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Angela Krämer

Research Profile

Physiology

RNA Splicing

Anatomy

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Ching-Jung Huang; Fabio Ferfoglia; Flore Raleff; Angela Krämer
Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.
Margherita Corioni; Nicolas Antih; Goranka Tanackovic; Mihaela Zavolan; Angela Krämer
Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing.
Angela Krämer; F Ferfoglia; C-J Huang; F Mulhaupt; Dobrila Nesic; Goranka Tanackovic
Structure-function analysis of the U2 snRNP-associated splicing factor SF3a.

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All Publications

2011: Ching-Jung Huang; Fabio Ferfoglia; Flore Raleff; Angela Krämer
Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.
The Journal of biological chemistry 2011;286(15):13106-14.
2011: Margherita Corioni; Nicolas Antih; Goranka Tanackovic; Mihaela Zavolan; Angela Krämer
Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing.
Nucleic acids research 2011;39(5):1868-79.
2005: Angela Krämer; F Ferfoglia; C-J Huang; F Mulhaupt; Dobrila Nesic; Goranka Tanackovic
Structure-function analysis of the U2 snRNP-associated splicing factor SF3a.
Biochemical Society transactions 2005;33(Pt 3):439-42.
2005: Goranka Tanackovic; Angela Krämer
Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.
Molecular biology of the cell 2005;16(3):1366-77.
2004: Jana Královicová; Sophie Houngninou-Molango; Angela Krämer; Igor Vorechovsky
Branch site haplotypes that control alternative splicing.
Human molecular genetics 2004;13(24):3189-202.
2004: Dobrila Nesic; Goranka Tanackovic; Angela Krämer
A role for Cajal bodies in the final steps of U2 snRNP biogenesis.
Journal of cell science 2004;117(Pt 19):4423-33.
2003: Philipp Selenko; Goran Gregorovic; Remco Sprangers; Gunter Stier; Zakaria Rhani; Angela Krämer; Michael Sattler
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.
Molecular cell 2003;11(4):965-76.
2001: Z Liu; I Luyten; Matthew J Bottomley; Ana C Messias; S Houngninou-Molango; Remco Sprangers; Katia Zanier; Angela Krämer; Michael Sattler
Structural basis for recognition of the intron branch site RNA by splicing factor 1.
Science (New York, N.Y.) 2001;294(5544):1098-102.
2001: Dobrila Nesic; Angela Krämer
Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.
Molecular and cellular biology 2001;21(19):6406-17.
1999: R Mazroui; A Puoti; Angela Krämer
Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viability.
RNA (New York, N.Y.) 1999;5(12):1615-31.
1999: X Wang; S Bruderer; Z Rafi; Jing Xue; Peter J Milburn; Angela Krämer; Phillip J Robinson
Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly.
The EMBO journal 1999;18(16):4549-59.
1999: Angela Krämer; P Grüter; K Gröning; B Kastner
Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP.
The Journal of cell biology 1999;145(7):1355-68.
1998: C F Kennedy; Angela Krämer; Susan M Berget
A role for SRp54 during intron bridging of small introns with pyrimidine tracts upstream of the branch point.
Molecular and cellular biology 1998;18(9):5425-34.
1998: Jean-Christophe Rain; Z Rafi; Zakaria Rhani; Pierre Legrain; Angela Krämer
Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1.
RNA (New York, N.Y.) 1998;4(5):551-65.
1998: Angela Krämer; M Quentin; F Mulhauser
Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene.
Gene 1998;211(1):29-37.
1998: Marion S Schmidt-Zachmann; S Knecht; Angela Krämer
Molecular characterization of a novel, widespread nuclear protein that colocalizes with spliceosome components.
Molecular biology of the cell 1998;9(1):143-60.
1996: S Arning; P Grüter; G Bilbe; Angela Krämer
Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.
RNA (New York, N.Y.) 1996;2(8):794-810.
1996: Jean-Christophe Rain; A M Tartakoff; Angela Krämer; Pierre Legrain
Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution.
RNA (New York, N.Y.) 1996;2(6):535-50.
1996: Angela Krämer
The structure and function of proteins involved in mammalian pre-mRNA splicing.
Annual review of biochemistry 1996;65():367-409.
1995: Angela Krämer; F Mulhauser; C Wersig; K Gröning; G Bilbe
Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae.
RNA (New York, N.Y.) 1995;1(3):260-72.
1994: Angela Krämer; P Legrain; F Mulhauser; K Gröning; R Brosi; G Bilbe
Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.
Nucleic acids research 1994;22(24):5223-8.
1993: R Brosi; K Gröning; S E Behrens; R Lührmann; Angela Krämer
Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9.
Science (New York, N.Y.) 1993;262(5130):102-5.
1993: R Brosi; Hans-Peter Hauri; Angela Krämer
Separation of splicing factor SF3 into two components and purification of SF3a activity.
The Journal of biological chemistry 1993;268(23):17640-6.
1993: Angela Krämer
Mammalian protein factors involved in nuclear pre-mRNA splicing.
Molecular biology reports 1993;18(2):93-8.
1992: Angela Krämer
Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex.
Molecular and cellular biology 1992;12(10):4545-52.
1992: U Utans; S E Behrens; R Lührmann; Ryszard Kole; Angela Krämer
A splicing factor that is inactivated during in vivo heat shock is functionally equivalent to the [U4/U6.U5] triple snRNP-specific proteins.
Genes & development 1992;6(4):631-41.
1992: M E Nemeroff; U Utans; Angela Krämer; Robert M Krug
Identification of cis-acting intron and exon regions in influenza virus NS1 mRNA that inhibit splicing and cause the formation of aberrantly sedimenting presplicing complexes.
Molecular and cellular biology 1992;12(3):962-70.
1990: U Utans; Angela Krämer
Splicing factor SF4 is dispensable for the assembly of a functional splicing complex and participates in the subsequent steps of the splicing reaction.
The EMBO journal 1990;9(12):4119-26.
1990: Angela Krämer; W Keller
Preparation and fractionation of mammalian extracts active in pre-mRNA splicing.
Methods in enzymology 1990;181():3-19.
1990: Angela Krämer
Site-specific degradation of RNA of small nuclear ribonucleoprotein particles with complementary oligodeoxynucleotides and RNase H.
Methods in enzymology 1990;181():284-92.
1990: Angela Krämer
Purification of small nuclear ribonucleoprotein particles active in RNA processing.
Methods in enzymology 1990;181():215-32.
1990: Angela Krämer; U Utans; Walter Keller; A Lamond
Components involved in nuclear pre-mRNA splicing.
Molecular biology reports 1990;14(2-3):199-200.
1988: Angela Krämer
Presplicing complex formation requires two proteins and U2 snRNP.
Genes & development 1988;2(9):1155-67.
1987: Angela Krämer; M Frick; Walter Keller
Separation of multiple components of HeLa cell nuclear extracts required for pre-messenger RNA splicing.
The Journal of biological chemistry 1987;262(36):17630-40.
1987: O Gick; Angela Krämer; A Vasserot; Max L Birnstiel
Heat-labile regulatory factor is required for 3' processing of histone precursor mRNAs.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):8937-40.
1987: Angela Krämer
Fractionation of HeLa cell nuclear extracts reveals minor small nuclear ribonucleoprotein particles.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8408-12.
1987: Angela Krämer
Analysis of RNase-A-resistant regions of adenovirus 2 major late precursor-mRNA in splicing extracts reveals an ordered interaction of nuclear components with the substrate RNA.
Journal of molecular biology 1987;196(3):559-73.
1987: D Frendewey; Angela Krämer; Walter Keller
Different small nuclear ribonucleoprotein particles are involved in different steps of splicing complex formation.
Cold Spring Harbor symposia on quantitative biology 1987;52():287-98.
1986: O Gick; Angela Krämer; W Keller; Max L Birnstiel
Generation of histone mRNA 3' ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction.
The EMBO journal 1986;5(6):1319-26.
1985: Angela Krämer; W Keller
Purification of a protein required for the splicing of pre-mRNA and its separation from the lariat debranching enzyme.
The EMBO journal 1985;4(13A):3571-81.
1985: Angela Krämer
5 S ribosomal gene transcription during Xenopus oogenesis.
Developmental biology (New York, N.Y. : 1985) 1985;1():431-51.
1984: Angela Krämer; W Keller; B Appel; R Lührmann
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors.
Cell 1984;38(1):299-307.
1983: Angela Krämer; R G Roeder
The use of monoclonal antibodies for the characterization of a 5 S gene-specific transcription factor (IIIA) from Xenopus laevis.
The Journal of biological chemistry 1983;258(19):11915-23.
1981: Angela Krämer; E K Bautz
Immunological relatedness of subunits of RNA polymerase II from insects and mammals.
European journal of biochemistry / FEBS 1981;117(3):449-55.
1980: Angela Krämer; R Haars; R Kabisch; H Will; F A Bautz; Ekkehard K F Bautz
Monoclonal antibody directed against RNA polymerase II of Drosophila melanogaster.
Molecular & general genetics : MGG 1980;180(1):193-9.