
2010: Horgan Conor; Sara R Hanscom; Rushee S Jolly; Clare Futter; Mary W McCaffrey
Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment.
Journal of cell science 2010;123(Pt 2):181-91.
2009: Ah-Lai Law; Qi Ling; Katherine A Hajjar; Clare Futter; John Greenwood; Peter Adamson; Silène T Wavre-Shapton; Stephen E Moss; Matthew J Hayes
Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.
Molecular biology of the cell 2009;20(17):3896-904.
2009: Emily R Eden; Ian J White; Clare Futter
Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies.
Biochemical Society transactions 2009;37(Pt 1):173-7.
2008: Philip G Woodman; Clare Futter
Multivesicular bodies: co-ordinated progression to maturity.
Current opinion in cell biology 2008;20(4):408-14.
2007: Vanda S Lopes; Christina Wasmeier; Miguel C Seabra; Clare Futter
Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis.
Molecular biology of the cell 2007;18(10):3914-27.
2007: Clare Futter; Ian J White
Annexins and endocytosis.
Traffic (Copenhagen, Denmark) 2007;8(8):951-8.
2007: Vanda S Lopes; José S Ramalho; Dylan Owen; Mike Karl; Olaf Strauss; Clare Futter; Miguel C Seabra
The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium.
Traffic (Copenhagen, Denmark) 2007;8(5):486-99.
2007: Tanya Tolmachova; Magnus Abrink; Clare Futter; Kalwant S Authi; Miguel C Seabra
Rab27b regulates number and secretion of platelet dense granules.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5872-7.
2007: Horgan Conor; Arkadiusz Oleksy; Alexander V Zhdanov; Patrick Y Lall; Ian J White; Amir R Khan; Clare Futter; John G McCaffrey; Mary W McCaffrey
Rab11-FIP3 is critical for the structural integrity of the endosomal recycling compartment.
Traffic (Copenhagen, Denmark) 2007;8(4):414-30.
2006: M Razi; Clare Futter
Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.
Molecular biology of the cell 2006;17(8):3469-83.
2006: Clare Futter
The molecular regulation of organelle transport in mammalian retinal pigment epithelial cells.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(2):104-11.
2006: Tanya Tolmachova; Ross Anders; Magnus Abrink; Laurence Bugeon; Margaret J Dallman; Clare Futter; José S Ramalho; Felix Tonagel; Naoyuki Tanimoto; Mathias W Seeliger; Clare Huxley; Miguel C Seabra
Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia.
The Journal of clinical investigation 2006;116(2):386-94.
2006: Ian J White; Lorna M Bailey; Minoo Razi Aghakhani; Stephen E Moss; Clare Futter
EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation.
The EMBO journal 2006;25(1):1-12.
2005: Jodhbir S Mehta; Clare Futter; Susan R Sandeman; Richard G A Faragher; Karin A Hing; Liz Tanner; Bruce D S Allan
Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials.
The British journal of ophthalmology 2005;89(10):1356-62.
2005: Clare Futter; Jonathan G Crowston; Bruce D S Allan
Interaction with collagen IV protects lens epithelial cells from Fas-dependent apoptosis by stimulating the production of soluble survival factors.
Investigative ophthalmology & visual science 2005;46(9):3256-62.
2004: Matthew Wherlock; Alexandra Gampel; Clare Futter; Harry Mellor
Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase.
Journal of cell science 2004;117(Pt 15):3221-31.
2004: Alejandra Tomas; Clare Futter; Stephen E Moss
Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.
The Journal of cell biology 2004;165(6):813-22.
2004: Clare Futter; José S Ramalho; Gesine B Jaissle; Mathias W Seeliger; Miguel C Seabra
The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells.
Molecular biology of the cell 2004;15(5):2264-75.
2001: Clare Futter; Lucy M Collinson; Jonathan M Backer; Colin Hopkins
Human VPS34 is required for internal vesicle formation within multivesicular endosomes.
The Journal of cell biology 2001;155(7):1251-64.
2000: Colin Hopkins; A Gibson; J Stinchcombe; Clare Futter
Chimeric molecules employing horseradish peroxidase as reporter enzyme for protein localization in the electron microscope.
Methods in enzymology 2000;327():35-45.
1998: A Gibson; Clare Futter; S Maxwell; E H Allchin; M Shipman; J P Kraehenbuhl; D Domingo; Charles (Greg) Odorizzi; IS Trowbridge; Colin Hopkins
Sorting mechanisms regulating membrane protein traffic in the apical transcytotic pathway of polarized MDCK cells.
The Journal of cell biology 1998;143(1):81-94.
1998: Clare Futter; A Gibson; E H Allchin; S Maxwell; L J Ruddock; Charles (Greg) Odorizzi; D Domingo; IS Trowbridge; Colin Hopkins
In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules.
The Journal of cell biology 1998;141(3):611-23.
1998: J Hirst; Clare Futter; Colin Hopkins
The kinetics of mannose 6-phosphate receptor trafficking in the endocytic pathway in HEp-2 cells: the receptor enters and rapidly leaves multivesicular endosomes without accumulating in a prelysosomal compartment.
Molecular biology of the cell 1998;9(4):809-16.
1998: K i Nagata; A Puls; Clare Futter; P Aspenstrom; Erik M Schaefer; T Nakata; N Hirokawa; Alan Hall
The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3.
The EMBO journal 1998;17(1):149-58.
1996: Clare Futter; A Pearse; L J Hewlett; Colin Hopkins
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes.
The Journal of cell biology 1996;132(6):1011-23.
1995: Clare Futter; CN Connolly; Daniel F Cutler; Colin Hopkins
Newly synthesized transferrin receptors can be detected in the endosome before they appear on the cell surface.
The Journal of biological chemistry 1995;270(18):10999-1003.
1994: CN Connolly; Clare Futter; A Gibson; Colin Hopkins; Daniel F Cutler
Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase.
The Journal of cell biology 1994;127(3):641-52.
1993: Clare Futter; M Marsh
Endocytosis and pasta.
Trends in cell biology 1993;3(9):316-8.
1993: Clare Futter; S Felder; Joseph Schlessinger; A Ullrich; Colin Hopkins
Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor.
The Journal of cell biology 1993;120(1):77-83.
1992: Clare Futter; D Panton; SC Kestin; David J Flint
Mechanism of action of cytotoxic antibodies to adipocytes on adipose tissue, liver and food intake in the rat.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1992;16(8):615-22.
1990: D Panton; Clare Futter; SC Kestin; D Flint
Increased growth and protein deposition in rats treated with antibodies to adipocytes.
The American journal of physiology 1990;258(6 Pt 1):E985-9.
1989: Clare Futter; Colin Hopkins
Subfractionation of the endocytic pathway: isolation of compartments involved in the processing of internalised epidermal growth factor-receptor complexes.
Journal of cell science 1989;94 ( Pt 4)():685-94.
1986: D J Flint; H Coggrave; Clare Futter; M J Gardner; T J Clarke
Stimulatory and cytotoxic effects of an antiserum to adipocyte plasma membranes on adipose tissue metabolism in vitro and in vivo.
International journal of obesity 1986;10(1):69-77.