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George Kemble
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Research Profile (preview)
Chemicals & Drugs
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Network (preview)
20
Jin, Hong
13
Greenberg, Harry
12
Arvin, Ann
11
Holmes, Tyson
10
Dekker, Cornelia
10
Mahmood, Kutubuddin
8
He, Xiao-Song
8
Duke, Gregory
7
Subbarao, Kanta
7
Lu, Bin
6
Spaete, Richard
6
Mocarski, Edward
6
Zhou, Helen Zhuoyuan
5
McAuliffe, Josephine
5
Murphy, Brian
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Geonetwork of George Kemble (preview)
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All Publications
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2009: Liu Jonathan; Shi Xiao; Schwartz Richard; Kemble George
Use of MDCK cells for production of live attenuated influenza vaccine.
Vaccine 2009;27(46):6460-3.
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2009: Karron Ruth A; Talaat Kawsar; Luke Catherine; Callahan Karen; Thumar Bhagvanji; Dilorenzo Susan; McAuliffe Josephine; Schappell Elizabeth; Suguitan Amorsolo; Mills Kimberly; Chen Grace; Lamirande Elaine; Coelingh Kathleen; Jin Hong; Murphy Brian R; Kemble George; Subbarao Kanta
Evaluation of two live attenuated cold-adapted H5N1 influenza virus vaccines in healthy adults.
Vaccine 2009;27(36):4953-60.
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2009: Talaat Kawsar R; Karron Ruth A; Callahan Karen A; Luke Catherine J; DiLorenzo Susan C; Chen Grace L; Lamirande Elaine W; Jin Hong; Coelingh Kathy L; Murphy Brian R; Kemble George; Subbarao Kanta
A live attenuated H7N3 influenza virus vaccine is well tolerated and immunogenic in a Phase I trial in healthy adults.
Vaccine 2009;27(28):3744-53.
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2009: Karron Ruth A; Callahan Karen; Luke Catherine; Thumar Bhagvanji; McAuliffe Josephine; Schappell Elizabeth; Joseph Tomy; Coelingh Kathleen; Jin Hong; Kemble George; Murphy Brian R; Subbarao Kanta
A live attenuated H9N2 influenza vaccine is well tolerated and immunogenic in healthy adults.
The Journal of infectious diseases 2009;199(5):711-6.
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2009: Chen Zhongying; Santos Celia; Aspelund Amy; Gillim-Ross Laura; Jin Hong; Kemble George; Subbarao Kanta
Evaluation of live attenuated influenza a virus h6 vaccines in mice and ferrets.
Journal of virology 2009;83(1):65-72.
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2009: Cheng Xing; Eisenbraun Michael; Xu Qi; Zhou Helen; Kulkarni Deepali; Subbarao Kanta; Kemble George; Jin Hong
H5N1 vaccine-specific B cell responses in ferrets primed with live attenuated seasonal influenza vaccines.
PloS one 2009;4(2):e4436.
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2008: Gillim-Ross Laura; Santos Celia; Chen Zhongying; Aspelund Amy; Yang Chin-Fen; Ye Dan; Jin Hong; Kemble George; Subbarao Kanta
Avian influenza h6 viruses productively infect and cause illness in mice and ferrets.
Journal of virology 2008;82(21):10854-63.
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2008: Chen Zhongying; Aspelund Amy; Kemble George; Jin Hong
Molecular studies of temperature-sensitive replication of the cold-adapted B/Ann Arbor/1/66, the master donor virus for live attenuated influenza FluMist vaccines.
Virology 2008;380(2):354-62.
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2008: Chan Winnie; Zhou Helen; Kemble George; Jin Hong
The cold adapted and temperature sensitive influenza A/Ann Arbor/6/60 virus, the master donor virus for live attenuated influenza vaccines, has multiple defects in replication at the restrictive temperature.
Virology 2008;380(2):304-11.
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2008: Levin Myron J; Song Lin-Ye; Fenton Terrence; Nachman Sharon; Patterson Julie; Walker Robert; Kemble George; Allende Maria; Hultquist Micki; Yi Tingting; Nowak Barbara; Weinberg Adriana
Shedding of live vaccine virus, comparative safety, and influenza-specific antibody responses after administration of live attenuated and inactivated trivalent influenza vaccines to HIV-infected children.
Vaccine 2008;26(33):4210-7.
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2008: Joseph Tomy; McAuliffe Josephine; Lu Bin; Vogel Leatrice; Swayne David; Jin Hong; Kemble George; Subbarao Kanta
A live attenuated cold-adapted influenza A H7N3 virus vaccine provides protection against homologous and heterologous H7 viruses in mice and ferrets.
Virology 2008;378(1):123-32.
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2008: He Xiao-Song; Holmes Tyson H; Mahmood Kutubuddin; Kemble George W; Dekker Cornelia L; Arvin Ann M; Greenberg Harry B
Phenotypic changes in influenza-specific CD8+ T cells after immunization of children and adults with influenza vaccines.
The Journal of infectious diseases 2008;197(6):803-11.
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2008: Sasaki Sanae; He Xiao-Song; Holmes Tyson H; Dekker Cornelia L; Kemble George W; Arvin Ann M; Greenberg Harry B
Influence of prior influenza vaccination on antibody and B-cell responses.
PloS one 2008;3(8):e2975.
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2008: He Xiao-Song; Holmes Tyson H; Sasaki Sanae; Jaimes Maria C; Kemble George W; Dekker Cornelia L; Arvin Ann M; Greenberg Harry B
Baseline levels of influenza-specific CD4 memory T-cells affect T-cell responses to influenza vaccines.
PloS one 2008;3(7):e2574.
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2007: Jin H; Manetz S; Leininger J; Luke C; Subbarao K; Murphy B; Kemble G; Coelingh K L
Toxicological evaluation of live attenuated, cold-adapted H5N1 vaccines in ferrets.
Vaccine 2007;25(52):8664-72.
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2007: Joseph Tomy; McAuliffe Josephine; Lu Bin; Jin Hong; Kemble George; Subbarao Kanta
Evaluation of replication and pathogenicity of avian influenza a H7 subtype viruses in a mouse model.
Journal of virology 2007;81(19):10558-66.
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2007: Belshe Robert B; Edwards Kathryn M; Vesikari Timo; Black Steven V; Walker Robert E; Hultquist Micki; Kemble George; Connor Edward M;
Live attenuated versus inactivated influenza vaccine in infants and young children.
The New England journal of medicine 2007;356(7):685-96.
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2007: Zeman Alenka M; Holmes Tyson H; Stamatis Shaye; Tu Wenwei; He Xiao-Song; Bouvier Nancy; Kemble George; Greenberg Harry B; Lewis David B; Arvin Ann M; Dekker Cornelia L
Humoral and cellular immune responses in children given annual immunization with trivalent inactivated influenza vaccine.
The Pediatric infectious disease journal 2007;26(2):107-15.
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2007: Sasaki Sanae; Jaimes Maria C; Holmes Tyson H; Dekker Cornelia L; Mahmood Kutubuddin; Kemble George W; Arvin Ann M; Greenberg Harry B
Comparison of the influenza virus-specific effector and memory B-cell responses to immunization of children and adults with live attenuated or inactivated influenza virus vaccines.
Journal of virology 2007;81(1):215-28.
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2006: He Xiao-Song; Holmes Tyson H; Zhang Caiqiu; Mahmood Kutubuddin; Kemble George W; Lewis David B; Dekker Cornelia L; Greenberg Harry B; Arvin Ann M
Cellular immune responses in children and adults receiving inactivated or live attenuated influenza vaccines.
Journal of virology 2006;80(23):11756-66.
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2006: Lu Bin; Zhou Helen; Chan Winnie; Kemble George; Jin Hong
Single amino acid substitutions in the hemagglutinin of influenza A/Singapore/21/04 (H3N2) increase virus growth in embryonated chicken eggs.
Vaccine 2006;24(44-46):6691-3.
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2006: Suguitan Amorsolo L; McAuliffe Josephine; Mills Kimberly L; Jin Hong; Duke Greg; Lu Bin; Luke Catherine J; Murphy Brian; Swayne David E; Kemble George; Subbarao Kanta
Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets.
PLoS medicine 2006;3(9):e360.
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2006: Klein Nicola P; Holmes Tyson H; Sharp Margaret A; Heineman Thomas C; Schleiss Mark R; Bernstein David I; Kemble George; Arvin Ann M; Dekker Cornelia L
Variability and gender differences in memory T cell immunity to varicella-zoster virus in healthy adults.
Vaccine 2006;24(33-34):5913-8.
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2006: Heineman Thomas C; Schleiss Mark; Bernstein David I; Spaete Richard R; Yan Lihan; Duke Greg; Prichard Mark; Wang Zhaoti; Yan Qing; Sharp Margaret A; Klein Nicola; Arvin Ann M; Kemble George
A phase 1 study of 4 live, recombinant human cytomegalovirus Towne/Toledo chimeric vaccines.
The Journal of infectious diseases 2006;193(10):1350-60.
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2006: Chen Zhongying; Aspelund Amy; Kemble George; Jin Hong
Genetic mapping of the cold-adapted phenotype of B/Ann Arbor/1/66, the master donor virus for live attenuated influenza vaccines (FluMist).
Virology 2006;345(2):416-23.
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2005: Prichard Mark N; Kaiwar Ravi; Jackman Winthrop T; Quenelle Debra C; Collins Deborah J; Kern Earl R; Kemble George M; Spaete Richard R
Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs.
Vaccine 2005;23(46-47):5424-31.
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2005: Hoffmann Erich; Mahmood Kutubuddin; Chen Zhongying; Yang Chin-Fen; Spaete Joshua; Greenberg Harry B; Herlocher M Louise; Jin Hong; Kemble George
Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66.
Journal of virology 2005;79(17):11014-21.
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2005: Lu Bin; Zhou Helen; Ye Dan; Kemble George; Jin Hong
Improvement of influenza A/Fujian/411/02 (H3N2) virus growth in embryonated chicken eggs by balancing the hemagglutinin and neuraminidase activities, using reverse genetics.
Journal of virology 2005;79(11):6763-71.
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2005: Jin Hong; Zhou Helen; Liu Hui; Chan Winnie; Adhikary Lopa; Mahmood Kutubuddin; Lee Min-Shi; Kemble George
Two residues in the hemagglutinin of A/Fujian/411/02-like influenza viruses are responsible for antigenic drift from A/Panama/2007/99.
Virology 2005;336(1):113-9.
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2005: Prichard Mark N; Lawlor Heather; Duke Gregory M; Mo Chengjun; Wang Zhaoti; Dixon Melissa; Kemble George; Kern Earl R
Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA.
Virology journal 2005;2():55.
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2004: He Xiao-Song; Draghi Monia; Mahmood Kutubuddin; Holmes Tyson H; Kemble George W; Dekker Cornelia L; Arvin Ann M; Parham Peter; Greenberg Harry B
T cell-dependent production of IFN-gamma by NK cells in response to influenza A virus.
The Journal of clinical investigation 2004;114(12):1812-9.
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2004: Mendelman Paul M; Rappaport Ruth; Cho Iksung; Block Stan; Gruber William; August Marilyn; Dawson Denise; Cordova Julie; Kemble George; Mahmood Kutubuddin; Palladino Giuseppe; Lee Min-Shi; Razmpour Ahmad; Stoddard Jeffrey; Forrest Bruce D
Live attenuated influenza vaccine induces cross-reactive antibody responses in children against an a/Fujian/411/2002-like H3N2 antigenic variant strain.
The Pediatric infectious disease journal 2004;23(11):1053-5.
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2004: Lee Min-Shi; Mahmood Kutubuddin; Adhikary Lopa; August Marilyn J; Cordova Julie; Cho Iksung; Kemble George; Reisinger Keith; Walker Robert E; Mendelman Paul M
Measuring antibody responses to a live attenuated influenza vaccine in children.
The Pediatric infectious disease journal 2004;23(9):852-6.
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2004: Wang Zhaoti; Mo Chengjun; Kemble George; Duke Gregory
Development of an efficient fluorescence-based microneutralization assay using recombinant human cytomegalovirus strains expressing green fluorescent protein.
Journal of virological methods 2004;120(2):207-15.
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2004: Chen Sharon F; Tu Wen-Wei; Sharp Margaret A; Tongson Eileen Cordoba; He Xiao-Song; Greenberg Harry B; Holmes Tyson H; Wang Zhaoti; Kemble George; Manganello Anne-Marie; Adler Stuart P; Dekker Cornelia L; Lewis David B; Arvin Ann M
Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood.
The Journal of infectious diseases 2004;189(9):1619-27.
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2004: Tu Wenwei; Chen Sharon; Sharp Margaret; Dekker Corry; Manganello Anne Marie; Tongson Eileen C; Maecker Holden T; Holmes Tyson H; Wang Zhaoti; Kemble George; Adler Stuart; Arvin Ann; Lewis David B
Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3260-7.
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2004: Jin Hong; Zhou Helen; Lu Bin; Kemble George
Imparting temperature sensitivity and attenuation in ferrets to A/Puerto Rico/8/34 influenza virus by transferring the genetic signature for temperature sensitivity from cold-adapted A/Ann Arbor/6/60.
Journal of virology 2004;78(2):995-8.
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2003: Jin Hong; Cheng Xing; Traina-Dorge Vicki L; Park Hyun Jung; Zhou Helen; Soike Ken; Kemble George
Evaluation of recombinant respiratory syncytial virus gene deletion mutants in African green monkeys for their potential as live attenuated vaccine candidates.
Vaccine 2003;21(25-26):3647-52.
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2003: Kemble George; Greenberg Harry
Novel generations of influenza vaccines.
Vaccine 2003;21(16):1789-95.
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2003: He Xiao-Song; Mahmood Kutubuddin; Maecker Holden T; Holmes Tyson H; Kemble George W; Arvin Ann M; Greenberg Harry B
Analysis of the frequencies and of the memory T cell phenotypes of human CD8+ T cells specific for influenza A viruses.
The Journal of infectious diseases 2003;187(7):1075-84.
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2003: Jin Hong; Lu Bin; Zhou Helen; Ma Chienhui; Zhao Jackie; Yang Chin-fen; Kemble George; Greenberg Harry
Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60.
Virology 2003;306(1):18-24.
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2002: Hoffmann Erich; Mahmood Kutubuddin; Yang Chin-Fen; Webster Robert G; Greenberg Harry B; Kemble George
Rescue of influenza B virus from eight plasmids.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11411-6.
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2002: Chou Sunwen; Waldemer Rachel H; Senters Anne E; Michels Kevin S; Kemble George W; Miner Richard C; Drew W Lawrence
Cytomegalovirus UL97 phosphotransferase mutations that affect susceptibility to ganciclovir.
The Journal of infectious diseases 2002;185(2):162-9.
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2001: Prichard M N; Penfold M E; Duke G M; Spaete R R; Kemble G W
A review of genetic differences between limited and extensively passaged human cytomegalovirus strains.
Reviews in medical virology 2001;11(3):191-200.
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2000: Kemble G W; Annunziato P; Lungu O; Winter R E; Cha T A; Silverstein S J; Spaete R R
Open reading frame S/L of varicella-zoster virus encodes a cytoplasmic protein expressed in infected cells.
Journal of virology 2000;74(23):11311-21.
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1999: Penfold M E; Dairaghi D J; Duke G M; Saederup N; Mocarski E S; Kemble G W; Schall T J
Cytomegalovirus encodes a potent alpha chemokine.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9839-44.
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1996: Mocarski E S; Kemble G W; Lyle J M; Greaves R F
A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11321-6.
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1996: Kemble G; Duke G; Winter R; Spaete R
Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids.
Journal of virology 1996;70(3):2044-8.
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1996: Cha T A; Tom E; Kemble G W; Duke G M; Mocarski E S; Spaete R R
Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.
Journal of virology 1996;70(1):78-83.
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1996: Mocarski E S; Kemble G W
Recombinant cytomegaloviruses for study of replication and pathogenesis.
Intervirology 1996;39(5-6):320-30.
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1994: Kemble G W; Danieli T; White J M
Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion.
Cell 1994;76(2):383-91.
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1993: Kemble G W; Henis Y I; White J M
GPI- and transmembrane-anchored influenza hemagglutinin differ in structure and receptor binding activity.
The Journal of cell biology 1993;122(6):1253-65.
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1992: Kemble G W; Bodian D L; Rosé J; Wilson I A; White J M
Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutinin.
Journal of virology 1992;66(8):4940-50.
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1989: Kemble G W; Mocarski E S
A host cell protein binds to a highly conserved sequence element (pac-2) within the cytomegalovirus a sequence.
Journal of virology 1989;63(11):4715-28.
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1987: Kemble G W; McCormick A L; Pereira L; Mocarski E S
A cytomegalovirus protein with properties of herpes simplex virus ICP8: partial purification of the polypeptide and map position of the gene.
Journal of virology 1987;61(10):3143-51.
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1982: Goodall A H; Kemble G; O'Brien D P; Rawlings E; Rotblat F; Russell G C; Janossy G; Tuddenham E G
Preparation of factor IX deficient human plasma by immunoaffinity chromatography using a monoclonal antibody.
Blood 1982;59(3):664-70.
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