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Brendan Buckley

Research Profile

Chemicals & Drugs

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Disorders

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Mendelian Randomization Analysis

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Iris Postmus; Naveed Sattar; P Eline Slagboom; David J Stott; Stella Trompet; Rudi G J Westendorp; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema
PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.
Jeffrey J W Verschuren; Brendan M Buckley; Joris Deelen; Ian Ford; Henk-Jan Guchelaar; Bas Heijmans; Jeanine J Houwing-Duistermaat; Naveed Sattar; P Eline Slagboom; David J Stott; Stella Trompet; J Wouter Jukema
Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.
Paul Welsh; Eliana Polisecki; Michele Robertson; Sabine Jahn; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G J Westendorp; James Shepherd; Aroon D Hingorani; George Davey Smith; Ernst Schaefer; Naveed Sattar
Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach.

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All Publications

2013: Iris Postmus; Naveed Sattar; P Eline Slagboom; David J Stott; Stella Trompet; Rudi G J Westendorp; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema
PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population.
Journal of lipid research 2013;54(2):561-6.
2013: Jeffrey J W Verschuren; Brendan M Buckley; Joris Deelen; Ian Ford; Henk-Jan Guchelaar; Bas Heijmans; Jeanine J Houwing-Duistermaat; Naveed Sattar; P Eline Slagboom; David J Stott; Stella Trompet; J Wouter Jukema
Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.
PloS one 2013;8(2):e56262.
2010: Paul Welsh; Eliana Polisecki; Michele Robertson; Sabine Jahn; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G J Westendorp; James Shepherd; Aroon D Hingorani; George Davey Smith; Ernst Schaefer; Naveed Sattar
Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach.
The Journal of clinical endocrinology and metabolism 2010;95(1):93-9.
2010: Stella Trompet; Peter van Vliet; Anton J M de Craen; Jelle Jolles; Brendan M Buckley; Michael B Murphy; Ian Ford; Peter W Macfarlane; Naveed Sattar; Chris J Packard; David J Stott; Jim Shepherd; E L E M Bollen; Gerard J Blauw; J Wouter Jukema; Rudi G J Westendorp
Pravastatin and cognitive function in the elderly. Results of the PROSPER study.
Journal of neurology 2010;257(1):85-90.
2009: Naveed Sattar; Heather M Murray; Paul Welsh; Gerard J Blauw; Brendan M Buckley; Stuart Cobbe; Anton J M de Craen; GD Lowe; J Wouter Jukema; Peter W Macfarlane; Michael B. Murphy; David J Stott; Rudi G J Westendorp; James Shepherd; Ian Ford; Chris J Packard
Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?
PLoS medicine 2009;6(6):e1000099.
2009: Naveed Sattar; Heather M Murray; P Welsh; Gerard J Blauw; Brendan M Buckley; Anton J M de Craen; Ian Ford; Nita G Forouhi; Dilys J Freeman; J Wouter Jukema; Peter W Macfarlane; Michael B. Murphy; Chris J Packard; David J Stott; R G J Westendorp; James Shepherd
Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly.
Diabetologia 2009;52(2):235-9.
2009: Paul Welsh; Heather M Murray; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G J Westendorp; James Shepherd; Naveed Sattar
Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population.
Diabetes care 2009;32(2):308-10.
2009: Ian Ford; Vladimir Bezlyak; David J Stott; Naveed Sattar; Chris J Packard; Ivan Perry; Brendan M Buckley; J Wouter Jukema; Anton J M de Craen; Rudi G J Westendorp; James Shepherd
Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis.
PLoS medicine 2009;6(1):e16.
2008: Stella Trompet; J Wouter Jukema; Ian Ford; James Shepherd; Jacobijn Gussekloo; Brendan M Buckley; Rudi G J Westendorp; Anton J M de Craen
Statins and blood pressure.
Archives of internal medicine 2008;168(21):2383.
2008: S Trompet; Anton J M de Craen; P Eline Slagboom; James Shepherd; Gerard J Blauw; Michael B. Murphy; E L E M Bollen; Brendan M Buckley; Ian Ford; Allan Gaw; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G J Westendorp; J Wouter Jukema
Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study.
Experimental gerontology 2008;43(8):801-5.
2008: Naveed Sattar; Alex McConnachie; A Gerald Shaper; Gerard J Blauw; Brendan M Buckley; Anton J M de Craen; Ian Ford; Nita G Forouhi; Dilys J Freeman; J Wouter Jukema; Lucy Lennon; Peter W Macfarlane; Michael B. Murphy; Chris J Packard; David J Stott; Rudi G J Westendorp; Peter H Whincup; James Shepherd; S Goya Wannamethee
Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies.
Lancet 2008;371(9628):1927-35.
2007: Chris J Packard; Rudi G J Westendorp; David J Stott; Muriel J Caslake; Heather M Murray; James Shepherd; Gerard J Blauw; Michael B. Murphy; E L E M Bollen; Brendan M Buckley; Stuart M Cobbe; Ian Ford; Allan Gaw; Michael Hyland; J Wouter Jukema; Adriaan M Kamper; Peter W Macfarlane; Jelle Jolles; Ivan J Perry; Brian J Sweeney; Cillian Twomey
Association between apolipoprotein E4 and cognitive decline in elderly adults.
Journal of the American Geriatrics Society 2007;55(11):1777-85.
2007: S Trompet; Douwe Pons; Anton J M de Craen; P Eline Slagboom; James Shepherd; Gerard J Blauw; Michael B. Murphy; Stuart M Cobbe; E L E M Bollen; Brendan M Buckley; Ian Ford; Michael Hyland; Allan Gaw; Peter W Macfarlane; Chris J Packard; John Norrie; Ivan J Perry; David J Stott; Brian J Sweeney; Cillian Twomey; Rudi G J Westendorp; J Wouter Jukema
Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study.
Annals of the New York Academy of Sciences 2007;1100():189-98.
2007: Naveed Sattar; Heather M Murray; Alex McConnachie; Gerard J Blauw; E L E M Bollen; Brendan M Buckley; Stuart M Cobbe; Ian Ford; Allan Gaw; Michael Hyland; J Wouter Jukema; Adriaan M Kamper; Peter W Macfarlane; Michael B. Murphy; Chris J Packard; Ivan J Perry; David J Stott; Brian J Sweeney; Cillian Twomey; Rudi G J Westendorp; James Shepherd
C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).
Circulation 2007;115(8):981-9.
2005: Chris J Packard; Ian Ford; Michele Robertson; James Shepherd; Gerard J Blauw; Michael B. Murphy; E L E M Bollen; Brendan M Buckley; Stuart M Cobbe; Allan Gaw; Michael Hyland; J Wouter Jukema; Adriaan M Kamper; Peter W Macfarlane; Ivan J Perry; David J Stott; Brian J Sweeney; Cillian Twomey; Rudi G J Westendorp
Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).
Circulation 2005;112(20):3058-65.
2002: James Shepherd; Gerard J Blauw; Michael B. Murphy; E L E M Bollen; Brendan M Buckley; Stuart M Cobbe; Ian Ford; Allan Gaw; Michael Hyland; J Wouter Jukema; Adriaan M Kamper; Peter W Macfarlane; A Edo Meinders; John Norrie; Chris J Packard; Ivan J Perry; David J Stott; Brian J Sweeney; Cillian Twomey; Rudi G J Westendorp
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.
Lancet 2002;360(9346):1623-30.
2002: Peter Houx; James Shepherd; Gerard J Blauw; Michael B. Murphy; Ian Ford; E L E M Bollen; Brendan M Buckley; David J Stott; W Jukema; Michael Hyland; Allan Gaw; John Norrie; Adriaan M Kamper; Ivan J Perry; Peter W Macfarlane; A Edo Meinders; Brian J Sweeney; Chris J Packard; Cillian Twomey; Stuart M Cobbe; Rudi G J Westendorp
Testing cognitive function in elderly populations: the PROSPER study. PROspective Study of Pravastatin in the Elderly at Risk.
Journal of neurology, neurosurgery, and psychiatry 2002;73(4):385-9.
2000: Niall Colwell; Brendan M Buckley; Michael B. Murphy
Unstable angina pectoris.
The New England journal of medicine 2000;342(22):1676-7; author reply 1678.
1999: James Shepherd; Gerard J Blauw; Michael B. Murphy; Stuart M Cobbe; E L E M Bollen; Brendan M Buckley; Ian Ford; J Wouter Jukema; Michael Hyland; Allan Gaw; A Margot Lagaay; Ivan J Perry; Peter W Macfarlane; A Edo Meinders; Brian J Sweeney; Chris J Packard; Rudi G J Westendorp; Cillian Twomey; David J Stott
The design of a prospective study of Pravastatin in the Elderly at Risk (PROSPER). PROSPER Study Group. PROspective Study of Pravastatin in the Elderly at Risk.
The American journal of cardiology 1999;84(10):1192-7.