Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Friedrich Grimminger
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Disorders
Anatomy
Living Beings
Chemicals & Drugs
Physiology
Procedures
Sign-in to see full Profile
Network (preview)
264
Seeger, Werner
105
Ghofrani, Hossein
94
Weissmann, Norbert
89
Schermuly, Ralph Theo
74
Walmrath, Dieter
49
Rose, Frank
41
Olschewski, Horst
40
Mayer, Konstantin
38
Sibelius, Ulf
28
Günther, Andreas
26
Voswinckel, Robert
25
Hänze, Jörg
22
Fink, Ludger
22
Schütte, Hartwig
20
Rosseau, Simone
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Friedrich Grimminger (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Kolosionek Ewa; Savai Rajkumar; Ghofrani Hossein Ardeschir; Weissmann Norbert; Guenther Andreas; Grimminger Friedrich; Seeger Werner; Banat Gamal Andre; Schermuly Ralph Theo; Pullamsetti Soni Savai
Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.
Molecular biology of the cell 2009;20(22):4751-65.
-
2009: Ketabchi Farzaneh; Egemnazarov Bakytbek; Schermuly Ralph T; Ghofrani Hossein A; Seeger Werner; Grimminger Friedrich; Shid-Moosavi Mostafa; Dehghani Gholam A; Weissmann Norbert; Sommer Natascha
Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction.
American journal of physiology. Lung cellular and molecular physiology 2009;297(5):L977-83.
-
2009: Grandel Ulrich; Heygster Diana; Sibelius Ulf; Fink Ludger; Sigel Stefanie; Seeger Werner; Grimminger Friedrich; Hattar Katja
Amplification of lipopolysaccharide-induced cytokine synthesis in non-small cell lung cancer/neutrophil cocultures.
Molecular cancer research : MCR 2009;7(10):1729-35.
-
2009: Weissmann Norbert; Hackemack Sascha; Dahal Bhola Kumar; Pullamsetti Soni Savai; Savai Rajkumar; Mittal Manish; Fuchs Beate; Medebach Thomas; Dumitrascu Rio; Eickels Martin van; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.
American journal of physiology. Lung cellular and molecular physiology 2009;297(4):L658-65.
-
2009: Voswinckel R; Reichenberger F; Gall H; Seeger W; Grimminger F; Ghofrani H A
[Therapy of pulmonary arterial hypertension]
Der Internist 2009;50(9):1101-2, 1104-9.
-
2009: Cakarova Lidija; Marsh Leigh M; Wilhelm Jochen; Mayer Konstantin; Grimminger Friedrich; Seeger Werner; Lohmeyer Juergen; Herold Susanne
Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.
American journal of respiratory and critical care medicine 2009;180(6):521-32.
-
2009: Markart P; Ghofrani H A; Grimminger F; Günther A
[Pulmonary hypertension in COPD and interstitial lung diseases]
Deutsche medizinische Wochenschrift (1946) 2009;134 Suppl 5():S164-6.
-
2009: Roth Markus; Rupp Markus; Hofmann Simone; Mittal Manish; Fuchs Beate; Sommer Natascha; Parajuli Nirmal; Quanz Karin; Schubert Dominic; Dony Eva; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Sausbier Ulrike; Rutschmann Katrin; Wilhelm Sarah; Seeger Werner; Ruth Peter; Grimminger Friedrich; Sausbier Matthias; Weissmann Norbert
Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia.
American journal of respiratory and critical care medicine 2009;180(4):353-64.
-
2009: Ghofrani Hossein A; Barst Robyn J; Benza Raymond L; Champion Hunter C; Fagan Karen A; Grimminger Friedrich; Humbert Marc; Simonneau Gérald; Stewart Duncan J; Ventura Carlo; Rubin Lewis J
Future perspectives for the treatment of pulmonary arterial hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S108-17.
-
2009: Hassoun Paul M; Mouthon Luc; Barberà Joan A; Eddahibi Saadia; Flores Sonia C; Grimminger Friedrich; Jones Peter Lloyd; Maitland Michael L; Michelakis Evangelos D; Morrell Nicholas W; Newman John H; Rabinovitch Marlene; Schermuly Ralph; Stenmark Kurt R; Voelkel Norbert F; Yuan Jason X-J; Humbert Marc
Inflammation, growth factors, and pulmonary vascular remodeling.
Journal of the American College of Cardiology 2009;54(1 Suppl):S10-9.
-
2009: Grandel Ulrich; Bennemann Ulrich; Buerke Michael; Hattar Katja; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Staphylococcus aureus alpha-toxin and Escherichia coli hemolysin impair cardiac regional perfusion and contractile function by activating myocardial eicosanoid metabolism in isolated rat hearts.
Critical care medicine 2009;37(6):2025-32.
-
2009: Laumanns Isabel P; Fink Ludger; Wilhelm Jochen; Wolff Jens-C; Mitnacht-Kraus Rita; Graef-Hoechst Sabine; Stein Maria M; Bohle Rainer M; Klepetko Walter; Hoda Mir A R; Schermuly Ralph T; Grimminger Friedrich; Seeger Werner; Voswinckel Robert
The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension.
American journal of respiratory cell and molecular biology 2009;40(6):683-91.
-
2009: Yu Ying; Keller Steve H; Remillard Carmelle V; Safrina Olga; Nicholson Ann; Zhang Shenyuan L; Jiang Weihua; Vangala Nivruthi; Landsberg Judd W; Wang Jian-Ying; Thistlethwaite Patricia A; Channick Richard N; Robbins Ivan M; Loyd James E; Ghofrani Hossein A; Grimminger Friedrich; Schermuly Ralph T; Cahalan Michael D; Rubin Lewis J; Yuan Jason X-J
A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension.
Circulation 2009;119(17):2313-22.
-
2009: Grimminger F; Weimann G; Frey R; Voswinckel R; Thamm M; Bölkow D; Weissmann N; Mück W; Unger S; Wensing G; Schermuly R T; Ghofrani H A
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(4):785-92.
-
2009: Woyda K; Koebrich S; Reiss I; Rudloff S; Pullamsetti S S; Rühlmann A; Weissmann N; Ghofrani H A; Günther A; Seeger W; Grimminger F; Morty R E; Schermuly R T
Inhibition of phosphodiesterase 4 enhances lung alveolarisation in neonatal mice exposed to hyperoxia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(4):861-70.
-
2009: Egemnazarov Bakytbek; Sydykov Akylbek; Schermuly Ralph T; Weissmann Norbert; Stasch Johannes-Peter; Sarybaev Akpai S; Seeger Werner; Grimminger Friedrich; Ghofrani Hossein A
Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury.
American journal of physiology. Lung cellular and molecular physiology 2009;296(3):L462-9.
-
2009: Kamlah F; Eul B G; Li S; Lang N; Marsh L M; Seeger W; Grimminger F; Rose F; Hänze J
Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model.
Cancer gene therapy 2009;16(3):195-205.
-
2009: Voswinckel Robert; Reichenberger Frank; Gall Henning; Schmehl Thomas; Gessler Tobias; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Seeger Werner; Ghofrani Hossein A; Olschewski Horst
Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension.
Pulmonary pharmacology & therapeutics 2009;22(1):50-6.
-
2008: Sommer N; Dietrich A; Schermuly R T; Ghofrani H A; Gudermann T; Schulz R; Seeger W; Grimminger F; Weissmann N
Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(6):1639-51.
-
2008: Klein Martina; Schermuly Ralph T; Ellinghaus Peter; Milting Hendrik; Riedl Bernd; Nikolova Sevdalina; Pullamsetti Soni S; Weissmann Norbert; Dony Eva; Savai Rajkumar; Ghofrani Hossein A; Grimminger Friedrich; Busch Andreas E; Schäfer Stefan
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.
Circulation 2008;118(20):2081-90.
-
2008: Butrous Ghazwan; Ghofrani Hossein Ardeschir; Grimminger Friedrich
Pulmonary vascular disease in the developing world.
Circulation 2008;118(17):1758-66.
-
2008: Hoeper M M; Ghofrani H A; Grimminger F; Rosenkranz S
[Dana Point: what is new in the treatment of pulmonary hypertension?]
Deutsche medizinische Wochenschrift (1946) 2008;133 Suppl 6():S191-5.
-
2008: Schermuly R; Grimminger F
[Update in basic research in the therapy of pulmonary arterial hypertension]
Deutsche medizinische Wochenschrift (1946) 2008;133 Suppl 6():S170-2.
-
2008: Kiss Ladislau; Bier Jens; Röder Yasmin; Weissmann Norbert; Grimminger Friedrich; Seeger Werner
Direct and simultaneous profiling of epoxyeicosatrienoic acid enantiomers by capillary tandem column chiral-phase liquid chromatography with dual online photodiode array and tandem mass spectrometric detection.
Analytical and bioanalytical chemistry 2008;392(4):717-26.
-
2008: Voswinckel Robert; Reichenberger Frank; Enke Beate; Kreckel Andre; Krick Stefanie; Gall Henning; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Olschewski Horst; Seeger Werner; Ghofrani Hossein A
Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension.
Pulmonary pharmacology & therapeutics 2008;21(5):824-32.
-
2008: Li Shu; Tabar Sarvenaz Shafiei; Malec Viktor; Eul Bastian G; Klepetko Walter; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Rose Frank; Hänze Jörg
NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts.
Antioxidants & redox signaling 2008;10(10):1687-98.
-
2008: Schermuly R T; Stasch J-P; Pullamsetti S S; Middendorff R; Müller D; Schlüter K-D; Dingendorf A; Hackemack S; Kolosionek E; Kaulen C; Dumitrascu R; Weissmann N; Mittendorf J; Klepetko W; Seeger W; Ghofrani H A; Grimminger F
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(4):881-91.
-
2008: Kwapiszewska Grazyna; Wygrecka Malgorzata; Marsh Leigh M; Schmitt Sigrid; Trösser Roger; Wilhelm Jochen; Helmus Katja; Eul Bastian; Zakrzewicz Anna; Ghofrani Hossein A; Schermuly Ralph T; Bohle Rainer M; Grimminger Friedrich; Seeger Werner; Eickelberg Oliver; Fink Ludger; Weissmann Norbert
Fhl-1, a new key protein in pulmonary hypertension.
Circulation 2008;118(11):1183-94.
-
2008: Ahlbrecht Katrin; Schmitz Judith; Seay Ulrike; Schwarz Christine; Mittnacht-Kraus Rita; Gaumann Andreas; Haberberger Rainer V; Herold Susanne; Breier Georg; Grimminger Friedrich; Seeger Werner; Voswinckel Robert
Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development.
American journal of respiratory cell and molecular biology 2008;39(2):163-70.
-
2008: Wilkins M R; Wharton J; Grimminger F; Ghofrani H A
Phosphodiesterase inhibitors for the treatment of pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(1):198-209.
-
2008: Lai Ying-Ju; Pullamsetti Soni Savai; Dony Eva; Weissmann Norbert; Butrous Ghazwan; Banat Gamal-Andre; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension.
American journal of respiratory and critical care medicine 2008;178(2):188-96.
-
2008: Vadász István; Schermuly Ralph T; Ghofrani Hossein A; Rummel Sebastian; Wehner Susan; Mühldorfer Inge; Schäfer Klaus P; Seeger Werner; Morty Rory E; Grimminger Friedrich; Weissmann Norbert
The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs.
Critical care medicine 2008;36(5):1543-50.
-
2008: Buerke Ute; Carter Justin M; Schlitt Axel; Russ Martin; Schmidt Hendrik; Sibelius Ulf; Grandel Ulrich; Grimminger Friedrich; Seeger Werner; Mueller-Werdan Ursula; Werdan Karl; Buerke Michael
Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy.
Shock (Augusta, Ga.) 2008;29(4):497-503.
-
2008: Dony E; Lai Y-J; Dumitrascu R; Pullamsetti S S; Savai R; Ghofrani H A; Weissmann N; Schudt C; Flockerzi D; Seeger W; Grimminger F; Schermuly R T
Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;31(3):599-610.
-
2008: Kiss Ladislau; Röder Yasmin; Bier Jens; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection.
Analytical and bioanalytical chemistry 2008;390(2):697-714.
-
2008: Kitowska Kamila; Zakrzewicz Dariusz; Königshoff Melanie; Chrobak Izabella; Grimminger Friedrich; Seeger Werner; Bulau Patrick; Eickelberg Oliver
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2008;294(1):L34-45.
-
2008: Kirsch Mark; Kemp-Harper Barbara; Weissmann Norbert; Grimminger Friedrich; Schmidt Harald H H W
Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):30-40.
-
2008: Dumitrascu Rio; Koebrich Silke; Dony Eva; Weissmann Norbert; Savai Rajkumar; Pullamsetti Soni S; Ghofrani Hossein A; Samidurai Arun; Traupe Horst; Seeger Werner; Grimminger Friedrich; Schermuly Ralph T
Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.
BMC pulmonary medicine 2008;8():25.
-
2007: Reichenberger Frank; Kohstall Markus G; Seeger Timon; Olschewski Horst; Grimminger Friedrich; Seeger Werner; Ghofrani Hossein A
Effect of sildenafil on hypoxia-induced changes in pulmonary circulation and right ventricular function.
Respiratory physiology & neurobiology 2007;159(2):196-201.
-
2007: Reichenberger F; Voswinckel R; Enke B; Rutsch M; El Fechtali E; Schmehl T; Olschewski H; Schermuly R; Weissmann N; Ghofrani H A; Grimminger F; Mayer E; Seeger W
Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;30(5):922-7.
-
2007: Weissmann Norbert; Gerigk Boris; Kocer Ozlem; Nollen Matthias; Hackemack Sascha; Ghofrani Hossein Ardeschir; Schermuly Ralph Theo; Butrous Ghazwan; Schulz Andreas; Roth Markus; Seeger Werner; Grimminger Friedrich
Hypoxia-induced pulmonary hypertension: different impact of iloprost, sildenafil, and nitric oxide.
Respiratory medicine 2007;101(10):2125-32.
-
2007: Mittal Manish; Roth Markus; König Peter; Hofmann Simone; Dony Eva; Goyal Parag; Selbitz Anne-Christin; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Kwapiszewska Grazyna; Kummer Wolfgang; Klepetko Walter; Hoda Mir Ali Reza; Fink Ludger; Hänze Jörg; Seeger Werner; Grimminger Friedrich; Schmidt Harald H H W; Weissmann Norbert
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
Circulation research 2007;101(3):258-67.
-
2007: Dietrich Alexander; Kalwa Hermann; Fuchs Beate; Grimminger Friedrich; Weissmann Norbert; Gudermann Thomas
In vivo TRPC functions in the cardiopulmonary vasculature.
Cell calcium 2007;42(2):233-44.
-
2007: Savai Rajkumar; Schermuly Ralph Theo; Pullamsetti Soni Savai; Schneider Michael; Greschus Susanne; Ghofrani Hossein Ardeschir; Traupe Horst; Grimminger Friedrich; Banat Gamal-Andre
A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells.
Cancer research 2007;67(11):5443-53.
-
2007: Hänze Jörg; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Rose Frank
Cellular and molecular mechanisms of hypoxia-inducible factor driven vascular remodeling.
Thrombosis and haemostasis 2007;97(5):774-87.
-
2007: Schermuly Ralph Theo; Pullamsetti Soni Savai; Kwapiszewska Grazyna; Dumitrascu Rio; Tian Xia; Weissmann Norbert; Ghofrani Hossein Ardeschir; Kaulen Christina; Dunkern Torsten; Schudt Christian; Voswinckel Robert; Zhou Jiang; Samidurai Arun; Klepetko Walter; Paddenberg Renate; Kummer Wolfgang; Seeger Werner; Grimminger Friedrich
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Circulation 2007;115(17):2331-9.
-
2007: Günther A; Enke B; Markart P; Hammerl P; Morr H; Behr J; Stähler G; Seeger W; Grimminger F; Leconte I; Roux S; Ghofrani H-A
Safety and tolerability of bosentan in idiopathic pulmonary fibrosis: an open label study.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(4):713-9.
-
2007: Schaefer Martina Barbara; Ott Juliane; Mohr Andrea; Bi Ming Hua; Grosz Andrea; Weissmann Norbert; Ishii Satoshi; Grimminger Friedrich; Seeger Werner; Mayer Konstantin
Immunomodulation by n-3- versus n-6-rich lipid emulsions in murine acute lung injury--role of platelet-activating factor receptor.
Critical care medicine 2007;35(2):544-54.
-
2007: Bulau Patrick; Zakrzewicz Dariusz; Kitowska Kamila; Leiper James; Gunther Andreas; Grimminger Friedrich; Eickelberg Oliver
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA.
American journal of physiology. Lung cellular and molecular physiology 2007;292(1):L18-24.
-
2007: Schermuly Ralph T; Pullamsetti Soni S; Breitenbach Susanne C; Weissmann Norbert; Ghofrani Hossein A; Grimminger Friedrich; Nilius Sigrid M; Schrör Karsten; Kirchrath Jutta M; Seeger Werner; Rose Frank
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs.
Respiratory research 2007;8():4.
-
2007: Rosengarten Bernhard; Hecht Mirko; Auch Dieter; Ghofrani Hossein Ardeschir; Schermuly Ralf Theo; Grimminger Friedrich; Kaps Manfred
Microcirculatory dysfunction in the brain precedes changes in evoked potentials in endotoxin-induced sepsis syndrome in rats.
Cerebrovascular diseases (Basel, Switzerland) 2007;23(2-3):140-7.
-
2006: Weissmann Norbert; Dietrich Alexander; Fuchs Beate; Kalwa Hermann; Ay Mahmut; Dumitrascu Rio; Olschewski Andrea; Storch Ursula; Mederos y Schnitzler Michael; Ghofrani Hossein Ardeschir; Schermuly Ralph Theo; Pinkenburg Olaf; Seeger Werner; Grimminger Friedrich; Gudermann Thomas
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19093-8.
-
2006: Ghofrani H A; Rosenkranz S; Grimminger F
[Future aspects of the treatment of pulmonary arterial hypertension.]
Deutsche medizinische Wochenschrift (1946) 2006;131(49 Suppl 9):S338-40.
-
2006: Ghofrani H A; Grimminger F
[Treatment of pulmonary arterial hypertension: phosphodiesterase-5 inhibitors]
Deutsche medizinische Wochenschrift (1946) 2006;131(49 Suppl 9):S311-4.
-
2006: Voswinckel Robert; Enke Beate; Reichenberger Frank; Kohstall Markus; Kreckel Andree; Krick Stefanie; Gall Henning; Gessler Tobias; Schmehl Thomas; Ghofrani Hossein A; Schermuly Ralph Theo; Grimminger Friedrich; Rubin Lewis J; Seeger Werner; Olschewski Horst
Favorable effects of inhaled treprostinil in severe pulmonary hypertension: results from randomized controlled pilot studies.
Journal of the American College of Cardiology 2006;48(8):1672-81.
-
2006: Ghofrani Hossein A; Voswinckel Robert; Reichenberger Frank; Weissmann Norbert; Schermuly Ralph T; Seeger Werner; Grimminger Friedrich
Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies.
Cardiovascular research 2006;72(1):30-40.
-
2006: Yildirim Ali O; Bulau Patrick; Zakrzewicz Dariusz; Kitowska Kamila E; Weissmann Norbert; Grimminger Friedrich; Morty Rory E; Eickelberg Oliver
Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases.
American journal of respiratory cell and molecular biology 2006;35(4):436-43.
-
2006: Weissmann Norbert; Grimminger Friedrich; Seeger Werner
Hypoxia in lung vascular biology and disease.
Cardiovascular research 2006;71(4):618-9.
-
2006: Reichenberger F; Voswinckel R; Steveling E; Enke B; Kreckel A; Olschewski H; Grimminger F; Seeger W; Ghofrani H A
Sildenafil treatment for portopulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;28(3):563-7.
-
2006: Weissmann Norbert; Sommer Natascha; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Seeger Werner; Grimminger Friedrich
Oxygen sensors in hypoxic pulmonary vasoconstriction.
Cardiovascular research 2006;71(4):620-9.
-
2006: Ghofrani Hossein A; Osterloh Ian H; Grimminger Friedrich
Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.
Nature reviews. Drug discovery 2006;5(8):689-702.
-
2006: Ghofrani H A; Schermuly R T; Weissmann N; Seeger W; Grimminger F
[Reverse remodeling -- paradigm shift in the treatment of pulmonary hypertension]
Deutsche medizinische Wochenschrift (1946) 2006;131(16):871-4.
-
2006: Voswinckel R; Ahlbrecht K; Wolff J C; Weissmann N; Fehrenbach H; Yildirim A O; Grimminger F; Seeger W
[Pulmonary tissue regeneration -- a hope for the future]
Deutsche medizinische Wochenschrift (1946) 2006;131(16):865-8.
-
2006: Pullamsetti Soni Savai; Maring Daniel; Ghofrani Hossein Ardeschir; Mayer Konstantin; Weissmann Norbert; Rosengarten Bernhard; Lehner Martin; Schudt Christian; Boer Rainer; Grimminger Friedrich; Seeger Werner; Schermuly Ralph Theo
Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock.
Thrombosis and haemostasis 2006;95(4):720-7.
-
2006: Mayer K; Schaefer M; Walmrath H; Grimminger F; Seeger W
[Nutrition and immunonutrition in septic patients]
Der Internist 2006;47(4):374, 376-82.
-
2006: Pokreisz Peter; Fleming Ingrid; Kiss Ladislau; Barbosa-Sicard Eduardo; Fisslthaler Beate; Falck John R; Hammock Bruce D; Kim In-Hae; Szelid Zsolt; Vermeersch Pieter; Gillijns Hilde; Pellens Marijke; Grimminger Friedrich; van Zonneveld Anton-Jan; Collen Desire; Busse Rudi; Janssens Stefan
Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.
Hypertension 2006;47(4):762-70.
-
2006: Weissmann Norbert; Zeller Stefanie; Schäfer Rolf U; Turowski Carmen; Ay Mahmut; Quanz Karin; Ghofrani Hossein A; Schermuly Ralph T; Fink Ludger; Seeger Werner; Grimminger Friedrich
Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction.
American journal of respiratory cell and molecular biology 2006;34(4):505-13.
-
2006: Renigunta Aparna; Krasteva Gabriela; König Peter; Rose Frank; Klepetko Walter; Grimminger Friedrich; Seeger Werner; Hänze Jörg
DNA transfer into human lung cells is improved with Tat-RGD peptide by caveoli-mediated endocytosis.
Bioconjugate chemistry 2006;17(2):327-34.
-
2006: Savai Rajkumar; Schermuly Ralph Theo; Schneider Michael; Pullamsetti Soni Savai; Grimminger Friedrich; Seeger Werner; Banat Gamal-Andre
Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of lewis lung carcinoma in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(2):175-87.
-
2006: Hattar Katja; Grandel Ulrich; Moeller Alexander; Fink Ludger; Iglhaut Julia; Hartung Thomas; Morath Siegfried; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: Autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 generation.
Critical care medicine 2006;34(3):835-41.
-
2006: Renigunta Aparna; Hild Christiane; Rose Frank; Klepetko Walter; Grimminger Friedrich; Seeger Werner; Hänze Jörg
Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia.
FEBS letters 2006;580(3):900-3.
-
2006: Grimm Helmut; Mertes Norbert; Goeters Christiane; Schlotzer Ewald; Mayer Konstantin; Grimminger Friedrich; Fürst Peter
Improved fatty acid and leukotriene pattern with a novel lipid emulsion in surgical patients.
European journal of nutrition 2006;45(1):55-60.
-
2006: Voswinckel Robert; Ghofrani Hossein A; Grimminger Friedrich; Seeger Werner; Olschewski Horst
Inhaled treprostinil [corrected] for treatment of chronic pulmonary arterial hypertension.
Annals of internal medicine 2006;144(2):149-50.
-
2006: Dumitrascu Rio; Weissmann Norbert; Ghofrani Hossein Ardeschir; Dony Eva; Beuerlein Knut; Schmidt Harald; Stasch Johannes-Peter; Gnoth Mark Jean; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling.
Circulation 2006;113(2):286-95.
-
2006: Grandel Ulrich; Benkelmann Robin; Buerke Michael; Kiss Ladislau; Hattar Katja; Mayer Konstantin; Heep Martina; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Free arachidonic versus eicosapentaenoic acid differentially influences the potency of bacterial exotoxins to provoke myocardial depression in isolated rat hearts.
Critical care medicine 2006;34(1):118-26.
-
2006: Eul Bastian; Rose Frank; Krick Stefanie; Savai Rajkumar; Goyal Parag; Klepetko Walter; Grimminger Friedrich; Weissmann Norbert; Seeger Werner; Hänze Jörg
Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):163-5.
-
2006: Schermuly Ralph Theo; Schulz Andreas; Ghofrani Hossein Ardeschir; Breitenbach Christina Susanne; Weissmann Norbert; Hildebrand Michael; Kurz Julia; Grimminger Friedrich; Seeger Werner
Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(3):353-63.
-
2006: Weissmann Norbert; Schermuly Ralph T; Ghofrani Hossein A; Hänze Jörg; Goyal Parag; Grimminger Friedrich; Seeger Werner
Hypoxic pulmonary vasoconstriction--triggered by an increase in reactive oxygen species?
Novartis Foundation symposium 2006;272():196-208; discussion 208-17.
-
2006: Rosengarten B; Schermuly R T; Voswinckel R; Kohstall M G; Olschewski H; Weissmann N; Seeger W; Kaps M; Grimminger F; Ghofrani H A
Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension.
Cerebrovascular diseases (Basel, Switzerland) 2006;21(3):194-200.
-
2005: Galiè Nazzareno; Ghofrani Hossein A; Torbicki Adam; Barst Robyn J; Rubin Lewis J; Badesch David; Fleming Thomas; Parpia Tamiza; Burgess Gary; Branzi Angelo; Grimminger Friedrich; Kurzyna Marcin; Simonneau Gérald;
Sildenafil citrate therapy for pulmonary arterial hypertension.
The New England journal of medicine 2005;353(20):2148-57.
-
2005: Schermuly Ralph Theo; Dony Eva; Ghofrani Hossein Ardeschir; Pullamsetti Soni; Savai Rajkumar; Roth Markus; Sydykov Akylbek; Lai Ying Ju; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Reversal of experimental pulmonary hypertension by PDGF inhibition.
The Journal of clinical investigation 2005;115(10):2811-21.
-
2005: Savai Rajkumar; Wolf Joachim C; Greschus Susanne; Eul Bastian G; Schermuly Ralph T; Hänze Jörg; Voswinckel Robert; Langheinrich Alexander C; Grimminger Friedrich; Traupe Horst; Seeger Werner; Rose Frank
Analysis of tumor vessel supply in Lewis lung carcinoma in mice by fluorescent microsphere distribution and imaging with micro- and flat-panel computed tomography.
The American journal of pathology 2005;167(4):937-46.
-
2005: Vadász István; Morty Rory E; Olschewski Andrea; Königshoff Melanie; Kohstall Markus G; Ghofrani Hossein A; Grimminger Friedrich; Seeger Werner
Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase.
American journal of respiratory cell and molecular biology 2005;33(4):343-54.
-
2005: Hattar Katja; van Bürck Sandra; Bickenbach Annette; Grandel Ulrich; Maus Ulrich; Lohmeyer Jürgen; Csernok Elena; Hartung Thomas; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Anti-proteinase 3 antibodies (c-ANCA) prime CD14-dependent leukocyte activation.
Journal of leukocyte biology 2005;78(4):992-1000.
-
2005: Weissmann Norbert; Manz Daniel; Buchspies Daniela; Keller Stephan; Mehling Tanja; Voswinckel Robert; Quanz Karin; Ghofrani Hossein A; Schermuly Ralph T; Fink Ludger; Seeger Werner; Gassmann Max; Grimminger Friedrich
Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia.
Thrombosis and haemostasis 2005;94(3):630-8.
-
2005: Ghofrani Hossein A; Seeger Werner; Grimminger Friedrich
Imatinib for the treatment of pulmonary arterial hypertension.
The New England journal of medicine 2005;353(13):1412-3.
-
2005: Friese Georg; Lohmeyer Jürgen; Seeger Werner; Grimminger Friedrich; Ghofrani Hossein Ardeschir
[HIV-associated pulmonary hypertension ]
Herz 2005;30(6):481-5.
-
2005: Markart P; Hundack L; Ghofrani A; Grimminger F; Seeger W; Günther A
[Idiopathic interstitial pneumonias: pathomechanisms and therapeutic options]
Pneumologie (Stuttgart, Germany) 2005;59(8):554-61.
-
2005: Grandel Ulrich; Hopf Michael; Buerke Michael; Hattar Katja; Heep Martina; Fink Ludger; Bohle Rainer M; Morath Siegfried; Hartung Thomas; Pullamsetti Soni; Schermuly Ralph T; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Mechanisms of cardiac depression caused by lipoteichoic acids from Staphylococcus aureus in isolated rat hearts.
Circulation 2005;112(5):691-8.
-
2005: Savai Rajkumar; Schermuly Ralph Theo; Voswinckel Robert; Renigunta Aparna; Reichmann Bernd; Eul Bastian; Grimminger Friedrich; Seeger Werner; Rose Frank; Hänze Jörg
HIF-1alpha attenuates tumor growth in spite of augmented vascularization in an A549 adenocarcinoma mouse model.
International journal of oncology 2005;27(2):393-400.
-
2005: Schermuly Ralph Theo; Yilmaz Hüseyin; Ghofrani Hossein Ardeschir; Woyda Kathrin; Pullamsetti Soni; Schulz Andreas; Gessler Tobias; Dumitrascu Rio; Weissmann Norbert; Grimminger Friedrich; Seeger Werner
Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.
American journal of respiratory and critical care medicine 2005;172(3):358-63.
-
2005: Pullamsetti Soni; Kiss Ladislau; Ghofrani Hossein Ardeschir; Voswinckel Robert; Haredza Peter; Klepetko Walter; Aigner Clemens; Fink Ludger; Muyal Jai Prakash; Weissmann Norbert; Grimminger Friedrich; Seeger Werner; Schermuly Ralph Theo
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1175-7.
-
2005: Ghofrani Hossein Ardeschir; Voswinckel Robert; Reichenberger Frank; Grimminger Friedrich; Seeger Werner
[Emerging therapies for the treatment of pulmonary arterial hypertension]
Herz 2005;30(4):296-302.
-
2005: Krick Stefanie; Hänze Jörg; Eul Bastian; Savai Rajkumar; Seay Ulrike; Grimminger Friedrich; Lohmeyer Jürgen; Klepetko Walter; Seeger Werner; Rose Frank
Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):857-9.
-
2005: Krick Stefanie; Eul Bastian G; Hänze Jörg; Savai Rajkumar; Grimminger Friedrich; Seeger Werner; Rose Frank
Role of hypoxia-inducible factor-1alpha in hypoxia-induced apoptosis of primary alveolar epithelial type II cells.
American journal of respiratory cell and molecular biology 2005;32(5):395-403.
-
2005: Goyal Parag; Weissmann Norbert; Rose Frank; Grimminger Friedrich; Schäfers Hans J; Seeger Werner; Hänze Jörg
Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells.
Biochemical and biophysical research communications 2005;329(1):32-9.
-
2005: Olschewski H; Ghofrani A; Enke B; Reichenberger F; Voswinckel R; Kreckel A; Ghofrani S; Wiedemann R; Schulz R; Grimminger F; Seeger W
[Therapy of pulmonary arterial hypertension]
Der Internist 2005;46(3):341-9.
-
2005: Vadász István; Morty Rory E; Kohstall Markus G; Olschewski Andrea; Grimminger Friedrich; Seeger Werner; Ghofrani Hossein A
Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome?
American journal of respiratory and critical care medicine 2005;171(5):469-79.
-
2005: Pullamsetti Soni; Krick Stefanie; Yilmaz Hüseyin; Ghofrani Hossein Ardeschir; Schudt Christian; Weissmann Norbert; Fuchs Beate; Seeger Werner; Grimminger Friedrich; Schermuly Ralph Theo
Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration.
Respiratory research 2005;6():128.
-
2005: Weissmann Norbert; Kuzkaya Nermin; Fuchs Beate; Tiyerili Vedat; Schäfer Rolf U; Schütte Hartwig; Ghofrani Hossein A; Schermuly Ralph T; Schudt Christian; Sydykov Akylbek; Egemnazarow Bakytbek; Seeger Werner; Grimminger Friedrich
Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy.
Respiratory research 2005;6():86.
-
2005: Schermuly Ralph Theo; Inholte Christiane; Ghofrani Hossein Ardeschir; Gall Henning; Weissmann Norbert; Weidenbach Andreas; Seeger Werner; Grimminger Friedrich
Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.
Respiratory research 2005;6():76.
-
2004: Schmidt R; Luboeinski T; Markart P; Ruppert C; Daum C; Grimminger F; Seeger W; Günther A
Alveolar antioxidant status in patients with acute respiratory distress syndrome.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(6):994-9.
-
2004: Ghofrani Hossein A; Voswinckel Robert; Reichenberger Frank; Olschewski Horst; Haredza Peter; Karadas Burcu; Schermuly Ralph T; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study.
Journal of the American College of Cardiology 2004;44(7):1488-96.
-
2004: Wygrecka Malgorzata; Markart Philipp; Ruppert Clemens; Kuchenbuch Tim; Fink Ludger; Bohle Rainer Maria; Grimminger Friedrich; Seeger Werner; Günther Andreas
Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application.
Thrombosis and haemostasis 2004;92(3):529-40.
-
2004: Ghofrani Hossein A; Reichenberger Frank; Kohstall Markus G; Mrosek Eike H; Seeger Timon; Olschewski Horst; Seeger Werner; Grimminger Friedrich
Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial.
Annals of internal medicine 2004;141(3):169-77.
-
2004: Ghofrani Hossein A; Pepke-Zaba Joanna; Barbera Joan A; Channick Richard; Keogh Anne M; Gomez-Sanchez Miguel A; Kneussl Meinhard; Grimminger Friedrich
Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension.
Journal of the American College of Cardiology 2004;43(12 Suppl S):68S-72S.
-
2004: Goyal Parag; Weissmann Norbert; Grimminger Friedrich; Hegel Cornelia; Bader Lucius; Rose Frank; Fink Ludger; Ghofrani Hossein A; Schermuly Ralph T; Schmidt Harald H H W; Seeger Werner; Hänze Jörg
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species.
Free radical biology & medicine 2004;36(10):1279-88.
-
2004: Schermuly Ralph Theo; Kreisselmeier Klaus Peter; Ghofrani Hossein Ardeschir; Samidurai Arun; Pullamsetti Soni; Weissmann Norbert; Schudt Christian; Ermert Leander; Seeger Werner; Grimminger Friedrich
Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.
Circulation research 2004;94(8):1101-8.
-
2004: Weissmann Norbert; Vogels Henrik; Schermuly Ralph T; Ghofrani Hossein A; Hänze Jörg; Fink Ludger; Rose Frank; Seeger Werner; Grimminger Friedrich
Measurement of exhaled hydrogen peroxide from rabbit lungs.
Biological chemistry 2004;385(3-4):259-64.
-
2004: Ghofrani H A; Friese G; Discher T; Olschewski H; Schermuly R T; Weissmann N; Seeger W; Grimminger F; Lohmeyer J
Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;23(2):321-6.
-
2004: Weissmann Norbert; Akkayagil Ercan; Quanz Karin; Schermuly Ralph Theo; Ghofrani Hossein Ardeschir; Fink Ludger; Hänze Jörg; Rose Frank; Seeger Werner; Grimminger Friedrich
Basic features of hypoxic pulmonary vasoconstriction in mice.
Respiratory physiology & neurobiology 2004;139(2):191-202.
-
2004: Schmidt Reinhold; Schäfer Christoph; Luboeinski Thomas; Löckinger Alexander; Hermle Gerd; Grimminger Friedrich; Seeger Werner; Ghofrani Ardeschir; Schütte Hartwig; Günther Andreas
Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia.
Free radical biology & medicine 2004;36(1):78-89.
-
2004: Muth H; Maus U; Wygrecka M; Lohmeyer J; Grimminger F; Seeger W; Günther A
Pro- and antifibrinolytic properties of human pulmonary microvascular versus artery endothelial cells: impact of endotoxin and tumor necrosis factor-alpha.
Critical care medicine 2004;32(1):217-26.
-
2004: Schermuly Ralph T; Kreisselmeier Klaus P; Ghofrani Hossein A; Yilmaz Hüseyin; Butrous Ghazwan; Ermert Leander; Ermert Monika; Weissmann Norbert; Rose Frank; Guenther Andreas; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats.
American journal of respiratory and critical care medicine 2004;169(1):39-45.
-
2003: Hänze Jörg; Eul Bastian G; Savai Rajkumar; Krick Stefanie; Goyal Parag; Grimminger Friedrich; Seeger Werner; Rose Frank
RNA interference for HIF-1alpha inhibits its downstream signalling and affects cellular proliferation.
Biochemical and biophysical research communications 2003;312(3):571-7.
-
2003: Eickelberg Oliver; Yeager Michael E; Grimminger Friedrich
The tantalizing triplet of pulmonary hypertension-BMP receptors, serotonin receptors, and angiopoietins.
Cardiovascular research 2003;60(3):465-7.
-
2003: Rose Frank; Hattar Katja; Gakisch Sybille; Grimminger Friedrich; Olschewski Horst; Seeger Werner; Tschuschner Annette; Schermuly Ralph T; Weissmann Norbert; Hanze Jörg; Sibelius Ulf; Ghofrani Hossein A
Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost.
Thrombosis and haemostasis 2003;90(6):1141-9.
-
2003: Günther Andreas; Lübke Norbert; Ermert Monika; Schermuly Ralph T; Weissmann Norbert; Breithecker Andreas; Markart Philipp; Ruppert Clemens; Quanz Karin; Ermert Leander; Grimminger Friedrich; Seeger Werner
Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits.
American journal of respiratory and critical care medicine 2003;168(11):1358-65.
-
2003: Weissmann Norbert; Ebert Nadine; Ahrens Marit; Ghofrani Hossein A; Schermuly Ralph T; Hänze Jörg; Fink Ludger; Rose Frank; Conzen Jörg; Seeger Werner; Grimminger Friedrich
Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs.
American journal of respiratory cell and molecular biology 2003;29(6):721-32.
-
2003: Mayer Konstantin; Meyer Sandra; Reinholz-Muhly Marion; Maus Ulrich; Merfels Martina; Lohmeyer Jürgen; Grimminger Friedrich; Seeger Werner
Short-time infusion of fish oil-based lipid emulsions, approved for parenteral nutrition, reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium in humans.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4837-43.
-
2003: Mayer Konstantin; Fegbeutel Christine; Hattar Katja; Sibelius Ulf; Krämer Hans-Joachim; Heuer Kai-Uwe; Temmesfeld-Wollbrück Bettina; Gokorsch Stephanie; Grimminger Friedrich; Seeger Werner
Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation.
Intensive care medicine 2003;29(9):1472-81.
-
2003: Schermuly R T; Leuchte H; Ghofrani H A; Weissmann N; Rose F; Kohstall M; Olschewski H; Schudt C; Grimminger F; Seeger W; Walmrath D
Zardaverine and aerosolised iloprost in a model of acute respiratory failure.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(2):342-7.
-
2003: Ghofrani Hossein A; Rose Frank; Schermuly Ralph T; Olschewski Horst; Wiedemann Ralph; Kreckel André; Weissmann Norbert; Ghofrani Stefanie; Enke Beate; Seeger Werner; Grimminger Friedrich
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension.
Journal of the American College of Cardiology 2003;42(1):158-64.
-
2003: Ermert M; Pantazis C; Duncker H-R; Grimminger F; Seeger W; Ermert L
In situ localization of TNFalpha/beta, TACE and TNF receptors TNF-R1 and TNF-R2 in control and LPS-treated lung tissue.
Cytokine 2003;22(3-4):89-100.
-
2003: Mayer Konstantin; Gokorsch Stephanie; Fegbeutel Christine; Hattar Katja; Rosseau Simone; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis.
American journal of respiratory and critical care medicine 2003;167(10):1321-8.
-
2003: Schulz Richard; Fegbeutel Christine; Althoff Andre; Traupe Horst; Grimminger Friedrich; Seeger Werner
Central sleep apnoea and unilateral diaphragmatic paralysis associated with vertebral artery compression of the medulla oblongata.
Journal of neurology 2003;250(4):503-5.
-
2003: Ghofrani Hossein A; Schermuly Ralph T; Rose Frank; Wiedemann Ralph; Kohstall Markus G; Kreckel André; Olschewski Horst; Weissmann Norbert; Enke Beate; Ghofrani Stefanie; Seeger Werner; Grimminger Friedrich
Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension.
American journal of respiratory and critical care medicine 2003;167(8):1139-41.
-
2003: Schütte Hartwig; Schell Alexander; Schäfer Christoph; Ghofrani Ardeschir; Theo Schermuly Ralph; Seeger Werner; Grimminger Friedrich
Subthreshold doses of nebulized prostacyclin and rolipram synergistaically protect against lung ischemia-reperfusion.
Transplantation 2003;75(6):814-21.
-
2003: Sibelius Ulf; Grandel Ulrich; Buerke Michael; Kiss Ladislau; Klingenberger Pascal; Heep Martina; Bournelis Emmanoyil; Seeger Werner; Grimminger Friedrich
Leukotriene-mediated coronary vasoconstriction and loss of myocardial contractility evoked by low doses of Escherichia coli hemolysin in perfused rat hearts.
Critical care medicine 2003;31(3):683-8.
-
2003: Weissmann Norbert; Nollen Matthias; Gerigk Boris; Ardeschir Ghofrani Hossein; Schermuly Ralph Theo; Gunther Andreas; Quanz Karin; Fink Ludger; Hänze Jörg; Rose Frank; Seeger Werner; Grimminger Friedrich
Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H931-8.
-
2003: Ruppert Clemens; Markart Philipp; Schmidt Reinhold; Grimminger Friedrich; Seeger Werner; Lehr Claus-Michael; Günther Andreas
Chemical crosslinking of urokinase to pulmonary surfactant protein B for targeting alveolar fibrin.
Thrombosis and haemostasis 2003;89(1):53-64.
-
2003: Dailey Lea Ann; Schmehl Thomas; Gessler Tobias; Wittmar Matthias; Grimminger Friedrich; Seeger Werner; Kissel Thomas
Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features.
Journal of controlled release : official journal of the Controlled Release Society 2003;86(1):131-44.
-
2003: Markart Philipp; Ruppert Clemens; Grimminger Friedrich; Seeger Werner; Günther Andreas
Fibrinolysis-inhibitory capacity of clot-embedded surfactant is enhanced by SP-B and SP-C.
American journal of physiology. Lung cellular and molecular physiology 2003;284(1):L69-76.
-
2003: Grandel Ulrich; Grimminger Friedrich
Endothelial responses to bacterial toxins in sepsis.
Critical reviews in immunology 2003;23(4):267-99.
-
2002: Olschewski H; Ghofrani A; Wiedemann R; Rose F; Enke B; Gessler T; Voswinckel R; Kohstall M; Grimminger F; Seeger W
[Pulmonary hypertension]
Der Internist 2002;43(12):1498, 1501-9.
-
2002: Ghofrani H A; Olschewski H; Seeger W; Grimminger F
[Sildenafil for treatment of severe pulmonary hypertension and commencing right-heart failure]
Pneumologie (Stuttgart, Germany) 2002;56(11):665-72.
-
2002: Ghofrani Hossein A; Rose Frank; Schermuly Ralph T; Olschewski Horst; Wiedemann Ralph; Weissmann Norbert; Schudt Christian; Tenor Herrmann; Seeger Werner; Grimminger Friedrich
Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension.
Critical care medicine 2002;30(11):2489-92.
-
2002: Schermuly Ralph Theo; Schulz Andreas; Ghofrani Hossein Ardeschir; Meidow Arne; Rose Frank; Roehl Axel; Weissmann Norbert; Hildebrand Michael; Kurz Julia; Grimminger Friedrich; Walmrath Dieter; Seeger Werner
Pharmacokinetics and metabolism of infused versus inhaled iloprost in isolated rabbit lungs.
The Journal of pharmacology and experimental therapeutics 2002;303(2):741-5.
-
2002: Schmidt R; Meier U; Markart P; Grimminger F; Velcovsky H G; Morr H; Seeger W; Günther A
Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology 2002;283(5):L1079-85.
-
2002: Sibelius Ulf; Hattar Katja; Hoffmann Sabine; Mayer Konstantin; Grandel Ulrich; Schenkel Angelika; Seeger Werner; Grimminger Friedrich
Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.
Critical care medicine 2002;30(10):2306-12.
-
2002: Pruefer Diethard; Makowski Joachim; Schnell Martin; Buerke Ute; Dahm Manfred; Oelert Hellmut; Sibelius Ulf; Grandel Ulrich; Grimminger Friedrich; Seeger Werner; Meyer Jürgen; Darius Harald; Buerke Michael
Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin.
Circulation 2002;106(16):2104-10.
-
2002: Rose Frank; Grimminger Friedrich; Appel Jutta; Heller Mathias; Pies Volker; Weissmann Norbert; Fink Ludger; Schmidt Sebastian; Krick Stefanie; Camenisch Gieri; Gassmann Max; Seeger Werner; Hänze Jörg
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1660-1.
-
2002: Ghofrani Hossein Ardeschir; Wiedemann Ralph; Rose Frank; Schermuly Ralph T; Olschewski Horst; Weissmann Norbert; Gunther Andreas; Walmrath Dieter; Seeger Werner; Grimminger Friedrich
Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial.
Lancet 2002;360(9337):895-900.
-
2002: Rose Frank; Guthmann Bernd; Tenenbaum Tobias; Fink Ludger; Ghofrani Ardeschir; Weissmann Norbert; König Peter; Ermert Leander; Dahlem Gabriele; Haenze Joerg; Kummer Wolfgang; Seeger Werner; Grimminger Friedrich
Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1474-81.
-
2002: Mayer Konstantin; Merfels Martina; Muhly-Reinholz Marion; Gokorsch Stephanie; Rosseau Simone; Lohmeyer Jürgen; Schwarzer Nicole; Krüll Matthias; Suttorp Norbert; Grimminger Friedrich; Seeger Werner
Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation.
American journal of physiology. Heart and circulatory physiology 2002;283(2):H811-8.
-
2002: Ruppert Clemens; Schmidt Reinhold; Grimminger Friedrich; Suzuki Yasuhiro; Seeger Werner; Lehr Claus-Michael; Günther Andreas
Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin.
Bioconjugate chemistry 2002;13(4):804-11.
-
2002: George W; Grimminger F; Krause B
[Communication center in public health]
Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V 2002;54(2):84-8.
-
2002: Hattar Katja; Bickenbach Annette; Csernok Elena; Rosseau Simone; Grandel Ulrich; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Wegener's granulomatosis: antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release-role of autocrine cell activation.
Journal of leukocyte biology 2002;71(6):996-1004.
-
2002: Mayer Konstantin; Schmidt Reinhold; Muhly-Reinholz Marion; Bögeholz Tina; Gokorsch Stephanie; Grimminger Friedrich; Seeger Werner
In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFalpha impact of omega-3 versus omega-6 fatty acids.
Journal of lipid research 2002;43(6):944-51.
-
2002: Walmrath D; Grimminger F; Pappert D; Knothe C; Obertacke U; Benzing A; Günther A; Schmehl T; Leuchte H; Seeger W
Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on gas exchange and haemodynamics.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(5):805-10.
-
2002: Günther A; Schmidt R; Harodt J; Schmehl T; Walmrath D; Ruppert C; Grimminger F; Seeger W
Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on biophysical and biochemical surfactant properties.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(5):797-804.
-
2002: Mayser Peter; Mayer Konstantin; Mahloudjian Mojgan; Benzing Steffen; Krämer Hans-Joachim; Schill Wolf-Bernhard; Seeger Werner; Grimminger Friedrich
A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis.
JPEN. Journal of parenteral and enteral nutrition 2002;26(3):151-8.
-
2002: Ghofrani H A; Wiedemann R; Rose F; Weissmann N; Schermuly R T; Quanz K; Grimminger F; Seeger W; Olschewski H
Lung cGMP release subsequent to NO inhalation in pulmonary hypertension: responders versus nonresponders.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(4):664-71.
-
2002: Schulz R; Baseler G; Ghofrani H A; Grimminger F; Olschewski H; Seeger W
Nocturnal periodic breathing in primary pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(4):658-63.
-
2002: Ghofrani Hossein Ardeschir; Wiedemann Ralph; Rose Frank; Olschewski Horst; Schermuly Ralph Theo; Weissmann Norbert; Seeger Werner; Grimminger Friedrich
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.
Annals of internal medicine 2002;136(7):515-22.
-
2002: Hattar Katja; Grandel Ulrich; Bickenbach Annette; Schwarting Andreas; Mayet Werner-Johannes; Bux Jürgen; Jessen Sönke; Fischer Claus; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Interaction of antibodies to proteinase 3 (classic anti-neutrophil cytoplasmic antibody) with human renal tubular epithelial cells: impact on signaling events and inflammatory mediator generation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):3057-64.
-
2002: Hänze Jörg; Groneberg David A; Rose Frank; Hanisch Anika; Dötsch Jörg; Peiser Christian; Seeger Werner; Rascher Wolfgang; Fischer Axel; Grimminger Friedrich
Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia.
Biochemical and biophysical research communications 2002;291(5):1160-5.
-
2002: Grandel Ulrich; Reutemann Mathias; Kiss Ladislau; Buerke Michael; Fink Ludger; Bournelis Emmanoyil; Heep Martina; Seeger Werner; Grimminger Friedrich; Sibelius Ulf
Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes.
American journal of physiology. Heart and circulatory physiology 2002;282(3):H1157-65.
-
2002: Schmidt Reinhold; Steinhilber Wolfram; Ruppert Clemens; Daum Christina; Grimminger Friedrich; Seeger Werner; Günther Andreas
An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid.
American journal of respiratory and critical care medicine 2002;165(4):470-4.
-
2002: Rose Frank; Dahlem Gabriele; Guthmann Bernd; Grimminger Friedrich; Maus Ulrich; Hänze Jörg; Duemmer Nils; Grandel Ulrich; Seeger Werner; Ghofrani Hossein Ardeschir
Mediator generation and signaling events in alveolar epithelial cells attacked by S. aureus alpha-toxin.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L207-14.
-
2002: Mayser P; Grimm H; Grimminger F
n-3 fatty acids in psoriasis.
The British journal of nutrition 2002;87 Suppl 1():S77-82.
-
2002: Mayer K; Grimm H; Grimminger F; Seeger W
Parenteral nutrition with n-3 lipids in sepsis.
The British journal of nutrition 2002;87 Suppl 1():S69-75.
-
2002: Buerke Michael; Sibelius Ulf; Grandel Ulrich; Buerke Ute; Grimminger Friedrich; Seeger Werner; Meyer Jürgen; Darius Harald
Staphylococcus aureus alpha toxin mediates polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction.
Shock (Augusta, Ga.) 2002;17(1):30-5.
-
2002: Fink Ludger; Kohlhoff Stephanie; Stein Maria Magdalena; Hänze Jörg; Weissmann Norbert; Rose Frank; Akkayagil Ercan; Manz Daniel; Grimminger Friedrich; Seeger Werner; Bohle Rainer Maria
cDNA array hybridization after laser-assisted microdissection from nonneoplastic tissue.
The American journal of pathology 2002;160(1):81-90.
-
2002: Schulz Richard; Hummel Christoph; Heinemann Sabine; Seeger Werner; Grimminger Friedrich
Serum levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea and severe nighttime hypoxia.
American journal of respiratory and critical care medicine 2002;165(1):67-70.
-
2002: Gessler Tobias; Schmehl Thomas; Olschewski Horst; Grimminger Friedrich; Seeger Werner
Aerosolized vasodilators in pulmonary hypertension.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(2):117-22.
-
2001: Walmrath D; Grimminger F; Seeger W
[Severe sepsis--new therapeutic options]
Der Internist 2001;42(12):1619-20, 1623-30.
-
2001: Olschewski H; Rose F; Grünig E; Ghofrani H A; Walmrath D; Schulz R; Schermuly R; Grimminger F; Seeger W
Cellular pathophysiology and therapy of pulmonary hypertension.
The Journal of laboratory and clinical medicine 2001;138(6):367-77.
-
2001: Schermuly R T; Roehl A; Weissmann N; Ghofrani H A; Leuchte H; Grimminger F; Seeger W; Walmrath D
Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2001;281(6):L1361-8.
-
2001: Schulz R; Seeger W; Grimminger F
Serum nitrite/nitrate levels in obstructive sleep apnea.
American journal of respiratory and critical care medicine 2001;164(10 Pt 1):1997-8.
-
2001: Schermuly R T; Krupnik E; Tenor H; Schudt C; Weissmann N; Rose F; Grimminger F; Seeger W; Walmrath D; Ghofrani H A
Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.
American journal of respiratory and critical care medicine 2001;164(9):1694-700.
-
2001: Olschewski H; Olschewski A; Rose F; Schermuly R; Schütte H; Weissmann N; Seeger W; Grimminger F
Physiologic basis for the treatment of pulmonary hypertension.
The Journal of laboratory and clinical medicine 2001;138(5):287-97.
-
2001: Schütte H; Witzenrath M; Mayer K; Rosseau S; Seeger W; Grimminger F
Short-term "preconditioning" with inhaled nitric oxide protects rabbit lungs against ischemia-reperfusion injury.
Transplantation 2001;72(8):1363-70.
-
2001: Wiedemann R; Ghofrani H A; Weissmann N; Schermuly R; Quanz K; Grimminger F; Seeger W; Olschewski H
Atrial natriuretic peptide in severe primary and nonprimary pulmonary hypertension: response to iloprost inhalation.
Journal of the American College of Cardiology 2001;38(4):1130-6.
-
2001: Schermuly R T; Weissmann N; Enke B; Ghofrani H A; Forssmann W G; Grimminger F; Seeger W; Walmrath D
Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.
American journal of respiratory cell and molecular biology 2001;25(2):219-25.
-
2001: Schütte H; Mayer K; Burger H; Witzenrath M; Gessler T; Seeger W; Grimminger F
Endogenous nitric oxide synthesis and vascular leakage in ischemic-reperfused rabbit lungs.
American journal of respiratory and critical care medicine 2001;164(3):412-8.
-
2001: Weissmann N; Grimminger F; Olschewski A; Seeger W
Hypoxic pulmonary vasoconstriction: a multifactorial response?
American journal of physiology. Lung cellular and molecular physiology 2001;281(2):L314-7.
-
2001: Schütte H; Löckinger A; Seeger W; Grimminger F
Aerosolized PGE1, PGI2 and nitroprusside protect against vascular leakage in lung ischaemia-reperfusion.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(1):15-22.
-
2001: Günther A; Walmrath D; Grimminger F; Seeger W
Pathophysiology of acute lung injury.
Seminars in respiratory and critical care medicine 2001;22(3):247-58.
-
2001: Schulz R; Olschewski H; Grimminger F; Seeger W
[Obstructive sleep apnea and cardiovascular diseases--hypothesis on the pathophysiological interlinks]
Pneumologie (Stuttgart, Germany) 2001;55(6):295-301.
-
2001: Hattar K; Fink L; Fietzner K; Himmel B; Grimminger F; Seeger W; Sibelius U
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6287-93.
-
2001: Ghofrani H A; Kohstall M G; Weissmann N; Schmehl T; Schermuly R T; Seeger W; Grimminger F
Alveolar epithelial barrier functions in ventilated perfused rabbit lungs.
American journal of physiology. Lung cellular and molecular physiology 2001;280(5):L896-904.
-
2001: Schermuly R T; Günther A; Ermert M; Ermert L; Ghofrani H A; Weissmann N; Grimminger F; Seeger W; Walmrath D
Conebulization of surfactant and urokinase restores gas exchange in perfused lungs with alveolar fibrin formation.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L792-800.
-
2001: Weissmann N; Winterhalder S; Nollen M; Voswinckel R; Quanz K; Ghofrani H A; Schermuly R T; Seeger W; Grimminger F
NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L638-45.
-
2001: Rose F; Zeller S A; Chakraborty T; Domann E; Machleidt T; Kronke M; Seeger W; Grimminger F; Sibelius U
Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors.
Infection and immunity 2001;69(2):897-905.
-
2001: Gessler T; Schmehl T; Hoeper M M; Rose F; Ghofrani H A; Olschewski H; Grimminger F; Seeger W
Ultrasonic versus jet nebulization of iloprost in severe pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(1):14-9.
-
2001: Löckinger A; Schütte H; Walmrath D; Seeger W; Grimminger F
Protection against gas exchange abnormalities by pre-aerosolized PGE1, iloprost and nitroprusside in lung ischemia-reperfusion.
Transplantation 2001;71(2):185-93.
-
2001: Schmidt R; Meier U; Yabut-Perez M; Walmrath D; Grimminger F; Seeger W; Günther A
Alteration of fatty acid profiles in different pulmonary surfactant phospholipids in acute respiratory distress syndrome and severe pneumonia.
American journal of respiratory and critical care medicine 2001;163(1):95-100.
-
2001: Hattar K; Sibelius U; Bickenbach A; Csernok E; Seeger W; Grimminger F
Subthreshold concentrations of anti-proteinase 3 antibodies (c-ANCA) specifically prime human neutrophils for fMLP-induced leukotriene synthesis and chemotaxis.
Journal of leukocyte biology 2001;69(1):89-97.
-
2001: Grandel U; Sibelius U; Schrickel J; Schmidt D; Buerke M; Fink L; Bournelis E; Heep M; Mayer K; Bohle R M; Seeger W; Grimminger F
Biosynthesis of constitutive nitric oxide synthase-derived nitric oxide attenuates coronary vasoconstriction and myocardial depression in a model of septic heart failure induced by Staphylococcus aureus alpha-toxin.
Critical care medicine 2001;29(1):1-7.
-
2001: Maus U; Herold S; Muth H; Maus R; Ermert L; Ermert M; Weissmann N; Rosseau S; Seeger W; Grimminger F; Lohmeyer J
Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14.
American journal of physiology. Lung cellular and molecular physiology 2001;280(1):L58-68.
-
2001: Günther A; Ruppert C; Schmidt R; Markart P; Grimminger F; Walmrath D; Seeger W
Surfactant alteration and replacement in acute respiratory distress syndrome.
Respiratory research 2001;2(6):353-64.
-
2000: Schulz R; Olschewski H; Grimminger F; Seeger W
[Prevalence of stroke and transitory ischemic attacks in obstructive sleep apnea: a retrospective analyis so f 187 consecutive patients]
Pneumologie (Stuttgart, Germany) 2000;54(12):575-9.
-
2000: Schulz R; Schmidt D; Blum A; Lopes-Ribeiro X; Lücke C; Mayer K; Olschewski H; Seeger W; Grimminger F
Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy.
Thorax 2000;55(12):1046-51.
-
2000: Grandel U; Fink L; Blum A; Heep M; Buerke M; Kraemer H J; Mayer K; Bohle R M; Seeger W; Grimminger F; Sibelius U
Endotoxin-induced myocardial tumor necrosis factor-alpha synthesis depresses contractility of isolated rat hearts: evidence for a role of sphingosine and cyclooxygenase-2-derived thromboxane production.
Circulation 2000;102(22):2758-64.
-
2000: Weissmann N; Tadic A; Hänze J; Rose F; Winterhalder S; Nollen M; Schermuly R T; Ghofrani H A; Seeger W; Grimminger F
Hypoxic vasoconstriction in intact lungs: a role for NADPH oxidase-derived H(2)O(2)?
American journal of physiology. Lung cellular and molecular physiology 2000;279(4):L683-90.
-
2000: Schütte H; Witzenrath M; Mayer K; Weissmann N; Schell A; Rosseau S; Seeger W; Grimminger F
The PDE inhibitor zaprinast enhances NO-mediated protection against vascular leakage in reperfused lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;279(3):L496-502.
-
2000: Temmesfeld-Wollbrück B; Mayer K; Grimminger F
Assessment of intestinal tissue oxygenation: the canary sings--but was does the twitter tell us?
Intensive care medicine 2000;26(8):1025-7.
-
2000: Schulz R; Mahmoudi S; Hattar K; Sibelius U; Olschewski H; Mayer K; Seeger W; Grimminger F
Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):566-70.
-
2000: Weissmann N; Voswinckel R; Tadic A; Hardebusch T; Ghofrani H A; Schermuly R T; Seeger W; Grimminger F
Nitric oxide (NO)-dependent but not NO-independent guanylate cyclase activation attenuates hypoxic vasoconstriction in rabbit lungs.
American journal of respiratory cell and molecular biology 2000;23(2):222-7.
-
2000: Rose F; Kiss L; Grimminger F; Mayer K; Grandel U; Seeger W; Bieniek E; Sibelius U
E. coli hemolysin-induced lipid mediator metabolism in alveolar macrophages: impact of eicosapentaenoic acid.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L100-9.
-
2000: Rosseau S; Hammerl P; Maus U; Walmrath H D; Schütte H; Grimminger F; Seeger W; Lohmeyer J
Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L25-35.
-
2000: Rose F; Heuer K U; Sibelius U; Hombach-Klonisch S; Kiss L; Seeger W; Grimminger F
Targeting lipopolysaccharides by the nontoxic polymyxin B nonapeptide sensitizes resistant Escherichia coli to the bactericidal effect of human neutrophils.
The Journal of infectious diseases 2000;182(1):191-9.
-
2000: Grimminger F; Rose F; Ghofrani H A; Schermuly R T; Weissmann N; Olschewski H; Walmrath D; Seeger W
[Inhalative strategies for improvement of pulmonary hemodynamics and gas exchange in sepsis and severe pulmonary hypertension]
Zeitschrift für Kardiologie 2000;89(6):477-84.
-
2000: Günther A; Mosavi P; Ruppert C; Heinemann S; Temmesfeld B; Velcovsky H G; Morr H; Grimminger F; Walmrath D; Seeger W
Enhanced tissue factor pathway activity and fibrin turnover in the alveolar compartment of patients with interstitial lung disease.
Thrombosis and haemostasis 2000;83(6):853-60.
-
2000: Kiss L; Schütte H; Mayer K; Grimm H; Padberg W; Seeger W; Grimminger F
Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature.
American journal of respiratory and critical care medicine 2000;161(6):1917-23.
-
2000: Jörres R A; Holz O; Zachgo W; Timm P; Koschyk S; Müller B; Grimminger F; Seeger W; Kelly F J; Dunster C; Frischer T; Lubec G; Waschewski M; Niendorf A; Magnussen H
The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies.
American journal of respiratory and critical care medicine 2000;161(6):1855-61.
-
2000: Ermert M; Merkle M; Mootz R; Grimminger F; Seeger W; Ermert L
Endotoxin priming of the cyclooxygenase-2-thromboxane axis in isolated rat lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;278(6):L1195-203.
-
2000: Ermert L; Ermert M; Merkle M; Goppelt-Struebe M; Duncker H R; Grimminger F; Seeger W
Rat pulmonary cyclooxygenase-2 expression in response to endotoxin challenge: differential regulation in the various types of cells in the lung.
The American journal of pathology 2000;156(4):1275-87.
-
2000: Ermert L; Ermert M; Duncker H R; Grimminger F; Seeger W
In situ localization and regulation of thromboxane A(2) synthase in normal and LPS-primed lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;278(4):L744-53.
-
2000: Olschewski H; Ghofrani H A; Walmrath D; Schermuly R; Temmesfeld-Wollbrück B; Grimminger F; Seeger W
[Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to pulmonary fibrosis]
Pneumologie (Stuttgart, Germany) 2000;54(3):133-42.
-
2000: Günther A; Mosavi P; Heinemann S; Ruppert C; Muth H; Markart P; Grimminger F; Walmrath D; Temmesfeld-Wollbrück B; Seeger W
Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):454-62.
-
2000: Grimminger F; Mayer K; Kiss L; Walmrath D; Seeger W
PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L268-75.
-
2000: Schermuly R T; Roehl A; Weissmann N; Ghofrani H A; Schudt C; Tenor H; Grimminger F; Seeger W; Walmrath D
Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange.
The Journal of pharmacology and experimental therapeutics 2000;292(2):512-20.
-
2000: Schermuly R T; Günther A; Weissmann N; Ghofrani H A; Seeger W; Grimminger F; Walmrath D
Differential impact of ultrasonically nebulized versus tracheal-instilled surfactant on ventilation-perfusion (VA/Q) mismatch in a model of acute lung injury.
American journal of respiratory and critical care medicine 2000;161(1):152-9.
-
2000: Sibelius U; Grandel U; Buerke M; Mueller D; Kiss L; Kraemer H J; Braun-Dullaeus R; Haberbosch W; Seeger W; Grimminger F
Staphylococcal alpha-toxin provokes coronary vasoconstriction and loss in myocardial contractility in perfused rat hearts: role of thromboxane generation.
Circulation 2000;101(1):78-85.
-
2000: Rosseau S; Selhorst J; Wiechmann K; Leissner K; Maus U; Mayer K; Grimminger F; Seeger W; Lohmeyer J
Monocyte migration through the alveolar epithelial barrier: adhesion molecule mechanisms and impact of chemokines.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):427-35.
-
1999: Günther A; Markart P; Kalinowski M; Ruppert C; Grimminger F; Seeger W
Cleavage of surfactant-incorporating fibrin by different fibrinolytic agents. Kinetics of lysis and rescue of surface activity.
American journal of respiratory cell and molecular biology 1999;21(6):738-45.
-
1999: Schermuly R T; Ghofrani H A; Enke B; Weissmann N; Grimminger F; Seeger W; Schudt C; Walmrath D
Low-dose systemic phosphodiesterase inhibitors amplify the pulmonary vasodilatory response to inhaled prostacyclin in experimental pulmonary hypertension.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1500-6.
-
1999: Rosseau S; Hammerl P; Maus U; Günther A; Seeger W; Grimminger F; Lohmeyer J
Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4495-502.
-
1999: Hermle G; Schütte H; Walmrath D; Geiger K; Seeger W; Grimminger F
Ventilation-perfusion mismatch after lung ischemia-reperfusion. Protective effect of nitric oxide.
American journal of respiratory and critical care medicine 1999;160(4):1179-87.
-
1999: Günther A; Schmidt R; Nix F; Yabut-Perez M; Guth C; Rosseau S; Siebert C; Grimminger F; Morr H; Velcovsky H G; Seeger W
Surfactant abnormalities in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):565-73.
-
1999: Rose F; Zwick K; Ghofrani H A; Sibelius U; Seeger W; Walmrath D; Grimminger F
Prostacyclin enhances stretch-induced surfactant secretion in alveolar epithelial type II cells.
American journal of respiratory and critical care medicine 1999;160(3):846-51.
-
1999: Olschewski H; Ghofrani H A; Walmrath D; Schermuly R; Temmesfeld-Wollbruck B; Grimminger F; Seeger W
Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis.
American journal of respiratory and critical care medicine 1999;160(2):600-7.
-
1999: Grimminger F; Olschewski H; Seeger W
[Vasotropic therapy and artificial respiration for pulmonary hypertension]
Der Internist 1999;40(7):747-55.
-
1999: Olschewski H; Seeger W; Grimminger F
[Physiology and physiopathology of the pulmonary circulation]
Der Internist 1999;40(7):696-709.
-
1999: Lohmeyer J; Friedrich J; Grimminger F; Maus U; Tenter R; Morr H; Velcovsky H G; Seeger W; Rosseau S
Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases.
Clinical and experimental immunology 1999;116(2):340-6.
-
1999: Braun-Dullaeus R C; Feussner M; Walker G; Hopmann H; Kraemer H J; Grimminger F; Tillmanns H; Haberbosch W
Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1999;18(4):328-35.
-
1999: Sibelius U; Schulz E C; Rose F; Hattar K; Jacobs T; Weiss S; Chakraborty T; Seeger W; Grimminger F
Role of Listeria monocytogenes exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C in activation of human neutrophils.
Infection and immunity 1999;67(3):1125-30.
-
1999: Maus U; Rosseau S; Mandrakas N; Schlingensiepen R; Maus R; Muth H; Grimminger F; Seeger W; Lohmeyer J
Cationic lipids employed for antisense oligodeoxynucleotide transport may inhibit vascular cell adhesion molecule-1 expression in human endothelial cells: a word of caution.
Antisense & nucleic acid drug development 1999;9(1):71-80.
-
1999: Weissmann N; Voswinckel R; Hardebusch T; Rosseau S; Ghofrani H A; Schermuly R; Seeger W; Grimminger F
Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction.
The American journal of physiology 1999;276(1 Pt 1):L90-5.
-
1999: Rose F; Kürth-Landwehr C; Sibelius U; Reuner K H; Aktories K; Seeger W; Grimminger F
Role of actin depolymerization in the surfactant secretory response of alveolar epithelial type II cells.
American journal of respiratory and critical care medicine 1999;159(1):206-12.
-
1998: Grimm H; Grimminger F; Korom S; Seeger W
Use of fish oil to prevent graft rejection.
The Proceedings of the Nutrition Society 1998;57(4):577-85.
-
1998: Fink L; Seeger W; Ermert L; Hänze J; Stahl U; Grimminger F; Kummer W; Bohle R M
Real-time quantitative RT-PCR after laser-assisted cell picking.
Nature medicine 1998;4(11):1329-33.
-
1998: Weissmann N; Seeger W; Conzen J; Kiss L; Grimminger F
Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs.
European journal of pharmacology 1998;356(2-3):231-7.
-
1998: Ermert L; Ermert M; Althoff A; Merkle M; Grimminger F; Seeger W
Vasoregulatory prostanoid generation proceeds via cyclooxygenase-2 in noninflamed rat lungs.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1309-14.
-
1998: Kiss L; Bieniek E; Weissmann N; Schutte H; Sibelius U; Gunther A; Bier J; Mayer K; Henneking K; Padberg W; Grimm H; Seeger W; Grimminger F
Simultaneous analysis of 4- and 5-series lipoxygenase and cytochrome P450 products from different biological sources by reversed-phase high-performance liquid chromatographic technique.
Analytical biochemistry 1998;261(1):16-28.
-
1998: Olschewski H; Ghofrani H A; Walmrath D; Temmesfeld-Wollbrück B; Grimminger F; Seeger W
Recovery from circulatory shock in severe primary pulmonary hypertension (PPH) with aerosolization of iloprost.
Intensive care medicine 1998;24(6):631-4.
-
1998: Weissmann N; Grimminger F; Voswinckel R; Conzen J; Seeger W
Nitro blue tetrazolium inhibits but does not mimic hypoxic vasoconstriction in isolated rabbit lungs.
The American journal of physiology 1998;274(5 Pt 1):L721-7.
-
1998: Temmesfeld-Wollbrück B; Szalay A; Mayer K; Olschewski H; Seeger W; Grimminger F
Abnormalities of gastric mucosal oxygenation in septic shock: partial responsiveness to dopexamine.
American journal of respiratory and critical care medicine 1998;157(5 Pt 1):1586-92.
-
1998: Mayser P; Mrowietz U; Arenberger P; Bartak P; Buchvald J; Christophers E; Jablonska S; Salmhofer W; Schill W B; Krämer H J; Schlotzer E; Mayer K; Seeger W; Grimminger F
Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial.
Journal of the American Academy of Dermatology 1998;38(4):539-47.
-
1998: Ermert L; Ermert M; Goppelt-Struebe M; Walmrath D; Grimminger F; Steudel W; Ghofrani H A; Homberger C; Duncker H; Seeger W
Cyclooxygenase isoenzyme localization and mRNA expression in rat lungs.
American journal of respiratory cell and molecular biology 1998;18(4):479-88.
-
1998: Mayer K; Seeger W; Grimminger F
Clinical use of lipids to control inflammatory disease.
Current opinion in clinical nutrition and metabolic care 1998;1(2):179-84.
-
1998: Schütte H; Mayer K; Gessler T; Rühl M; Schlaudraff J; Burger H; Seeger W; Grimminger F
Nitric oxide biosynthesis in an exotoxin-induced septic lung model: role of cNOS and impact on pulmonary hemodynamics.
American journal of respiratory and critical care medicine 1998;157(2):498-504.
-
1998: Sibelius U; Hattar K; Schenkel A; Noll T; Csernok E; Gross W L; Mayet W J; Piper H M; Seeger W; Grimminger F
Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response.
The Journal of experimental medicine 1998;187(4):497-503.
-
1998: Olschewski H; Walmrath D; Schermuly R; Ghofrani H A; Grimminger F; Seeger W
[Prostacyclin and iloprost in aerosol form in severe pulmonary hypertension]
Pneumologie (Stuttgart, Germany) 1998;52(1):3-7.
-
1998: Schütte H; Hermle G; Seeger W; Grimminger F
Vascular distension and continued ventilation are protective in lung ischemia/reperfusion.
American journal of respiratory and critical care medicine 1998;157(1):171-7.
-
1997: Schütte H; Rosseau S; Czymek R; Ermert L; Walmrath D; Krämer H J; Seeger W; Grimminger F
Synergism between endotoxin priming and exotoxin challenge in provoking severe vascular leakage in rabbit lungs.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):819-24.
-
1997: Schermuly R; Schmehl T; Günther A; Grimminger F; Seeger W; Walmrath D
Ultrasonic nebulization for efficient delivery of surfactant in a model of acute lung injury. Impact on gas exchange.
American journal of respiratory and critical care medicine 1997;156(2 Pt 1):445-53.
-
1997: Schütte H; Grimminger F; Otterbein J; Spriestersbach R; Mayer K; Walmrath D; Seeger W
Efficiency of aerosolized nitric oxide donor drugs to achieve sustained pulmonary vasodilation.
The Journal of pharmacology and experimental therapeutics 1997;282(2):985-94.
-
1997: Grimminger F; Rose F; Sibelius U; Meinhardt M; Pötzsch B; Spriestersbach R; Bhakdi S; Suttorp N; Seeger W
Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1909-16.
-
1997: Grimminger F; Mayer K; Seeger W
[Is there a reliable immunotherapy in infection?]
Der Internist 1997;38(6):541-52.
-
1997: Walmrath D; Olschewski H; Grimminger F; Seeger W
[NO and alternative inhalational therapy approaches in pulmonary hypertension]
Der Internist 1997;38(5):453-60.
-
1997: Walmrath D; Schermuly R; Pilch J; Grimminger F; Seeger W
Effects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(5):1084-92.
-
1997: Temmesfeld-Wollbrück B; Szalay A; Olschewski H; Grimminger F; Seeger W
Advantage of buffered solutions or automated capnometry in air-filled balloons for use in gastric tonometry.
Intensive care medicine 1997;23(4):423-7.
-
1997: Grimminger F; Mayer K; Kiss L; Wahn H; Walmrath D; Seeger W
Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply.
American journal of respiratory cell and molecular biology 1997;16(3):317-24.
-
1997: Ermert L; Duncker H R; Brückner H; Grimminger F; Hansen T; Rössig R; Aktories K; Seeger W
Ultrastructural changes of lung capillary endothelium in response to botulinum C2 toxin.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;82(2):382-8.
-
1997: Grimminger F; Wahn H; Mayer K; Kiss L; Walmrath D; Seeger W
Impact of arachidonic versus eicosapentaenoic acid on exotonin-induced lung vascular leakage: relation to 4-series versus 5-series leukotriene generation.
American journal of respiratory and critical care medicine 1997;155(2):513-9.
-
1997: Nowak D; Jörres R; Martinez-Müller L; Grimminger F; Seeger W; Koops F; Magnussen H
Effect of 3 hours of passive smoke exposure in the evening on inflammatory markers in bronchoalveolar and nasal lavage fluid in subjects with mild asthma.
International archives of occupational and environmental health 1997;70(2):85-93.
-
1996: Sibelius U; Chakraborty T; Krögel B; Wolf J; Rose F; Schmidt R; Wehland J; Seeger W; Grimminger F
The listerial exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C synergize to elicit endothelial cell phosphoinositide metabolism.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):4055-60.
-
1996: Krämer H J; Stevens J; Grimminger F; Seeger W
Fish oil fatty acids and human platelets: dose-dependent decrease in dienoic and increase in trienoic thromboxane generation.
Biochemical pharmacology 1996;52(8):1211-7.
-
1996: Grimminger F; Hattar K; Papavassilis C; Temmesfeld B; Csernok E; Gross W L; Seeger W; Sibelius U
Neutrophil activation by anti-proteinase 3 antibodies in Wegener's granulomatosis: role of exogenous arachidonic acid and leukotriene B4 generation.
The Journal of experimental medicine 1996;184(4):1567-72.
-
1996: Schütte H; Lohmeyer J; Rosseau S; Ziegler S; Siebert C; Kielisch H; Pralle H; Grimminger F; Morr H; Seeger W
Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(9):1858-67.
-
1996: Walmrath D; Ghofrani H A; Grimminger F; Seeger W
Synergism of alveolar endotoxin "priming" and intravascular exotoxin challenge in lung injury.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):460-8.
-
1996: Walmrath D; Günther A; Ghofrani H A; Schermuly R; Schneider T; Grimminger F; Seeger W
Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis.
American journal of respiratory and critical care medicine 1996;154(1):57-62.
-
1996: Reinhart K; Wiegand-Löhnert C; Grimminger F; Kaul M; Withington S; Treacher D; Eckart J; Willatts S; Bouza C; Krausch D; Stockenhuber F; Eiselstein J; Daum L; Kempeni J
Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo-controlled, dose-ranging study.
Critical care medicine 1996;24(5):733-42.
-
1996: Olschewski H; Walmrath D; Schermuly R; Ghofrani A; Grimminger F; Seeger W
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension.
Annals of internal medicine 1996;124(9):820-4.
-
1996: Hammes H P; Weiss A; Führer D; Krämer H J; Papavassilis C; Grimminger F
Acceleration of experimental diabetic retinopathy in the rat by omega-3 fatty acids.
Diabetologia 1996;39(3):251-5.
-
1996: Walmrath D; Schneider T; Schermuly R; Olschewski H; Grimminger F; Seeger W
Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 1996;153(3):991-6.
-
1996: Sibelius U; Rose F; Chakraborty T; Darji A; Wehland J; Weiss S; Seeger W; Grimminger F
Listeriolysin is a potent inducer of the phosphatidylinositol response and lipid mediator generation in human endothelial cells.
Infection and immunity 1996;64(2):674-6.
-
1996: Ghofrani H A; Rosseau S; Walmrath D; Kaddus W; Kramer A; Grimminger F; Lohmeyer J; Seeger W
Compartmentalized lung cytokine release in response to intravascular and alveolar endotoxin challenge.
The American journal of physiology 1996;270(1 Pt 1):L62-8.
-
1996: Grimminger F; Grimm H; Führer D; Papavassilis C; Lindemann G; Blecher C; Mayer K; Tabesch F; Krämer H J; Stevens J; Seeger W
Omega-3 lipid infusion in a heart allotransplant model. Shift in fatty acid and lipid mediator profiles and prolongation of transplant survival.
Circulation 1996;93(2):365-71.
-
1996: Günther A; Siebert C; Schmidt R; Ziegler S; Grimminger F; Yabut M; Temmesfeld B; Walmrath D; Morr H; Seeger W
Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema.
American journal of respiratory and critical care medicine 1996;153(1):176-84.
-
1996: Bhakdi S; Walev I; Jonas D; Palmer M; Weller U; Suttorp N; Grimminger F; Seeger W
Pathogenesis of sepsis syndrome: possible relevance of pore-forming bacterial toxins.
Current topics in microbiology and immunology 1996;216():101-18.
-
1995: Seeger W; Walmrath D; Grimminger F
[New supportive therapy measures in acute lung failure]
Der Internist 1995;36(12):1139-49.
-
1995: Seeger W; Walmrath D; Grimminger F
[ARDS. Intensive therapy of acute lung failure]
Der Internist 1995;36(8):785-801.
-
1995: Seeger W; Hansen T; Rössig R; Schmehl T; Schütte H; Krämer H J; Walmrath D; Weissmann N; Grimminger F; Suttorp N
Hydrogen peroxide-induced increase in lung endothelial and epithelial permeability--effect of adenylate cyclase stimulation and phosphodiesterase inhibition.
Microvascular research 1995;50(1):1-17.
-
1995: Grimminger F; Wahn H; Kramer H J; Stevens J; Mayer K; Walmrath D; Seeger W
Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension.
The American journal of physiology 1995;268(6 Pt 2):H2252-9.
-
1995: Ermert L; Brückner H; Walmrath D; Grimminger F; Aktories K; Suttorp N; Duncker H R; Seeger W
Role of endothelial cytoskeleton in high-permeability edema due to botulinum C2 toxin in perfused rabbit lungs.
The American journal of physiology 1995;268(5 Pt 1):L753-61.
-
1995: Grimminger F; Weissmann N; Spriestersbach R; Becker E; Rosseau S; Seeger W
Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs.
The American journal of physiology 1995;268(5 Pt 1):L747-52.
-
1995: Weissmann N; Grimminger F; Walmrath D; Seeger W
Hypoxic vasoconstriction in buffer-perfused rabbit lungs.
Respiration physiology 1995;100(2):159-69.
-
1995: Grimm H; Tibell A; Norrlind B; Schott J; Bohle R M; Papavassilis C; Führer D; Mayer K; Grimminger F
[Immunosuppressive effect of parenteral fat emulsions in defined immunostimulation]
Infusionstherapie und Transfusionsmedizin 1995;22(2):110-6.
-
1995: Grimminger F; Spriestersbach R; Weissmann N; Walmrath D; Seeger W
Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(4):1509-15.
-
1995: Spriestersbach R; Grimminger F; Weissmann N; Walmrath D; Seeger W
On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(4):1502-8.
-
1995: Walmrath D; Schneider T; Pilch J; Schermuly R; Grimminger F; Seeger W
Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis.
American journal of respiratory and critical care medicine 1995;151(3 Pt 1):724-30.
-
1995: Jörres R; Nowak D; Grimminger F; Seeger W; Oldigs M; Magnussen H
The effect of 1 ppm nitrogen dioxide on bronchoalveolar lavage cells and inflammatory mediators in normal and asthmatic subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(3):416-24.
-
1995: Grimminger F; Mayser P
Lipid mediators, free fatty acids and psoriasis.
Prostaglandins, leukotrienes, and essential fatty acids 1995;52(1):1-15.
-
1995: Temmesfeld-Wollbrück B; Walmrath D; Grimminger F; Seeger W
Prevention and therapy of the adult respiratory distress syndrome.
Lung 1995;173(3):139-64.
-
1994: Walmrath D; Ghofrani H A; Rosseau S; Schütte H; Cramer A; Kaddus W; Grimminger F; Bhakdi S; Seeger W
Endotoxin "priming" potentiates lung vascular abnormalities in response to Escherichia coli hemolysin: an example of synergism between endo- and exotoxin.
The Journal of experimental medicine 1994;180(4):1437-43.
-
1994: Bhakdi S; Grimminger F; Suttorp N; Walmrath D; Seeger W
Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection.
Medical microbiology and immunology 1994;183(3):119-44.
-
1994: Walmrath D; Pilch J; Scharmann M; Grimminger F; Seeger W
Severe VA/Q mismatch in perfused lungs evoked by sequential challenge with endotoxin and E. coli hemolysin.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(3):1020-30.
-
1994: Seeger W; Walmrath D; Grimminger F; Rosseau S; Schütte H; Krämer H J; Ermert L; Kiss L
Adult respiratory distress syndrome: model systems using isolated perfused rabbit lungs.
Methods in enzymology 1994;233():549-84.
-
1993: Grimminger F; Führer D; Papavassilis C; Schlotzer E; Mayer K; Heuer K U; Kiss L; Walmrath D; Piberhofer S; Lübbecke F
Influence of intravenous n-3 lipid supplementation on fatty acid profiles and lipid mediator generation in a patient with severe ulcerative colitis.
European journal of clinical investigation 1993;23(11):706-15.
-
1993: Walmrath D; Griebner M; Kolb B; Grimminger F; Galanos C; Schade U; Seeger W
Endotoxin primes perfused rabbit lungs for enhanced vasoconstrictor response to staphylococcal alpha-toxin.
The American review of respiratory disease 1993;148(5):1179-86.
-
1993: Grimminger F; Mayer K; Krämer H J; Stevens J; Walmrath D; Seeger W
Differential vasoconstrictor potencies of free fatty acids in the lung vasculature: 2-versus 3-series prostanoid generation.
The Journal of pharmacology and experimental therapeutics 1993;267(1):259-65.
-
1993: Walmrath D; Schneider T; Pilch J; Grimminger F; Seeger W
Aerosolised prostacyclin in adult respiratory distress syndrome.
Lancet 1993;342(8877):961-2.
-
1993: Grimminger F; Mayser P; Papavassilis C; Thomas M; Schlotzer E; Heuer K U; Führer D; Hinsch K D; Walmrath D; Schill W B
A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis. Rapid improvement of clinical manifestations and changes in neutrophil leukotriene profile.
The Clinical investigator 1993;71(8):634-43.
-
1993: Suttorp N; Fuhrmann M; Tannert-Otto S; Grimminger F; Bhadki S
Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells.
The Journal of experimental medicine 1993;178(1):337-41.
-
1993: Walmrath D; Scharmann M; König R; Pilch J; Grimminger F; Seeger W
Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(4):1972-80.
-
1993: Seeger W; Günther A; Walmrath H D; Grimminger F; Lasch H G
Alveolar surfactant and adult respiratory distress syndrome. Pathogenetic role and therapeutic prospects.
The Clinical investigator 1993;71(3):177-90.
-
1993: Nowak D; Grimminger F; Jörres R; Oldigs M; Rabe K F; Seeger W; Magnussen H
Increased LTB4 metabolites and PGD2 in BAL fluid after methacholine challenge in asthmatic subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(3):405-12.
-
1992: Seeger W; Grimminger F; Walmrath D
[ARDS: possible role of bacterial exotoxin]
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1992;27(5):310-4.
-
1992: Grimminger F; Dürr U; Seeger W
Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply.
Molecular pharmacology 1992;41(4):757-66.
-
1992: Ermert L; Rousseau S; Schütte H; Birkemeyer R G; Grimminger F; Bhakdi S; Duncker H R; Seeger W
Induction of severe vascular leakage by low doses of Escherichia coli hemolysin in perfused rabbit lungs.
Laboratory investigation; a journal of technical methods and pathology 1992;66(3):362-9.
-
1992: Grimminger F; von Kürten I; Walmrath D; Seeger W
Type II alveolar epithelial eicosanoid metabolism: predominance of cyclooxygenase pathways and transcellular lipoxygenase metabolism in co-culture with neutrophils.
American journal of respiratory cell and molecular biology 1992;6(1):9-16.
-
1992: Walmrath D; König R; Ernst C; Brückner H; Grimminger F; Seeger W
Ventilation-perfusion relationships in isolated blood-free perfused rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(1):374-82.
-
1991: Walmrath D; Schneider U; Kreusler B; Grimminger F; Ennis M; Seeger W
Intravascular anti-IgE challenge in perfused lungs: mediator release and vascular pressor response.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(6):2499-506.
-
1991: Grimminger F; Sibelius U; Bhakdi S; Suttorp N; Seeger W
Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils.
The Journal of clinical investigation 1991;88(5):1531-9.
-
1991: Schütte H; Rosseau S; Walmrath D; Grimminger F; Ernst C; Seeger W
Neutrophil passage through isolated perfused rabbit lungs.
The American journal of physiology 1991;261(4 Pt 2):H1317-23.
-
1991: Grimminger F; Sibelius U; Aktories K; Suttorp N; Seeger W
Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.
Molecular pharmacology 1991;40(4):563-71.
-
1991: Grimminger F; Sibelius U; Aktories K; Just I; Seeger W
Suppression of cytoskeletal rearrangement in activated human neutrophils by botulinum C2 toxin. Impact on cellular signal transduction.
The Journal of biological chemistry 1991;266(29):19276-82.
-
1991: Grimminger F; Scholz C; Bhakdi S; Seeger W
Subhemolytic doses of Escherichia coli hemolysin evoke large quantities of lipoxygenase products in human neutrophils.
The Journal of biological chemistry 1991;266(22):14262-9.
-
1991: Grimminger F; Sibelius U; Seeger W
Amplification of LTB4 generation in AM-PMN cocultures: transcellular 5-lipoxygenase metabolism.
The American journal of physiology 1991;261(2 Pt 1):L195-203.
-
1991: Suttorp N; Polley M; Seybold J; Schnittler H; Seeger W; Grimminger F; Aktories K
Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro.
The Journal of clinical investigation 1991;87(5):1575-84.
-
1991: Seeger W; Obernitz R; Thomas M; Walmrath D; Suttorn N; Holland I B; Grimminger F; Eberspächer B; Hugo F; Bhakdi S
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.
The American review of respiratory disease 1991;143(4 Pt 1):797-805.
-
1991: Grimminger F; Kreusler B; Schneider U; von Witzleben E; Walmrath D; Neppert J; Seeger W
Human leukoagglutinating antibody evokes cooperative leukotriene synthesis in pulmonary microvasculature. Model of transfusion-related acute lung injury.
Circulation research 1991;68(2):503-12.
-
1991: Grimminger F; Walmrath D; Walter H; Lutz F; Seeger W
Induction of vascular injury by Pseudomonas aeruginosa cytotoxin in rabbit lungs is associated with the generation of different leukotrienes and hydroxyeicosatetraenoic acids.
The Journal of infectious diseases 1991;163(2):362-70.
-
1991: Seeger W; Grimminger F
Leukotrienes and ARDS.
Intensive care medicine 1991;17(1):65-6.
-
1991: Seeger W; Grimminger F; Barden M; Becker G; Lohmeyer J; Heinrich D; Lasch H G
Omega-oxidized leukotriene B4 detected in the broncho-alveolar lavage fluid of patients with non-cardiogenic pulmonary edema, but not in those with cardiogenic edema.
Intensive care medicine 1991;17(1):1-6.
-
1990: Seeger W; Schneider U; Kreusler B; von Witzleben E; Walmrath D; Grimminger F; Neppert J
Reproduction of transfusion-related acute lung injury in an ex vivo lung model.
Blood 1990;76(7):1438-44.
-
1990: Grimminger F; Thomas M; Obernitz R; Walmrath D; Bhakdi S; Seeger W
Inflammatory lipid mediator generation elicited by viable hemolysin-forming Escherichia coli in lung vasculature.
The Journal of experimental medicine 1990;172(4):1115-25.
-
1990: Grimminger F; Walmrath D; Birkemeyer R G; Bhakdi S; Seeger W
Leukotriene and hydroxyeicosatetraenoic acid generation elicited by low doses of Escherichia coli hemolysin in rabbit lungs.
Infection and immunity 1990;58(8):2659-63.
-
1990: Grimminger F; Kreusler B; Schneider U; Becker G; Seeger W
Influence of microvascular adherence on neutrophil leukotriene generation. Evidence for cooperative eicosanoid synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1866-72.
-
1990: Seeger W; Grimminger F
[The role of arachidonic acid metabolites in the pathogenesis of bronchial asthma]
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1990;96():685-93.
-
1988: Grimminger F; Menger M; Becker G; Seeger W
Potentiation of leukotriene production following sequestration of neutrophils in isolated lungs: indirect evidence for intercellular leukotriene A4 transfer.
Blood 1988;72(5):1687-92.
-
1988: Grimminger F; Becker G; Seeger W
High yield enzymatic conversion of intravascular leukotriene A4 in blood-free perfused lungs.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2431-6.
-
1987: Seeger W; Menger M; Walmrath D; Becker G; Grimminger F; Neuhof H
Arachidonic acid lipoxygenase pathways and increased vascular permeability in isolated rabbit lungs.
The American review of respiratory disease 1987;136(4):964-72.
Sign-in to see more
