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timothy hla

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
15
Liu, Catherine
15
Thangada, Shobha
13
Lee, Menq-Jer
10
Maciag, Thomas
10
Paik, Ji-Hye
9
Proia, Richard
9
Ristimäki, Ari
9
Chae, Sung-Suk
9
ancellin, nicolas
8
Wu, Ming-Tao
7
Kluk, Michael
7
Narko, Kirsi
6
Kohno, M
6
Venkataraman, Krishnan
6
Trifan, Ovidiu

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Publications

TOP 3
Skoura Athanasia; Hla Timothy
Regulation of vascular physiology and pathology by the S1P2 receptor subtype.
Li Mei-Hong; Sanchez Teresa; Yamase Harold; Hla Timothy; Oo Myat Lin; Pappalardo Anna; Lynch Kevin R; Lin Chen-Yong; Ferrer Fernando
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor.
Ghosh Mallika; Ai Youxi; Narko Kirsi; Wang Zhenglong; Peters Jeffrey M; Hla Timothy
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

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All Publications

2009: Skoura Athanasia; Hla Timothy
Regulation of vascular physiology and pathology by the S1P2 receptor subtype.
Cardiovascular research 2009;82(2):221-8.
2009: Li Mei-Hong; Sanchez Teresa; Yamase Harold; Hla Timothy; Oo Myat Lin; Pappalardo Anna; Lynch Kevin R; Lin Chen-Yong; Ferrer Fernando
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor.
Cancer letters 2009;276(2):171-9.
2009: Ghosh Mallika; Ai Youxi; Narko Kirsi; Wang Zhenglong; Peters Jeffrey M; Hla Timothy
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.
Prostaglandins & other lipid mediators 2009;88(3-4):97-100.
2009: Skoura Athanasia; Hla Timothy
Lysophospholipid receptors in vertebrate development, physiology, and pathology.
Journal of lipid research 2009;50 Suppl():S293-8.
2008: Li Mei-Hong; Sanchez Teresa; Pappalardo Anna; Lynch Kevin R; Hla Timothy; Ferrer Fernando
Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2.
Molecular cancer research : MCR 2008;6(10):1649-56.
2008: Estrada Rosendo; Zeng Qun; Lu Hongwei; Sarojini Harshini; Lee Jen-Fu; Mathis Steven P; Sanchez Teresa; Wang Eugenia; Kontos Christopher D; Lin Chen-Yong; Hla Timothy; Haribabu Bodduluri; Lee Menq-Jer
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
The Journal of biological chemistry 2008;283(44):30363-75.
2008: Hla Timothy; Venkataraman Krishnan; Michaud Jason
The vascular S1P gradient-cellular sources and biological significance.
Biochimica et biophysica acta 2008;1781(9):477-82.
2008: Venkataraman Krishnan; Lee Yong-Moon; Michaud Jason; Thangada Shobha; Ai Youxi; Bonkovsky Herbert L; Parikh Nehal S; Habrukowich Cheryl; Hla Timothy
Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.
Circulation research 2008;102(6):669-76.
2007: Lee Yong-Moon; Venkataraman Krishnan; Hwang Sun-Il; Han David K; Hla Timothy
A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC).
Prostaglandins & other lipid mediators 2007;84(3-4):154-62.
2007: Ghosh Mallika; Wang Haibin; Ai Youxi; Romeo Elisa; Luyendyk James P; Peters Jeffrey M; Mackman Nigel; Dey Sudhansu K; Hla Timothy
COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation.
The Journal of experimental medicine 2007;204(9):2053-61.
2007: Skoura Athanasia; Sanchez Teresa; Claffey Kevin; Mandala Suzanne M; Proia Richard L; Hla Timothy
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.
The Journal of clinical investigation 2007;117(9):2506-16.
2007: Sanchez Teresa; Skoura Athanasia; Wu Ming Tao; Casserly Brian; Harrington Elizabeth O; Hla Timothy
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1312-8.
2007: Kono Mari; Belyantseva Inna A; Skoura Athanasia; Frolenkov Gregory I; Starost Matthew F; Dreier Jennifer L; Lidington Darcy; Bolz Steffen-Sebastian; Friedman Thomas B; Hla Timothy; Proia Richard L
Deafness and stria vascularis defects in S1P2 receptor-null mice.
The Journal of biological chemistry 2007;282(14):10690-6.
2007: Oo Myat Lin; Thangada Shobha; Wu Ming-Tao; Liu Catherine H; Macdonald Timothy L; Lynch Kevin R; Lin Chen-Yong; Hla Timothy
Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor.
The Journal of biological chemistry 2007;282(12):9082-9.
2007: Gonzalez-Cabrera Pedro J; Hla Timothy; Rosen Hugh
Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.
The Journal of biological chemistry 2007;282(10):7254-64.
2007: Hla Timothy; Feinmark Steven J
A festschrift for J. Martyn Bailey, a biochemist extraordinaire.
Prostaglandins & other lipid mediators 2007;83(1-2):154-7.
2006: Kohno Masataka; Momoi Michiko; Oo Myat Lin; Paik Ji-Hye; Lee Yong-Moon; Venkataraman Krishnan; Ai Youxi; Ristimaki Ari P; Fyrst Henrik; Sano Hajime; Rosenberg Daniel; Saba Julie D; Proia Richard L; Hla Timothy
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation.
Molecular and cellular biology 2006;26(19):7211-23.
2006: Michaud Jason; Kohno Masataka; Proia Richard L; Hla Timothy
Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice.
FEBS letters 2006;580(19):4607-12.
2006: Venkataraman Krishnan; Thangada Shobha; Michaud Jason; Oo Myat Lin; Ai Youxi; Lee Yong-Moon; Wu Mingtao; Parikh Nehal S; Khan Faraz; Proia Richard L; Hla Timothy
Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.
The Biochemical journal 2006;397(3):461-71.
2006: Thompson Brian; Ancellin Nicolas; Fernandez Salvador M; Hla Tim; Sha'afi Ramadan I
Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell.
Prostaglandins & other lipid mediators 2006;80(1-2):15-27.
2006: Kitano Masayasu; Hla Timothy; Sekiguchi Masahiro; Kawahito Yutaka; Yoshimura Rikio; Miyazawa Keiji; Iwasaki Tsuyoshi; Sano Hajime; Saba Julie D; Tam Yuen Yee
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression.
Arthritis and rheumatism 2006;54(3):742-53.
2005: Hla Timothy
Immunology. Dietary factors and immunological consequences.
Science (New York, N.Y.) 2005;309(5741):1682-3.
2005: Hla Timothy
Genomic insights into mediator lipidomics.
Prostaglandins & other lipid mediators 2005;77(1-4):197-209.
2005: Jo Euijung; Sanna M Germana; Gonzalez-Cabrera Pedro J; Thangada Shobha; Tigyi Gabor; Osborne Daniel A; Hla Timothy; Parrill Abby L; Rosen Hugh
S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate.
Chemistry & biology 2005;12(6):703-15.
2005: Chang Sung-Hee; Ai Youxi; Breyer Richard M; Lane Timothy F; Hla Timothy
The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia.
Cancer research 2005;65(11):4496-9.
2005: Narko Kirsi; Zweifel Ben; Trifan Ovidiu; Ristimäki Ari; Lane Timothy F; Hla Timothy
COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice.
Prostaglandins & other lipid mediators 2005;76(1-4):86-94.
2005: Chang Sung-Hee; Liu Catherine H; Wu Ming-Tao; Hla Timothy
Regulation of vascular endothelial cell growth factor expression in mouse mammary tumor cells by the EP2 subtype of the prostaglandin E2 receptor.
Prostaglandins & other lipid mediators 2005;76(1-4):48-58.
2005: Heinonen Mira; Bono Petri; Narko Kirsi; Chang Sung-Hee; Lundin Johan; Joensuu Heikki; Furneaux Henry; Hla Timothy; Haglund Caj; Ristimäki Ari
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.
Cancer research 2005;65(6):2157-61.
2005: Sanchez Teresa; Thangada Shobha; Wu Ming-Tao; Kontos Christopher D; Wu Dianqing; Wu Hong; Hla Timothy
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4312-7.
2005: Chae Sung-Suk; Hla Timothy
Inhibition of gene expression in vivo using multiplex siRNA.
Methods in molecular biology (Clifton, N.J.) 2005;309():197-203.
2004: Chae Sung-Suk; Paik Ji-Hye; Furneaux Henry; Hla Timothy
Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference.
The Journal of clinical investigation 2004;114(8):1082-9.
2004: Paik Ji-Hye; Skoura Athanasia; Chae Sung-Suk; Cowan Ann E; Han David K; Proia Richard L; Hla Timothy
Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization.
Genes & development 2004;18(19):2392-403.
2004: Hla Timothy
Physiological and pathological actions of sphingosine 1-phosphate.
Seminars in cell & developmental biology 2004;15(5):513-20.
2004: Sanchez Teresa; Hla Timothy
Structural and functional characteristics of S1P receptors.
Journal of cellular biochemistry 2004;92(5):913-22.
2004: Chae Sung-Suk; Paik Ji-Hye; Allende Maria L; Proia Richard L; Hla Timothy
Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/VEGF axis.
Developmental biology 2004;268(2):441-7.
2004: Chae Sung-Suk; Proia Richard L; Hla Timothy
Constitutive expression of the S1P1 receptor in adult tissues.
Prostaglandins & other lipid mediators 2004;73(1-2):141-50.
2004: Chang Sung-Hee; Liu Catherine H; Conway Rebecca; Han David K; Nithipatikom Kasem; Trifan Ovidiu C; Lane Timothy F; Hla Timothy
Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):591-6.
2003: Erkinheimo Tiina-Liisa; Lassus Heini; Sivula Anna; Sengupta Sibani; Furneaux Henry; Hla Timothy; Haglund Caj; Butzow Ralf; Ristimäki Ari
Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.
Cancer research 2003;63(22):7591-4.
2003: Sanchez Teresa; Estrada-Hernandez Tatiana; Paik Ji-Hye; Wu Ming-Tao; Venkataraman Krishnan; Brinkmann Volker; Claffey Kevin; Hla Timothy
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.
The Journal of biological chemistry 2003;278(47):47281-90.
2003: Sengupta Sibani; Jang Byeong-Churl; Wu Ming-Tao; Paik Ji-Hye; Furneaux Henry; Hla Timothy
The RNA-binding protein HuR regulates the expression of cyclooxygenase-2.
The Journal of biological chemistry 2003;278(27):25227-33.
2003: Donohue Patrick J; Richards Christine M; Brown Sharron A N; Hanscom Heather N; Buschman John; Thangada Shobha; Hla Timothy; Williams Mark S; Winkles Jeffrey A
TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(4):594-600.
2003: Kluk Michael J; Colmont Chantal; Wu Ming-Tao; Hla Timothy
Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells.
FEBS letters 2003;533(1-3):25-8.
2003: Jang Byeong-Churl; Muñoz-Najar Ursula; Paik Ji-Hye; Claffey Kevin; Yoshida Minoru; Hla Timothy
Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression.
The Journal of biological chemistry 2003;278(5):2773-6.
2003: Ozaki Harunobu; Hla Timothy; Lee Menq-Jer
Sphingosine-1-phosphate signaling in endothelial activation.
Journal of atherosclerosis and thrombosis 2003;10(3):125-31.
2002: Bishop-Bailey David; Hla Timothy; Warner Timothy D
Intimal smooth muscle cells as a target for peroxisome proliferator-activated receptor-gamma ligand therapy.
Circulation research 2002;91(3):210-7.
2002: Kluk Michael J; Hla Timothy
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors.
Biochimica et biophysica acta 2002;1582(1-3):72-80.
2002: Ancellin Nicolas; Colmont Chantal; Su Joseph; Li Qin; Mittereder Nanette; Chae Sung-Suk; Stefansson Steingrimur; Liau Gene; Hla Timothy
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation.
The Journal of biological chemistry 2002;277(8):6667-75.
2002: Bishop-Bailey David; Calatayud Sara; Warner Timothy D; Hla Timothy; Mitchell Jane A
Prostaglandins and the regulation of tumor growth.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2002;21(2):93-101.
2001: Hla T; Lee M J; Ancellin N; Paik J H; Kluk M J
Lysophospholipids--receptor revelations.
Science (New York, N.Y.) 2001;294(5548):1875-8.
2001: Lee M J; Thangada S; Paik J H; Sapkota G P; Ancellin N; Chae S S; Wu M; Morales-Ruiz M; Sessa W C; Alessi D R; Hla T
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis.
Molecular cell 2001;8(3):693-704.
2001: Kluk M J; Hla T
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
Circulation research 2001;89(6):496-502.
2001: Inoue K; Kawahito Y; Tsubouchi Y; Yamada R; Kohno M; Hosokawa Y; Katoh D; Bishop-Bailey D; Hla T; Sano H
Expression of peroxisome proliferator-activated receptor (PPAR)-gamma in human lung cancer.
Anticancer research 2001;21(4A):2471-6.
2001: Tsubouchi Y; Kawahito Y; Kohno M; Inoue K; Hla T; Sano H
Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.
Biochemical and biophysical research communications 2001;283(4):750-5.
2001: Liu C H; Chang S H; Narko K; Trifan O C; Wu M T; Smith E; Haudenschild C; Lane T F; Hla T
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice.
The Journal of biological chemistry 2001;276(21):18563-9.
2001: Hla T
Sphingosine 1-phosphate receptors.
Prostaglandins & other lipid mediators 2001;64(1-4):135-42.
2001: Paik J H; Chae Ss; Lee M J; Thangada S; Hla T
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins.
The Journal of biological chemistry 2001;276(15):11830-7.
2001: Casibang M; Purdom S; Jakowlew S; Neckers L; Zia F; Ben-Av P; Hla T; You L; Jablons D M; Moody T W
Prostaglandin E2 and vasoactive intestinal peptide increase vascular endothelial cell growth factor mRNAs in lung cancer cells.
Lung cancer (Amsterdam, Netherlands) 2001;31(2-3):203-12.
2000: Jang B C; Sanchez T; Schaefers H J; Trifan O C; Liu C H; Creminon C; Huang C K; Hla T
Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase.
The Journal of biological chemistry 2000;275(50):39507-15.
2000: Liu Y; Wada R; Yamashita T; Mi Y; Deng C X; Hobson J P; Rosenfeldt H M; Nava V E; Chae S S; Lee M J; Liu C H; Hla T; Spiegel S; Proia R L
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.
The Journal of clinical investigation 2000;106(8):951-61.
2000: Bishop-Bailey D; Hla T; Warner T D
Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line.
British journal of pharmacology 2000;131(4):651-4.
2000: Kawahito Y; Kondo M; Tsubouchi Y; Hashiramoto A; Bishop-Bailey D; Inoue K; Kohno M; Yamada R; Hla T; Sano H
15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats.
The Journal of clinical investigation 2000;106(2):189-97.
2000: Ancellin N; Hla T
Switching intracellular signaling pathways to study sphingosine 1-phosphate receptors.
Annals of the New York Academy of Sciences 2000;905():260-2.
2000: Hla T; Lee M J; Ancellin N; Thangada S; Liu C H; Kluk M; Chae S S; Wu M T
Sphingosine-1-phosphate signaling via the EDG-1 family of G-protein-coupled receptors.
Annals of the New York Academy of Sciences 2000;905():16-24.
2000: Tsubouchi Y; Sano H; Kawahito Y; Mukai S; Yamada R; Kohno M; Inoue K; Hla T; Kondo M
Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis.
Biochemical and biophysical research communications 2000;270(2):400-5.
2000: Yamada R; Sano H; Hla T; Hashiramoto A; Kawahito Y; Mukai S; Kohno M; Tsubouchi Y; Inoue M; Komatsu A; Inoue K; Kondo M
Selective inhibition of cyclooxygenase-2 with antisense oligodeoxynucleotide restricts induction of rat adjuvant-induced arthritis.
Biochemical and biophysical research communications 2000;269(2):415-21.
1999: Yamada R; Sano H; Hla T; Hashiramoto A; Fukui W; Miyazaki S; Kohno M; Tsubouchi Y; Kusaka Y; Kondo M
Auranofin inhibits interleukin-1beta-induced transcript of cyclooxygenase-2 on cultured human synoviocytes.
European journal of pharmacology 1999;385(1):71-9.
1999: Trifan O C; Smith R M; Thompson B D; Hla T
Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism.
The Journal of biological chemistry 1999;274(48):34141-7.
1999: Lee M J; Thangada S; Claffey K P; Ancellin N; Liu C H; Kluk M; Volpi M; Sha'afi R I; Hla T
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate.
Cell 1999;99(3):301-12.
1999: Hla T; Lee M J; Ancellin N; Liu C H; Thangada S; Thompson B D; Kluk M
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
Biochemical pharmacology 1999;58(2):201-7.
1999: Ancellin N; Hla T
Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5.
The Journal of biological chemistry 1999;274(27):18997-9002.
1999: Bishop-Bailey D; Hla T
Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2.
The Journal of biological chemistry 1999;274(24):17042-8.
1999: Hla T; Bishop-Bailey D; Liu C H; Schaefers H J; Trifan O C
Cyclooxygenase-1 and -2 isoenzymes.
The international journal of biochemistry & cell biology 1999;31(5):551-7.
1999: Liu C H; Thangada S; Lee M J; Van Brocklyn J R; Spiegel S; Hla T
Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1.
Molecular biology of the cell 1999;10(4):1179-90.
1999: Bishop-Bailey D; Hla T; Mitchell J A
Cyclo-oxygenase-2 in vascular smooth muscle.
International journal of molecular medicine 1999;3(1):41-8.
1998: Lee M J; Thangada S; Liu C H; Thompson B D; Hla T
Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist.
The Journal of biological chemistry 1998;273(34):22105-12.
1998: Van Brocklyn J R; Lee M J; Menzeleev R; Olivera A; Edsall L; Cuvillier O; Thomas D M; Coopman P J; Thangada S; Liu C H; Hla T; Spiegel S
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival.
The Journal of cell biology 1998;142(1):229-40.
1998: Lee M J; Van Brocklyn J R; Thangada S; Liu C H; Hand A R; Menzeleev R; Spiegel S; Hla T
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1.
Science (New York, N.Y.) 1998;279(5356):1552-5.
1998: Gou Q; Liu C H; Ben-Av P; Hla T
Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 3'-untranslated region.
Biochemical and biophysical research communications 1998;242(3):508-12.
1997: Hla T; Zimrin A B; Evans M; Ballas K; Maciag T
The immediate-early gene product MAD-3/EDG-3/IkappaB alpha is an endogenous modulator of fibroblast growth factor-1 (FGF-1) dependent human endothelial cell growth.
FEBS letters 1997;414(2):419-24.
1997: Narko K; Ristimäki A; MacPhee M; Smith E; Haudenschild C C; Hla T
Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression.
The Journal of biological chemistry 1997;272(34):21455-60.
1997: Liu C H; Hla T
The mouse gene for the inducible G-protein-coupled receptor edg-1.
Genomics 1997;43(1):15-24.
1996: Ristimäki A; Narko K; Hla T
Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation.
The Biochemical journal 1996;318 ( Pt 1)():325-31.
1996: Lee M J; Evans M; Hla T
The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway.
The Journal of biological chemistry 1996;271(19):11272-9.
1995: Ben-Av P; Crofford L J; Wilder R L; Hla T
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis.
FEBS letters 1995;372(1):83-7.
1995: Hla T; Jackson A Q; Appleby S B; Maciag T
Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells.
Biochimica et biophysica acta 1995;1260(2):227-9.
1994: Appleby S B; Ristimäki A; Neilson K; Narko K; Hla T
Structure of the human cyclo-oxygenase-2 gene.
The Biochemical journal 1994;302 ( Pt 3)():723-7.
1994: Ristimäki A; Garfinkel S; Wessendorf J; Maciag T; Hla T
Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.
The Journal of biological chemistry 1994;269(16):11769-75.
1994: Crofford L J; Wilder R L; Ristimäki A P; Sano H; Remmers E F; Epps H R; Hla T
Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.
The Journal of clinical investigation 1994;93(3):1095-101.
1993: Hla T; Ristimäki A; Appleby S; Barriocanal J G
Cyclooxygenase gene expression in inflammation and angiogenesis.
Annals of the New York Academy of Sciences 1993;696():197-204.
1993: Sano H; Engleka K; Mathern P; Hla T; Crofford L J; Remmers E F; Jelsema C L; Goldmuntz E; Maciag T; Wilder R L
Coexpression of phosphotyrosine-containing proteins, platelet-derived growth factor-B, and fibroblast growth factor-1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis.
The Journal of clinical investigation 1993;91(2):553-65.
1992: Hla T; Neilson K
Human cyclooxygenase-2 cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7384-8.
1992: Sano H; Hla T; Maier J A; Crofford L J; Case J P; Maciag T; Wilder R L
In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis.
The Journal of clinical investigation 1992;89(1):97-108.
1991: Hla T; Maciag T
Cyclooxygenase gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells.
The Journal of biological chemistry 1991;266(35):24059-63.
1991: Siegall C B; Epstein S; Speir E; Hla T; Forough R; Maciag T; Fitzgerald D J; Pastan I
Cytotoxic activity of chimeric proteins composed of acidic fibroblast growth factor and Pseudomonas exotoxin on a variety of cell types.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(13):2843-9.
1991: Remmers E F; Sano H; Lafyatis R; Case J P; Kumkumian G K; Hla T; Maciag T; Wilder R L
Production of platelet derived growth factor B chain (PDGF-B/c-sis) mRNA and immunoreactive PDGF B-like polypeptide by rheumatoid synovium: coexpression with heparin binding acidic fibroblast growth factor-1.
The Journal of rheumatology 1991;18(1):7-13.
1990: Imamura T; Engleka K; Zhan X; Tokita Y; Forough R; Roeder D; Jackson A; Maier J A; Hla T; Maciag T
Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence.
Science (New York, N.Y.) 1990;249(4976):1567-70.
1990: Maier J A; Hla T; Maciag T
Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.
The Journal of biological chemistry 1990;265(19):10805-8.
1990: Hla T; Maciag T
An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors.
The Journal of biological chemistry 1990;265(16):9308-13.
1988: Siegall C B; Hla T T; Kumar A
Reconstituted U1 small nuclear ribonucleoprotein complex restores 5' splice site cleavage activity.
Biochemical and biophysical research communications 1988;154(3):1010-7.

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