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Rosalie Pelz

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Zhiping Wang; Kerstin M Kampa-Schittenhelm; Yuangang Liu; Rosalie C Pelz; Brett C Sheppard; Philip J S Stork; Maho Takahashi; Kathryn Van Hook; Charles D Lopez
N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.
Deanne Tibbitts; Xiaoli Zhang; Julienne Escamilla-Powers; Rosalie C Pelz
Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity.
Kishore B Challagundla; Tiffany DeVine; Rosalie C Pelz; Xiao-Xin Sun; Qinghong Zhang; Xiaoli Zhang; Mushui Dai
Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stress.

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All Publications

2013: Zhiping Wang; Kerstin M Kampa-Schittenhelm; Yuangang Liu; Rosalie C Pelz; Brett C Sheppard; Philip J S Stork; Maho Takahashi; Kathryn Van Hook; Charles D Lopez
N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(1):312-7.
2012: Deanne Tibbitts; Xiaoli Zhang; Julienne Escamilla-Powers; Rosalie C Pelz
Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity.
Blood 2012;119(22):5334-5.
2011: Kishore B Challagundla; Tiffany DeVine; Rosalie C Pelz; Xiao-Xin Sun; Qinghong Zhang; Xiaoli Zhang; Mushui Dai
Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stress.
Molecular and cellular biology 2011;31(19):4007-21.
2010: Gabrielle H Ashton; Jennifer P Morton; Kevin Myant; Toby J Phesse; Rachel A Ridgway; Victoria Marsh; Julie A Wilkins; Dimitris Athineos; Vanesa Muncan; Richard Kemp; Kristi Neufeld; Hans Clevers; Valerie G Brunton; Douglas J Winton; Xiaoyan Wang; Rosalie C Pelz; Alan R Clarke; Margaret C Frame; Owen J Sansom
Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Developmental cell 2010;19(2):259-69.
2010: Julienne Escamilla-Powers; Colin J Daniel; Amy Farrell; Karyn Taylor; Xiaoli Zhang; Sarah Byers; Rosalie C Pelz
The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.
The Journal of biological chemistry 2010;285(7):4847-58.
2009: Hugh Arnold; Xiaoli Zhang; Colin J Daniel; Deanne Tibbitts; Julienne Escamilla-Powers; Amy Farrell; Sara Tokarz; Charlie Morgan; Rosalie C Pelz
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc.
The EMBO journal 2009;28(5):500-12.
2009: Archana Mukhopadhyay; Sahar A Saddoughi; Pengfei Song; Iyad Sultan; Suriyan Ponnusamy; Can E Senkal; Christopher F Snook; Hugh Arnold; Rosalie C Pelz; Yusuf A Hannun; Besim Ogretmen
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(3):751-63.
2008: Hugh Arnold; Rosalie C Pelz
A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.
Cancer metastasis reviews 2008;27(2):147-58.
2008: Carl R Pelz; Molly Kulesz-Martin; Grover C Bagby; Rosalie C Pelz
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data.
BMC bioinformatics 2008;9():520.
2007: Mushui Dai; Rosalie C Pelz; Hua lu
Feedback regulation of c-Myc by ribosomal protein L11.
Cell cycle (Georgetown, Tex.) 2007;6(22):2735-41.
2007: Jennifer O'Neil; Jonathan Grim; Peter Strack; Sudhir Rao; Deanne Tibbitts; Christopher Winter; James Hardwick; Markus Welcker; Jules P P Meijerink; Rob Pieters; Giulio F Draetta; Rosalie C Pelz; Bruce E Clurman; A Thomas Look
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
The Journal of experimental medicine 2007;204(8):1813-24.
2007: J Ma; Hugh Arnold; Michael Lilly; Rosalie C Pelz; Andrew Kraft
Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Oncogene 2007;26(35):5145-53.
2007: Mushui Dai; Hugh Arnold; Xiao-Xin Sun; Rosalie C Pelz; Hua lu
Inhibition of c-Myc activity by ribosomal protein L11.
The EMBO journal 2007;26(14):3332-45.
2007: Melissa R Junttila; Pietri Puustinen; Minna Niemelä; Raija Ahola; Hugh Arnold; Trine Böttzauw; Risto Ala-Aho; Christina Nielsen; Johanna Ivaska; Yoichi Taya; Shi-Long Lu; Shujun Lin; Edward Chan; Xiao-Jing Wang; Reidar Grènman; Juergen Kast; Tuula Kallunki; Rosalie C Pelz; Veli-Matti Kähäri; Jukka Westermarck
CIP2A inhibits PP2A in human malignancies.
Cell 2007;130(1):51-62.
2007: Julienne Escamilla-Powers; Rosalie C Pelz
A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast.
The Journal of biological chemistry 2007;282(8):5432-42.
2006: Suman Malempati; Deanne Tibbitts; M Cunningham; Y Akkari; Susan B Olson; Guang Fan; Rosalie C Pelz
Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias.
Leukemia 2006;20(9):1572-81.
2006: Hugh Arnold; Rosalie C Pelz
Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.
Molecular and cellular biology 2006;26(7):2832-44.
2005: Molly Kulesz-Martin; James Lagowski; Suzanne Fei; Carl Pelz; Rosalie C Pelz; Marianne Powell; Ruth Halaban; Jodi Johnson
Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2005;10(2):142-52.
2004: Rosalie C Pelz
The life cycle of C-myc: from synthesis to degradation.
Cell cycle (Georgetown, Tex.) 2004;3(9):1133-7.
2004: Elizabeth Yeh; Melissa Cunningham; Hugh Arnold; Dawn Chasse; Teresa Monteith; Giovanni Ivaldi; William C Hahn; P Todd Stukenberg; Shirish Shenolikar; Takafumi Uchida; Christopher M Counter; Joseph R Nevins; Anthony R Means; Rosalie C Pelz
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
Nature cell biology 2004;6(4):308-18.
2002: David T Duong; Mary Waltner-Law; Rosalie C Pelz; Linda Sealy; Daryl K Granner
Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter.
The Journal of biological chemistry 2002;277(35):32234-42.
2002: Rosalie C Pelz; Joseph R Nevins
Signaling networks that link cell proliferation and cell fate.
The Journal of biological chemistry 2002;277(14):11617-20.
2001: Gustavo Leone; Rosalie C Pelz; Erich Huang; Rachel E Rempel; F Nuckolls; C H Park; Paloma H Giangrande; Lizhao Wu; Harold I Saavedra; Seth J Field; M A Thompson; H Yang; Y Fujiwara; Michael E Greenberg; Stuart H Orkin; Clay Smith; Joseph R Nevins
Myc requires distinct E2F activities to induce S phase and apoptosis.
Molecular cell 2001;8(1):105-13.
2001: D Zhuo; W D Zhao; Fred A Wright; H Y Yang; J P Wang; Rosalie C Pelz; T Baer; D H Kwon; D Gordon; S Gibbs; D Dai; Q Yang; J Spitzner; Ralf Krahe; Don Stredney; A Stutz; B Yuan
Assembly, annotation, and integration of UNIGENE clusters into the human genome draft.
Genome research 2001;11(5):904-18.
2001: Fred A Wright; William J Lemon; W D Zhao; Rosalie C Pelz; D Zhuo; J P Wang; H Y Yang; T Baer; Don Stredney; J Spitzner; A Stutz; Ralf Krahe; B Yuan
A draft annotation and overview of the human genome.
Genome biology 2001;2(7):RESEARCH0025.
2000: Rosalie C Pelz; F Nuckolls; Eric Haura; Y Taya; Katsuyuki Tamai; Joseph R Nevins
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.
Genes & development 2000;14(19):2501-14.
2000: M R Adams; Rosalie C Pelz; F Nuckolls; Gustavo Leone; Joseph R Nevins
Complex transcriptional regulatory mechanisms control expression of the E2F3 locus.
Molecular and cellular biology 2000;20(10):3633-9.
2000: Gustavo Leone; F Nuckolls; Seiichi Ishida; M Adams; Rosalie C Pelz; L Jakoi; alexander miron; Joseph R Nevins
Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Molecular and cellular biology 2000;20(10):3626-32.
1999: Rosalie C Pelz; Gustavo Leone; James DeGregori; Joseph R Nevins
Ras enhances Myc protein stability.
Molecular cell 1999;3(2):169-79.
1997: Rosalie C Pelz; K Ohtani; Joseph R Nevins
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals.
Molecular and cellular biology 1997;17(9):5227-35.
1997: Gustavo Leone; James DeGregori; Rosalie C Pelz; L Jakoi; Joseph R Nevins
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Nature 1997;387(6631):422-6.
1994: Stephen R Hann; M Dixit; Rosalie C Pelz; Linda Sealy
The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site.
Genes & development 1994;8(20):2441-52.
1994: Rosalie C Pelz; Linda Sealy
Multiple forms of C/EBP beta bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat.
Molecular and cellular biology 1994;14(7):4855-71.
1992: Rosalie C Pelz; Linda Sealy
Characterization of nuclear proteins that bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat.
Journal of virology 1992;66(11):6338-52.
1989: Rosalie C Pelz; M W Kaplan
Axial diffusion of retinol in isolated frog rod outer segments following substantial bleaches of visual pigment.
Vision research 1989;29(11):1485-92.
1988: Rosalie C Pelz; Gary Ciment
Changes in the migratory properties of neural crest and early crest-derived cells in vivo following treatment with a phorbol ester drug.
Developmental biology 1988;130(1):133-43.